CR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of B cell receptor signaling pathway (GO:0050855)8.90010719
2antigen processing and presentation of endogenous antigen (GO:0019883)8.32563922
3regulation of interferon-beta biosynthetic process (GO:0045357)6.97821757
4positive regulation of gamma-delta T cell activation (GO:0046645)6.81040999
5cellular response to interleukin-15 (GO:0071350)6.63208366
6regulation of B cell differentiation (GO:0045577)6.29297479
7response to interleukin-15 (GO:0070672)6.26250322
8negative regulation of calcium ion transport into cytosol (GO:0010523)6.03528640
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.64967005
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.64967005
11negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)5.64635064
12* B cell proliferation (GO:0042100)5.46931548
13positive thymic T cell selection (GO:0045059)5.21198765
14mature B cell differentiation (GO:0002335)5.16691825
15regulation of gamma-delta T cell differentiation (GO:0045586)5.11961839
16regulation of antigen processing and presentation (GO:0002577)5.05940563
17regulation of antigen receptor-mediated signaling pathway (GO:0050854)5.04274590
18cellular response to zinc ion (GO:0071294)5.01657503
19positive regulation of B cell differentiation (GO:0045579)4.99298931
20negative regulation of B cell proliferation (GO:0030889)4.95224968
21positive regulation of interferon-gamma biosynthetic process (GO:0045078)4.87437087
22regulation of gamma-delta T cell activation (GO:0046643)4.78105559
23positive regulation of interferon-alpha production (GO:0032727)4.75820502
24regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.73809699
25B cell mediated immunity (GO:0019724)4.67375005
26antigen receptor-mediated signaling pathway (GO:0050851)4.66867823
27regulation of B cell proliferation (GO:0030888)4.66738145
28positive regulation of Rap GTPase activity (GO:0032854)4.65032111
29I-kappaB phosphorylation (GO:0007252)4.50290269
30regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.48315651
31regulation of interferon-alpha production (GO:0032647)4.42931967
32CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)4.31334431
33negative regulation of bone resorption (GO:0045779)4.31011943
34positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.30868693
35positive regulation of humoral immune response (GO:0002922)4.29947952
36positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.28757295
37lymph node development (GO:0048535)4.26882464
38defense response to protozoan (GO:0042832)4.23697807
39negative regulation of histone methylation (GO:0031061)4.13784855
40regulation of dendritic cell antigen processing and presentation (GO:0002604)4.06443520
41antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.04011282
42regulation of alpha-beta T cell proliferation (GO:0046640)4.01468347
43* B cell activation (GO:0042113)3.93126979
44regulation of Rap GTPase activity (GO:0032317)3.92278465
45regulation of B cell apoptotic process (GO:0002902)3.92238812
46detection of bacterium (GO:0016045)3.88491040
47* immune response-activating cell surface receptor signaling pathway (GO:0002429)3.87098742
48positive regulation of B cell proliferation (GO:0030890)3.87052217
49thymic T cell selection (GO:0045061)3.86273618
50type I interferon signaling pathway (GO:0060337)3.82476303
51cellular response to type I interferon (GO:0071357)3.82476303
52response to type I interferon (GO:0034340)3.81734632
53T cell migration (GO:0072678)3.75988773
54regulation of interferon-gamma biosynthetic process (GO:0045072)3.72761344
55regulation of T-helper 1 cell differentiation (GO:0045625)3.72561938
56negative thymic T cell selection (GO:0045060)3.69864414
57B cell homeostasis (GO:0001782)3.69647208
58T-helper 1 type immune response (GO:0042088)3.67040452
59regulation of interleukin-12 biosynthetic process (GO:0045075)3.65460222
60positive T cell selection (GO:0043368)3.64229807
61negative regulation of nitric-oxide synthase activity (GO:0051001)3.61299556
62NIK/NF-kappaB signaling (GO:0038061)3.58059929
63positive regulation of interleukin-2 production (GO:0032743)3.57250966
64regulation of cellular extravasation (GO:0002691)3.56541221
65detection of other organism (GO:0098543)3.53061763
66T cell selection (GO:0045058)3.49664880
67negative regulation of synaptic transmission, GABAergic (GO:0032229)3.48280921
68negative regulation of bone remodeling (GO:0046851)3.48025456
69T cell lineage commitment (GO:0002360)3.47173960
70interferon-gamma-mediated signaling pathway (GO:0060333)3.43358532
71macrophage activation involved in immune response (GO:0002281)3.42855369
72positive regulation of neutrophil chemotaxis (GO:0090023)3.40936578
73positive regulation of neutrophil migration (GO:1902624)3.40936578
74regulation of MHC class I biosynthetic process (GO:0045343)3.40207409
75response to protozoan (GO:0001562)3.39820700
76positive regulation of antigen processing and presentation (GO:0002579)3.39814536
77negative regulation of mast cell activation (GO:0033004)3.39486269
78negative regulation of cell killing (GO:0031342)3.39269093
79negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.39269093
80positive regulation of macrophage cytokine production (GO:0060907)3.37874853
81negative T cell selection (GO:0043383)3.35558524
82positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.33701203
83positive regulation of immunoglobulin production (GO:0002639)3.33577571
84lymphocyte homeostasis (GO:0002260)3.32392264
85adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli3.31656922
86regulation of B cell activation (GO:0050864)3.31376409
87myeloid dendritic cell activation (GO:0001773)3.29877816
88myeloid dendritic cell differentiation (GO:0043011)3.28787198
89cellular response to interferon-gamma (GO:0071346)3.27740021
90positive regulation of alpha-beta T cell proliferation (GO:0046641)3.24840539
91regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.22958095
92positive regulation of cell adhesion mediated by integrin (GO:0033630)3.22400305
93positive regulation of B cell activation (GO:0050871)3.22066642
94cytidine metabolic process (GO:0046087)3.20428041
95cytidine catabolic process (GO:0006216)3.20428041
96cytidine deamination (GO:0009972)3.20428041
97negative regulation of B cell apoptotic process (GO:0002903)3.18419746
98positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.18215344
99modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.17800369
100positive regulation by organism of defense response of other organism involved in symbiotic interact3.17800369
101modulation by symbiont of host immune response (GO:0052553)3.17800369
102positive regulation by symbiont of host defense response (GO:0052509)3.17800369
103modulation by symbiont of host defense response (GO:0052031)3.17800369
104modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.17800369
105antibacterial humoral response (GO:0019731)3.15931342
106respiratory burst (GO:0045730)3.15221617
107mature B cell differentiation involved in immune response (GO:0002313)3.14899298
108regulation of T cell receptor signaling pathway (GO:0050856)3.14828054
109cellular response to exogenous dsRNA (GO:0071360)3.13455405
110negative regulation of toll-like receptor signaling pathway (GO:0034122)3.12227677
111positive regulation of interferon-beta production (GO:0032728)3.11999293
112JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.10477170
113regulation of histone H3-K27 methylation (GO:0061085)3.08567551
114locomotory exploration behavior (GO:0035641)3.08426432
115pyrimidine ribonucleoside catabolic process (GO:0046133)3.05045101
116antimicrobial humoral response (GO:0019730)3.04048328
117* lymphocyte proliferation (GO:0046651)3.03024143
118positive regulation of granulocyte chemotaxis (GO:0071624)3.02774677
119T cell costimulation (GO:0031295)3.01877477
120neutrophil activation (GO:0042119)2.99843965
121* mononuclear cell proliferation (GO:0032943)2.99819853
122Peyers patch development (GO:0048541)2.99327382
123mucosal-associated lymphoid tissue development (GO:0048537)2.99327382
124histamine secretion (GO:0001821)2.98867619
125germinal center formation (GO:0002467)2.98722336
126positive regulation of interleukin-12 production (GO:0032735)2.98703370
127* immune response-activating signal transduction (GO:0002757)2.98508221
128immunoglobulin mediated immune response (GO:0016064)2.97893489
129negative regulation of alpha-beta T cell activation (GO:0046636)2.96316529
130negative regulation of T cell receptor signaling pathway (GO:0050860)2.95607556
131lymphocyte costimulation (GO:0031294)2.94716582
132histone H3-K4 trimethylation (GO:0080182)2.94306303
133adaptive immune response (GO:0002250)2.91506539
134dendritic cell chemotaxis (GO:0002407)2.90564039
135positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.90545431
136positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.88796677
137positive regulation of Cdc42 GTPase activity (GO:0043089)2.88619827
138regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.86832914
139production of molecular mediator of immune response (GO:0002440)2.83983180
140response to interferon-gamma (GO:0034341)2.82670585
141B cell receptor signaling pathway (GO:0050853)10.3937760

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human8.92792419
2IRF8_22096565_ChIP-ChIP_GC-B_Mouse5.40327411
3MYC_22102868_ChIP-Seq_BL_Human4.71297288
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.51921493
5IRF8_21731497_ChIP-ChIP_J774_Mouse4.49405380
6SPI1_22096565_ChIP-ChIP_GC-B_Mouse4.47837048
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.61317523
8IRF8_27001747_Chip-Seq_BMDM_Mouse3.58683993
9VDR_21846776_ChIP-Seq_THP-1_Human3.29094635
10* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.24780191
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.22656289
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.13847278
13GATA1_22025678_ChIP-Seq_K562_Human3.00406968
14FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.68147876
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.61915993
16MYB_26560356_Chip-Seq_TH1_Human2.52438906
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.49854918
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.49166464
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.47964307
20SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.47332758
21* RUNX_20019798_ChIP-Seq_JUKART_Human2.46300239
22IKZF1_21737484_ChIP-ChIP_HCT116_Human2.42379114
23MYB_26560356_Chip-Seq_TH2_Human2.36239136
24VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.34118762
25MAF_26560356_Chip-Seq_TH1_Human2.33327205
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.32637371
27NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.27129712
28STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.26787021
29* UTX_26944678_Chip-Seq_JUKART_Human2.14157941
30* VDR_24763502_ChIP-Seq_THP-1_Human2.12942933
31TCF7_22412390_ChIP-Seq_EML_Mouse2.08665082
32ELF1_17652178_ChIP-ChIP_JURKAT_Human2.03565235
33CIITA_25753668_ChIP-Seq_RAJI_Human2.03464933
34ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.02213317
35* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.96291265
36SPI1_23547873_ChIP-Seq_NB4_Human1.93668545
37KDM2B_26808549_Chip-Seq_DND41_Human1.93588959
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.90847061
39* NOTCH1_21737748_ChIP-Seq_TLL_Human1.85353291
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.78700978
41E2F4_17652178_ChIP-ChIP_JURKAT_Human1.77340246
42SPI1_23127762_ChIP-Seq_K562_Human1.67105025
43* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.66001572
44SCL_19346495_ChIP-Seq_HPC-7_Human1.65287629
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.63650181
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.61604446
47* GATA3_27048872_Chip-Seq_THYMUS_Human1.60142793
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.58931470
49MAF_26560356_Chip-Seq_TH2_Human1.58586006
50MYB_21317192_ChIP-Seq_ERMYB_Mouse1.50744572
51RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.48909284
52ELK3_25401928_ChIP-Seq_HUVEC_Human1.45348905
53NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.42495956
54* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.39605398
55SMAD_19615063_ChIP-ChIP_OVARY_Human1.38399819
56PU.1_20513432_ChIP-Seq_Bcells_Mouse1.37295986
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30523290
58GATA3_26560356_Chip-Seq_TH2_Human1.27894696
59KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25157428
60GATA2_22383799_ChIP-Seq_G1ME_Mouse1.24790856
61FOXM1_23109430_ChIP-Seq_U2OS_Human1.21086384
62PU_27001747_Chip-Seq_BMDM_Mouse1.18647980
63GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15644533
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.12111226
65GATA1_19941827_ChIP-Seq_MEL_Mouse1.10286579
66EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.10268139
67BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09483229
68* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09406932
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09182027
70LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07564090
71FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.03662807
72LXR_22292898_ChIP-Seq_THP-1_Human1.02743525
73CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00783631
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97686487
75ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96992992
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96579090
77LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96517531
78SMRT_27268052_Chip-Seq_Bcells_Human0.95642965
79EGR1_23403033_ChIP-Seq_LIVER_Mouse0.94792012
80RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.93108932
81FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92995939
82EZH2_22144423_ChIP-Seq_EOC_Human0.90890216
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90289339
84HOXB4_20404135_ChIP-ChIP_EML_Mouse0.90272717
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89924977
86KDM2B_26808549_Chip-Seq_JURKAT_Human0.89884696
87TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.86202580
88ETS1_22383799_ChIP-Seq_G1ME_Mouse0.85071380
89VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.84287510
90NCOR1_26117541_ChIP-Seq_K562_Human0.83802499
91SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.83623774
92GATA2_19941826_ChIP-Seq_K562_Human0.83599478
93VDR_24787735_ChIP-Seq_THP-1_Human0.83430218
94E2F1_21310950_ChIP-Seq_MCF-7_Human0.83093309
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82118143
96BCL6_27268052_Chip-Seq_Bcells_Human0.82032157
97SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.81687247
98GATA3_26560356_Chip-Seq_TH1_Human0.81613545
99IRF1_19129219_ChIP-ChIP_H3396_Human0.80277289
100FOXP3_21729870_ChIP-Seq_TREG_Human0.79307757
101P300_27268052_Chip-Seq_Bcells_Human0.78846346
102PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78405107
103VDR_23849224_ChIP-Seq_CD4+_Human0.76708132
104CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.76360854
105ETS1_21867929_ChIP-Seq_TH2_Mouse0.74885688
106ELK4_26923725_Chip-Seq_MESODERM_Mouse0.74311909
107BCOR_27268052_Chip-Seq_Bcells_Human0.69974381
108* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.69593018
109PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69502628
110SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.69347181
111RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.68556144
112FOXO3_23340844_ChIP-Seq_DLD1_Human0.68448546
113GATA1_19941826_ChIP-Seq_K562_Human0.66534130
114SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.66009019
115KDM5A_27292631_Chip-Seq_BREAST_Human0.65178997
116ELF1_20517297_ChIP-Seq_JURKAT_Human0.65162603
117Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.64605301
118E2F7_22180533_ChIP-Seq_HELA_Human0.64536998
119ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.63689659
120* CTCF_26484167_Chip-Seq_Bcells_Mouse0.61174583
121CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.61081727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation6.58136954
2MP0001790_abnormal_immune_system5.60378708
3MP0005387_immune_system_phenotype5.60378708
4* MP0001800_abnormal_humoral_immune5.18729867
5MP0002452_abnormal_antigen_presenting3.93533968
6* MP0005000_abnormal_immune_tolerance3.59558846
7MP0002723_abnormal_immune_serum3.22149697
8* MP0002420_abnormal_adaptive_immunity3.09326037
9MP0003303_peritoneal_inflammation3.01245220
10* MP0000685_abnormal_immune_system3.00891597
11MP0001819_abnormal_immune_cell2.99872127
12* MP0002398_abnormal_bone_marrow2.79145434
13MP0005671_abnormal_response_to2.72802642
14MP0000716_abnormal_immune_system2.68763463
15MP0000689_abnormal_spleen_morphology2.67475177
16MP0003763_abnormal_thymus_physiology2.44800544
17MP0001873_stomach_inflammation2.37581744
18MP0005645_abnormal_hypothalamus_physiol2.21749109
19MP0003183_abnormal_peptide_metabolism2.16401455
20MP0002429_abnormal_blood_cell2.13839400
21MP0009785_altered_susceptibility_to2.08933892
22MP0002419_abnormal_innate_immunity2.03650668
23MP0005025_abnormal_response_to2.02769571
24MP0002722_abnormal_immune_system2.02345720
25MP0000569_abnormal_digit_pigmentation1.96559642
26MP0003300_gastrointestinal_ulcer1.96265230
27MP0002396_abnormal_hematopoietic_system1.94988709
28MP0005360_urolithiasis1.94978454
29MP0002405_respiratory_system_inflammati1.89792566
30MP0002166_altered_tumor_susceptibility1.87997719
31MP0002909_abnormal_adrenal_gland1.87120558
32MP0004510_myositis1.80473344
33MP0001845_abnormal_inflammatory_respons1.79093906
34MP0002139_abnormal_hepatobiliary_system1.77742062
35MP0001853_heart_inflammation1.69266417
36MP0002148_abnormal_hypersensitivity_rea1.63465431
37MP0005174_abnormal_tail_pigmentation1.60679979
38MP0008260_abnormal_autophagy1.54554203
39MP0010234_abnormal_vibrissa_follicle1.53534646
40MP0004808_abnormal_hematopoietic_stem1.52775157
41MP0003724_increased_susceptibility_to1.47026870
42MP0003787_abnormal_imprinting1.44509842
43MP0010155_abnormal_intestine_physiology1.43956555
44MP0000490_abnormal_crypts_of1.40687927
45MP0005310_abnormal_salivary_gland1.39639664
46MP0003693_abnormal_embryo_hatching1.35616177
47MP0003091_abnormal_cell_migration1.30047873
48MP0002136_abnormal_kidney_physiology1.28354338
49MP0001666_abnormal_nutrient_absorption1.26535949
50MP0010094_abnormal_chromosome_stability1.25902052
51MP0003436_decreased_susceptibility_to1.24536568
52MP0008874_decreased_physiological_sensi1.21230666
53MP0001348_abnormal_lacrimal_gland1.21224510
54MP0003866_abnormal_defecation1.19918436
55MP0002006_tumorigenesis1.19774344
56MP0003045_fibrosis1.15444081
57MP0000703_abnormal_thymus_morphology1.13835381
58MP0004947_skin_inflammation1.13030757
59MP0002928_abnormal_bile_duct1.12045221
60MP0005464_abnormal_platelet_physiology1.08837032
61MP0008469_abnormal_protein_level1.05560212
62MP0008057_abnormal_DNA_replication1.05270767
63MP0002009_preneoplasia1.02509161
64MP0003111_abnormal_nucleus_morphology0.99968553
65MP0009333_abnormal_splenocyte_physiolog0.99348608
66MP0003172_abnormal_lysosome_physiology0.94246474
67MP0000465_gastrointestinal_hemorrhage0.91390037
68MP0009840_abnormal_foam_cell0.91105566
69MP0009764_decreased_sensitivity_to0.90318449
70MP0004381_abnormal_hair_follicle0.88485354
71MP0003252_abnormal_bile_duct0.87885788
72MP0000015_abnormal_ear_pigmentation0.87329168
73MP0002095_abnormal_skin_pigmentation0.86293105
74MP0010352_gastrointestinal_tract_polyps0.82270618
75MP0002933_joint_inflammation0.80866886
76MP0010307_abnormal_tumor_latency0.78952397
77MP0004264_abnormal_extraembryonic_tissu0.78037971
78MP0008961_abnormal_basal_metabolism0.77719707
79MP0001879_abnormal_lymphatic_vessel0.77129513
80MP0000313_abnormal_cell_death0.74033452
81MP0000767_abnormal_smooth_muscle0.71341007
82MP0003566_abnormal_cell_adhesion0.70333840
83MP0002138_abnormal_hepatobiliary_system0.70186078
84MP0003868_abnormal_feces_composition0.69945448
85MP0003718_maternal_effect0.68852529
86MP0000858_altered_metastatic_potential0.68517918
87MP0004782_abnormal_surfactant_physiolog0.68186059
88MP0002277_abnormal_respiratory_mucosa0.64690473
89MP0005085_abnormal_gallbladder_physiolo0.64683792
90MP0002019_abnormal_tumor_incidence0.63736083
91MP0000371_diluted_coat_color0.63653381
92MP0004957_abnormal_blastocyst_morpholog0.63317322
93MP0000249_abnormal_blood_vessel0.62520134
94MP0000477_abnormal_intestine_morphology0.62040500
95MP0005451_abnormal_body_composition0.59232792
96MP0002254_reproductive_system_inflammat0.59203151
97MP0003191_abnormal_cellular_cholesterol0.58789224
98MP0003690_abnormal_glial_cell0.57993726
99MP0000604_amyloidosis0.57519494
100MP0005621_abnormal_cell_physiology0.57341185
101MP0003453_abnormal_keratinocyte_physiol0.57241259
102MP0002163_abnormal_gland_morphology0.57061117
103MP0002168_other_aberrant_phenotype0.56773443
104MP0001730_embryonic_growth_arrest0.55066538
105MP0002693_abnormal_pancreas_physiology0.54711413
106MP0009763_increased_sensitivity_to0.54360317
107MP0001764_abnormal_homeostasis0.52435425
108* MP0005166_decreased_susceptibility_to0.52358104
109MP0005075_abnormal_melanosome_morpholog0.52182290
110MP0002998_abnormal_bone_remodeling0.51478468
111MP0001663_abnormal_digestive_system0.49774959
112MP0002135_abnormal_kidney_morphology0.47136584
113MP0009115_abnormal_fat_cell0.46741738
114MP0001186_pigmentation_phenotype0.46226419
115MP0004019_abnormal_vitamin_homeostasis0.44883368
116MP0000609_abnormal_liver_physiology0.44802513
117MP0005381_digestive/alimentary_phenotyp0.44697069
118MP0009643_abnormal_urine_homeostasis0.44159981
119MP0005584_abnormal_enzyme/coenzyme_acti0.43481293
120MP0001986_abnormal_taste_sensitivity0.42316749
121MP0000350_abnormal_cell_proliferation0.39945327
122MP0002083_premature_death0.36990556
123MP0005257_abnormal_intraocular_pressure0.36916284
124MP0001533_abnormal_skeleton_physiology0.36049776
125MP0010630_abnormal_cardiac_muscle0.35670518
126MP0003279_aneurysm0.34891475
127MP0001958_emphysema0.34800058
128MP0002075_abnormal_coat/hair_pigmentati0.34254307
129MP0008569_lethality_at_weaning0.33098640
130MP0005384_cellular_phenotype0.32870580
131MP0003077_abnormal_cell_cycle0.32187163
132MP0006082_CNS_inflammation0.31879492

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)9.77501607
2* Gastrointestinal stroma tumor (HP:0100723)9.13703883
3Recurrent sinusitis (HP:0011108)6.92324951
4Recurrent bronchitis (HP:0002837)6.74016799
5Colitis (HP:0002583)6.31301164
6Cellulitis (HP:0100658)5.63716327
7* Emphysema (HP:0002097)5.41046804
8IgM deficiency (HP:0002850)5.30992140
9Inflammation of the large intestine (HP:0002037)5.30427096
10Abnormal delayed hypersensitivity skin test (HP:0002963)5.15479587
11* Lymphopenia (HP:0001888)5.09329451
12Gastrointestinal inflammation (HP:0004386)5.01679915
13Recurrent viral infections (HP:0004429)4.95194157
14Panhypogammaglobulinemia (HP:0003139)4.86145270
15* Abnormality of cells of the lymphoid lineage (HP:0012140)4.78172010
16Chronic sinusitis (HP:0011109)4.70991654
17Papilloma (HP:0012740)4.69977778
18Verrucae (HP:0200043)4.69977778
19Meningitis (HP:0001287)4.35859951
20* Vasculitis (HP:0002633)4.22459716
21Chronic otitis media (HP:0000389)4.21719882
22Recurrent otitis media (HP:0000403)4.19294185
23* Restrictive lung disease (HP:0002091)4.18681813
24Recurrent pneumonia (HP:0006532)3.86833232
25Bronchitis (HP:0012387)3.81913381
26Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.76982267
27Recurrent bacterial skin infections (HP:0005406)3.76978109
28Chronic mucocutaneous candidiasis (HP:0002728)3.71233603
29Recurrent cutaneous fungal infections (HP:0011370)3.71233603
30Recurrent lower respiratory tract infections (HP:0002783)3.69409588
31Recurrent abscess formation (HP:0002722)3.64539452
32Mediastinal lymphadenopathy (HP:0100721)3.52968524
33Osteomyelitis (HP:0002754)3.48782776
34Mitral stenosis (HP:0001718)3.47733390
35Abnormality of the fingertips (HP:0001211)3.32612803
36Recurrent fungal infections (HP:0002841)3.29023145
37Papilledema (HP:0001085)3.25601310
38Recurrent skin infections (HP:0001581)3.23199839
39Viral hepatitis (HP:0006562)3.18849428
40Malnutrition (HP:0004395)3.05279852
41Increased IgM level (HP:0003496)3.02064815
42Small epiphyses (HP:0010585)2.96335578
43Sepsis (HP:0100806)2.95380117
44Abnormality of the prostate (HP:0008775)2.87768195
45Abnormality of macrophages (HP:0004311)2.85973901
46Urticaria (HP:0001025)2.85863588
47* Leukopenia (HP:0001882)2.84726720
48Autoimmune thrombocytopenia (HP:0001973)2.77133200
49Eczematoid dermatitis (HP:0000976)2.74970032
50Abnormality of T cell physiology (HP:0011840)2.70401912
51* Lymphoma (HP:0002665)2.61469550
52Premature loss of primary teeth (HP:0006323)2.61232392
53Abnormality of T cells (HP:0002843)2.56298621
54Periodontitis (HP:0000704)2.47363951
55Hypoplasia of the capital femoral epiphysis (HP:0003090)2.42370739
56Resting tremor (HP:0002322)2.41784175
57* IgA deficiency (HP:0002720)2.38035303
58Abnormality of glutamine family amino acid metabolism (HP:0010902)2.37663523
59Vertebral arch anomaly (HP:0008438)2.33068664
60Autoimmune hemolytic anemia (HP:0001890)2.32125755
61B lymphocytopenia (HP:0010976)2.31908524
62Abnormality of B cell number (HP:0010975)2.31908524
63Hypergammaglobulinemia (HP:0010702)2.29114670
64Thrombocytosis (HP:0001894)2.27971452
65Fatigue (HP:0012378)2.27959277
66T lymphocytopenia (HP:0005403)2.26315100
67Encephalitis (HP:0002383)2.25513595
68Nasal polyposis (HP:0100582)2.25191968
69Skin ulcer (HP:0200042)2.24444329
70Combined immunodeficiency (HP:0005387)2.24180321
71Severe combined immunodeficiency (HP:0004430)2.23942264
72Pulmonary infiltrates (HP:0002113)2.23703179
73Chronic obstructive pulmonary disease (HP:0006510)2.22170922
74Obstructive lung disease (HP:0006536)2.22170922
75Elevated erythrocyte sedimentation rate (HP:0003565)2.20886661
76Pustule (HP:0200039)2.19951641
77Gastrointestinal infarctions (HP:0005244)2.16968388
78Granulocytopenia (HP:0001913)2.15894111
79Abnormality of T cell number (HP:0011839)2.15386188
80Abnormality of small intestinal villus morphology (HP:0011472)2.13660033
81Villous atrophy (HP:0011473)2.13660033
82Hypertensive crisis (HP:0100735)2.12717195
83Recurrent gram-negative bacterial infections (HP:0005420)2.09448651
84Systemic lupus erythematosus (HP:0002725)2.09394824
85Xerostomia (HP:0000217)2.08196761
86* Arthralgia (HP:0002829)2.06104337
87Hematochezia (HP:0002573)2.05838211
88Myocardial infarction (HP:0001658)2.05176213
89IgG deficiency (HP:0004315)2.03555753
90Thyroiditis (HP:0100646)2.03467350
91Abnormality of male internal genitalia (HP:0000022)2.00699520
92Abnormality of the pleura (HP:0002103)2.00075894
93Acrocyanosis (HP:0001063)1.99848719
94Hypoplasia of the thymus (HP:0000778)1.98506167
95Skin rash (HP:0000988)1.97474762
96Macroorchidism (HP:0000053)1.96472819
97Aplasia/Hypoplasia of the thymus (HP:0010515)1.95070689
98Flattened epiphyses (HP:0003071)1.94782120
99Hemoptysis (HP:0002105)1.94304414
100Pulmonary fibrosis (HP:0002206)1.94239398
101Absent epiphyses (HP:0010577)1.90220620
102Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.90220620
103Prostate neoplasm (HP:0100787)1.84851121
104Hepatitis (HP:0012115)1.84257951
105Ulnar bowing (HP:0003031)1.82900158
106Teleangiectasia of the skin (HP:0100585)1.82865341
107Spinal cord lesions (HP:0100561)1.82815382
108Syringomyelia (HP:0003396)1.82815382
109Spontaneous hematomas (HP:0007420)1.81883822
110Interstitial pulmonary disease (HP:0006530)1.81183921
111Abnormality of the nasal mucosa (HP:0000433)1.79277359
112Chest pain (HP:0100749)1.78271796
113Increased IgE level (HP:0003212)1.77864608
114Irregular vertebral endplates (HP:0003301)1.76498817
115Eosinophilia (HP:0001880)1.75126002
116Absent frontal sinuses (HP:0002688)1.73332195
117Bronchiectasis (HP:0002110)1.72710457
118Petechiae (HP:0000967)1.72629677
119Abnormality of the peritoneum (HP:0002585)1.69680990
120Facial diplegia (HP:0001349)1.68803755
121Amaurosis fugax (HP:0100576)1.67557198
122Neutropenia (HP:0001875)1.67344767
123Cerebral aneurysm (HP:0004944)1.61130238
124Arthropathy (HP:0003040)1.59802941
125Gingivitis (HP:0000230)1.57586641
126* Chronic diarrhea (HP:0002028)1.52188242
127Aqueductal stenosis (HP:0002410)1.51851258
128Gingival bleeding (HP:0000225)1.48779574
129Basal cell carcinoma (HP:0002671)1.47075297

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K17.30601287
2MAP3K133.71397012
3PRPF4B3.68520306
4SMG13.11925562
5CSF1R3.11301258
6JAK13.08073539
7ERN12.99541226
8BTK2.75475248
9SIK22.71251262
10MAP3K142.67520058
11LRRK22.64983956
12GRK62.62149493
13GRK12.58196493
14BLK2.47085693
15SYK2.46858907
16RIPK42.22049969
17STK102.21239380
18TYK22.10164851
19FRK1.79754515
20CDK121.79547069
21IRAK31.69761218
22PASK1.67677218
23CSK1.67291132
24SIK31.61867615
25LYN1.60644478
26NEK91.60257877
27HCK1.57557913
28MARK31.46161326
29KIT1.41851418
30VRK11.40112828
31MAP3K101.39849701
32TAF11.38172643
33BRD41.35110675
34JAK31.32803159
35MATK1.29980994
36IRAK41.28331546
37STK241.25542649
38MST41.24449259
39CDC42BPA1.20709503
40IKBKB1.19617801
41TGFBR21.14031956
42SIK11.12089968
43TLK11.11475907
44MAP3K91.07738308
45PRKCQ1.04206443
46ITK1.02616899
47LCK1.00622591
48CDK190.98528441
49FES0.96586356
50NLK0.96421323
51MAPK110.96089292
52TBK10.94931356
53ACVR1B0.93661869
54VRK20.93138209
55TEC0.93006671
56ALK0.91415215
57CLK10.84525480
58PRKCH0.81163903
59FGFR30.80040199
60ABL10.79963002
61FGFR40.79411763
62TNK20.79153989
63FGR0.77996008
64IKBKE0.77562363
65CAMK1G0.77069339
66EEF2K0.76445606
67ZAP700.74820423
68WNK10.74606086
69TRIB30.72865521
70CSNK1A1L0.72030192
71CHUK0.71694897
72HIPK20.70416115
73MAP3K70.63627364
74INSR0.63256246
75MAP3K80.62862312
76TESK20.62655472
77CDC70.60447706
78PDK10.60257143
79DAPK30.60145959
80PRKD20.56938841
81RPS6KA50.55192171
82CAMK1D0.54079025
83FYN0.53050639
84MAPK70.52907787
85ARAF0.50403757
86TAOK30.50365551
87KDR0.49465961
88ZAK0.48862860
89PIM10.47717064
90PTK60.47439842
91CDK90.45697898
92BMPR20.44487881
93STK40.43698971
94PRKD10.43652191
95JAK20.42485289
96ERBB30.41919528
97MAP3K10.41852296
98TXK0.39289190
99EGFR0.38805894
100BRAF0.38796316
101MAPK40.37790610
102PRKCI0.37337363
103SGK30.37133257
104IRAK10.35183616
105EIF2AK30.34920648
106MAPK120.33707953
107CDK40.32798456
108EPHB10.32633376
109MAPKAPK20.31866162
110CSNK1A10.30609278
111RPS6KA40.30124932
112CDK70.28357208
113CCNB10.27845405
114EPHA30.27785238
115TTN0.26450538
116CSNK1G30.25798341
117CSNK1G10.25522852
118CHEK10.25256120
119IGF1R0.23454734
120PKN10.23060793
121MAP2K10.23055251
122MARK20.21868178
123YES10.20881802
124CSNK1G20.20682884
125DYRK1A0.20631487
126DYRK1B0.20361902
127SRC0.17752222
128STK110.17541987
129CSNK1D0.17038566
130MELK0.16795173
131PRKCD0.16474255
132KSR20.15914960
133PRKAA20.15682404
134PDPK10.15533706
135CDK60.14382381

Predicted pathways (KEGG)

RankGene SetZ-score
1* B cell receptor signaling pathway_Homo sapiens_hsa046626.88262453
2Primary immunodeficiency_Homo sapiens_hsa053406.49437855
3Allograft rejection_Homo sapiens_hsa053304.63709731
4Autoimmune thyroid disease_Homo sapiens_hsa053204.38588523
5Asthma_Homo sapiens_hsa053104.29757999
6* Hematopoietic cell lineage_Homo sapiens_hsa046404.23619056
7Graft-versus-host disease_Homo sapiens_hsa053324.03967979
8Type I diabetes mellitus_Homo sapiens_hsa049403.53967927
9NF-kappa B signaling pathway_Homo sapiens_hsa040643.18599038
10Systemic lupus erythematosus_Homo sapiens_hsa053222.85901990
11Staphylococcus aureus infection_Homo sapiens_hsa051502.35026820
12Osteoclast differentiation_Homo sapiens_hsa043802.27550691
13Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.07479129
14Antigen processing and presentation_Homo sapiens_hsa046121.98706589
15T cell receptor signaling pathway_Homo sapiens_hsa046601.96797902
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.93391651
17Leishmaniasis_Homo sapiens_hsa051401.87399613
18Chemokine signaling pathway_Homo sapiens_hsa040621.76183256
19Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.63799922
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.61847989
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.56653168
22Tuberculosis_Homo sapiens_hsa051521.53521297
23Herpes simplex infection_Homo sapiens_hsa051681.46546317
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.44397406
25African trypanosomiasis_Homo sapiens_hsa051431.41705453
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.40928111
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.36640623
28Cyanoamino acid metabolism_Homo sapiens_hsa004601.36095156
29Measles_Homo sapiens_hsa051621.34424786
30Platelet activation_Homo sapiens_hsa046111.25868275
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.24182713
32Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.20390252
33Lysine degradation_Homo sapiens_hsa003101.17685948
34Alcoholism_Homo sapiens_hsa050341.14788089
35Rheumatoid arthritis_Homo sapiens_hsa053231.12186409
36* Epstein-Barr virus infection_Homo sapiens_hsa051691.08991300
37Jak-STAT signaling pathway_Homo sapiens_hsa046301.07725831
38Toxoplasmosis_Homo sapiens_hsa051451.05803986
39Influenza A_Homo sapiens_hsa051641.05327546
40Notch signaling pathway_Homo sapiens_hsa043301.04267718
41Renin-angiotensin system_Homo sapiens_hsa046141.03968723
42Neurotrophin signaling pathway_Homo sapiens_hsa047221.01861941
43Non-small cell lung cancer_Homo sapiens_hsa052231.01584686
44Malaria_Homo sapiens_hsa051440.99250437
45Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98053131
46Viral myocarditis_Homo sapiens_hsa054160.96889519
47Apoptosis_Homo sapiens_hsa042100.96006011
48Hepatitis B_Homo sapiens_hsa051610.95656238
49Shigellosis_Homo sapiens_hsa051310.94390440
50Fat digestion and absorption_Homo sapiens_hsa049750.91461384
51TNF signaling pathway_Homo sapiens_hsa046680.88068028
52Chronic myeloid leukemia_Homo sapiens_hsa052200.85437099
53Pancreatic cancer_Homo sapiens_hsa052120.78415956
54Vitamin digestion and absorption_Homo sapiens_hsa049770.78004133
55Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75706481
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74415949
57Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73606545
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71949878
59Hepatitis C_Homo sapiens_hsa051600.70505197
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68313196
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.66146624
62Dorso-ventral axis formation_Homo sapiens_hsa043200.63506207
63Long-term potentiation_Homo sapiens_hsa047200.62977090
64MAPK signaling pathway_Homo sapiens_hsa040100.62372611
65Acute myeloid leukemia_Homo sapiens_hsa052210.61379443
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60890437
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60226247
68VEGF signaling pathway_Homo sapiens_hsa043700.60090069
69Small cell lung cancer_Homo sapiens_hsa052220.59646002
70HTLV-I infection_Homo sapiens_hsa051660.58269794
71Phagosome_Homo sapiens_hsa041450.57680607
72Non-homologous end-joining_Homo sapiens_hsa034500.57569656
73Proteoglycans in cancer_Homo sapiens_hsa052050.57053318
74DNA replication_Homo sapiens_hsa030300.52649554
75GnRH signaling pathway_Homo sapiens_hsa049120.52645459
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.52234910
77Fructose and mannose metabolism_Homo sapiens_hsa000510.52179384
78Viral carcinogenesis_Homo sapiens_hsa052030.50006897
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49966768
80Insulin resistance_Homo sapiens_hsa049310.49892773
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48204164
82Salmonella infection_Homo sapiens_hsa051320.46137502
83Pertussis_Homo sapiens_hsa051330.45636568
84Inositol phosphate metabolism_Homo sapiens_hsa005620.45087875
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.43850821
86ABC transporters_Homo sapiens_hsa020100.43208436
87Base excision repair_Homo sapiens_hsa034100.43167381
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.42485892
89Thyroid hormone synthesis_Homo sapiens_hsa049180.42043708
90Long-term depression_Homo sapiens_hsa047300.41136454
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.40515944
92Prolactin signaling pathway_Homo sapiens_hsa049170.38280971
93Gastric acid secretion_Homo sapiens_hsa049710.38085022
94MicroRNAs in cancer_Homo sapiens_hsa052060.37654913
95Salivary secretion_Homo sapiens_hsa049700.37589557
96Renin secretion_Homo sapiens_hsa049240.37524379
97Glioma_Homo sapiens_hsa052140.36897175
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36873236
99Mismatch repair_Homo sapiens_hsa034300.36430258
100Endocytosis_Homo sapiens_hsa041440.35473483
101Pancreatic secretion_Homo sapiens_hsa049720.35237315
102FoxO signaling pathway_Homo sapiens_hsa040680.34605540
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34427865
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34195406
105Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32731883
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.32617872
107mTOR signaling pathway_Homo sapiens_hsa041500.31432536
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30535734
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29729357
110Estrogen signaling pathway_Homo sapiens_hsa049150.29544445
111Glucagon signaling pathway_Homo sapiens_hsa049220.27761166
112Oxytocin signaling pathway_Homo sapiens_hsa049210.27735773
113Type II diabetes mellitus_Homo sapiens_hsa049300.27341167
114cGMP-PKG signaling pathway_Homo sapiens_hsa040220.26187708
115Rap1 signaling pathway_Homo sapiens_hsa040150.25742817
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.25647347
117Prostate cancer_Homo sapiens_hsa052150.25374994
118p53 signaling pathway_Homo sapiens_hsa041150.23266763
119Legionellosis_Homo sapiens_hsa051340.22377516
120Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.22333433
121Colorectal cancer_Homo sapiens_hsa052100.19786989
122Cell cycle_Homo sapiens_hsa041100.19766366
123Homologous recombination_Homo sapiens_hsa034400.18700886
124Thyroid cancer_Homo sapiens_hsa052160.17431853
125Glycerophospholipid metabolism_Homo sapiens_hsa005640.16404771
126Endometrial cancer_Homo sapiens_hsa052130.16193654
127Linoleic acid metabolism_Homo sapiens_hsa005910.15196059
128Glycerolipid metabolism_Homo sapiens_hsa005610.13534131
129Galactose metabolism_Homo sapiens_hsa000520.10968180
130Renal cell carcinoma_Homo sapiens_hsa052110.10068584
131Pentose phosphate pathway_Homo sapiens_hsa000300.09724057
132HIF-1 signaling pathway_Homo sapiens_hsa040660.08570376
133mRNA surveillance pathway_Homo sapiens_hsa030150.07784311
134Protein digestion and absorption_Homo sapiens_hsa049740.05962984
135Ether lipid metabolism_Homo sapiens_hsa005650.05609249
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.05399530
137Caffeine metabolism_Homo sapiens_hsa002320.05326322
138Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.05271995

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