CTDNEP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)4.21152744
2positive regulation of histone deacetylation (GO:0031065)4.05116793
3negative regulation of fatty acid transport (GO:2000192)3.90655765
4negative regulation of cell size (GO:0045792)3.79355495
5sarcomere organization (GO:0045214)3.78897210
6muscle filament sliding (GO:0030049)3.71213104
7actin-myosin filament sliding (GO:0033275)3.71213104
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.46736137
9antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.46736137
10maternal placenta development (GO:0001893)3.43056006
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.38688582
12negative regulation of cell killing (GO:0031342)3.38688582
13barbed-end actin filament capping (GO:0051016)3.37296826
14negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.29525080
15modulation by symbiont of host cellular process (GO:0044068)3.23170556
16negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.22914642
17negative regulation of heart growth (GO:0061117)3.17508679
18negative regulation of cardiac muscle tissue growth (GO:0055022)3.17508679
19negative regulation of necroptotic process (GO:0060546)3.14467388
20modulation by virus of host process (GO:0019054)3.14424100
21antigen processing and presentation of endogenous antigen (GO:0019883)3.12423401
22positive regulation of lamellipodium assembly (GO:0010592)3.09706533
23apoptotic cell clearance (GO:0043277)3.07416038
24regulation of skeletal muscle contraction (GO:0014819)3.07338707
25regulation of interleukin-12 biosynthetic process (GO:0045075)3.04656938
26response to peptidoglycan (GO:0032494)3.00614579
27positive regulation of protein deacetylation (GO:0090312)2.99833308
28positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.99602498
29stress fiber assembly (GO:0043149)2.95428462
30ribosomal small subunit biogenesis (GO:0042274)2.93809534
31positive regulation of myotube differentiation (GO:0010831)2.89377720
32mannose metabolic process (GO:0006013)2.89328701
33negative regulation of potassium ion transmembrane transport (GO:1901380)2.88351203
34cardiac myofibril assembly (GO:0055003)2.88071363
35regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.87825926
36T cell apoptotic process (GO:0070231)2.87578798
37regulation of cholesterol storage (GO:0010885)2.82284442
38actin-mediated cell contraction (GO:0070252)2.81149206
39cellular response to zinc ion (GO:0071294)2.79630910
40regulation of mammary gland epithelial cell proliferation (GO:0033599)2.78726648
41regulation of early endosome to late endosome transport (GO:2000641)2.77920012
42apoptotic process involved in morphogenesis (GO:0060561)2.76925645
43positive regulation of Cdc42 GTPase activity (GO:0043089)2.76714971
44myofibril assembly (GO:0030239)2.76144309
45modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.75245313
46modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.75245313
47positive regulation by organism of defense response of other organism involved in symbiotic interact2.75245313
48modulation by symbiont of host immune response (GO:0052553)2.75245313
49positive regulation by symbiont of host defense response (GO:0052509)2.75245313
50modulation by symbiont of host defense response (GO:0052031)2.75245313
51regulation of necrotic cell death (GO:0010939)2.74176236
52negative regulation of erythrocyte differentiation (GO:0045647)2.73722096
53protein localization to endosome (GO:0036010)2.73683613
543-UTR-mediated mRNA stabilization (GO:0070935)2.73538740
55regulation of gamma-delta T cell differentiation (GO:0045586)2.73365635
56regulation of fatty acid beta-oxidation (GO:0031998)2.71494019
57sarcoplasmic reticulum calcium ion transport (GO:0070296)2.70714559
58positive regulation of lamellipodium organization (GO:1902745)2.70147733
59regulation of necroptotic process (GO:0060544)2.68986781
60positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.68962851
61cell-substrate junction assembly (GO:0007044)2.66170317
62modulation by virus of host morphology or physiology (GO:0019048)2.65762481
63regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.64014622
644-hydroxyproline metabolic process (GO:0019471)2.62210650
65activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.61091911
66focal adhesion assembly (GO:0048041)2.60635876
67cell-substrate adherens junction assembly (GO:0007045)2.60635876
68adherens junction assembly (GO:0034333)2.60284941
69positive regulation of gamma-delta T cell activation (GO:0046645)2.59195876
70detection of bacterium (GO:0016045)2.59149293
71response to laminar fluid shear stress (GO:0034616)2.58236082
72negative regulation of necrotic cell death (GO:0060547)2.57532542
73endothelial tube morphogenesis (GO:0061154)2.57500918
74morphogenesis of an endothelium (GO:0003159)2.57500918
75actin filament-based movement (GO:0030048)2.57201703
76regulation of leukocyte degranulation (GO:0043300)2.56116556
77regulation of extracellular matrix disassembly (GO:0010715)2.55296188
78positive regulation of nuclease activity (GO:0032075)2.55171288
79carnitine shuttle (GO:0006853)2.53974995
80protein retention in ER lumen (GO:0006621)2.53902390
81NADH metabolic process (GO:0006734)2.53367405
82regulation of p38MAPK cascade (GO:1900744)2.53137954
83detection of other organism (GO:0098543)2.53110181
84low-density lipoprotein particle clearance (GO:0034383)2.52434886
85JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.52183726
86regulation of integrin activation (GO:0033623)2.51876069
87cytidine metabolic process (GO:0046087)2.51392688
88cytidine catabolic process (GO:0006216)2.51392688
89cytidine deamination (GO:0009972)2.51392688
90intracellular estrogen receptor signaling pathway (GO:0030520)2.51023894
91growth hormone receptor signaling pathway (GO:0060396)2.49383633
92positive regulation of lipid storage (GO:0010884)2.49347220
93macrophage activation involved in immune response (GO:0002281)2.49011861
94skin morphogenesis (GO:0043589)2.48637017
95positive thymic T cell selection (GO:0045059)2.47888893
96positive regulation of protein dephosphorylation (GO:0035307)2.47653872
97regulation of gamma-delta T cell activation (GO:0046643)2.47489948
98natural killer cell differentiation (GO:0001779)2.46891372
99lymphocyte apoptotic process (GO:0070227)2.46224442
100NIK/NF-kappaB signaling (GO:0038061)2.45056188
101negative regulation of nucleotide catabolic process (GO:0030812)2.44552901
102Arp2/3 complex-mediated actin nucleation (GO:0034314)2.44477411
103pentose-phosphate shunt (GO:0006098)2.44474505
104RNA stabilization (GO:0043489)2.43972380
105mRNA stabilization (GO:0048255)2.43972380
106cortical actin cytoskeleton organization (GO:0030866)2.43762926
107viral transcription (GO:0019083)2.42974449
108regulation of interferon-beta biosynthetic process (GO:0045357)2.42862942
109response to muramyl dipeptide (GO:0032495)2.42466269
110lipopolysaccharide-mediated signaling pathway (GO:0031663)2.42346068
111regulation of NFAT protein import into nucleus (GO:0051532)2.42270325
112response to parathyroid hormone (GO:0071107)2.41972576
113germinal center formation (GO:0002467)2.41292140
114regulation of defense response to virus by virus (GO:0050690)2.41014847
115positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.40740669
116pinocytosis (GO:0006907)2.40735884
117actomyosin structure organization (GO:0031032)2.40008303
118positive regulation of fatty acid beta-oxidation (GO:0032000)2.39892306
119skeletal muscle adaptation (GO:0043501)2.39838102
120basement membrane organization (GO:0071711)2.39495919
121pyrimidine ribonucleoside catabolic process (GO:0046133)2.39341466
122positive regulation of blood vessel endothelial cell migration (GO:0043536)2.39166393
123maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.38774458
124cell-cell junction maintenance (GO:0045217)2.38695311
125negative regulation of homotypic cell-cell adhesion (GO:0034111)2.37600706
126epithelial cell-cell adhesion (GO:0090136)2.37371378
127cellular response to virus (GO:0098586)2.37150121
128fatty acid transmembrane transport (GO:1902001)2.37074164
129heterochromatin organization (GO:0070828)2.36609921
130regulation of response to osmotic stress (GO:0047484)2.36525911
131regulation of myeloid leukocyte mediated immunity (GO:0002886)2.36224174
132signal complex assembly (GO:0007172)2.35790102
133activation of MAPKKK activity (GO:0000185)2.35109366
134negative regulation of toll-like receptor signaling pathway (GO:0034122)2.34811175
135regulation of fatty acid oxidation (GO:0046320)2.34696797
136endothelial cell chemotaxis (GO:0035767)2.33332932
137NLS-bearing protein import into nucleus (GO:0006607)2.32814533
138creatine metabolic process (GO:0006600)2.32803607
139tooth mineralization (GO:0034505)2.32563465
140neutrophil activation involved in immune response (GO:0002283)2.31532569
141response to host (GO:0075136)2.31520654
142response to host defenses (GO:0052200)2.31520654
143response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.31520654
144negative regulation of skeletal muscle tissue development (GO:0048642)2.31334456
145positive regulation of extracellular matrix organization (GO:1903055)2.31105615
146regulation of nuclease activity (GO:0032069)2.30788905
147negative regulation of phagocytosis (GO:0050765)2.29450835
148regulation of T-helper 2 cell differentiation (GO:0045628)2.29390179
149regulation of cholesterol homeostasis (GO:2000188)2.29360077
150skeletal muscle contraction (GO:0003009)2.28651975
151regulation of superoxide anion generation (GO:0032928)2.28430329
152negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.28289495
153cardiac muscle contraction (GO:0060048)2.28208930
154leukocyte aggregation (GO:0070486)2.27183425
155peptidyl-lysine dimethylation (GO:0018027)2.26909910
156regulation of mast cell degranulation (GO:0043304)2.25600914
157positive regulation of protein export from nucleus (GO:0046827)2.24604737
158vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.23837259
159positive regulation of receptor recycling (GO:0001921)2.23748205
160embryonic process involved in female pregnancy (GO:0060136)2.22552227
161negative regulation of interleukin-12 production (GO:0032695)2.22448150
162regulation of chromatin binding (GO:0035561)2.22146827

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.23372791
2MYC_22102868_ChIP-Seq_BL_Human3.07091884
3EGR1_19374776_ChIP-ChIP_THP-1_Human2.86397864
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.75649140
5VDR_21846776_ChIP-Seq_THP-1_Human2.74046412
6ELK3_25401928_ChIP-Seq_HUVEC_Human2.40976018
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.35059744
8RARG_19884340_ChIP-ChIP_MEFs_Mouse2.34302414
9LXR_22292898_ChIP-Seq_THP-1_Human2.33536347
10TCF7_22412390_ChIP-Seq_EML_Mouse2.33290507
11KDM2B_26808549_Chip-Seq_DND41_Human2.30618623
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.28610085
13KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.08779201
14TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05649472
15THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.03001605
16MAF_26560356_Chip-Seq_TH1_Human2.01612995
17STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.95827768
18BP1_19119308_ChIP-ChIP_Hs578T_Human1.95439774
19RACK7_27058665_Chip-Seq_MCF-7_Human1.94496622
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.92065004
21KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.90346151
22EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.89903518
23ZNF263_19887448_ChIP-Seq_K562_Human1.81691520
24KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.76118804
25VDR_24763502_ChIP-Seq_THP-1_Human1.75311280
26UTX_26944678_Chip-Seq_JUKART_Human1.71293593
27TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.70462808
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.69798292
29BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69218724
30IRF8_22096565_ChIP-ChIP_GC-B_Human1.68952094
31RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.67075171
32TET1_21451524_ChIP-Seq_MESCs_Mouse1.66535984
33TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.64855435
34FOXM1_23109430_ChIP-Seq_U2OS_Human1.60717758
35CLOCK_20551151_ChIP-Seq_293T_Human1.60258243
36PPARA_22158963_ChIP-Seq_LIVER_Mouse1.59747164
37STAT6_21828071_ChIP-Seq_BEAS2B_Human1.57852688
38E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.57001801
39NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56352317
40ATF3_27146783_Chip-Seq_COLON_Human1.54371127
41P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50757801
42SRY_22984422_ChIP-ChIP_TESTIS_Rat1.50349475
43ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.46452875
44MYB_21317192_ChIP-Seq_ERMYB_Mouse1.44844823
45KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.44355641
46RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.43617551
47MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.43471505
48KDM2B_26808549_Chip-Seq_JURKAT_Human1.43397325
49ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42820415
50NCOR1_26117541_ChIP-Seq_K562_Human1.39812694
51MAF_26560356_Chip-Seq_TH2_Human1.39425421
52SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39264653
53ERG_21242973_ChIP-ChIP_JURKAT_Human1.35451163
54TRIM28_21343339_ChIP-Seq_HEK293_Human1.34819124
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34636758
56SMC4_20622854_ChIP-Seq_HELA_Human1.30522375
57SPI1_23127762_ChIP-Seq_K562_Human1.29714570
58KDM2B_26808549_Chip-Seq_K562_Human1.29452154
59RXR_22158963_ChIP-Seq_LIVER_Mouse1.29045296
60TBX20_22080862_ChIP-Seq_HEART_Mouse1.28922116
61TBX20_22328084_ChIP-Seq_HEART_Mouse1.28922116
62UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28634992
63DNAJC2_21179169_ChIP-ChIP_NT2_Human1.28085068
64PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26091857
65RUNX1_22412390_ChIP-Seq_EML_Mouse1.25258529
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.25176319
67CTCF_27219007_Chip-Seq_ERYTHROID_Human1.24554574
68IRF8_27001747_Chip-Seq_BMDM_Mouse1.23915160
69IRF8_21731497_ChIP-ChIP_J774_Mouse1.20473033
70P68_20966046_ChIP-Seq_HELA_Human1.20301804
71SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.19791520
72ELF1_20517297_ChIP-Seq_JURKAT_Human1.18930954
73ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.18449877
74CREB1_26743006_Chip-Seq_LNCaP_Human1.18328102
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17718994
76STAT3_1855785_ChIP-Seq_MESCs_Mouse1.17700072
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17090164
78RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15432096
79HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.15237769
80FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.14889536
81TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.14872172
82BCOR_27268052_Chip-Seq_Bcells_Human1.14823761
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14619601
84GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13409402
85SCL_19346495_ChIP-Seq_HPC-7_Human1.12596764
86SA1_27219007_Chip-Seq_ERYTHROID_Human1.11860821
87CTCF_21964334_ChIP-Seq_BJAB-B_Human1.11708490
88ZFP281_27345836_Chip-Seq_ESCs_Mouse1.10236833
89MYB_26560356_Chip-Seq_TH2_Human1.10025023
90CTCF_21964334_Chip-Seq_Bcells_Human1.09875885
91TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09740652
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.09704912
93BCL6_27268052_Chip-Seq_Bcells_Human1.09644948
94CTCF_26484167_Chip-Seq_Bcells_Mouse1.09523692
95PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09453720
96CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08710105
97KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08048553
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07439937
99HIF1A_21447827_ChIP-Seq_MCF-7_Human1.06903425
100ESR2_21235772_ChIP-Seq_MCF-7_Human1.06560751
101MYB_26560356_Chip-Seq_TH1_Human1.06056773
102VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.05830078
103CTCF_27219007_Chip-Seq_Bcells_Human1.05302788
104WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04230189
105SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.04225183
106ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03499225
107CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02976431
108ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02686815
109IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02363496
110SMC1_22415368_ChIP-Seq_MEFs_Mouse1.02353421
111TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02249406
112EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.01788119
113MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00648410
114GATA1_19941826_ChIP-Seq_K562_Human1.00544448
115CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.00412626
116LXR_22158963_ChIP-Seq_LIVER_Mouse1.00337804
117GATA1_19941827_ChIP-Seq_MEL_Mouse0.99650588
118STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.99544220
119SA1_27219007_Chip-Seq_Bcells_Human0.99418017
120MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.99314955
121SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98406273
122TP53_22127205_ChIP-Seq_IMR90_Human0.98097207
123GATA6_25053715_ChIP-Seq_YYC3_Human0.98078951
124NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97206830
125EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.94503060
126EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92798229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition3.85941480
2MP0003705_abnormal_hypodermis_morpholog3.78983562
3MP0003303_peritoneal_inflammation2.87615590
4MP0003300_gastrointestinal_ulcer2.49538119
5MP0005076_abnormal_cell_differentiation2.39685969
6MP0009278_abnormal_bone_marrow2.27814503
7MP0004858_abnormal_nervous_system2.26531491
8MP0000751_myopathy2.23886574
9MP0003646_muscle_fatigue2.13098355
10MP0004510_myositis2.07532865
11MP0004185_abnormal_adipocyte_glucose2.05506800
12MP0008260_abnormal_autophagy2.05062909
13MP0004087_abnormal_muscle_fiber2.02722238
14MP0010352_gastrointestinal_tract_polyps2.01878638
15MP0008438_abnormal_cutaneous_collagen2.01401331
16MP0003566_abnormal_cell_adhesion1.98343094
17MP0000750_abnormal_muscle_regeneration1.94128423
18MP0000733_abnormal_muscle_development1.91397037
19MP0000749_muscle_degeneration1.90787278
20MP0002877_abnormal_melanocyte_morpholog1.89189517
21MP0004130_abnormal_muscle_cell1.88117963
22MP0002837_dystrophic_cardiac_calcinosis1.79619041
23MP0000678_abnormal_parathyroid_gland1.78049400
24MP0004084_abnormal_cardiac_muscle1.77649718
25MP0003436_decreased_susceptibility_to1.74289159
26MP0009840_abnormal_foam_cell1.69615877
27MP0010630_abnormal_cardiac_muscle1.65029991
28MP0000685_abnormal_immune_system1.63035013
29MP0002106_abnormal_muscle_physiology1.60931789
30MP0005409_darkened_coat_color1.50719317
31MP0005058_abnormal_lysosome_morphology1.49232481
32MP0000759_abnormal_skeletal_muscle1.48801463
33MP0005330_cardiomyopathy1.46885935
34MP0008961_abnormal_basal_metabolism1.46737523
35MP0005666_abnormal_adipose_tissue1.46187225
36MP0002269_muscular_atrophy1.45105592
37MP0003279_aneurysm1.39851513
38MP0003828_pulmonary_edema1.39381264
39MP0004036_abnormal_muscle_relaxation1.37021674
40MP0009379_abnormal_foot_pigmentation1.32867896
41MP0000747_muscle_weakness1.32446230
42MP0001849_ear_inflammation1.30222301
43MP0001835_abnormal_antigen_presentation1.26230167
44MP0002998_abnormal_bone_remodeling1.25879055
45MP0005397_hematopoietic_system_phenotyp1.25844035
46MP0001545_abnormal_hematopoietic_system1.25844035
47MP0000343_altered_response_to1.25241691
48MP0002249_abnormal_larynx_morphology1.24582281
49MP0005375_adipose_tissue_phenotype1.23426481
50MP0005369_muscle_phenotype1.23419051
51MP0005387_immune_system_phenotype1.22948475
52MP0001790_abnormal_immune_system1.22948475
53MP0005023_abnormal_wound_healing1.22711980
54MP0003763_abnormal_thymus_physiology1.20780095
55MP0003191_abnormal_cellular_cholesterol1.18043410
56MP0003329_amyloid_beta_deposits1.14545465
57MP0006054_spinal_hemorrhage1.14147878
58MP0001958_emphysema1.13804032
59MP0005275_abnormal_skin_tensile1.12431061
60MP0004233_abnormal_muscle_weight1.11502124
61MP0009333_abnormal_splenocyte_physiolog1.11360429
62MP0004145_abnormal_muscle_electrophysio1.11318023
63MP0010368_abnormal_lymphatic_system1.10347749
64MP0002796_impaired_skin_barrier1.09593285
65MP0004808_abnormal_hematopoietic_stem1.09218433
66MP0001544_abnormal_cardiovascular_syste1.09114474
67MP0005385_cardiovascular_system_phenoty1.09114474
68MP0006082_CNS_inflammation1.07877486
69MP0005623_abnormal_meninges_morphology1.06600848
70MP0004947_skin_inflammation1.04028452
71MP0001348_abnormal_lacrimal_gland1.03949531
72MP0002405_respiratory_system_inflammati1.03893053
73MP0001873_stomach_inflammation1.03091623
74MP0003075_altered_response_to1.02506326
75MP0010155_abnormal_intestine_physiology1.01784781
76MP0005166_decreased_susceptibility_to1.01112047
77MP0010030_abnormal_orbit_morphology1.00673510
78MP0003567_abnormal_fetal_cardiomyocyte0.97775442
79MP0000858_altered_metastatic_potential0.97622596
80MP0002148_abnormal_hypersensitivity_rea0.97571131
81MP0003091_abnormal_cell_migration0.97428208
82MP0000767_abnormal_smooth_muscle0.96702117
83MP0001533_abnormal_skeleton_physiology0.96331146
84MP0005000_abnormal_immune_tolerance0.96129229
85MP0000681_abnormal_thyroid_gland0.95539609
86MP0005464_abnormal_platelet_physiology0.95408758
87MP0003448_altered_tumor_morphology0.92627318
88MP0002452_abnormal_antigen_presenting0.92341963
89MP0001800_abnormal_humoral_immune0.92128344
90MP0003724_increased_susceptibility_to0.91778159
91MP0003221_abnormal_cardiomyocyte_apopto0.90756667
92MP0005620_abnormal_muscle_contractility0.90367010
93MP0006138_congestive_heart_failure0.88246435
94MP0000703_abnormal_thymus_morphology0.87675776
95MP0000003_abnormal_adipose_tissue0.87617542
96MP0002972_abnormal_cardiac_muscle0.87134130
97MP0005025_abnormal_response_to0.87011039
98MP0005390_skeleton_phenotype0.85965314
99MP0003453_abnormal_keratinocyte_physiol0.85750673
100MP0000266_abnormal_heart_morphology0.85518080
101MP0009785_altered_susceptibility_to0.85499514
102MP0000716_abnormal_immune_system0.85483330
103MP0000490_abnormal_crypts_of0.85480681
104MP0008775_abnormal_heart_ventricle0.84655461
105MP0002332_abnormal_exercise_endurance0.84588110
106MP0010307_abnormal_tumor_latency0.83237936
107MP0002166_altered_tumor_susceptibility0.83177817
108MP0002419_abnormal_innate_immunity0.81872615
109MP0009115_abnormal_fat_cell0.81821380
110MP0005501_abnormal_skin_physiology0.80864473
111MP0002398_abnormal_bone_marrow0.80256732
112MP0003172_abnormal_lysosome_physiology0.79428278
113MP0000604_amyloidosis0.78641260
114MP0001819_abnormal_immune_cell0.77758064
115MP0002429_abnormal_blood_cell0.77695921
116MP0002420_abnormal_adaptive_immunity0.77101767
117MP0002128_abnormal_blood_circulation0.76964421
118MP0002396_abnormal_hematopoietic_system0.76896019
119MP0005083_abnormal_biliary_tract0.76862712
120MP0002925_abnormal_cardiovascular_devel0.76765069
121MP0002138_abnormal_hepatobiliary_system0.76733182
122MP0002089_abnormal_postnatal_growth/wei0.76136012
123MP0001879_abnormal_lymphatic_vessel0.75855194
124MP0005257_abnormal_intraocular_pressure0.75653951
125MP0002722_abnormal_immune_system0.75085783
126MP0002971_abnormal_brown_adipose0.74796147
127MP0003984_embryonic_growth_retardation0.73998324
128MP0002723_abnormal_immune_serum0.73792029

Predicted human phenotypes

RankGene SetZ-score
1Centrally nucleated skeletal muscle fibers (HP:0003687)3.93051606
2Exercise-induced muscle cramps (HP:0003710)3.91015842
3Exercise-induced myalgia (HP:0003738)3.75560633
4Type 1 muscle fiber predominance (HP:0003803)3.73597713
5Increased connective tissue (HP:0009025)3.64463492
6Asymmetric septal hypertrophy (HP:0001670)3.47857757
7Muscle fiber inclusion bodies (HP:0100299)3.37068487
8Cerebral aneurysm (HP:0004944)3.26684138
9Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.24780146
10Muscle fiber splitting (HP:0003555)3.20058421
11Protrusio acetabuli (HP:0003179)3.16820828
12Distal lower limb muscle weakness (HP:0009053)3.12730650
13Difficulty running (HP:0009046)3.12582521
14Ventricular tachycardia (HP:0004756)3.11456333
15Myoglobinuria (HP:0002913)3.10901434
16Ulnar deviation of the wrist (HP:0003049)3.07157677
17Difficulty climbing stairs (HP:0003551)2.97467080
18Sudden death (HP:0001699)2.95227507
19Hyporeflexia of lower limbs (HP:0002600)2.92176503
20Subaortic stenosis (HP:0001682)2.83745701
21Abnormality of the left ventricular outflow tract (HP:0011103)2.83745701
22Myopathic facies (HP:0002058)2.80008925
23Vertebral compression fractures (HP:0002953)2.68869681
24Nemaline bodies (HP:0003798)2.68305570
25Bulbar palsy (HP:0001283)2.66994147
26Obstructive sleep apnea (HP:0002870)2.64481629
27Frequent falls (HP:0002359)2.62950341
28Abnormality of skeletal muscle fiber size (HP:0012084)2.56571428
29Eczematoid dermatitis (HP:0000976)2.51379099
30Calf muscle hypertrophy (HP:0008981)2.50777708
31Right ventricular cardiomyopathy (HP:0011663)2.49172154
32Rhabdomyolysis (HP:0003201)2.46887362
33EMG: myopathic abnormalities (HP:0003458)2.45311513
34Achilles tendon contracture (HP:0001771)2.44992680
35Increased variability in muscle fiber diameter (HP:0003557)2.44229886
36Round ear (HP:0100830)2.43050620
37Increased density of long bones (HP:0006392)2.43042364
38Polycythemia (HP:0001901)2.42709774
39Muscle hypertrophy of the lower extremities (HP:0008968)2.39404285
40Premature rupture of membranes (HP:0001788)2.36912812
41Shallow orbits (HP:0000586)2.35296597
42Mildly elevated creatine phosphokinase (HP:0008180)2.35295582
43Abnormality of the Achilles tendon (HP:0005109)2.27795712
44Distal arthrogryposis (HP:0005684)2.26377058
45Broad metatarsal (HP:0001783)2.24934070
46Upper limb amyotrophy (HP:0009129)2.21315651
47Distal upper limb amyotrophy (HP:0007149)2.21315651
48Muscle stiffness (HP:0003552)2.20633928
49Rectal prolapse (HP:0002035)2.15921583
50Abnormality of macrophages (HP:0004311)2.14702849
51Peritonitis (HP:0002586)2.14433311
52Abnormality of the calf musculature (HP:0001430)2.14329235
53Limb-girdle muscle atrophy (HP:0003797)2.13827679
54Interstitial pulmonary disease (HP:0006530)2.13183780
55Mitral valve prolapse (HP:0001634)2.10799291
56Increased cerebral lipofuscin (HP:0011813)2.07974108
57Recurrent bacterial skin infections (HP:0005406)2.05755718
58Aneurysm (HP:0002617)2.05361717
59Obstructive lung disease (HP:0006536)2.05208078
60Chronic obstructive pulmonary disease (HP:0006510)2.05208078
61Slender build (HP:0001533)2.04689425
62Lipoatrophy (HP:0100578)2.04555961
63Ulnar bowing (HP:0003031)2.04499933
64Spontaneous hematomas (HP:0007420)2.04210135
65Progressive muscle weakness (HP:0003323)2.02394746
66Axonal loss (HP:0003447)2.01305566
67Foot dorsiflexor weakness (HP:0009027)1.99112207
68Lymphangioma (HP:0100764)1.98967642
69Fragile skin (HP:0001030)1.98826270
70Urinary glycosaminoglycan excretion (HP:0003541)1.96593935
71Mucopolysacchariduria (HP:0008155)1.96593935
72Ragged-red muscle fibers (HP:0003200)1.96503992
73Hyperacusis (HP:0010780)1.96409882
74Increased IgE level (HP:0003212)1.96356747
75Abnormality of the nasal mucosa (HP:0000433)1.95038509
76Cervical subluxation (HP:0003308)1.95034658
77Conjunctival hamartoma (HP:0100780)1.93802245
78Cellulitis (HP:0100658)1.93183517
79Bundle branch block (HP:0011710)1.92457272
80Scapular winging (HP:0003691)1.91726001
81Polygenic inheritance (HP:0010982)1.90923045
82Easy fatigability (HP:0003388)1.87453852
83Dysostosis multiplex (HP:0000943)1.86803825
84Ankle contracture (HP:0006466)1.86251134
85Genu recurvatum (HP:0002816)1.86115311
86Gastrointestinal stroma tumor (HP:0100723)1.85961481
87Hyperparathyroidism (HP:0000843)1.85333779
88Hypertensive crisis (HP:0100735)1.85152688
89Mitral regurgitation (HP:0001653)1.84563984
90Dilatation of the ascending aorta (HP:0005111)1.83661728
91Long palpebral fissure (HP:0000637)1.83467017
92Abnormality of the thoracic spine (HP:0100711)1.82942122
93Abnormality of the foot musculature (HP:0001436)1.82793646
94Multiple enchondromatosis (HP:0005701)1.82679867
95Purpura (HP:0000979)1.81675228
96Distal lower limb amyotrophy (HP:0008944)1.81529107
97Calcaneovalgus deformity (HP:0001848)1.81393481
98Hematochezia (HP:0002573)1.80956976
99Hand muscle atrophy (HP:0009130)1.79325574
100Segmental peripheral demyelination/remyelination (HP:0003481)1.78686954
101Spinal rigidity (HP:0003306)1.76696746
102Chest pain (HP:0100749)1.76317338
103Emphysema (HP:0002097)1.75899291
104Lower limb amyotrophy (HP:0007210)1.75677120
105Myocardial infarction (HP:0001658)1.74928007
106Myotonia (HP:0002486)1.73788543
107Mesangial abnormality (HP:0001966)1.72615911
108Hamartoma of the eye (HP:0010568)1.72598381
109Generalized amyotrophy (HP:0003700)1.72218391
110Thin bony cortex (HP:0002753)1.72051342
111Atrioventricular block (HP:0001678)1.71965569
112Abnormality of glycolipid metabolism (HP:0010969)1.71805453
113Abnormality of liposaccharide metabolism (HP:0010968)1.71805453
114Abnormality of glycosphingolipid metabolism (HP:0004343)1.71805453
115Broad face (HP:0000283)1.70945829
116Deformed tarsal bones (HP:0008119)1.70598240
117Fatigue (HP:0012378)1.70520556
118Stridor (HP:0010307)1.70491689
119Recurrent abscess formation (HP:0002722)1.70401546
120Thoracic kyphosis (HP:0002942)1.70366048
121Nasal polyposis (HP:0100582)1.69130552
122Hypercortisolism (HP:0001578)1.69079081
123Aortic aneurysm (HP:0004942)1.68123626
124Gastrointestinal inflammation (HP:0004386)1.66946406
125Verrucae (HP:0200043)1.66674541
126Papilloma (HP:0012740)1.66674541
127Neck muscle weakness (HP:0000467)1.66444919
128Abnormality of mucopolysaccharide metabolism (HP:0011020)1.66260025
129Abnormality of polysaccharide metabolism (HP:0011012)1.66260025
130Abnormality of glycosaminoglycan metabolism (HP:0004371)1.66260025
131Disproportionate tall stature (HP:0001519)1.65674506
132Abnormal atrioventricular conduction (HP:0005150)1.64727024
133Abnormality of the calcaneus (HP:0008364)1.63740661
134Long toe (HP:0010511)1.63636301
135Hemorrhage of the eye (HP:0011885)1.60122328
136Myositis (HP:0100614)1.56886870
137Blue sclerae (HP:0000592)1.56170753
138Systemic lupus erythematosus (HP:0002725)1.55287228
139Supranuclear gaze palsy (HP:0000605)1.54812607
140Amyloidosis (HP:0011034)1.54720233
141Gingivitis (HP:0000230)1.54287166
142Back pain (HP:0003418)1.53364749

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.91111450
2PKN24.15721765
3PRPF4B3.63002126
4ERN13.58039503
5TTN3.48706069
6SMG13.04824537
7MAP3K102.92334177
8EEF2K2.49876831
9RIPK12.14530444
10IRAK32.13284861
11MAP4K12.11637526
12DMPK1.86082484
13RIPK41.83913482
14PTK61.82652025
15LRRK21.79857137
16MAP3K131.73714760
17ICK1.67727942
18MAP2K31.62160259
19BMX1.60083318
20TAOK11.49992792
21PDGFRA1.49657354
22ARAF1.48802999
23SIK11.45752571
24CDK121.42609052
25EPHB11.40913470
26TBK11.32126609
27TGFBR21.31774783
28MAP3K111.24410895
29IRAK41.23840172
30MAPK121.19995268
31ILK1.19474249
32PHKG11.18848080
33PHKG21.18848080
34MARK21.17735839
35OBSCN1.16038696
36MOS1.15336031
37ALK1.15050624
38CDC42BPA1.12145785
39NME21.09340622
40RPS6KA41.09277851
41MAP3K71.06595195
42ZAP701.03982457
43PDPK11.01097693
44BRAF0.99656405
45TYK20.98667810
46PAK40.98574997
47STK100.97905713
48DDR20.94955396
49FGFR40.94319055
50PRKD30.93400858
51PIM20.93358868
52GRK60.92000553
53NEK10.91733229
54JAK30.88189127
55CDK60.87807589
56BLK0.86402750
57CSK0.86205394
58MTOR0.83505684
59MAP3K30.81138781
60IRAK20.80331372
61LATS20.79409704
62PRKD20.74838572
63CDK40.74088021
64MAP3K140.73736978
65SIK30.71134863
66TYRO30.69739930
67PAK20.68351595
68CAMK1D0.67655514
69STK30.67508668
70MAP2K20.67252824
71PRKCH0.67109635
72DYRK1B0.66620672
73PDK10.66087383
74PTK20.65981055
75MAPK70.64613298
76JAK20.64551308
77PRKD10.64044973
78BCKDK0.63202716
79MAP3K80.62600166
80PDGFRB0.61929153
81STK240.61895463
82BTK0.61608193
83HCK0.61413817
84CAMK1G0.61328707
85JAK10.60522878
86CDK190.60330682
87TNK20.60209535
88FES0.59909416
89MAP3K90.59565602
90SIK20.58704739
91HIPK20.57472916
92NEK20.57336773
93FLT30.57030181
94EPHB20.55246865
95PRKG20.54212367
96KDR0.54030285
97RPS6KA60.53623883
98RPS6KL10.53603605
99RPS6KC10.53603605
100RPS6KA10.53250850
101FGFR30.53002328
102KSR20.52731967
103VRK20.52328818
104SGK30.52226604
105LMTK20.51524163
106MAP3K60.51240758
107PIK3CG0.50548454
108LATS10.50395157
109PIM10.49503745
110ABL20.48108030
111TRPM70.47241104
112NEK90.45894352
113TESK10.45408828
114MAPK110.45170321
115MAP3K10.45042259
116MAPK40.44335224
117RET0.43622287
118CSF1R0.43370503
119CAMKK10.43324146
120MARK30.43306241
121TESK20.42581021
122SCYL20.42400888
123MAPKAPK20.42261013
124CHUK0.40428489
125DAPK30.38857723
126TGFBR10.37804508
127TAOK20.37554294
128RPS6KA20.37518454
129PAK10.36878676
130AKT20.35965724
131NTRK10.34088172
132CDK90.33818095
133CDK70.33303767
134FGR0.33009544

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052202.12001516
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.04675027
3Other glycan degradation_Homo sapiens_hsa005112.01068353
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.97830558
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.97700995
6Leishmaniasis_Homo sapiens_hsa051401.90808372
7Viral myocarditis_Homo sapiens_hsa054161.87486980
8Acute myeloid leukemia_Homo sapiens_hsa052211.69061061
9Insulin resistance_Homo sapiens_hsa049311.63111697
10B cell receptor signaling pathway_Homo sapiens_hsa046621.60961085
11AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.58381554
12Osteoclast differentiation_Homo sapiens_hsa043801.57174359
13Adipocytokine signaling pathway_Homo sapiens_hsa049201.54493596
14Sulfur relay system_Homo sapiens_hsa041221.52413257
15Dilated cardiomyopathy_Homo sapiens_hsa054141.52319966
16Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.52055152
17Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.49182307
18Toxoplasmosis_Homo sapiens_hsa051451.43684134
19Prion diseases_Homo sapiens_hsa050201.41824841
20Glycosaminoglycan degradation_Homo sapiens_hsa005311.41387918
21Leukocyte transendothelial migration_Homo sapiens_hsa046701.41379493
22Proteoglycans in cancer_Homo sapiens_hsa052051.40028969
23VEGF signaling pathway_Homo sapiens_hsa043701.37521171
24Focal adhesion_Homo sapiens_hsa045101.37483927
25Bladder cancer_Homo sapiens_hsa052191.36335888
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.32538907
27Fructose and mannose metabolism_Homo sapiens_hsa000511.32068962
28Notch signaling pathway_Homo sapiens_hsa043301.31251766
29Adherens junction_Homo sapiens_hsa045201.30701530
30mTOR signaling pathway_Homo sapiens_hsa041501.27419678
31Small cell lung cancer_Homo sapiens_hsa052221.25995582
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.25310130
33Non-small cell lung cancer_Homo sapiens_hsa052231.22471958
34Amoebiasis_Homo sapiens_hsa051461.22420870
35Toll-like receptor signaling pathway_Homo sapiens_hsa046201.20968669
36Insulin signaling pathway_Homo sapiens_hsa049101.20513517
37Shigellosis_Homo sapiens_hsa051311.20456614
38Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.18775240
39Pancreatic cancer_Homo sapiens_hsa052121.16443272
40Neurotrophin signaling pathway_Homo sapiens_hsa047221.14864827
41GnRH signaling pathway_Homo sapiens_hsa049121.13522615
42Central carbon metabolism in cancer_Homo sapiens_hsa052301.13380059
43Apoptosis_Homo sapiens_hsa042101.13110369
44Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12366534
45HIF-1 signaling pathway_Homo sapiens_hsa040661.11519532
46Legionellosis_Homo sapiens_hsa051341.11366813
47Tuberculosis_Homo sapiens_hsa051521.06269083
48Longevity regulating pathway - mammal_Homo sapiens_hsa042111.04499778
49Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.03956085
50Fatty acid degradation_Homo sapiens_hsa000711.03064026
51Carbon metabolism_Homo sapiens_hsa012001.01888869
52Prolactin signaling pathway_Homo sapiens_hsa049171.00211153
53Platelet activation_Homo sapiens_hsa046110.99977043
54AMPK signaling pathway_Homo sapiens_hsa041520.99961352
55Hepatitis B_Homo sapiens_hsa051610.98145822
56TNF signaling pathway_Homo sapiens_hsa046680.98042241
57Galactose metabolism_Homo sapiens_hsa000520.97378554
58Lysosome_Homo sapiens_hsa041420.97346591
59ErbB signaling pathway_Homo sapiens_hsa040120.95642535
60Pertussis_Homo sapiens_hsa051330.92787908
61Lysine degradation_Homo sapiens_hsa003100.92406073
62Staphylococcus aureus infection_Homo sapiens_hsa051500.91431229
63Glioma_Homo sapiens_hsa052140.90914695
64Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.90896078
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90427532
66Long-term potentiation_Homo sapiens_hsa047200.90080530
67Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89993974
68NF-kappa B signaling pathway_Homo sapiens_hsa040640.89444431
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.88683345
70Starch and sucrose metabolism_Homo sapiens_hsa005000.88484103
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.86569187
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86437434
73Endometrial cancer_Homo sapiens_hsa052130.85541114
74HTLV-I infection_Homo sapiens_hsa051660.83493554
75Renal cell carcinoma_Homo sapiens_hsa052110.82770073
76Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82377237
77Measles_Homo sapiens_hsa051620.82178284
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81937778
79Salmonella infection_Homo sapiens_hsa051320.81639875
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.81620979
81Thyroid cancer_Homo sapiens_hsa052160.80726385
82Antigen processing and presentation_Homo sapiens_hsa046120.79470245
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.79060137
84Chemokine signaling pathway_Homo sapiens_hsa040620.76343780
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.75130967
86Choline metabolism in cancer_Homo sapiens_hsa052310.74981303
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74765817
88Nitrogen metabolism_Homo sapiens_hsa009100.74363724
89Estrogen signaling pathway_Homo sapiens_hsa049150.74131697
90MicroRNAs in cancer_Homo sapiens_hsa052060.73961230
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73093739
92MAPK signaling pathway_Homo sapiens_hsa040100.72110151
93Influenza A_Homo sapiens_hsa051640.72045818
94PPAR signaling pathway_Homo sapiens_hsa033200.71668911
95T cell receptor signaling pathway_Homo sapiens_hsa046600.70862243
96FoxO signaling pathway_Homo sapiens_hsa040680.69547716
97Glucagon signaling pathway_Homo sapiens_hsa049220.68640365
98Biosynthesis of amino acids_Homo sapiens_hsa012300.67849278
99Pentose phosphate pathway_Homo sapiens_hsa000300.67500997
100Herpes simplex infection_Homo sapiens_hsa051680.66485439
101Endocytosis_Homo sapiens_hsa041440.65953687
102Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65939649
103Arginine biosynthesis_Homo sapiens_hsa002200.65864247
104Colorectal cancer_Homo sapiens_hsa052100.63970381
105Phagosome_Homo sapiens_hsa041450.63479601
106Ribosome_Homo sapiens_hsa030100.62986753
107ECM-receptor interaction_Homo sapiens_hsa045120.62528737
108Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.62387751
109RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.60683295
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.60000136
111Fatty acid metabolism_Homo sapiens_hsa012120.59649802
112Prostate cancer_Homo sapiens_hsa052150.58998471
113Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.58466002
114Allograft rejection_Homo sapiens_hsa053300.57472247
115Vibrio cholerae infection_Homo sapiens_hsa051100.57020808
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56885832
117Malaria_Homo sapiens_hsa051440.53960324
118Cyanoamino acid metabolism_Homo sapiens_hsa004600.53936276
119Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53925089
120Epstein-Barr virus infection_Homo sapiens_hsa051690.53719652
121Type II diabetes mellitus_Homo sapiens_hsa049300.53463933
122Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.52087115
123Primary immunodeficiency_Homo sapiens_hsa053400.50770521
124Hepatitis C_Homo sapiens_hsa051600.50589561
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.49158073

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