CROCC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.35814118
2epithelial cilium movement (GO:0003351)8.14121679
3axoneme assembly (GO:0035082)6.50262395
4left/right pattern formation (GO:0060972)6.28012320
5synaptic vesicle maturation (GO:0016188)5.92643100
6regulation of short-term neuronal synaptic plasticity (GO:0048172)5.76992625
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.65704758
8locomotory exploration behavior (GO:0035641)5.34002654
9lung epithelium development (GO:0060428)5.03550204
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.01416362
11vitamin transmembrane transport (GO:0035461)4.87623838
12ventricular system development (GO:0021591)4.81112398
13tolerance induction (GO:0002507)4.67629753
14establishment of apical/basal cell polarity (GO:0035089)4.66913456
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.65955265
16left/right axis specification (GO:0070986)4.56214066
17primary alcohol catabolic process (GO:0034310)4.42410221
18microtubule bundle formation (GO:0001578)4.39827905
19regulation of cilium movement (GO:0003352)4.16801683
20ethanol metabolic process (GO:0006067)4.16148830
21synaptic vesicle exocytosis (GO:0016079)4.07802415
22positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.06642529
23layer formation in cerebral cortex (GO:0021819)4.03730647
24regulation of synaptic vesicle exocytosis (GO:2000300)4.03374556
25vocalization behavior (GO:0071625)3.97217763
26negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.97013729
27sodium ion export (GO:0071436)3.96533558
28regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.94759407
29regulation of synapse structural plasticity (GO:0051823)3.93459145
30regulation of interleukin-5 production (GO:0032674)3.92691004
31regulation of glutamate receptor signaling pathway (GO:1900449)3.91033662
32positive regulation of tolerance induction (GO:0002645)3.89986873
33establishment of monopolar cell polarity (GO:0061162)3.87242465
34establishment or maintenance of monopolar cell polarity (GO:0061339)3.87242465
35planar cell polarity pathway involved in neural tube closure (GO:0090179)3.86552240
36negative regulation of cytosolic calcium ion concentration (GO:0051481)3.80561207
37regulation of interleukin-13 production (GO:0032656)3.80515529
38negative regulation of immunoglobulin mediated immune response (GO:0002890)3.80341386
39negative regulation of B cell mediated immunity (GO:0002713)3.80341386
40regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.77817880
41regulation of neuronal synaptic plasticity (GO:0048168)3.75947011
42cellular potassium ion homeostasis (GO:0030007)3.74158263
43G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.73087166
44glutamate secretion (GO:0014047)3.73025319
45protein localization to synapse (GO:0035418)3.69606313
46dendritic spine morphogenesis (GO:0060997)3.68675455
47regulation of long-term neuronal synaptic plasticity (GO:0048169)3.60944120
48prepulse inhibition (GO:0060134)3.60171565
49glomerular epithelial cell development (GO:0072310)3.57543827
50neurotransmitter secretion (GO:0007269)3.56400697
51neuromuscular process controlling balance (GO:0050885)3.55431350
52neuronal ion channel clustering (GO:0045161)3.53531831
53retinal rod cell development (GO:0046548)3.53106259
54positive regulation of synapse maturation (GO:0090129)3.52482744
55mannose metabolic process (GO:0006013)3.50804658
56regulation of synaptic vesicle transport (GO:1902803)3.49427090
57regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.46437275
58cilium organization (GO:0044782)3.46043638
59exploration behavior (GO:0035640)3.43617576
60dopamine receptor signaling pathway (GO:0007212)3.41103273
61cilium assembly (GO:0042384)3.40266339
62intraciliary transport (GO:0042073)3.38220371
63positive regulation of smoothened signaling pathway (GO:0045880)3.36089220
64regulation of clathrin-mediated endocytosis (GO:2000369)3.35708181
65striatum development (GO:0021756)3.34966059
66negative regulation of inclusion body assembly (GO:0090084)3.33831378
67auditory behavior (GO:0031223)3.31237638
68cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.28319625
69positive regulation of membrane potential (GO:0045838)3.27919636
70rhodopsin mediated signaling pathway (GO:0016056)3.22152739
71semaphorin-plexin signaling pathway (GO:0071526)3.21939158
72cell communication by electrical coupling (GO:0010644)3.21748340
73histone H3-K36 demethylation (GO:0070544)3.19492061
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.17743358
75positive regulation of synaptic transmission, GABAergic (GO:0032230)3.17559754
76positive regulation of neurotransmitter transport (GO:0051590)3.16722115
77photoreceptor cell development (GO:0042461)3.16332952
78neurotransmitter-gated ion channel clustering (GO:0072578)3.15533467
79regulation of rhodopsin mediated signaling pathway (GO:0022400)3.15430972
80ethanol oxidation (GO:0006069)3.14501337
81long-term memory (GO:0007616)3.13670371
82synaptic vesicle endocytosis (GO:0048488)3.13144781
83pre-miRNA processing (GO:0031054)3.12729837
84activation of protein kinase A activity (GO:0034199)3.12041753
85regulation of germinal center formation (GO:0002634)3.10906493
86membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.10785472
87establishment of planar polarity (GO:0001736)3.10529133
88establishment of tissue polarity (GO:0007164)3.10529133
89regulation of tolerance induction (GO:0002643)3.09906441
90lateral sprouting from an epithelium (GO:0060601)3.09820392
91one-carbon compound transport (GO:0019755)3.09170368
92retinal cone cell development (GO:0046549)3.08124034
93positive regulation of dendritic spine morphogenesis (GO:0061003)3.04989250
94microtubule-based movement (GO:0007018)3.04771865
95ionotropic glutamate receptor signaling pathway (GO:0035235)3.03939835
96cytoskeletal anchoring at plasma membrane (GO:0007016)3.02140988
97synaptic transmission, glutamatergic (GO:0035249)3.01944253
98regulation of dendritic spine morphogenesis (GO:0061001)3.00381627
99membrane hyperpolarization (GO:0060081)2.99839454
100neuromuscular process controlling posture (GO:0050884)2.98732071
101regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96801000
102adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.94546342
103regulation of ARF GTPase activity (GO:0032312)2.93950121
104response to auditory stimulus (GO:0010996)2.93596466
105eye photoreceptor cell development (GO:0042462)2.92723065
106negative regulation of erythrocyte differentiation (GO:0045647)2.92052327
107cell migration in hindbrain (GO:0021535)2.91969823
108potassium ion homeostasis (GO:0055075)2.90203585
109regulation of postsynaptic membrane potential (GO:0060078)2.90046803
110neurotransmitter transport (GO:0006836)2.89976441
111regulation of ARF protein signal transduction (GO:0032012)2.89861082
112regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.89477190
113ear development (GO:0043583)2.88705219
114neuron-neuron synaptic transmission (GO:0007270)2.88265156
115sperm capacitation (GO:0048240)2.86870533
116synaptic transmission, dopaminergic (GO:0001963)2.85746919
117diterpenoid biosynthetic process (GO:0016102)2.85383529
118negative regulation of T cell differentiation in thymus (GO:0033085)2.84967163
119cerebellar Purkinje cell differentiation (GO:0021702)2.82391127
120proline transport (GO:0015824)2.81810161
121potassium ion import (GO:0010107)2.80292543
122response to xenobiotic stimulus (GO:0009410)2.79348916
123chemosensory behavior (GO:0007635)2.78475505
124regulation of synaptic plasticity (GO:0048167)2.78000597
125establishment of nucleus localization (GO:0040023)2.75823389
126apical protein localization (GO:0045176)2.75197961
127innervation (GO:0060384)2.74188724
128establishment or maintenance of bipolar cell polarity (GO:0061245)2.73733430
129establishment or maintenance of apical/basal cell polarity (GO:0035088)2.73733430
130behavioral fear response (GO:0001662)2.73326550
131behavioral defense response (GO:0002209)2.73326550
132cellular component assembly involved in morphogenesis (GO:0010927)2.73292969
133regulation of apoptotic cell clearance (GO:2000425)2.72436206
134membrane depolarization during action potential (GO:0086010)2.72146548
135thymic T cell selection (GO:0045061)2.71511854
136regulation of neurotransmitter secretion (GO:0046928)2.69395589
137mating behavior (GO:0007617)2.69247322
138cytoplasmic microtubule organization (GO:0031122)2.69239478
139positive regulation of Rap GTPase activity (GO:0032854)2.69213342
140negative regulation of humoral immune response (GO:0002921)2.69184757
141positive thymic T cell selection (GO:0045059)2.68482051
142membrane repolarization (GO:0086009)2.67874782
143positive regulation of neurotransmitter secretion (GO:0001956)2.67408637
144regulation of Rap GTPase activity (GO:0032317)2.66966205
145glycine transport (GO:0015816)2.66956820
146cell projection assembly (GO:0030031)2.66664900
147cerebellar Purkinje cell layer development (GO:0021680)2.65019433
148regulation of microtubule-based movement (GO:0060632)2.64813922
149glutamate receptor signaling pathway (GO:0007215)2.64485632
150regulation of synaptic transmission, glutamatergic (GO:0051966)2.63727729
151neuromuscular process (GO:0050905)2.63570855
152embryonic camera-type eye development (GO:0031076)2.63475098
153centriole assembly (GO:0098534)2.62999637
154regulation of voltage-gated calcium channel activity (GO:1901385)2.62369683
155transmission of nerve impulse (GO:0019226)2.62362282
156regulation of cilium assembly (GO:1902017)2.61968973
157dendritic spine organization (GO:0097061)2.60930670
158vesicle transport along microtubule (GO:0047496)2.59874044
159regulation of vesicle fusion (GO:0031338)2.58602686
160positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.58483265
161negative regulation of myotube differentiation (GO:0010832)2.58483061
162regulation of female receptivity (GO:0045924)2.58437627
163regulation of neurotransmitter transport (GO:0051588)2.58195025
164neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.57203247
165regulation of gamma-delta T cell differentiation (GO:0045586)2.54886688
166protein localization to cilium (GO:0061512)2.54436103
167dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.54248118
168camera-type eye morphogenesis (GO:0048593)2.53683719
169histone lysine demethylation (GO:0070076)2.53408512
170histone H3-K9 demethylation (GO:0033169)2.52625001
171regulation of response to osmotic stress (GO:0047484)2.51472964
172lateral ventricle development (GO:0021670)2.51195551
173negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.48216202
174negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.42682238
175Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.42048402
176cell-cell junction maintenance (GO:0045217)2.41633344
177epithelial cell differentiation involved in prostate gland development (GO:0060742)2.41564917
178filopodium assembly (GO:0046847)2.40712646
179positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.37943167
180regulation of interleukin-4 production (GO:0032673)2.37659434
181pyrimidine-containing compound transmembrane transport (GO:0072531)2.37528949
182peptidyl-tyrosine autophosphorylation (GO:0038083)2.35405418
183regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.34800752
184histone demethylation (GO:0016577)2.34007852
185regulation of smoothened signaling pathway (GO:0008589)2.33009726
186histone H3 deacetylation (GO:0070932)2.31135748
187phosphatidylcholine biosynthetic process (GO:0006656)2.29282156
188regulation of microtubule depolymerization (GO:0031114)2.27628272
189phosphatidylethanolamine biosynthetic process (GO:0006646)2.26866722
190retinoic acid metabolic process (GO:0042573)2.26520169
191regulation of establishment of planar polarity (GO:0090175)2.23913373
192histone H4 deacetylation (GO:0070933)2.23371790
193regulation of collateral sprouting (GO:0048670)2.23050707
194regulation of inclusion body assembly (GO:0090083)2.20859521
195axonemal dynein complex assembly (GO:0070286)14.3706547
196cilium or flagellum-dependent cell motility (GO:0001539)12.8122815
197motile cilium assembly (GO:0044458)10.3856275
198cilium movement (GO:0003341)10.2159522

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.78553175
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.62635187
3EZH2_22144423_ChIP-Seq_EOC_Human3.60801574
4* RARB_27405468_Chip-Seq_BRAIN_Mouse3.41897529
5DROSHA_22980978_ChIP-Seq_HELA_Human2.69452358
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.63762374
7ZFP281_18757296_ChIP-ChIP_E14_Mouse2.54201257
8SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.52041275
9REST_21632747_ChIP-Seq_MESCs_Mouse2.42590162
10ERG_21242973_ChIP-ChIP_JURKAT_Human2.35438787
11ZFP281_27345836_Chip-Seq_ESCs_Mouse2.35282194
12* KDM2B_26808549_Chip-Seq_K562_Human2.34511661
13MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.33754252
14ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.29107438
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.28584252
16IKZF1_21737484_ChIP-ChIP_HCT116_Human2.25935769
17* REST_18959480_ChIP-ChIP_MESCs_Mouse2.19510692
18VDR_21846776_ChIP-Seq_THP-1_Human2.17973149
19EZH2_18974828_ChIP-Seq_MESCs_Mouse2.09216775
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.09216775
21* CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.04899712
22* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.02835961
23JARID2_20075857_ChIP-Seq_MESCs_Mouse2.02073199
24SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.97458288
25ELK3_25401928_ChIP-Seq_HUVEC_Human1.96133578
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.95498358
27* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.93173134
28* KDM2B_26808549_Chip-Seq_DND41_Human1.90586425
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.88906397
30DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.88643350
31SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.87849398
32SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87309727
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.87092850
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.85260963
35WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.84239996
36* RUNX1_27514584_Chip-Seq_MCF-7_Human1.80864407
37RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.80608445
38* SA1_27219007_Chip-Seq_ERYTHROID_Human1.78889233
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.76972798
40* LXR_22292898_ChIP-Seq_THP-1_Human1.75980319
41ESR2_21235772_ChIP-Seq_MCF-7_Human1.73222982
42RARG_19884340_ChIP-ChIP_MEFs_Mouse1.71197061
43DNAJC2_21179169_ChIP-ChIP_NT2_Human1.69366408
44EZH2_27304074_Chip-Seq_ESCs_Mouse1.68421746
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.66985604
46* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.64568469
47SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.64271112
48* KDM2B_26808549_Chip-Seq_JURKAT_Human1.63911172
49TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63062273
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.60447523
51RING1B_27294783_Chip-Seq_NPCs_Mouse1.60403477
52* ELF1_20517297_ChIP-Seq_JURKAT_Human1.60351602
53TP63_22573176_ChIP-Seq_HFKS_Human1.59385044
54E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52894784
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.52664357
56TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.52564357
57SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.52533706
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.51368346
59MYC_22102868_ChIP-Seq_BL_Human1.51205397
60MAF_26560356_Chip-Seq_TH1_Human1.50556614
61* CTCF_27219007_Chip-Seq_Bcells_Human1.49860099
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.48867966
63* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.47335904
64SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46934768
65CREB1_26743006_Chip-Seq_LNCaP_Human1.45918619
66VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43299534
67SMC4_20622854_ChIP-Seq_HELA_Human1.42483726
68RING1B_27294783_Chip-Seq_ESCs_Mouse1.41655586
69WT1_25993318_ChIP-Seq_PODOCYTE_Human1.40997671
70* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.39413693
71SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.38809675
72* PHF8_20622854_ChIP-Seq_HELA_Human1.36832301
73* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.35829425
74PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.35441527
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.35317439
76TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.35258138
77TCF7_22412390_ChIP-Seq_EML_Mouse1.35221535
78KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.33694340
79BCOR_27268052_Chip-Seq_Bcells_Human1.32609868
80UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.31622156
81* UTX_26944678_Chip-Seq_JUKART_Human1.30995931
82BCL6_27268052_Chip-Seq_Bcells_Human1.30674774
83* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30288309
84VDR_24763502_ChIP-Seq_THP-1_Human1.30230528
85GATA1_19941827_ChIP-Seq_MEL_Mouse1.29277916
86* MAF_26560356_Chip-Seq_TH2_Human1.27863160
87STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.26847363
88CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.26525545
89AR_19668381_ChIP-Seq_PC3_Human1.26022377
90ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.25782664
91SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.22835359
92NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.22565638
93* TET1_21490601_ChIP-Seq_MESCs_Mouse1.20089353
94OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.18832156
95* SA1_27219007_Chip-Seq_Bcells_Human1.18156779
96EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.17999991
97P68_20966046_ChIP-Seq_HELA_Human1.17185199
98* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16298877
99SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16271651
100ESR1_15608294_ChIP-ChIP_MCF-7_Human1.15215400
101* TET1_21451524_ChIP-Seq_MESCs_Mouse1.15047816
102OCT4_19829295_ChIP-Seq_ESCs_Human1.15011526
103GATA1_19941826_ChIP-Seq_K562_Human1.14121986
104* E2F1_20622854_ChIP-Seq_HELA_Human1.13487746
105RUNX1_22412390_ChIP-Seq_EML_Mouse1.11657238
106RARB_24833708_ChIP-Seq_LIVER_Mouse1.11560690
107CTCF_20526341_ChIP-Seq_ESCs_Human1.11494576
108* TP53_22127205_ChIP-Seq_IMR90_Human1.10889606
109EED_16625203_ChIP-ChIP_MESCs_Mouse1.10680166
110* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.08324087
111POU5F1_16518401_ChIP-PET_MESCs_Mouse1.06391608
112MYC_27129775_Chip-Seq_CORNEA_Mouse1.06338098
113SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06214742
114YY1_22570637_ChIP-Seq_MALME-3M_Human1.05946769
115KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.05628619
116ESR1_20079471_ChIP-ChIP_T-47D_Human1.03114375
117ESR1_21235772_ChIP-Seq_MCF-7_Human1.02742767
118NCOR1_26117541_ChIP-Seq_K562_Human1.02526993
119P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02509802
120P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00111852
121RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99927288
122KLF4_19829295_ChIP-Seq_ESCs_Human0.99783132
123* KLF5_25053715_ChIP-Seq_YYC3_Human0.99491137
124STAT1_20625510_ChIP-Seq_HELA_Human0.99228712
125KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97862347
126KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97862347
127KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97862347
128SMAD3_21741376_ChIP-Seq_HESCs_Human0.97447659
129GBX2_23144817_ChIP-Seq_PC3_Human0.96824116
130SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96646698
131NFIB_24661679_ChIP-Seq_LUNG_Mouse0.96226315
132CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.96193365
133DPY_21335234_ChIP-Seq_ESCs_Mouse0.95918745
134* TP53_23651856_ChIP-Seq_MEFs_Mouse0.95900693
135SOX2_27498859_Chip-Seq_STOMACH_Mouse0.95112870
136CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94914807
137NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94609337
138YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94572777
139* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.94524590
140TP63_17297297_ChIP-ChIP_HaCaT_Human0.93870701
141NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.93654701
142SPI1_23127762_ChIP-Seq_K562_Human0.93390370
143ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93028854
144NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.92572926
145PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92568347
146RACK7_27058665_Chip-Seq_MCF-7_Human0.92490752
147E2F1_17053090_ChIP-ChIP_MCF-7_Human0.92444500
148PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.92121686
149GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.91417488
150SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.89979386
151ISL1_27105846_Chip-Seq_CPCs_Mouse0.87701444
152MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.87177164
153SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.86478557
154SOX3_22085726_ChIP-Seq_NPCs_Mouse0.86284589
155SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86274034

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.30272057
2MP0002822_catalepsy4.08775976
3MP0002132_abnormal_respiratory_system3.70678925
4MP0005551_abnormal_eye_electrophysiolog3.42609343
5MP0002249_abnormal_larynx_morphology3.40248475
6MP0003878_abnormal_ear_physiology3.34080265
7MP0005377_hearing/vestibular/ear_phenot3.34080265
8MP0000566_synostosis3.28710680
9MP0003635_abnormal_synaptic_transmissio3.21778176
10MP0001849_ear_inflammation3.16488372
11MP0006072_abnormal_retinal_apoptosis2.96697500
12MP0003283_abnormal_digestive_organ2.77405349
13MP0008875_abnormal_xenobiotic_pharmacok2.72531274
14MP0002653_abnormal_ependyma_morphology2.65571285
15MP0005423_abnormal_somatic_nervous2.62891271
16MP0005253_abnormal_eye_physiology2.54783441
17MP0002063_abnormal_learning/memory/cond2.53463760
18MP0003880_abnormal_central_pattern2.48311988
19MP0009278_abnormal_bone_marrow2.47164053
20MP0009745_abnormal_behavioral_response2.40733681
21MP0004270_analgesia2.38721932
22MP0003011_delayed_dark_adaptation2.38562117
23MP0002064_seizures2.25329787
24MP0002909_abnormal_adrenal_gland2.15173254
25MP0009046_muscle_twitch2.13906260
26MP0002572_abnormal_emotion/affect_behav2.00401854
27MP0001486_abnormal_startle_reflex2.00248886
28MP0006292_abnormal_olfactory_placode1.97578394
29MP0003787_abnormal_imprinting1.94605764
30MP0008961_abnormal_basal_metabolism1.94408582
31MP0004885_abnormal_endolymph1.93882319
32MP0004858_abnormal_nervous_system1.92260210
33MP0004381_abnormal_hair_follicle1.85547212
34MP0003763_abnormal_thymus_physiology1.85454440
35MP0005409_darkened_coat_color1.78733773
36MP0002277_abnormal_respiratory_mucosa1.77262214
37MP0002272_abnormal_nervous_system1.76918455
38MP0003136_yellow_coat_color1.75773542
39MP0003122_maternal_imprinting1.69598957
40MP0005394_taste/olfaction_phenotype1.63167907
41MP0005499_abnormal_olfactory_system1.63167907
42MP0004811_abnormal_neuron_physiology1.57944748
43* MP0002882_abnormal_neuron_morphology1.51752527
44MP0002734_abnormal_mechanical_nocicepti1.51199184
45MP0009780_abnormal_chondrocyte_physiolo1.49252022
46MP0004233_abnormal_muscle_weight1.47538935
47MP0003303_peritoneal_inflammation1.46306587
48MP0008789_abnormal_olfactory_epithelium1.44875776
49* MP0005195_abnormal_posterior_eye1.44426876
50MP0000955_abnormal_spinal_cord1.43306549
51MP0001984_abnormal_olfaction1.42007509
52MP0005391_vision/eye_phenotype1.41793973
53MP0001502_abnormal_circadian_rhythm1.38083337
54MP0005503_abnormal_tendon_morphology1.37786021
55MP0000569_abnormal_digit_pigmentation1.36557052
56MP0002184_abnormal_innervation1.34396154
57MP0010030_abnormal_orbit_morphology1.33474021
58MP0002090_abnormal_vision1.31812570
59* MP0002229_neurodegeneration1.28408539
60MP0001968_abnormal_touch/_nociception1.27908409
61MP0008569_lethality_at_weaning1.27822161
62MP0003123_paternal_imprinting1.26984789
63MP0002116_abnormal_craniofacial_bone1.26821725
64MP0002557_abnormal_social/conspecific_i1.26501559
65MP0003279_aneurysm1.22174506
66MP0002168_other_aberrant_phenotype1.22050038
67MP0001501_abnormal_sleep_pattern1.21853525
68MP0000049_abnormal_middle_ear1.21342948
69MP0000778_abnormal_nervous_system1.21156473
70MP0004145_abnormal_muscle_electrophysio1.21013111
71MP0004924_abnormal_behavior1.20788183
72MP0005386_behavior/neurological_phenoty1.20788183
73MP0003890_abnormal_embryonic-extraembry1.19824485
74MP0001324_abnormal_eye_pigmentation1.18903022
75MP0000681_abnormal_thyroid_gland1.18409915
76MP0003121_genomic_imprinting1.16672023
77MP0002932_abnormal_joint_morphology1.16147939
78MP0003453_abnormal_keratinocyte_physiol1.15017809
79MP0003938_abnormal_ear_development1.14925840
80MP0010155_abnormal_intestine_physiology1.14362192
81* MP0002752_abnormal_somatic_nervous1.14054035
82MP0001346_abnormal_lacrimal_gland1.14052638
83MP0005623_abnormal_meninges_morphology1.13658689
84MP0002152_abnormal_brain_morphology1.13647260
85MP0001970_abnormal_pain_threshold1.13261172
86MP0003436_decreased_susceptibility_to1.10744469
87MP0002733_abnormal_thermal_nociception1.10213270
88MP0002067_abnormal_sensory_capabilities1.09722183
89MP0003705_abnormal_hypodermis_morpholog1.09679121
90MP0009384_cardiac_valve_regurgitation1.08893204
91MP0005646_abnormal_pituitary_gland1.07112556
92MP0002066_abnormal_motor_capabilities/c1.03456060
93MP0003172_abnormal_lysosome_physiology1.01903537
94MP0003633_abnormal_nervous_system1.01191516
95MP0001958_emphysema0.99690989
96MP0001440_abnormal_grooming_behavior0.98762119
97MP0005666_abnormal_adipose_tissue0.97792470
98MP0000751_myopathy0.97302429
99MP0003879_abnormal_hair_cell0.97233718
100MP0003861_abnormal_nervous_system0.95342223
101MP0002933_joint_inflammation0.94065286
102MP0002282_abnormal_trachea_morphology0.93838432
103MP0005076_abnormal_cell_differentiation0.93666740
104MP0001270_distended_abdomen0.93028018
105MP0001299_abnormal_eye_distance/0.92523591
106MP0003119_abnormal_digestive_system0.92285048
107MP0000631_abnormal_neuroendocrine_gland0.92133271
108MP0005167_abnormal_blood-brain_barrier0.92032634
109MP0004043_abnormal_pH_regulation0.91933325
110MP0005058_abnormal_lysosome_morphology0.90959162
111MP0002234_abnormal_pharynx_morphology0.89638100
112MP0001765_abnormal_ion_homeostasis0.89382940
113MP0004133_heterotaxia0.88752253
114MP0004264_abnormal_extraembryonic_tissu0.86735429
115MP0002108_abnormal_muscle_morphology0.86082804
116MP0003634_abnormal_glial_cell0.85927269
117MP0003115_abnormal_respiratory_system0.85020758
118MP0004947_skin_inflammation0.84680851
119MP0003866_abnormal_defecation0.84378697
120MP0005375_adipose_tissue_phenotype0.83860645
121MP0002089_abnormal_postnatal_growth/wei0.82611420
122MP0002638_abnormal_pupillary_reflex0.81985275
123MP0002092_abnormal_eye_morphology0.81254576
124MP0000026_abnormal_inner_ear0.81127001
125MP0010234_abnormal_vibrissa_follicle0.81108151
126MP0000703_abnormal_thymus_morphology0.80316692
127MP0003631_nervous_system_phenotype0.80166304
128MP0008877_abnormal_DNA_methylation0.80110367
129MP0000733_abnormal_muscle_development0.79605779
130MP0004085_abnormal_heartbeat0.79501100
131MP0003075_altered_response_to0.79379696
132MP0009703_decreased_birth_body0.78057906
133MP0001293_anophthalmia0.77204633
134MP0000432_abnormal_head_morphology0.77066769
135MP0000537_abnormal_urethra_morphology0.75981096
136MP0000428_abnormal_craniofacial_morphol0.75916023
137MP0003045_fibrosis0.74436304
138MP0000678_abnormal_parathyroid_gland0.74240824
139MP0000534_abnormal_ureter_morphology0.73954482
140MP0005508_abnormal_skeleton_morphology0.73821133
141MP0005645_abnormal_hypothalamus_physiol0.72091856
142MP0002069_abnormal_eating/drinking_beha0.71963421
143MP0000858_altered_metastatic_potential0.70591669
144MP0005387_immune_system_phenotype0.69807985
145MP0001790_abnormal_immune_system0.69807985
146MP0002254_reproductive_system_inflammat0.69750486
147MP0008872_abnormal_physiological_respon0.69695118
148MP0002084_abnormal_developmental_patter0.69205714
149MP0002925_abnormal_cardiovascular_devel0.68633407
150MP0003329_amyloid_beta_deposits0.68278223
151MP0005248_abnormal_Harderian_gland0.68248403
152MP0005187_abnormal_penis_morphology0.68233246
153MP0000383_abnormal_hair_follicle0.67436984
154MP0004185_abnormal_adipocyte_glucose0.67189473
155MP0002998_abnormal_bone_remodeling0.67083205
156MP0003690_abnormal_glial_cell0.66662017
157MP0002697_abnormal_eye_size0.66464584
158MP0003137_abnormal_impulse_conducting0.65936165
159MP0003632_abnormal_nervous_system0.65928756
160MP0000013_abnormal_adipose_tissue0.65261510
161* MP0002405_respiratory_system_inflammati0.64470686
162MP0002233_abnormal_nose_morphology0.63966385
163MP0000003_abnormal_adipose_tissue0.63789461
164MP0002735_abnormal_chemical_nociception0.63568646
165MP0003091_abnormal_cell_migration0.62978765
166MP0001177_atelectasis0.62846562
167MP0008874_decreased_physiological_sensi0.62815275
168MP0004130_abnormal_muscle_cell0.61643700
169MP0005670_abnormal_white_adipose0.59942229
170MP0001963_abnormal_hearing_physiology0.59442662
171MP0008260_abnormal_autophagy0.59101437
172MP0004019_abnormal_vitamin_homeostasis0.58337611
173MP0009333_abnormal_splenocyte_physiolog0.58165106
174MP0000477_abnormal_intestine_morphology0.57898615

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.50389358
2Abnormal respiratory motile cilium morphology (HP:0005938)9.50389358
3Dynein arm defect of respiratory motile cilia (HP:0012255)9.18668050
4Absent/shortened dynein arms (HP:0200106)9.18668050
5Abnormal respiratory motile cilium physiology (HP:0012261)8.95442870
6Abnormal ciliary motility (HP:0012262)8.94219189
7Rhinitis (HP:0012384)8.02079035
8Chronic bronchitis (HP:0004469)6.54289500
9Nasal polyposis (HP:0100582)6.44188785
10Bronchiectasis (HP:0002110)6.19108089
11Congenital stationary night blindness (HP:0007642)5.76393899
12Abnormality of the nasal mucosa (HP:0000433)5.46933961
13Absent rod-and cone-mediated responses on ERG (HP:0007688)4.56151019
14Myokymia (HP:0002411)4.55172066
15Central scotoma (HP:0000603)4.45214527
16Bony spicule pigmentary retinopathy (HP:0007737)4.42318978
17Abnormal rod and cone electroretinograms (HP:0008323)4.35440939
18Pendular nystagmus (HP:0012043)4.10653845
19Abnormality of the lower motor neuron (HP:0002366)4.02500271
20Scotoma (HP:0000575)3.94295834
21Recurrent sinusitis (HP:0011108)3.73809031
22Obstructive sleep apnea (HP:0002870)3.73618914
23Recurrent otitis media (HP:0000403)3.71892790
24Bronchitis (HP:0012387)3.67430286
25Infertility (HP:0000789)3.64165577
26Male infertility (HP:0003251)3.62095310
27Atelectasis (HP:0100750)3.58616040
28Focal motor seizures (HP:0011153)3.35439081
29Visual hallucinations (HP:0002367)3.30068249
30Abnormality of macular pigmentation (HP:0008002)3.28615200
31Focal seizures (HP:0007359)3.26767701
32Chronic sinusitis (HP:0011109)3.23580685
33Occipital encephalocele (HP:0002085)3.17754148
34Severe visual impairment (HP:0001141)3.17339380
35Chorioretinal atrophy (HP:0000533)3.16246509
36Annular pancreas (HP:0001734)2.91966864
37Insomnia (HP:0100785)2.91131674
38Chronic otitis media (HP:0000389)2.85037141
39Posterior subcapsular cataract (HP:0007787)2.84355714
40Hyperacusis (HP:0010780)2.79095025
41Bell-shaped thorax (HP:0001591)2.77990196
42Decreased central vision (HP:0007663)2.77694446
43Type II diabetes mellitus (HP:0005978)2.74048204
44Abolished electroretinogram (ERG) (HP:0000550)2.73705675
45Epileptic encephalopathy (HP:0200134)2.68234444
46Pointed chin (HP:0000307)2.66510713
47Pigmentary retinal degeneration (HP:0001146)2.62013218
48Astrocytoma (HP:0009592)2.54099462
49Abnormality of the astrocytes (HP:0100707)2.54099462
50Depression (HP:0000716)2.51606439
51Ependymoma (HP:0002888)2.51276047
52Febrile seizures (HP:0002373)2.50576543
53Resting tremor (HP:0002322)2.49121163
54Ankyloglossia (HP:0010296)2.46960802
55Neoplasm of the heart (HP:0100544)2.46835332
56Dyschromatopsia (HP:0007641)2.44322605
57Macroorchidism (HP:0000053)2.43253220
58Elfin facies (HP:0004428)2.41728319
59Macular degeneration (HP:0000608)2.38761460
60Cerebral aneurysm (HP:0004944)2.38542690
61Upper limb amyotrophy (HP:0009129)2.34893155
62Distal upper limb amyotrophy (HP:0007149)2.34893155
63Action tremor (HP:0002345)2.34130585
64Renal duplication (HP:0000075)2.33810455
65Ankle clonus (HP:0011448)2.33783719
66Cystic liver disease (HP:0006706)2.33059567
67Dysdiadochokinesis (HP:0002075)2.29056520
68Absent frontal sinuses (HP:0002688)2.28389219
69Hyperactive renin-angiotensin system (HP:0000841)2.19507810
70Attenuation of retinal blood vessels (HP:0007843)2.17520779
71Stridor (HP:0010307)2.15208701
72Amblyopia (HP:0000646)2.11677782
73Supranuclear gaze palsy (HP:0000605)2.11075356
74Postural instability (HP:0002172)2.08667478
75Impaired smooth pursuit (HP:0007772)2.08049470
76Photophobia (HP:0000613)2.06625878
77True hermaphroditism (HP:0010459)2.05155229
78Absence seizures (HP:0002121)2.03926445
79Nephronophthisis (HP:0000090)2.03817814
80Abnormal social behavior (HP:0012433)2.02984271
81Impaired social interactions (HP:0000735)2.02984271
82Hand muscle atrophy (HP:0009130)2.01438883
83Hemiplegia (HP:0002301)2.00002441
84Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.1881862
85Hemiparesis (HP:0001269)1.99891050
86Progressive cerebellar ataxia (HP:0002073)1.99560189
87Obsessive-compulsive behavior (HP:0000722)1.98046714
88Renovascular hypertension (HP:0100817)1.97891127
89Abnormality of ocular smooth pursuit (HP:0000617)1.97844600
90Bronchomalacia (HP:0002780)1.96250291
91Neoplasm of the oral cavity (HP:0100649)1.95637640
92Pancreatic fibrosis (HP:0100732)1.95221722
93Overriding aorta (HP:0002623)1.92462268
94Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.92170645
95Broad face (HP:0000283)1.91609438
96Impaired vibration sensation in the lower limbs (HP:0002166)1.90615296
97Poor eye contact (HP:0000817)1.89684869
98Broad distal phalanx of finger (HP:0009836)1.87501082
99Ventricular fibrillation (HP:0001663)1.87459533
100Urinary bladder sphincter dysfunction (HP:0002839)1.85020712
101Glioma (HP:0009733)1.84343658
102Dialeptic seizures (HP:0011146)1.84230353
103Chronic hepatic failure (HP:0100626)1.84168729
104Dysmetric saccades (HP:0000641)1.82706084
105Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.82548556
106Abnormality of the aortic arch (HP:0012303)1.82199811
107Abnormality of oral frenula (HP:0000190)1.81921412
108Flat cornea (HP:0007720)1.81638661
109Generalized tonic-clonic seizures (HP:0002069)1.81210663
110Generalized hypotonia (HP:0001290)1.81179109
111Bowel diverticulosis (HP:0005222)1.80111546
112Aplasia/Hypoplasia of the spleen (HP:0010451)1.78171131
113Increased corneal curvature (HP:0100692)1.77258633
114Keratoconus (HP:0000563)1.77258633
115Genetic anticipation (HP:0003743)1.74611411
116Torticollis (HP:0000473)1.74031844
117Postaxial foot polydactyly (HP:0001830)1.73330220
118Truncal ataxia (HP:0002078)1.73052924
119Sleep apnea (HP:0010535)1.73015985
120Papilledema (HP:0001085)1.72465184
121Recurrent bronchitis (HP:0002837)1.70214577
122Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.68493267
123Constricted visual fields (HP:0001133)1.68462258
124Atonic seizures (HP:0010819)1.67232055
125Bradykinesia (HP:0002067)1.67012593
126Anxiety (HP:0000739)1.64071151
127Asplenia (HP:0001746)1.63846905
128Subcapsular cataract (HP:0000523)1.61266729
129Molar tooth sign on MRI (HP:0002419)1.61253000
130Abnormality of midbrain morphology (HP:0002418)1.61253000
131Hyperkalemia (HP:0002153)1.59781333
132Intention tremor (HP:0002080)1.59652951
133Hypercortisolism (HP:0001578)1.59024390
134Cervical subluxation (HP:0003308)1.58233139
135Vitreoretinal degeneration (HP:0000655)1.56710114
136Turricephaly (HP:0000262)1.56514605
137Abnormality of the fingertips (HP:0001211)1.56417033
138Choroideremia (HP:0001139)1.55950965
139Flat acetabular roof (HP:0003180)1.55874267
140Urinary urgency (HP:0000012)1.55169515
141Stereotypic behavior (HP:0000733)1.54867135
142Increased nuchal translucency (HP:0010880)1.54835456
143Horizontal nystagmus (HP:0000666)1.54188989
144Abnormality of the renal medulla (HP:0100957)1.53703825
145Neoplasm of striated muscle (HP:0009728)1.53422310
146Abnormal EKG (HP:0003115)1.52961369
147Gaze-evoked nystagmus (HP:0000640)1.52919121
148Megalencephaly (HP:0001355)1.52877890
149Dysmetria (HP:0001310)1.52365044
150Broad-based gait (HP:0002136)1.51716572
151Congenital hepatic fibrosis (HP:0002612)1.49324709
152Shallow orbits (HP:0000586)1.47493793
153Ulnar bowing (HP:0003031)1.47229461
154Broad metatarsal (HP:0001783)1.45940139
155Abnormal vertebral ossification (HP:0100569)1.45860224
156Metaphyseal cupping (HP:0003021)1.44892438
157Renal salt wasting (HP:0000127)1.44671799
158Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.44427385
159Short thorax (HP:0010306)1.40817300
160Anencephaly (HP:0002323)1.36311488
161Vertebral arch anomaly (HP:0008438)1.36143745
162Self-mutilation (HP:0000742)1.32864325
163Pancreatic cysts (HP:0001737)1.31531353
164Abnormality of the dental root (HP:0006486)1.29239677
165Taurodontia (HP:0000679)1.29239677
166Abnormality of permanent molar morphology (HP:0011071)1.29239677
167Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.29140370
168Abnormality of dentin (HP:0010299)1.28229624
169Decreased circulating renin level (HP:0003351)1.27745519
170Tubulointerstitial nephritis (HP:0001970)1.27383169
171Narrow chest (HP:0000774)1.25550686
172Nephropathy (HP:0000112)1.25499774
173Spinal muscular atrophy (HP:0007269)1.22816716
174Abnormality of molar (HP:0011077)1.21872050
175Abnormality of molar morphology (HP:0011070)1.21872050
176Abnormality of the frontal sinuses (HP:0002687)1.21072044
177Broad palm (HP:0001169)1.17095394
178Down-sloping shoulders (HP:0200021)1.15620476
179Colitis (HP:0002583)1.14934358
180Distal lower limb muscle weakness (HP:0009053)1.14325788
181Muscle fiber splitting (HP:0003555)1.14144272
182Optic nerve coloboma (HP:0000588)1.13140959
183Renal dysplasia (HP:0000110)1.13026628
184Nuclear cataract (HP:0100018)1.12102272
185Thin ribs (HP:0000883)1.10831759
186Dislocated radial head (HP:0003083)1.10727005
187Abnormality of the thoracic spine (HP:0100711)1.10605765
188Abnormality of the dental pulp (HP:0006479)1.10158113
189Thoracic kyphosis (HP:0002942)1.09881748
190Biconcave vertebral bodies (HP:0004586)1.09787939
191Polycystic kidney dysplasia (HP:0000113)1.09774672

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA43.97332589
2SMG13.42585478
3PRKD33.32554446
4MAP3K93.32078144
5NTRK33.06391102
6SIK22.63162594
7CDK122.37114942
8ICK2.24151418
9TYRO32.22642694
10NEK12.21053496
11SCYL22.18967132
12PAK62.14967975
13EPHA22.11039990
14MAP3K101.95174777
15DAPK21.87606702
16RIPK11.85761935
17NTRK21.84687791
18CAMKK11.83327156
19STK381.83270623
20MAP3K41.79488069
21KSR21.71245203
22MINK11.70427950
23PINK11.65395773
24ALK1.64218436
25NTRK11.61942972
26FGFR41.60044749
27SIK11.53668053
28EPHB11.52374488
29TRIB31.48111295
30MAP4K11.44030899
31ERN11.33818462
32UHMK11.33138657
33PDGFRA1.30984584
34DAPK11.30700418
35TAOK11.30105563
36FGFR21.29864723
37CSK1.29417749
38PRKD21.27079995
39NEK21.26709470
40MARK11.26006980
41PRKCH1.25297630
42KSR11.24038241
43NME11.19687458
44GRK11.19572280
45CDK51.18006460
46PKN21.16353541
47MARK21.15148852
48GRK51.12787711
49ZAP701.11899621
50CDC42BPA1.09954991
51PNCK1.09771031
52GRK61.09424386
53FES1.08573962
54CAMK1G1.07880355
55DDR21.05234916
56MAP2K31.00364260
57EEF2K0.96807371
58BMX0.96310429
59MAP3K20.95465856
60TYK20.95249861
61FGFR30.94379316
62STK110.94106988
63CAMK40.94064081
64HIPK20.92965047
65BTK0.88601285
66MAPK120.88368278
67RPS6KL10.83182559
68RPS6KC10.83182559
69MAP3K30.83050597
70MAP3K70.82298248
71MAP2K60.80959702
72TBK10.80133929
73PRPF4B0.78486002
74WNK10.78103814
75MAP2K40.77985189
76MAP2K20.77901239
77CAMK10.77753154
78MAPKAPK30.76354476
79PTK2B0.72600475
80TTN0.72556310
81RET0.72381149
82ITK0.71550231
83MAPK100.69254810
84NLK0.68651647
85RPS6KA60.68441023
86SGK30.68397954
87CDK150.68265914
88RPS6KA30.66158451
89EPHA30.65581228
90MTOR0.65364449
91SGK10.65056234
92LATS20.64351182
93CDK180.63785129
94CAMK1D0.63664738
95PRKCG0.63601266
96PASK0.62990798
97PDPK10.62704953
98CDK11A0.62364317
99SGK4940.62178552
100SGK2230.62178552
101PHKG10.61216250
102PHKG20.61216250
103ERBB20.60180093
104RIPK40.58765074
105LRRK20.57612080
106DYRK1B0.57533304
107BRD40.57317574
108CDK140.52976131
109JAK30.52423581
110MAP3K130.52127058
111PDGFRB0.52047298
112GSK3B0.51631655
113TNK20.49869591
114MAP3K60.48614978
115MAPK150.48316145
116NEK60.47974935
117BRSK10.47898117
118MATK0.47603632
119CSNK1E0.47258568
120PRKCZ0.46172236
121PDK10.46109568
122HCK0.45851945
123CDK40.44771187
124PRKAA10.44033531
125LMTK20.43608038
126PRKAA20.43509190
127MAPK140.43489140
128LATS10.43375699
129SGK20.42871799
130* CDK20.42592055
131MAP3K10.41853810
132PTK20.41274828
133FYN0.40750851
134MAPK80.40559325
135IKBKE0.40308473
136BLK0.40016269
137MAPK70.39866541
138CDK30.39269688
139PRKDC0.38090186
140PTK60.38075782
141CSNK1D0.37929973
142RPS6KA20.37585823
143DYRK1A0.37253298
144CDK60.37067318
145MAP3K110.36973274
146CDC70.35361203
147MST40.34760755
148MAPK110.33296459
149CDK190.33168488

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.11046018
2Olfactory transduction_Homo sapiens_hsa047402.94006459
3Synaptic vesicle cycle_Homo sapiens_hsa047212.72099223
4GABAergic synapse_Homo sapiens_hsa047272.43076255
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.31683023
6Circadian entrainment_Homo sapiens_hsa047132.29509434
7Nicotine addiction_Homo sapiens_hsa050332.18552503
8Morphine addiction_Homo sapiens_hsa050322.16536698
9Histidine metabolism_Homo sapiens_hsa003402.13119175
10Glutamatergic synapse_Homo sapiens_hsa047242.10245769
11Long-term potentiation_Homo sapiens_hsa047202.03740880
12Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.97125215
13Insulin secretion_Homo sapiens_hsa049111.94791651
14Phenylalanine metabolism_Homo sapiens_hsa003601.93698019
15Amphetamine addiction_Homo sapiens_hsa050311.91260039
16Dopaminergic synapse_Homo sapiens_hsa047281.88934258
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.88486445
18Cholinergic synapse_Homo sapiens_hsa047251.78802257
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73452016
20Cocaine addiction_Homo sapiens_hsa050301.68841897
21Salivary secretion_Homo sapiens_hsa049701.63463929
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59549501
23Gastric acid secretion_Homo sapiens_hsa049711.57354171
24mTOR signaling pathway_Homo sapiens_hsa041501.48509915
25Oxytocin signaling pathway_Homo sapiens_hsa049211.46802992
26Other glycan degradation_Homo sapiens_hsa005111.45222455
27Type II diabetes mellitus_Homo sapiens_hsa049301.40337968
28Renin secretion_Homo sapiens_hsa049241.37347516
29Acute myeloid leukemia_Homo sapiens_hsa052211.37324520
30Chemical carcinogenesis_Homo sapiens_hsa052041.36595164
31GnRH signaling pathway_Homo sapiens_hsa049121.34477901
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33794521
33Nitrogen metabolism_Homo sapiens_hsa009101.31772946
34Tyrosine metabolism_Homo sapiens_hsa003501.31673258
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31504420
36ABC transporters_Homo sapiens_hsa020101.30420959
37Gap junction_Homo sapiens_hsa045401.28059178
38Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.26841146
39Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23911046
40Glioma_Homo sapiens_hsa052141.22441104
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.21265487
42Thyroid hormone signaling pathway_Homo sapiens_hsa049191.20365551
43cAMP signaling pathway_Homo sapiens_hsa040241.20316640
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.19744371
45Calcium signaling pathway_Homo sapiens_hsa040201.19231867
46Taste transduction_Homo sapiens_hsa047421.16983863
47Estrogen signaling pathway_Homo sapiens_hsa049151.15916672
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.15035130
49Leukocyte transendothelial migration_Homo sapiens_hsa046701.11544799
50Serotonergic synapse_Homo sapiens_hsa047261.10572372
51Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09705350
52Long-term depression_Homo sapiens_hsa047301.09656410
53Glycerophospholipid metabolism_Homo sapiens_hsa005641.09418183
54T cell receptor signaling pathway_Homo sapiens_hsa046601.08280792
55cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04157600
56Oocyte meiosis_Homo sapiens_hsa041141.02564842
57Melanogenesis_Homo sapiens_hsa049161.01840604
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.98394386
59B cell receptor signaling pathway_Homo sapiens_hsa046620.96977376
60Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93972315
61Dorso-ventral axis formation_Homo sapiens_hsa043200.93231875
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91869485
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.91374463
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.91014895
65ErbB signaling pathway_Homo sapiens_hsa040120.90948512
66Hepatitis C_Homo sapiens_hsa051600.90069277
67Non-small cell lung cancer_Homo sapiens_hsa052230.89496180
68Adherens junction_Homo sapiens_hsa045200.88860249
69beta-Alanine metabolism_Homo sapiens_hsa004100.86851776
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84607133
71Dilated cardiomyopathy_Homo sapiens_hsa054140.84418770
72Alcoholism_Homo sapiens_hsa050340.84055875
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.83652044
74Choline metabolism in cancer_Homo sapiens_hsa052310.82240811
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81926153
76Thyroid hormone synthesis_Homo sapiens_hsa049180.79890605
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.79651197
78Circadian rhythm_Homo sapiens_hsa047100.79362142
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.77652894
80Linoleic acid metabolism_Homo sapiens_hsa005910.77238595
81VEGF signaling pathway_Homo sapiens_hsa043700.76916915
82Prostate cancer_Homo sapiens_hsa052150.76100663
83Endometrial cancer_Homo sapiens_hsa052130.75991918
84Inositol phosphate metabolism_Homo sapiens_hsa005620.75138368
85Insulin resistance_Homo sapiens_hsa049310.74726760
86Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74209218
87MAPK signaling pathway_Homo sapiens_hsa040100.74055279
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72581156
89Osteoclast differentiation_Homo sapiens_hsa043800.72526858
90Pancreatic cancer_Homo sapiens_hsa052120.72231115
91Axon guidance_Homo sapiens_hsa043600.71812005
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71650918
93Notch signaling pathway_Homo sapiens_hsa043300.71591100
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71037967
95mRNA surveillance pathway_Homo sapiens_hsa030150.70500048
96Glucagon signaling pathway_Homo sapiens_hsa049220.69967233
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.69697341
98Rap1 signaling pathway_Homo sapiens_hsa040150.69195685
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67034753
100Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66911447
101Hedgehog signaling pathway_Homo sapiens_hsa043400.66889110
102Pancreatic secretion_Homo sapiens_hsa049720.66190061
103Wnt signaling pathway_Homo sapiens_hsa043100.66114796
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64601282
105Hippo signaling pathway_Homo sapiens_hsa043900.64597144
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63495145
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60704006
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59106979
109Prolactin signaling pathway_Homo sapiens_hsa049170.59051472
110Chronic myeloid leukemia_Homo sapiens_hsa052200.58961976
111Insulin signaling pathway_Homo sapiens_hsa049100.58730047
112Lysine degradation_Homo sapiens_hsa003100.58220765
113Amoebiasis_Homo sapiens_hsa051460.57657888
114Primary immunodeficiency_Homo sapiens_hsa053400.57041100
115Renal cell carcinoma_Homo sapiens_hsa052110.56694494
116Colorectal cancer_Homo sapiens_hsa052100.56536010
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56470246
118Focal adhesion_Homo sapiens_hsa045100.54435296
119Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.53770790
120Sphingolipid metabolism_Homo sapiens_hsa006000.53411618
121Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52663766
122Platelet activation_Homo sapiens_hsa046110.52366127
123ECM-receptor interaction_Homo sapiens_hsa045120.52255129
124Bile secretion_Homo sapiens_hsa049760.51582124
125Jak-STAT signaling pathway_Homo sapiens_hsa046300.50640664
126Fructose and mannose metabolism_Homo sapiens_hsa000510.50386266
127Endocytosis_Homo sapiens_hsa041440.50248544
128Ras signaling pathway_Homo sapiens_hsa040140.48518992
129HTLV-I infection_Homo sapiens_hsa051660.48375862
130Pathways in cancer_Homo sapiens_hsa052000.48288497
131Apoptosis_Homo sapiens_hsa042100.47963341
132Adipocytokine signaling pathway_Homo sapiens_hsa049200.47729011
133Tight junction_Homo sapiens_hsa045300.47435900
134Basal cell carcinoma_Homo sapiens_hsa052170.46938701
135AMPK signaling pathway_Homo sapiens_hsa041520.44752892
136Proteoglycans in cancer_Homo sapiens_hsa052050.44618754
137Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43239249
138Type I diabetes mellitus_Homo sapiens_hsa049400.42937513
139HIF-1 signaling pathway_Homo sapiens_hsa040660.40478971
140Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40212007
141Chemokine signaling pathway_Homo sapiens_hsa040620.39886125
142Bladder cancer_Homo sapiens_hsa052190.38739148
143Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.38330660
144Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37993710
145Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.36731975

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