COPG2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)4.84004261
2synaptic vesicle maturation (GO:0016188)4.33751465
3paraxial mesoderm development (GO:0048339)4.25397280
4nuclear pore complex assembly (GO:0051292)4.21884837
5establishment of nucleus localization (GO:0040023)3.99601268
6DNA unwinding involved in DNA replication (GO:0006268)3.73625815
7nuclear pore organization (GO:0006999)3.66134437
8locomotory exploration behavior (GO:0035641)3.66065498
9peptidyl-lysine dimethylation (GO:0018027)3.65764234
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.56988030
11cell migration in hindbrain (GO:0021535)3.55840383
12regulation of short-term neuronal synaptic plasticity (GO:0048172)3.50803060
13negative regulation of DNA repair (GO:0045738)3.33620872
14pre-miRNA processing (GO:0031054)3.31899409
15vesicle transport along microtubule (GO:0047496)3.28192399
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.27179649
17negative regulation of organelle assembly (GO:1902116)3.26977278
18sodium ion export (GO:0071436)3.26932340
19synaptic vesicle docking involved in exocytosis (GO:0016081)3.25941510
20cytoskeletal anchoring at plasma membrane (GO:0007016)3.24725250
21notochord development (GO:0030903)3.20337759
22activation of protein kinase A activity (GO:0034199)3.14679353
23cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.07470726
24positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.05853743
25glial cell proliferation (GO:0014009)3.05364197
26proline transport (GO:0015824)3.02946009
27mitotic sister chromatid cohesion (GO:0007064)3.02726114
28regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.98999373
29regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.98717522
30dendritic spine morphogenesis (GO:0060997)2.98089651
31cell communication by electrical coupling (GO:0010644)2.97895222
32convergent extension (GO:0060026)2.97405428
33protein-DNA complex disassembly (GO:0032986)2.96441496
34nucleosome disassembly (GO:0006337)2.96441496
35sister chromatid segregation (GO:0000819)2.96427080
36protein localization to kinetochore (GO:0034501)2.95468644
37regulation of glutamate receptor signaling pathway (GO:1900449)2.95351464
38synaptic vesicle exocytosis (GO:0016079)2.92597095
39presynaptic membrane assembly (GO:0097105)2.91965023
40pore complex assembly (GO:0046931)2.90231623
41regulation of dendritic spine morphogenesis (GO:0061001)2.90017503
42mitotic sister chromatid segregation (GO:0000070)2.88708062
43glutamate secretion (GO:0014047)2.87240192
44regulation of synaptic vesicle exocytosis (GO:2000300)2.86500338
45mating behavior (GO:0007617)2.86201432
46regulation of Rac protein signal transduction (GO:0035020)2.82985895
47exploration behavior (GO:0035640)2.82714866
48regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.78617857
49vocalization behavior (GO:0071625)2.75537584
50insulin-like growth factor receptor signaling pathway (GO:0048009)2.74963141
51axonal fasciculation (GO:0007413)2.74057411
52regulation of clathrin-mediated endocytosis (GO:2000369)2.73588716
53cytoplasmic mRNA processing body assembly (GO:0033962)2.72812259
54neuron cell-cell adhesion (GO:0007158)2.71888335
55nucleus localization (GO:0051647)2.70784549
56dendrite morphogenesis (GO:0048813)2.68350108
57neurotransmitter secretion (GO:0007269)2.68074508
58protein localization to chromosome, centromeric region (GO:0071459)2.66805393
59presynaptic membrane organization (GO:0097090)2.66802947
60neuromuscular process controlling balance (GO:0050885)2.66262500
61suckling behavior (GO:0001967)2.65182075
62heterochromatin organization (GO:0070828)2.65109331
63protein localization to synapse (GO:0035418)2.61928260
64glucocorticoid receptor signaling pathway (GO:0042921)2.61160112
65positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.60487995
66positive regulation of cell cycle G2/M phase transition (GO:1902751)2.60487995
67Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.59970692
68organelle transport along microtubule (GO:0072384)2.59813094
69proximal/distal pattern formation (GO:0009954)2.58481182
70regulation of neuronal synaptic plasticity (GO:0048168)2.57142343
71innervation (GO:0060384)2.57026975
72protein localization to endosome (GO:0036010)2.54392025
73clathrin coat assembly (GO:0048268)2.53671267
74body morphogenesis (GO:0010171)2.53059381
75mitotic chromosome condensation (GO:0007076)2.52984281
76neuron recognition (GO:0008038)2.52726669
77regulation of long-term neuronal synaptic plasticity (GO:0048169)2.52680146
78regulation of gene silencing by RNA (GO:0060966)2.52474723
79regulation of posttranscriptional gene silencing (GO:0060147)2.52474723
80regulation of gene silencing by miRNA (GO:0060964)2.52474723
81apical protein localization (GO:0045176)2.52118629
82negative regulation of potassium ion transmembrane transport (GO:1901380)2.52109148
83DNA topological change (GO:0006265)2.51255231
84positive regulation of dendritic spine morphogenesis (GO:0061003)2.50877530
85regulation of establishment of planar polarity (GO:0090175)2.49944329
86embryonic foregut morphogenesis (GO:0048617)2.49586248
87regulation of ARF protein signal transduction (GO:0032012)2.49553326
88regulation of synapse structural plasticity (GO:0051823)2.48622768
89neuron projection extension involved in neuron projection guidance (GO:1902284)2.46865073
90axon extension involved in axon guidance (GO:0048846)2.46865073
91regulation of protein polyubiquitination (GO:1902914)2.46614723
92negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.46439644
93hippo signaling (GO:0035329)2.46401811
94negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.46161505
95axon extension (GO:0048675)2.44236120
96negative regulation of sodium ion transport (GO:0010766)2.43263664
97regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.42744930
98postsynaptic membrane organization (GO:0001941)2.42459936
99cerebellar Purkinje cell layer development (GO:0021680)2.42328429
100negative regulation of cell size (GO:0045792)2.40915198
101synaptic vesicle endocytosis (GO:0048488)2.39910417
102regulation of translational fidelity (GO:0006450)2.38907597
103membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.38395555
104establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.38354812
105mitochondrion transport along microtubule (GO:0047497)2.38354812
106hindbrain development (GO:0030902)2.37855414
107cell communication involved in cardiac conduction (GO:0086065)2.37419586
108gastrulation with mouth forming second (GO:0001702)2.35620440
109negative regulation of catenin import into nucleus (GO:0035414)2.30860935
110ionotropic glutamate receptor signaling pathway (GO:0035235)2.30067813
111positive regulation of dendrite morphogenesis (GO:0050775)2.30030138
112establishment of mitochondrion localization (GO:0051654)2.30013608
113prepulse inhibition (GO:0060134)2.29738949
114axon cargo transport (GO:0008088)2.29688010
115negative regulation of microtubule polymerization (GO:0031115)2.29578302
116lateral sprouting from an epithelium (GO:0060601)2.29573465
117mitotic cytokinesis (GO:0000281)2.28038468
118cellular sodium ion homeostasis (GO:0006883)2.27837106
119G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.25913737
120myotube differentiation (GO:0014902)2.25702617
121regulation of cell fate specification (GO:0042659)2.25676047
122regulation of cAMP-dependent protein kinase activity (GO:2000479)2.25528573
123non-canonical Wnt signaling pathway (GO:0035567)2.25515743
124establishment of integrated proviral latency (GO:0075713)2.25111101
125peptidyl-arginine methylation (GO:0018216)2.25025113
126peptidyl-arginine N-methylation (GO:0035246)2.25025113
127establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.24787625
128NLS-bearing protein import into nucleus (GO:0006607)2.23691842
129regulation of NFAT protein import into nucleus (GO:0051532)2.23600823
130negative regulation of histone methylation (GO:0031061)2.23407486
131generation of neurons (GO:0048699)2.23217540
132cellular potassium ion homeostasis (GO:0030007)2.22903894
133asymmetric protein localization (GO:0008105)2.22886547
134protein complex localization (GO:0031503)2.22800905
135midgut development (GO:0007494)2.22444909
136protein localization to chromosome (GO:0034502)2.22433850
137corticosteroid receptor signaling pathway (GO:0031958)2.20522846
138peptidyl-arginine omega-N-methylation (GO:0035247)2.19981211
139positive regulation of synapse maturation (GO:0090129)2.19023165
140dorsal/ventral axis specification (GO:0009950)2.17153228
141regulation of synaptic vesicle transport (GO:1902803)2.16937468
142embryonic body morphogenesis (GO:0010172)2.16614467
143regulation of RNA export from nucleus (GO:0046831)2.16591454
144ectodermal placode formation (GO:0060788)2.16541392
145protein localization to microtubule (GO:0035372)2.16520848
146lung-associated mesenchyme development (GO:0060484)2.16132002
147behavioral defense response (GO:0002209)2.15857939
148behavioral fear response (GO:0001662)2.15857939
149establishment of planar polarity (GO:0001736)2.15820450
150establishment of tissue polarity (GO:0007164)2.15820450
151cerebral cortex neuron differentiation (GO:0021895)2.15784751
152L-serine metabolic process (GO:0006563)2.14663192
153pyrimidine nucleobase catabolic process (GO:0006208)2.13573256
154embryonic camera-type eye morphogenesis (GO:0048596)2.13541578
155cerebellar Purkinje cell differentiation (GO:0021702)2.13501891
156planar cell polarity pathway involved in neural tube closure (GO:0090179)2.12851147
157neuronal ion channel clustering (GO:0045161)2.12284234
158G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.12007920
159lysine metabolic process (GO:0006553)2.11478455
160lysine catabolic process (GO:0006554)2.11478455
161establishment or maintenance of monopolar cell polarity (GO:0061339)2.11255113
162establishment of monopolar cell polarity (GO:0061162)2.11255113
163regulation of sister chromatid cohesion (GO:0007063)2.10090103
164regulation of histone H3-K9 methylation (GO:0051570)2.09466425
165positive regulation of SMAD protein import into nucleus (GO:0060391)2.08627292
166regulation of mitotic spindle organization (GO:0060236)2.08200890
167regulation of centriole replication (GO:0046599)2.07831822
168camera-type eye morphogenesis (GO:0048593)2.06362209
169negative regulation of chondrocyte differentiation (GO:0032331)2.05230424
170mitotic spindle organization (GO:0007052)2.04529557
171embryonic eye morphogenesis (GO:0048048)2.04231836
172ATP-dependent chromatin remodeling (GO:0043044)2.03579701
173establishment or maintenance of bipolar cell polarity (GO:0061245)2.03324584
174establishment or maintenance of apical/basal cell polarity (GO:0035088)2.03324584
175neuronal stem cell maintenance (GO:0097150)2.01716413

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.98905159
2ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.86174198
3STAT6_21828071_ChIP-Seq_BEAS2B_Human2.43981771
4ZFP281_18757296_ChIP-ChIP_E14_Mouse2.43388052
5ZNF263_19887448_ChIP-Seq_K562_Human2.39475765
6RARB_27405468_Chip-Seq_BRAIN_Mouse2.24293656
7WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.21388886
8TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.19301809
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.17052854
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.13651633
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.11244030
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.11244030
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.09556214
14ESR1_15608294_ChIP-ChIP_MCF-7_Human2.08976896
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.06478659
16SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.95468290
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.91451767
18EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.91379108
19DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.90873204
20DROSHA_22980978_ChIP-Seq_HELA_Human1.87958835
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.87297784
22ZFP281_27345836_Chip-Seq_ESCs_Mouse1.85731561
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.85154799
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.82085337
25ERG_21242973_ChIP-ChIP_JURKAT_Human1.81558288
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.81123832
27NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.76432096
28SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.75798416
29AR_21909140_ChIP-Seq_LNCAP_Human1.75507673
30KDM2B_26808549_Chip-Seq_K562_Human1.69717464
31EZH2_27304074_Chip-Seq_ESCs_Mouse1.69666263
32ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.69465475
33FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.66477773
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.66362517
35RNF2_27304074_Chip-Seq_ESCs_Mouse1.65128119
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63429483
37MTF2_20144788_ChIP-Seq_MESCs_Mouse1.59438389
38SOX2_16153702_ChIP-ChIP_HESCs_Human1.56552260
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.56242484
40SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.55719436
41SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.55112642
42RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.55055607
43EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.51110960
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.48144629
45SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.48144005
46KDM2B_26808549_Chip-Seq_JURKAT_Human1.47205047
47AR_21572438_ChIP-Seq_LNCaP_Human1.44398930
48SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.43919522
49SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.43507883
50REST_18959480_ChIP-ChIP_MESCs_Mouse1.43014583
51RING1B_27294783_Chip-Seq_NPCs_Mouse1.41951747
52SOX9_26525672_Chip-Seq_HEART_Mouse1.41598855
53EED_16625203_ChIP-ChIP_MESCs_Mouse1.41495732
54WT1_25993318_ChIP-Seq_PODOCYTE_Human1.41355623
55FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.41206656
56POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.41174792
57MYC_18555785_ChIP-Seq_MESCs_Mouse1.41012365
58EZH2_27294783_Chip-Seq_ESCs_Mouse1.40623219
59* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.39696526
60SUZ12_27294783_Chip-Seq_ESCs_Mouse1.39393932
61MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.38207995
62ISL1_27105846_Chip-Seq_CPCs_Mouse1.38065984
63SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.37884884
64RING1B_27294783_Chip-Seq_ESCs_Mouse1.37395107
65TP63_19390658_ChIP-ChIP_HaCaT_Human1.37017904
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35263856
67REST_21632747_ChIP-Seq_MESCs_Mouse1.34165421
68ZNF274_21170338_ChIP-Seq_K562_Hela1.33169194
69KDM2B_26808549_Chip-Seq_SUP-B15_Human1.32418325
70KDM2B_26808549_Chip-Seq_DND41_Human1.32133763
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.31994255
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30067144
73CBX2_27304074_Chip-Seq_ESCs_Mouse1.29974709
74BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.29711514
75WT1_19549856_ChIP-ChIP_CCG9911_Human1.29359876
76GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.28903760
77AR_19668381_ChIP-Seq_PC3_Human1.28095646
78TBX3_20139965_ChIP-Seq_MESCs_Mouse1.27936081
79FUS_26573619_Chip-Seq_HEK293_Human1.27706249
80TBX3_20139965_ChIP-Seq_ESCs_Mouse1.27299404
81E2F1_21310950_ChIP-Seq_MCF-7_Human1.24717309
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23137381
83RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22859516
84PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.22632293
85SOX2_21211035_ChIP-Seq_LN229_Gbm1.21951877
86ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.21833656
87CLOCK_20551151_ChIP-Seq_293T_Human1.21781587
88GATA1_26923725_Chip-Seq_HPCs_Mouse1.21575218
89POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.21101704
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.20499294
91SOX2_18555785_ChIP-Seq_MESCs_Mouse1.18351019
92FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.17100125
93GBX2_23144817_ChIP-Seq_PC3_Human1.16148121
94* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15605772
95DNAJC2_21179169_ChIP-ChIP_NT2_Human1.15114273
96MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14887553
97YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14692420
98TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14318998
99YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13674541
100* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13451220
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.12903630
102E2F7_22180533_ChIP-Seq_HELA_Human1.11926386
103RNF2_27304074_Chip-Seq_NSC_Mouse1.11858223
104KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.11429921
105NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.10956557
106TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09387761
107MYC_19079543_ChIP-ChIP_MESCs_Mouse1.09329087
108ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08598483
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08280970
110SMAD4_21799915_ChIP-Seq_A2780_Human1.07518961
111NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06404178
112SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06403759
113GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05599004
114KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.04831453
115KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.04831453
116KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.04831453
117CREB1_26743006_Chip-Seq_LNCaP_Human1.04661137
118CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04596971
119MYCN_18555785_ChIP-Seq_MESCs_Mouse1.04375308
120* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03803954
121HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03389263
122OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02241698
123NANOG_16153702_ChIP-ChIP_HESCs_Human1.02148473
124EP300_21415370_ChIP-Seq_HL-1_Mouse1.02111444
125STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.01699160
126KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01479367
127ARNT_22903824_ChIP-Seq_MCF-7_Human1.01283131
128ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00983145
129SMAD3_21741376_ChIP-Seq_ESCs_Human1.00720519
130TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.99856085
131POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.99365087
132CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.98645100
133POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98456081
134TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98456081
135TCF4_18268006_ChIP-ChIP_LS174T_Human0.97691739
136BMI1_23680149_ChIP-Seq_NPCS_Mouse0.96959736
137POU5F1_16518401_ChIP-PET_MESCs_Mouse0.96879682
138NANOG_21062744_ChIP-ChIP_HESCs_Human0.96562297
139PIAS1_25552417_ChIP-Seq_VCAP_Human0.96226163
140PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.96183394
141TP53_16413492_ChIP-PET_HCT116_Human0.95019633
142AHR_22903824_ChIP-Seq_MCF-7_Human0.94666631
143KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.94452484
144* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93613787
145BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.93191832
146* STAT3_23295773_ChIP-Seq_U87_Human0.92397047
147TAF15_26573619_Chip-Seq_HEK293_Human0.91524255
148ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.91157924
149AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90711340
150SMAD3_21741376_ChIP-Seq_EPCs_Human0.89035430
151PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.87381715
152KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.86353670
153CDX2_19796622_ChIP-Seq_MESCs_Mouse0.84649208

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.01819675
2MP0010234_abnormal_vibrissa_follicle3.85646492
3MP0003705_abnormal_hypodermis_morpholog2.73433564
4MP0000537_abnormal_urethra_morphology2.70287911
5MP0003122_maternal_imprinting2.58009122
6MP0003123_paternal_imprinting2.48533191
7MP0000566_synostosis2.44673184
8MP0003635_abnormal_synaptic_transmissio2.41178300
9MP0003880_abnormal_central_pattern2.38960617
10MP0005623_abnormal_meninges_morphology2.33263900
11MP0000569_abnormal_digit_pigmentation2.30803956
12MP0009780_abnormal_chondrocyte_physiolo2.16550383
13MP0003136_yellow_coat_color2.15348819
14MP0003121_genomic_imprinting2.03896740
15MP0002063_abnormal_learning/memory/cond1.96324092
16MP0003787_abnormal_imprinting1.96011465
17MP0004270_analgesia1.79829632
18MP0003941_abnormal_skin_development1.73649915
19MP0000778_abnormal_nervous_system1.66951481
20MP0002697_abnormal_eye_size1.62173819
21MP0004885_abnormal_endolymph1.59906386
22MP0005171_absent_coat_pigmentation1.59559517
23MP0004858_abnormal_nervous_system1.57897250
24MP0002938_white_spotting1.54653340
25MP0005423_abnormal_somatic_nervous1.54461314
26MP0008877_abnormal_DNA_methylation1.53755773
27MP0003385_abnormal_body_wall1.53570393
28MP0002653_abnormal_ependyma_morphology1.53338700
29MP0008932_abnormal_embryonic_tissue1.53008460
30MP0004957_abnormal_blastocyst_morpholog1.52447366
31MP0002064_seizures1.51014573
32MP0004272_abnormal_basement_membrane1.48056671
33MP0009745_abnormal_behavioral_response1.48043735
34MP0002009_preneoplasia1.42603694
35MP0003283_abnormal_digestive_organ1.42571659
36MP0003111_abnormal_nucleus_morphology1.41853547
37MP0000751_myopathy1.41086145
38MP0002909_abnormal_adrenal_gland1.40333305
39MP0001984_abnormal_olfaction1.39235307
40MP0009046_muscle_twitch1.38263797
41MP0004811_abnormal_neuron_physiology1.38123848
42MP0004233_abnormal_muscle_weight1.37974899
43MP0001293_anophthalmia1.35296629
44MP0008057_abnormal_DNA_replication1.34748434
45MP0001486_abnormal_startle_reflex1.34574885
46MP0010094_abnormal_chromosome_stability1.33237895
47MP0000955_abnormal_spinal_cord1.32656091
48MP0002822_catalepsy1.31565502
49MP0004130_abnormal_muscle_cell1.31564094
50MP0001968_abnormal_touch/_nociception1.30315471
51MP0003890_abnormal_embryonic-extraembry1.28969094
52MP0004133_heterotaxia1.27554047
53MP0003693_abnormal_embryo_hatching1.27383218
54MP0003115_abnormal_respiratory_system1.26722405
55MP0001286_abnormal_eye_development1.24779516
56MP0009053_abnormal_anal_canal1.24622560
57MP0003938_abnormal_ear_development1.24557674
58MP0002572_abnormal_emotion/affect_behav1.24107685
59MP0002152_abnormal_brain_morphology1.22238641
60MP0003861_abnormal_nervous_system1.21116448
61MP0002233_abnormal_nose_morphology1.21070714
62MP0005076_abnormal_cell_differentiation1.20166096
63MP0003077_abnormal_cell_cycle1.19156223
64MP0005187_abnormal_penis_morphology1.18401697
65MP0010352_gastrointestinal_tract_polyps1.18022053
66MP0000534_abnormal_ureter_morphology1.17739621
67MP0003755_abnormal_palate_morphology1.15767348
68MP0000733_abnormal_muscle_development1.13706524
69MP0003567_abnormal_fetal_cardiomyocyte1.13349365
70MP0000428_abnormal_craniofacial_morphol1.13069047
71MP0010678_abnormal_skin_adnexa1.10487809
72MP0000049_abnormal_middle_ear1.08408634
73MP0005380_embryogenesis_phenotype1.07717606
74MP0001672_abnormal_embryogenesis/_devel1.07717606
75MP0000579_abnormal_nail_morphology1.06885535
76MP0002184_abnormal_innervation1.06441079
77MP0002882_abnormal_neuron_morphology1.05495056
78MP0005248_abnormal_Harderian_gland1.04107710
79MP0001697_abnormal_embryo_size1.03785230
80MP0009250_abnormal_appendicular_skeleto1.03185829
81MP0002734_abnormal_mechanical_nocicepti1.03179223
82MP0002111_abnormal_tail_morphology1.03010321
83MP0001849_ear_inflammation0.99992803
84MP0001730_embryonic_growth_arrest0.99811578
85MP0002282_abnormal_trachea_morphology0.98568981
86MP0004185_abnormal_adipocyte_glucose0.98450057
87MP0001188_hyperpigmentation0.98303947
88MP0002116_abnormal_craniofacial_bone0.97970455
89MP0003045_fibrosis0.96160968
90MP0002088_abnormal_embryonic_growth/wei0.96124422
91MP0009672_abnormal_birth_weight0.95861919
92MP0002084_abnormal_developmental_patter0.95559284
93MP0000013_abnormal_adipose_tissue0.95334939
94MP0004197_abnormal_fetal_growth/weight/0.95162736
95MP0002272_abnormal_nervous_system0.95081818
96MP0003984_embryonic_growth_retardation0.94985871
97MP0000467_abnormal_esophagus_morphology0.93868752
98MP0003942_abnormal_urinary_system0.93506282
99MP0001348_abnormal_lacrimal_gland0.92749971
100MP0002092_abnormal_eye_morphology0.92580989
101MP0002733_abnormal_thermal_nociception0.92078652
102MP0002751_abnormal_autonomic_nervous0.91999900
103MP0000432_abnormal_head_morphology0.90815049
104MP0005386_behavior/neurological_phenoty0.90093041
105MP0004924_abnormal_behavior0.90093041
106MP0003119_abnormal_digestive_system0.89563421
107MP0002557_abnormal_social/conspecific_i0.88693371
108MP0004084_abnormal_cardiac_muscle0.88636493
109MP0004215_abnormal_myocardial_fiber0.86528934
110MP0002067_abnormal_sensory_capabilities0.85388566
111MP0010030_abnormal_orbit_morphology0.85281353
112MP0000350_abnormal_cell_proliferation0.83370598
113MP0008961_abnormal_basal_metabolism0.81301918
114MP0005394_taste/olfaction_phenotype0.81183811
115MP0005499_abnormal_olfactory_system0.81183811
116MP0003935_abnormal_craniofacial_develop0.80114545
117MP0002081_perinatal_lethality0.79962067
118MP0002234_abnormal_pharynx_morphology0.79550616
119MP0002080_prenatal_lethality0.78380637
120MP0003315_abnormal_perineum_morphology0.77839832
121MP0002066_abnormal_motor_capabilities/c0.77512386
122MP0002090_abnormal_vision0.77326149
123MP0010307_abnormal_tumor_latency0.77127073
124MP0003937_abnormal_limbs/digits/tail_de0.76476416
125MP0001299_abnormal_eye_distance/0.75710726
126MP0002114_abnormal_axial_skeleton0.75393210
127MP0000631_abnormal_neuroendocrine_gland0.75208769
128MP0009703_decreased_birth_body0.74785572
129MP0005167_abnormal_blood-brain_barrier0.74757503
130MP0001177_atelectasis0.74600549
131MP0001529_abnormal_vocalization0.74412359
132MP0001346_abnormal_lacrimal_gland0.74343480
133MP0008569_lethality_at_weaning0.74227798
134MP0000462_abnormal_digestive_system0.74114755
135MP0002249_abnormal_larynx_morphology0.73318766
136MP0002085_abnormal_embryonic_tissue0.73127964
137MP0006276_abnormal_autonomic_nervous0.72855364
138MP0006292_abnormal_olfactory_placode0.71840157
139MP0002752_abnormal_somatic_nervous0.71533858
140MP0003632_abnormal_nervous_system0.71266473
141MP0004087_abnormal_muscle_fiber0.71209135
142MP0002877_abnormal_melanocyte_morpholog0.71011023
143MP0000003_abnormal_adipose_tissue0.70748571
144MP0003633_abnormal_nervous_system0.70323189
145MP0003221_abnormal_cardiomyocyte_apopto0.70122284

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)3.87785235
2Cortical dysplasia (HP:0002539)3.22447615
3Myokymia (HP:0002411)2.90107711
4Hepatoblastoma (HP:0002884)2.83762046
5Insidious onset (HP:0003587)2.80688702
6Termporal pattern (HP:0011008)2.80688702
7Resting tremor (HP:0002322)2.78334050
8Hyperacusis (HP:0010780)2.77893277
9Asymmetry of the thorax (HP:0001555)2.77590983
10Pointed chin (HP:0000307)2.63709339
11Renovascular hypertension (HP:0100817)2.61233414
12Macroorchidism (HP:0000053)2.59235620
13Astrocytoma (HP:0009592)2.54879489
14Abnormality of the astrocytes (HP:0100707)2.54879489
15Lymphangioma (HP:0100764)2.52380606
16Elfin facies (HP:0004428)2.51831960
17Insomnia (HP:0100785)2.51148121
18Subacute progressive viral hepatitis (HP:0006572)2.47552842
19Action tremor (HP:0002345)2.46108390
20Renal duplication (HP:0000075)2.45253965
21Neoplasm of the heart (HP:0100544)2.39756307
22Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.38810631
23Short 4th metacarpal (HP:0010044)2.38810631
24Buphthalmos (HP:0000557)2.36555967
25Papilledema (HP:0001085)2.34231639
26Overriding aorta (HP:0002623)2.32807227
27Hamartoma of the eye (HP:0010568)2.32049474
28Visual hallucinations (HP:0002367)2.30910826
29Ependymoma (HP:0002888)2.29049986
30Urinary urgency (HP:0000012)2.26976829
31Enlarged penis (HP:0000040)2.26573612
32Hypopigmentation of the fundus (HP:0007894)2.25968123
33High anterior hairline (HP:0009890)2.21284659
34Impaired vibration sensation in the lower limbs (HP:0002166)2.20868945
35Fibrous tissue neoplasm (HP:0012316)2.20520196
36Ankyloglossia (HP:0010296)2.19426722
37Megalencephaly (HP:0001355)2.18308000
38Fibroma (HP:0010614)2.18190470
39Shallow orbits (HP:0000586)2.17611877
40Vertebral arch anomaly (HP:0008438)2.15973576
41Heterotopia (HP:0002282)2.15808255
42Abnormality of the diencephalon (HP:0010662)2.15450631
43Abnormality of the 4th metacarpal (HP:0010012)2.15297575
44Pseudobulbar signs (HP:0002200)2.14793674
45Broad metatarsal (HP:0001783)2.13481417
46Depression (HP:0000716)2.12583600
47Focal motor seizures (HP:0011153)2.10571672
48Focal seizures (HP:0007359)2.02609223
49Bowel diverticulosis (HP:0005222)2.02338155
50Papillary thyroid carcinoma (HP:0002895)2.00577084
51Obsessive-compulsive behavior (HP:0000722)1.98006965
52Neoplasm of the peripheral nervous system (HP:0100007)1.97419377
53Cerebral aneurysm (HP:0004944)1.95778030
54Anophthalmia (HP:0000528)1.94984954
55Mitral valve prolapse (HP:0001634)1.94721917
56Coronal craniosynostosis (HP:0004440)1.94574722
57Hyperthyroidism (HP:0000836)1.92317433
58Cutaneous finger syndactyly (HP:0010554)1.91539887
59Aplasia involving bones of the extremities (HP:0009825)1.91436434
60Aplasia involving bones of the upper limbs (HP:0009823)1.91436434
61Aplasia of the phalanges of the hand (HP:0009802)1.91436434
62Abnormal lung lobation (HP:0002101)1.91402953
63Limb dystonia (HP:0002451)1.90376695
64Bladder diverticulum (HP:0000015)1.89858161
65Cutaneous syndactyly (HP:0012725)1.89680909
66Abnormality of the labia minora (HP:0012880)1.89536156
67Aplasia/Hypoplasia of the sternum (HP:0006714)1.88250153
68Hemangiomatosis (HP:0007461)1.87878600
69Preaxial foot polydactyly (HP:0001841)1.87787191
70Intention tremor (HP:0002080)1.87782536
71Striae distensae (HP:0001065)1.86666727
72Poor eye contact (HP:0000817)1.86081365
73Flat cornea (HP:0007720)1.85954129
74Nephroblastoma (Wilms tumor) (HP:0002667)1.85543706
75Subcapsular cataract (HP:0000523)1.84099231
76Missing ribs (HP:0000921)1.83205928
77Arnold-Chiari malformation (HP:0002308)1.83000186
78Impaired social interactions (HP:0000735)1.82965625
79Abnormal social behavior (HP:0012433)1.82965625
80Increased nuchal translucency (HP:0010880)1.82855239
81Posterior subcapsular cataract (HP:0007787)1.81708201
82Visceral angiomatosis (HP:0100761)1.81305119
83Myelomeningocele (HP:0002475)1.81235059
84Supranuclear gaze palsy (HP:0000605)1.80846189
85Glioma (HP:0009733)1.80831139
86Embryonal renal neoplasm (HP:0011794)1.79994571
87Neoplasm of striated muscle (HP:0009728)1.78156393
88Urinary bladder sphincter dysfunction (HP:0002839)1.78145313
89Overlapping toe (HP:0001845)1.78051570
90Colon cancer (HP:0003003)1.77420235
91Broad distal phalanx of finger (HP:0009836)1.77156464
92Adenoma sebaceum (HP:0009720)1.77065309
93Angiofibromas (HP:0010615)1.77065309
94Hypoventilation (HP:0002791)1.77064632
95Postural tremor (HP:0002174)1.76653331
96Medulloblastoma (HP:0002885)1.76444828
97Drooling (HP:0002307)1.76369065
98Chromosomal breakage induced by crosslinking agents (HP:0003221)1.76315117
99Bronchomalacia (HP:0002780)1.75717599
100Hamartoma (HP:0010566)1.74952642
101Lower limb asymmetry (HP:0100559)1.74369756
102Volvulus (HP:0002580)1.74286234
103Abnormality of the ischium (HP:0003174)1.74243886
104Dysdiadochokinesis (HP:0002075)1.73993737
105Abnormality of chromosome segregation (HP:0002916)1.73818503
106Annular pancreas (HP:0001734)1.72886348
107Generalized hypotonia (HP:0001290)1.70770180
108Midline defect of the nose (HP:0004122)1.70303760
109Omphalocele (HP:0001539)1.70269845
110Hand muscle atrophy (HP:0009130)1.70135165
111Abnormality of oral frenula (HP:0000190)1.69612205
112Shoulder girdle muscle weakness (HP:0003547)1.69147623
113Deviation of the hallux (HP:0010051)1.68432338
114Ankle clonus (HP:0011448)1.68409159
115Dysmetric saccades (HP:0000641)1.68359291
116Upper limb amyotrophy (HP:0009129)1.67520964
117Distal upper limb amyotrophy (HP:0007149)1.67520964
118Progressive cerebellar ataxia (HP:0002073)1.67384413
119Hallux valgus (HP:0001822)1.67377945
120Chromsome breakage (HP:0040012)1.67334374
121Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.66921916
122Achilles tendon contracture (HP:0001771)1.66671877
123Abnormality of ocular smooth pursuit (HP:0000617)1.65525754
124Choanal stenosis (HP:0000452)1.65395040
125Abnormality of the pubic bones (HP:0003172)1.65097163
126Truncal obesity (HP:0001956)1.65059694
127Hammertoe (HP:0001765)1.62662236
128Testicular neoplasm (HP:0010788)1.62516362
129Duplication of thumb phalanx (HP:0009942)1.62056114
130Hypoplastic ischia (HP:0003175)1.61827027
131Abnormality of the corticospinal tract (HP:0002492)1.61730049
132Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.61607228
133Bilateral microphthalmos (HP:0007633)1.61239300
134Long toe (HP:0010511)1.60951791
135Hemiplegia (HP:0002301)1.60392161
136Bicornuate uterus (HP:0000813)1.59877800
137Increased variability in muscle fiber diameter (HP:0003557)1.59806995
138Intellectual disability, profound (HP:0002187)1.59796805
139Rectal prolapse (HP:0002035)1.59712707
140Neoplasm of the adrenal cortex (HP:0100641)1.58911875
141Turricephaly (HP:0000262)1.58889905
142Acute lymphatic leukemia (HP:0006721)1.57784407
143Abnormal number of incisors (HP:0011064)1.56972911
144Attention deficit hyperactivity disorder (HP:0007018)1.55603731
145Broad thumb (HP:0011304)1.53209973
146Gastrointestinal carcinoma (HP:0002672)1.52796489
147Malignant gastrointestinal tract tumors (HP:0006749)1.52796489
148Trigonocephaly (HP:0000243)1.51699390
149Septo-optic dysplasia (HP:0100842)1.49896916
150Broad phalanges of the hand (HP:0009768)1.49850353
151Abnormal pancreas size (HP:0012094)1.49141645
152Pheochromocytoma (HP:0002666)1.49006842
153Broad finger (HP:0001500)1.48370639
154Excessive salivation (HP:0003781)1.47580373
155Atonic seizures (HP:0010819)1.46890098
156Abnormality of dentin (HP:0010299)1.46779544
157Bifid tongue (HP:0010297)1.44794214
158Hypoplastic labia majora (HP:0000059)1.44720530
159Cheekbone underdevelopment (HP:0010669)1.44656886
160Tracheomalacia (HP:0002779)1.44417826
161Labial hypoplasia (HP:0000066)1.44072135
162Abnormality of the antihelix (HP:0009738)1.42706782
163Morphological abnormality of the inner ear (HP:0011390)1.42619429
164Thin ribs (HP:0000883)1.42305699
165Micropenis (HP:0000054)1.41179287
166Abnormality of the septum pellucidum (HP:0007375)1.40676451
167Abnormality of cochlea (HP:0000375)1.40271139
168Aqueductal stenosis (HP:0002410)1.40160304
169Vitreoretinal degeneration (HP:0000655)1.39948128
170Spina bifida occulta (HP:0003298)1.38526742
171Neoplasm of the oral cavity (HP:0100649)1.38410907

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK13.79656333
2PKN23.00716474
3MAP3K43.00293762
4TRIB32.63725908
5MAP3K92.59676069
6CASK2.53461210
7TTK2.41553316
8NTRK32.34435172
9KSR22.17355380
10PDK32.04639166
11PDK42.04639166
12EEF2K2.02461401
13TNIK1.94685649
14PRKD31.90563098
15MKNK11.78511689
16TAF11.78378188
17TSSK61.77331361
18MINK11.77190908
19MAP2K41.74979470
20WEE11.71365995
21PAK61.68556107
22ICK1.64969168
23RET1.60600164
24TYRO31.59866759
25LATS11.59366042
26CDK121.56285953
27KSR11.55938728
28SCYL21.52199362
29EPHA41.47030352
30LMTK21.46532105
31BUB11.44977807
32PASK1.44242970
33STK38L1.42322488
34MAPKAPK51.40273543
35FGFR21.38750569
36MAP3K21.38718415
37MKNK21.37993817
38MARK11.35391580
39PDGFRA1.27921696
40LATS21.27409432
41ALK1.26470259
42CAMK1G1.25611903
43PNCK1.25343719
44DAPK21.25042441
45NTRK11.23869269
46TLK11.23845494
47FER1.20513663
48CAMKK11.19984937
49NTRK21.19599574
50BRD41.18754315
51SMG11.16875505
52NEK21.14058918
53BCR1.13743955
54PTK61.11827340
55DYRK21.09044362
56SRPK11.07467458
57CDC71.06680780
58CDK191.05225864
59CDK61.04386910
60CHEK21.03104264
61WNK11.02735463
62MAP2K71.02347537
63SIK21.01101187
64PLK30.99944592
65DDR20.93838294
66CDK50.91969858
67STK110.90433783
68RIPK10.90050960
69LRRK20.88309345
70PLK40.88214627
71MAP3K60.87252648
72MAP3K100.85314164
73UHMK10.84395170
74TGFBR10.77731555
75BRSK10.75356841
76FGFR10.75232484
77ATR0.71542104
78PLK10.71330102
79STK380.71262255
80SIK10.70764099
81RPS6KA20.70637332
82ERBB20.70425326
83PDK20.69588865
84PINK10.69476522
85PTK2B0.69070549
86CAMK1D0.68333782
87CAMK2B0.68178938
88ZAK0.66538111
89CHEK10.64489368
90BRAF0.63456218
91DYRK30.62106526
92BRSK20.60565256
93CDK10.60546056
94PAK30.59789255
95ATM0.59000047
96EPHB20.58828157
97CSNK1G20.58790236
98MAP3K70.58717984
99CDK140.58354387
100FGFR30.58182739
101STK30.57676079
102CSNK1E0.57489684
103CDK150.57161993
104PLK20.56489860
105MAP2K10.56238912
106BMX0.55633905
107CDK20.54880569
108TTN0.54834567
109PAK20.54547887
110MET0.54000629
111CDK180.53069731
112MTOR0.53068749
113SGK30.51341612
114PRKCH0.51248401
115CDK70.49004877
116RPS6KB20.48210346
117CDK11A0.47786291
118PAK40.46534652
119PDGFRB0.46489851
120CSNK1A1L0.46245033
121CSNK1D0.46080143
122CSNK1G10.45594553
123PTK20.44854368
124DMPK0.44827903
125MAPK100.44571375
126MELK0.44442742
127RPS6KA30.43783234
128EIF2AK20.43765840
129ROCK20.43422300
130PRKCG0.41773245
131SGK4940.41666132
132SGK2230.41666132
133PHKG10.41212312
134PHKG20.41212312
135GSK3B0.40440522
136CDK90.39975879
137RAF10.39959995
138SGK10.39928264
139AURKB0.39634194
140FRK0.39066216
141PDK10.38936950
142SGK20.38006241
143DAPK10.36123022
144MAPK130.34071285
145PRKDC0.33865413

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.09245926
2Long-term potentiation_Homo sapiens_hsa047201.97326215
3Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77673447
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.76544523
5Cell cycle_Homo sapiens_hsa041101.72499117
6Circadian entrainment_Homo sapiens_hsa047131.68312222
7Nicotine addiction_Homo sapiens_hsa050331.65915173
8Glioma_Homo sapiens_hsa052141.62696579
9Dopaminergic synapse_Homo sapiens_hsa047281.60055471
10GABAergic synapse_Homo sapiens_hsa047271.57244143
11Selenocompound metabolism_Homo sapiens_hsa004501.56828031
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.54901843
13Olfactory transduction_Homo sapiens_hsa047401.51097811
14Oocyte meiosis_Homo sapiens_hsa041141.49253944
15Renin secretion_Homo sapiens_hsa049241.48613310
16Estrogen signaling pathway_Homo sapiens_hsa049151.48056594
17mTOR signaling pathway_Homo sapiens_hsa041501.46611393
18Synaptic vesicle cycle_Homo sapiens_hsa047211.45356862
19Dorso-ventral axis formation_Homo sapiens_hsa043201.44960999
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43064846
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.41788595
22Amphetamine addiction_Homo sapiens_hsa050311.41242777
23Central carbon metabolism in cancer_Homo sapiens_hsa052301.38655985
24DNA replication_Homo sapiens_hsa030301.38378934
25Melanogenesis_Homo sapiens_hsa049161.37113665
26Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.37036412
27Glutamatergic synapse_Homo sapiens_hsa047241.36144014
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.35409988
29Gastric acid secretion_Homo sapiens_hsa049711.34941239
30Endometrial cancer_Homo sapiens_hsa052131.32603483
31Morphine addiction_Homo sapiens_hsa050321.31852586
32Axon guidance_Homo sapiens_hsa043601.29441529
33Cholinergic synapse_Homo sapiens_hsa047251.28755816
34Salivary secretion_Homo sapiens_hsa049701.28572152
35Gap junction_Homo sapiens_hsa045401.27434145
36Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.27332375
37Long-term depression_Homo sapiens_hsa047301.26242840
38Oxytocin signaling pathway_Homo sapiens_hsa049211.25466640
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.24320563
40Mismatch repair_Homo sapiens_hsa034301.24194629
41Type II diabetes mellitus_Homo sapiens_hsa049301.21938936
42GnRH signaling pathway_Homo sapiens_hsa049121.21368390
43Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.20920954
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20199101
45Biosynthesis of amino acids_Homo sapiens_hsa012301.19041295
46RNA transport_Homo sapiens_hsa030131.18576195
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.15788022
48Fatty acid biosynthesis_Homo sapiens_hsa000611.10407575
49VEGF signaling pathway_Homo sapiens_hsa043701.07685567
50Thyroid hormone signaling pathway_Homo sapiens_hsa049191.07236435
51Non-small cell lung cancer_Homo sapiens_hsa052231.07208753
52Aldosterone synthesis and secretion_Homo sapiens_hsa049251.06174918
53Glucagon signaling pathway_Homo sapiens_hsa049221.06021768
54Hippo signaling pathway_Homo sapiens_hsa043901.05887280
55ErbB signaling pathway_Homo sapiens_hsa040121.05645224
56Insulin signaling pathway_Homo sapiens_hsa049101.05531884
57Steroid biosynthesis_Homo sapiens_hsa001001.05117045
58Spliceosome_Homo sapiens_hsa030401.02420865
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.02008733
60Non-homologous end-joining_Homo sapiens_hsa034500.99765679
61Colorectal cancer_Homo sapiens_hsa052100.99507626
62Proteoglycans in cancer_Homo sapiens_hsa052050.97776178
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.96224698
64Basal transcription factors_Homo sapiens_hsa030220.95683372
65Hedgehog signaling pathway_Homo sapiens_hsa043400.94869186
66Renal cell carcinoma_Homo sapiens_hsa052110.94761944
67Insulin secretion_Homo sapiens_hsa049110.93461206
68Chronic myeloid leukemia_Homo sapiens_hsa052200.92069860
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91821045
70One carbon pool by folate_Homo sapiens_hsa006700.91772188
71TGF-beta signaling pathway_Homo sapiens_hsa043500.91128120
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.91050987
73Cocaine addiction_Homo sapiens_hsa050300.90935627
74Basal cell carcinoma_Homo sapiens_hsa052170.90811738
75Alcoholism_Homo sapiens_hsa050340.90668654
76AMPK signaling pathway_Homo sapiens_hsa041520.89753996
77Tight junction_Homo sapiens_hsa045300.89495026
78Focal adhesion_Homo sapiens_hsa045100.88933316
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88537100
80cAMP signaling pathway_Homo sapiens_hsa040240.87497070
81Base excision repair_Homo sapiens_hsa034100.85739420
82Arginine biosynthesis_Homo sapiens_hsa002200.85706286
83Thyroid hormone synthesis_Homo sapiens_hsa049180.84772670
84Phosphatidylinositol signaling system_Homo sapiens_hsa040700.84379286
85Thyroid cancer_Homo sapiens_hsa052160.84210333
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.83683984
87Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82779263
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82501095
89Dilated cardiomyopathy_Homo sapiens_hsa054140.82260899
90Prostate cancer_Homo sapiens_hsa052150.82110430
91Wnt signaling pathway_Homo sapiens_hsa043100.81751148
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.81334864
93Carbon metabolism_Homo sapiens_hsa012000.80242834
94Pyruvate metabolism_Homo sapiens_hsa006200.78851336
95Nucleotide excision repair_Homo sapiens_hsa034200.78575750
96Melanoma_Homo sapiens_hsa052180.77814064
97Lysine degradation_Homo sapiens_hsa003100.77344959
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77095051
99Adherens junction_Homo sapiens_hsa045200.76067051
100Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76041391
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.74867291
102Cysteine and methionine metabolism_Homo sapiens_hsa002700.74786355
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.74263615
104Butanoate metabolism_Homo sapiens_hsa006500.74023623
105Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72460505
106Fanconi anemia pathway_Homo sapiens_hsa034600.71869107
107Calcium signaling pathway_Homo sapiens_hsa040200.71832496
108Rap1 signaling pathway_Homo sapiens_hsa040150.71495910
109Bladder cancer_Homo sapiens_hsa052190.69758514
110Bile secretion_Homo sapiens_hsa049760.69615901
111Notch signaling pathway_Homo sapiens_hsa043300.68484624
112Choline metabolism in cancer_Homo sapiens_hsa052310.68420903
113MicroRNAs in cancer_Homo sapiens_hsa052060.67388738
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.67120498
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.66655987
116Fatty acid metabolism_Homo sapiens_hsa012120.65673015
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65174258
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.64650436
119Insulin resistance_Homo sapiens_hsa049310.64224145
120ECM-receptor interaction_Homo sapiens_hsa045120.63973331
121Taste transduction_Homo sapiens_hsa047420.61575268
122mRNA surveillance pathway_Homo sapiens_hsa030150.60625357
123Phototransduction_Homo sapiens_hsa047440.59081243
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58933394
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58511118
126Pancreatic cancer_Homo sapiens_hsa052120.58494216
127Serotonergic synapse_Homo sapiens_hsa047260.57248402
128Pathways in cancer_Homo sapiens_hsa052000.54794128
129MAPK signaling pathway_Homo sapiens_hsa040100.54787660
130Endocytosis_Homo sapiens_hsa041440.54497267

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