CPXM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)5.53137427
2protein heterotrimerization (GO:0070208)5.51055460
3keratan sulfate catabolic process (GO:0042340)5.21849643
4bone trabecula formation (GO:0060346)4.68175318
5extracellular matrix assembly (GO:0085029)4.52960258
6desmosome organization (GO:0002934)4.43643507
7collagen metabolic process (GO:0032963)4.38060147
8peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.31683571
9collagen catabolic process (GO:0030574)4.29152673
10multicellular organismal macromolecule metabolic process (GO:0044259)4.12054647
11skin morphogenesis (GO:0043589)4.10260778
12myoblast migration (GO:0051451)4.06933756
13cell migration involved in heart development (GO:0060973)4.06367560
14blood vessel maturation (GO:0001955)4.03384141
15multicellular organismal catabolic process (GO:0044243)3.95855762
16smooth muscle tissue development (GO:0048745)3.94181095
17multicellular organismal metabolic process (GO:0044236)3.90477204
18epithelial cell-cell adhesion (GO:0090136)3.90238019
19planar cell polarity pathway involved in neural tube closure (GO:0090179)3.79499565
20dermatan sulfate biosynthetic process (GO:0030208)3.78831575
21glomerular filtration (GO:0003094)3.75383934
22cardiac myofibril assembly (GO:0055003)3.71503466
23endothelial cell morphogenesis (GO:0001886)3.64686564
24dermatan sulfate metabolic process (GO:0030205)3.62918131
25hemidesmosome assembly (GO:0031581)3.57935106
26extracellular matrix disassembly (GO:0022617)3.50957470
27vascular endothelial growth factor signaling pathway (GO:0038084)3.50846759
28regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.46320008
29cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.43685189
30fibril organization (GO:0097435)3.36636714
31myofibril assembly (GO:0030239)3.35108665
32renal filtration (GO:0097205)3.32771132
33endodermal cell differentiation (GO:0035987)3.31443214
34adhesion of symbiont to host (GO:0044406)3.31171402
35cell proliferation involved in metanephros development (GO:0072203)3.30212443
36sarcomere organization (GO:0045214)3.24634845
37muscle cell migration (GO:0014812)3.24572680
38negative regulation of leukocyte chemotaxis (GO:0002689)3.24372216
39sequestering of extracellular ligand from receptor (GO:0035581)3.23509930
40non-canonical Wnt signaling pathway (GO:0035567)3.17674687
41trabecula formation (GO:0060343)3.15711292
42cell adhesion mediated by integrin (GO:0033627)3.13165230
43plasma membrane repair (GO:0001778)3.09524427
44negative regulation of smooth muscle cell migration (GO:0014912)2.98637305
45peptidyl-proline hydroxylation (GO:0019511)2.97567912
46negative regulation of embryonic development (GO:0045992)2.97102240
47vasculature development (GO:0001944)2.97045921
48cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.95684338
49negative regulation of chondrocyte differentiation (GO:0032331)2.94624127
50endocardial cushion morphogenesis (GO:0003203)2.93575520
51negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.93386999
52regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.93264130
53cell migration involved in sprouting angiogenesis (GO:0002042)2.92609889
54bundle of His cell to Purkinje myocyte communication (GO:0086069)2.91397203
55lymphangiogenesis (GO:0001946)2.91182913
56regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.89795088
57regulation of heart morphogenesis (GO:2000826)2.89544381
58lung vasculature development (GO:0060426)2.88437711
59cellular response to interferon-alpha (GO:0035457)2.88422089
60cardiac muscle cell proliferation (GO:0060038)2.88289939
61glycoprotein catabolic process (GO:0006516)2.88104573
62regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.88036642
63auditory receptor cell differentiation (GO:0042491)2.87111889
64chondrocyte proliferation (GO:0035988)2.86913417
65regulation of cardioblast differentiation (GO:0051890)2.86884901
66adhesion of symbiont to host cell (GO:0044650)2.86546473
67virion attachment to host cell (GO:0019062)2.86546473
68ventricular septum development (GO:0003281)2.86071854
69protein hydroxylation (GO:0018126)2.85121598
70extracellular fibril organization (GO:0043206)2.84097605
71mesenchyme morphogenesis (GO:0072132)2.81693783
72skeletal muscle adaptation (GO:0043501)2.81073270
73cartilage condensation (GO:0001502)2.80001185
74cell aggregation (GO:0098743)2.80001185
75extracellular matrix organization (GO:0030198)2.78632922
76regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.78554974
77keratinocyte proliferation (GO:0043616)2.78105748
78regulation of transforming growth factor beta2 production (GO:0032909)2.77642326
79extracellular structure organization (GO:0043062)2.77388949
80tooth mineralization (GO:0034505)2.77048733
81pathway-restricted SMAD protein phosphorylation (GO:0060389)2.76117919
82metanephric mesenchyme development (GO:0072075)2.76051313
83negative regulation of catenin import into nucleus (GO:0035414)2.75882278
84regulation of plasminogen activation (GO:0010755)2.75611633
85muscle filament sliding (GO:0030049)2.74066639
86actin-myosin filament sliding (GO:0033275)2.74066639
87negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.73893768
88vitamin A metabolic process (GO:0006776)2.72330994
89peripheral nervous system axon ensheathment (GO:0032292)2.71172143
90myelination in peripheral nervous system (GO:0022011)2.71172143
91neuron projection extension involved in neuron projection guidance (GO:1902284)2.70884039
92axon extension involved in axon guidance (GO:0048846)2.70884039
93negative regulation of protein localization to cell surface (GO:2000009)2.70881604
94adrenal gland development (GO:0030325)2.70546974
95positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.69970057
96response to BMP (GO:0071772)2.69216452
97cellular response to BMP stimulus (GO:0071773)2.69216452
98type B pancreatic cell proliferation (GO:0044342)2.67696759
99head development (GO:0060322)2.66447907
100glomerular visceral epithelial cell development (GO:0072015)2.65740728
101negative regulation of BMP signaling pathway (GO:0030514)2.65634564
102heart trabecula formation (GO:0060347)2.65179861
103cell proliferation involved in kidney development (GO:0072111)2.64700025
104positive regulation of mesenchymal cell proliferation (GO:0002053)2.63971959
105negative regulation of cell fate specification (GO:0009996)2.63355690
106endocrine hormone secretion (GO:0060986)2.62720632
107cellular response to vitamin (GO:0071295)2.62386917
108regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.61617322
109outer ear morphogenesis (GO:0042473)2.61593427
110regulation of skeletal muscle contraction (GO:0014819)2.61406877
111Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.60859664
112extracellular regulation of signal transduction (GO:1900115)2.60200263
113extracellular negative regulation of signal transduction (GO:1900116)2.60200263
114regulation of secondary heart field cardioblast proliferation (GO:0003266)2.59885938
115regulation of cardioblast proliferation (GO:0003264)2.59885938
116cardiac cell development (GO:0055006)2.59879960
117cochlea morphogenesis (GO:0090103)2.58667636
118chondroitin sulfate catabolic process (GO:0030207)2.58540218
119artery morphogenesis (GO:0048844)2.58517711
120cornea development in camera-type eye (GO:0061303)2.56706114
121mesenchymal-epithelial cell signaling (GO:0060638)2.56272608
122heart valve morphogenesis (GO:0003179)2.55385271
123cardiac muscle cell development (GO:0055013)2.54241246
124negative regulation of potassium ion transmembrane transport (GO:1901380)2.54141259
125retinal metabolic process (GO:0042574)2.53931536
126aorta morphogenesis (GO:0035909)2.53846281
127auditory behavior (GO:0031223)2.53757462
128positive regulation of endothelial cell apoptotic process (GO:2000353)2.53252038
129cellular response to vitamin D (GO:0071305)2.53061370
130atrioventricular valve morphogenesis (GO:0003181)2.52840256
131positive regulation of osteoblast proliferation (GO:0033690)2.51722510
132embryonic cranial skeleton morphogenesis (GO:0048701)2.51635328
133glycosaminoglycan catabolic process (GO:0006027)2.51527968
134retina vasculature morphogenesis in camera-type eye (GO:0061299)2.51165103
135actin-mediated cell contraction (GO:0070252)2.50543475
136negative regulation of striated muscle cell apoptotic process (GO:0010664)2.50185607
137gland morphogenesis (GO:0022612)2.49636132
138negative regulation of axon extension involved in axon guidance (GO:0048843)2.49339931
139actomyosin structure organization (GO:0031032)2.49262114
140negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.48591190
141negative regulation of cartilage development (GO:0061037)2.48567536
142face morphogenesis (GO:0060325)2.47956418
143regulation of integrin-mediated signaling pathway (GO:2001044)2.47680415
144cardiac epithelial to mesenchymal transition (GO:0060317)2.47626137
145glomerular basement membrane development (GO:0032836)2.47061786
146regulation of organ formation (GO:0003156)2.46905317
147kidney mesenchyme development (GO:0072074)2.46573331
148negative regulation of osteoblast proliferation (GO:0033689)2.46441245
149middle ear morphogenesis (GO:0042474)2.46404468
150convergent extension (GO:0060026)2.43402881
151pattern specification involved in kidney development (GO:0061004)2.42654592
152branching involved in salivary gland morphogenesis (GO:0060445)2.42581747
153endocardial cushion development (GO:0003197)2.40364434
154barbed-end actin filament capping (GO:0051016)2.40101180
155regulation of mesenchymal cell proliferation (GO:0010464)2.37978497
156negative chemotaxis (GO:0050919)2.36808733
157basement membrane organization (GO:0071711)2.36371644
158glomerular epithelial cell development (GO:0072310)2.36021212
159vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.36005142
160chondrocyte development (GO:0002063)2.35469051
161positive regulation of smoothened signaling pathway (GO:0045880)2.33041641

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.13726218
2TRIM28_21343339_ChIP-Seq_HEK293_Human5.74955445
3PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.89183378
4RARG_19884340_ChIP-ChIP_MEFs_Mouse2.80834272
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.50116279
6GBX2_23144817_ChIP-Seq_PC3_Human2.45925201
7EP300_21415370_ChIP-Seq_HL-1_Mouse2.41023434
8TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.38221629
9ESR1_21235772_ChIP-Seq_MCF-7_Human2.35289233
10* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.18994142
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.12778538
12TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.05960272
13CLOCK_20551151_ChIP-Seq_293T_Human2.04455741
14CJUN_26792858_Chip-Seq_BT549_Human1.98555960
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.91785886
16SMAD_19615063_ChIP-ChIP_OVARY_Human1.85470688
17TP53_16413492_ChIP-PET_HCT116_Human1.85073001
18RNF2_18974828_ChIP-Seq_MESCs_Mouse1.84878723
19EZH2_18974828_ChIP-Seq_MESCs_Mouse1.84878723
20SOX9_24532713_ChIP-Seq_HFSC_Mouse1.83899251
21EED_16625203_ChIP-ChIP_MESCs_Mouse1.80618260
22CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.79786248
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.79296555
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.70930761
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70822969
26SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.66589156
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.66412874
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58440601
29EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56202058
30* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.55955859
31RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.55861145
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.55121444
33* TBX20_22080862_ChIP-Seq_HEART_Mouse1.54444623
34* TBX20_22328084_ChIP-Seq_HEART_Mouse1.54444623
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54168147
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.51793062
37WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.47254960
38JARID2_20075857_ChIP-Seq_MESCs_Mouse1.46839401
39WT1_19549856_ChIP-ChIP_CCG9911_Human1.44852509
40PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.44147712
41SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.43806443
42CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.43248112
43FOXO3_23340844_ChIP-Seq_DLD1_Human1.41957288
44TP53_20018659_ChIP-ChIP_R1E_Mouse1.41629848
45SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.41072108
46EZH2_27304074_Chip-Seq_ESCs_Mouse1.40927530
47JARID2_20064375_ChIP-Seq_MESCs_Mouse1.36457390
48NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.35909914
49EZH2_22144423_ChIP-Seq_EOC_Human1.35365686
50CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.34576074
51BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.33933603
52MTF2_20144788_ChIP-Seq_MESCs_Mouse1.29844880
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29479344
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29351153
55AR_21572438_ChIP-Seq_LNCaP_Human1.29192055
56NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.28195134
57NRF2_20460467_ChIP-Seq_MEFs_Mouse1.28195134
58P63_26484246_Chip-Seq_KERATINOCYTES_Human1.27375709
59PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27366644
60RNF2_27304074_Chip-Seq_ESCs_Mouse1.26743612
61PPAR_26484153_Chip-Seq_NCI-H1993_Human1.25721952
62TP53_18474530_ChIP-ChIP_U2OS_Human1.23459073
63EZH2_27294783_Chip-Seq_ESCs_Mouse1.22018099
64SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.21232725
65GATA2_21666600_ChIP-Seq_HMVEC_Human1.19252866
66STAT6_21828071_ChIP-Seq_BEAS2B_Human1.18409082
67HIF1A_21447827_ChIP-Seq_MCF-7_Human1.18063030
68ZNF263_19887448_ChIP-Seq_K562_Human1.17357817
69SUZ12_27294783_Chip-Seq_ESCs_Mouse1.16547418
70MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15852481
71SMAD4_21799915_ChIP-Seq_A2780_Human1.14460220
72NFIB_24661679_ChIP-Seq_LUNG_Mouse1.13462776
73SOX2_20726797_ChIP-Seq_SW620_Human1.12968853
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12452900
75RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.11524474
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.11484884
77SMC1_22415368_ChIP-Seq_MEFs_Mouse1.11225373
78* AHR_22903824_ChIP-Seq_MCF-7_Human1.10778720
79* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.10774760
80NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10183606
81ISL1_27105846_Chip-Seq_CPCs_Mouse1.09759737
82JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08679472
83BRD4_25478319_ChIP-Seq_HGPS_Human1.08048512
84P300_19829295_ChIP-Seq_ESCs_Human1.07684481
85SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06226857
86RUNX1_27514584_Chip-Seq_MCF-7_Human1.05350246
87* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04545199
88SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.03931692
89SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.03931692
90UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02462402
91CBX2_27304074_Chip-Seq_ESCs_Mouse1.00855728
92PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00005475
93JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99685628
94* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99370204
95CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98727704
96UBF1/2_26484160_Chip-Seq_HMECs_Human0.98661336
97RACK7_27058665_Chip-Seq_MCF-7_Human0.98336762
98SA1_22415368_ChIP-Seq_MEFs_Mouse0.98271022
99KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.98233260
100RING1B_27294783_Chip-Seq_ESCs_Mouse0.98086680
101DROSHA_22980978_ChIP-Seq_HELA_Human0.97896132
102SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97702754
103* ARNT_22903824_ChIP-Seq_MCF-7_Human0.97381103
104SMAD3_21741376_ChIP-Seq_EPCs_Human0.96292265
105OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95726439
106P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95223899
107THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.94215729
108AR_25329375_ChIP-Seq_VCAP_Human0.93089005
109TP63_23658742_ChIP-Seq_EP156T_Human0.92549426
110KDM2B_26808549_Chip-Seq_K562_Human0.92516774
111TBX3_20139965_ChIP-Seq_MESCs_Mouse0.92409782
112* TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.92300498
113TBX3_20139965_ChIP-Seq_ESCs_Mouse0.91969897
114KLF5_25053715_ChIP-Seq_YYC3_Human0.91856518
115TCF4_18268006_ChIP-ChIP_LS174T_Human0.91744940
116NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.91625133
117NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91565259
118* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91500666
119KDM2B_26808549_Chip-Seq_REH_Human0.91181532
120TP53_23651856_ChIP-Seq_MEFs_Mouse0.90058864
121BCAT_22108803_ChIP-Seq_LS180_Human0.89084023
122GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88666078
123CTBP2_25329375_ChIP-Seq_LNCAP_Human0.88125114
124ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.87878626
125KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.85048492
126KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.85048492
127KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.85048492
128ATF3_27146783_Chip-Seq_COLON_Human0.83391913
129ERG_21242973_ChIP-ChIP_JURKAT_Human0.82412193
130SMC3_22415368_ChIP-Seq_MEFs_Mouse0.82074566
131RXR_22108803_ChIP-Seq_LS180_Human0.81961336
132KDM2B_26808549_Chip-Seq_SUP-B15_Human0.81676482
133TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81136059
134ELK3_25401928_ChIP-Seq_HUVEC_Human0.80880025
135SMAD3_21741376_ChIP-Seq_HESCs_Human0.80858079
136CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.80366339

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.52028195
2MP0005275_abnormal_skin_tensile5.84529108
3MP0005503_abnormal_tendon_morphology5.71707227
4MP0005257_abnormal_intraocular_pressure3.17371459
5MP0003705_abnormal_hypodermis_morpholog3.08195567
6MP0002837_dystrophic_cardiac_calcinosis2.81565287
7MP0010368_abnormal_lymphatic_system2.74073145
8MP0000751_myopathy2.70379482
9MP0003279_aneurysm2.67958298
10MP0001958_emphysema2.67832077
11MP0003136_yellow_coat_color2.58362794
12MP0003879_abnormal_hair_cell2.41036059
13MP0005508_abnormal_skeleton_morphology2.33289707
14MP0003941_abnormal_skin_development2.29161538
15MP0009384_cardiac_valve_regurgitation2.27528212
16MP0002060_abnormal_skin_morphology2.26121791
17MP0006054_spinal_hemorrhage2.20558724
18MP0004272_abnormal_basement_membrane2.19855780
19MP0002108_abnormal_muscle_morphology2.00856201
20MP0004084_abnormal_cardiac_muscle1.80429467
21MP0001879_abnormal_lymphatic_vessel1.72997562
22MP0005377_hearing/vestibular/ear_phenot1.67835646
23MP0003878_abnormal_ear_physiology1.67835646
24MP0003646_muscle_fatigue1.65054300
25MP0005595_abnormal_vascular_smooth1.60228965
26MP0009250_abnormal_appendicular_skeleto1.55631563
27MP0002295_abnormal_pulmonary_circulatio1.51286720
28MP0004858_abnormal_nervous_system1.48158074
29MP0003566_abnormal_cell_adhesion1.45553852
30MP0001485_abnormal_pinna_reflex1.42489758
31MP0002796_impaired_skin_barrier1.41669665
32MP0000750_abnormal_muscle_regeneration1.39587498
33MP0003950_abnormal_plasma_membrane1.36707481
34MP0005330_cardiomyopathy1.36574368
35MP0004036_abnormal_muscle_relaxation1.35206374
36MP0010030_abnormal_orbit_morphology1.34248195
37MP0002933_joint_inflammation1.34119422
38MP0005623_abnormal_meninges_morphology1.33297522
39MP0004087_abnormal_muscle_fiber1.32105210
40MP0004215_abnormal_myocardial_fiber1.29103387
41MP0000762_abnormal_tongue_morphology1.24714852
42MP0000383_abnormal_hair_follicle1.24089761
43MP0005023_abnormal_wound_healing1.23091980
44MP0005390_skeleton_phenotype1.21981306
45MP0003385_abnormal_body_wall1.20508237
46MP0010234_abnormal_vibrissa_follicle1.20468170
47MP0000749_muscle_degeneration1.19120024
48MP0003091_abnormal_cell_migration1.14713180
49MP0000163_abnormal_cartilage_morphology1.13684284
50MP0005369_muscle_phenotype1.13204847
51MP0001542_abnormal_bone_strength1.10858602
52MP0004484_altered_response_of1.10326242
53MP0002254_reproductive_system_inflammat1.09870794
54MP0010678_abnormal_skin_adnexa1.09838485
55MP0004134_abnormal_chest_morphology1.09694177
56MP0002282_abnormal_trachea_morphology1.08919126
57MP0010386_abnormal_urinary_bladder1.08085440
58MP0000026_abnormal_inner_ear1.06995776
59MP0002896_abnormal_bone_mineralization1.06391935
60MP0002972_abnormal_cardiac_muscle1.06074587
61MP0002249_abnormal_larynx_morphology1.04370342
62MP0000579_abnormal_nail_morphology1.04123058
63MP0002115_abnormal_skeleton_extremities1.03913425
64MP0000566_synostosis1.03670914
65MP0001346_abnormal_lacrimal_gland1.03477539
66MP0001299_abnormal_eye_distance/1.01874498
67MP0000534_abnormal_ureter_morphology1.01795820
68MP0003942_abnormal_urinary_system0.98645850
69MP0002932_abnormal_joint_morphology0.97854588
70MP0003828_pulmonary_edema0.96813130
71MP0005248_abnormal_Harderian_gland0.96415477
72MP0010352_gastrointestinal_tract_polyps0.96345776
73MP0005620_abnormal_muscle_contractility0.95877116
74MP0000759_abnormal_skeletal_muscle0.95374346
75MP0000733_abnormal_muscle_development0.95001860
76MP0010630_abnormal_cardiac_muscle0.94818412
77MP0008775_abnormal_heart_ventricle0.93791698
78MP0000767_abnormal_smooth_muscle0.93294212
79MP0002009_preneoplasia0.92625549
80MP0002106_abnormal_muscle_physiology0.91473597
81MP0001243_abnormal_dermal_layer0.91375556
82MP0001544_abnormal_cardiovascular_syste0.91366494
83MP0005385_cardiovascular_system_phenoty0.91366494
84MP0000747_muscle_weakness0.90838487
85MP0010771_integument_phenotype0.89874020
86MP0009053_abnormal_anal_canal0.89470807
87MP0005388_respiratory_system_phenotype0.88923655
88MP0002133_abnormal_respiratory_system0.88923655
89MP0000049_abnormal_middle_ear0.88912384
90MP0000428_abnormal_craniofacial_morphol0.87237755
91MP0005171_absent_coat_pigmentation0.87008465
92MP0004145_abnormal_muscle_electrophysio0.86695408
93MP0001963_abnormal_hearing_physiology0.83803654
94MP0000467_abnormal_esophagus_morphology0.83493504
95MP0003453_abnormal_keratinocyte_physiol0.83197547
96MP0004185_abnormal_adipocyte_glucose0.82904933
97MP0002233_abnormal_nose_morphology0.82455048
98MP0000432_abnormal_head_morphology0.79722462
99MP0000537_abnormal_urethra_morphology0.76800341
100MP0002653_abnormal_ependyma_morphology0.76780650
101MP0006138_congestive_heart_failure0.76541956
102MP0001849_ear_inflammation0.75895487
103MP0002128_abnormal_blood_circulation0.75763070
104MP0005501_abnormal_skin_physiology0.74524831
105MP0003011_delayed_dark_adaptation0.74418328
106MP0003283_abnormal_digestive_organ0.73924706
107MP0003045_fibrosis0.73419743
108MP0003755_abnormal_palate_morphology0.73286071
109MP0000013_abnormal_adipose_tissue0.72869448
110MP0004885_abnormal_endolymph0.71790172
111MP0002113_abnormal_skeleton_development0.71423820
112MP0002234_abnormal_pharynx_morphology0.70447622
113MP0005164_abnormal_response_to0.69687830
114MP0009780_abnormal_chondrocyte_physiolo0.69215605
115MP0001614_abnormal_blood_vessel0.68982585
116MP0001270_distended_abdomen0.68867784
117MP0002109_abnormal_limb_morphology0.68221228
118MP0000230_abnormal_systemic_arterial0.65143090
119MP0002116_abnormal_craniofacial_bone0.64134379
120MP0000003_abnormal_adipose_tissue0.63447990
121MP0005670_abnormal_white_adipose0.63198611
122MP0002998_abnormal_bone_remodeling0.62019215
123MP0003935_abnormal_craniofacial_develop0.61454244
124MP0002168_other_aberrant_phenotype0.59863334
125MP0002127_abnormal_cardiovascular_syste0.58903716
126MP0005197_abnormal_uvea_morphology0.54993645
127MP0000343_altered_response_to0.54565977
128MP0000249_abnormal_blood_vessel0.53440609
129MP0000538_abnormal_urinary_bladder0.52017921
130MP0003115_abnormal_respiratory_system0.49179280
131MP0002925_abnormal_cardiovascular_devel0.48036148
132MP0005165_increased_susceptibility_to0.47862037
133MP0003937_abnormal_limbs/digits/tail_de0.47297643
134MP0003795_abnormal_bone_structure0.46614561
135MP0001175_abnormal_lung_morphology0.45511658

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.31122148
2Premature rupture of membranes (HP:0001788)6.84032414
3Aortic dissection (HP:0002647)4.93270397
4Atrophic scars (HP:0001075)4.45163523
5Ankle contracture (HP:0006466)4.32812818
6Broad metatarsal (HP:0001783)4.28937352
7Aortic aneurysm (HP:0004942)4.14998987
8Soft skin (HP:0000977)3.96230798
9Shallow orbits (HP:0000586)3.90401607
10Epiphyseal dysplasia (HP:0002656)3.90206122
11Hypoplastic ischia (HP:0003175)3.83025729
12Increased connective tissue (HP:0009025)3.78678791
13Type 1 muscle fiber predominance (HP:0003803)3.76499426
14Bladder diverticulum (HP:0000015)3.69196828
15Right ventricular cardiomyopathy (HP:0011663)3.55012182
16Fragile skin (HP:0001030)3.52203891
17Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.50618615
18Muscle fiber splitting (HP:0003555)3.40052925
19Peritonitis (HP:0002586)3.39738444
20Abnormality of the ischium (HP:0003174)3.38573864
21Vascular tortuosity (HP:0004948)3.37684468
22Abnormality of dentin (HP:0010299)3.35112299
23Neonatal short-limb short stature (HP:0008921)3.22347354
24Mild short stature (HP:0003502)3.15728673
25Cerebral aneurysm (HP:0004944)3.12018319
26Hyporeflexia of lower limbs (HP:0002600)3.07662794
27Dilatation of the ascending aorta (HP:0005111)3.05043303
28Follicular hyperkeratosis (HP:0007502)3.04274853
29Wormian bones (HP:0002645)3.01849988
30Ventricular tachycardia (HP:0004756)3.00469357
31Mitral valve prolapse (HP:0001634)2.95396830
32Osteoarthritis (HP:0002758)2.90902872
33Aortic regurgitation (HP:0001659)2.86804775
34Severe Myopia (HP:0011003)2.85100229
35Spinal rigidity (HP:0003306)2.83840389
36Aortic valve stenosis (HP:0001650)2.82725484
37Increased variability in muscle fiber diameter (HP:0003557)2.82550808
38Sudden death (HP:0001699)2.78498542
39Coronal craniosynostosis (HP:0004440)2.72047378
40Blue sclerae (HP:0000592)2.69400540
41Osteolytic defects of the hand bones (HP:0009699)2.68767481
42Osteolytic defects of the phalanges of the hand (HP:0009771)2.68767481
43Genu recurvatum (HP:0002816)2.68513933
44Hyperextensible skin (HP:0000974)2.67663430
45Calf muscle hypertrophy (HP:0008981)2.66975600
46Arterial tortuosity (HP:0005116)2.65993998
47Broad ribs (HP:0000885)2.65429042
48Bell-shaped thorax (HP:0001591)2.63221778
49Round ear (HP:0100830)2.60975379
50Abnormality of the calf musculature (HP:0001430)2.58647219
51Morphological abnormality of the middle ear (HP:0008609)2.57954318
52Cervical subluxation (HP:0003308)2.53061233
53Vertebral compression fractures (HP:0002953)2.51669334
54Joint stiffness (HP:0001387)2.51097083
55Mildly elevated creatine phosphokinase (HP:0008180)2.50220028
56Exercise-induced myalgia (HP:0003738)2.47793754
57Abnormality of skeletal muscle fiber size (HP:0012084)2.43773404
58Keratoconus (HP:0000563)2.43560419
59Increased corneal curvature (HP:0100692)2.43560419
60Wrist flexion contracture (HP:0001239)2.41650672
61Aneurysm (HP:0002617)2.41587843
62Muscle hypertrophy of the lower extremities (HP:0008968)2.40225233
63Exercise-induced muscle cramps (HP:0003710)2.33809377
64Biconcave vertebral bodies (HP:0004586)2.31047380
65Persistence of primary teeth (HP:0006335)2.31034958
66Flat cornea (HP:0007720)2.30476419
67Absent frontal sinuses (HP:0002688)2.29286195
68Bronchomalacia (HP:0002780)2.27007693
69Vitreoretinal degeneration (HP:0000655)2.26852003
70Hypoventilation (HP:0002791)2.24698973
71Slender build (HP:0001533)2.23938886
72Lipoatrophy (HP:0100578)2.23606820
73Abnormal delivery (HP:0001787)2.22013764
74Elbow flexion contracture (HP:0002987)2.21573388
75Overgrowth (HP:0001548)2.21328820
76Lip pit (HP:0100267)2.20348680
77Spondylolisthesis (HP:0003302)2.20272692
78Bowel diverticulosis (HP:0005222)2.17778262
79Ectopia lentis (HP:0001083)2.15708819
80Wide anterior fontanel (HP:0000260)2.12537523
81Ovoid vertebral bodies (HP:0003300)2.11962037
82Striae distensae (HP:0001065)2.11795838
83Alopecia of scalp (HP:0002293)2.10279825
84Platyspondyly (HP:0000926)2.07142631
85Mitral regurgitation (HP:0001653)2.06577243
86Pulmonary artery stenosis (HP:0004415)2.06051769
87Mitral stenosis (HP:0001718)2.04791487
88Atrial fibrillation (HP:0005110)2.04241131
89Rectal prolapse (HP:0002035)2.00608672
90Joint laxity (HP:0001388)1.99991704
91Abnormality of the pubic bones (HP:0003172)1.98307324
92Short hallux (HP:0010109)1.97150451
93Aplasia involving bones of the upper limbs (HP:0009823)1.95069242
94Aplasia of the phalanges of the hand (HP:0009802)1.95069242
95Aplasia involving bones of the extremities (HP:0009825)1.95069242
96Synostosis involving bones of the feet (HP:0009140)1.94176232
97Synostosis involving bones of the lower limbs (HP:0009138)1.94176232
98Camptodactyly of toe (HP:0001836)1.92334322
99Narrow nasal bridge (HP:0000446)1.91621699
100Infantile muscular hypotonia (HP:0008947)1.91163167
101Venous abnormality (HP:0002624)1.90760470
102Gingival overgrowth (HP:0000212)1.87824738
103Distal lower limb muscle weakness (HP:0009053)1.87804027
104Primary atrial arrhythmia (HP:0001692)1.87014156
105Hypoplasia of the odontoid process (HP:0003311)1.86725291
106Hypoplasia of the iris (HP:0007676)1.86156106
107Delayed closure of the anterior fontanelle (HP:0001476)1.84461764
108Bradycardia (HP:0001662)1.84010611
109Systemic lupus erythematosus (HP:0002725)1.83343374
110Abnormality of complement system (HP:0005339)1.82611551
111Knee flexion contracture (HP:0006380)1.82156758
112Hip contracture (HP:0003273)1.81950153
113Nonimmune hydrops fetalis (HP:0001790)1.81285665
114Mixed hearing impairment (HP:0000410)1.80993165
115Turricephaly (HP:0000262)1.80700801
116Abnormality of the acetabulum (HP:0003170)1.79967947
117Deviation of the hallux (HP:0010051)1.79418544
118Aplasia/Hypoplasia of the hallux (HP:0008362)1.78201271
119Irregular epiphyses (HP:0010582)1.77409036
120Venous insufficiency (HP:0005293)1.75912507
121Supraventricular arrhythmia (HP:0005115)1.75430111
122Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.74908004
123Tarsal synostosis (HP:0008368)1.74131758
124Limited hip movement (HP:0008800)1.73617072
125Supraventricular tachycardia (HP:0004755)1.73439382
126Delayed cranial suture closure (HP:0000270)1.72616806
127Hallux valgus (HP:0001822)1.72318983
128Pterygium (HP:0001059)1.70560151
129Emphysema (HP:0002097)1.69970732
130Flared iliac wings (HP:0002869)1.69280691
131Protruding ear (HP:0000411)1.68482952
132Abnormality of the anterior chamber (HP:0000593)1.67750107
133Short nail (HP:0001799)1.67680199
134Inguinal hernia (HP:0000023)1.66250418
135White forelock (HP:0002211)1.63193664
136Abnormality of skull ossification (HP:0002703)1.62810169
137Coxa vara (HP:0002812)1.62331066
138Natal tooth (HP:0000695)1.61466679
139Femoral bowing (HP:0002980)1.61191319
140Generalized amyotrophy (HP:0003700)1.59695948

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR26.16233638
2TTN4.23036866
3LATS13.90410473
4TRIB33.23347432
5PNCK3.05233511
6EPHA32.91528534
7LATS22.68481406
8MYLK2.56437688
9PDGFRA2.50945713
10LMTK22.29829532
11DMPK2.25756698
12GRK12.25142770
13PKN22.23668265
14TRPM72.12401708
15FER1.99128841
16MAPKAPK31.97614960
17ERN11.84686204
18PHKG21.77764193
19PHKG11.77764193
20EPHB21.73632414
21RIPK11.69943860
22TESK11.61819680
23MAP3K61.56085651
24ADRBK21.54770909
25SIK11.48936581
26STK38L1.41244995
27KIT1.40046330
28EPHB11.39988333
29MST1R1.39891817
30PAK31.38404806
31MAP3K31.32425744
32CASK1.31587546
33OBSCN1.29997105
34PRKD31.25530785
35TGFBR21.24599353
36PDK21.24300617
37MET1.20108488
38MAPK71.17486065
39PDK31.16047153
40PDK41.16047153
41PTK61.15380937
42LRRK21.11727282
43MOS1.07900883
44PIK3CA1.07337451
45EEF2K1.02990550
46PAK21.02477503
47IRAK11.02173853
48STK391.02040929
49TGFBR11.00787508
50BMPR1B0.99818939
51STK30.99226736
52ABL20.98268083
53FGFR40.95343104
54ILK0.93538695
55WEE10.93048206
56GRK50.90847561
57ROCK10.89183663
58STK240.87847930
59MAP3K70.83024504
60PRKD10.82680706
61FGFR30.82358766
62PDGFRB0.81579102
63FRK0.80676408
64MAP3K20.80402779
65ROCK20.80097125
66FGFR20.74175272
67MAPK150.71161390
68ERBB30.70906929
69PIK3CG0.69533991
70MAPKAPK50.67842523
71RET0.66847686
72PRKCH0.66263532
73FGFR10.66253300
74BCKDK0.62675429
75NTRK10.62442503
76PTK20.61058022
77CDC42BPA0.60762264
78RPS6KA20.58420809
79TAOK10.55573061
80MAP2K10.54063741
81NTRK20.53234624
82PKN10.52030999
83JAK10.51261390
84DYRK1B0.49563677
85PRKG20.49245264
86PRKD20.47207861
87PRKCE0.45474542
88STK380.44573519
89SGK4940.44238757
90SGK2230.44238757
91TIE10.43321349
92TSSK60.43319708
93CAMK10.42684429
94KSR20.42241392
95RPS6KB20.41951488
96AKT30.41830677
97DAPK30.41789636
98EPHA20.40230422
99BMX0.40048425
100CAMK2G0.40033824
101JAK20.39162950
102MAPK120.38669492
103WNK10.38139373
104PRKAA20.38043820
105MTOR0.37637396
106PAK40.37445449
107WNK40.36718579
108PTK2B0.35758568
109ARAF0.35673197
110PRKG10.35073402
111NLK0.34770710
112FLT30.34684799
113CDK60.33869432
114NEK90.33312313
115SGK20.32363810
116ERBB20.32078881
117NUAK10.31943420
118MUSK0.31455885
119CAMK2D0.31285251
120MAPK40.30979296
121ABL10.28809964
122PLK20.28626889
123PINK10.28430659
124RPS6KC10.28344965
125RPS6KL10.28344965
126GSK3A0.28012967
127LIMK10.27674222
128TYRO30.27484827
129INSR0.27454992
130SRC0.27140276
131IGF1R0.27081256
132ADRBK10.26915642
133PIM20.26064559
134MAP3K10.25812029
135HIPK20.23638496

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.55490878
2Protein digestion and absorption_Homo sapiens_hsa049743.03664879
3Focal adhesion_Homo sapiens_hsa045102.81746820
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.72506647
5Dilated cardiomyopathy_Homo sapiens_hsa054142.71781195
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.59703107
7Glycosaminoglycan degradation_Homo sapiens_hsa005312.39213548
8Basal cell carcinoma_Homo sapiens_hsa052172.10210058
9Amoebiasis_Homo sapiens_hsa051461.93267924
10Hippo signaling pathway_Homo sapiens_hsa043901.88157813
11Proteoglycans in cancer_Homo sapiens_hsa052051.76074296
12Caffeine metabolism_Homo sapiens_hsa002321.71439319
13TGF-beta signaling pathway_Homo sapiens_hsa043501.70246869
14Malaria_Homo sapiens_hsa051441.69643058
15AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.66645181
16Complement and coagulation cascades_Homo sapiens_hsa046101.64694339
17Adherens junction_Homo sapiens_hsa045201.58614535
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.52380374
19Hedgehog signaling pathway_Homo sapiens_hsa043401.35417431
20PI3K-Akt signaling pathway_Homo sapiens_hsa041511.33226042
21Fatty acid degradation_Homo sapiens_hsa000711.30483321
22Wnt signaling pathway_Homo sapiens_hsa043101.29086879
23Tight junction_Homo sapiens_hsa045301.27685100
24Cardiac muscle contraction_Homo sapiens_hsa042601.25349140
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.22729869
26Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.19198997
27Melanogenesis_Homo sapiens_hsa049161.18906910
28Bladder cancer_Homo sapiens_hsa052191.15945114
29Primary bile acid biosynthesis_Homo sapiens_hsa001201.15759924
30Small cell lung cancer_Homo sapiens_hsa052221.14283472
31Insulin resistance_Homo sapiens_hsa049311.12720243
32ABC transporters_Homo sapiens_hsa020101.07012924
33Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.05082539
34Phototransduction_Homo sapiens_hsa047441.03453599
35Melanoma_Homo sapiens_hsa052181.03273177
36Vascular smooth muscle contraction_Homo sapiens_hsa042701.01686177
37Lysosome_Homo sapiens_hsa041421.01428397
38Leukocyte transendothelial migration_Homo sapiens_hsa046700.99391430
39Regulation of actin cytoskeleton_Homo sapiens_hsa048100.97606826
40Viral myocarditis_Homo sapiens_hsa054160.97302768
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96126531
42Cyanoamino acid metabolism_Homo sapiens_hsa004600.95502669
43Ovarian steroidogenesis_Homo sapiens_hsa049130.94922578
44Phenylalanine metabolism_Homo sapiens_hsa003600.94026691
45Histidine metabolism_Homo sapiens_hsa003400.92931355
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.92814975
47MicroRNAs in cancer_Homo sapiens_hsa052060.92502351
48Prion diseases_Homo sapiens_hsa050200.92475426
49Insulin secretion_Homo sapiens_hsa049110.92154622
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.89693609
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89531736
52Adipocytokine signaling pathway_Homo sapiens_hsa049200.88271510
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88265401
54Propanoate metabolism_Homo sapiens_hsa006400.84788357
55Fatty acid metabolism_Homo sapiens_hsa012120.84353261
56Pathways in cancer_Homo sapiens_hsa052000.83991624
57Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.83095301
58Toxoplasmosis_Homo sapiens_hsa051450.83057562
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82534292
60Mineral absorption_Homo sapiens_hsa049780.81864703
61Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.81722251
62Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.81455708
63Chronic myeloid leukemia_Homo sapiens_hsa052200.81120013
64Renal cell carcinoma_Homo sapiens_hsa052110.80497056
65Linoleic acid metabolism_Homo sapiens_hsa005910.79940357
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.79487472
67Calcium signaling pathway_Homo sapiens_hsa040200.78416493
68Axon guidance_Homo sapiens_hsa043600.77999165
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76660036
70Renin-angiotensin system_Homo sapiens_hsa046140.76031219
71Platelet activation_Homo sapiens_hsa046110.75563950
72Cocaine addiction_Homo sapiens_hsa050300.74860188
73GnRH signaling pathway_Homo sapiens_hsa049120.74733085
74Dorso-ventral axis formation_Homo sapiens_hsa043200.73956773
75cAMP signaling pathway_Homo sapiens_hsa040240.73836098
76Lysine degradation_Homo sapiens_hsa003100.73438579
77Estrogen signaling pathway_Homo sapiens_hsa049150.73263932
78Notch signaling pathway_Homo sapiens_hsa043300.73115326
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72896002
80Prostate cancer_Homo sapiens_hsa052150.72448317
81Other glycan degradation_Homo sapiens_hsa005110.69860741
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68868693
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67609402
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67229760
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.67204783
86Sphingolipid metabolism_Homo sapiens_hsa006000.66894021
87Rap1 signaling pathway_Homo sapiens_hsa040150.66306815
88Arachidonic acid metabolism_Homo sapiens_hsa005900.64807696
89Endometrial cancer_Homo sapiens_hsa052130.64543979
90Pertussis_Homo sapiens_hsa051330.64408151
91Retinol metabolism_Homo sapiens_hsa008300.64353256
92Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63504439
93Pancreatic cancer_Homo sapiens_hsa052120.63263825
94Salivary secretion_Homo sapiens_hsa049700.63106453
95Insulin signaling pathway_Homo sapiens_hsa049100.63038853
96VEGF signaling pathway_Homo sapiens_hsa043700.61884156
97beta-Alanine metabolism_Homo sapiens_hsa004100.58694754
98Ras signaling pathway_Homo sapiens_hsa040140.58524551
99Circadian rhythm_Homo sapiens_hsa047100.57448546
100Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56224944
101Glioma_Homo sapiens_hsa052140.56217402
102Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54988329
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.54789450
104Oxytocin signaling pathway_Homo sapiens_hsa049210.54707346
105Glutamatergic synapse_Homo sapiens_hsa047240.54692336
106HIF-1 signaling pathway_Homo sapiens_hsa040660.52679041
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52540308
108Gastric acid secretion_Homo sapiens_hsa049710.52372353
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.51913198
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.50948796
111Glucagon signaling pathway_Homo sapiens_hsa049220.50749076
112PPAR signaling pathway_Homo sapiens_hsa033200.50619808
113AMPK signaling pathway_Homo sapiens_hsa041520.49554120
114Tyrosine metabolism_Homo sapiens_hsa003500.48394545
115mTOR signaling pathway_Homo sapiens_hsa041500.48082229
116Chemical carcinogenesis_Homo sapiens_hsa052040.47978769
117Renin secretion_Homo sapiens_hsa049240.46978221
118Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46395547
119FoxO signaling pathway_Homo sapiens_hsa040680.45981022
120Bile secretion_Homo sapiens_hsa049760.45841461
121TNF signaling pathway_Homo sapiens_hsa046680.45597704
122HTLV-I infection_Homo sapiens_hsa051660.45475281
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.45415362
124Gap junction_Homo sapiens_hsa045400.44829928
125Ether lipid metabolism_Homo sapiens_hsa005650.44260867
126Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.43760094
127Circadian entrainment_Homo sapiens_hsa047130.43572244
128Taste transduction_Homo sapiens_hsa047420.43277109
129Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42920138
130Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42623432
131Colorectal cancer_Homo sapiens_hsa052100.42249585
132Choline metabolism in cancer_Homo sapiens_hsa052310.41982863
133Thyroid hormone synthesis_Homo sapiens_hsa049180.41930160
134Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41910938
135Nitrogen metabolism_Homo sapiens_hsa009100.41665802
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41489230
137Arginine and proline metabolism_Homo sapiens_hsa003300.41421377
138MAPK signaling pathway_Homo sapiens_hsa040100.40161148
139Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.39933520
140Phagosome_Homo sapiens_hsa041450.39170798

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