CTTNBP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ionotropic glutamate receptor signaling pathway (GO:0035235)5.76147056
2glutamate receptor signaling pathway (GO:0007215)5.32569626
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.23004229
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.21962269
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.16548382
6vocalization behavior (GO:0071625)5.15536370
7protein localization to synapse (GO:0035418)5.08995799
8synaptic transmission, glutamatergic (GO:0035249)4.97384078
9neuron cell-cell adhesion (GO:0007158)4.92081467
10regulation of glutamate receptor signaling pathway (GO:1900449)4.72487005
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.60333408
12neuron-neuron synaptic transmission (GO:0007270)4.58190500
13presynaptic membrane assembly (GO:0097105)4.55162650
14synaptic vesicle exocytosis (GO:0016079)4.47287522
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.42910392
16neurotransmitter-gated ion channel clustering (GO:0072578)4.42855339
17G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.42759627
18glutamate secretion (GO:0014047)4.39584074
19locomotory exploration behavior (GO:0035641)4.31014551
20neuron recognition (GO:0008038)4.28852031
21neuronal action potential propagation (GO:0019227)4.28192972
22pyrimidine nucleobase catabolic process (GO:0006208)4.23004675
23synaptic vesicle docking involved in exocytosis (GO:0016081)4.17609806
24regulation of long-term neuronal synaptic plasticity (GO:0048169)4.13080729
25presynaptic membrane organization (GO:0097090)4.12760548
26regulation of neuronal synaptic plasticity (GO:0048168)4.09946474
27gamma-aminobutyric acid signaling pathway (GO:0007214)4.04019064
28regulation of excitatory postsynaptic membrane potential (GO:0060079)4.03717493
29postsynaptic membrane organization (GO:0001941)4.01805630
30axonal fasciculation (GO:0007413)4.00779151
31long-term memory (GO:0007616)3.91515221
32regulation of synaptic vesicle exocytosis (GO:2000300)3.90045271
33membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.84653313
34regulation of postsynaptic membrane potential (GO:0060078)3.82578546
35synaptic vesicle maturation (GO:0016188)3.78390175
36exploration behavior (GO:0035640)3.77755361
37regulation of dendritic spine morphogenesis (GO:0061001)3.73801865
38positive regulation of synapse maturation (GO:0090129)3.73193000
39regulation of synaptic vesicle transport (GO:1902803)3.71127492
40transmission of nerve impulse (GO:0019226)3.68320886
41long-term synaptic potentiation (GO:0060291)3.64281368
42regulation of synaptic plasticity (GO:0048167)3.64280246
43limb bud formation (GO:0060174)3.63743781
44behavioral defense response (GO:0002209)3.61641306
45behavioral fear response (GO:0001662)3.61641306
46regulation of synaptic transmission, glutamatergic (GO:0051966)3.58761127
47regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.58325901
48positive regulation of membrane potential (GO:0045838)3.57537481
49cerebral cortex radially oriented cell migration (GO:0021799)3.56372116
50response to histamine (GO:0034776)3.56035557
51axon ensheathment in central nervous system (GO:0032291)3.51562916
52central nervous system myelination (GO:0022010)3.51562916
53negative regulation of dendrite development (GO:2000171)3.51272395
54positive regulation of neurotransmitter secretion (GO:0001956)3.45789747
55negative regulation of synaptic transmission, GABAergic (GO:0032229)3.43580171
56dendritic spine morphogenesis (GO:0060997)3.41973149
57regulation of synapse structural plasticity (GO:0051823)3.41950793
58fear response (GO:0042596)3.40041212
59regulation of collateral sprouting (GO:0048670)3.38826686
60nucleobase catabolic process (GO:0046113)3.38599852
61regulation of vesicle fusion (GO:0031338)3.35433186
62startle response (GO:0001964)3.34022758
63neurotransmitter secretion (GO:0007269)3.31839532
64regulation of dendritic spine development (GO:0060998)3.31124436
65regulation of glutamate secretion (GO:0014048)3.29149682
66regulation of axon regeneration (GO:0048679)3.28166692
67regulation of neuron projection regeneration (GO:0070570)3.28166692
68central nervous system projection neuron axonogenesis (GO:0021952)3.27253564
69gamma-aminobutyric acid transport (GO:0015812)3.27245291
70membrane depolarization (GO:0051899)3.27152974
71negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.24057913
72positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.23881557
73membrane depolarization during action potential (GO:0086010)3.22933358
74positive regulation of dendritic spine morphogenesis (GO:0061003)3.22624864
75synaptic vesicle endocytosis (GO:0048488)3.22463023
76regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.21686314
77positive regulation of dendritic spine development (GO:0060999)3.17940271
78learning (GO:0007612)3.17570892
79G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.17108403
80negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.14086302
81negative regulation of translation, ncRNA-mediated (GO:0040033)3.14086302
82regulation of translation, ncRNA-mediated (GO:0045974)3.14086302
83regulation of synapse maturation (GO:0090128)3.10049703
84positive regulation of neurotransmitter transport (GO:0051590)3.07291482
85dendritic spine organization (GO:0097061)3.07147481
86behavioral response to cocaine (GO:0048148)3.05363908
87serotonin metabolic process (GO:0042428)3.05351435
88regulation of neurotransmitter secretion (GO:0046928)3.05288643
89long term synaptic depression (GO:0060292)3.04240883
90dendrite morphogenesis (GO:0048813)3.03896652
91cochlea development (GO:0090102)3.03862575
92C4-dicarboxylate transport (GO:0015740)2.98967763
93auditory behavior (GO:0031223)2.98911364
94innervation (GO:0060384)2.98090853
95cellular potassium ion homeostasis (GO:0030007)2.97333471
96positive regulation of synaptic transmission, GABAergic (GO:0032230)2.96515270
97establishment of mitochondrion localization (GO:0051654)2.95876807
98positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.94097934
99central nervous system neuron axonogenesis (GO:0021955)2.93800993
100synaptic transmission (GO:0007268)2.93226901
101regulation of synaptic transmission (GO:0050804)2.93189676
102ephrin receptor signaling pathway (GO:0048013)2.90591052
103layer formation in cerebral cortex (GO:0021819)2.90201480
104negative regulation of amino acid transport (GO:0051956)2.89587607
105cerebellar granule cell differentiation (GO:0021707)2.88791695
106synapse assembly (GO:0007416)2.87335171
107cerebellar Purkinje cell differentiation (GO:0021702)2.87070883
108neurotransmitter transport (GO:0006836)2.86613855
109regulation of female receptivity (GO:0045924)2.84558666
110detection of calcium ion (GO:0005513)2.84351204
111neuronal ion channel clustering (GO:0045161)2.84269090
112positive regulation of synaptic transmission (GO:0050806)2.84166617
113mechanosensory behavior (GO:0007638)2.83749770
114positive regulation of synapse assembly (GO:0051965)2.83431700
115proline transport (GO:0015824)2.83156613
116righting reflex (GO:0060013)2.82433282
117regulation of respiratory system process (GO:0044065)2.82399934
118membrane hyperpolarization (GO:0060081)2.82081647
119L-amino acid import (GO:0043092)2.78519801
120olfactory bulb development (GO:0021772)2.76801051
121atrial cardiac muscle cell action potential (GO:0086014)2.76649855
122hindbrain development (GO:0030902)2.75706006
123neurotransmitter uptake (GO:0001504)2.73440924
124long-chain fatty acid biosynthetic process (GO:0042759)2.71234506
125glycosphingolipid biosynthetic process (GO:0006688)2.69542007
126adult walking behavior (GO:0007628)2.68813463
127negative regulation of axonogenesis (GO:0050771)2.65779611
128response to pheromone (GO:0019236)2.61218742
129regulation of timing of cell differentiation (GO:0048505)2.57114006
130response to auditory stimulus (GO:0010996)2.54821504
131cell migration in hindbrain (GO:0021535)2.54675210
132negative regulation of axon extension (GO:0030517)2.54564164
133retinal cone cell development (GO:0046549)2.54306031
134establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.51292369
135mitochondrion transport along microtubule (GO:0047497)2.51292369
136regulation of synapse assembly (GO:0051963)2.49609845
137membrane assembly (GO:0071709)2.47527066
138retina layer formation (GO:0010842)2.45979313
139negative regulation of cytosolic calcium ion concentration (GO:0051481)2.45035452
140negative regulation of astrocyte differentiation (GO:0048712)2.41866419
141spinal cord development (GO:0021510)2.41195935
142synapse organization (GO:0050808)2.41139136

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.56627082
2GBX2_23144817_ChIP-Seq_PC3_Human4.40126993
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02313114
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98993677
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.94156209
6* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.62870213
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.56361170
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.56361170
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51870434
10SALL1_21062744_ChIP-ChIP_HESCs_Human2.50810999
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.50346150
12* EZH2_27304074_Chip-Seq_ESCs_Mouse2.45432154
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.44435233
14* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38133384
15REST_21632747_ChIP-Seq_MESCs_Mouse2.33559555
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32698928
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26235901
18DROSHA_22980978_ChIP-Seq_HELA_Human2.24218174
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.21242492
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.05538156
21* RNF2_27304074_Chip-Seq_ESCs_Mouse2.04212310
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.02673976
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.97558395
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.95815395
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95413957
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94653638
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94640486
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.91227191
29TAF15_26573619_Chip-Seq_HEK293_Human1.84124635
30EWS_26573619_Chip-Seq_HEK293_Human1.81739887
31SMAD4_21799915_ChIP-Seq_A2780_Human1.79620321
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.78757842
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.71476326
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.70806162
35AR_21572438_ChIP-Seq_LNCaP_Human1.68099654
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67439105
37* P300_19829295_ChIP-Seq_ESCs_Human1.66034604
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64992715
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.63685560
40* IKZF1_21737484_ChIP-ChIP_HCT116_Human1.62954241
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.58109102
42SMAD3_21741376_ChIP-Seq_EPCs_Human1.54518450
43TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54074219
44FUS_26573619_Chip-Seq_HEK293_Human1.52303770
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51958062
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.50170857
47* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.47511063
48RBPJ_22232070_ChIP-Seq_NCS_Mouse1.45917234
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.44397515
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44070168
51VDR_22108803_ChIP-Seq_LS180_Human1.41784518
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39879558
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.37221348
54* STAT3_23295773_ChIP-Seq_U87_Human1.37074832
55SMAD_19615063_ChIP-ChIP_OVARY_Human1.36145010
56* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35570546
57* AR_25329375_ChIP-Seq_VCAP_Human1.35403973
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35021306
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31355717
60SOX9_26525672_Chip-Seq_HEART_Mouse1.31162720
61ZNF274_21170338_ChIP-Seq_K562_Hela1.30861312
62MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30364973
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.29870595
64* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29340925
65LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29208709
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.28943954
67STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27591756
68* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24412670
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.23764092
70VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.23112361
71SMAD3_21741376_ChIP-Seq_ESCs_Human1.22601739
72ARNT_22903824_ChIP-Seq_MCF-7_Human1.22598062
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22298590
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21398156
75CBP_20019798_ChIP-Seq_JUKART_Human1.20182308
76IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20182308
77* TCF4_23295773_ChIP-Seq_U87_Human1.19520034
78* TCF4_22108803_ChIP-Seq_LS180_Human1.18275723
79AHR_22903824_ChIP-Seq_MCF-7_Human1.17996711
80RNF2_27304074_Chip-Seq_NSC_Mouse1.17155725
81TP53_16413492_ChIP-PET_HCT116_Human1.16334271
82TP53_18474530_ChIP-ChIP_U2OS_Human1.16022110
83E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.15627480
84RING1B_27294783_Chip-Seq_ESCs_Mouse1.15423679
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15100980
86* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.14530858
87AR_19668381_ChIP-Seq_PC3_Human1.14394768
88EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14054717
89BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.13197147
90MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12646920
91KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12395523
92KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12042015
93PRDM14_20953172_ChIP-Seq_ESCs_Human1.11838107
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11792172
95TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11774106
96RUNX2_22187159_ChIP-Seq_PCA_Human1.11671725
97IGF1R_20145208_ChIP-Seq_DFB_Human1.11662850
98ERG_21242973_ChIP-ChIP_JURKAT_Human1.10269952
99MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09286564
100* NANOG_18555785_Chip-Seq_ESCs_Mouse1.07917421
101CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07873472
102* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07385854
103* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07000421
104KDM2B_26808549_Chip-Seq_REH_Human1.06334044
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06240495
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06240495
107TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.05849338
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.04537259
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.03844702
110* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03099984
111SMAD3_21741376_ChIP-Seq_HESCs_Human1.02977474
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02793954
113BCAT_22108803_ChIP-Seq_LS180_Human1.01920873
114TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01842097
115P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00685438
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00194406
117JUN_21703547_ChIP-Seq_K562_Human0.98287728
118MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97757248
119EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96436757
120E2F1_18555785_Chip-Seq_ESCs_Mouse0.95535615
121P53_22387025_ChIP-Seq_ESCs_Mouse0.91978199
122SMAD4_21741376_ChIP-Seq_HESCs_Human0.90849198
123ER_23166858_ChIP-Seq_MCF-7_Human0.90258536

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.42320434
2MP0003880_abnormal_central_pattern5.79917419
3MP0003635_abnormal_synaptic_transmissio4.01953761
4MP0009745_abnormal_behavioral_response3.54297740
5MP0004270_analgesia3.50697506
6MP0002063_abnormal_learning/memory/cond3.35082556
7MP0002822_catalepsy3.14180474
8MP0001968_abnormal_touch/_nociception3.06943133
9MP0002064_seizures3.03744110
10MP0002572_abnormal_emotion/affect_behav2.89174105
11MP0002736_abnormal_nociception_after2.64876297
12MP0002272_abnormal_nervous_system2.62028221
13MP0001501_abnormal_sleep_pattern2.57884008
14MP0002735_abnormal_chemical_nociception2.56770777
15MP0009046_muscle_twitch2.45338133
16MP0001486_abnormal_startle_reflex2.42815932
17MP0002734_abnormal_mechanical_nocicepti2.22575374
18MP0008877_abnormal_DNA_methylation2.20472835
19MP0001440_abnormal_grooming_behavior2.14129653
20MP0005423_abnormal_somatic_nervous2.12258629
21MP0003787_abnormal_imprinting1.98343293
22MP0000778_abnormal_nervous_system1.97694234
23MP0002067_abnormal_sensory_capabilities1.95312023
24MP0001188_hyperpigmentation1.89607277
25MP0002733_abnormal_thermal_nociception1.77809142
26MP0001970_abnormal_pain_threshold1.73371450
27MP0005646_abnormal_pituitary_gland1.72044048
28MP0002557_abnormal_social/conspecific_i1.69352458
29MP0002184_abnormal_innervation1.66932880
30MP0006276_abnormal_autonomic_nervous1.62229279
31MP0003121_genomic_imprinting1.60659383
32MP0009780_abnormal_chondrocyte_physiolo1.60088984
33MP0000569_abnormal_digit_pigmentation1.59270999
34MP0001529_abnormal_vocalization1.58364220
35MP0003329_amyloid_beta_deposits1.57860110
36MP0008569_lethality_at_weaning1.55678014
37MP0004924_abnormal_behavior1.50968405
38MP0005386_behavior/neurological_phenoty1.50968405
39MP0001984_abnormal_olfaction1.48540716
40MP0003879_abnormal_hair_cell1.47271764
41MP0006292_abnormal_olfactory_placode1.45111597
42MP0001502_abnormal_circadian_rhythm1.43377510
43MP0001905_abnormal_dopamine_level1.41155726
44MP0000955_abnormal_spinal_cord1.41092194
45MP0005171_absent_coat_pigmentation1.38942688
46MP0004811_abnormal_neuron_physiology1.37610441
47MP0002882_abnormal_neuron_morphology1.37203365
48MP0004885_abnormal_endolymph1.36314752
49MP0005409_darkened_coat_color1.33465428
50MP0003890_abnormal_embryonic-extraembry1.31108198
51MP0002066_abnormal_motor_capabilities/c1.29044308
52MP0004858_abnormal_nervous_system1.25694971
53MP0002909_abnormal_adrenal_gland1.25597894
54MP0003119_abnormal_digestive_system1.25580664
55MP0002876_abnormal_thyroid_physiology1.15020309
56MP0002233_abnormal_nose_morphology1.14663871
57MP0004142_abnormal_muscle_tone1.13098697
58MP0003633_abnormal_nervous_system1.13045352
59MP0001299_abnormal_eye_distance/1.12574892
60MP0002751_abnormal_autonomic_nervous1.11095638
61MP0005253_abnormal_eye_physiology1.09876623
62MP0010386_abnormal_urinary_bladder1.06258760
63MP0002152_abnormal_brain_morphology1.03332788
64MP0005645_abnormal_hypothalamus_physiol1.01733141
65MP0003631_nervous_system_phenotype1.01175544
66MP0008057_abnormal_DNA_replication1.00584397
67MP0005551_abnormal_eye_electrophysiolog0.99262010
68MP0004145_abnormal_muscle_electrophysio0.98529665
69MP0001177_atelectasis0.95615319
70MP0001293_anophthalmia0.95590090
71MP0004742_abnormal_vestibular_system0.93281843
72MP0002229_neurodegeneration0.91533390
73MP0001963_abnormal_hearing_physiology0.91485319
74MP0001485_abnormal_pinna_reflex0.90835328
75MP0002837_dystrophic_cardiac_calcinosis0.90341890
76MP0003122_maternal_imprinting0.89492179
77MP0002069_abnormal_eating/drinking_beha0.88758862
78MP0008789_abnormal_olfactory_epithelium0.88483207
79MP0003937_abnormal_limbs/digits/tail_de0.88331805
80MP0003123_paternal_imprinting0.88169009
81MP0004085_abnormal_heartbeat0.88156206
82MP0003718_maternal_effect0.83263300
83MP0003195_calcinosis0.82181517
84MP0002938_white_spotting0.81911391
85MP0000631_abnormal_neuroendocrine_gland0.81832442
86MP0003136_yellow_coat_color0.81734994
87MP0002752_abnormal_somatic_nervous0.81214468
88MP0002638_abnormal_pupillary_reflex0.80127894
89MP0005195_abnormal_posterior_eye0.79995621
90MP0005187_abnormal_penis_morphology0.78762884
91MP0005367_renal/urinary_system_phenotyp0.78440319
92MP0000516_abnormal_urinary_system0.78440319
93MP0003567_abnormal_fetal_cardiomyocyte0.78069263
94MP0004147_increased_porphyrin_level0.77785549
95MP0008874_decreased_physiological_sensi0.77142661
96MP0003632_abnormal_nervous_system0.76993259
97MP0000049_abnormal_middle_ear0.75355747
98MP0000647_abnormal_sebaceous_gland0.74812660
99MP0000026_abnormal_inner_ear0.73702711
100MP0000462_abnormal_digestive_system0.72588037
101MP0000920_abnormal_myelination0.72038036
102MP0000751_myopathy0.72000422
103MP0005499_abnormal_olfactory_system0.71490877
104MP0005394_taste/olfaction_phenotype0.71490877
105MP0004484_altered_response_of0.70006274
106MP0002234_abnormal_pharynx_morphology0.68590823
107MP0003283_abnormal_digestive_organ0.68361705
108MP0000678_abnormal_parathyroid_gland0.67765345
109MP0001765_abnormal_ion_homeostasis0.67502727
110MP0003634_abnormal_glial_cell0.65619329
111MP0004215_abnormal_myocardial_fiber0.64738031
112MP0008872_abnormal_physiological_respon0.64366760
113MP0005535_abnormal_body_temperature0.64237837
114MP0003137_abnormal_impulse_conducting0.62021841
115MP0010234_abnormal_vibrissa_follicle0.61886118
116MP0001664_abnormal_digestion0.61819693
117MP0003690_abnormal_glial_cell0.61776531
118MP0004043_abnormal_pH_regulation0.61434156
119MP0003938_abnormal_ear_development0.61068292
120MP0003861_abnormal_nervous_system0.58930708
121MP0005595_abnormal_vascular_smooth0.58052662
122MP0003075_altered_response_to0.56470688
123MP0002102_abnormal_ear_morphology0.56133903
124MP0006072_abnormal_retinal_apoptosis0.54039331
125MP0004133_heterotaxia0.51811231
126MP0000604_amyloidosis0.51367990

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.76232417
2Focal seizures (HP:0007359)5.73809968
3Myokymia (HP:0002411)5.61382390
4Epileptic encephalopathy (HP:0200134)5.25010646
5Atonic seizures (HP:0010819)4.91780048
6Hyperventilation (HP:0002883)4.82539870
7Febrile seizures (HP:0002373)4.79669392
8Absence seizures (HP:0002121)4.09950804
9Dialeptic seizures (HP:0011146)4.09782251
10Visual hallucinations (HP:0002367)4.05306668
11Progressive cerebellar ataxia (HP:0002073)4.05272249
12Broad-based gait (HP:0002136)4.04607140
13Abnormality of the labia minora (HP:0012880)3.89388465
14Generalized tonic-clonic seizures (HP:0002069)3.71732810
15Gaze-evoked nystagmus (HP:0000640)3.49268894
16Amblyopia (HP:0000646)3.32629925
17Drooling (HP:0002307)3.25522007
18Excessive salivation (HP:0003781)3.25522007
19Dysmetria (HP:0001310)3.19453454
20Protruding tongue (HP:0010808)3.08136211
21Supranuclear gaze palsy (HP:0000605)3.07991617
22Dysdiadochokinesis (HP:0002075)2.97870833
23Truncal ataxia (HP:0002078)2.95890650
24Decreased circulating renin level (HP:0003351)2.92852572
25Poor eye contact (HP:0000817)2.86382978
26Cerebral inclusion bodies (HP:0100314)2.84345005
27Neurofibrillary tangles (HP:0002185)2.81978257
28Epileptiform EEG discharges (HP:0011182)2.80582104
29Absent speech (HP:0001344)2.80500021
30Impaired vibration sensation in the lower limbs (HP:0002166)2.79797286
31Scanning speech (HP:0002168)2.79767020
32Hemiparesis (HP:0001269)2.74139050
33Action tremor (HP:0002345)2.68801505
34Impaired smooth pursuit (HP:0007772)2.63619744
35Genetic anticipation (HP:0003743)2.53003873
36Diplopia (HP:0000651)2.52525938
37Abnormality of binocular vision (HP:0011514)2.52525938
38Abnormal social behavior (HP:0012433)2.50164423
39Impaired social interactions (HP:0000735)2.50164423
40Anxiety (HP:0000739)2.49874602
41Blue irides (HP:0000635)2.48456755
42Increased circulating renin level (HP:0000848)2.47899546
43Hepatoblastoma (HP:0002884)2.45701309
44Thickened helices (HP:0000391)2.44835305
45Abnormality of the lower motor neuron (HP:0002366)2.44065271
46EEG with generalized epileptiform discharges (HP:0011198)2.39962175
47Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.38354416
48Depression (HP:0000716)2.37924715
49Astrocytoma (HP:0009592)2.36964723
50Abnormality of the astrocytes (HP:0100707)2.36964723
51Urinary bladder sphincter dysfunction (HP:0002839)2.32826111
52Volvulus (HP:0002580)2.30896339
53Colon cancer (HP:0003003)2.29646151
54Abnormality of salivation (HP:0100755)2.29461964
55Genital tract atresia (HP:0001827)2.29183982
56Renal hypoplasia (HP:0000089)2.28376163
57Stereotypic behavior (HP:0000733)2.27528067
58Intestinal atresia (HP:0011100)2.27221951
59Optic nerve hypoplasia (HP:0000609)2.22571780
60Vaginal atresia (HP:0000148)2.22138768
61Abnormality of ocular smooth pursuit (HP:0000617)2.21289181
62Cutaneous finger syndactyly (HP:0010554)2.21182877
63Abnormal eating behavior (HP:0100738)2.20004934
64Ankle clonus (HP:0011448)2.17590167
65Aplasia/Hypoplasia of the sternum (HP:0006714)2.17500528
66Ependymoma (HP:0002888)2.17476299
67Retinal dysplasia (HP:0007973)2.15918456
68Cupped ear (HP:0000378)2.15392032
69Spastic gait (HP:0002064)2.15135786
70Fair hair (HP:0002286)2.15120513
71Hypsarrhythmia (HP:0002521)2.14860161
72Widely spaced teeth (HP:0000687)2.14429521
73Postural instability (HP:0002172)2.13666313
74Pancreatic fibrosis (HP:0100732)2.12549346
75Exotropia (HP:0000577)2.10398620
76Aqueductal stenosis (HP:0002410)2.09250359
77Megalencephaly (HP:0001355)2.09213022
78Oligodactyly (hands) (HP:0001180)2.09024489
79Generalized hypopigmentation of hair (HP:0011358)2.06424800
80Abnormality of the corticospinal tract (HP:0002492)2.05615369
81Neoplasm of the oral cavity (HP:0100649)2.05124156
82Septo-optic dysplasia (HP:0100842)2.02848918
83Clumsiness (HP:0002312)2.01285751
84Abnormal hair whorl (HP:0010721)2.01027700
85Glioma (HP:0009733)2.00482282
86Hyperkalemia (HP:0002153)1.98802635
87Anophthalmia (HP:0000528)1.98415229
88Insidious onset (HP:0003587)1.97161447
89Termporal pattern (HP:0011008)1.97161447
90Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.96935107
91Inability to walk (HP:0002540)1.95302238
92Limb dystonia (HP:0002451)1.94897890
93Absent/shortened dynein arms (HP:0200106)1.94762789
94Dynein arm defect of respiratory motile cilia (HP:0012255)1.94762789
95Aplasia involving bones of the extremities (HP:0009825)1.91441538
96Aplasia involving bones of the upper limbs (HP:0009823)1.91441538
97Aplasia of the phalanges of the hand (HP:0009802)1.91441538
98Esotropia (HP:0000565)1.91180086
99Urinary urgency (HP:0000012)1.90885854
100Gastroesophageal reflux (HP:0002020)1.90438774
101Gait imbalance (HP:0002141)1.89924219
102Impaired vibratory sensation (HP:0002495)1.89110039
103Inappropriate behavior (HP:0000719)1.88929680
104Lower limb amyotrophy (HP:0007210)1.88342444
105Cutaneous syndactyly (HP:0012725)1.87471515
106Hyperactive renin-angiotensin system (HP:0000841)1.86091746
107Polyphagia (HP:0002591)1.85681391
108Incomplete penetrance (HP:0003829)1.85443315
109Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.85360347
110Degeneration of the lateral corticospinal tracts (HP:0002314)1.85360347
111Bradykinesia (HP:0002067)1.85059481
112Deeply set eye (HP:0000490)1.83095386
113Status epilepticus (HP:0002133)1.83063799
114Generalized myoclonic seizures (HP:0002123)1.83034312
115Gait ataxia (HP:0002066)1.82557378
116Lower limb muscle weakness (HP:0007340)1.82382371
117Pendular nystagmus (HP:0012043)1.82056304
118Dysmetric saccades (HP:0000641)1.82035190
119Intention tremor (HP:0002080)1.81980677
120Hemiplegia (HP:0002301)1.79603878
121Progressive inability to walk (HP:0002505)1.79383088
122Torticollis (HP:0000473)1.78841766
123Nephrogenic diabetes insipidus (HP:0009806)1.78553822
124Bifid tongue (HP:0010297)1.78155347
125Preaxial foot polydactyly (HP:0001841)1.77992792
126Nephronophthisis (HP:0000090)1.76502793
127True hermaphroditism (HP:0010459)1.76191051
128Fetal akinesia sequence (HP:0001989)1.75504565
129Bilateral microphthalmos (HP:0007633)1.75495615
130Confusion (HP:0001289)1.74601206
131Specific learning disability (HP:0001328)1.74422371
132Labial hypoplasia (HP:0000066)1.73657663
133Syncope (HP:0001279)1.72983679
134Poor coordination (HP:0002370)1.71505449
135Gastrointestinal atresia (HP:0002589)1.71476320
136Lissencephaly (HP:0001339)1.70795332
137Obstructive sleep apnea (HP:0002870)1.70285569
138Pancreatic cysts (HP:0001737)1.70108723
139Medial flaring of the eyebrow (HP:0010747)1.68657686
140Autism (HP:0000717)1.68603716
141Psychosis (HP:0000709)1.67821475
142Vitreoretinal degeneration (HP:0000655)1.66890231
143Choanal stenosis (HP:0000452)1.65671148
144Focal dystonia (HP:0004373)1.65082015
145Abolished electroretinogram (ERG) (HP:0000550)1.65071335
146Congenital primary aphakia (HP:0007707)1.64542488
147Abnormality of midbrain morphology (HP:0002418)1.64262529
148Molar tooth sign on MRI (HP:0002419)1.64262529
149Hypoplastic female external genitalia (HP:0012815)1.64148191
150Abnormality of the antihelix (HP:0009738)1.63827129
151Agnosia (HP:0010524)1.63614427
152Absent eyebrow (HP:0002223)1.59924771
153Tented upper lip vermilion (HP:0010804)1.59455788
154Postaxial hand polydactyly (HP:0001162)1.58947079

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA46.15189950
2NTRK35.96235758
3WNK34.27290754
4TNIK3.47075310
5CASK3.24948453
6MAP3K42.62870136
7MAP2K72.56712746
8FRK2.51497944
9RIPK42.47496392
10MAP3K92.31687946
11PRPF4B2.02716686
12MARK12.01391085
13DAPK21.98103675
14MKNK21.86895620
15MINK11.86789405
16FGFR21.75603695
17MAP4K21.66197968
18PLK21.59603221
19NTRK21.59255944
20DYRK21.55681546
21FES1.49425744
22BMPR21.48522340
23MAPK131.48455926
24MAP2K41.46449575
25KSR11.45214930
26CAMK2B1.44423601
27DAPK11.44063654
28PAK61.41410941
29CDK51.37693976
30SIK21.36390187
31MAP3K121.32053086
32CAMK2A1.30476633
33CCNB11.30119861
34MKNK11.29498243
35AKT31.27929929
36PTK2B1.26896073
37NTRK11.22033818
38KSR21.19069001
39NUAK11.18792125
40PRKCG1.18063002
41GRK51.15394744
42PNCK1.15159299
43TRIM281.14386342
44PRKD31.12571567
45CDK191.10746449
46MAP3K131.10250641
47OXSR11.09313881
48CSNK1G11.08730408
49CAMK1G1.05038032
50NME11.03363055
51MARK20.99452748
52TAF10.98124377
53ARAF0.98022225
54FER0.96259981
55SGK2230.96057570
56SGK4940.96057570
57PLK30.95884784
58CAMKK10.95438402
59FGR0.94543455
60STK380.93870795
61BMPR1B0.93714106
62SGK20.88248842
63CAMK10.87702500
64PLK40.86627909
65CSNK1G30.86256072
66SGK10.84595888
67CAMK2D0.82467048
68MAP3K20.82286171
69ACVR1B0.82085579
70CSNK1A1L0.80189227
71CAMKK20.79639773
72BUB10.76885209
73DYRK1A0.76809422
74BRD40.76103541
75PRKCE0.75992650
76INSRR0.72866919
77SIK30.72126627
78UHMK10.71343172
79STK38L0.69149017
80ERBB30.65700729
81TYRO30.65421892
82CSNK1G20.65333509
83MAP3K60.65294813
84BCR0.63543754
85NEK60.63374744
86CDC70.63359808
87CDK180.62945752
88CAMK2G0.61603154
89EPHB20.60968300
90CAMK1D0.59644713
91MAP3K70.59345808
92CDK150.58960001
93YES10.57776632
94CSNK1A10.56758983
95CDK140.56525814
96LATS10.56238690
97CSNK1E0.55551356
98RAF10.55382555
99TTK0.55355987
100STK110.54763119
101GRK70.54445863
102CSNK1D0.53786372
103SGK30.53207934
104BRAF0.52127524
105CDC42BPA0.51498268
106CDK30.50315999
107CDK11A0.50314550
108PAK30.49332139
109STK390.49307163
110ROCK10.49299459
111PINK10.48422312
112PLK10.48411346
113SRPK10.47196050
114PRKDC0.46173206
115ZAK0.44995888
116PRKCH0.42953384
117PHKG20.42003300
118PHKG10.42003300
119TNK20.41444079
120RPS6KA30.40625311
121ATM0.40376666
122CAMK40.38719723
123TSSK60.38224285
124WNK10.38129510
125MUSK0.37144644
126PRKACA0.37110874
127PDPK10.36939108
128FYN0.36572514
129GSK3B0.36530348
130GRK10.36102226
131FGFR10.36037410
132PRKG10.35764507
133ROCK20.35702079
134RET0.35534771
135PRKCZ0.35232259
136PKN10.34934143
137MAPK100.34909967
138PRKD20.34750024
139MAP3K10.34016565
140DMPK0.33101641
141PRKCQ0.32826283
142PRKCB0.32465471

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.47340754
2Circadian entrainment_Homo sapiens_hsa047133.06389912
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.03369298
4Long-term potentiation_Homo sapiens_hsa047203.03186970
5Glutamatergic synapse_Homo sapiens_hsa047243.00947635
6Amphetamine addiction_Homo sapiens_hsa050312.87823233
7GABAergic synapse_Homo sapiens_hsa047272.70949672
8Morphine addiction_Homo sapiens_hsa050322.70443580
9Synaptic vesicle cycle_Homo sapiens_hsa047212.60922061
10Olfactory transduction_Homo sapiens_hsa047402.45096006
11Dopaminergic synapse_Homo sapiens_hsa047282.25922451
12Salivary secretion_Homo sapiens_hsa049702.22214106
13Taste transduction_Homo sapiens_hsa047422.19500991
14Insulin secretion_Homo sapiens_hsa049112.00744751
15Serotonergic synapse_Homo sapiens_hsa047261.97681389
16Long-term depression_Homo sapiens_hsa047301.93050533
17Calcium signaling pathway_Homo sapiens_hsa040201.90921235
18Renin secretion_Homo sapiens_hsa049241.87349642
19Cocaine addiction_Homo sapiens_hsa050301.85851911
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.85734960
21Cholinergic synapse_Homo sapiens_hsa047251.81300809
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.72457814
23Oxytocin signaling pathway_Homo sapiens_hsa049211.71926248
24Gastric acid secretion_Homo sapiens_hsa049711.68533194
25Collecting duct acid secretion_Homo sapiens_hsa049661.57102397
26Non-homologous end-joining_Homo sapiens_hsa034501.52676770
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.52425310
28Axon guidance_Homo sapiens_hsa043601.51873545
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.47929137
30cAMP signaling pathway_Homo sapiens_hsa040241.47386926
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39987269
32GnRH signaling pathway_Homo sapiens_hsa049121.35940150
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.27964405
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.21006652
35Gap junction_Homo sapiens_hsa045401.18333381
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17040458
37Phototransduction_Homo sapiens_hsa047441.13530815
38Steroid biosynthesis_Homo sapiens_hsa001001.09667419
39Basal transcription factors_Homo sapiens_hsa030221.07458383
40Type II diabetes mellitus_Homo sapiens_hsa049301.07320059
41cGMP-PKG signaling pathway_Homo sapiens_hsa040221.07001936
42Vascular smooth muscle contraction_Homo sapiens_hsa042701.04734208
43Melanogenesis_Homo sapiens_hsa049161.02694968
44Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.02300638
45Propanoate metabolism_Homo sapiens_hsa006401.02205802
46Estrogen signaling pathway_Homo sapiens_hsa049151.01575021
47Pancreatic secretion_Homo sapiens_hsa049720.98948813
48Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.98582057
49Vibrio cholerae infection_Homo sapiens_hsa051100.97629315
50ErbB signaling pathway_Homo sapiens_hsa040120.96693059
51Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.96253205
52Nitrogen metabolism_Homo sapiens_hsa009100.94212960
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.94175696
54Hedgehog signaling pathway_Homo sapiens_hsa043400.93214692
55Circadian rhythm_Homo sapiens_hsa047100.90992258
56Butanoate metabolism_Homo sapiens_hsa006500.89080897
57Glioma_Homo sapiens_hsa052140.87045430
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86517306
59Choline metabolism in cancer_Homo sapiens_hsa052310.85400992
60Tight junction_Homo sapiens_hsa045300.83094475
61Fanconi anemia pathway_Homo sapiens_hsa034600.81523956
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.80221580
63Cardiac muscle contraction_Homo sapiens_hsa042600.79927741
64Hippo signaling pathway_Homo sapiens_hsa043900.79709866
65Vitamin B6 metabolism_Homo sapiens_hsa007500.79480735
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74491941
67Dilated cardiomyopathy_Homo sapiens_hsa054140.72802959
68Histidine metabolism_Homo sapiens_hsa003400.71646692
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.71135472
70Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70802149
71MAPK signaling pathway_Homo sapiens_hsa040100.69991656
72beta-Alanine metabolism_Homo sapiens_hsa004100.68842217
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68583739
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.67941505
75Basal cell carcinoma_Homo sapiens_hsa052170.66350164
76Ras signaling pathway_Homo sapiens_hsa040140.66342558
77Thyroid hormone synthesis_Homo sapiens_hsa049180.66187654
78RNA polymerase_Homo sapiens_hsa030200.66030870
79Dorso-ventral axis formation_Homo sapiens_hsa043200.62420132
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.61738545
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61393664
82Oocyte meiosis_Homo sapiens_hsa041140.61095847
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59211999
84Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58213755
85Rap1 signaling pathway_Homo sapiens_hsa040150.56828021
86VEGF signaling pathway_Homo sapiens_hsa043700.56304345
87Wnt signaling pathway_Homo sapiens_hsa043100.56066443
88Folate biosynthesis_Homo sapiens_hsa007900.55807713
89Lysine degradation_Homo sapiens_hsa003100.54809983
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54640560
91Inositol phosphate metabolism_Homo sapiens_hsa005620.52645192
92African trypanosomiasis_Homo sapiens_hsa051430.51756081
93Adherens junction_Homo sapiens_hsa045200.51442663
94Glucagon signaling pathway_Homo sapiens_hsa049220.51364498
95Alzheimers disease_Homo sapiens_hsa050100.51049749
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50751929
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50147721
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.49651107
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48921522
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48463128
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46835258
102Ovarian steroidogenesis_Homo sapiens_hsa049130.45021571
103Alcoholism_Homo sapiens_hsa050340.43622938
104Arginine and proline metabolism_Homo sapiens_hsa003300.42853822
105Sphingolipid metabolism_Homo sapiens_hsa006000.41837504
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40356602
107Regulation of autophagy_Homo sapiens_hsa041400.39195379
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37872880
109RNA degradation_Homo sapiens_hsa030180.37317271
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.37315796
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37116838
112ABC transporters_Homo sapiens_hsa020100.36624620
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36091210
114Mineral absorption_Homo sapiens_hsa049780.34872021
115mRNA surveillance pathway_Homo sapiens_hsa030150.34572006
116Glycerolipid metabolism_Homo sapiens_hsa005610.33963236
117Type I diabetes mellitus_Homo sapiens_hsa049400.33883994
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32772611
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.30712173
120Glycerophospholipid metabolism_Homo sapiens_hsa005640.30544490
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29247783
122Bile secretion_Homo sapiens_hsa049760.28311379
123Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27237586
124Rheumatoid arthritis_Homo sapiens_hsa053230.26475331
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.25182219
126Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24525719
127Prion diseases_Homo sapiens_hsa050200.23899170
128Chemokine signaling pathway_Homo sapiens_hsa040620.20889020
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.19923861
130Renal cell carcinoma_Homo sapiens_hsa052110.18471793
131Endocytosis_Homo sapiens_hsa041440.17668617
132Ether lipid metabolism_Homo sapiens_hsa005650.17444086
133Oxidative phosphorylation_Homo sapiens_hsa001900.16826252
134Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.14757247
135Non-small cell lung cancer_Homo sapiens_hsa052230.14064666

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