COMMD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.13012460
2ribosomal small subunit biogenesis (GO:0042274)6.07324947
3ribosomal small subunit assembly (GO:0000028)6.05812547
4translational termination (GO:0006415)5.95823854
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.83084173
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.50701079
7cotranslational protein targeting to membrane (GO:0006613)5.48310590
8ATP synthesis coupled proton transport (GO:0015986)5.47164634
9energy coupled proton transport, down electrochemical gradient (GO:0015985)5.47164634
10proteasome assembly (GO:0043248)5.43008529
11maturation of SSU-rRNA (GO:0030490)5.41049042
12protein targeting to ER (GO:0045047)5.40870799
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.14154960
14protein localization to endoplasmic reticulum (GO:0070972)5.13220188
15translational elongation (GO:0006414)5.10896689
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.85692581
17DNA deamination (GO:0045006)4.77209369
18ribosomal large subunit biogenesis (GO:0042273)4.76515656
19viral life cycle (GO:0019058)4.67520897
20cellular protein complex disassembly (GO:0043624)4.66828810
21translational initiation (GO:0006413)4.51086291
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.40046156
23respiratory electron transport chain (GO:0022904)4.37566309
24platelet dense granule organization (GO:0060155)4.32504788
25translation (GO:0006412)4.27151741
26mitochondrial respiratory chain complex I assembly (GO:0032981)4.26451068
27NADH dehydrogenase complex assembly (GO:0010257)4.26451068
28mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.26451068
29electron transport chain (GO:0022900)4.25789665
30establishment of integrated proviral latency (GO:0075713)4.13463685
31termination of RNA polymerase III transcription (GO:0006386)4.11673496
32transcription elongation from RNA polymerase III promoter (GO:0006385)4.11673496
33negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.05330455
34protein complex biogenesis (GO:0070271)4.04469646
35respiratory chain complex IV assembly (GO:0008535)4.04247219
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.93732261
37protein complex disassembly (GO:0043241)3.93690291
38protein neddylation (GO:0045116)3.89680208
39cytochrome complex assembly (GO:0017004)3.88821827
40regulation of mitochondrial translation (GO:0070129)3.85140084
41mitochondrial respiratory chain complex assembly (GO:0033108)3.84616542
42telomere maintenance via semi-conservative replication (GO:0032201)3.79797642
43negative regulation of ligase activity (GO:0051352)3.76487001
44negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.76487001
45chaperone-mediated protein transport (GO:0072321)3.75938425
46macromolecular complex disassembly (GO:0032984)3.75846922
47regulation of cellular amino acid metabolic process (GO:0006521)3.75716895
48positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.72372610
49cullin deneddylation (GO:0010388)3.70330069
50ribonucleoprotein complex biogenesis (GO:0022613)3.70307438
51GTP biosynthetic process (GO:0006183)3.69323612
52establishment of protein localization to mitochondrial membrane (GO:0090151)3.66284444
53regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.65773800
54L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.64535758
55hydrogen ion transmembrane transport (GO:1902600)3.61054429
56establishment of viral latency (GO:0019043)3.59965724
57DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.58509833
58protein deneddylation (GO:0000338)3.58053744
59anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.56872598
60CENP-A containing nucleosome assembly (GO:0034080)3.55323339
61spliceosomal snRNP assembly (GO:0000387)3.55000514
62RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.54598741
63tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.54598741
64protein targeting to membrane (GO:0006612)3.53503857
65intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.53116949
66signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.53116949
67cellular component biogenesis (GO:0044085)3.52102251
68antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.51837272
69DNA strand elongation involved in DNA replication (GO:0006271)3.51696447
70signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50045102
71signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50045102
72signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50045102
73ATP biosynthetic process (GO:0006754)3.49380284
74purine nucleoside triphosphate biosynthetic process (GO:0009145)3.46193969
75inner mitochondrial membrane organization (GO:0007007)3.44686343
767-methylguanosine mRNA capping (GO:0006370)3.43868889
77chromatin remodeling at centromere (GO:0031055)3.42070422
78DNA strand elongation (GO:0022616)3.41396652
79purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.40918838
80signal transduction involved in DNA integrity checkpoint (GO:0072401)3.40679007
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.40679007
82protein targeting to mitochondrion (GO:0006626)3.37998701
83RNA capping (GO:0036260)3.37284033
847-methylguanosine RNA capping (GO:0009452)3.37284033
85signal transduction involved in cell cycle checkpoint (GO:0072395)3.35990182
86proton transport (GO:0015992)3.33732834
87nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32753983
88peptidyl-histidine modification (GO:0018202)3.32555059
89rRNA modification (GO:0000154)3.32032036
90exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.31986406
91establishment of protein localization to mitochondrion (GO:0072655)3.31436796
92spliceosomal complex assembly (GO:0000245)3.31085881
93telomere maintenance via recombination (GO:0000722)3.30450643
94nuclear-transcribed mRNA catabolic process (GO:0000956)3.30432567
95rRNA processing (GO:0006364)3.28312682
96hydrogen transport (GO:0006818)3.27491675
97antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.27362524
98transcription-coupled nucleotide-excision repair (GO:0006283)3.26813388
99intracellular protein transmembrane import (GO:0044743)3.26067192
100oxidative phosphorylation (GO:0006119)3.23810207
101UTP biosynthetic process (GO:0006228)3.22404577
102pseudouridine synthesis (GO:0001522)3.19560655
103mannosylation (GO:0097502)3.17198256
104water-soluble vitamin biosynthetic process (GO:0042364)3.16103295
105positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.15639324
106protein-cofactor linkage (GO:0018065)3.14460825
107iron-sulfur cluster assembly (GO:0016226)3.14443674
108metallo-sulfur cluster assembly (GO:0031163)3.14443674
109mRNA catabolic process (GO:0006402)3.13992584
110rRNA metabolic process (GO:0016072)3.12183304
111guanosine-containing compound biosynthetic process (GO:1901070)3.12026631
112viral mRNA export from host cell nucleus (GO:0046784)3.10677205
113positive regulation of ligase activity (GO:0051351)3.10353001
114sequestering of actin monomers (GO:0042989)3.09317322
115protein localization to mitochondrion (GO:0070585)3.08532072
116deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.08377331
117nucleotide-excision repair, DNA gap filling (GO:0006297)3.05598847
118base-excision repair, AP site formation (GO:0006285)3.01529501
119kinetochore assembly (GO:0051382)3.00843343
120ribonucleoside triphosphate biosynthetic process (GO:0009201)2.94985570
121pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.90844238
122regulation of mitotic spindle checkpoint (GO:1903504)2.87926268
123regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.87926268
124DNA damage response, detection of DNA damage (GO:0042769)2.80405881
125DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.77518946
126mitochondrial transport (GO:0006839)2.76766157

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.83159724
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.50031840
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.33307987
4MYC_18555785_ChIP-Seq_MESCs_Mouse4.32855518
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.15257224
6E2F7_22180533_ChIP-Seq_HELA_Human4.03146164
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.89903034
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.67482116
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.59372510
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.53552343
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46772741
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.36500497
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.23805332
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.11156970
15MYC_18358816_ChIP-ChIP_MESCs_Mouse3.10205650
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.05436532
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.96281479
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.91690414
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.75617906
20MYC_19079543_ChIP-ChIP_MESCs_Mouse2.72447926
21XRN2_22483619_ChIP-Seq_HELA_Human2.51360069
22DCP1A_22483619_ChIP-Seq_HELA_Human2.49863573
23VDR_23849224_ChIP-Seq_CD4+_Human2.49167805
24E2F4_17652178_ChIP-ChIP_JURKAT_Human2.48181969
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.41501567
26SRF_21415370_ChIP-Seq_HL-1_Mouse2.38090271
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.37526896
28ZNF274_21170338_ChIP-Seq_K562_Hela2.37458914
29ELK1_19687146_ChIP-ChIP_HELA_Human2.16213733
30* TTF2_22483619_ChIP-Seq_HELA_Human2.15107019
31* FOXP3_21729870_ChIP-Seq_TREG_Human2.14249900
32* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13942917
33THAP11_20581084_ChIP-Seq_MESCs_Mouse2.10427723
34PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.06980927
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.01211798
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.91933151
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.87532742
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.87175605
39GABP_19822575_ChIP-Seq_HepG2_Human1.85533070
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.85259193
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82637828
42FLI1_27457419_Chip-Seq_LIVER_Mouse1.77808565
43CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.69586821
44* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68660128
45EWS_26573619_Chip-Seq_HEK293_Human1.66192843
46FOXM1_23109430_ChIP-Seq_U2OS_Human1.63771753
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59989814
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54775531
49IGF1R_20145208_ChIP-Seq_DFB_Human1.53892709
50ELK1_22589737_ChIP-Seq_MCF10A_Human1.52815988
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.46809128
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43715281
53POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.42804564
54FUS_26573619_Chip-Seq_HEK293_Human1.40390091
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39296505
56TP53_22573176_ChIP-Seq_HFKS_Human1.38982907
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.36151894
58MYCN_18555785_ChIP-Seq_MESCs_Mouse1.35495256
59MYC_18940864_ChIP-ChIP_HL60_Human1.34415968
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34191879
61EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32794263
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.32062901
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31494100
64POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.30820252
65YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30144585
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.29534806
67* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.29508103
68AR_21909140_ChIP-Seq_LNCAP_Human1.28920815
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.27939885
70CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.25165055
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24028006
72* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22223993
73POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20684384
74AR_20517297_ChIP-Seq_VCAP_Human1.16643823
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15216553
76* P300_19829295_ChIP-Seq_ESCs_Human1.14520266
77FOXA1_25329375_ChIP-Seq_VCAP_Human1.14164046
78FOXA1_27270436_Chip-Seq_PROSTATE_Human1.14164046
79IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.13926971
80GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13747616
81ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13211399
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12310921
83BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11652889
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.11213593
85PADI4_21655091_ChIP-ChIP_MCF-7_Human1.09170438
86CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.06596394
87NANOG_19829295_ChIP-Seq_ESCs_Human1.06445228
88SOX2_19829295_ChIP-Seq_ESCs_Human1.06445228
89SOX17_20123909_ChIP-Seq_XEN_Mouse1.06135935
90CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05425156
91HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.03660673
92IRF1_19129219_ChIP-ChIP_H3396_Human1.00519403
93CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00517811
94SOX2_16153702_ChIP-ChIP_HESCs_Human1.00217716
95CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00135600
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99968110
97* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.98766012
98SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97373469
99E2F1_21310950_ChIP-Seq_MCF-7_Human0.92487780
100SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92399610
101ERG_20517297_ChIP-Seq_VCAP_Human0.92373479
102CIITA_25753668_ChIP-Seq_RAJI_Human0.92154358
103GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92045563
104E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.90296125
105TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.88820061
106FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.88769990
107KDM5A_27292631_Chip-Seq_BREAST_Human0.88724099
108VDR_22108803_ChIP-Seq_LS180_Human0.86914532
109* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86799289
110HTT_18923047_ChIP-ChIP_STHdh_Human0.86444626
111NCOR_22424771_ChIP-Seq_293T_Human0.86200970
112FOXA1_21572438_ChIP-Seq_LNCaP_Human0.85393145
113EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84640810
114SOX2_18692474_ChIP-Seq_MEFs_Mouse0.84342984
115NFE2_27457419_Chip-Seq_LIVER_Mouse0.82959034
116TAF15_26573619_Chip-Seq_HEK293_Human0.82604586
117GATA3_21878914_ChIP-Seq_MCF-7_Human0.82326554
118CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.81501343
119AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80526113
120* YY1_22570637_ChIP-Seq_MALME-3M_Human0.80130835
121ER_23166858_ChIP-Seq_MCF-7_Human0.78828910
122SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78549086
123* CBP_20019798_ChIP-Seq_JUKART_Human0.78228194
124OCT4_18692474_ChIP-Seq_MEFs_Mouse0.70630712
125* PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.69029348
126SRY_22984422_ChIP-ChIP_TESTIS_Rat0.68756033
127TBX5_21415370_ChIP-Seq_HL-1_Mouse0.68034717
128GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.67188756
129FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65131257
130KLF4_18555785_ChIP-Seq_MESCs_Mouse0.65023017
131KAP1_22055183_ChIP-Seq_ESCs_Mouse0.63691571
132STAT3_1855785_ChIP-Seq_MESCs_Mouse0.62709811
133SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.62512518
134SPI1_23547873_ChIP-Seq_NB4_Human0.61958370
135EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.61862239
136TFEB_21752829_ChIP-Seq_HELA_Human0.60806259
137BP1_19119308_ChIP-ChIP_Hs578T_Human0.60567211
138NANOG_16153702_ChIP-ChIP_HESCs_Human0.60530067

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.93223905
2MP0003693_abnormal_embryo_hatching4.61065064
3MP0003806_abnormal_nucleotide_metabolis3.42489648
4MP0004957_abnormal_blastocyst_morpholog3.41272357
5MP0010094_abnormal_chromosome_stability2.70465064
6MP0003186_abnormal_redox_activity2.69744733
7MP0003011_delayed_dark_adaptation2.69320223
8MP0003136_yellow_coat_color2.68116927
9MP0008932_abnormal_embryonic_tissue2.61552606
10MP0008058_abnormal_DNA_repair2.53773516
11MP0003077_abnormal_cell_cycle2.45196080
12MP0001529_abnormal_vocalization2.41804840
13MP0001986_abnormal_taste_sensitivity2.24354166
14MP0006036_abnormal_mitochondrial_physio2.20655697
15MP0010030_abnormal_orbit_morphology2.08714452
16MP0003111_abnormal_nucleus_morphology2.02095079
17MP0003315_abnormal_perineum_morphology2.00421556
18MP0002102_abnormal_ear_morphology2.00021577
19MP0008057_abnormal_DNA_replication1.96575409
20MP0003718_maternal_effect1.88261434
21MP0009697_abnormal_copulation1.84273120
22MP0000566_synostosis1.83620253
23MP0004381_abnormal_hair_follicle1.78978909
24MP0005645_abnormal_hypothalamus_physiol1.76404969
25MP0000372_irregular_coat_pigmentation1.70591803
26MP0008875_abnormal_xenobiotic_pharmacok1.70551607
27MP0002736_abnormal_nociception_after1.70397492
28MP0006292_abnormal_olfactory_placode1.64465771
29MP0003786_premature_aging1.63988964
30MP0001485_abnormal_pinna_reflex1.62479315
31MP0003950_abnormal_plasma_membrane1.60654733
32MP0002163_abnormal_gland_morphology1.60149962
33MP0002938_white_spotting1.59822299
34MP0004133_heterotaxia1.58213618
35MP0002638_abnormal_pupillary_reflex1.56992025
36MP0005671_abnormal_response_to1.55320388
37MP0008872_abnormal_physiological_respon1.55001849
38MP0008007_abnormal_cellular_replicative1.54266333
39MP0001764_abnormal_homeostasis1.44620273
40MP0006072_abnormal_retinal_apoptosis1.43452740
41MP0006035_abnormal_mitochondrial_morpho1.40014058
42MP0001968_abnormal_touch/_nociception1.39057108
43MP0004147_increased_porphyrin_level1.36768508
44MP0002132_abnormal_respiratory_system1.34363791
45MP0005253_abnormal_eye_physiology1.34324468
46MP0001905_abnormal_dopamine_level1.25354779
47MP0000749_muscle_degeneration1.24902726
48MP0001984_abnormal_olfaction1.24078437
49MP0005174_abnormal_tail_pigmentation1.22754529
50MP0002254_reproductive_system_inflammat1.21104875
51MP0005451_abnormal_body_composition1.20365226
52MP0005410_abnormal_fertilization1.18243309
53MP0002138_abnormal_hepatobiliary_system1.16774251
54MP0000569_abnormal_digit_pigmentation1.15895374
55MP0005646_abnormal_pituitary_gland1.15731247
56MP0000049_abnormal_middle_ear1.12716057
57MP0002876_abnormal_thyroid_physiology1.11033742
58MP0005332_abnormal_amino_acid1.09769306
59MP0004142_abnormal_muscle_tone1.09722165
60MP0003195_calcinosis1.09604453
61MP0005408_hypopigmentation1.08341986
62MP0003880_abnormal_central_pattern1.08262796
63MP0010386_abnormal_urinary_bladder1.07746286
64MP0002277_abnormal_respiratory_mucosa1.07252423
65MP0000490_abnormal_crypts_of1.05049891
66MP0002751_abnormal_autonomic_nervous1.04515023
67MP0008260_abnormal_autophagy1.02702159
68MP0002210_abnormal_sex_determination1.01631206
69MP0002234_abnormal_pharynx_morphology1.01250779
70MP0000613_abnormal_salivary_gland0.98842047
71MP0003656_abnormal_erythrocyte_physiolo0.97668550
72MP0004145_abnormal_muscle_electrophysio0.96775375
73MP0005084_abnormal_gallbladder_morpholo0.96681283
74MP0003567_abnormal_fetal_cardiomyocyte0.95719554
75MP0009046_muscle_twitch0.95501861
76MP0001929_abnormal_gametogenesis0.94548350
77MP0001727_abnormal_embryo_implantation0.91987727
78MP0009785_altered_susceptibility_to0.91913702
79MP0001145_abnormal_male_reproductive0.91197764
80MP0005075_abnormal_melanosome_morpholog0.91140450
81MP0005551_abnormal_eye_electrophysiolog0.90178759
82MP0000313_abnormal_cell_death0.90129441
83MP0001835_abnormal_antigen_presentation0.89193417
84MP0005499_abnormal_olfactory_system0.84781606
85MP0005394_taste/olfaction_phenotype0.84781606
86MP0006276_abnormal_autonomic_nervous0.84467453
87MP0009250_abnormal_appendicular_skeleto0.83268653
88MP0002653_abnormal_ependyma_morphology0.82508021
89MP0006054_spinal_hemorrhage0.82203555
90MP0001188_hyperpigmentation0.81517097
91MP0005379_endocrine/exocrine_gland_phen0.80980939
92MP0001119_abnormal_female_reproductive0.80173715
93MP0000653_abnormal_sex_gland0.79479254
94MP0002837_dystrophic_cardiac_calcinosis0.79093257
95MP0000647_abnormal_sebaceous_gland0.78799226
96MP0003941_abnormal_skin_development0.78774669
97MP0005389_reproductive_system_phenotype0.78564821
98MP0002160_abnormal_reproductive_system0.78342637
99MP0000762_abnormal_tongue_morphology0.78122283
100MP0002272_abnormal_nervous_system0.78005541
101MP0005409_darkened_coat_color0.77941159
102MP0000516_abnormal_urinary_system0.77052306
103MP0005367_renal/urinary_system_phenotyp0.77052306
104MP0002090_abnormal_vision0.76938406
105MP0005377_hearing/vestibular/ear_phenot0.76832765
106MP0003878_abnormal_ear_physiology0.76832765
107MP0004742_abnormal_vestibular_system0.76229919
108MP0009333_abnormal_splenocyte_physiolog0.75460992
109MP0004215_abnormal_myocardial_fiber0.74481552
110MP0001730_embryonic_growth_arrest0.74381674
111MP0000358_abnormal_cell_content/0.73796081
112MP0002282_abnormal_trachea_morphology0.71898344
113MP0001919_abnormal_reproductive_system0.71607810
114MP0003137_abnormal_impulse_conducting0.69366862
115MP0005636_abnormal_mineral_homeostasis0.69351180
116MP0005391_vision/eye_phenotype0.69256803
117MP0003937_abnormal_limbs/digits/tail_de0.68944291
118MP0001853_heart_inflammation0.68898685
119MP0009745_abnormal_behavioral_response0.68602384
120MP0002693_abnormal_pancreas_physiology0.68287244
121MP0002148_abnormal_hypersensitivity_rea0.67848525
122MP0002095_abnormal_skin_pigmentation0.67585301
123MP0003787_abnormal_imprinting0.67205627
124MP0003938_abnormal_ear_development0.67156525
125MP0001286_abnormal_eye_development0.66740917
126MP0009764_decreased_sensitivity_to0.66612091
127MP0005266_abnormal_metabolism0.66055588
128MP0003698_abnormal_male_reproductive0.66029951
129MP0001293_anophthalmia0.65680712
130MP0008877_abnormal_DNA_methylation0.65179419
131MP0008789_abnormal_olfactory_epithelium0.64066860
132MP0003724_increased_susceptibility_to0.63847863
133MP0001346_abnormal_lacrimal_gland0.63037683
134MP0008995_early_reproductive_senescence0.61519492
135MP0000350_abnormal_cell_proliferation0.60874639
136MP0005330_cardiomyopathy0.59466077
137MP0002019_abnormal_tumor_incidence0.57902454
138MP0005195_abnormal_posterior_eye0.57364057
139MP0000631_abnormal_neuroendocrine_gland0.56868593

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.23922029
2Abnormal mitochondria in muscle tissue (HP:0008316)5.65942173
3Mitochondrial inheritance (HP:0001427)5.41644068
4Acute encephalopathy (HP:0006846)5.21126773
5Progressive macrocephaly (HP:0004481)4.88222077
6Reticulocytopenia (HP:0001896)4.85759648
7Abnormality of cells of the erythroid lineage (HP:0012130)4.83502133
8Hepatocellular necrosis (HP:0001404)4.81043249
9Increased CSF lactate (HP:0002490)4.73445753
10Increased hepatocellular lipid droplets (HP:0006565)4.53848397
11Hepatic necrosis (HP:0002605)4.52937596
123-Methylglutaconic aciduria (HP:0003535)4.42002867
13Abnormal number of erythroid precursors (HP:0012131)4.41736458
14Decreased activity of mitochondrial respiratory chain (HP:0008972)4.28064065
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.28064065
16Lipid accumulation in hepatocytes (HP:0006561)4.20372157
17Renal Fanconi syndrome (HP:0001994)3.89292068
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.88788062
19Macrocytic anemia (HP:0001972)3.87815443
20Cerebral edema (HP:0002181)3.85047650
21Increased serum lactate (HP:0002151)3.65110506
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.63034482
23Abnormality of glycolysis (HP:0004366)3.55107405
24Increased serum pyruvate (HP:0003542)3.55107405
25Exercise intolerance (HP:0003546)3.47832748
26Respiratory failure (HP:0002878)3.45221431
27Increased intramyocellular lipid droplets (HP:0012240)3.41137345
28Optic disc pallor (HP:0000543)3.30364767
29Leukodystrophy (HP:0002415)3.28908578
30Lactic acidosis (HP:0003128)3.28643939
31Pallor (HP:0000980)3.23474105
32Aplasia/Hypoplasia of the sacrum (HP:0008517)3.11628417
33Exertional dyspnea (HP:0002875)3.10582605
34Pancreatic cysts (HP:0001737)2.97157996
35Increased muscle lipid content (HP:0009058)2.96412530
36Parakeratosis (HP:0001036)2.94501797
37Cerebral hypomyelination (HP:0006808)2.94081978
38Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.93306525
39Abnormality of midbrain morphology (HP:0002418)2.75702266
40Molar tooth sign on MRI (HP:0002419)2.75702266
41Pancreatic fibrosis (HP:0100732)2.73678459
42Type I transferrin isoform profile (HP:0003642)2.68058932
43True hermaphroditism (HP:0010459)2.62496452
44Abnormality of renal resorption (HP:0011038)2.60811182
45Microvesicular hepatic steatosis (HP:0001414)2.58422349
46Methylmalonic acidemia (HP:0002912)2.57347415
47Abnormal hemoglobin (HP:0011902)2.45131216
48Respiratory difficulties (HP:0002880)2.41297869
49Oral leukoplakia (HP:0002745)2.33672277
50CNS demyelination (HP:0007305)2.30562174
51Lethargy (HP:0001254)2.22758316
52Glycosuria (HP:0003076)2.18405243
53Abnormality of urine glucose concentration (HP:0011016)2.18405243
54Nephronophthisis (HP:0000090)2.18173210
55Abnormal rod and cone electroretinograms (HP:0008323)2.14920118
56Abolished electroretinogram (ERG) (HP:0000550)2.14611114
57Medial flaring of the eyebrow (HP:0010747)2.14107368
58Hyperglycinemia (HP:0002154)2.09024594
59Breast hypoplasia (HP:0003187)2.08548898
60Abnormality of aspartate family amino acid metabolism (HP:0010899)2.07328668
61Congenital ichthyosiform erythroderma (HP:0007431)2.05904053
62Reduced antithrombin III activity (HP:0001976)2.02204844
63Abnormal protein glycosylation (HP:0012346)2.01596674
64Abnormal glycosylation (HP:0012345)2.01596674
65Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.01596674
66Abnormal protein N-linked glycosylation (HP:0012347)2.01596674
67Rough bone trabeculation (HP:0100670)2.01181399
68Abnormality of placental membranes (HP:0011409)2.01126481
69Amniotic constriction ring (HP:0009775)2.01126481
70Absent rod-and cone-mediated responses on ERG (HP:0007688)2.01078701
71Congenital, generalized hypertrichosis (HP:0004540)2.00096303
72Duplicated collecting system (HP:0000081)1.99055805
73Sclerocornea (HP:0000647)1.98784372
74Poor head control (HP:0002421)1.98205720
75Triphalangeal thumb (HP:0001199)1.97178247
76Aplastic anemia (HP:0001915)1.96357366
77Hypothermia (HP:0002045)1.95394545
78Type 2 muscle fiber atrophy (HP:0003554)1.95066210
79Septo-optic dysplasia (HP:0100842)1.93940063
80Abnormality of serum amino acid levels (HP:0003112)1.92920658
81Emotional lability (HP:0000712)1.91878662
82Pendular nystagmus (HP:0012043)1.90417979
83Pancytopenia (HP:0001876)1.87464234
84Abnormality of the preputium (HP:0100587)1.85700182
85Absent thumb (HP:0009777)1.84222596
86Birth length less than 3rd percentile (HP:0003561)1.84014112
87Generalized aminoaciduria (HP:0002909)1.82353155
88Abnormality of dicarboxylic acid metabolism (HP:0010995)1.81738754
89Dicarboxylic aciduria (HP:0003215)1.81738754
90Hyperphosphaturia (HP:0003109)1.81334255
91Abnormality of alanine metabolism (HP:0010916)1.80774883
92Hyperalaninemia (HP:0003348)1.80774883
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.80774883
94Degeneration of anterior horn cells (HP:0002398)1.80625916
95Abnormality of the anterior horn cell (HP:0006802)1.80625916
96Decreased electroretinogram (ERG) amplitude (HP:0000654)1.78105234
97Methylmalonic aciduria (HP:0012120)1.75925308
98Blindness (HP:0000618)1.75694045
99Sparse eyelashes (HP:0000653)1.75026002
100Secondary amenorrhea (HP:0000869)1.74429629
101CNS hypomyelination (HP:0003429)1.74316433
102Abnormality of methionine metabolism (HP:0010901)1.74169981
103Aplasia/hypoplasia of the uterus (HP:0008684)1.73801785
104Microretrognathia (HP:0000308)1.73322793
105Absent radius (HP:0003974)1.72964595
106Bile duct proliferation (HP:0001408)1.72484813
107Abnormal biliary tract physiology (HP:0012439)1.72484813
108Abnormality of the labia minora (HP:0012880)1.72368431
109Abnormality of the renal cortex (HP:0011035)1.72312585
110Abnormality of the ileum (HP:0001549)1.70689064
111Type II lissencephaly (HP:0007260)1.70287746
112Abnormality of the renal medulla (HP:0100957)1.68871922
113Congenital stationary night blindness (HP:0007642)1.67364608
11411 pairs of ribs (HP:0000878)1.66431650
115Colon cancer (HP:0003003)1.66002404
116Neutropenia (HP:0001875)1.65371901
117X-linked dominant inheritance (HP:0001423)1.65287919
118Renal cortical cysts (HP:0000803)1.64651661
119Abnormality of the renal collecting system (HP:0004742)1.63139144
120Congenital primary aphakia (HP:0007707)1.62800093
121Nausea (HP:0002018)1.61771769
122Constricted visual fields (HP:0001133)1.60450716
123Carpal bone hypoplasia (HP:0001498)1.59517327
124IgG deficiency (HP:0004315)1.59278224
125Aplasia/Hypoplasia of the uvula (HP:0010293)1.58798916
126Severe visual impairment (HP:0001141)1.58083413
127Aplasia involving forearm bones (HP:0009822)1.57623198
128Absent forearm bone (HP:0003953)1.57623198
129Attenuation of retinal blood vessels (HP:0007843)1.57115277
130Abnormal trabecular bone morphology (HP:0100671)1.55850460
131Horseshoe kidney (HP:0000085)1.53558225
132Concave nail (HP:0001598)1.52948517
133Meckel diverticulum (HP:0002245)1.52477277
134Premature graying of hair (HP:0002216)1.51952997
135Abnormality of the heme biosynthetic pathway (HP:0010472)1.50788161
136Prolonged neonatal jaundice (HP:0006579)1.49894809

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.78949320
2BUB14.11007213
3STK164.02621621
4NME23.84563203
5EIF2AK13.63691058
6TLK13.59918781
7PBK3.58503055
8MAP4K23.14189424
9WEE12.87415658
10NUAK12.84991675
11TESK22.71790523
12SRPK12.43447309
13VRK12.33480957
14MAP3K122.31448308
15NME12.21913382
16BCKDK1.93749368
17EIF2AK31.92965986
18FRK1.71370444
19TRIM281.63583874
20TAF11.61456646
21PLK41.56361969
22MKNK11.54878206
23LIMK11.48180879
24DYRK31.46354853
25TXK1.46054804
26TESK11.45981737
27PIM21.45742594
28KDR1.45216040
29INSRR1.41814459
30CDK191.38307932
31DYRK21.30052209
32STK391.26667897
33TNIK1.25477261
34CDC71.22452404
35TTK1.19025287
36EIF2AK21.18222909
37AURKA1.16112350
38PINK11.14405646
39AURKB1.12596319
40PLK11.10651999
41MST41.08643048
42MAPKAPK51.07249197
43BRAF1.05112318
44ZAK1.03799221
45OBSCN1.02236352
46BCR1.01688091
47BRSK20.98719778
48MUSK0.96001295
49RPS6KA50.93757606
50GRK70.92129237
51IRAK20.91961559
52MKNK20.91727187
53PASK0.89534174
54CSNK1G20.88306125
55ACVR1B0.87935546
56IRAK40.86631462
57PLK20.86224917
58CCNB10.84319264
59ADRBK20.83355475
60TAOK30.83007754
61MYLK0.82296279
62CASK0.82115010
63IKBKB0.81181823
64TIE10.80373686
65MAP3K40.80362263
66CSNK2A10.77792707
67TSSK60.77434871
68CDK70.75982806
69NEK20.74217331
70ILK0.74008862
71ABL20.73962079
72DAPK10.73663287
73WNK40.71206185
74ATR0.71031625
75WNK30.70917776
76STK40.69499557
77IRAK10.69314230
78CSNK2A20.68821278
79ARAF0.68662200
80CSNK1G30.68648064
81IRAK30.68612737
82RPS6KB20.68201574
83OXSR10.67945593
84BMPR1B0.66949083
85MAP2K70.66536205
86CDK80.65983776
87NEK10.65934345
88PLK30.65115844
89MAP2K20.62007513
90PAK10.60970906
91PRKCI0.59499217
92MAPK130.59344968
93CSNK1A1L0.59208382
94RPS6KA40.58849112
95PIK3CG0.56799803
96CHEK20.55886911
97BLK0.55293212
98UHMK10.53434115
99PRKCE0.51678997
100ERBB30.50211752
101BRSK10.49500583
102PRKCQ0.49158691
103MAPKAPK30.49104185
104MAP3K110.48759657
105KIT0.47956679
106DAPK30.47213119
107MAP3K80.45408178
108LRRK20.45351881
109NLK0.44809244
110YES10.44186032
111MET0.44000914
112PRKCG0.43478271
113TGFBR10.43419277
114TEC0.43110345
115PNCK0.42175779
116GRK10.39954980
117NEK90.39742364
118ITK0.39626662
119PDK30.38705393
120PDK40.38705393
121CSNK1A10.38466665
122MAPK150.37536048
123GRK50.35246472
124CSNK1G10.34275076
125ADRBK10.33823265
126PAK30.33129710
127CHEK10.33047367
128CDK30.32226635
129CLK10.31034718
130CAMK2D0.27275539
131EPHB20.26992535
132PDK20.26731814
133PKN10.26596929

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.18464105
2Proteasome_Homo sapiens_hsa030504.19686891
3Oxidative phosphorylation_Homo sapiens_hsa001903.75995661
4Parkinsons disease_Homo sapiens_hsa050123.42386911
5RNA polymerase_Homo sapiens_hsa030203.30955195
6DNA replication_Homo sapiens_hsa030303.15469785
7Mismatch repair_Homo sapiens_hsa034302.91770574
8Protein export_Homo sapiens_hsa030602.90696711
9Huntingtons disease_Homo sapiens_hsa050162.53322487
10Homologous recombination_Homo sapiens_hsa034402.40884708
11Spliceosome_Homo sapiens_hsa030402.33440747
12Pyrimidine metabolism_Homo sapiens_hsa002402.31306094
13Alzheimers disease_Homo sapiens_hsa050102.29061294
14Nucleotide excision repair_Homo sapiens_hsa034202.13920751
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.08613226
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.96909768
17Base excision repair_Homo sapiens_hsa034101.82355985
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.79121141
19Fanconi anemia pathway_Homo sapiens_hsa034601.56560749
20RNA transport_Homo sapiens_hsa030131.55828959
21Fatty acid elongation_Homo sapiens_hsa000621.54867164
22Basal transcription factors_Homo sapiens_hsa030221.53712979
23Folate biosynthesis_Homo sapiens_hsa007901.51214035
24One carbon pool by folate_Homo sapiens_hsa006701.49880426
25Non-homologous end-joining_Homo sapiens_hsa034501.46877410
26Purine metabolism_Homo sapiens_hsa002301.34463213
27RNA degradation_Homo sapiens_hsa030181.32460792
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.31525783
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31286047
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.30318588
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.29423811
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.25653195
33Cardiac muscle contraction_Homo sapiens_hsa042601.18384203
34Primary immunodeficiency_Homo sapiens_hsa053401.15865434
35Butanoate metabolism_Homo sapiens_hsa006501.13540000
36Type I diabetes mellitus_Homo sapiens_hsa049401.10700462
37Allograft rejection_Homo sapiens_hsa053301.08591285
38Glutathione metabolism_Homo sapiens_hsa004801.07601998
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.07122149
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.06917555
41Graft-versus-host disease_Homo sapiens_hsa053321.06905602
42Cell cycle_Homo sapiens_hsa041101.04473585
43Sulfur metabolism_Homo sapiens_hsa009201.03464139
44Steroid biosynthesis_Homo sapiens_hsa001000.99521352
45Collecting duct acid secretion_Homo sapiens_hsa049660.98940195
46Arachidonic acid metabolism_Homo sapiens_hsa005900.97328543
47Sulfur relay system_Homo sapiens_hsa041220.95633919
48Linoleic acid metabolism_Homo sapiens_hsa005910.94752295
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87294527
50Systemic lupus erythematosus_Homo sapiens_hsa053220.87104502
51Metabolic pathways_Homo sapiens_hsa011000.85706442
52Phototransduction_Homo sapiens_hsa047440.85095849
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.83374517
54Caffeine metabolism_Homo sapiens_hsa002320.81943921
55Rheumatoid arthritis_Homo sapiens_hsa053230.81732089
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77994916
57Nitrogen metabolism_Homo sapiens_hsa009100.75419789
58Propanoate metabolism_Homo sapiens_hsa006400.73920469
59Pyruvate metabolism_Homo sapiens_hsa006200.73558047
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.73047537
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.72533557
62Arginine and proline metabolism_Homo sapiens_hsa003300.72090610
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71531458
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71445031
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.65473628
66Antigen processing and presentation_Homo sapiens_hsa046120.65236916
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61683467
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61447963
69Ether lipid metabolism_Homo sapiens_hsa005650.60655451
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60287291
71Carbon metabolism_Homo sapiens_hsa012000.59964034
72Peroxisome_Homo sapiens_hsa041460.59575988
73Histidine metabolism_Homo sapiens_hsa003400.59507121
74Pentose phosphate pathway_Homo sapiens_hsa000300.59293526
75Drug metabolism - other enzymes_Homo sapiens_hsa009830.58499726
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58235411
77Epstein-Barr virus infection_Homo sapiens_hsa051690.55002765
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52658057
79Primary bile acid biosynthesis_Homo sapiens_hsa001200.52257427
80Retinol metabolism_Homo sapiens_hsa008300.51266021
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51232205
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49303016
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48459934
84p53 signaling pathway_Homo sapiens_hsa041150.47913461
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46812496
86Tyrosine metabolism_Homo sapiens_hsa003500.46599409
87Biosynthesis of amino acids_Homo sapiens_hsa012300.46443601
88Sphingolipid metabolism_Homo sapiens_hsa006000.44041186
89Maturity onset diabetes of the young_Homo sapiens_hsa049500.43664943
90Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.43395632
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41938355
92Selenocompound metabolism_Homo sapiens_hsa004500.41424893
93Steroid hormone biosynthesis_Homo sapiens_hsa001400.40598013
94Vitamin B6 metabolism_Homo sapiens_hsa007500.40123559
95Chemical carcinogenesis_Homo sapiens_hsa052040.39732211
96mRNA surveillance pathway_Homo sapiens_hsa030150.37731339
97Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37651104
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36714139
99Phenylalanine metabolism_Homo sapiens_hsa003600.36048366
100Cyanoamino acid metabolism_Homo sapiens_hsa004600.34598078
101Mineral absorption_Homo sapiens_hsa049780.32252506
102Other glycan degradation_Homo sapiens_hsa005110.29817763
103Hematopoietic cell lineage_Homo sapiens_hsa046400.27240951
104Fatty acid degradation_Homo sapiens_hsa000710.26793719
105beta-Alanine metabolism_Homo sapiens_hsa004100.25225818
1062-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.24488661
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.22531760
108N-Glycan biosynthesis_Homo sapiens_hsa005100.21499143
109Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20443428
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.20117446
111Vibrio cholerae infection_Homo sapiens_hsa051100.19966605
112Fructose and mannose metabolism_Homo sapiens_hsa000510.18967421
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18815311
114Alcoholism_Homo sapiens_hsa050340.18172788
115Galactose metabolism_Homo sapiens_hsa000520.18010148
116Asthma_Homo sapiens_hsa053100.17745191
117Fat digestion and absorption_Homo sapiens_hsa049750.16272306
118Regulation of autophagy_Homo sapiens_hsa041400.15555532
119Herpes simplex infection_Homo sapiens_hsa051680.15110616
120Tryptophan metabolism_Homo sapiens_hsa003800.11951137
121Autoimmune thyroid disease_Homo sapiens_hsa053200.11722333
122Vitamin digestion and absorption_Homo sapiens_hsa049770.11360678

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