CNOT6L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tolerance induction (GO:0002507)5.52447269
2activated T cell proliferation (GO:0050798)5.40653373
3positive regulation of gamma-delta T cell activation (GO:0046645)5.18941565
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.10372493
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.10372493
6antigen processing and presentation of endogenous antigen (GO:0019883)4.43877252
7type B pancreatic cell development (GO:0003323)4.30835825
8cytoplasmic mRNA processing body assembly (GO:0033962)4.26957970
9mitotic sister chromatid cohesion (GO:0007064)4.19822818
10regulation of gamma-delta T cell differentiation (GO:0045586)4.14544972
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.97312788
12negative regulation of cell killing (GO:0031342)3.97312788
13regulation of gamma-delta T cell activation (GO:0046643)3.87430079
14antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.86123169
15positive thymic T cell selection (GO:0045059)3.75990061
16alpha-beta T cell differentiation (GO:0046632)3.59866462
17definitive hemopoiesis (GO:0060216)3.58228744
18positive T cell selection (GO:0043368)3.50235838
19negative T cell selection (GO:0043383)3.49308422
20positive regulation of granulocyte differentiation (GO:0030854)3.48975591
21protein K11-linked deubiquitination (GO:0035871)3.48113968
22positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.47102742
23hepatocyte apoptotic process (GO:0097284)3.46105483
24glandular epithelial cell development (GO:0002068)3.43960266
25regulation of alpha-beta T cell proliferation (GO:0046640)3.42449069
26positive regulation of alpha-beta T cell proliferation (GO:0046641)3.41261711
27regulation of germinal center formation (GO:0002634)3.39932978
28regulation of regulatory T cell differentiation (GO:0045589)3.39621904
29COPI coating of Golgi vesicle (GO:0048205)3.39020380
30Golgi transport vesicle coating (GO:0048200)3.39020380
31alpha-beta T cell activation (GO:0046631)3.34364982
32negative regulation of cAMP-mediated signaling (GO:0043951)3.31243081
33regulation of B cell receptor signaling pathway (GO:0050855)3.30794604
34negative regulation of T cell mediated immunity (GO:0002710)3.28490290
35regulation of isotype switching to IgG isotypes (GO:0048302)3.27538210
36negative thymic T cell selection (GO:0045060)3.26175330
37corticosteroid receptor signaling pathway (GO:0031958)3.23987972
38response to interleukin-15 (GO:0070672)3.23964572
39positive regulation of histone deacetylation (GO:0031065)3.23413371
40negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.19032303
41negative regulation of T-helper cell differentiation (GO:0045623)3.19032303
42monoubiquitinated protein deubiquitination (GO:0035520)3.17430167
43thymic T cell selection (GO:0045061)3.15506868
44mitotic chromosome condensation (GO:0007076)3.14009323
45regulation of histone H3-K27 methylation (GO:0061085)3.11808815
46phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.09207213
47gland morphogenesis (GO:0022612)3.08691994
48T cell selection (GO:0045058)3.08599673
49regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.02770655
50positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.02770655
51positive regulation of B cell differentiation (GO:0045579)3.02759639
52T cell differentiation involved in immune response (GO:0002292)2.99754713
53alpha-beta T cell differentiation involved in immune response (GO:0002293)2.99754713
54alpha-beta T cell activation involved in immune response (GO:0002287)2.99754713
55positive regulation of T cell differentiation in thymus (GO:0033089)2.97610007
56regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.95179532
57regulation of natural killer cell mediated immunity (GO:0002715)2.95179532
58regulation of interleukin-12 biosynthetic process (GO:0045075)2.91580634
59negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.90881682
60B cell receptor signaling pathway (GO:0050853)2.90689211
61JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.88934224
62megakaryocyte development (GO:0035855)2.87953877
63myoblast migration (GO:0051451)2.86039237
64COPII vesicle coating (GO:0048208)2.85104796
65positive regulation of natural killer cell mediated immunity (GO:0002717)2.85054693
66leukocyte aggregation (GO:0070486)2.84837256
67cellular response to interleukin-15 (GO:0071350)2.84670085
68histone H2A monoubiquitination (GO:0035518)2.80721448
69interkinetic nuclear migration (GO:0022027)2.79356380
70regulation of establishment of cell polarity (GO:2000114)2.77833086
71glucocorticoid receptor signaling pathway (GO:0042921)2.76904694
72sister chromatid cohesion (GO:0007062)2.74278726
73negative regulation of lymphocyte mediated immunity (GO:0002707)2.73643677
74interferon-gamma production (GO:0032609)2.73624566
75growth hormone receptor signaling pathway (GO:0060396)2.72845824
76mast cell activation involved in immune response (GO:0002279)2.72625763
77mast cell degranulation (GO:0043303)2.72625763
78negative regulation of protein oligomerization (GO:0032460)2.71459950
79regulation of B cell differentiation (GO:0045577)2.71287224
80positive regulation of tolerance induction (GO:0002645)2.69374301
81protein K48-linked deubiquitination (GO:0071108)2.67318729
82endocrine pancreas development (GO:0031018)2.66113502
83regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.65295785
84positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.65295785
85regulation of leukocyte mediated cytotoxicity (GO:0001910)2.65258818
86neural tube formation (GO:0001841)2.64361421
87positive regulation of protein deacetylation (GO:0090312)2.64302966
88negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.63672816
89positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.63278884
90positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.63235755
91CD4-positive, alpha-beta T cell activation (GO:0035710)2.61808948
92T cell costimulation (GO:0031295)2.61360460
93antigen processing and presentation via MHC class Ib (GO:0002475)2.60204227
94positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.60145009
95regulation of T cell mediated cytotoxicity (GO:0001914)2.58271612
96lymphocyte costimulation (GO:0031294)2.58096226
97T cell migration (GO:0072678)2.58046328
98regulation of T cell tolerance induction (GO:0002664)2.57758936
99negative regulation of bone resorption (GO:0045779)2.57662467
100histone mRNA catabolic process (GO:0071044)2.57479692
101T cell proliferation (GO:0042098)2.56785074
102T cell differentiation (GO:0030217)2.56574661
103mucosal-associated lymphoid tissue development (GO:0048537)2.54721265
104Peyers patch development (GO:0048541)2.54721265
105cellular extravasation (GO:0045123)2.54668642
106negative regulation of adaptive immune response (GO:0002820)2.53339148
107negative regulation of erythrocyte differentiation (GO:0045647)2.52685030
108T cell activation (GO:0042110)2.52610051
109regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.52526530
110histone H3-K36 demethylation (GO:0070544)2.51004414
111positive regulation of mRNA catabolic process (GO:0061014)2.50671369
112regulation of establishment or maintenance of cell polarity (GO:0032878)2.49111789
113radial glial cell differentiation (GO:0060019)2.48776155
114positive regulation of DNA recombination (GO:0045911)2.48281040
115regulation of cell killing (GO:0031341)2.47964850
116regulation of mRNA catabolic process (GO:0061013)2.47810920
117dentate gyrus development (GO:0021542)2.47189560
118positive regulation of isotype switching (GO:0045830)2.46979395
119regulation of tolerance induction (GO:0002643)2.46949989
120negative regulation of B cell proliferation (GO:0030889)2.46837248
121positive regulation of calcium-mediated signaling (GO:0050850)2.46174906
122histone H3-K4 methylation (GO:0051568)2.46044846
123regulation of alpha-beta T cell activation (GO:0046634)2.45882121
124protein K63-linked deubiquitination (GO:0070536)2.45709939
125necroptotic process (GO:0070266)2.43887929
126leukocyte tethering or rolling (GO:0050901)2.42566468
127CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.40924520
128T-helper cell differentiation (GO:0042093)2.40924520
129regulation of granulocyte differentiation (GO:0030852)2.40673244
130negative regulation of phagocytosis (GO:0050765)2.40499514
131T cell homeostasis (GO:0043029)2.38994799
132columnar/cuboidal epithelial cell development (GO:0002066)2.37200829
133NIK/NF-kappaB signaling (GO:0038061)2.35778804
134embryonic hemopoiesis (GO:0035162)2.33479489
135positive regulation of keratinocyte differentiation (GO:0045618)2.32567557
136peptidyl-lysine trimethylation (GO:0018023)2.32434878
137antigen receptor-mediated signaling pathway (GO:0050851)2.31979689
138meiotic chromosome segregation (GO:0045132)2.30518051
139positive regulation of macrophage differentiation (GO:0045651)2.30277858
140regulation of RIG-I signaling pathway (GO:0039535)2.29731890
141mast cell activation (GO:0045576)2.28884008
142positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.28848437
143positive regulation of histone H3-K4 methylation (GO:0051571)2.28101684
144histone H3-K4 trimethylation (GO:0080182)2.27663955
145regulation of necroptotic process (GO:0060544)2.27085701
146cellular response to growth hormone stimulus (GO:0071378)2.27042281
147regulation of T cell receptor signaling pathway (GO:0050856)2.25254941
148T cell receptor signaling pathway (GO:0050852)2.23452717
149CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.22959472
150V(D)J recombination (GO:0033151)2.22663906
151regulation of steroid hormone biosynthetic process (GO:0090030)2.22249271
152JAK-STAT cascade (GO:0007259)2.21822911
153positive regulation of defense response to virus by host (GO:0002230)2.21345448
154histone H3-K9 demethylation (GO:0033169)2.21277667

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.91084922
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.87383951
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.89198309
4E2F7_22180533_ChIP-Seq_HELA_Human3.50114627
5GATA1_22025678_ChIP-Seq_K562_Human3.29187113
6* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.03019064
7SCL_19346495_ChIP-Seq_HPC-7_Human2.97649659
8* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.96693388
9MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.83529782
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.82445796
11RUNX_20019798_ChIP-Seq_JUKART_Human2.78027008
12EGR1_19374776_ChIP-ChIP_THP-1_Human2.76048951
13IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.69047775
14MYC_22102868_ChIP-Seq_BL_Human2.67009027
15NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.54100081
16MYB_26560356_Chip-Seq_TH2_Human2.53610466
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.50032216
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.47220406
19EZH2_22144423_ChIP-Seq_EOC_Human2.38785271
20* MYB_26560356_Chip-Seq_TH1_Human2.21139261
21SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.21000669
22SMAD_19615063_ChIP-ChIP_OVARY_Human2.18700395
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.18508832
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.15364017
25* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.14308407
26TCF7_22412390_ChIP-Seq_EML_Mouse2.10878512
27MYB_21317192_ChIP-Seq_ERMYB_Mouse2.02663931
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85690537
29BP1_19119308_ChIP-ChIP_Hs578T_Human1.84962027
30* GATA3_27048872_Chip-Seq_THYMUS_Human1.84304386
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.83721519
32IRF8_27001747_Chip-Seq_BMDM_Mouse1.83266755
33GBX2_23144817_ChIP-Seq_PC3_Human1.81058256
34VDR_22108803_ChIP-Seq_LS180_Human1.74009849
35* UTX_26944678_Chip-Seq_JUKART_Human1.71453469
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67180880
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67013770
38* MAF_26560356_Chip-Seq_TH1_Human1.66232699
39* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.66083323
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.56555677
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.55853793
42TAF15_26573619_Chip-Seq_HEK293_Human1.54437443
43* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.53837686
44SPI1_23547873_ChIP-Seq_NB4_Human1.53437081
45IGF1R_20145208_ChIP-Seq_DFB_Human1.48194598
46PRDM14_20953172_ChIP-Seq_ESCs_Human1.47792107
47* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47636550
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.46352168
49STAT4_19710469_ChIP-ChIP_TH1__Mouse1.46038001
50* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.45741557
51ER_23166858_ChIP-Seq_MCF-7_Human1.45739794
52IRF8_21731497_ChIP-ChIP_J774_Mouse1.42338235
53* RUNX1_22412390_ChIP-Seq_EML_Mouse1.42038918
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40522201
55PU_27001747_Chip-Seq_BMDM_Mouse1.39867624
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37497683
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37181028
58ZNF274_21170338_ChIP-Seq_K562_Hela1.37061211
59RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36978819
60VDR_21846776_ChIP-Seq_THP-1_Human1.36007668
61PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.35974255
62FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.35802802
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.35536853
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.34039208
65SPI1_23127762_ChIP-Seq_K562_Human1.33839125
66VDR_24763502_ChIP-Seq_THP-1_Human1.33561186
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.32330262
68RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.30348453
69* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.29015383
70TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.28860923
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.28850827
72Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26529991
73EZH2_27294783_Chip-Seq_NPCs_Mouse1.26394257
74* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.24684091
75CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24070311
76DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.23866910
77TCF4_23295773_ChIP-Seq_U87_Human1.23719488
78MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.23568215
79STAT3_23295773_ChIP-Seq_U87_Human1.23350677
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22126900
81GATA3_26560356_Chip-Seq_TH2_Human1.21776082
82PKCTHETA_26484144_Chip-Seq_BREAST_Human1.21067075
83FLI1_21867929_ChIP-Seq_TH2_Mouse1.20526960
84P300_19829295_ChIP-Seq_ESCs_Human1.20011525
85RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.19751934
86UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19529679
87EWS_26573619_Chip-Seq_HEK293_Human1.19524862
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19448869
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18971161
90* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.18619636
91BCAT_22108803_ChIP-Seq_LS180_Human1.18503897
92* GATA2_21666600_ChIP-Seq_HMVEC_Human1.17609613
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.16636190
94E2F1_21310950_ChIP-Seq_MCF-7_Human1.15211540
95SMAD4_21799915_ChIP-Seq_A2780_Human1.13453725
96FOXO3_23340844_ChIP-Seq_DLD1_Human1.11822783
97NANOG_18555785_Chip-Seq_ESCs_Mouse1.08443331
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08186841
99CBP_20019798_ChIP-Seq_JUKART_Human1.08148878
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08148878
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07229855
102STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.06992419
103* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06854496
104CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05380909
105TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05227533
106OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04864055
107* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.04161933
108* AR_25329375_ChIP-Seq_VCAP_Human1.03926317
109PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03872047
110ETS1_22383799_ChIP-Seq_G1ME_Mouse1.03461447
111SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03239191
112IRF1_19129219_ChIP-ChIP_H3396_Human1.03152453
113PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03051434
114* FUS_26573619_Chip-Seq_HEK293_Human1.02441159
115KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02247014
116OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02012068
117GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01617343
118ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01138653
119CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00982868
120FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99496390
121ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98553619
122BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97839280
123TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97572001
124CRX_20693478_ChIP-Seq_RETINA_Mouse0.97340522
125P53_22387025_ChIP-Seq_ESCs_Mouse0.97111452
126EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96580235
127RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95662569
128CTBP1_25329375_ChIP-Seq_LNCAP_Human0.95516228
129SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.95501953
130KDM2B_26808549_Chip-Seq_REH_Human0.95403870
131TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.95387836
132PIAS1_25552417_ChIP-Seq_VCAP_Human0.95128154
133CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.94798221
134KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.94617291
135PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94245117
136TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.93983257
137* FOXA1_25552417_ChIP-Seq_VCAP_Human0.93684073
138* POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.93568879
139* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93568879
140E2F4_17652178_ChIP-ChIP_JURKAT_Human0.93485939
141E2F1_18555785_Chip-Seq_ESCs_Mouse0.92980498
142FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.92967985
143FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92110663
144AR_21572438_ChIP-Seq_LNCaP_Human0.91740928
145ARNT_22903824_ChIP-Seq_MCF-7_Human0.91393623
146CIITA_25753668_ChIP-Seq_RAJI_Human0.91349098
147CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.91259230
148* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90651359
149GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.90177094
150KDM2B_26808549_Chip-Seq_DND41_Human0.89868840
151* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89806779
152TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86414026
153DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86146935
154KDM2B_26808549_Chip-Seq_JURKAT_Human0.85976529
155GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85772767
156FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85472490
157VDR_24787735_ChIP-Seq_THP-1_Human0.85034245
158GATA3_26560356_Chip-Seq_TH1_Human0.84025599
159GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.83688854
160ELF1_17652178_ChIP-ChIP_JURKAT_Human0.83428260
161NFIB_24661679_ChIP-Seq_LUNG_Mouse0.82825653
162LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.82559208
163VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.82090350
164SMRT_27268052_Chip-Seq_Bcells_Human0.81766736
165GATA2_19941826_ChIP-Seq_K562_Human0.81520697
166GATA1_19941826_ChIP-Seq_K562_Human0.81427398

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002877_abnormal_melanocyte_morpholog3.40000600
2MP0003763_abnormal_thymus_physiology3.17618438
3MP0003300_gastrointestinal_ulcer3.05912627
4MP0006054_spinal_hemorrhage2.97950742
5MP0010234_abnormal_vibrissa_follicle2.65398631
6MP0002166_altered_tumor_susceptibility2.57216132
7MP0005671_abnormal_response_to2.56290817
8MP0002009_preneoplasia2.43111623
9MP0002396_abnormal_hematopoietic_system2.40188555
10MP0001835_abnormal_antigen_presentation2.32139721
11MP0004381_abnormal_hair_follicle2.24506983
12MP0001800_abnormal_humoral_immune2.16414395
13MP0000685_abnormal_immune_system2.13993238
14MP0002006_tumorigenesis2.06543456
15MP0004808_abnormal_hematopoietic_stem2.01548458
16MP0005387_immune_system_phenotype1.96713679
17MP0001790_abnormal_immune_system1.96713679
18MP0002398_abnormal_bone_marrow1.93841647
19MP0002693_abnormal_pancreas_physiology1.92841312
20MP0003183_abnormal_peptide_metabolism1.89968825
21MP0001944_abnormal_pancreas_morphology1.79582954
22MP0002723_abnormal_immune_serum1.76755473
23MP0002420_abnormal_adaptive_immunity1.76547224
24MP0002452_abnormal_antigen_presenting1.74077328
25MP0002138_abnormal_hepatobiliary_system1.73752508
26MP0001819_abnormal_immune_cell1.73555956
27MP0005000_abnormal_immune_tolerance1.71458843
28MP0004264_abnormal_extraembryonic_tissu1.69512961
29MP0003787_abnormal_imprinting1.68789270
30MP0005310_abnormal_salivary_gland1.67770282
31MP0002928_abnormal_bile_duct1.62612853
32MP0004130_abnormal_muscle_cell1.61825142
33MP0005220_abnormal_exocrine_pancreas1.61575472
34MP0000703_abnormal_thymus_morphology1.61111970
35MP0010155_abnormal_intestine_physiology1.59431883
36MP0000716_abnormal_immune_system1.58811408
37MP0001873_stomach_inflammation1.58702700
38MP0003646_muscle_fatigue1.58407999
39MP0001851_eye_inflammation1.53322068
40MP0006082_CNS_inflammation1.49924895
41MP0000569_abnormal_digit_pigmentation1.48633801
42MP0004947_skin_inflammation1.48158981
43MP0000465_gastrointestinal_hemorrhage1.46062751
44MP0003303_peritoneal_inflammation1.45602630
45MP0005389_reproductive_system_phenotype1.45102592
46MP0002405_respiratory_system_inflammati1.44359044
47MP0000689_abnormal_spleen_morphology1.42918892
48MP0005464_abnormal_platelet_physiology1.41401893
49MP0002722_abnormal_immune_system1.41041744
50MP0003436_decreased_susceptibility_to1.40998172
51MP0005379_endocrine/exocrine_gland_phen1.39645147
52MP0001545_abnormal_hematopoietic_system1.39324524
53MP0005397_hematopoietic_system_phenotyp1.39324524
54MP0008877_abnormal_DNA_methylation1.38158256
55MP0005025_abnormal_response_to1.37686953
56MP0005408_hypopigmentation1.32043889
57MP0008995_early_reproductive_senescence1.31973857
58MP0003866_abnormal_defecation1.31232398
59MP0002429_abnormal_blood_cell1.30768303
60MP0008057_abnormal_DNA_replication1.29715984
61MP0002277_abnormal_respiratory_mucosa1.29636505
62MP0001986_abnormal_taste_sensitivity1.26935346
63MP0003943_abnormal_hepatobiliary_system1.26916653
64MP0003724_increased_susceptibility_to1.26563619
65MP0001845_abnormal_inflammatory_respons1.21911623
66MP0002419_abnormal_innate_immunity1.20671376
67MP0009785_altered_susceptibility_to1.18898983
68MP0009333_abnormal_splenocyte_physiolog1.18405279
69MP0003252_abnormal_bile_duct1.16280690
70MP0010368_abnormal_lymphatic_system1.15564471
71MP0002876_abnormal_thyroid_physiology1.14360902
72MP0008961_abnormal_basal_metabolism1.13132314
73MP0000013_abnormal_adipose_tissue1.12021276
74MP0002837_dystrophic_cardiac_calcinosis1.11993534
75MP0000015_abnormal_ear_pigmentation1.11245330
76MP0000490_abnormal_crypts_of1.10032239
77MP0005646_abnormal_pituitary_gland1.08711359
78MP0003868_abnormal_feces_composition1.08116148
79MP0010094_abnormal_chromosome_stability1.07233466
80MP0001501_abnormal_sleep_pattern1.05960843
81MP0005076_abnormal_cell_differentiation1.04873642
82MP0004185_abnormal_adipocyte_glucose1.03052328
83MP0000003_abnormal_adipose_tissue1.02329932
84MP0002160_abnormal_reproductive_system1.01200472
85MP0008007_abnormal_cellular_replicative1.00250533
86MP0010352_gastrointestinal_tract_polyps1.00031655
87MP0003693_abnormal_embryo_hatching0.99362170
88MP0003195_calcinosis0.98540477
89MP0002019_abnormal_tumor_incidence0.98421791
90MP0005451_abnormal_body_composition0.97146530
91MP0000427_abnormal_hair_cycle0.93457704
92MP0003045_fibrosis0.92077352
93MP0002148_abnormal_hypersensitivity_rea0.91732189
94MP0001915_intracranial_hemorrhage0.91592245
95MP0005174_abnormal_tail_pigmentation0.91286633
96MP0009278_abnormal_bone_marrow0.88486066
97MP0010307_abnormal_tumor_latency0.87267345
98MP0005645_abnormal_hypothalamus_physiol0.86115735
99MP0004142_abnormal_muscle_tone0.85846784
100MP0002638_abnormal_pupillary_reflex0.84811246
101MP0004885_abnormal_endolymph0.84728976
102MP0000613_abnormal_salivary_gland0.84698260
103MP0003077_abnormal_cell_cycle0.82911591
104MP0002163_abnormal_gland_morphology0.80974255
105MP0001853_heart_inflammation0.79936281
106MP0001533_abnormal_skeleton_physiology0.78850130
107MP0001919_abnormal_reproductive_system0.77368355
108MP0004742_abnormal_vestibular_system0.76612193
109MP0005365_abnormal_bile_salt0.76269473
110MP0008469_abnormal_protein_level0.75445051
111MP0000858_altered_metastatic_potential0.75340829
112MP0009745_abnormal_behavioral_response0.74915697
113MP0006292_abnormal_olfactory_placode0.74822362
114MP0001968_abnormal_touch/_nociception0.73502261
115MP0005075_abnormal_melanosome_morpholog0.73462423
116MP0002078_abnormal_glucose_homeostasis0.73393399
117MP0010678_abnormal_skin_adnexa0.72702794
118MP0002060_abnormal_skin_morphology0.72653318
119MP0002933_joint_inflammation0.72614124
120MP0009764_decreased_sensitivity_to0.71843593
121MP0000631_abnormal_neuroendocrine_gland0.71116123
122MP0001502_abnormal_circadian_rhythm0.70339026
123MP0001216_abnormal_epidermal_layer0.70250950
124MP0003795_abnormal_bone_structure0.70061119
125MP0002095_abnormal_skin_pigmentation0.69344005
126MP0001119_abnormal_female_reproductive0.68755457
127MP0001765_abnormal_ion_homeostasis0.68521619
128MP0004510_myositis0.68430171
129MP0001879_abnormal_lymphatic_vessel0.68396154
130MP0004484_altered_response_of0.66765333
131MP0005551_abnormal_eye_electrophysiolog0.66367554
132MP0002102_abnormal_ear_morphology0.65597235
133MP0001663_abnormal_digestive_system0.64743149
134MP0005647_abnormal_sex_gland0.64426335
135MP0008872_abnormal_physiological_respon0.63365732
136MP0003879_abnormal_hair_cell0.62758600
137MP0005448_abnormal_energy_balance0.60827445
138MP0010386_abnormal_urinary_bladder0.60081378
139MP0004043_abnormal_pH_regulation0.59982536

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.73523082
2Stomatitis (HP:0010280)4.39870109
3Elevated erythrocyte sedimentation rate (HP:0003565)4.12721682
4T lymphocytopenia (HP:0005403)3.67823152
5Spondylolisthesis (HP:0003302)3.65492573
6Fair hair (HP:0002286)3.49242515
7Abnormality of T cell number (HP:0011839)3.42464743
8Volvulus (HP:0002580)3.39872824
9Recurrent viral infections (HP:0004429)3.32308708
10Abnormal delayed hypersensitivity skin test (HP:0002963)3.29090623
11Abnormality of endocrine pancreas physiology (HP:0012093)3.12704415
12Abnormality of the pancreatic islet cells (HP:0006476)3.12704415
13Acute myeloid leukemia (HP:0004808)3.06245767
14Thyroiditis (HP:0100646)3.05911859
15IgM deficiency (HP:0002850)3.05071346
16Myositis (HP:0100614)3.03033644
17Thrombocytosis (HP:0001894)2.98816943
18Stomach cancer (HP:0012126)2.96811798
19Abnormality of T cells (HP:0002843)2.94734487
20Generalized hypopigmentation of hair (HP:0011358)2.94662670
21Lip pit (HP:0100267)2.92760479
22Pustule (HP:0200039)2.90176400
23Recurrent bacterial skin infections (HP:0005406)2.87962040
24Papilledema (HP:0001085)2.86370510
25Oligodactyly (hands) (HP:0001180)2.85120929
26Genetic anticipation (HP:0003743)2.83826014
27Eosinophilia (HP:0001880)2.82921899
28Hypoglycemic seizures (HP:0002173)2.82396399
29Recurrent fungal infections (HP:0002841)2.80449525
30Pancreatic islet-cell hyperplasia (HP:0004510)2.80234252
31Hyperglycemia (HP:0003074)2.76099035
32Abnormality of the prostate (HP:0008775)2.73670450
33Progressive cerebellar ataxia (HP:0002073)2.73333779
34Insulin-resistant diabetes mellitus (HP:0000831)2.61237911
35Hyperinsulinemic hypoglycemia (HP:0000825)2.61121260
36Abnormality of T cell physiology (HP:0011840)2.60759311
37Recurrent bronchitis (HP:0002837)2.58967521
38Recurrent abscess formation (HP:0002722)2.58022942
39Mediastinal lymphadenopathy (HP:0100721)2.56356871
40Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.53403223
41Panhypogammaglobulinemia (HP:0003139)2.53253930
42Pulmonary infiltrates (HP:0002113)2.52679634
43Arterial thrombosis (HP:0004420)2.51058726
44Spontaneous hematomas (HP:0007420)2.50262672
45Papillary thyroid carcinoma (HP:0002895)2.49221358
46Optic neuritis (HP:0100653)2.49212878
47Retrobulbar optic neuritis (HP:0100654)2.49212878
48Eczematoid dermatitis (HP:0000976)2.48559479
49Congenital stationary night blindness (HP:0007642)2.45462101
50Hematochezia (HP:0002573)2.44959666
51Agammaglobulinemia (HP:0004432)2.43610665
52Symptomatic seizures (HP:0011145)2.42217962
53Meningitis (HP:0001287)2.41398792
54Chronic diarrhea (HP:0002028)2.40175359
55Macroorchidism (HP:0000053)2.39664267
56Autoimmune thrombocytopenia (HP:0001973)2.39179978
57B lymphocytopenia (HP:0010976)2.38876122
58Abnormality of B cell number (HP:0010975)2.38876122
59Hypoglycemic coma (HP:0001325)2.35921778
60Metaphyseal dysplasia (HP:0100255)2.35052796
61Severe combined immunodeficiency (HP:0004430)2.34791231
62Granulocytopenia (HP:0001913)2.33764878
63Inflammation of the large intestine (HP:0002037)2.32855243
64Recurrent cutaneous fungal infections (HP:0011370)2.30701458
65Chronic mucocutaneous candidiasis (HP:0002728)2.30701458
66Abnormality of the renal cortex (HP:0011035)2.30679485
67Orchitis (HP:0100796)2.27760248
68Prostate neoplasm (HP:0100787)2.27544350
69Gastrointestinal inflammation (HP:0004386)2.25383192
70Decreased circulating renin level (HP:0003351)2.24976561
71Chronic otitis media (HP:0000389)2.21685917
72Recurrent skin infections (HP:0001581)2.21258530
73Hypoplasia of the thymus (HP:0000778)2.19420994
74Fatigue (HP:0012378)2.17093708
75Disinhibition (HP:0000734)2.14350726
76Gingival bleeding (HP:0000225)2.13983859
77Combined immunodeficiency (HP:0005387)2.11455124
78Thickened calvaria (HP:0002684)2.11306108
79Abnormality of lateral ventricle (HP:0030047)2.11270313
80Keratoconjunctivitis sicca (HP:0001097)2.11224257
81Lymphopenia (HP:0001888)2.10142074
82Abnormality of the axillary hair (HP:0100134)2.10019296
83Abnormality of secondary sexual hair (HP:0009888)2.10019296
84Neoplasm of the tracheobronchial system (HP:0100552)2.03861185
85Cellulitis (HP:0100658)2.02938255
86Autoimmune hemolytic anemia (HP:0001890)2.02692995
87Absent frontal sinuses (HP:0002688)2.02335257
88Truncal obesity (HP:0001956)2.02184275
89Limb hypertonia (HP:0002509)2.01698258
90Gaze-evoked nystagmus (HP:0000640)2.01517730
91Febrile seizures (HP:0002373)2.00966718
92Bronchitis (HP:0012387)2.00726538
93Metabolic alkalosis (HP:0200114)1.99485121
94Hyperventilation (HP:0002883)1.97474414
95Late onset (HP:0003584)1.96973643
96Vasculitis (HP:0002633)1.95658900
97Encephalitis (HP:0002383)1.95036165
98Periodontitis (HP:0000704)1.95018594
99Long eyelashes (HP:0000527)1.93934077
100Abnormality of cells of the lymphoid lineage (HP:0012140)1.93439280
101Viral hepatitis (HP:0006562)1.93406349
102IgA deficiency (HP:0002720)1.92891141
103Gastrointestinal infarctions (HP:0005244)1.92485218
104Increased IgM level (HP:0003496)1.91921913
105IgG deficiency (HP:0004315)1.90993384
106Alveolar cell carcinoma (HP:0006519)1.89932142
107Hemiplegia (HP:0002301)1.89754210
108Colitis (HP:0002583)1.89436105
109Keratoconjunctivitis (HP:0001096)1.89219978
110Chest pain (HP:0100749)1.88474329
111Abnormal rod and cone electroretinograms (HP:0008323)1.88450240
112Insulin resistance (HP:0000855)1.88080120
113Hypoproteinemia (HP:0003075)1.87458717
114Subacute progressive viral hepatitis (HP:0006572)1.86349202
115Hemoptysis (HP:0002105)1.86130398
116Epistaxis (HP:0000421)1.85057960
117Prolonged bleeding time (HP:0003010)1.83076616
118Renal cortical cysts (HP:0000803)1.82893570
119Clumsiness (HP:0002312)1.82105870
120Male infertility (HP:0003251)1.82085131
121Spinal cord lesions (HP:0100561)1.80649413
122Syringomyelia (HP:0003396)1.80649413
123Abnormality of eosinophils (HP:0001879)1.80165948
124Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.79644125
125Ureteral obstruction (HP:0006000)1.79443546
126Increased IgE level (HP:0003212)1.79023971
127Papilloma (HP:0012740)1.77718743
128Verrucae (HP:0200043)1.77718743
129Nasal polyposis (HP:0100582)1.77135616
130Leukocytosis (HP:0001974)1.76892189
131Hypoplastic labia majora (HP:0000059)1.76841135
132Joint swelling (HP:0001386)1.76012491
133Pulmonary embolism (HP:0002204)1.75148149
134Abnormality of the gastric mucosa (HP:0004295)1.73643987
135Recurrent sinusitis (HP:0011108)1.73632786
136Widely spaced teeth (HP:0000687)1.71290714
137Abnormality of the nasal septum (HP:0000419)1.69758288
138Chronic sinusitis (HP:0011109)1.65476536
139Neoplasm of the adrenal cortex (HP:0100641)1.65096215
140Chronic hepatic failure (HP:0100626)1.61078202
141Enlarged epiphyses (HP:0010580)1.59873352
142Hypoplastic iliac wings (HP:0002866)1.59430845
143Absent rod-and cone-mediated responses on ERG (HP:0007688)1.59393699
144Pancreatic cysts (HP:0001737)1.59253728
145Abolished electroretinogram (ERG) (HP:0000550)1.57400388

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK34.87257411
2FRK3.16143706
3MAP4K12.79722677
4TXK2.62960976
5LATS12.59882973
6JAK32.49085036
7NLK2.33919625
8HIPK22.26739104
9CAMKK22.19897782
10INSRR2.19224625
11TEC1.95750093
12ITK1.95586996
13EEF2K1.80800747
14STK101.75931654
15FES1.74071838
16CDK91.73891958
17FGFR31.72232735
18NUAK11.67753190
19MAP3K21.60379537
20TYK21.59006927
21MAP3K61.56658973
22RIPK41.56401731
23ZAP701.49497906
24IRAK41.45222695
25BMPR1B1.42237025
26MAPK151.41145856
27FLT31.40126822
28BTK1.36753731
29PIK3CG1.36655322
30FGFR21.33521679
31CDK61.32954822
32MAP3K131.32062865
33JAK11.31469968
34ACVR1B1.31248381
35AKT31.31090663
36MELK1.28423705
37PASK1.28122806
38IKBKE1.23749538
39ADRBK21.22760623
40STK31.21506845
41BMPR21.20669082
42MAP3K141.17568990
43CDC71.17533270
44JAK21.17413635
45EPHA31.16932527
46SGK4941.16811700
47SGK2231.16811700
48FGFR41.14662356
49MAP3K101.13126170
50CHUK1.12414432
51MARK31.12285407
52CAMKK11.11807676
53KIT1.09878294
54DMPK1.08679514
55CDK121.06948151
56NEK91.00098836
57CDK80.99663160
58PRKD20.99119736
59TNK20.95900747
60MST40.95419807
61IRAK30.94909395
62ERN10.94604190
63SYK0.92866231
64PIK3CA0.92106146
65TAOK10.90903128
66BRD40.87699992
67MAPK130.87045092
68MAP3K90.86927971
69PLK40.86570028
70GRK10.86379077
71PIM10.85409694
72TGFBR20.84931680
73BLK0.82074097
74LCK0.81805984
75STK240.80969543
76MAP4K20.80374596
77CSK0.78483339
78PRKCH0.77856283
79SIK20.76775094
80BRSK20.76487943
81MOS0.76419233
82WNK10.75246988
83TBK10.72772007
84MAP3K10.72710137
85IKBKB0.72670179
86NEK60.70412375
87CDK40.70369668
88RAF10.69639467
89RPS6KA40.69234200
90PDGFRB0.67011753
91TNIK0.66667353
92NTRK30.66573868
93PTK60.66532909
94SGK10.63617643
95TYRO30.62143568
96IRAK10.61159389
97RET0.60729672
98MAPK110.60266437
99HCK0.59634101
100NTRK20.59401017
101SGK30.58571108
102LRRK20.58061922
103STK110.58010195
104MAP3K30.57843335
105MAPK70.57699476
106STK390.57394968
107GRK70.57130551
108GRK60.57096016
109CSF1R0.57020971
110CASK0.56634348
111TRPM70.56440636
112WNK30.55966222
113SGK20.55587921
114TGFBR10.55498484
115DYRK1A0.55098146
116CDK30.52859827
117PTK2B0.52769651
118CAMK40.49717146
119MAP3K40.49183703
120PRKAA20.49100483
121MAP2K60.48142119
122MAP3K80.48072406
123STK40.47876228
124ADRBK10.47561842
125ATM0.46972981
126MAP3K50.46600868
127KSR20.46238346
128PRKCQ0.45863730
129MAPK120.45527591
130TRIB30.44982334
131LYN0.44461912
132RIPK10.44069564
133MARK20.43735053
134SIK30.43159168
135PDK10.42951361
136OXSR10.42362040
137ABL10.42035307
138RPS6KB10.40486300
139MAP3K70.39781165
140YES10.39654762
141MAP2K30.39530436
142ERBB40.38188527
143PKN20.37939127
144EGFR0.37356155

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.98626309
2Primary immunodeficiency_Homo sapiens_hsa053402.63775906
3T cell receptor signaling pathway_Homo sapiens_hsa046601.82969188
4Protein export_Homo sapiens_hsa030601.82927761
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.81820800
6B cell receptor signaling pathway_Homo sapiens_hsa046621.81303676
7Pancreatic cancer_Homo sapiens_hsa052121.76395798
8NF-kappa B signaling pathway_Homo sapiens_hsa040641.75921779
9Measles_Homo sapiens_hsa051621.73622956
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.73154482
11Leishmaniasis_Homo sapiens_hsa051401.60288773
12Osteoclast differentiation_Homo sapiens_hsa043801.56588000
13Antigen processing and presentation_Homo sapiens_hsa046121.54730699
14Jak-STAT signaling pathway_Homo sapiens_hsa046301.54698936
15Prolactin signaling pathway_Homo sapiens_hsa049171.51813355
16Chronic myeloid leukemia_Homo sapiens_hsa052201.51044623
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.46817813
18Asthma_Homo sapiens_hsa053101.46506985
19Herpes simplex infection_Homo sapiens_hsa051681.45368805
20Hematopoietic cell lineage_Homo sapiens_hsa046401.44347455
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.42262000
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.37962577
23Hepatitis B_Homo sapiens_hsa051611.37594902
24Cell cycle_Homo sapiens_hsa041101.33257334
25Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.32306874
26Non-homologous end-joining_Homo sapiens_hsa034501.31620591
27Circadian rhythm_Homo sapiens_hsa047101.29767129
28Toxoplasmosis_Homo sapiens_hsa051451.29311539
29Linoleic acid metabolism_Homo sapiens_hsa005911.24133904
30Acute myeloid leukemia_Homo sapiens_hsa052211.21813019
31Platelet activation_Homo sapiens_hsa046111.16287637
32Staphylococcus aureus infection_Homo sapiens_hsa051501.14044662
33Non-small cell lung cancer_Homo sapiens_hsa052231.12889403
34Thyroid cancer_Homo sapiens_hsa052161.12458934
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.11314998
36Phototransduction_Homo sapiens_hsa047441.11063042
37Ovarian steroidogenesis_Homo sapiens_hsa049131.10776735
38TNF signaling pathway_Homo sapiens_hsa046681.10009285
39RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.09782199
40Prostate cancer_Homo sapiens_hsa052151.08674290
41Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.08281297
42Dorso-ventral axis formation_Homo sapiens_hsa043201.07547763
43Type I diabetes mellitus_Homo sapiens_hsa049401.07169009
44FoxO signaling pathway_Homo sapiens_hsa040681.06136297
45Chemokine signaling pathway_Homo sapiens_hsa040621.05404826
46MicroRNAs in cancer_Homo sapiens_hsa052061.00451193
47Insulin resistance_Homo sapiens_hsa049311.00256944
48Influenza A_Homo sapiens_hsa051640.99823433
49Regulation of autophagy_Homo sapiens_hsa041400.98838997
50* RNA degradation_Homo sapiens_hsa030180.98495640
51Colorectal cancer_Homo sapiens_hsa052100.98368254
52NOD-like receptor signaling pathway_Homo sapiens_hsa046210.98110743
53Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97995547
54p53 signaling pathway_Homo sapiens_hsa041150.97132509
55Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96468337
56Lysine degradation_Homo sapiens_hsa003100.95366915
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93695325
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92816334
59Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91491865
60Other glycan degradation_Homo sapiens_hsa005110.91350349
61HTLV-I infection_Homo sapiens_hsa051660.90258517
62mTOR signaling pathway_Homo sapiens_hsa041500.90231062
63Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.90045336
64Small cell lung cancer_Homo sapiens_hsa052220.89917676
65Allograft rejection_Homo sapiens_hsa053300.89585583
66Adherens junction_Homo sapiens_hsa045200.88198625
67Type II diabetes mellitus_Homo sapiens_hsa049300.87885657
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.87187193
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84987299
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83908185
71Morphine addiction_Homo sapiens_hsa050320.83855187
72Endometrial cancer_Homo sapiens_hsa052130.83378336
73Renin secretion_Homo sapiens_hsa049240.81960188
74Ether lipid metabolism_Homo sapiens_hsa005650.81068850
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81006477
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.80267650
77Leukocyte transendothelial migration_Homo sapiens_hsa046700.79775385
78Apoptosis_Homo sapiens_hsa042100.78843242
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.78564624
80Olfactory transduction_Homo sapiens_hsa047400.77022252
81Cholinergic synapse_Homo sapiens_hsa047250.76887323
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76535769
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76482513
84Hepatitis C_Homo sapiens_hsa051600.76096913
85Graft-versus-host disease_Homo sapiens_hsa053320.75269442
86Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.74520083
87Notch signaling pathway_Homo sapiens_hsa043300.74504496
88Insulin secretion_Homo sapiens_hsa049110.72557432
89ABC transporters_Homo sapiens_hsa020100.72037343
90Viral carcinogenesis_Homo sapiens_hsa052030.71397199
91Choline metabolism in cancer_Homo sapiens_hsa052310.71317405
92Long-term potentiation_Homo sapiens_hsa047200.70985311
93Shigellosis_Homo sapiens_hsa051310.70129151
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70061121
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.68409693
96Serotonergic synapse_Homo sapiens_hsa047260.68153853
97Circadian entrainment_Homo sapiens_hsa047130.66874907
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66823253
99Ras signaling pathway_Homo sapiens_hsa040140.65476676
100Renal cell carcinoma_Homo sapiens_hsa052110.65269116
101Malaria_Homo sapiens_hsa051440.64973865
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63984529
103Nicotine addiction_Homo sapiens_hsa050330.63436007
104Basal transcription factors_Homo sapiens_hsa030220.63367216
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62455518
106Long-term depression_Homo sapiens_hsa047300.61941556
107AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.60773849
108Inositol phosphate metabolism_Homo sapiens_hsa005620.60310452
109Rheumatoid arthritis_Homo sapiens_hsa053230.59665919
110Tuberculosis_Homo sapiens_hsa051520.57907946
111Estrogen signaling pathway_Homo sapiens_hsa049150.57151271
112Taste transduction_Homo sapiens_hsa047420.56033394
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.55194788
114cAMP signaling pathway_Homo sapiens_hsa040240.54747309
115TGF-beta signaling pathway_Homo sapiens_hsa043500.54434343
116MAPK signaling pathway_Homo sapiens_hsa040100.53879289
117Oxytocin signaling pathway_Homo sapiens_hsa049210.53729218
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.53447285
119Glucagon signaling pathway_Homo sapiens_hsa049220.53170121
120Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51169188
121Glutamatergic synapse_Homo sapiens_hsa047240.50688449
122N-Glycan biosynthesis_Homo sapiens_hsa005100.50145088
123Glioma_Homo sapiens_hsa052140.49508600
124Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49449450
125Autoimmune thyroid disease_Homo sapiens_hsa053200.49413210
126Nitrogen metabolism_Homo sapiens_hsa009100.49191381
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.49136484
128VEGF signaling pathway_Homo sapiens_hsa043700.49009445
129Viral myocarditis_Homo sapiens_hsa054160.48881236
130Amphetamine addiction_Homo sapiens_hsa050310.47890979
131Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45939845
132Caffeine metabolism_Homo sapiens_hsa002320.45412901
133Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45089668
134GnRH signaling pathway_Homo sapiens_hsa049120.43309146
135mRNA surveillance pathway_Homo sapiens_hsa030150.41454865
136Thyroid hormone synthesis_Homo sapiens_hsa049180.39876653
137Pertussis_Homo sapiens_hsa051330.39526322

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