CRCT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1peptide cross-linking (GO:0018149)8.41666219
2positive regulation of cellular amide metabolic process (GO:0034250)8.39339244
3multicellular organismal water homeostasis (GO:0050891)8.22261404
4keratinocyte differentiation (GO:0030216)7.90273990
5water homeostasis (GO:0030104)6.80128205
6hemidesmosome assembly (GO:0031581)6.69915975
7G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)6.54653385
8intermediate filament organization (GO:0045109)6.44189917
9epidermal cell differentiation (GO:0009913)6.34582193
10regulation of type B pancreatic cell apoptotic process (GO:2000674)6.06237296
11epidermis development (GO:0008544)5.66036721
12keratinocyte proliferation (GO:0043616)5.63565374
13skin morphogenesis (GO:0043589)5.56091480
14bundle of His cell to Purkinje myocyte communication (GO:0086069)5.52957467
15defense response to Gram-negative bacterium (GO:0050829)5.50292893
16defense response to fungus (GO:0050832)5.46845917
17positive regulation of p38MAPK cascade (GO:1900745)5.39829178
18negative regulation of interleukin-17 production (GO:0032700)5.32810765
19positive regulation of humoral immune response (GO:0002922)5.26240154
20antimicrobial humoral response (GO:0019730)5.14655994
21long-chain fatty acid biosynthetic process (GO:0042759)4.82057358
22fatty acid elongation (GO:0030497)4.72763381
23negative regulation of interferon-gamma production (GO:0032689)4.70606258
24positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.60046960
25glucosamine-containing compound catabolic process (GO:1901072)4.28290205
26hair cell differentiation (GO:0035315)4.21860241
27regulation of cellular amide metabolic process (GO:0034248)4.20627491
28regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)4.09721979
29positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)4.09721979
30ectoderm development (GO:0007398)4.08463642
31positive regulation of T-helper 1 type immune response (GO:0002827)4.06249561
32intermediate filament cytoskeleton organization (GO:0045104)4.03133828
33regulation of p38MAPK cascade (GO:1900744)4.01801393
34negative regulation of catenin import into nucleus (GO:0035414)4.01240253
35adhesion of symbiont to host cell (GO:0044650)3.98667537
36virion attachment to host cell (GO:0019062)3.98667537
37intermediate filament-based process (GO:0045103)3.92040218
38positive regulation of interleukin-8 secretion (GO:2000484)3.84525820
39regulation of ruffle assembly (GO:1900027)3.81290726
40G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.79025691
41tooth mineralization (GO:0034505)3.77226636
42detection of bacterium (GO:0016045)3.75691363
43keratinocyte development (GO:0003334)3.74468521
44phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.73423418
45response to fungus (GO:0009620)3.72817454
46regulation of hypersensitivity (GO:0002883)3.69082064
47adhesion of symbiont to host (GO:0044406)3.60253628
48positive regulation of epidermal cell differentiation (GO:0045606)3.58567282
49positive regulation of hair follicle development (GO:0051798)3.48718541
50positive regulation of hair cycle (GO:0042635)3.48718541
51regulation of keratinocyte differentiation (GO:0045616)3.48325699
52purinergic nucleotide receptor signaling pathway (GO:0035590)3.48053884
53hair follicle morphogenesis (GO:0031069)3.44789283
54regulation of glomerulus development (GO:0090192)3.44047791
55linoleic acid metabolic process (GO:0043651)3.40846928
56regulation of transforming growth factor beta1 production (GO:0032908)3.39979352
57negative regulation of keratinocyte proliferation (GO:0010839)3.34631876
58positive regulation of keratinocyte differentiation (GO:0045618)3.33122592
59phosphatidylcholine acyl-chain remodeling (GO:0036151)3.30410646
60antibacterial humoral response (GO:0019731)3.30171124
61cell wall macromolecule catabolic process (GO:0016998)3.28371871
62cell wall macromolecule metabolic process (GO:0044036)3.28371871
63regulation of axon regeneration (GO:0048679)3.25336838
64regulation of neuron projection regeneration (GO:0070570)3.25336838
65positive regulation of transforming growth factor beta production (GO:0071636)3.24460332
66regulation of receptor recycling (GO:0001919)3.20631350
67detection of other organism (GO:0098543)3.15831409
68epithelial cell differentiation (GO:0030855)3.10279734
69positive regulation of response to biotic stimulus (GO:0002833)3.09469798
70positive regulation of monocyte chemotaxis (GO:0090026)3.08597539
71activation of MAPKKK activity (GO:0000185)3.06891270
72dendritic cell migration (GO:0036336)3.01154383
73keratinization (GO:0031424)20.2768091
74surfactant homeostasis (GO:0043129)2.99347842
75negative regulation of cell fate specification (GO:0009996)2.98503236
76ceramide biosynthetic process (GO:0046513)2.98026534
77skin development (GO:0043588)2.95497442
78regulation of cholesterol homeostasis (GO:2000188)2.95341461
79regulation of interleukin-17 production (GO:0032660)2.94425392
80cellular response to arsenic-containing substance (GO:0071243)2.93748007
81lipoxygenase pathway (GO:0019372)2.93339066
82atrioventricular valve morphogenesis (GO:0003181)2.92859978
83regulation of T-helper 1 type immune response (GO:0002825)2.91176061
84phosphatidylinositol acyl-chain remodeling (GO:0036149)2.90031623
85positive regulation of meiotic cell cycle (GO:0051446)2.88987078
86negative regulation of cAMP-mediated signaling (GO:0043951)2.88860177
87sphingosine metabolic process (GO:0006670)2.88701019
88positive regulation of epidermis development (GO:0045684)2.87798713
89establishment of tissue polarity (GO:0007164)2.87221418
90establishment of planar polarity (GO:0001736)2.87221418
91phosphatidylserine acyl-chain remodeling (GO:0036150)2.85840700
92apical protein localization (GO:0045176)2.84326076
93regulation of hair follicle development (GO:0051797)2.84236345
94mitotic nuclear envelope reassembly (GO:0007084)2.84078086
95nuclear envelope reassembly (GO:0031468)2.84078086
96positive thymic T cell selection (GO:0045059)2.82999103
97negative regulation of muscle hypertrophy (GO:0014741)2.80532732
98chemical homeostasis within a tissue (GO:0048875)2.80325224
99thymic T cell selection (GO:0045061)2.79410046
100long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.76264044
101detection of external biotic stimulus (GO:0098581)2.74580695
102molting cycle process (GO:0022404)2.73794137
103hair cycle process (GO:0022405)2.73794137
104nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.73450498
105sequestering of metal ion (GO:0051238)2.73420003
106phospholipid scrambling (GO:0017121)2.71272791
107gap junction assembly (GO:0016264)2.70436201
108natural killer cell activation involved in immune response (GO:0002323)2.70357401
109negative regulation of cardiac muscle hypertrophy (GO:0010614)2.68987915
110sphingoid metabolic process (GO:0046519)2.67300685
111positive regulation of sterol transport (GO:0032373)2.67128697
112phospholipid efflux (GO:0033700)2.65330529
113negative regulation of cell fate commitment (GO:0010454)2.65219157
114epithelium development (GO:0060429)2.64955569
115regulation of MHC class I biosynthetic process (GO:0045343)2.64270206
116wound healing, spreading of epidermal cells (GO:0035313)2.62408440
117regulation of cell proliferation involved in kidney development (GO:1901722)2.62190419
118regulation of hair cycle (GO:0042634)2.62051478
119regulation of interleukin-8 secretion (GO:2000482)2.61062367
120primary alcohol catabolic process (GO:0034310)2.60429858
121lymph vessel development (GO:0001945)2.57855503
122phosphatidylserine metabolic process (GO:0006658)2.57544538
123regulation of epidermis development (GO:0045682)2.57278136
124regulation of epidermal cell differentiation (GO:0045604)2.55197238
125diol metabolic process (GO:0034311)2.54427355
126defense response to Gram-positive bacterium (GO:0050830)2.54304360
127response to UV-B (GO:0010224)2.54302029
128branching involved in labyrinthine layer morphogenesis (GO:0060670)2.53628121
129positive regulation of glomerulus development (GO:0090193)2.53505454
130positive regulation of cholesterol efflux (GO:0010875)2.53063784
131phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.52544686
132cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.52174676
133dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.50617244
134negative regulation of stress fiber assembly (GO:0051497)2.49565383
135negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.49247968
136long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.48579798
137fibrinolysis (GO:0042730)2.48526316
138eyelid development in camera-type eye (GO:0061029)2.46879451
139planar cell polarity pathway involved in neural tube closure (GO:0090179)2.45881186
140regulation of natural killer cell differentiation (GO:0032823)2.44307501
141purinergic receptor signaling pathway (GO:0035587)2.43743957
142wound healing, spreading of cells (GO:0044319)2.42226587
143cell-substrate junction assembly (GO:0007044)2.37441856
144fatty-acyl-CoA biosynthetic process (GO:0046949)2.35715971
145positive regulation of cholesterol transport (GO:0032376)2.34472343
146establishment of skin barrier (GO:0061436)14.3301821
147hair cycle (GO:0042633)13.7946213
148molting cycle (GO:0042303)13.7946213
149regulation of water loss via skin (GO:0033561)12.4905416
150desmosome organization (GO:0002934)12.0673491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.95956735
2P63_26484246_Chip-Seq_KERATINOCYTES_Human3.41136611
3SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.56894914
4ESR1_21235772_ChIP-Seq_MCF-7_Human2.48777434
5ESR2_21235772_ChIP-Seq_MCF-7_Human2.36823190
6SOX9_24532713_ChIP-Seq_HFSC_Mouse2.23882156
7ESR1_20079471_ChIP-ChIP_T-47D_Human2.17787220
8PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.17126405
9VDR_22108803_ChIP-Seq_LS180_Human2.14876478
10TP63_17297297_ChIP-ChIP_HaCaT_Human13.1648716
11TRIM28_21343339_ChIP-Seq_HEK293_Human1.98399716
12FOXO3_23340844_ChIP-Seq_DLD1_Human1.91537422
13SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.91279211
14SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.91279211
15ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.83923389
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.79306692
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.69973423
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.64620373
19ZNF217_24962896_ChIP-Seq_MCF-7_Human1.61167910
20TP63_23658742_ChIP-Seq_EP156T_Human1.48872088
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44015856
22HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42696484
23ERG_20517297_ChIP-Seq_VCAP_Human1.42066022
24RXR_22108803_ChIP-Seq_LS180_Human1.41922675
25ATF3_27146783_Chip-Seq_COLON_Human1.40740219
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.40247930
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37783717
28ZNF263_19887448_ChIP-Seq_K562_Human1.37713415
29CTCF_20526341_ChIP-Seq_ESCs_Human1.37672807
30* GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.37448816
31KLF5_25053715_ChIP-Seq_YYC3_Human1.37425711
32SOX2_20726797_ChIP-Seq_SW620_Human1.36008000
33* CTCF_27219007_Chip-Seq_Bcells_Human1.34519919
34ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.32020156
35RACK7_27058665_Chip-Seq_MCF-7_Human1.29740562
36RUNX1_27514584_Chip-Seq_MCF-7_Human1.28842242
37FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.27832040
38GATA3_24758297_ChIP-Seq_MCF-7_Human1.26869202
39BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.26056564
40TP53_18474530_ChIP-ChIP_U2OS_Human1.23743943
41TP53_20018659_ChIP-ChIP_R1E_Mouse1.23356776
42* GATA6_21074721_ChIP-Seq_CACO-2_Human1.22368916
43KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.21969424
44ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21882114
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.21067055
46* TP63_22573176_ChIP-Seq_HFKS_Human1.20701762
47CJUN_26792858_Chip-Seq_BT549_Human1.20118282
48DNAJC2_21179169_ChIP-ChIP_NT2_Human1.18072823
49SOX2_27498859_Chip-Seq_STOMACH_Mouse1.16986845
50AHR_22903824_ChIP-Seq_MCF-7_Human1.16964319
51BCAT_22108803_ChIP-Seq_LS180_Human1.16682900
52ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.15936233
53CEBPB_22108803_ChIP-Seq_LS180_Human1.12763775
54SMC4_20622854_ChIP-Seq_HELA_Human1.11700259
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09780541
56NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.07942221
57E2F1_20622854_ChIP-Seq_HELA_Human1.07790903
58* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.06930279
59EGR1_19032775_ChIP-ChIP_M12_Human1.06860665
60PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06178635
61SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05396421
62UBF1/2_26484160_Chip-Seq_HMECs_Human1.04127628
63LXR_22292898_ChIP-Seq_THP-1_Human1.02846668
64BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01773731
65* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.01301168
66P53_21459846_ChIP-Seq_SAOS-2_Human1.00618054
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99499172
68VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.99343779
69* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98348009
70* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96046266
71GATA4_25053715_ChIP-Seq_YYC3_Human0.96021386
72AR_21572438_ChIP-Seq_LNCaP_Human0.95777452
73JARID2_20075857_ChIP-Seq_MESCs_Mouse0.95595283
74ELK3_25401928_ChIP-Seq_HUVEC_Human0.95274205
75CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94871054
76SMAD_19615063_ChIP-ChIP_OVARY_Human0.94526524
77MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.93761900
78BCOR_27268052_Chip-Seq_Bcells_Human0.93186121
79PPARA_22158963_ChIP-Seq_LIVER_Mouse0.92924644
80CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.92377056
81KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.91846015
82TAF2_19829295_ChIP-Seq_ESCs_Human0.91691448
83STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.91592310
84STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.90268130
85CLOCK_20551151_ChIP-Seq_293T_Human0.89369370
86ARNT_22903824_ChIP-Seq_MCF-7_Human0.88601129
87P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.88190228
88SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.87329652
89EZH2_27304074_Chip-Seq_ESCs_Mouse0.87253681
90AUTS2_25519132_ChIP-Seq_293T-REX_Human0.87232709
91RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.86757383
92RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.86539518
93* GATA3_21867929_ChIP-Seq_TH1_Mouse0.85062544
94TCF4_18268006_ChIP-ChIP_LS174T_Human0.84724072
95FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84266426
96CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83977167
97RNF2_27304074_Chip-Seq_ESCs_Mouse0.83450822
98SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.83181300
99TP53_16413492_ChIP-PET_HCT116_Human0.82899671
100JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82897649
101* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.82841089
102ERG_21242973_ChIP-ChIP_JURKAT_Human0.81796353
103SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.80778821
104SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.80730687
105STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.80478984
106YY1_22570637_ChIP-Seq_MALME-3M_Human0.79532743
107GATA6_25053715_ChIP-Seq_YYC3_Human0.79355036
108HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.78873929
109CSB_26484114_Chip-Seq_FIBROBLAST_Human0.78729092
110TCF4_22108803_ChIP-Seq_LS180_Human0.78469143
111OCT1_27270436_Chip-Seq_PROSTATE_Human0.78310410
112RNF2_18974828_ChIP-Seq_MESCs_Mouse0.78050820
113EZH2_18974828_ChIP-Seq_MESCs_Mouse0.78050820
114THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.77925248
115SA1_27219007_Chip-Seq_Bcells_Human0.77611243
116SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.77604227
117EED_16625203_ChIP-ChIP_MESCs_Mouse0.77310920
118FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.77171409
119SA1_27219007_Chip-Seq_ERYTHROID_Human0.75770058
120FOXH1_21741376_ChIP-Seq_ESCs_Human0.75523052
121* EZH2_27294783_Chip-Seq_ESCs_Mouse0.75184569
122BCL6_27268052_Chip-Seq_Bcells_Human0.75083184
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.74271275
124WT1_19549856_ChIP-ChIP_CCG9911_Human0.73230587
125NANOG_20526341_ChIP-Seq_ESCs_Human0.73095183
126ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.73078800
127FOXM1_26456572_ChIP-Seq_MCF-7_Human0.73027590
128* RBPJ_21746931_ChIP-Seq_IB4_Human0.71826032
129GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.69573638
130SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.69466999
131TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.67005937
132RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.66445806
133FOXA1_25552417_ChIP-Seq_VCAP_Human0.65921815
134NRF2_20460467_ChIP-Seq_MEFs_Mouse0.65718792
135NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.65718792
136EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.62034835

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.29885309
2MP0005275_abnormal_skin_tensile6.61118331
3MP0005501_abnormal_skin_physiology4.98221559
4MP0010234_abnormal_vibrissa_follicle4.46254287
5MP0000579_abnormal_nail_morphology4.42204713
6MP0003941_abnormal_skin_development3.94022416
7MP0002098_abnormal_vibrissa_morphology3.89566855
8MP0000647_abnormal_sebaceous_gland3.58846075
9MP0004381_abnormal_hair_follicle3.54170557
10MP0002060_abnormal_skin_morphology3.41491638
11MP0001216_abnormal_epidermal_layer3.31257748
12MP0004947_skin_inflammation3.29720526
13MP0005451_abnormal_body_composition3.21023364
14MP0002254_reproductive_system_inflammat3.20436705
15MP0010771_integument_phenotype3.04724474
16MP0003705_abnormal_hypodermis_morpholog2.71198230
17MP0000383_abnormal_hair_follicle2.64005004
18MP0010678_abnormal_skin_adnexa2.59668321
19MP0000377_abnormal_hair_follicle2.41306709
20MP0003453_abnormal_keratinocyte_physiol2.37621327
21MP0000427_abnormal_hair_cycle2.28861630
22MP0000467_abnormal_esophagus_morphology2.05356759
23MP0004043_abnormal_pH_regulation2.01333080
24MP0001243_abnormal_dermal_layer1.99955186
25MP0002009_preneoplasia1.93999854
26MP0009931_abnormal_skin_appearance1.82822770
27MP0000762_abnormal_tongue_morphology1.70569893
28MP0000367_abnormal_coat/_hair1.69439378
29MP0001346_abnormal_lacrimal_gland1.64361259
30MP0001851_eye_inflammation1.58422690
31MP0001191_abnormal_skin_condition1.57221993
32MP0004185_abnormal_adipocyte_glucose1.43647346
33MP0005377_hearing/vestibular/ear_phenot1.41792797
34MP0003878_abnormal_ear_physiology1.41792797
35MP0003566_abnormal_cell_adhesion1.33859214
36MP0003191_abnormal_cellular_cholesterol1.30951708
37MP0003136_yellow_coat_color1.24099058
38MP0001188_hyperpigmentation1.22433527
39MP0002234_abnormal_pharynx_morphology1.20107669
40MP0002877_abnormal_melanocyte_morpholog1.06717984
41MP0003011_delayed_dark_adaptation1.04894269
42MP0002163_abnormal_gland_morphology1.03421005
43MP0002006_tumorigenesis0.99460982
44MP0001340_abnormal_eyelid_morphology0.94846727
45MP0000750_abnormal_muscle_regeneration0.91105047
46MP0003315_abnormal_perineum_morphology0.80874149
47MP0002166_altered_tumor_susceptibility0.80046408
48MP0000566_synostosis0.78394140
49MP0002095_abnormal_skin_pigmentation0.78209309
50MP0003300_gastrointestinal_ulcer0.77137116
51MP0003763_abnormal_thymus_physiology0.76313424
52MP0004782_abnormal_surfactant_physiolog0.70805820
53MP0005409_darkened_coat_color0.70349087
54MP0005023_abnormal_wound_healing0.65576727
55MP0009053_abnormal_anal_canal0.64806411
56MP0001784_abnormal_fluid_regulation0.62059030
57MP0003950_abnormal_plasma_membrane0.60064475
58MP0000465_gastrointestinal_hemorrhage0.59193519
59MP0000627_abnormal_mammary_gland0.58227646
60MP0002177_abnormal_outer_ear0.57583045
61MP0000372_irregular_coat_pigmentation0.55460516
62MP0003755_abnormal_palate_morphology0.54900325
63MP0008004_abnormal_stomach_pH0.53781636
64MP0000537_abnormal_urethra_morphology0.51734692
65MP0009379_abnormal_foot_pigmentation0.51270748
66MP0005379_endocrine/exocrine_gland_phen0.50406601
67MP0009384_cardiac_valve_regurgitation0.49953177
68MP0005187_abnormal_penis_morphology0.48526595
69MP0009333_abnormal_splenocyte_physiolog0.48053605
70MP0008438_abnormal_cutaneous_collagen0.47432904
71MP0010030_abnormal_orbit_morphology0.40393752
72MP0009672_abnormal_birth_weight0.40351826
73MP0001348_abnormal_lacrimal_gland0.40306161
74MP0000470_abnormal_stomach_morphology0.39869167
75MP0005666_abnormal_adipose_tissue0.39386616
76MP0005503_abnormal_tendon_morphology0.38727584
77MP0003221_abnormal_cardiomyocyte_apopto0.38673989
78MP0004264_abnormal_extraembryonic_tissu0.37692666
79MP0004019_abnormal_vitamin_homeostasis0.37593130
80MP0001849_ear_inflammation0.37002055
81MP0002249_abnormal_larynx_morphology0.36551762
82MP0002090_abnormal_vision0.36365007
83MP0005076_abnormal_cell_differentiation0.35622389
84MP0003656_abnormal_erythrocyte_physiolo0.35056831
85MP0000613_abnormal_salivary_gland0.34944101
86MP0005508_abnormal_skeleton_morphology0.34777883
87MP0005075_abnormal_melanosome_morpholog0.34346899
88MP0001502_abnormal_circadian_rhythm0.34164338
89MP0003448_altered_tumor_morphology0.33657287
90MP0004883_abnormal_blood_vessel0.33167461
91MP0008961_abnormal_basal_metabolism0.32720861
92MP0003828_pulmonary_edema0.31917552
93MP0002282_abnormal_trachea_morphology0.31664172
94MP0000432_abnormal_head_morphology0.30445347
95MP0000003_abnormal_adipose_tissue0.30297424
96MP0010352_gastrointestinal_tract_polyps0.29314946
97MP0002136_abnormal_kidney_physiology0.29044797
98MP0003329_amyloid_beta_deposits0.27181253
99MP0001873_stomach_inflammation0.25512210
100MP0001765_abnormal_ion_homeostasis0.25464223
101MP0009840_abnormal_foam_cell0.24165647
102MP0001666_abnormal_nutrient_absorption0.23752063
103MP0002111_abnormal_tail_morphology0.23135501
104MP0005375_adipose_tissue_phenotype0.22721379
105MP0002971_abnormal_brown_adipose0.22660114
106MP0002148_abnormal_hypersensitivity_rea0.22418512
107MP0003091_abnormal_cell_migration0.21175714
108MP0004272_abnormal_basement_membrane0.20749017
109MP0009780_abnormal_chondrocyte_physiolo0.19996271
110MP0004510_myositis0.19942103
111MP0001177_atelectasis0.19933570
112MP0000371_diluted_coat_color0.19721202
113MP0003385_abnormal_body_wall0.19424748
114MP0004484_altered_response_of0.19307484
115MP0005388_respiratory_system_phenotype0.18806513
116MP0002133_abnormal_respiratory_system0.18806513
117MP0003638_abnormal_response/metabolism_0.18798328
118MP0004197_abnormal_fetal_growth/weight/0.18361960
119MP0002896_abnormal_bone_mineralization0.18347678
120MP0000678_abnormal_parathyroid_gland0.17520172
121MP0000751_myopathy0.16928480
122MP0000759_abnormal_skeletal_muscle0.16866428
123MP0002972_abnormal_cardiac_muscle0.16447642
124MP0004885_abnormal_endolymph0.16428988
125MP0001756_abnormal_urination0.16367224
126MP0005193_abnormal_anterior_eye0.14928061
127MP0008995_early_reproductive_senescence0.13816437
128MP0001186_pigmentation_phenotype0.13766706
129MP0009115_abnormal_fat_cell0.11146574
130MP0002138_abnormal_hepatobiliary_system0.10504024
131MP0005636_abnormal_mineral_homeostasis0.09135897
132MP0000015_abnormal_ear_pigmentation0.09044607
133MP0009765_abnormal_xenobiotic_induced0.08846456
134MP0002075_abnormal_coat/hair_pigmentati0.08610325
135MP0002295_abnormal_pulmonary_circulatio0.08450118
136MP0008260_abnormal_autophagy0.06395507
137MP0002697_abnormal_eye_size0.06131090
138MP0002970_abnormal_white_adipose0.04243161
139MP0002081_perinatal_lethality0.03118546

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)9.17514670
2Increased IgE level (HP:0003212)7.67811851
3Woolly hair (HP:0002224)6.77921694
4Abnormality of nail color (HP:0100643)6.72113469
5Palmoplantar hyperkeratosis (HP:0000972)6.05647856
6Plantar hyperkeratosis (HP:0007556)5.92514724
7Right ventricular cardiomyopathy (HP:0011663)5.85459598
8Palmar hyperkeratosis (HP:0010765)5.68759970
9Congenital ichthyosiform erythroderma (HP:0007431)5.64950093
10Onycholysis (HP:0001806)5.51127600
11Erythema (HP:0010783)5.37652233
12Fragile nails (HP:0001808)5.20785267
13Pustule (HP:0200039)4.91285982
14Erythroderma (HP:0001019)4.86917957
15Autoimmune hemolytic anemia (HP:0001890)4.86004683
16Pili torti (HP:0003777)4.72608833
17Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.60014397
18Conjunctival hamartoma (HP:0100780)4.59561143
19Gangrene (HP:0100758)4.51517835
20Thick nail (HP:0001805)4.32698828
21Nail dystrophy (HP:0008404)4.26528461
22Brittle hair (HP:0002299)4.12310454
23Milia (HP:0001056)4.07596962
24Areflexia of lower limbs (HP:0002522)3.83206411
25Hyporeflexia of lower limbs (HP:0002600)3.75472579
26Abnormal blistering of the skin (HP:0008066)3.71106858
27Oral leukoplakia (HP:0002745)3.68025362
28Parakeratosis (HP:0001036)3.59440647
29Abnormal hair laboratory examination (HP:0003328)3.49712050
30Curly hair (HP:0002212)3.45831147
31Concave nail (HP:0001598)3.44120790
32Hypohidrosis (HP:0000966)3.41966412
33Corneal erosion (HP:0200020)3.41794953
34Alopecia of scalp (HP:0002293)3.26939380
35Abnormality of small intestinal villus morphology (HP:0011472)3.24581370
36Villous atrophy (HP:0011473)3.24581370
37Distal lower limb muscle weakness (HP:0009053)3.16680891
38Ectropion (HP:0000656)3.15636566
39Palmoplantar keratoderma (HP:0000982)3.12708477
40Ventricular tachycardia (HP:0004756)3.12680203
41Sparse eyelashes (HP:0000653)3.11402860
42Stomatitis (HP:0010280)2.95383893
43Achilles tendon contracture (HP:0001771)2.90078860
44Pruritus (HP:0000989)2.87065615
45Abnormality of the salivary glands (HP:0010286)2.84250239
46Lip pit (HP:0100267)2.83847198
47Laryngomalacia (HP:0001601)2.78810487
48Round ear (HP:0100830)2.78228088
49Eczematoid dermatitis (HP:0000976)2.76996939
50Abnormality of hair growth rate (HP:0011363)2.73540344
51Slow-growing hair (HP:0002217)2.73540344
52Furrowed tongue (HP:0000221)2.72589870
53Abnormality of the Achilles tendon (HP:0005109)2.68180839
54Absent eyelashes (HP:0000561)2.67353227
55Ridged nail (HP:0001807)2.66995232
56Hamartoma of the eye (HP:0010568)2.66025197
57Oligodontia (HP:0000677)2.60388860
58Atrophic scars (HP:0001075)2.58708590
59Hypergammaglobulinemia (HP:0010702)2.55665014
60Follicular hyperkeratosis (HP:0007502)2.39415919
61Abnormal pupillary function (HP:0007686)2.34643816
62Acanthosis nigricans (HP:0000956)2.32912281
63Absent hair (HP:0002298)2.31281052
64Advanced eruption of teeth (HP:0006288)2.30744124
65Lack of skin elasticity (HP:0100679)2.30329708
66Urticaria (HP:0001025)2.29394650
67Increased connective tissue (HP:0009025)2.21717489
68Distal arthrogryposis (HP:0005684)2.19370898
69Aplasia cutis congenita (HP:0001057)2.17987621
70Natal tooth (HP:0000695)2.17236326
71Type 1 muscle fiber predominance (HP:0003803)2.16290442
72Sparse scalp hair (HP:0002209)2.14253540
73Malignant hyperthermia (HP:0002047)2.09968898
74Verrucae (HP:0200043)2.09440681
75Papilloma (HP:0012740)2.09440681
76Abnormality of the axillary hair (HP:0100134)2.08761000
77Abnormality of secondary sexual hair (HP:0009888)2.08761000
78Alveolar cell carcinoma (HP:0006519)2.03870437
79Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.99036940
80Muscle fiber inclusion bodies (HP:0100299)1.98339850
81Anonychia (HP:0001798)1.97304377
82Amelogenesis imperfecta (HP:0000705)1.95144674
83Neck muscle weakness (HP:0000467)1.87813566
84Nemaline bodies (HP:0003798)1.85952426
85Fragile skin (HP:0001030)1.84492719
86Dehydration (HP:0001944)1.82011940
87Neoplasm of the tracheobronchial system (HP:0100552)1.80102049
88Sepsis (HP:0100806)1.79514073
89Muscle fiber splitting (HP:0003555)1.78924528
90Hyperhidrosis (HP:0000975)1.77265694
91Dry hair (HP:0011359)1.75818953
92Amniotic constriction ring (HP:0009775)1.75640155
93Abnormality of placental membranes (HP:0011409)1.75640155
94Popliteal pterygium (HP:0009756)1.74859003
95Abnormality of the parietal bone (HP:0002696)1.73998117
96Autoamputation (HP:0001218)1.73971444
97Distal lower limb amyotrophy (HP:0008944)1.72257927
98Fatigable weakness (HP:0003473)1.71282140
99Abnormality of the neuromuscular junction (HP:0003398)1.71282140
100Conical tooth (HP:0000698)1.71025857
101Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69490118
102Dry skin (HP:0000958)1.69396807
103Sudden death (HP:0001699)1.68800312
104Abnormality of the gastric mucosa (HP:0004295)1.67436531
105Congenital, generalized hypertrichosis (HP:0004540)1.66114492
106Blepharitis (HP:0000498)1.65125065
107Carious teeth (HP:0000670)1.61876603
108Hyperactive renin-angiotensin system (HP:0000841)1.60536458
109Supernumerary ribs (HP:0005815)1.57647252
110Multifactorial inheritance (HP:0001426)1.57503082
111Anhidrosis (HP:0000970)1.57474511
112Hypoplastic labia majora (HP:0000059)1.57304092
113Abnormality of permanent molar morphology (HP:0011071)1.55615964
114Abnormality of the dental root (HP:0006486)1.55615964
115Taurodontia (HP:0000679)1.55615964
116Sensory axonal neuropathy (HP:0003390)1.55519228
117Calcaneovalgus deformity (HP:0001848)1.55265092
118Elbow flexion contracture (HP:0002987)1.54849471
119Exercise-induced myalgia (HP:0003738)1.54331835
120Fine hair (HP:0002213)1.53991674
121Corneal dystrophy (HP:0001131)1.53723387
122Abnormality of the dental pulp (HP:0006479)1.53355838
123Skin ulcer (HP:0200042)1.52856473
124Axonal loss (HP:0003447)1.52453389
125Abnormality of the fingernails (HP:0001231)1.49097174
126Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.47856859
127Emphysema (HP:0002097)1.43921880
128Abnormality of the labia majora (HP:0012881)1.42499576
129Hyperkalemia (HP:0002153)1.40043498
130Malnutrition (HP:0004395)1.37107182
131Asthma (HP:0002099)1.36739169
132Melanocytic nevus (HP:0000995)1.32938385
133Segmental peripheral demyelination/remyelination (HP:0003481)1.27654014
134Paralysis (HP:0003470)1.26548559
135Everted lower lip vermilion (HP:0000232)1.18021964
136Seborrheic dermatitis (HP:0001051)1.14911529
137Recurrent corneal erosions (HP:0000495)1.14000851
138Skin pits (HP:0100276)1.13175253
139Decreased circulating renin level (HP:0003351)1.06793001
140Hoarse voice (HP:0001609)1.06524086

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK34.96557679
2RIPK14.19425334
3MAP3K94.08532590
4FER3.98753143
5BRD43.50999254
6BCR3.37033629
7MST1R3.16735806
8MAP3K33.11817671
9MST43.00965494
10TTN2.73122557
11EPHB22.35398563
12MAP3K112.21343510
13PIK3CG2.20529709
14EPHA22.19684137
15TAOK12.18520924
16DYRK1B2.11201226
17SGK2232.08429684
18SGK4942.08429684
19RPS6KB22.03554224
20EEF2K1.94339665
21FGFR11.89106699
22MAP3K61.89019180
23MAP2K31.81072117
24ABL21.80644263
25DAPK21.71229976
26IRAK11.67699449
27WNK11.65528702
28IRAK21.62512822
29CDK61.56424248
30IRAK41.54627883
31MAP3K21.51827673
32ERN11.47191942
33MAP3K121.44537891
34TAOK21.41716104
35TRPM71.39549958
36MAPKAPK51.37724240
37STK38L1.32934900
38DYRK31.31689978
39LRRK21.30856070
40TGFBR11.30744403
41LATS11.27384725
42CDK41.25863843
43MAP3K11.21027029
44OBSCN1.16470811
45MAP2K61.16209375
46TGFBR21.13361693
47MAPK151.07905991
48AKT31.05297192
49NTRK21.04025230
50SGK21.02468670
51SGK30.99302470
52MAP3K70.98499694
53MARK20.97149147
54PDGFRB0.96528047
55TBK10.94417263
56ADRBK10.93652151
57MOS0.93131677
58GSK3A0.91604518
59STK30.90615281
60MET0.82138727
61BMX0.81743694
62CDK90.81285371
63ITK0.81255229
64MAPKAPK20.81037523
65EPHA30.80553869
66PAK30.80146260
67PTK60.79067872
68PKN10.76609564
69ERBB40.72997697
70GRK70.72883841
71DDR20.72638451
72STK110.72248884
73EPHB10.68474562
74MAP3K140.67981491
75FGFR40.66684540
76LATS20.65910074
77FGFR20.64884878
78MTOR0.64235772
79HCK0.63388430
80CAMK2G0.63032597
81CAMK2D0.61122633
82PRKCI0.60637159
83AURKA0.60449962
84DMPK0.60120644
85STK100.59824810
86PTK20.57692322
87IRAK30.57037135
88DYRK20.54103230
89TRIB30.53650458
90PRPF4B0.53241355
91GRK60.51344849
92IKBKE0.50411233
93STK380.47797598
94MAP3K50.46979179
95FYN0.46545930
96RPS6KB10.46437075
97MAPK70.45917195
98GRK10.44548141
99GRK50.44386551
100CHUK0.43827743
101SGK10.42517053
102ERBB30.41742296
103PRKD20.41599043
104PIM20.40790843
105BLK0.40375123
106MAP4K10.38756026
107MAP2K10.38665004
108FGFR30.38586364
109NME10.36445376
110BRAF0.35959202
111AURKB0.35442252
112CAMK1D0.33680699
113PHKG20.33448915
114PHKG10.33448915
115KSR20.32939259
116PRKD10.32185757
117IKBKB0.31715385
118PAK20.30438178
119CSK0.30042385
120TNK20.29565171
121CDK120.28880157
122BMPR20.27711376
123TYRO30.27321014
124ABL10.26735102
125FGR0.25930765
126MAPK40.25246179
127TAOK30.25111916
128MAP2K20.24664283
129ROCK10.24456753
130HIPK20.24132322
131MAPK120.23359445
132TYK20.22947958
133SRC0.22595788
134RIPK40.22365007
135PRKACA0.22345288
136PRKAA20.21837487
137NEK60.21294182
138DAPK30.21069036
139PRKCA0.20945129
140CSNK1A10.20440773
141PRKCB0.19961947
142STK240.19903384
143PIM10.19666389
144TIE10.19423366
145RPS6KC10.19235638
146RPS6KL10.19235638
147ROCK20.18965301
148RPS6KA10.17814041

Predicted pathways (KEGG)

RankGene SetZ-score
1Linoleic acid metabolism_Homo sapiens_hsa005913.01616697
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.95922234
3Cyanoamino acid metabolism_Homo sapiens_hsa004602.94476287
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.91386943
5Fatty acid elongation_Homo sapiens_hsa000622.83435400
6Bladder cancer_Homo sapiens_hsa052192.65802669
7Circadian rhythm_Homo sapiens_hsa047102.44987601
8Sulfur metabolism_Homo sapiens_hsa009202.32856032
9Arachidonic acid metabolism_Homo sapiens_hsa005902.03354341
10Phenylalanine metabolism_Homo sapiens_hsa003601.99987215
11Fat digestion and absorption_Homo sapiens_hsa049751.93052340
12Ether lipid metabolism_Homo sapiens_hsa005651.87665731
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.85732114
14Histidine metabolism_Homo sapiens_hsa003401.80959474
15Sphingolipid metabolism_Homo sapiens_hsa006001.62426586
16Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.55295037
17Ovarian steroidogenesis_Homo sapiens_hsa049131.55138610
18Retinol metabolism_Homo sapiens_hsa008301.49706915
19Non-small cell lung cancer_Homo sapiens_hsa052231.43731173
20Tight junction_Homo sapiens_hsa045301.36271107
21Basal cell carcinoma_Homo sapiens_hsa052171.33684243
22Staphylococcus aureus infection_Homo sapiens_hsa051501.33315799
23Renin secretion_Homo sapiens_hsa049241.32404369
24Adherens junction_Homo sapiens_hsa045201.31295621
25RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.24708670
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.23948139
27Vascular smooth muscle contraction_Homo sapiens_hsa042701.19964410
28VEGF signaling pathway_Homo sapiens_hsa043701.17152696
29GnRH signaling pathway_Homo sapiens_hsa049121.14842838
30Axon guidance_Homo sapiens_hsa043601.14581062
31Primary immunodeficiency_Homo sapiens_hsa053401.14043702
32ECM-receptor interaction_Homo sapiens_hsa045121.13865941
33Proteoglycans in cancer_Homo sapiens_hsa052051.11986136
34Hippo signaling pathway_Homo sapiens_hsa043901.10753023
35Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10004798
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09727962
37Endocytosis_Homo sapiens_hsa041441.05812948
38Dorso-ventral axis formation_Homo sapiens_hsa043201.04693087
39Leukocyte transendothelial migration_Homo sapiens_hsa046701.04232614
40Olfactory transduction_Homo sapiens_hsa047400.96589682
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.95448566
42Ras signaling pathway_Homo sapiens_hsa040140.95019556
43Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.94670711
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.94225258
45T cell receptor signaling pathway_Homo sapiens_hsa046600.92936228
46Steroid biosynthesis_Homo sapiens_hsa001000.92432034
47Choline metabolism in cancer_Homo sapiens_hsa052310.92295117
48Acute myeloid leukemia_Homo sapiens_hsa052210.92074591
49Platelet activation_Homo sapiens_hsa046110.91498286
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91114477
51Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.91057640
52Tyrosine metabolism_Homo sapiens_hsa003500.90157863
53Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.89551570
54ABC transporters_Homo sapiens_hsa020100.88971044
55Hematopoietic cell lineage_Homo sapiens_hsa046400.88453213
56Melanogenesis_Homo sapiens_hsa049160.88100805
57Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87397422
58Phototransduction_Homo sapiens_hsa047440.87220547
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86945400
60Ribosome_Homo sapiens_hsa030100.86649378
61Oxytocin signaling pathway_Homo sapiens_hsa049210.85818675
62Inositol phosphate metabolism_Homo sapiens_hsa005620.85447826
63Amoebiasis_Homo sapiens_hsa051460.85181221
64Hedgehog signaling pathway_Homo sapiens_hsa043400.83439354
65Chemical carcinogenesis_Homo sapiens_hsa052040.82878107
66Renin-angiotensin system_Homo sapiens_hsa046140.82068825
67Long-term depression_Homo sapiens_hsa047300.79043993
68ErbB signaling pathway_Homo sapiens_hsa040120.78487831
69Fatty acid biosynthesis_Homo sapiens_hsa000610.75585052
70MAPK signaling pathway_Homo sapiens_hsa040100.73762342
71MicroRNAs in cancer_Homo sapiens_hsa052060.73757031
72Steroid hormone biosynthesis_Homo sapiens_hsa001400.73324340
73Dilated cardiomyopathy_Homo sapiens_hsa054140.72265654
74Renal cell carcinoma_Homo sapiens_hsa052110.71958071
75Salivary secretion_Homo sapiens_hsa049700.69849830
76Glioma_Homo sapiens_hsa052140.67269142
77Vibrio cholerae infection_Homo sapiens_hsa051100.67015151
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.66584925
79Pertussis_Homo sapiens_hsa051330.66565852
80Hepatitis C_Homo sapiens_hsa051600.65699674
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.65493631
82Gastric acid secretion_Homo sapiens_hsa049710.65239992
83Small cell lung cancer_Homo sapiens_hsa052220.63576399
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62776521
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.61912883
86PPAR signaling pathway_Homo sapiens_hsa033200.61519120
87Pancreatic secretion_Homo sapiens_hsa049720.60897929
88beta-Alanine metabolism_Homo sapiens_hsa004100.60816242
89p53 signaling pathway_Homo sapiens_hsa041150.59613650
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.59433660
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.59372254
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.58716861
93Graft-versus-host disease_Homo sapiens_hsa053320.58702009
94Rap1 signaling pathway_Homo sapiens_hsa040150.58435336
95NF-kappa B signaling pathway_Homo sapiens_hsa040640.58431847
96Toxoplasmosis_Homo sapiens_hsa051450.58180245
97Salmonella infection_Homo sapiens_hsa051320.57908516
98FoxO signaling pathway_Homo sapiens_hsa040680.57669069
99Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.57318188
100Influenza A_Homo sapiens_hsa051640.56802478
101Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55361557
102Calcium signaling pathway_Homo sapiens_hsa040200.55149608
103Notch signaling pathway_Homo sapiens_hsa043300.54995575
104Insulin resistance_Homo sapiens_hsa049310.54051133
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.53801339
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.53520074
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53142369
108Collecting duct acid secretion_Homo sapiens_hsa049660.52607243
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.52473530
110Long-term potentiation_Homo sapiens_hsa047200.52314797
111Caffeine metabolism_Homo sapiens_hsa002320.51413949
112Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.50925499
113African trypanosomiasis_Homo sapiens_hsa051430.50819299
114Protein digestion and absorption_Homo sapiens_hsa049740.49938637
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.49745346
116Osteoclast differentiation_Homo sapiens_hsa043800.48588938
117Shigellosis_Homo sapiens_hsa051310.48573833
118Measles_Homo sapiens_hsa051620.48354516
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48347419
120Synaptic vesicle cycle_Homo sapiens_hsa047210.47165037
121Thyroid cancer_Homo sapiens_hsa052160.46768692
122Serotonergic synapse_Homo sapiens_hsa047260.46172081
123Insulin signaling pathway_Homo sapiens_hsa049100.44454547
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44131208
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44006167
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43026330
127Tuberculosis_Homo sapiens_hsa051520.42512828
128HTLV-I infection_Homo sapiens_hsa051660.42404285
129HIF-1 signaling pathway_Homo sapiens_hsa040660.40994615
130NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40829496
131Pathways in cancer_Homo sapiens_hsa052000.40785583
132Estrogen signaling pathway_Homo sapiens_hsa049150.40352041
133Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39910367
134Glutamatergic synapse_Homo sapiens_hsa047240.34935802
135TNF signaling pathway_Homo sapiens_hsa046680.34074592
136Mineral absorption_Homo sapiens_hsa049780.30856195
137Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.29410546
138Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.24862652
139Fructose and mannose metabolism_Homo sapiens_hsa000510.24109188
140Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.22822953
141Malaria_Homo sapiens_hsa051440.21269144

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