CPSF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.48145059
2protein localization to kinetochore (GO:0034501)5.17270167
3nuclear pore complex assembly (GO:0051292)4.87312707
4nuclear pore organization (GO:0006999)4.84666926
5protein localization to chromosome, centromeric region (GO:0071459)4.42612243
6mitotic sister chromatid cohesion (GO:0007064)4.29534071
7mitotic nuclear envelope disassembly (GO:0007077)4.22258157
8DNA strand elongation involved in DNA replication (GO:0006271)4.21853571
9mitotic chromosome condensation (GO:0007076)4.13725647
10DNA replication initiation (GO:0006270)4.03777628
11DNA strand elongation (GO:0022616)3.99947389
12kinetochore organization (GO:0051383)3.97358126
13membrane disassembly (GO:0030397)3.95457010
14nuclear envelope disassembly (GO:0051081)3.95457010
15sister chromatid segregation (GO:0000819)3.92631631
16regulation of histone H3-K9 methylation (GO:0051570)3.89326331
17regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.89248849
18pre-miRNA processing (GO:0031054)3.86720562
19pore complex assembly (GO:0046931)3.81578534
20positive regulation of chromosome segregation (GO:0051984)3.81070310
21CENP-A containing nucleosome assembly (GO:0034080)3.80662374
22chromatin remodeling at centromere (GO:0031055)3.76224608
23telomere maintenance via semi-conservative replication (GO:0032201)3.76152784
24mitotic metaphase plate congression (GO:0007080)3.75645658
25mitotic sister chromatid segregation (GO:0000070)3.73539955
26DNA replication-dependent nucleosome assembly (GO:0006335)3.72934088
27DNA replication-dependent nucleosome organization (GO:0034723)3.72934088
28DNA duplex unwinding (GO:0032508)3.72913908
29negative regulation of DNA-dependent DNA replication (GO:2000104)3.72745810
30DNA geometric change (GO:0032392)3.71263158
31mitotic recombination (GO:0006312)3.69597569
32DNA replication checkpoint (GO:0000076)3.69407672
33attachment of spindle microtubules to kinetochore (GO:0008608)3.67676175
34DNA topological change (GO:0006265)3.66250075
35folic acid-containing compound biosynthetic process (GO:0009396)3.66086863
36DNA replication-independent nucleosome organization (GO:0034724)3.62156820
37DNA replication-independent nucleosome assembly (GO:0006336)3.62156820
38maturation of SSU-rRNA (GO:0030490)3.60049307
39regulation of centrosome duplication (GO:0010824)3.60028316
40regulation of DNA endoreduplication (GO:0032875)3.59209417
41IMP biosynthetic process (GO:0006188)3.58893649
42telomere maintenance via recombination (GO:0000722)3.58812973
43ribosomal small subunit assembly (GO:0000028)3.58199056
44regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.57114399
45non-recombinational repair (GO:0000726)3.53395163
46double-strand break repair via nonhomologous end joining (GO:0006303)3.53395163
47regulation of posttranscriptional gene silencing (GO:0060147)3.53393285
48regulation of gene silencing by miRNA (GO:0060964)3.53393285
49regulation of gene silencing by RNA (GO:0060966)3.53393285
50positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.51424115
51positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.51424115
52positive regulation of mitotic sister chromatid separation (GO:1901970)3.51424115
53formation of translation preinitiation complex (GO:0001731)3.51390119
54metaphase plate congression (GO:0051310)3.49831047
55negative regulation of histone methylation (GO:0031061)3.45741688
56regulation of RNA export from nucleus (GO:0046831)3.44361002
57ribosome assembly (GO:0042255)3.39632824
58regulation of DNA damage checkpoint (GO:2000001)3.33520579
59establishment of integrated proviral latency (GO:0075713)3.33079663
60sister chromatid cohesion (GO:0007062)3.32386158
61negative regulation of DNA repair (GO:0045738)3.31260461
62viral transcription (GO:0019083)3.30780460
63protein localization to chromosome (GO:0034502)3.30746664
64establishment of chromosome localization (GO:0051303)3.30503811
65regulation of spindle organization (GO:0090224)3.30226078
66translational termination (GO:0006415)3.29872493
67IMP metabolic process (GO:0046040)3.29810466
68histone-serine phosphorylation (GO:0035404)3.29361211
69chromatin assembly or disassembly (GO:0006333)3.28332508
70nucleobase biosynthetic process (GO:0046112)3.23964742
71histone exchange (GO:0043486)3.23659353
72somatic hypermutation of immunoglobulin genes (GO:0016446)3.21234968
73somatic diversification of immune receptors via somatic mutation (GO:0002566)3.21234968
74ATP-dependent chromatin remodeling (GO:0043044)3.21115724
75response to X-ray (GO:0010165)3.20951899
76nucleotide-excision repair, DNA gap filling (GO:0006297)3.20536763
77translesion synthesis (GO:0019985)3.18802505
78negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.18390460
79negative regulation of RNA splicing (GO:0033119)3.17343215
80meiotic chromosome segregation (GO:0045132)3.17140242
81regulation of sister chromatid cohesion (GO:0007063)3.16233866
82DNA conformation change (GO:0071103)3.14293687
83regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.11719959
84spindle checkpoint (GO:0031577)3.11158995
85telomere maintenance via telomere lengthening (GO:0010833)3.11123598
86regulation of double-strand break repair via homologous recombination (GO:0010569)3.11035321
87nuclear envelope organization (GO:0006998)3.09045584
88chromatin assembly (GO:0031497)3.08890028
89DNA double-strand break processing (GO:0000729)3.08672597
90regulation of chromosome segregation (GO:0051983)3.08641471
91negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.06854369
92regulation of mitotic metaphase/anaphase transition (GO:0030071)3.06269864
93replicative senescence (GO:0090399)3.05683563
94regulation of centrosome cycle (GO:0046605)3.05637106
95regulation of mitotic spindle organization (GO:0060236)3.05284563
96telomere maintenance (GO:0000723)3.04520021
97kinetochore assembly (GO:0051382)3.04121483
98telomere maintenance via telomerase (GO:0007004)3.03664509
99translational initiation (GO:0006413)3.03507212
100inner cell mass cell proliferation (GO:0001833)3.03499411
101purine nucleobase biosynthetic process (GO:0009113)3.03297849
102regulation of centriole replication (GO:0046599)3.02624698
103nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.02399305
104telomere organization (GO:0032200)3.00641572
105double-strand break repair via homologous recombination (GO:0000724)3.00610676
106regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.99632566
107recombinational repair (GO:0000725)2.99458244
108spindle assembly involved in mitosis (GO:0090307)2.98978519
109regulation of meiosis I (GO:0060631)2.98857273
110replication fork processing (GO:0031297)2.98146604
111somatic recombination of immunoglobulin gene segments (GO:0016447)2.97050501
112mitotic spindle checkpoint (GO:0071174)2.96337856
113spindle assembly checkpoint (GO:0071173)2.95807464
114regulation of double-strand break repair (GO:2000779)2.95203088
115regulation of translational fidelity (GO:0006450)2.94272115
116DNA synthesis involved in DNA repair (GO:0000731)2.91930037
117translational elongation (GO:0006414)2.91486380
118chromosome segregation (GO:0007059)2.91313064
119dosage compensation (GO:0007549)2.90594398
120negative regulation of mitotic sister chromatid separation (GO:2000816)2.88828200
121negative regulation of mitotic sister chromatid segregation (GO:0033048)2.88828200
122negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.88828200
123negative regulation of sister chromatid segregation (GO:0033046)2.88828200
124negative regulation of chromosome segregation (GO:0051985)2.88820480
125regulation of sister chromatid segregation (GO:0033045)2.87531810
126regulation of mitotic sister chromatid separation (GO:0010965)2.87531810
127regulation of mitotic sister chromatid segregation (GO:0033047)2.87531810
128mitotic spindle assembly checkpoint (GO:0007094)2.85886739
129postreplication repair (GO:0006301)2.85781304
130mismatch repair (GO:0006298)2.85026614
1313-UTR-mediated mRNA stabilization (GO:0070935)2.84965782

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.26819766
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.58190784
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.87765583
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.46702195
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.40827107
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.25426499
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.64166679
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53609568
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.48629720
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.46561709
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.40853259
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.37312690
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.36706435
14AR_21909140_ChIP-Seq_LNCAP_Human2.33180108
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31622206
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.30345058
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.21285527
18MYC_22102868_ChIP-Seq_BL_Human2.19969012
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.15687445
20XRN2_22483619_ChIP-Seq_HELA_Human2.14527723
21EWS_26573619_Chip-Seq_HEK293_Human2.04879434
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.03698933
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.01807361
24E2F7_22180533_ChIP-Seq_HELA_Human10.8959447
25VDR_23849224_ChIP-Seq_CD4+_Human1.99411599
26ELK1_19687146_ChIP-ChIP_HELA_Human1.97984113
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.91612845
28FUS_26573619_Chip-Seq_HEK293_Human1.90855385
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89914913
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.84773654
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83301357
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82561583
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.82116721
34MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81069145
35CIITA_25753668_ChIP-Seq_RAJI_Human1.80022726
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78516386
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.78467963
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.77080339
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.74440763
40TP63_19390658_ChIP-ChIP_HaCaT_Human1.72184129
41* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.69205378
42* TTF2_22483619_ChIP-Seq_HELA_Human1.66380152
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66108939
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.64706899
45DCP1A_22483619_ChIP-Seq_HELA_Human1.61345475
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.61303380
47JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.60842352
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.58428071
49ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57559677
50KDM5A_27292631_Chip-Seq_BREAST_Human1.49871877
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.49514368
52GABP_19822575_ChIP-Seq_HepG2_Human1.47524499
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46284105
54* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.45293135
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.43884249
56SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43688351
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43588210
58* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41809448
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.41549433
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.39430406
61BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36234673
62ZNF274_21170338_ChIP-Seq_K562_Hela1.27546117
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26418815
64SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25282248
65* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.24555476
66HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23946921
67IGF1R_20145208_ChIP-Seq_DFB_Human1.23865497
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23861835
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22898881
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.22767944
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21796959
72TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.20962877
73TFEB_21752829_ChIP-Seq_HELA_Human1.20883450
74VDR_21846776_ChIP-Seq_THP-1_Human1.20300015
75HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16239814
76ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16011584
77MYC_18940864_ChIP-ChIP_HL60_Human1.12964827
78FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11532311
79POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11123361
80SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.10872585
81* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10243672
82KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09107494
83FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.08490252
84TAF15_26573619_Chip-Seq_HEK293_Human1.08005975
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07925109
86NANOG_18555785_ChIP-Seq_MESCs_Mouse1.07819183
87VDR_22108803_ChIP-Seq_LS180_Human1.07257848
88ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07051410
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.06680974
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.06629818
91SPI1_23547873_ChIP-Seq_NB4_Human1.06207027
92ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05524495
93MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03636600
94NANOG_16153702_ChIP-ChIP_HESCs_Human1.02079159
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.02061250
96P300_19829295_ChIP-Seq_ESCs_Human1.01645796
97SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.01622199
98* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.01356871
99GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00701836
100FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00329869
101PCGF2_27294783_Chip-Seq_ESCs_Mouse0.99867975
102WT1_19549856_ChIP-ChIP_CCG9911_Human0.98396535
103STAT3_23295773_ChIP-Seq_U87_Human0.98396410
104MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.98079014
105NOTCH1_21737748_ChIP-Seq_TLL_Human0.96910524
106RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95202103
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95061150
108* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94736955
109FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.94544992
110KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94133033
111SOX2_16153702_ChIP-ChIP_HESCs_Human0.93992470
112SOX17_20123909_ChIP-Seq_XEN_Mouse0.93913494
113* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93076956
114MYB_26560356_Chip-Seq_TH2_Human0.91718465
115ER_23166858_ChIP-Seq_MCF-7_Human0.91471358
116SOX2_18555785_ChIP-Seq_MESCs_Mouse0.91260386
117TBX3_20139965_ChIP-Seq_ESCs_Mouse0.90624887
118MYB_26560356_Chip-Seq_TH1_Human0.90388532
119GBX2_23144817_ChIP-Seq_PC3_Human0.90355722
120PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90198918
121TBX3_20139965_ChIP-Seq_MESCs_Mouse0.89105591
122IRF1_19129219_ChIP-ChIP_H3396_Human0.88659407
123EZH2_27294783_Chip-Seq_NPCs_Mouse0.87671662
124GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87210802
125TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86136242
126KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.86100355
127KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.86100355
128KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.86100355
129CHD1_26751641_Chip-Seq_LNCaP_Human0.86021751
130FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84728809
131SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.84704338
132NANOG_21062744_ChIP-ChIP_HESCs_Human0.84250375
133BRD4_25478319_ChIP-Seq_HGPS_Human0.82447558
134IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81669204
135CBP_20019798_ChIP-Seq_JUKART_Human0.81669204
136UTX_26944678_Chip-Seq_JUKART_Human0.81341178
137MYB_21317192_ChIP-Seq_ERMYB_Mouse0.80520740
138POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80225199
139POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.79238867
140STAT3_1855785_ChIP-Seq_MESCs_Mouse0.78173921
141NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.77569945
142MAF_26560356_Chip-Seq_TH1_Human0.77536187
143CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.77531565
144ESR1_15608294_ChIP-ChIP_MCF-7_Human0.76603770
145PKCTHETA_26484144_Chip-Seq_BREAST_Human0.76596494
146E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.73774604

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.59894411
2MP0008057_abnormal_DNA_replication4.29466731
3MP0003693_abnormal_embryo_hatching4.22480690
4MP0003111_abnormal_nucleus_morphology3.92238607
5MP0003077_abnormal_cell_cycle3.78424554
6MP0004957_abnormal_blastocyst_morpholog3.71632268
7MP0010352_gastrointestinal_tract_polyps2.82269213
8MP0002396_abnormal_hematopoietic_system2.78124073
9MP0008007_abnormal_cellular_replicative2.66059154
10MP0008058_abnormal_DNA_repair2.61935277
11MP0010307_abnormal_tumor_latency2.36222792
12MP0000350_abnormal_cell_proliferation2.31819768
13MP0004808_abnormal_hematopoietic_stem2.30588444
14MP0001730_embryonic_growth_arrest2.29156420
15MP0003941_abnormal_skin_development2.25718975
16MP0008932_abnormal_embryonic_tissue2.25477906
17MP0003718_maternal_effect2.22031614
18MP0003123_paternal_imprinting2.18088165
19MP0009697_abnormal_copulation2.17280508
20MP0008877_abnormal_DNA_methylation2.15657998
21MP0003950_abnormal_plasma_membrane1.94503790
22MP0002009_preneoplasia1.93057460
23MP0010234_abnormal_vibrissa_follicle1.89792375
24MP0003121_genomic_imprinting1.84127857
25MP0000569_abnormal_digit_pigmentation1.74062322
26MP0006292_abnormal_olfactory_placode1.73199952
27MP0005380_embryogenesis_phenotype1.69820383
28MP0001672_abnormal_embryogenesis/_devel1.69820383
29MP0005076_abnormal_cell_differentiation1.68786464
30MP0006054_spinal_hemorrhage1.68155615
31MP0001697_abnormal_embryo_size1.67470760
32MP0000490_abnormal_crypts_of1.62676520
33MP0003984_embryonic_growth_retardation1.60659138
34MP0002088_abnormal_embryonic_growth/wei1.57156993
35MP0010678_abnormal_skin_adnexa1.55222373
36MP0002398_abnormal_bone_marrow1.54514828
37MP0002080_prenatal_lethality1.53495684
38MP0002084_abnormal_developmental_patter1.51225036
39MP0002019_abnormal_tumor_incidence1.46833777
40MP0000313_abnormal_cell_death1.46774261
41MP0002085_abnormal_embryonic_tissue1.46049072
42MP0004197_abnormal_fetal_growth/weight/1.45854815
43MP0003567_abnormal_fetal_cardiomyocyte1.44417896
44MP0002086_abnormal_extraembryonic_tissu1.42547686
45MP0000703_abnormal_thymus_morphology1.40274608
46MP0000383_abnormal_hair_follicle1.38862653
47MP0003890_abnormal_embryonic-extraembry1.38281216
48MP0001545_abnormal_hematopoietic_system1.37201522
49MP0005397_hematopoietic_system_phenotyp1.37201522
50MP0003786_premature_aging1.28931255
51MP0000427_abnormal_hair_cycle1.28848795
52MP0000689_abnormal_spleen_morphology1.28198437
53MP0002722_abnormal_immune_system1.26648578
54MP0004185_abnormal_adipocyte_glucose1.24661736
55MP0004233_abnormal_muscle_weight1.23963752
56MP0001661_extended_life_span1.23384331
57MP0001293_anophthalmia1.18154826
58MP0001915_intracranial_hemorrhage1.18066959
59MP0002102_abnormal_ear_morphology1.17609252
60MP0001800_abnormal_humoral_immune1.17389085
61MP0000537_abnormal_urethra_morphology1.17038662
62MP0009053_abnormal_anal_canal1.15553923
63MP0005174_abnormal_tail_pigmentation1.14432942
64MP0005187_abnormal_penis_morphology1.11136098
65MP0002877_abnormal_melanocyte_morpholog1.10916572
66MP0002429_abnormal_blood_cell1.07701284
67MP0001835_abnormal_antigen_presentation1.07694830
68MP0009278_abnormal_bone_marrow1.05751349
69MP0003763_abnormal_thymus_physiology1.02847523
70MP0000716_abnormal_immune_system1.02841007
71MP0002452_abnormal_antigen_presenting1.01472513
72MP0002938_white_spotting1.01232444
73MP0003787_abnormal_imprinting1.00662766
74MP0009333_abnormal_splenocyte_physiolog0.98405753
75MP0002233_abnormal_nose_morphology0.97503064
76MP0003705_abnormal_hypodermis_morpholog0.96435556
77MP0000432_abnormal_head_morphology0.96290489
78MP0000647_abnormal_sebaceous_gland0.94616658
79MP0002095_abnormal_skin_pigmentation0.94215102
80MP0003935_abnormal_craniofacial_develop0.93574444
81MP0003119_abnormal_digestive_system0.91690443
82MP0002420_abnormal_adaptive_immunity0.90988005
83MP0002006_tumorigenesis0.90827302
84MP0003315_abnormal_perineum_morphology0.90718721
85MP0003755_abnormal_palate_morphology0.90416626
86MP0002160_abnormal_reproductive_system0.90194427
87MP0005395_other_phenotype0.89872113
88MP0003566_abnormal_cell_adhesion0.89700770
89MP0001819_abnormal_immune_cell0.88455124
90MP0000733_abnormal_muscle_development0.88448782
91MP0002234_abnormal_pharynx_morphology0.87516285
92MP0003303_peritoneal_inflammation0.87391593
93MP0005408_hypopigmentation0.86367076
94MP0005621_abnormal_cell_physiology0.84977177
95MP0010030_abnormal_orbit_morphology0.84945669
96MP0003937_abnormal_limbs/digits/tail_de0.84471800
97MP0005384_cellular_phenotype0.83324991
98MP0001929_abnormal_gametogenesis0.83040673
99MP0002166_altered_tumor_susceptibility0.82959530
100MP0003221_abnormal_cardiomyocyte_apopto0.82151535
101MP0002098_abnormal_vibrissa_morphology0.81434459
102MP0000627_abnormal_mammary_gland0.77820918
103MP0002210_abnormal_sex_determination0.77321317
104MP0000566_synostosis0.76744949
105MP0009672_abnormal_birth_weight0.76169249
106MP0002092_abnormal_eye_morphology0.75449624
107MP0002723_abnormal_immune_serum0.75221454
108MP0008789_abnormal_olfactory_epithelium0.74359073
109MP0009703_decreased_birth_body0.73959657
110MP0000579_abnormal_nail_morphology0.73662197
111MP0003385_abnormal_body_wall0.73510737
112MP0001286_abnormal_eye_development0.73170995
113MP0002177_abnormal_outer_ear0.73132293
114MP0003300_gastrointestinal_ulcer0.73049576
115MP0003943_abnormal_hepatobiliary_system0.72783792
116MP0005171_absent_coat_pigmentation0.72772256
117MP0000015_abnormal_ear_pigmentation0.71609176
118MP0000371_diluted_coat_color0.70273999
119MP0000428_abnormal_craniofacial_morphol0.70015057
120MP0009379_abnormal_foot_pigmentation0.69062433
121MP0001145_abnormal_male_reproductive0.68899129
122MP0000653_abnormal_sex_gland0.68897680
123MP0002254_reproductive_system_inflammat0.68345065
124MP0000858_altered_metastatic_potential0.67721159
125MP0000465_gastrointestinal_hemorrhage0.67587134
126MP0000377_abnormal_hair_follicle0.67391813
127MP0003936_abnormal_reproductive_system0.67323096
128MP0008770_decreased_survivor_rate0.66842154
129MP0002925_abnormal_cardiovascular_devel0.66200256
130MP0002697_abnormal_eye_size0.65189498
131MP0002405_respiratory_system_inflammati0.64841913
132MP0003699_abnormal_female_reproductive0.63890270
133MP0006035_abnormal_mitochondrial_morpho0.63567181
134MP0004272_abnormal_basement_membrane0.63436616
135MP0003136_yellow_coat_color0.62303608
136MP0005387_immune_system_phenotype0.61985754
137MP0001790_abnormal_immune_system0.61985754
138MP0005647_abnormal_sex_gland0.61882528
139MP0003646_muscle_fatigue0.61842905
140MP0003861_abnormal_nervous_system0.61658765
141MP0000358_abnormal_cell_content/0.61364840
142MP0003448_altered_tumor_morphology0.61324831
143MP0005023_abnormal_wound_healing0.60716567
144MP0001186_pigmentation_phenotype0.60684646
145MP0002111_abnormal_tail_morphology0.60091398

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.85594872
2Chromsome breakage (HP:0040012)3.67375552
3Colon cancer (HP:0003003)3.38063763
4Reticulocytopenia (HP:0001896)3.35051023
5Birth length less than 3rd percentile (HP:0003561)3.34845276
6Abnormality of chromosome stability (HP:0003220)3.18397374
7Medulloblastoma (HP:0002885)3.16969560
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.11070832
9Agnosia (HP:0010524)2.99465196
10Selective tooth agenesis (HP:0001592)2.93704226
11Cutaneous melanoma (HP:0012056)2.87467106
12Ependymoma (HP:0002888)2.85262441
13Abnormal number of incisors (HP:0011064)2.72281986
14Papillary thyroid carcinoma (HP:0002895)2.71962314
15Increased nuchal translucency (HP:0010880)2.68931700
16Cellulitis (HP:0100658)2.67678879
17Myelodysplasia (HP:0002863)2.66747433
18Abnormality of cells of the erythroid lineage (HP:0012130)2.60679229
19Absent radius (HP:0003974)2.55590922
20Neoplasm of the adrenal cortex (HP:0100641)2.53133528
21Rhabdomyosarcoma (HP:0002859)2.48680475
22Deviation of the thumb (HP:0009603)2.48178272
23Proximal placement of thumb (HP:0009623)2.47638946
24Basal cell carcinoma (HP:0002671)2.46192237
25Abnormal number of erythroid precursors (HP:0012131)2.43749728
26Acute myeloid leukemia (HP:0004808)2.40885739
27Clubbing of toes (HP:0100760)2.39626436
28Hypoplastic labia majora (HP:0000059)2.39220751
29IgM deficiency (HP:0002850)2.36915455
30Abnormality of the anterior horn cell (HP:0006802)2.36586931
31Degeneration of anterior horn cells (HP:0002398)2.36586931
32Patellar aplasia (HP:0006443)2.35137226
33Ectopic kidney (HP:0000086)2.35063261
34Aplasia involving forearm bones (HP:0009822)2.35048283
35Absent forearm bone (HP:0003953)2.35048283
36Prominent nose (HP:0000448)2.34525165
37Duplicated collecting system (HP:0000081)2.30478682
38Increased density of long bones (HP:0006392)2.29533815
39Small intestinal stenosis (HP:0012848)2.28851504
40Duodenal stenosis (HP:0100867)2.28851504
41Short 4th metacarpal (HP:0010044)2.27392723
42Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.27392723
43Aplasia/Hypoplasia of the uvula (HP:0010293)2.27222622
44Lymphoma (HP:0002665)2.26468569
45Abnormality of the preputium (HP:0100587)2.26266724
46Meckel diverticulum (HP:0002245)2.25592790
47Pallor (HP:0000980)2.25468339
48Capillary hemangiomas (HP:0005306)2.23660762
49Aplastic anemia (HP:0001915)2.22253038
50Agammaglobulinemia (HP:0004432)2.20900582
51Squamous cell carcinoma (HP:0002860)2.20620610
5211 pairs of ribs (HP:0000878)2.19851619
53High pitched voice (HP:0001620)2.19653653
54Abnormality of the labia majora (HP:0012881)2.19273563
55Aplasia/Hypoplasia of the patella (HP:0006498)2.19205440
56Pelvic girdle muscle weakness (HP:0003749)2.18925145
57Biliary tract neoplasm (HP:0100574)2.17835986
58Atresia of the external auditory canal (HP:0000413)2.17709522
59Recurrent viral infections (HP:0004429)2.16455300
60Abnormality of chromosome segregation (HP:0002916)2.16260802
61Hypoplasia of the capital femoral epiphysis (HP:0003090)2.15656965
62Thrombocytosis (HP:0001894)2.15358810
63Triphalangeal thumb (HP:0001199)2.14946649
64Embryonal neoplasm (HP:0002898)2.14601971
65Abnormality of the ileum (HP:0001549)2.14359083
66Cafe-au-lait spot (HP:0000957)2.11779206
67Abnormality of the renal collecting system (HP:0004742)2.10629224
68Abnormal lung lobation (HP:0002101)2.10259586
69Abnormality of the astrocytes (HP:0100707)2.09523697
70Astrocytoma (HP:0009592)2.09523697
71Breast hypoplasia (HP:0003187)2.08748052
72Cutis marmorata (HP:0000965)2.08031634
73Amaurosis fugax (HP:0100576)2.05373082
74Verrucae (HP:0200043)2.04832773
75Papilloma (HP:0012740)2.04832773
76Breast carcinoma (HP:0003002)2.02863730
77Abnormality of the labia minora (HP:0012880)2.00747198
78Abnormality of the pons (HP:0007361)2.00568647
79Syringomyelia (HP:0003396)1.98650285
80Spinal cord lesions (HP:0100561)1.98650285
81Absent thumb (HP:0009777)1.97684612
82Fair hair (HP:0002286)1.97655746
83Deep philtrum (HP:0002002)1.97038647
84Gastrointestinal carcinoma (HP:0002672)1.96995306
85Malignant gastrointestinal tract tumors (HP:0006749)1.96995306
86Glioma (HP:0009733)1.96707184
87Abnormality of the fingertips (HP:0001211)1.95123584
88Protruding tongue (HP:0010808)1.94073499
89Neoplasm of the pancreas (HP:0002894)1.93406735
90Sloping forehead (HP:0000340)1.92406979
91Long eyelashes (HP:0000527)1.91986600
92Small hand (HP:0200055)1.90805449
93Neoplasm of the colon (HP:0100273)1.87866255
94Nephroblastoma (Wilms tumor) (HP:0002667)1.87488599
95Supernumerary spleens (HP:0009799)1.86916069
96Cystic hygroma (HP:0000476)1.86735448
97Abnormality of alanine metabolism (HP:0010916)1.85901347
98Hyperalaninemia (HP:0003348)1.85901347
99Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.85901347
100Thyroid carcinoma (HP:0002890)1.85886192
101Acute lymphatic leukemia (HP:0006721)1.85581862
102Curly hair (HP:0002212)1.84862736
103Abnormality of the duodenum (HP:0002246)1.84234161
104Oral leukoplakia (HP:0002745)1.84040023
105Osteomyelitis (HP:0002754)1.82031480
106Abnormality of the hip-girdle musculature (HP:0001445)1.81020243
107Abnormality of the musculature of the pelvis (HP:0001469)1.81020243
108Bone marrow hypocellularity (HP:0005528)1.80558754
109Arteriovenous malformation (HP:0100026)1.80273054
110Neoplasm of striated muscle (HP:0009728)1.80221025
111Clitoromegaly (HP:0000057)1.79567857
112Cortical dysplasia (HP:0002539)1.79561772
113Aplasia/Hypoplasia of the sternum (HP:0006714)1.78941716
114Macrocytic anemia (HP:0001972)1.78730887
115Abnormality of B cell number (HP:0010975)1.78409515
116B lymphocytopenia (HP:0010976)1.78409515
117Shoulder girdle muscle weakness (HP:0003547)1.78049622
118Abnormality of cochlea (HP:0000375)1.77687434
119Cellular immunodeficiency (HP:0005374)1.77362690
120Progressive inability to walk (HP:0002505)1.77325994
121Abnormality of the carotid arteries (HP:0005344)1.77012026
122Asymmetry of the thorax (HP:0001555)1.76137475
123Horseshoe kidney (HP:0000085)1.75238644
124Embryonal renal neoplasm (HP:0011794)1.75050948
125Transitional cell carcinoma of the bladder (HP:0006740)1.74135732
126Recurrent bronchitis (HP:0002837)1.73264123
127Sandal gap (HP:0001852)1.72203068
128Impulsivity (HP:0100710)1.71704710
129Premature graying of hair (HP:0002216)1.71510653
130Uterine neoplasm (HP:0010784)1.71457543
131Esophageal atresia (HP:0002032)1.70834825
132Neoplasm of the rectum (HP:0100743)1.70784780
133Neoplasm of the small intestine (HP:0100833)1.70415628
134Choanal atresia (HP:0000453)1.70176938
135Neoplasm of the oral cavity (HP:0100649)1.69881269
136Low anterior hairline (HP:0000294)1.69807056
137Gonadotropin excess (HP:0000837)1.69674783
138Partial agenesis of the corpus callosum (HP:0001338)1.69413163
139Leiomyosarcoma (HP:0100243)1.69410659
140Uterine leiomyosarcoma (HP:0002891)1.69410659
141IgG deficiency (HP:0004315)1.68440061
142Microglossia (HP:0000171)1.68394762
143High anterior hairline (HP:0009890)1.67979483
144Short thumb (HP:0009778)1.67479296
145Bladder neoplasm (HP:0009725)1.65722768
146Bladder carcinoma (HP:0002862)1.65722768
147Abnormal biliary tract morphology (HP:0012440)1.65695717
148Gastrointestinal atresia (HP:0002589)1.65546723
149Abnormality of DNA repair (HP:0003254)1.65520016
150Central scotoma (HP:0000603)1.64976991
151Facial hemangioma (HP:0000329)1.64551403
152Neoplasm of the adrenal gland (HP:0100631)1.62667371
153Aplasia cutis congenita (HP:0001057)1.62620723
154Oligodactyly (hands) (HP:0001180)1.61359892
155Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.60411985
156Aplasia/Hypoplasia of the tibia (HP:0005772)1.60368289
157Hypoplasia of the pons (HP:0012110)1.59789231

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.00146803
2WEE13.63876341
3BUB13.22232788
4MAP3K103.08881102
5FRK2.96213199
6NEK22.56289144
7EEF2K2.40359680
8SRPK12.38435917
9EIF2AK12.35030415
10MKNK12.25127675
11TAF12.11772292
12BRSK22.08187566
13STK102.07097572
14TTK2.04270610
15BMPR1B1.95798571
16TSSK61.88484906
17ACVR1B1.87132857
18PASK1.85314119
19PLK31.82447805
20ATR1.79551934
21CDK121.77104316
22STK38L1.76010347
23MKNK21.75947870
24RPS6KB21.71376435
25SCYL21.69423472
26STK31.67608335
27STK41.66481346
28PKN21.66146784
29PLK11.62753586
30AURKB1.62448354
31TLK11.62362947
32PLK41.60368868
33TGFBR11.59992984
34CDK41.56869007
35RPS6KA41.49436522
36MAP3K81.44911784
37CHEK21.40563909
38CHEK11.38808173
39NEK11.35943185
40CAMK1G1.32075974
41MAP4K11.31508099
42LRRK21.31326747
43CDK61.30434907
44ALK1.26389234
45AKT31.24996784
46BRD41.24791349
47MET1.23781333
48CDK71.23586251
49VRK11.22244022
50BRSK11.20207894
51DYRK31.20145156
52CAMK1D1.12576789
53STK391.11587043
54TESK21.08709139
55ATM1.07995690
56EIF2AK31.02181099
57PIM10.97116211
58AURKA0.96535766
59ERBB40.94406721
60CDK20.93897286
61STK240.91296440
62PBK0.91046261
63PLK20.89400837
64GRK60.85441937
65BTK0.84829010
66NME20.82272058
67ZAK0.81808581
68ERBB30.81442481
69NUAK10.78992949
70MELK0.74913465
71TRIM280.74449155
72PAK40.68601438
73CDK10.68575071
74CLK10.67763590
75JAK30.67596529
76WNK30.61387591
77CSNK2A20.60957132
78FLT30.58383193
79NEK90.57917877
80SYK0.53708352
81KSR10.53327975
82TNIK0.52836119
83CDK90.52346789
84CSNK1G10.51943306
85LATS20.51721486
86MAP3K90.51422247
87MARK30.51199275
88RPS6KA50.50622290
89BRAF0.49372434
90AKT20.48587133
91MTOR0.48501862
92PRKDC0.48148303
93WNK40.47526777
94KIT0.47426772
95PNCK0.47043888
96WNK10.45152113
97MAP3K50.45083946
98YES10.44529930
99CSNK2A10.44073393
100CSF1R0.43287283
101ILK0.42132184
102CCNB10.41654313
103MST1R0.41366455
104BCR0.41326806
105RAF10.41177411
106TEC0.40459700
107PAK10.40026902
108CDK80.39756913
109CSNK1D0.39003005
110CSNK1E0.38987852
111CSNK1A1L0.38962684
112SGK20.38506957
113MAPK140.38174537
114PAK20.36687422
115MATK0.36285121
116LYN0.35917167
117CDK30.35694592
118FGFR10.32975958
119OXSR10.31212762
120MST40.29921074
121MAPKAPK50.28994902
122RPS6KB10.28368175
123MAPKAPK20.27994620
124PIM20.27589755
125PRKCI0.27369720
126MAP3K60.26247399
127EIF2AK20.26128135
128LATS10.25966120

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.26648035
2Mismatch repair_Homo sapiens_hsa034303.86266356
3Cell cycle_Homo sapiens_hsa041102.99859702
4Spliceosome_Homo sapiens_hsa030402.94859778
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.92117090
6RNA transport_Homo sapiens_hsa030132.85338971
7Base excision repair_Homo sapiens_hsa034102.56738110
8Homologous recombination_Homo sapiens_hsa034402.54658163
9Ribosome_Homo sapiens_hsa030102.54125594
10Selenocompound metabolism_Homo sapiens_hsa004502.49928621
11Nucleotide excision repair_Homo sapiens_hsa034202.43456351
12Non-homologous end-joining_Homo sapiens_hsa034502.38207690
13One carbon pool by folate_Homo sapiens_hsa006702.28343662
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16992258
15RNA polymerase_Homo sapiens_hsa030202.13437116
16Fanconi anemia pathway_Homo sapiens_hsa034602.07067533
17Proteasome_Homo sapiens_hsa030502.00921150
18RNA degradation_Homo sapiens_hsa030181.94707213
19Protein export_Homo sapiens_hsa030601.89177580
20* mRNA surveillance pathway_Homo sapiens_hsa030151.86032457
21Systemic lupus erythematosus_Homo sapiens_hsa053221.80721413
22Pyrimidine metabolism_Homo sapiens_hsa002401.63346691
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.61922719
24p53 signaling pathway_Homo sapiens_hsa041151.56198188
25Viral carcinogenesis_Homo sapiens_hsa052031.50857262
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.45636388
27Basal transcription factors_Homo sapiens_hsa030221.45413643
28Epstein-Barr virus infection_Homo sapiens_hsa051691.44403888
29Propanoate metabolism_Homo sapiens_hsa006401.39707102
30Lysine degradation_Homo sapiens_hsa003101.34426975
31Vitamin B6 metabolism_Homo sapiens_hsa007501.34149448
32Oocyte meiosis_Homo sapiens_hsa041141.30391962
33Herpes simplex infection_Homo sapiens_hsa051681.24751401
34Antigen processing and presentation_Homo sapiens_hsa046121.20620094
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.20600797
36Primary immunodeficiency_Homo sapiens_hsa053401.19259079
37MicroRNAs in cancer_Homo sapiens_hsa052061.18459449
38B cell receptor signaling pathway_Homo sapiens_hsa046621.16563931
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.15212587
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10575270
41Chronic myeloid leukemia_Homo sapiens_hsa052201.06025322
42HTLV-I infection_Homo sapiens_hsa051661.05902007
43Small cell lung cancer_Homo sapiens_hsa052221.03346870
44Steroid biosynthesis_Homo sapiens_hsa001000.98662307
45Colorectal cancer_Homo sapiens_hsa052100.98418403
46Alcoholism_Homo sapiens_hsa050340.97810303
47Hepatitis B_Homo sapiens_hsa051610.95199231
48Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.91134723
49NF-kappa B signaling pathway_Homo sapiens_hsa040640.89670017
50Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88528983
51Pyruvate metabolism_Homo sapiens_hsa006200.87920555
52Legionellosis_Homo sapiens_hsa051340.87520438
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87277428
54Measles_Homo sapiens_hsa051620.86628067
55Shigellosis_Homo sapiens_hsa051310.83059294
56Non-small cell lung cancer_Homo sapiens_hsa052230.80946574
57Purine metabolism_Homo sapiens_hsa002300.76926384
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.76137035
59Leishmaniasis_Homo sapiens_hsa051400.75745912
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75239329
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.73895564
62Pancreatic cancer_Homo sapiens_hsa052120.73606873
63Apoptosis_Homo sapiens_hsa042100.72961999
64Basal cell carcinoma_Homo sapiens_hsa052170.72260690
65Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71003414
66Viral myocarditis_Homo sapiens_hsa054160.70822444
67Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70636079
68NOD-like receptor signaling pathway_Homo sapiens_hsa046210.70327923
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70039225
70Thyroid cancer_Homo sapiens_hsa052160.69441649
71Hematopoietic cell lineage_Homo sapiens_hsa046400.67571789
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66096417
73Hedgehog signaling pathway_Homo sapiens_hsa043400.62856574
74TGF-beta signaling pathway_Homo sapiens_hsa043500.62829125
75Acute myeloid leukemia_Homo sapiens_hsa052210.60133178
76Intestinal immune network for IgA production_Homo sapiens_hsa046720.60116563
77Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59192760
78Influenza A_Homo sapiens_hsa051640.58832101
79HIF-1 signaling pathway_Homo sapiens_hsa040660.57020737
80Glioma_Homo sapiens_hsa052140.54906563
81Prostate cancer_Homo sapiens_hsa052150.53727049
82Hippo signaling pathway_Homo sapiens_hsa043900.53143370
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.52653708
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51513600
85Fatty acid biosynthesis_Homo sapiens_hsa000610.51163934
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49859090
87Proteoglycans in cancer_Homo sapiens_hsa052050.49471921
88Toxoplasmosis_Homo sapiens_hsa051450.49168621
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.48731569
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48541043
91Tight junction_Homo sapiens_hsa045300.47879458
92Caffeine metabolism_Homo sapiens_hsa002320.47658777
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47261618
94Pathways in cancer_Homo sapiens_hsa052000.46760994
95Osteoclast differentiation_Homo sapiens_hsa043800.46519108
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46302526
97Endometrial cancer_Homo sapiens_hsa052130.46156320
98FoxO signaling pathway_Homo sapiens_hsa040680.46129749
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46052494
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.45877631
101Biosynthesis of amino acids_Homo sapiens_hsa012300.45402030
102T cell receptor signaling pathway_Homo sapiens_hsa046600.45020908
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44687316
104Adherens junction_Homo sapiens_hsa045200.44347638
105mTOR signaling pathway_Homo sapiens_hsa041500.43594364
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43538517
107Platelet activation_Homo sapiens_hsa046110.43154082
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.43000513
109Asthma_Homo sapiens_hsa053100.42180597
110Tuberculosis_Homo sapiens_hsa051520.41488963
111Dorso-ventral axis formation_Homo sapiens_hsa043200.40726873
112Bladder cancer_Homo sapiens_hsa052190.39017126
113Butanoate metabolism_Homo sapiens_hsa006500.38927437
114Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38243867
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.36871442
116Toll-like receptor signaling pathway_Homo sapiens_hsa046200.35637871
117Salmonella infection_Homo sapiens_hsa051320.34280141
118Renal cell carcinoma_Homo sapiens_hsa052110.33890962
119Melanoma_Homo sapiens_hsa052180.33672807
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.33227884
121TNF signaling pathway_Homo sapiens_hsa046680.33208736
122Fatty acid metabolism_Homo sapiens_hsa012120.32777752
123Tryptophan metabolism_Homo sapiens_hsa003800.32242370
124N-Glycan biosynthesis_Homo sapiens_hsa005100.31787676
125Pertussis_Homo sapiens_hsa051330.31497916
126VEGF signaling pathway_Homo sapiens_hsa043700.31086863
127Folate biosynthesis_Homo sapiens_hsa007900.30219085
128Wnt signaling pathway_Homo sapiens_hsa043100.30055176
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29759943
130Notch signaling pathway_Homo sapiens_hsa043300.29706146
131Pentose phosphate pathway_Homo sapiens_hsa000300.29649024
132Phototransduction_Homo sapiens_hsa047440.28027298
133Ether lipid metabolism_Homo sapiens_hsa005650.26892031
134Nitrogen metabolism_Homo sapiens_hsa009100.23141642
135Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.22645251
136ABC transporters_Homo sapiens_hsa020100.20960418
137Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.20207514
138Longevity regulating pathway - mammal_Homo sapiens_hsa042110.19490457
139beta-Alanine metabolism_Homo sapiens_hsa004100.18300154
140Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.17291756
141Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.16507102
142Carbon metabolism_Homo sapiens_hsa012000.16350302
143Olfactory transduction_Homo sapiens_hsa047400.15413511
144Metabolic pathways_Homo sapiens_hsa011000.14507258

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