CSAG2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of oxidative stress-induced neuron death (GO:1903203)7.43217385
2regulation of DNA endoreduplication (GO:0032875)6.81000046
3cullin deneddylation (GO:0010388)6.32541697
4protein deneddylation (GO:0000338)5.93021505
5positive regulation of cellular response to oxidative stress (GO:1900409)5.77564420
6positive regulation of response to oxidative stress (GO:1902884)5.77564420
7DNA strand elongation involved in DNA replication (GO:0006271)5.17306274
8DNA strand elongation (GO:0022616)4.90170971
9positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc4.88731004
10mitochondrial RNA metabolic process (GO:0000959)4.88368467
11negative regulation of protein acetylation (GO:1901984)4.79159035
12DNA replication checkpoint (GO:0000076)4.74608957
13regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.52869611
14DNA replication initiation (GO:0006270)4.44254026
15maturation of 5.8S rRNA (GO:0000460)4.42271452
16positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)4.38814810
17ether lipid metabolic process (GO:0046485)4.30064253
18negative regulation of DNA-dependent DNA replication (GO:2000104)4.20939983
19gonadal mesoderm development (GO:0007506)4.14511393
20mRNA cleavage (GO:0006379)4.14131092
21negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.82114917
22mitochondrial respiratory chain complex assembly (GO:0033108)3.81295638
23DNA deamination (GO:0045006)3.77020758
24pseudouridine synthesis (GO:0001522)3.72931428
25nucleobase biosynthetic process (GO:0046112)3.71426701
26mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.58041457
27negative regulation of JAK-STAT cascade (GO:0046426)3.48093012
28establishment of epithelial cell polarity (GO:0090162)3.47974320
29glycerol ether metabolic process (GO:0006662)3.43851408
30regulation of retinoic acid receptor signaling pathway (GO:0048385)3.41053073
31telomere maintenance via semi-conservative replication (GO:0032201)3.41052968
32proteasome assembly (GO:0043248)3.40421567
33negative regulation of smooth muscle cell differentiation (GO:0051151)3.39493522
34rRNA modification (GO:0000154)3.38292121
35ribosome assembly (GO:0042255)3.36408616
36protein K6-linked ubiquitination (GO:0085020)3.34891075
37magnesium ion transport (GO:0015693)3.31553014
38postreplication repair (GO:0006301)3.30589432
39Arp2/3 complex-mediated actin nucleation (GO:0034314)3.29736713
40regulation of double-strand break repair via homologous recombination (GO:0010569)3.27612347
41protein import into peroxisome matrix (GO:0016558)3.20714546
42monoubiquitinated protein deubiquitination (GO:0035520)3.18739332
43protein polyglutamylation (GO:0018095)3.16370527
44neurotransmitter catabolic process (GO:0042135)3.15884029
45ether metabolic process (GO:0018904)3.14821452
46positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.05682784
47negative regulation of histone acetylation (GO:0035067)3.05385793
48ovulation cycle (GO:0042698)3.05303569
49negative regulation of granulocyte differentiation (GO:0030853)3.03048818
50DNA unwinding involved in DNA replication (GO:0006268)2.99347438
51regulation of histone phosphorylation (GO:0033127)2.97737378
52mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.96787337
53regulation of DNA-dependent DNA replication (GO:0090329)2.96039160
54tRNA aminoacylation for protein translation (GO:0006418)2.95566079
55purine nucleobase biosynthetic process (GO:0009113)2.94335193
56rRNA methylation (GO:0031167)2.92838250
57positive regulation of ligase activity (GO:0051351)2.92591790
58detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.89467799
59regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:22.87374110
60formation of translation preinitiation complex (GO:0001731)2.87340213
61actin nucleation (GO:0045010)2.86962529
62negative regulation of macrophage differentiation (GO:0045650)2.86178594
63nucleoside transmembrane transport (GO:1901642)2.85384929
64mitotic nuclear envelope disassembly (GO:0007077)2.84729848
65NADH dehydrogenase complex assembly (GO:0010257)2.82132691
66mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.82132691
67mitochondrial respiratory chain complex I assembly (GO:0032981)2.82132691
68ribonucleoprotein complex disassembly (GO:0032988)2.81241072
69telomere maintenance via recombination (GO:0000722)2.81136741
70mitotic recombination (GO:0006312)2.77469573
71phenylpropanoid metabolic process (GO:0009698)2.76774166
72regulation of triglyceride biosynthetic process (GO:0010866)2.76366869
73energy coupled proton transport, down electrochemical gradient (GO:0015985)2.75691057
74ATP synthesis coupled proton transport (GO:0015986)2.75691057
75tRNA aminoacylation (GO:0043039)2.75370715
76amino acid activation (GO:0043038)2.75370715
77protein complex biogenesis (GO:0070271)2.73117516
78establishment of integrated proviral latency (GO:0075713)2.72052029
79response to growth hormone (GO:0060416)2.71597651
80flavonoid metabolic process (GO:0009812)2.70366150
81nucleotide-excision repair, DNA gap filling (GO:0006297)2.70104256
82glycerophospholipid catabolic process (GO:0046475)2.66749126
83histone H2A ubiquitination (GO:0033522)2.64757282
84ncRNA 3-end processing (GO:0043628)2.63873770
85nuclear pore complex assembly (GO:0051292)2.63617017
86nucleobase-containing small molecule interconversion (GO:0015949)2.62934249
87regulation of ubiquitin-protein transferase activity (GO:0051438)2.61519701
88protein localization to peroxisome (GO:0072662)2.59291421
89protein targeting to peroxisome (GO:0006625)2.59291421
90establishment of protein localization to peroxisome (GO:0072663)2.59291421
91positive regulation of histone H3-K4 methylation (GO:0051571)2.58768576
92DNA integrity checkpoint (GO:0031570)2.58471719
93regulation of nuclear cell cycle DNA replication (GO:0033262)2.56893047
94organelle disassembly (GO:1903008)2.56437078
95regulation of translational termination (GO:0006449)2.55937808
96phosphatidylethanolamine metabolic process (GO:0046337)2.54000295
97kinetochore organization (GO:0051383)2.53867733
98peroxisomal transport (GO:0043574)2.53413958
99ribosome biogenesis (GO:0042254)2.53144023
100DNA replication (GO:0006260)2.52789207

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.49266292
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.98599733
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.20027741
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.46210374
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.43508936
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.28901400
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.07834964
8ESR1_15608294_ChIP-ChIP_MCF-7_Human2.97248065
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.89972230
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.75669430
11PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.65216244
12SRF_21415370_ChIP-Seq_HL-1_Mouse2.61187848
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.59412531
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.59330650
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.52009701
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.48161047
17CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.46011344
18VDR_23849224_ChIP-Seq_CD4+_Human2.36773575
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.33142383
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.28611253
21ELK1_19687146_ChIP-ChIP_HELA_Human2.22525845
22AR_21909140_ChIP-Seq_LNCAP_Human2.10126798
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06460196
24FOXM1_23109430_ChIP-Seq_U2OS_Human2.06217778
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.03913172
26ZNF274_21170338_ChIP-Seq_K562_Hela2.00742717
27GABP_19822575_ChIP-Seq_HepG2_Human1.97868569
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.92999313
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91506398
30NELFA_20434984_ChIP-Seq_ESCs_Mouse1.89647519
31THAP11_20581084_ChIP-Seq_MESCs_Mouse1.85235366
32ZNF263_19887448_ChIP-Seq_K562_Human1.81721507
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.81009106
34FOXP3_21729870_ChIP-Seq_TREG_Human1.80021819
35E2F1_21310950_ChIP-Seq_MCF-7_Human1.79955503
36MYC_19079543_ChIP-ChIP_MESCs_Mouse1.79461783
37HOXB4_20404135_ChIP-ChIP_EML_Mouse1.79263933
38HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.74759583
39PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.66763635
40XRN2_22483619_ChIP-Seq_HELA_Human1.65917838
41TP63_19390658_ChIP-ChIP_HaCaT_Human1.61984875
42CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.60766428
43NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.58901947
44MYC_18940864_ChIP-ChIP_HL60_Human1.58504343
45CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.56857075
46FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.56411191
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.53723018
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50420689
49DCP1A_22483619_ChIP-Seq_HELA_Human1.48503578
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.43169069
51IRF1_19129219_ChIP-ChIP_H3396_Human1.42175647
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.39232423
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37385087
54BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.32953454
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31345127
56PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.30437615
57PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.27292967
58IRF8_22096565_ChIP-ChIP_GC-B_Human1.25835138
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.25185226
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23825895
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.22929317
62DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22721025
63TTF2_22483619_ChIP-Seq_HELA_Human1.22695515
64TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.22187232
65YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22161588
66KDM5A_27292631_Chip-Seq_BREAST_Human1.15021689
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13905072
68POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.12667541
69NCOR1_26117541_ChIP-Seq_K562_Human1.12014745
70SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.11672791
71TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.08394222
72MYCN_18555785_ChIP-Seq_MESCs_Mouse1.06264737
73KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.05807763
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02718943
75SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02089967
76ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.99471481
77ZFX_18555785_ChIP-Seq_MESCs_Mouse0.97793895
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92790569
79HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91462606
80TBX5_21415370_ChIP-Seq_HL-1_Mouse0.89900077
81ELF5_23300383_ChIP-Seq_T47D_Human0.88678879
82NANOG_21062744_ChIP-ChIP_HESCs_Human0.87735669
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83640616
84CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.81892783
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.81438794
86FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80957277
87IGF1R_20145208_ChIP-Seq_DFB_Human0.80425195
88ELF1_20517297_ChIP-Seq_JURKAT_Human0.80246561
89NANOG_18555785_ChIP-Seq_MESCs_Mouse0.79732229
90SOX17_20123909_ChIP-Seq_XEN_Mouse0.79312315
91VDR_22108803_ChIP-Seq_LS180_Human0.79051591
92ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.78078146
93TFEB_21752829_ChIP-Seq_HELA_Human0.77714005
94RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.77529021
95CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.76508611
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.75286268
97SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.75046078
98ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.74519970
99CIITA_25753668_ChIP-Seq_RAJI_Human0.73929891
100FOXP1_21924763_ChIP-Seq_HESCs_Human0.73593638

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008007_abnormal_cellular_replicative7.80449107
2MP0003806_abnormal_nucleotide_metabolis6.46315928
3MP0003315_abnormal_perineum_morphology3.87577619
4MP0005360_urolithiasis3.31321630
5MP0003786_premature_aging3.19553426
6MP0010094_abnormal_chromosome_stability3.14875319
7MP0002138_abnormal_hepatobiliary_system3.09926928
8MP0009697_abnormal_copulation3.02579192
9MP0003950_abnormal_plasma_membrane2.86005559
10MP0008058_abnormal_DNA_repair2.67888568
11MP0002876_abnormal_thyroid_physiology2.54867754
12MP0008995_early_reproductive_senescence2.53315180
13MP0003111_abnormal_nucleus_morphology2.43345577
14MP0005408_hypopigmentation2.38310104
15MP0001873_stomach_inflammation2.12422652
16MP0010234_abnormal_vibrissa_follicle1.90375662
17MP0000678_abnormal_parathyroid_gland1.85826377
18MP0005187_abnormal_penis_morphology1.81534656
19MP0003077_abnormal_cell_cycle1.81513111
20MP0005451_abnormal_body_composition1.80270869
21MP0000613_abnormal_salivary_gland1.75040191
22MP0006072_abnormal_retinal_apoptosis1.66228553
23MP0003186_abnormal_redox_activity1.64073255
24MP0004808_abnormal_hematopoietic_stem1.63755680
25MP0003693_abnormal_embryo_hatching1.63109056
26MP0010386_abnormal_urinary_bladder1.62753309
27MP0002938_white_spotting1.59188796
28MP0005058_abnormal_lysosome_morphology1.56637718
29MP0005171_absent_coat_pigmentation1.55990338
30MP0004043_abnormal_pH_regulation1.52417898
31MP0000681_abnormal_thyroid_gland1.50297585
32MP0008875_abnormal_xenobiotic_pharmacok1.48463553
33MP0002638_abnormal_pupillary_reflex1.46131915
34MP0004957_abnormal_blastocyst_morpholog1.45644860
35MP0010030_abnormal_orbit_morphology1.44261534
36MP0002332_abnormal_exercise_endurance1.39477877
37MP0006036_abnormal_mitochondrial_physio1.32139716
38MP0001919_abnormal_reproductive_system1.31172471
39MP0005389_reproductive_system_phenotype1.29752007
40MP0000372_irregular_coat_pigmentation1.27943589
41MP0006035_abnormal_mitochondrial_morpho1.21053908
42MP0003984_embryonic_growth_retardation1.20114664
43MP0003718_maternal_effect1.19855707
44MP0002088_abnormal_embryonic_growth/wei1.19565127
45MP0005266_abnormal_metabolism1.15237998
46MP0001697_abnormal_embryo_size1.14334090
47MP0001730_embryonic_growth_arrest1.11184108
48MP0000538_abnormal_urinary_bladder1.08160450
49MP0001764_abnormal_homeostasis1.06373107
50MP0002160_abnormal_reproductive_system1.04407035
51MP0000313_abnormal_cell_death1.04259720
52MP0005380_embryogenesis_phenotype1.04174502
53MP0001672_abnormal_embryogenesis/_devel1.04174502
54MP0002249_abnormal_larynx_morphology1.00251322
55MP0002132_abnormal_respiratory_system0.96418665
56MP0000647_abnormal_sebaceous_gland0.95754315
57MP0009250_abnormal_appendicular_skeleto0.92055163
58MP0005636_abnormal_mineral_homeostasis0.91920268
59MP0001881_abnormal_mammary_gland0.91568053
60MP0000358_abnormal_cell_content/0.90623548
61MP0001929_abnormal_gametogenesis0.89414532
62MP0000350_abnormal_cell_proliferation0.87323226
63MP0002210_abnormal_sex_determination0.82701317
64MP0005332_abnormal_amino_acid0.82204295
65MP0003868_abnormal_feces_composition0.80184384
66MP0002796_impaired_skin_barrier0.79059191
67MP0001661_extended_life_span0.76614927
68MP0001348_abnormal_lacrimal_gland0.76268751
69MP0005584_abnormal_enzyme/coenzyme_acti0.76026089
70MP0008057_abnormal_DNA_replication0.75908450
71MP0003937_abnormal_limbs/digits/tail_de0.75240284
72MP0002080_prenatal_lethality0.73880077
73MP0002019_abnormal_tumor_incidence0.72070923
74MP0000653_abnormal_sex_gland0.71916459
75MP0001270_distended_abdomen0.71282636
76MP0009765_abnormal_xenobiotic_induced0.71048841
77MP0004019_abnormal_vitamin_homeostasis0.71026188
78MP0008932_abnormal_embryonic_tissue0.70728671
79MP0005220_abnormal_exocrine_pancreas0.69425844
80MP0003698_abnormal_male_reproductive0.69325806
81MP0003252_abnormal_bile_duct0.66077592
82MP0001145_abnormal_male_reproductive0.64877208
83MP0005248_abnormal_Harderian_gland0.62848732
84MP0000703_abnormal_thymus_morphology0.61122399
85MP0000609_abnormal_liver_physiology0.59857751
86MP0002254_reproductive_system_inflammat0.59809421
87MP0004147_increased_porphyrin_level0.59308882
88MP0002085_abnormal_embryonic_tissue0.58624312
89MP0002086_abnormal_extraembryonic_tissu0.58430503
90MP0005410_abnormal_fertilization0.57940407
91MP0003943_abnormal_hepatobiliary_system0.56380839
92MP0005501_abnormal_skin_physiology0.53154665
93MP0003646_muscle_fatigue0.52784131
94MP0003699_abnormal_female_reproductive0.51662991
95MP0002909_abnormal_adrenal_gland0.51661699
96MP0008775_abnormal_heart_ventricle0.50947975
97MP0001243_abnormal_dermal_layer0.50234668
98MP0000685_abnormal_immune_system0.50006115
99MP0002161_abnormal_fertility/fecundity0.49250203
100MP0005319_abnormal_enzyme/_coenzyme0.48599117

Predicted human phenotypes

RankGene SetZ-score
1Delayed CNS myelination (HP:0002188)7.74518022
2Abnormality of the phalanges of the 2nd finger (HP:0009541)4.20717452
3Fibular aplasia (HP:0002990)4.05853408
4Hypoplasia of the uterus (HP:0000013)3.85024939
5Abnormality of the proximal phalanges of the hand (HP:0009834)3.73363153
6Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)3.71966458
7Dry hair (HP:0011359)3.58717074
8Birth length less than 3rd percentile (HP:0003561)3.44353703
9Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.42907639
10Autoimmune hemolytic anemia (HP:0001890)3.41539340
11Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)3.30474476
12Abnormality of the middle phalanx of the 5th finger (HP:0004219)3.16367063
13Congenital, generalized hypertrichosis (HP:0004540)3.14261624
14Aplasia involving bones of the upper limbs (HP:0009823)3.13182358
15Aplasia of the phalanges of the hand (HP:0009802)3.13182358
16Aplasia involving bones of the extremities (HP:0009825)3.13182358
17Aplasia/hypoplasia of the uterus (HP:0008684)3.11462750
18Ridged nail (HP:0001807)3.08638746
19Vacuolated lymphocytes (HP:0001922)3.00737713
20Broad face (HP:0000283)3.00224570
21Acute encephalopathy (HP:0006846)2.97135106
22Premature ovarian failure (HP:0008209)2.92853924
23Abnormality of the phalanges of the 5th finger (HP:0004213)2.84773892
24Pancreatic cysts (HP:0001737)2.83101621
25Abnormal umbilical cord blood vessels (HP:0011403)2.74819623
26Single umbilical artery (HP:0001195)2.74819623
27Abnormality of the fetal cardiovascular system (HP:0010948)2.74819623
28Pancreatic fibrosis (HP:0100732)2.66894318
29Supernumerary spleens (HP:0009799)2.65498175
30Spondylolisthesis (HP:0003302)2.63891562
31Concave nail (HP:0001598)2.62490046
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.62345531
33Decreased activity of mitochondrial respiratory chain (HP:0008972)2.62345531
34Acute necrotizing encephalopathy (HP:0006965)2.60407698
35Squamous cell carcinoma (HP:0002860)2.57583955
36Hypoparathyroidism (HP:0000829)2.53554197
37Hyperthyroidism (HP:0000836)2.52845361
38Ileus (HP:0002595)2.52439317
39Abnormal mitochondria in muscle tissue (HP:0008316)2.51406334
40Median cleft lip (HP:0000161)2.49716504
41Acute lymphatic leukemia (HP:0006721)2.49470391
42Neoplasm of the adrenal cortex (HP:0100641)2.44023745
43Metaphyseal dysplasia (HP:0100255)2.43298161
44Abnormality of the 2nd finger (HP:0004100)2.43198632
45Mitochondrial inheritance (HP:0001427)2.42722850
46Abnormality of the axillary hair (HP:0100134)2.41684109
47Abnormality of secondary sexual hair (HP:0009888)2.41684109
48Delayed myelination (HP:0012448)2.41435979
49Midline defect of the nose (HP:0004122)2.38243025
50Increased CSF lactate (HP:0002490)2.30397487
51Sparse lateral eyebrow (HP:0005338)2.30305678
52Progressive macrocephaly (HP:0004481)2.29689312
53Chromosomal breakage induced by crosslinking agents (HP:0003221)2.29141072
54Abnormality of pyrimidine metabolism (HP:0004353)2.28052979
55Abnormality of chromosome stability (HP:0003220)2.28043396
56Abnormality of the pons (HP:0007361)2.27682090
57Sparse eyelashes (HP:0000653)2.26301424
58Aplasia cutis congenita (HP:0001057)2.24202835
59Cerebral hypomyelination (HP:0006808)2.21962168
60Short femoral neck (HP:0100864)2.21798143
61Hypoplasia of the pons (HP:0012110)2.21768869
62Hepatocellular necrosis (HP:0001404)2.20716459
63Increased serum lactate (HP:0002151)2.20203087
64Abnormality of the middle phalanges of the toes (HP:0010183)2.19987337
65Type I transferrin isoform profile (HP:0003642)2.17716012
66Abnormality of lateral ventricle (HP:0030047)2.16876860
67Abnormality of subcutaneous fat tissue (HP:0001001)2.12741403
68Truncus arteriosus (HP:0001660)2.11538849
69Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.11444357
70Abnormality of the frontal sinuses (HP:0002687)2.10611683
71Patellar aplasia (HP:0006443)2.06092648
72Abnormality of the parathyroid morphology (HP:0011766)2.04389967
73Abnormality of T cell physiology (HP:0011840)2.02857057
74Cutaneous melanoma (HP:0012056)2.02717469
75Breast hypoplasia (HP:0003187)2.02692309
76Aplasia/Hypoplasia of the sacrum (HP:0008517)2.01197480
77Epiphyseal stippling (HP:0010655)1.98254401
78Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.97694692
79Abnormality of the pupil (HP:0000615)1.97467621
80Chromsome breakage (HP:0040012)1.97392186
81Aplasia/Hypoplasia of the patella (HP:0006498)1.96346595
82Hepatic necrosis (HP:0002605)1.95843025
83Tinnitus (HP:0000360)1.93473832
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.93017320
85Abnormality of alanine metabolism (HP:0010916)1.93017320
86Hyperalaninemia (HP:0003348)1.93017320
87Short tibia (HP:0005736)1.92090225
88Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.91674247
89Abnormality of the preputium (HP:0100587)1.90932001
90Bone marrow hypocellularity (HP:0005528)1.90660252
91Abnormality of the umbilical cord (HP:0010881)1.89967419
92Cerebral edema (HP:0002181)1.89933636
93Asplenia (HP:0001746)1.88981792
94Adactyly (HP:0009776)1.85944129
95Fair hair (HP:0002286)1.85674090
96Meckel diverticulum (HP:0002245)1.82038370
97Abnormality of the renal collecting system (HP:0004742)1.81931561
98Lactic acidosis (HP:0003128)1.80316218
99Adenoma sebaceum (HP:0009720)1.80200683
100Angiofibromas (HP:0010615)1.80200683

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK35.50446604
2ACVR1B4.35776320
3PLK24.25087305
4BMPR1B4.20722429
5WNK43.25926474
6TRIM282.88966288
7EIF2AK12.78712442
8FRK2.76129214
9FLT32.65489193
10SIK32.63677031
11MAPKAPK32.52367850
12PRKCI2.43013152
13MAP3K32.38248939
14CDC72.37170768
15EEF2K2.36060826
16MST42.34648542
17TGFBR12.05827354
18EIF2AK31.86896942
19SCYL21.80170350
20DAPK11.76859272
21SRPK11.71152481
22TTK1.66337864
23STK161.58549315
24EPHA21.49682797
25MAPK131.44079148
26BCR1.40193976
27BUB11.33413730
28RPS6KB21.31092458
29PKN21.29004769
30NEK21.19676763
31IRAK31.10766324
32ERBB31.00532587
33CDK30.98936423
34NME10.93623445
35CCNB10.93426198
36NEK10.89254876
37CSNK1E0.85510401
38MAPK120.84413630
39PLK10.84257967
40CHEK20.82511957
41CSNK1A10.79771049
42ATR0.79753488
43PLK30.78877847
44BRD40.77490635
45PLK40.74562199
46WEE10.72822426
47TRIB30.67837997
48ERBB40.66901687
49AKT20.65712057
50MST1R0.64738789
51ZAK0.60850175
52AURKB0.58667292
53ATM0.57136558
54CSNK2A20.55333651
55TRPM70.54944348
56WNK10.53391886
57TEC0.52208474
58STK40.51278546
59AURKA0.49408588
60CDK20.48758668
61BMPR20.48049232
62PBK0.46949641
63ARAF0.45220284
64CDK10.44185985
65KSR10.43166763
66BRAF0.43021184
67TLK10.42748242
68JAK30.42460006
69CHEK10.41471936
70GRK10.41160188
71LRRK20.40980811
72SGK10.39372902
73NME20.38028031
74MAPKAPK50.36295767
75BRSK10.36291994
76ALK0.36028647
77MAPK110.32134636
78FGFR20.32036373
79PRKACB0.31899115
80TNK20.31280778
81CSNK2A10.30648294
82PAK40.29954919
83PRKD30.29841272
84TSSK60.29293832
85CSNK1D0.29260481
86BRSK20.28036237
87MAP3K130.27311767
88BCKDK0.25526383
89PKN10.25298911
90PDK10.23058073
91EIF2AK20.21316879
92PIM20.20193936
93TBK10.20192540
94MAP2K10.19628498
95MAPKAPK20.19186132
96MAP3K80.18401152
97EGFR0.17889408
98GSK3B0.17670111
99PASK0.17369730
100CDK70.16875809

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.90382540
2Non-homologous end-joining_Homo sapiens_hsa034503.58040185
3Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.28396185
4Drug metabolism - other enzymes_Homo sapiens_hsa009833.06957612
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.05667530
6Proteasome_Homo sapiens_hsa030502.83043929
7Homologous recombination_Homo sapiens_hsa034402.69905685
8Mismatch repair_Homo sapiens_hsa034302.61066394
9Nucleotide excision repair_Homo sapiens_hsa034202.53918011
10Oxidative phosphorylation_Homo sapiens_hsa001902.41640942
11One carbon pool by folate_Homo sapiens_hsa006702.24360655
12RNA transport_Homo sapiens_hsa030132.15365773
13Pyrimidine metabolism_Homo sapiens_hsa002402.14482836
14Parkinsons disease_Homo sapiens_hsa050122.10577684
15Other glycan degradation_Homo sapiens_hsa005112.03376571
16Ribosome_Homo sapiens_hsa030102.00542970
17Fanconi anemia pathway_Homo sapiens_hsa034601.95629791
18Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.89053406
19Base excision repair_Homo sapiens_hsa034101.85784580
20Spliceosome_Homo sapiens_hsa030401.76262868
21RNA polymerase_Homo sapiens_hsa030201.73550277
22Fructose and mannose metabolism_Homo sapiens_hsa000511.73349536
23RNA degradation_Homo sapiens_hsa030181.67760414
24mRNA surveillance pathway_Homo sapiens_hsa030151.57672532
25Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.53240186
26Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.43452469
27Basal transcription factors_Homo sapiens_hsa030221.38442116
28Peroxisome_Homo sapiens_hsa041461.35567309
29Steroid biosynthesis_Homo sapiens_hsa001001.33622410
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32873865
31Chemical carcinogenesis_Homo sapiens_hsa052041.29728431
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27809124
33Steroid hormone biosynthesis_Homo sapiens_hsa001401.27134031
34Cell cycle_Homo sapiens_hsa041101.26985599
35Pentose and glucuronate interconversions_Homo sapiens_hsa000401.23228244
36Glutathione metabolism_Homo sapiens_hsa004801.20666005
37beta-Alanine metabolism_Homo sapiens_hsa004101.17253232
38Olfactory transduction_Homo sapiens_hsa047401.16863537
39Sulfur metabolism_Homo sapiens_hsa009201.15661809
40Protein export_Homo sapiens_hsa030601.14760976
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.14126194
42Alzheimers disease_Homo sapiens_hsa050101.12978348
43Galactose metabolism_Homo sapiens_hsa000521.12236226
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.06419100
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.06139690
46Huntingtons disease_Homo sapiens_hsa050161.02653983
47Selenocompound metabolism_Homo sapiens_hsa004500.97673276
48Starch and sucrose metabolism_Homo sapiens_hsa005000.97087391
49Purine metabolism_Homo sapiens_hsa002300.93073025
50Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92442094
51Retinol metabolism_Homo sapiens_hsa008300.92336019
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.91727621
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89872543
54Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86640049
55Propanoate metabolism_Homo sapiens_hsa006400.85092016
56Pentose phosphate pathway_Homo sapiens_hsa000300.80779891
57p53 signaling pathway_Homo sapiens_hsa041150.80099198
58Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80011755
59Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78851035
60N-Glycan biosynthesis_Homo sapiens_hsa005100.77526964
61Sulfur relay system_Homo sapiens_hsa041220.76772502
62Metabolic pathways_Homo sapiens_hsa011000.75054169
63Pyruvate metabolism_Homo sapiens_hsa006200.74443150
64Butanoate metabolism_Homo sapiens_hsa006500.74362031
65Biosynthesis of amino acids_Homo sapiens_hsa012300.64434023
66Vitamin B6 metabolism_Homo sapiens_hsa007500.64265628
67Tyrosine metabolism_Homo sapiens_hsa003500.64219660
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62638072
69Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62048380
70Caffeine metabolism_Homo sapiens_hsa002320.61643873
71Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.61248088
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61224389
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58567451
74Collecting duct acid secretion_Homo sapiens_hsa049660.57074410
75Ether lipid metabolism_Homo sapiens_hsa005650.47989588
76Fatty acid degradation_Homo sapiens_hsa000710.45556625
77Intestinal immune network for IgA production_Homo sapiens_hsa046720.43302889
78Oocyte meiosis_Homo sapiens_hsa041140.42577361
79Carbon metabolism_Homo sapiens_hsa012000.41334270
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.40799482
81Fatty acid metabolism_Homo sapiens_hsa012120.40790576
82Phenylalanine metabolism_Homo sapiens_hsa003600.36332325
83Central carbon metabolism in cancer_Homo sapiens_hsa052300.35412688
84Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.35246789
85Asthma_Homo sapiens_hsa053100.33839774
86Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31895940
87Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.31765815
88Regulation of autophagy_Homo sapiens_hsa041400.31519141
89Folate biosynthesis_Homo sapiens_hsa007900.27384396
90mTOR signaling pathway_Homo sapiens_hsa041500.26014560
91Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.25588188
92Mineral absorption_Homo sapiens_hsa049780.24700724
93Arginine and proline metabolism_Homo sapiens_hsa003300.24489338
94Small cell lung cancer_Homo sapiens_hsa052220.23481865
95Cardiac muscle contraction_Homo sapiens_hsa042600.18905568
96TGF-beta signaling pathway_Homo sapiens_hsa043500.18581206
97Non-small cell lung cancer_Homo sapiens_hsa052230.16168633
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.14267460
99Primary immunodeficiency_Homo sapiens_hsa053400.13103648
100Fatty acid elongation_Homo sapiens_hsa000620.12772176

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »