CSDC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.61527658
2vocalization behavior (GO:0071625)5.39431124
3regulation of actin filament-based movement (GO:1903115)5.29786667
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.29675255
5regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.20111066
6locomotory exploration behavior (GO:0035641)5.17404849
7cardiac muscle hypertrophy (GO:0003300)5.16961708
8cardiac muscle contraction (GO:0060048)5.15077517
9synaptic vesicle maturation (GO:0016188)5.14821988
10synaptic vesicle exocytosis (GO:0016079)5.13948532
11sarcomere organization (GO:0045214)5.05888492
12cardiac myofibril assembly (GO:0055003)4.98633114
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.97447875
14striated muscle hypertrophy (GO:0014897)4.88010796
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.85919062
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.74297678
17cardiac muscle adaptation (GO:0014887)4.70124775
18cardiac muscle hypertrophy in response to stress (GO:0014898)4.70124775
19muscle hypertrophy in response to stress (GO:0003299)4.70124775
20regulation of synaptic vesicle exocytosis (GO:2000300)4.67326068
21regulation of cardiac muscle cell contraction (GO:0086004)4.63825814
22neuron cell-cell adhesion (GO:0007158)4.62890087
23regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.59237001
24regulation of cell communication by electrical coupling (GO:0010649)4.58341647
25protein localization to synapse (GO:0035418)4.53742518
26regulation of glutamate receptor signaling pathway (GO:1900449)4.48272892
27glutamate secretion (GO:0014047)4.44542841
28regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.37652143
29regulation of synapse structural plasticity (GO:0051823)4.32918998
30gamma-aminobutyric acid transport (GO:0015812)4.32336161
31ionotropic glutamate receptor signaling pathway (GO:0035235)4.32082916
32neurotransmitter-gated ion channel clustering (GO:0072578)4.28700091
33muscle hypertrophy (GO:0014896)4.25609890
34cellular potassium ion homeostasis (GO:0030007)4.24921882
35detection of calcium ion (GO:0005513)4.21137775
36myofibril assembly (GO:0030239)4.19092989
37layer formation in cerebral cortex (GO:0021819)4.18056501
38positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.17809729
39regulation of synaptic vesicle transport (GO:1902803)4.17076963
40neurotransmitter secretion (GO:0007269)4.16213613
41exploration behavior (GO:0035640)4.14056357
42neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)4.00108890
43cell communication by electrical coupling (GO:0010644)3.96214081
44synaptic transmission, glutamatergic (GO:0035249)3.95255539
45positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.93872947
46synaptic vesicle docking involved in exocytosis (GO:0016081)3.93508339
47sodium ion export (GO:0071436)3.92631795
48glutamate receptor signaling pathway (GO:0007215)3.90995762
49regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.90046904
50dendritic spine morphogenesis (GO:0060997)3.87391563
51cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.87269271
52membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.85813170
53neuronal action potential propagation (GO:0019227)3.85643436
54regulation of cardioblast differentiation (GO:0051890)3.79079942
55negative regulation of synaptic transmission, GABAergic (GO:0032229)3.78286935
56proline transport (GO:0015824)3.77409400
57muscle filament sliding (GO:0030049)3.75384289
58actin-myosin filament sliding (GO:0033275)3.75384289
59adult heart development (GO:0007512)3.73511339
60response to pheromone (GO:0019236)3.72915062
61ventricular cardiac muscle cell action potential (GO:0086005)3.72414873
62regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.71072500
63postsynaptic membrane organization (GO:0001941)3.70369491
64regulation of neuronal synaptic plasticity (GO:0048168)3.68197640
65ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.67829916
66regulation of the force of heart contraction (GO:0002026)3.66276399
67regulation of striated muscle contraction (GO:0006942)3.62552878
68neuron-neuron synaptic transmission (GO:0007270)3.62271442
69regulation of long-term neuronal synaptic plasticity (GO:0048169)3.60725264
70regulation of cardiac muscle contraction (GO:0055117)3.59920303
71synaptic vesicle endocytosis (GO:0048488)3.55831126
72cellular response to epinephrine stimulus (GO:0071872)3.54870939
73cerebellar granule cell differentiation (GO:0021707)3.54615281
74positive regulation of synapse maturation (GO:0090129)3.54335118
75regulation of relaxation of muscle (GO:1901077)3.54095599
76regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.53678287
77neurotransmitter transport (GO:0006836)3.51804443
78striated muscle contraction (GO:0006941)3.51775578
79cardiac muscle cell development (GO:0055013)3.49799431
80long-term memory (GO:0007616)3.49081423
81positive regulation of action potential (GO:0045760)3.48389127
82cardiac muscle tissue morphogenesis (GO:0055008)3.47577610
83transmission of nerve impulse (GO:0019226)3.45774709
84regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.45262106
85dendrite morphogenesis (GO:0048813)3.43231553
86neuron recognition (GO:0008038)3.43050189
87positive regulation of potassium ion transmembrane transport (GO:1901381)3.41847188
88response to auditory stimulus (GO:0010996)3.40285406
89G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.38367275
90regulation of heart rate (GO:0002027)3.38242876
91cell migration in hindbrain (GO:0021535)3.34812635
92auditory behavior (GO:0031223)3.34784105
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.30608847
94cerebellar Purkinje cell differentiation (GO:0021702)3.25732798
95cardiac cell development (GO:0055006)3.25084932
96gamma-aminobutyric acid signaling pathway (GO:0007214)3.24665841
97actomyosin structure organization (GO:0031032)3.24263725
98response to epinephrine (GO:0071871)3.24097949
99cardiac ventricle formation (GO:0003211)3.23878803
100regulation of excitatory postsynaptic membrane potential (GO:0060079)3.22200221
101potassium ion import (GO:0010107)3.21585777
102heart process (GO:0003015)3.18558863
103heart contraction (GO:0060047)3.18558863
104neuromuscular process controlling balance (GO:0050885)3.18135330
105regulation of neurotransmitter levels (GO:0001505)3.16775108
106cardiac chamber formation (GO:0003207)3.16769911
107positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.16619767
108regulation of neurotransmitter secretion (GO:0046928)3.16261515
109regulation of synaptic transmission, glutamatergic (GO:0051966)3.15179809
110positive regulation of membrane potential (GO:0045838)3.14913423
111negative regulation of potassium ion transmembrane transport (GO:1901380)3.14171538
112regulation of heart contraction (GO:0008016)3.12965940
113axonal fasciculation (GO:0007413)3.12809234
114central nervous system projection neuron axonogenesis (GO:0021952)3.12575768
115potassium ion homeostasis (GO:0055075)3.12503498
116response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.11964419
117negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.11433984
118regulation of postsynaptic membrane potential (GO:0060078)3.10776857
119regulation of vesicle fusion (GO:0031338)3.10737579
120muscle tissue morphogenesis (GO:0060415)3.10555251
121presynaptic membrane assembly (GO:0097105)3.08605457
122regulation of voltage-gated calcium channel activity (GO:1901385)3.08262479
123actin-mediated cell contraction (GO:0070252)3.08033355
124glycine transport (GO:0015816)3.07843272
125innervation (GO:0060384)3.06138303
126cardiac conduction (GO:0061337)3.05854068
127positive regulation of synapse assembly (GO:0051965)3.05809834
128L-amino acid import (GO:0043092)3.05661431
129membrane hyperpolarization (GO:0060081)3.05547387
130synapse assembly (GO:0007416)3.05134032
131membrane depolarization during action potential (GO:0086010)3.04604954
132cardiac muscle cell action potential (GO:0086001)3.04473941
133cardiac muscle cell action potential involved in contraction (GO:0086002)3.02729804
134positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02461655
135pyrimidine nucleobase catabolic process (GO:0006208)3.01928491
136regulation of synapse maturation (GO:0090128)3.00087356
137membrane repolarization (GO:0086009)2.98420825
138acidic amino acid transport (GO:0015800)2.98000030
139presynaptic membrane organization (GO:0097090)2.96547401
140long-term synaptic potentiation (GO:0060291)2.94035742
141regulation of neurotransmitter transport (GO:0051588)2.93934777
142cellular response to catecholamine stimulus (GO:0071870)2.92809148
143cellular response to monoamine stimulus (GO:0071868)2.92809148
144positive regulation of heart rate (GO:0010460)2.92746496
145regulation of synaptic plasticity (GO:0048167)2.92707615
146regulation of respiratory system process (GO:0044065)2.90191751
147activation of protein kinase A activity (GO:0034199)2.89587767
148regulation of dendritic spine morphogenesis (GO:0061001)2.88770521
149membrane depolarization (GO:0051899)2.87589595
150cell communication involved in cardiac conduction (GO:0086065)2.87472783
151adult walking behavior (GO:0007628)2.87103622
152cellular sodium ion homeostasis (GO:0006883)2.86600311
153neuromuscular process controlling posture (GO:0050884)2.85285848
154regulation of membrane repolarization (GO:0060306)2.84640509
155synapse organization (GO:0050808)2.84161231
156striated muscle adaptation (GO:0014888)2.83600779
157positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.83124681
158positive regulation of dendritic spine development (GO:0060999)2.82243152
159neuronal ion channel clustering (GO:0045161)2.82100061
160positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.82032459
161positive regulation of sodium ion transport (GO:0010765)2.75903547
162regulation of calcium ion transmembrane transporter activity (GO:1901019)2.75888134
163regulation of calcium ion transmembrane transport (GO:1903169)2.75888134
164regulation of sarcomere organization (GO:0060297)2.74060586
165sarcoplasmic reticulum calcium ion transport (GO:0070296)2.71430316
166relaxation of cardiac muscle (GO:0055119)2.71408222
167response to catecholamine (GO:0071869)2.69807451
168response to monoamine (GO:0071867)2.69807451
169response to inactivity (GO:0014854)2.68310727

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.90970807
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.18764442
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.16006386
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.13979441
5GBX2_23144817_ChIP-Seq_PC3_Human3.12427356
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.83459017
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.83459017
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.79043686
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.77532374
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.68808341
11REST_21632747_ChIP-Seq_MESCs_Mouse2.61072050
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.59290503
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.59006728
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.54666520
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.52011816
16DROSHA_22980978_ChIP-Seq_HELA_Human2.48245190
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.47981934
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.45088358
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.35357796
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.33534507
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.24878829
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.12336423
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.11085066
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.10545205
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.04493757
26TRIM28_21343339_ChIP-Seq_HEK293_Human2.02252310
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.99005369
28AR_21572438_ChIP-Seq_LNCaP_Human1.95876195
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90557988
30EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.77211886
31EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.64118007
32PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.63975189
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.63262316
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62532479
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59927171
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.56265317
37CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.54160172
38SMAD4_21799915_ChIP-Seq_A2780_Human1.53040792
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51067797
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50642085
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49933614
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46248682
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.45639083
44PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.45415945
45TBX20_22328084_ChIP-Seq_HEART_Mouse1.43079143
46TBX20_22080862_ChIP-Seq_HEART_Mouse1.43079143
47RING1B_27294783_Chip-Seq_ESCs_Mouse1.40267050
48CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40125182
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39397142
50TAF15_26573619_Chip-Seq_HEK293_Human1.35582505
51ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33546465
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30534269
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29243615
54ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28195473
55* SOX2_21211035_ChIP-Seq_LN229_Gbm1.26627173
56SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.26196766
57P300_19829295_ChIP-Seq_ESCs_Human1.24362066
58ZNF274_21170338_ChIP-Seq_K562_Hela1.23297103
59TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21892685
60IGF1R_20145208_ChIP-Seq_DFB_Human1.21635009
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21042305
62AR_25329375_ChIP-Seq_VCAP_Human1.19869096
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.19577159
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18750359
65AR_19668381_ChIP-Seq_PC3_Human1.17748674
66RNF2_27304074_Chip-Seq_NSC_Mouse1.17372889
67RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.16770232
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15246244
69FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.14569094
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.14200344
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.12643213
72DNAJC2_21179169_ChIP-ChIP_NT2_Human1.12075032
73PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.11940176
74PIAS1_25552417_ChIP-Seq_VCAP_Human1.11347396
75OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09733281
76TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08899043
77WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08210698
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04921488
79PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.04497347
80NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04185488
81STAT3_23295773_ChIP-Seq_U87_Human1.03361585
82MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.02610847
83CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01821798
84P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01414464
85YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01057099
86MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00470886
87KDM2B_26808549_Chip-Seq_K562_Human0.99397158
88* RARG_19884340_ChIP-ChIP_MEFs_Mouse0.98766004
89TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.97670739
90ARNT_22903824_ChIP-Seq_MCF-7_Human0.96741949
91ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96391919
92TP53_20018659_ChIP-ChIP_R1E_Mouse0.95317085
93ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94927583
94TCF4_23295773_ChIP-Seq_U87_Human0.94736456
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94724093
96TET1_21490601_ChIP-Seq_MESCs_Mouse0.94299391
97RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94255840
98VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94186076
99ISL1_27105846_Chip-Seq_CPCs_Mouse0.93650492
100RUNX2_22187159_ChIP-Seq_PCA_Human0.93468682
101AHR_22903824_ChIP-Seq_MCF-7_Human0.92613268
102SMAD3_21741376_ChIP-Seq_ESCs_Human0.92059426
103ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91508820
104SMAD4_21741376_ChIP-Seq_HESCs_Human0.91356443
105* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90709640
106* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.90088008
107* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88591212
108EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.87809159
109TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87794789
110POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87794789
111PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.85498736
112AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85473385
113POU3F2_20337985_ChIP-ChIP_501MEL_Human0.84902048
114* TP53_23651856_ChIP-Seq_MEFs_Mouse0.84513030
115PRDM14_20953172_ChIP-Seq_ESCs_Human0.84357258
116UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83985324
117NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.83655742
118EP300_21415370_ChIP-Seq_HL-1_Mouse0.82470536
119ER_23166858_ChIP-Seq_MCF-7_Human0.82204963
120SMAD3_21741376_ChIP-Seq_HESCs_Human0.81034365
121CTCF_27219007_Chip-Seq_Bcells_Human0.80796153
122ESR2_21235772_ChIP-Seq_MCF-7_Human0.79633518
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.79209565
124TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.78548291
125FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.78065217
126CLOCK_20551151_ChIP-Seq_293T_Human0.77706423
127LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75094982

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.41000685
2MP0003880_abnormal_central_pattern3.92033546
3MP0003635_abnormal_synaptic_transmissio3.77982072
4MP0009046_muscle_twitch3.41254917
5MP0005423_abnormal_somatic_nervous3.40214047
6MP0004270_analgesia3.08233697
7MP0009745_abnormal_behavioral_response3.02853285
8MP0002063_abnormal_learning/memory/cond2.94852976
9MP0002064_seizures2.89487144
10MP0001968_abnormal_touch/_nociception2.69538235
11MP0001486_abnormal_startle_reflex2.65156922
12MP0002572_abnormal_emotion/affect_behav2.58742958
13MP0002734_abnormal_mechanical_nocicepti2.46904810
14MP0002272_abnormal_nervous_system2.45326920
15MP0005645_abnormal_hypothalamus_physiol2.45192113
16MP0005330_cardiomyopathy2.38316464
17MP0002735_abnormal_chemical_nociception2.26072847
18MP0000749_muscle_degeneration2.23485473
19MP0001440_abnormal_grooming_behavior2.22213290
20MP0002736_abnormal_nociception_after2.15792034
21MP0008569_lethality_at_weaning2.07524367
22MP0000778_abnormal_nervous_system2.05138757
23MP0002733_abnormal_thermal_nociception2.04252867
24MP0002067_abnormal_sensory_capabilities2.01937615
25MP0006138_congestive_heart_failure1.99788186
26MP0002184_abnormal_innervation1.98248541
27MP0004858_abnormal_nervous_system1.94583682
28MP0001970_abnormal_pain_threshold1.89742107
29MP0001544_abnormal_cardiovascular_syste1.88106738
30MP0005385_cardiovascular_system_phenoty1.88106738
31MP0006276_abnormal_autonomic_nervous1.86139816
32MP0001501_abnormal_sleep_pattern1.84684787
33MP0004087_abnormal_muscle_fiber1.83687724
34MP0002557_abnormal_social/conspecific_i1.82512744
35MP0003329_amyloid_beta_deposits1.82331905
36MP0005386_behavior/neurological_phenoty1.77571549
37MP0004924_abnormal_behavior1.77571549
38MP0001984_abnormal_olfaction1.74024785
39MP0000751_myopathy1.73117150
40MP0008775_abnormal_heart_ventricle1.72999270
41MP0002822_catalepsy1.72974121
42MP0009780_abnormal_chondrocyte_physiolo1.71648665
43MP0005670_abnormal_white_adipose1.71484250
44MP0005646_abnormal_pituitary_gland1.68042490
45MP0004885_abnormal_endolymph1.62128654
46MP0004811_abnormal_neuron_physiology1.61146728
47MP0010630_abnormal_cardiac_muscle1.60181307
48MP0000955_abnormal_spinal_cord1.55189952
49MP0002127_abnormal_cardiovascular_syste1.52982003
50MP0002837_dystrophic_cardiac_calcinosis1.51583966
51MP0002882_abnormal_neuron_morphology1.48423788
52MP0001502_abnormal_circadian_rhythm1.48365588
53MP0002909_abnormal_adrenal_gland1.46790489
54MP0002269_muscular_atrophy1.45940767
55MP0003879_abnormal_hair_cell1.44256444
56MP0004215_abnormal_myocardial_fiber1.43875293
57MP0004130_abnormal_muscle_cell1.43758371
58MP0004142_abnormal_muscle_tone1.42415242
59MP0000569_abnormal_digit_pigmentation1.40677110
60MP0002066_abnormal_motor_capabilities/c1.40249173
61MP0002106_abnormal_muscle_physiology1.38087556
62MP0001529_abnormal_vocalization1.37993692
63MP0003646_muscle_fatigue1.34939197
64MP0010368_abnormal_lymphatic_system1.32506924
65MP0003279_aneurysm1.29422671
66MP0003137_abnormal_impulse_conducting1.26910587
67MP0000750_abnormal_muscle_regeneration1.26298464
68MP0005551_abnormal_eye_electrophysiolog1.25646152
69MP0003787_abnormal_imprinting1.23349258
70MP0001188_hyperpigmentation1.21766726
71MP0002638_abnormal_pupillary_reflex1.19744376
72MP0002152_abnormal_brain_morphology1.18690821
73MP0003633_abnormal_nervous_system1.18528392
74MP0002332_abnormal_exercise_endurance1.18428911
75MP0005369_muscle_phenotype1.15086971
76MP0001905_abnormal_dopamine_level1.14360289
77MP0004145_abnormal_muscle_electrophysio1.11808348
78MP0000759_abnormal_skeletal_muscle1.11417176
79MP0003634_abnormal_glial_cell1.11067889
80MP0009384_cardiac_valve_regurgitation1.08619735
81MP0003828_pulmonary_edema1.08568843
82MP0003690_abnormal_glial_cell1.07721415
83MP0003631_nervous_system_phenotype1.07252317
84MP0000747_muscle_weakness1.06680762
85MP0005165_increased_susceptibility_to1.06290976
86MP0004085_abnormal_heartbeat1.05243017
87MP0002295_abnormal_pulmonary_circulatio1.04888003
88MP0004742_abnormal_vestibular_system1.03668975
89MP0005503_abnormal_tendon_morphology1.03234729
90MP0008004_abnormal_stomach_pH1.03055835
91MP0000631_abnormal_neuroendocrine_gland1.01134612
92MP0003122_maternal_imprinting0.98291437
93MP0002229_neurodegeneration0.96747310
94MP0002752_abnormal_somatic_nervous0.94354363
95MP0008995_early_reproductive_senescence0.94052425
96MP0002090_abnormal_vision0.93439285
97MP0001958_emphysema0.91426257
98MP0003632_abnormal_nervous_system0.90924438
99MP0004233_abnormal_muscle_weight0.89441673
100MP0001963_abnormal_hearing_physiology0.86752839
101MP0000920_abnormal_myelination0.82928745
102MP0002069_abnormal_eating/drinking_beha0.82593020
103MP0004484_altered_response_of0.82045390
104MP0005394_taste/olfaction_phenotype0.81444706
105MP0005499_abnormal_olfactory_system0.81444706
106MP0000639_abnormal_adrenal_gland0.80630958
107MP0002234_abnormal_pharynx_morphology0.78495347
108MP0008438_abnormal_cutaneous_collagen0.78160753
109MP0006072_abnormal_retinal_apoptosis0.76532428
110MP0000026_abnormal_inner_ear0.76062027
111MP0008872_abnormal_physiological_respon0.74894430
112MP0003283_abnormal_digestive_organ0.73824449
113MP0003221_abnormal_cardiomyocyte_apopto0.72580791
114MP0001299_abnormal_eye_distance/0.71557492
115MP0001485_abnormal_pinna_reflex0.71072568
116MP0001177_atelectasis0.71044704
117MP0000013_abnormal_adipose_tissue0.70035516
118MP0005623_abnormal_meninges_morphology0.69160964
119MP0000230_abnormal_systemic_arterial0.67870962
120MP0000604_amyloidosis0.67782542
121MP0005595_abnormal_vascular_smooth0.67277483
122MP0005409_darkened_coat_color0.66325598
123MP0005253_abnormal_eye_physiology0.65462833
124MP0010386_abnormal_urinary_bladder0.64886478
125MP0002972_abnormal_cardiac_muscle0.64146891
126MP0005620_abnormal_muscle_contractility0.63956098
127MP0003861_abnormal_nervous_system0.63834077
128MP0003075_altered_response_to0.63607326
129MP0005187_abnormal_penis_morphology0.61903129
130MP0006292_abnormal_olfactory_placode0.60037594
131MP0000767_abnormal_smooth_muscle0.60026631
132MP0004036_abnormal_muscle_relaxation0.59820660
133MP0005535_abnormal_body_temperature0.58657727
134MP0008874_decreased_physiological_sensi0.57872097
135MP0004084_abnormal_cardiac_muscle0.56612423
136MP0004510_myositis0.55872731

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.20353463
2Myokymia (HP:0002411)5.89935148
3Progressive cerebellar ataxia (HP:0002073)4.91991428
4Epileptic encephalopathy (HP:0200134)4.84630364
5Focal seizures (HP:0007359)4.73903561
6Visual hallucinations (HP:0002367)4.71197490
7Hyporeflexia of lower limbs (HP:0002600)4.52134743
8Heart block (HP:0012722)4.43267897
9Action tremor (HP:0002345)4.28231725
10Febrile seizures (HP:0002373)4.23149710
11Abnormal atrioventricular conduction (HP:0005150)4.20022825
12Lipoatrophy (HP:0100578)4.10546088
13Atrioventricular block (HP:0001678)4.10215530
14Ventricular tachycardia (HP:0004756)4.04682363
15Abnormality of the calf musculature (HP:0001430)4.00396452
16Muscle fiber splitting (HP:0003555)3.93037219
17Ventricular arrhythmia (HP:0004308)3.74153391
18Asymmetric septal hypertrophy (HP:0001670)3.71361491
19Atonic seizures (HP:0010819)3.62152781
20Hypoplastic left heart (HP:0004383)3.57829932
21Anomalous pulmonary venous return (HP:0010772)3.55041508
22Supranuclear gaze palsy (HP:0000605)3.49087437
23Broad-based gait (HP:0002136)3.44445086
24Right ventricular cardiomyopathy (HP:0011663)3.42557232
25Dilated cardiomyopathy (HP:0001644)3.40547972
26Absence seizures (HP:0002121)3.35629205
27Dysdiadochokinesis (HP:0002075)3.35227465
28Generalized tonic-clonic seizures (HP:0002069)3.33868327
29Ankle clonus (HP:0011448)3.28674374
30Abnormality of the pulmonary veins (HP:0011718)3.26669924
31Megalencephaly (HP:0001355)3.21302338
32Mutism (HP:0002300)3.19134103
33EMG: neuropathic changes (HP:0003445)3.17327282
34EMG: myopathic abnormalities (HP:0003458)3.11382604
35Hemiparesis (HP:0001269)3.09716429
36Distal lower limb muscle weakness (HP:0009053)3.08360013
37Subaortic stenosis (HP:0001682)3.04342765
38Abnormality of the left ventricular outflow tract (HP:0011103)3.04342765
39Dialeptic seizures (HP:0011146)3.03354155
40Hypoplastic heart (HP:0001961)3.02008107
41Calf muscle hypertrophy (HP:0008981)3.01466739
42Abnormal eating behavior (HP:0100738)3.00508823
43Depression (HP:0000716)2.99631801
44Left ventricular hypertrophy (HP:0001712)2.99179919
45Gaze-evoked nystagmus (HP:0000640)2.94254020
46Anxiety (HP:0000739)2.89986279
47Poor eye contact (HP:0000817)2.89301767
48Neurofibrillary tangles (HP:0002185)2.82865794
49Diplopia (HP:0000651)2.81895978
50Abnormality of binocular vision (HP:0011514)2.81895978
51Limb dystonia (HP:0002451)2.81101012
52Hemiplegia (HP:0002301)2.80327115
53Dysmetria (HP:0001310)2.79745605
54Truncal ataxia (HP:0002078)2.78388152
55Genetic anticipation (HP:0003743)2.75795449
56Abnormality of the foot musculature (HP:0001436)2.74782475
57Palpitations (HP:0001962)2.71337421
58Ventricular fibrillation (HP:0001663)2.70560167
59Pheochromocytoma (HP:0002666)2.68157555
60Hyperventilation (HP:0002883)2.66119169
61Polyphagia (HP:0002591)2.65825344
62Postural instability (HP:0002172)2.64378891
63Type 1 muscle fiber predominance (HP:0003803)2.61535790
64Impaired social interactions (HP:0000735)2.59895955
65Abnormal social behavior (HP:0012433)2.59895955
66Urinary bladder sphincter dysfunction (HP:0002839)2.58181864
67Muscle hypertrophy of the lower extremities (HP:0008968)2.56749617
68Aplasia involving bones of the extremities (HP:0009825)2.52969140
69Aplasia involving bones of the upper limbs (HP:0009823)2.52969140
70Aplasia of the phalanges of the hand (HP:0009802)2.52969140
71Drooling (HP:0002307)2.46195841
72Excessive salivation (HP:0003781)2.46195841
73Intention tremor (HP:0002080)2.43158349
74Neck muscle weakness (HP:0000467)2.40114285
75Foot dorsiflexor weakness (HP:0009027)2.40071222
76Neuroendocrine neoplasm (HP:0100634)2.37524777
77Cerebral inclusion bodies (HP:0100314)2.37016336
78Increased variability in muscle fiber diameter (HP:0003557)2.36528099
79Urinary urgency (HP:0000012)2.35021981
80Prolonged QT interval (HP:0001657)2.33785821
81Mildly elevated creatine phosphokinase (HP:0008180)2.33379737
82Scanning speech (HP:0002168)2.29838183
83Torticollis (HP:0000473)2.29084193
84Difficulty climbing stairs (HP:0003551)2.26795324
85Fetal akinesia sequence (HP:0001989)2.26775351
86Impaired vibration sensation in the lower limbs (HP:0002166)2.26133147
87Rimmed vacuoles (HP:0003805)2.23653199
88Transposition of the great arteries (HP:0001669)2.22195515
89Abnormal connection of the cardiac segments (HP:0011545)2.22195515
90Abnormal ventriculo-arterial connection (HP:0011563)2.22195515
91Double outlet right ventricle (HP:0001719)2.21961025
92Congenital malformation of the right heart (HP:0011723)2.21961025
93Abnormal EKG (HP:0003115)2.21599666
94Epileptiform EEG discharges (HP:0011182)2.21475586
95Spastic gait (HP:0002064)2.19224477
96Agitation (HP:0000713)2.17425742
97EEG with generalized epileptiform discharges (HP:0011198)2.16646992
98Status epilepticus (HP:0002133)2.14164449
99Abnormality of ocular smooth pursuit (HP:0000617)2.13707684
100Impaired smooth pursuit (HP:0007772)2.11873132
101Amblyopia (HP:0000646)2.11513809
102Ragged-red muscle fibers (HP:0003200)2.11460958
103Bradykinesia (HP:0002067)2.11319986
104Bradycardia (HP:0001662)2.11252572
105Hypsarrhythmia (HP:0002521)2.09913983
106Abnormality of the corticospinal tract (HP:0002492)2.09506797
107Exercise-induced myalgia (HP:0003738)2.08469220
108Gonadal dysgenesis (HP:0000133)2.07238897
109Lower limb muscle weakness (HP:0007340)2.05332138
110Progressive inability to walk (HP:0002505)2.04335123
111Obstructive sleep apnea (HP:0002870)2.04334814
112Bundle branch block (HP:0011710)2.04191349
113Narrow nasal bridge (HP:0000446)2.01343477
114Lower limb amyotrophy (HP:0007210)2.00618253
115Postural tremor (HP:0002174)2.00294984
116Testicular neoplasm (HP:0010788)2.00127800
117Stereotypic behavior (HP:0000733)1.99974576
118Primary atrial arrhythmia (HP:0001692)1.99895143
119Focal dystonia (HP:0004373)1.99823805
120Syncope (HP:0001279)1.99567338
121Atrial fibrillation (HP:0005110)1.99563893
122Protrusio acetabuli (HP:0003179)1.99024878
123Dysmetric saccades (HP:0000641)1.98361236
124Sudden death (HP:0001699)1.98106326
125Gait imbalance (HP:0002141)1.97882634
126Upper limb amyotrophy (HP:0009129)1.97488965
127Distal upper limb amyotrophy (HP:0007149)1.97488965
128Hand muscle atrophy (HP:0009130)1.96632507
129Myotonia (HP:0002486)1.96531128
130Aplasia/Hypoplasia of the brainstem (HP:0007362)1.94705021
131Hypoplasia of the brainstem (HP:0002365)1.94705021
132Increased connective tissue (HP:0009025)1.92544350
133Scapular winging (HP:0003691)1.90593010
134Steppage gait (HP:0003376)1.90180238
135Incomplete penetrance (HP:0003829)1.89019181
136Mesangial abnormality (HP:0001966)1.88954855
137Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.88258039
138Retinal dysplasia (HP:0007973)1.87565698
139Sleep apnea (HP:0010535)1.86172170
140Distal lower limb amyotrophy (HP:0008944)1.85387481
141Central scotoma (HP:0000603)1.84690862
142Insidious onset (HP:0003587)1.84549977
143Termporal pattern (HP:0011008)1.84549977
144Supraventricular tachycardia (HP:0004755)1.84013095
145Abnormality of the lower motor neuron (HP:0002366)1.83877662
146Limb-girdle muscle atrophy (HP:0003797)1.83769287
147Abnormality of skeletal muscle fiber size (HP:0012084)1.83711482
148Specific learning disability (HP:0001328)1.83429258
149Amyotrophic lateral sclerosis (HP:0007354)1.82762754
150Papilledema (HP:0001085)1.79710357
151Sudden cardiac death (HP:0001645)1.79446319
152Insomnia (HP:0100785)1.79368396
153Neoplasm of the peripheral nervous system (HP:0100007)1.78889912
154Limb-girdle muscle weakness (HP:0003325)1.78312910
155Diaphragmatic weakness (HP:0009113)1.78113872
156Hypoventilation (HP:0002791)1.76902646
157Craniofacial dystonia (HP:0012179)1.76837455
158Supraventricular arrhythmia (HP:0005115)1.76569111
159Complete atrioventricular canal defect (HP:0001674)1.76152448
160Abnormality of the vocal cords (HP:0008777)1.75328676
161Bulbar palsy (HP:0001283)1.74998399
162Horizontal nystagmus (HP:0000666)1.74780398
163Abnormality of the tricuspid valve (HP:0001702)1.72502566
164Abnormality of the shoulder girdle musculature (HP:0001435)1.69078429
165Periauricular skin pits (HP:0100277)1.69016001
166Preauricular pit (HP:0004467)1.69016001
167Centrally nucleated skeletal muscle fibers (HP:0003687)1.64745953
168Atrioventricular canal defect (HP:0006695)1.64261247
169Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.63030788
170Degeneration of the lateral corticospinal tracts (HP:0002314)1.63030788

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MYLK5.27758317
2MARK14.40467311
3TTN4.00344006
4NTRK33.51217900
5EPHA43.35332149
6MAP3K43.14072407
7NTRK22.84626693
8MAP3K92.69614855
9MINK12.69236409
10PHKG22.66058555
11PHKG12.66058555
12MAP2K72.65764430
13PAK62.21594755
14LMTK22.17250596
15CASK2.10399485
16DAPK22.09756860
17MAPK131.84127397
18TNIK1.82166828
19MAP2K41.66691420
20MAP3K121.64882831
21MAP3K61.60090313
22PRPF4B1.48118846
23CAMKK11.45526438
24PLK21.42922962
25OBSCN1.42816372
26MUSK1.42704274
27CDK51.42262500
28NTRK11.38298709
29GRK51.34586568
30EPHA31.34513872
31PRKD31.31698262
32SGK2231.29520349
33SGK4941.29520349
34PDK31.27914926
35PDK41.27914926
36PINK11.24512491
37STK381.22586294
38UHMK11.22158829
39PRKD11.18261762
40PRKCG1.17939439
41KSR11.17230773
42SIK21.15403966
43SGK21.13451694
44CDK191.05313975
45DYRK1A0.98039553
46CAMK2A0.97090756
47TESK10.96228715
48CAMKK20.95938879
49LATS20.95603248
50DAPK10.93015887
51GRK70.92328649
52EPHB20.90415458
53KSR20.89599873
54PNCK0.88889827
55CDK180.88784207
56SGK30.88113886
57MAP3K70.87333292
58PAK30.87193694
59CDK150.86396414
60CAMK10.85148774
61TYRO30.83629788
62PRKAA10.83194667
63TAOK10.80602423
64CDK140.79941503
65PRKCE0.79614848
66PKN10.79135705
67STK110.78990397
68DDR20.77764953
69AKT30.77437054
70PRKCH0.77350430
71EPHB10.76658855
72ERBB30.75819432
73MAP3K50.75478237
74CDK11A0.74439617
75WNK10.73574273
76SIK30.73253166
77PDGFRA0.73091151
78RPS6KC10.72763736
79RPS6KL10.72763736
80DYRK20.72338663
81FES0.71283742
82DAPK30.70418409
83CSNK1G20.70171121
84MARK20.70093337
85SGK10.69130557
86STK38L0.68548767
87PIK3CA0.67117060
88CDC42BPA0.66723552
89CAMK2B0.66087932
90CAMK1G0.62685599
91RPS6KA60.62619591
92PDK20.61634565
93DMPK0.60642868
94MAPK120.60590180
95MAPK40.59260598
96RIPK10.57247387
97RIPK40.56869785
98CAMK2D0.56610810
99RET0.55961038
100ROCK20.54422939
101STK40.54111145
102DYRK1B0.53065294
103CAMK2G0.52257177
104WNK30.51768265
105ROCK10.51376762
106NEK60.50534000
107PRKCZ0.50406502
108OXSR10.49217896
109MAP3K20.48896577
110RPS6KA30.48511385
111ALK0.48275680
112AKT20.47905147
113CAMK40.47444514
114NEK90.47071191
115MAP4K20.45240277
116BCKDK0.44987280
117LIMK10.43747275
118RPS6KA20.43286545
119MAPK70.42022295
120PRKACA0.42007515
121FYN0.41768646
122TIE10.41759671
123BCR0.40597047
124ICK0.40411528
125PDK10.39919069
126PRKG10.39269525
127ADRBK10.37881843
128BMPR1B0.35205255
129PDPK10.34872584
130ARAF0.33836715
131PRKACG0.33782460
132MAPK100.33719254
133IRAK20.33408952

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.07974924
2Synaptic vesicle cycle_Homo sapiens_hsa047213.25690142
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.00990134
4GABAergic synapse_Homo sapiens_hsa047272.88732532
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.70102738
6Glutamatergic synapse_Homo sapiens_hsa047242.63362838
7Circadian entrainment_Homo sapiens_hsa047132.60368449
8Morphine addiction_Homo sapiens_hsa050322.47182451
9Olfactory transduction_Homo sapiens_hsa047402.32887678
10Long-term potentiation_Homo sapiens_hsa047202.15069665
112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.12919606
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.06771496
13Salivary secretion_Homo sapiens_hsa049702.01958865
14Amphetamine addiction_Homo sapiens_hsa050311.99411897
15Dopaminergic synapse_Homo sapiens_hsa047281.98697764
16Taste transduction_Homo sapiens_hsa047421.90336725
17Insulin secretion_Homo sapiens_hsa049111.86716665
18Cholinergic synapse_Homo sapiens_hsa047251.80609121
19Gastric acid secretion_Homo sapiens_hsa049711.76374303
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73338229
21Long-term depression_Homo sapiens_hsa047301.67136698
22Serotonergic synapse_Homo sapiens_hsa047261.63083042
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.58517158
24Cardiac muscle contraction_Homo sapiens_hsa042601.55788169
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.54075484
26Cocaine addiction_Homo sapiens_hsa050301.52741390
27Calcium signaling pathway_Homo sapiens_hsa040201.47381833
28Oxytocin signaling pathway_Homo sapiens_hsa049211.45751867
29Renin secretion_Homo sapiens_hsa049241.44956638
30Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.44532485
31Axon guidance_Homo sapiens_hsa043601.35068860
32Nitrogen metabolism_Homo sapiens_hsa009101.29062670
33Collecting duct acid secretion_Homo sapiens_hsa049661.26619266
34Gap junction_Homo sapiens_hsa045401.25718126
35cAMP signaling pathway_Homo sapiens_hsa040241.25514096
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25279151
37GnRH signaling pathway_Homo sapiens_hsa049121.22393133
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.18943106
39Dilated cardiomyopathy_Homo sapiens_hsa054141.16944791
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13004812
41Type II diabetes mellitus_Homo sapiens_hsa049301.05775840
42Prion diseases_Homo sapiens_hsa050201.02345928
43Arginine and proline metabolism_Homo sapiens_hsa003301.02234561
44cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98776568
45Propanoate metabolism_Homo sapiens_hsa006400.98197412
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.96672936
47Phenylalanine metabolism_Homo sapiens_hsa003600.95437480
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92865238
49Melanogenesis_Homo sapiens_hsa049160.91842158
50Estrogen signaling pathway_Homo sapiens_hsa049150.90761173
51Fatty acid biosynthesis_Homo sapiens_hsa000610.90624803
52Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86832992
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86739706
54Arginine biosynthesis_Homo sapiens_hsa002200.86514880
55Phototransduction_Homo sapiens_hsa047440.86490326
56ErbB signaling pathway_Homo sapiens_hsa040120.85905374
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.80823872
58Glioma_Homo sapiens_hsa052140.80161486
59Pyruvate metabolism_Homo sapiens_hsa006200.78216702
60Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.78127400
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76201506
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.75752522
63Carbon metabolism_Homo sapiens_hsa012000.75016238
64PPAR signaling pathway_Homo sapiens_hsa033200.74685999
65Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74579823
66Dorso-ventral axis formation_Homo sapiens_hsa043200.73829192
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73174142
68Pancreatic secretion_Homo sapiens_hsa049720.72769076
69Alzheimers disease_Homo sapiens_hsa050100.72519839
70Vibrio cholerae infection_Homo sapiens_hsa051100.72337039
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71749395
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69002668
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68732137
74MAPK signaling pathway_Homo sapiens_hsa040100.67407433
75ECM-receptor interaction_Homo sapiens_hsa045120.66989607
76Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65280159
77Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64170760
78AMPK signaling pathway_Homo sapiens_hsa041520.62642681
79Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62587172
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.62471252
81Fatty acid elongation_Homo sapiens_hsa000620.61815888
82Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61730771
83Oxidative phosphorylation_Homo sapiens_hsa001900.61473824
84Focal adhesion_Homo sapiens_hsa045100.61091669
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58955427
86Fatty acid metabolism_Homo sapiens_hsa012120.58791856
87Thyroid hormone synthesis_Homo sapiens_hsa049180.56695263
88Oocyte meiosis_Homo sapiens_hsa041140.56534081
89Parkinsons disease_Homo sapiens_hsa050120.56493906
90Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56301929
91Ras signaling pathway_Homo sapiens_hsa040140.55976996
92Vitamin B6 metabolism_Homo sapiens_hsa007500.55441552
93Fatty acid degradation_Homo sapiens_hsa000710.55393692
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.53994393
95Choline metabolism in cancer_Homo sapiens_hsa052310.53273177
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52578661
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.51972516
98Butanoate metabolism_Homo sapiens_hsa006500.50544364
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50164869
100Rap1 signaling pathway_Homo sapiens_hsa040150.49256213
101Glucagon signaling pathway_Homo sapiens_hsa049220.47424643
102Tight junction_Homo sapiens_hsa045300.47146277
103Circadian rhythm_Homo sapiens_hsa047100.47093411
104Renal cell carcinoma_Homo sapiens_hsa052110.45753274
105Type I diabetes mellitus_Homo sapiens_hsa049400.45040832
106Alcoholism_Homo sapiens_hsa050340.44373822
107beta-Alanine metabolism_Homo sapiens_hsa004100.43679917
108Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42912632
109Wnt signaling pathway_Homo sapiens_hsa043100.42442965
110Endometrial cancer_Homo sapiens_hsa052130.41856639
111Ovarian steroidogenesis_Homo sapiens_hsa049130.40636195
112Biosynthesis of amino acids_Homo sapiens_hsa012300.39971157
113Endocytosis_Homo sapiens_hsa041440.39739476
114Hedgehog signaling pathway_Homo sapiens_hsa043400.36374436
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36042698
116Insulin signaling pathway_Homo sapiens_hsa049100.34834316
117Huntingtons disease_Homo sapiens_hsa050160.34106012
118Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.33317769
119Bile secretion_Homo sapiens_hsa049760.32355109
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.32238199
121VEGF signaling pathway_Homo sapiens_hsa043700.32206854
122Inositol phosphate metabolism_Homo sapiens_hsa005620.29625792
123Colorectal cancer_Homo sapiens_hsa052100.28963387
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.28835357
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.27887894

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