CNDP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1urate metabolic process (GO:0046415)5.70845126
2drug transmembrane transport (GO:0006855)4.73146679
3drug transport (GO:0015893)4.64890505
4NADH metabolic process (GO:0006734)4.64474746
5fat-soluble vitamin biosynthetic process (GO:0042362)4.40292375
6positive regulation by symbiont of host defense response (GO:0052509)4.37824466
7modulation by symbiont of host defense response (GO:0052031)4.37824466
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.37824466
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.37824466
10positive regulation by organism of defense response of other organism involved in symbiotic interact4.37824466
11modulation by symbiont of host immune response (GO:0052553)4.37824466
12aminoglycoside antibiotic metabolic process (GO:0030647)4.27449499
13epoxygenase P450 pathway (GO:0019373)4.25983579
14modified amino acid transport (GO:0072337)4.13136560
15glycosphingolipid catabolic process (GO:0046479)4.02315552
16interferon-gamma secretion (GO:0072643)3.84956254
17glycolipid catabolic process (GO:0019377)3.84258851
18cysteine metabolic process (GO:0006534)3.77110537
19regulation of interferon-beta biosynthetic process (GO:0045357)3.75072610
20organic cation transport (GO:0015695)3.67699639
21toxin transport (GO:1901998)3.66137838
22peptide catabolic process (GO:0043171)3.63989845
23drug catabolic process (GO:0042737)3.61637970
24neutrophil activation involved in immune response (GO:0002283)3.61067085
25oligosaccharide catabolic process (GO:0009313)3.59851682
26macrophage activation involved in immune response (GO:0002281)3.54562906
27respiratory burst (GO:0045730)3.49474937
28folic acid transport (GO:0015884)3.45435834
29phosphate ion transport (GO:0006817)3.44201498
30urea cycle (GO:0000050)3.43816977
31urea metabolic process (GO:0019627)3.43787253
32angiotensin maturation (GO:0002003)3.43466040
33positive regulation of interferon-alpha production (GO:0032727)3.43326215
34antigen processing and presentation via MHC class Ib (GO:0002475)3.43030562
35vitamin D metabolic process (GO:0042359)3.41510963
36glycoside metabolic process (GO:0016137)3.39564590
37low-density lipoprotein particle clearance (GO:0034383)3.38612087
38ceramide catabolic process (GO:0046514)3.37960750
39response to thyroid hormone (GO:0097066)3.36813896
40exogenous drug catabolic process (GO:0042738)3.30754018
41adhesion of symbiont to host (GO:0044406)3.29393821
42regulation of antigen processing and presentation (GO:0002577)3.28895974
43ethanol oxidation (GO:0006069)3.28702481
44lysine catabolic process (GO:0006554)3.28611244
45lysine metabolic process (GO:0006553)3.28611244
46regulation of cellular extravasation (GO:0002691)3.26339497
47regulation of interferon-alpha production (GO:0032647)3.21677015
48nitrogen cycle metabolic process (GO:0071941)3.19867827
49immunoglobulin mediated immune response (GO:0016064)3.16051749
50regulation of cholesterol storage (GO:0010885)3.15040444
51positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.14300420
52fructose metabolic process (GO:0006000)3.13388137
53sphingolipid catabolic process (GO:0030149)3.11804697
54folic acid metabolic process (GO:0046655)3.09197191
55tricarboxylic acid metabolic process (GO:0072350)3.05891504
56membrane lipid catabolic process (GO:0046466)3.05102514
57phosphate ion transmembrane transport (GO:0035435)3.04792099
58positive regulation of Cdc42 GTPase activity (GO:0043089)3.03779164
59ethanol metabolic process (GO:0006067)3.03405836
60type I interferon signaling pathway (GO:0060337)3.02346180
61cellular response to type I interferon (GO:0071357)3.02346180
62response to type I interferon (GO:0034340)3.00519321
63hydrogen peroxide biosynthetic process (GO:0050665)2.99419547
64vitamin transport (GO:0051180)2.98415537
65pinocytosis (GO:0006907)2.97666877
66intestinal absorption (GO:0050892)2.96560971
67glucuronate metabolic process (GO:0019585)2.96504922
68uronic acid metabolic process (GO:0006063)2.96504922
69regulation of vitamin metabolic process (GO:0030656)2.96334167
70antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.93440915
71pentose-phosphate shunt (GO:0006098)2.92609136
72proline biosynthetic process (GO:0006561)2.92182054
73NADPH regeneration (GO:0006740)2.92093229
74drug metabolic process (GO:0017144)2.91417391
75proline metabolic process (GO:0006560)2.91266192
76Arp2/3 complex-mediated actin nucleation (GO:0034314)2.90193072
77NIK/NF-kappaB signaling (GO:0038061)2.89106316
78alpha-linolenic acid metabolic process (GO:0036109)2.88912954
79phospholipid efflux (GO:0033700)2.88624914
80interferon-gamma-mediated signaling pathway (GO:0060333)2.87729528
81cellular glucuronidation (GO:0052695)2.87183268
82amino sugar catabolic process (GO:0046348)2.87158393
83fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.86518837
84very-low-density lipoprotein particle assembly (GO:0034379)2.85054548
85response to peptidoglycan (GO:0032494)2.84380277
86response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.83024036
87response to host immune response (GO:0052572)2.83024036
88regulation of dendritic cell antigen processing and presentation (GO:0002604)2.83000212
89aldehyde catabolic process (GO:0046185)2.82203451
90glyoxylate metabolic process (GO:0046487)2.82146845
91complement activation, classical pathway (GO:0006958)2.81981620
92amyloid precursor protein catabolic process (GO:0042987)2.81057868
93regulation of cholesterol esterification (GO:0010872)2.77772647
94apoptotic cell clearance (GO:0043277)2.75121803
95glutamine family amino acid biosynthetic process (GO:0009084)2.73602936
96positive regulation of cellular amine metabolic process (GO:0033240)2.72982615
97primary alcohol catabolic process (GO:0034310)2.72268748
98vitamin transmembrane transport (GO:0035461)2.71038761
99excretion (GO:0007588)2.69123921
100quaternary ammonium group transport (GO:0015697)2.67938017
101phagosome maturation (GO:0090382)2.67790140
102basic amino acid transport (GO:0015802)2.66364612
103L-alpha-amino acid transmembrane transport (GO:1902475)2.66154431
104positive regulation of chemokine biosynthetic process (GO:0045080)2.65546134
105lipoprotein transport (GO:0042953)2.64010570
106plasma lipoprotein particle assembly (GO:0034377)2.63868112
107sexual reproduction (GO:0019953)2.61616658
108reactive oxygen species biosynthetic process (GO:1903409)2.60387817
109natural killer cell mediated cytotoxicity (GO:0042267)2.59247070
110natural killer cell mediated immunity (GO:0002228)2.59247070
111amino-acid betaine metabolic process (GO:0006577)2.58928744
112renal absorption (GO:0070293)2.58813693
113positive regulation of triglyceride lipase activity (GO:0061365)2.58499887
114positive regulation of lipoprotein lipase activity (GO:0051006)2.58499887
115detection of bacterium (GO:0016045)2.57807257
116positive regulation of interferon-beta production (GO:0032728)2.57322471
117antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.57140650
118antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.57140650
119trivalent inorganic anion homeostasis (GO:0072506)2.56379255
120phosphate ion homeostasis (GO:0055062)2.56379255
121N-acetylneuraminate metabolic process (GO:0006054)2.55893619
122glycosylceramide metabolic process (GO:0006677)2.55839582
123response to growth hormone (GO:0060416)2.55700600
124L-ascorbic acid metabolic process (GO:0019852)2.55461157
125regulation of guanylate cyclase activity (GO:0031282)2.54656973
126regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.54522036
127regulation of podosome assembly (GO:0071801)2.54366978
128lipopolysaccharide-mediated signaling pathway (GO:0031663)2.54233277
129homocysteine metabolic process (GO:0050667)2.53796594
130hormone catabolic process (GO:0042447)2.53685020
131detection of other organism (GO:0098543)2.52727701
132serine family amino acid metabolic process (GO:0009069)2.52039154
133leukotriene metabolic process (GO:0006691)2.51986591
134regulation of early endosome to late endosome transport (GO:2000641)2.51986351
135oxaloacetate metabolic process (GO:0006107)2.50915030
136positive regulation of type 2 immune response (GO:0002830)2.50167664
137positive regulation of antigen processing and presentation (GO:0002579)2.50075890
138response to host (GO:0075136)2.49580085
139response to host defenses (GO:0052200)2.49580085
140response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.49580085
141protein-lipid complex assembly (GO:0065005)2.49459571
142calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.48476274
143complement activation (GO:0006956)2.47717021
144regulation of mononuclear cell migration (GO:0071675)2.47509939
145T-helper 1 type immune response (GO:0042088)2.46953749
146regulation of apoptotic cell clearance (GO:2000425)2.46018634
147B cell mediated immunity (GO:0019724)2.46008779
148positive regulation of cellular amide metabolic process (GO:0034250)2.45791931
149cellular response to interferon-gamma (GO:0071346)2.45658409
150wound healing, spreading of epidermal cells (GO:0035313)2.44812460
151hydrogen peroxide catabolic process (GO:0042744)2.44463472
152superoxide anion generation (GO:0042554)2.44373551
153NADP metabolic process (GO:0006739)2.44184075
154regulation of bile acid biosynthetic process (GO:0070857)2.44106095
155myeloid cell homeostasis (GO:0002262)2.43396480
156cellular response to thyroid hormone stimulus (GO:0097067)2.43309275
157glucose 6-phosphate metabolic process (GO:0051156)2.41083135
158transcytosis (GO:0045056)2.40987095
159negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.40986212
160positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.40799707
161granulocyte activation (GO:0036230)2.40512312
162regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.39777281
163cyclooxygenase pathway (GO:0019371)2.39168077
164cytokine secretion (GO:0050663)2.38804194
165lipoprotein metabolic process (GO:0042157)2.38754204
166adhesion of symbiont to host cell (GO:0044650)2.38628515
167virion attachment to host cell (GO:0019062)2.38628515
168positive regulation of leukocyte degranulation (GO:0043302)2.37530419
169protein localization to endosome (GO:0036010)2.37477276
170antigen processing and presentation of endogenous antigen (GO:0019883)2.37095308
171response to interferon-gamma (GO:0034341)2.36617091
172nucleoside diphosphate biosynthetic process (GO:0009133)2.34905728

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse4.18248241
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.59669485
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.69783970
4TP63_17297297_ChIP-ChIP_HaCaT_Human2.63906351
5IRF8_27001747_Chip-Seq_BMDM_Mouse2.61802809
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.61192639
7* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.46293932
8SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.36479973
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.35369575
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.29645665
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.29581015
12* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.29454512
13PPARA_22158963_ChIP-Seq_LIVER_Mouse2.17600146
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.16944909
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.12528887
16RXR_22158963_ChIP-Seq_LIVER_Mouse2.09101289
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.05947025
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.96624321
19TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.92869114
20* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.87817573
21STAT3_1855785_ChIP-Seq_MESCs_Mouse1.86955356
22* IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84250486
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.81232276
24EGR1_19374776_ChIP-ChIP_THP-1_Human1.76846375
25MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.72544876
26BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64581235
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62605421
28IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.60692899
29ESR1_21235772_ChIP-Seq_MCF-7_Human1.59044431
30HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.56961896
31PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.56480220
32POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.55660118
33SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.53063679
34NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52639227
35LXR_22158963_ChIP-Seq_LIVER_Mouse1.52054019
36* SPI1_23547873_ChIP-Seq_NB4_Human1.51640042
37TFEB_21752829_ChIP-Seq_HELA_Human1.50643941
38CLOCK_20551151_ChIP-Seq_293T_Human1.49235716
39SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.44535646
40NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.40395091
41AR_21909140_ChIP-Seq_LNCAP_Human1.39802071
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39166955
43KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37115337
44* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.32861358
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.32760261
46VDR_21846776_ChIP-Seq_THP-1_Human1.32339196
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.31471704
48TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.31333918
49RACK7_27058665_Chip-Seq_MCF-7_Human1.30780873
50CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.30009658
51GATA1_22383799_ChIP-Seq_G1ME_Mouse1.28189604
52TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27404176
53* SOX2_20726797_ChIP-Seq_SW620_Human1.26651336
54ESR2_21235772_ChIP-Seq_MCF-7_Human1.26175326
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23940981
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22862837
57* ATF3_27146783_Chip-Seq_COLON_Human1.21924866
58BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.21794934
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20058176
60RUNX1_22412390_ChIP-Seq_EML_Mouse1.19120950
61LXR_22292898_ChIP-Seq_THP-1_Human1.19106757
62GATA4_25053715_ChIP-Seq_YYC3_Human1.19041198
63SOX2_27498859_Chip-Seq_STOMACH_Mouse1.18498145
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17987592
65GATA1_19941827_ChIP-Seq_MEL_Mouse1.17882471
66SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17815049
67CDX2_20551321_ChIP-Seq_CACO-2_Human1.17426683
68SA1_27219007_Chip-Seq_Bcells_Human1.16413123
69E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14563406
70TCF7_22412390_ChIP-Seq_EML_Mouse1.14321142
71GATA6_25053715_ChIP-Seq_YYC3_Human1.14160737
72KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13269053
73THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.12635899
74RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.12290071
75ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12157725
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.12080016
77SA1_27219007_Chip-Seq_ERYTHROID_Human1.11999923
78SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11675034
79TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11524756
80ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10472596
81SMC4_20622854_ChIP-Seq_HELA_Human1.09977959
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.09939981
83ERG_21242973_ChIP-ChIP_JURKAT_Human1.09348308
84* MAF_26560356_Chip-Seq_TH1_Human1.09040766
85TRIM28_21343339_ChIP-Seq_HEK293_Human1.08854152
86PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08760768
87TCF3_18692474_ChIP-Seq_MEFs_Mouse1.08451827
88PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08030792
89BCL6_27268052_Chip-Seq_Bcells_Human1.06805285
90EGR1_23403033_ChIP-Seq_LIVER_Mouse1.05872279
91OCT4_18692474_ChIP-Seq_MEFs_Mouse1.05845807
92SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05579725
93KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.04715186
94EGR1_19032775_ChIP-ChIP_M12_Human1.04251703
95FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.04202839
96NANOG_18555785_ChIP-Seq_MESCs_Mouse1.03266540
97CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03178149
98CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.03131371
99VDR_24763502_ChIP-Seq_THP-1_Human1.02743883
100* TET1_21451524_ChIP-Seq_MESCs_Mouse1.02065939
101CREB1_26743006_Chip-Seq_LNCaP_Human1.01131421
102P68_20966046_ChIP-Seq_HELA_Human1.00786540
103CREB1_15753290_ChIP-ChIP_HEK293T_Human1.00743019
104KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00302739
105NANOG_18692474_ChIP-Seq_MEFs_Mouse0.99420667
106GATA1_19941826_ChIP-Seq_K562_Human0.99198958
107SALL4_18804426_ChIP-ChIP_XEN_Mouse0.99035188
108PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98777040
109SOX2_18692474_ChIP-Seq_MEFs_Mouse0.98271180
110CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97973969
111SPI1_23127762_ChIP-Seq_K562_Human0.96401874
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95805993
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95773118
114SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95473768
115HIF1A_21447827_ChIP-Seq_MCF-7_Human0.95339627
116MYB_26560356_Chip-Seq_TH2_Human0.94799408
117DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94556148
118PU_27001747_Chip-Seq_BMDM_Mouse0.94338675
119FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.94260476
120BCOR_27268052_Chip-Seq_Bcells_Human0.93375447
121UTX_26944678_Chip-Seq_JUKART_Human0.93148740
122ZFP281_18757296_ChIP-ChIP_E14_Mouse0.92900571
123TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.92559812
124EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.91729492
125MYC_22102868_ChIP-Seq_BL_Human0.91527912
126MYC_18555785_ChIP-Seq_MESCs_Mouse0.90923216
127KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90781550
128E2F1_18555785_ChIP-Seq_MESCs_Mouse0.90590777
129STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.89870662
130CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.89790545
131TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89727846
132ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.89468706
133SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89178689
134ZNF263_19887448_ChIP-Seq_K562_Human0.88192004

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.31906014
2MP0005360_urolithiasis4.26564326
3MP0009840_abnormal_foam_cell3.82168163
4MP0004019_abnormal_vitamin_homeostasis3.07559841
5MP0003436_decreased_susceptibility_to2.64567114
6MP0006082_CNS_inflammation2.58366892
7MP0003191_abnormal_cellular_cholesterol2.53094055
8MP0002139_abnormal_hepatobiliary_system2.42372444
9MP0003172_abnormal_lysosome_physiology2.39463325
10MP0005332_abnormal_amino_acid2.32323007
11MP0009643_abnormal_urine_homeostasis2.32258517
12MP0001835_abnormal_antigen_presentation2.31324463
13MP0003303_peritoneal_inflammation2.13332803
14MP0002136_abnormal_kidney_physiology1.93511377
15MP0002419_abnormal_innate_immunity1.93129123
16MP0009785_altered_susceptibility_to1.89837478
17MP0002138_abnormal_hepatobiliary_system1.85520422
18MP0003195_calcinosis1.82879904
19MP0001756_abnormal_urination1.81592791
20MP0003186_abnormal_redox_activity1.74894424
21MP0002148_abnormal_hypersensitivity_rea1.74627557
22MP0003705_abnormal_hypodermis_morpholog1.73140038
23MP0000604_amyloidosis1.72762800
24MP0004043_abnormal_pH_regulation1.71039505
25MP0005000_abnormal_immune_tolerance1.70782882
26MP0003879_abnormal_hair_cell1.69844190
27MP0005025_abnormal_response_to1.68689671
28MP0001958_emphysema1.62588519
29MP0008875_abnormal_xenobiotic_pharmacok1.62049521
30MP0010352_gastrointestinal_tract_polyps1.55768891
31MP0004947_skin_inflammation1.51695873
32MP0003329_amyloid_beta_deposits1.49572159
33MP0001765_abnormal_ion_homeostasis1.48526087
34MP0001533_abnormal_skeleton_physiology1.48069335
35MP0003724_increased_susceptibility_to1.46321621
36MP0008469_abnormal_protein_level1.45896106
37MP0002452_abnormal_antigen_presenting1.45786490
38MP0010234_abnormal_vibrissa_follicle1.45047841
39MP0004858_abnormal_nervous_system1.44251876
40MP0003300_gastrointestinal_ulcer1.43671880
41MP0009333_abnormal_splenocyte_physiolog1.43292243
42MP0001845_abnormal_inflammatory_respons1.40946184
43MP0005636_abnormal_mineral_homeostasis1.40278220
44MP0001666_abnormal_nutrient_absorption1.39133126
45MP0005464_abnormal_platelet_physiology1.37884335
46MP0003448_altered_tumor_morphology1.37555387
47MP0003806_abnormal_nucleotide_metabolis1.35967504
48MP0009764_decreased_sensitivity_to1.32256831
49MP0003566_abnormal_cell_adhesion1.31208253
50MP0005387_immune_system_phenotype1.29933981
51MP0001790_abnormal_immune_system1.29933981
52MP0003878_abnormal_ear_physiology1.28533041
53MP0005377_hearing/vestibular/ear_phenot1.28533041
54MP0001881_abnormal_mammary_gland1.28494706
55MP0005451_abnormal_body_composition1.27450901
56MP0002723_abnormal_immune_serum1.26749406
57MP0002254_reproductive_system_inflammat1.23459529
58MP0000343_altered_response_to1.23108889
59MP0005319_abnormal_enzyme/_coenzyme1.22411292
60MP0010155_abnormal_intestine_physiology1.20283660
61MP0001819_abnormal_immune_cell1.15191892
62MP0000920_abnormal_myelination1.12961221
63MP0008260_abnormal_autophagy1.12388562
64MP0001800_abnormal_humoral_immune1.11660485
65MP0002420_abnormal_adaptive_immunity1.11432125
66MP0004264_abnormal_extraembryonic_tissu1.11134991
67MP0005166_decreased_susceptibility_to1.10297381
68MP0010307_abnormal_tumor_latency1.10291023
69MP0002166_altered_tumor_susceptibility1.09962580
70MP0002998_abnormal_bone_remodeling1.08952615
71MP0005310_abnormal_salivary_gland1.08639370
72MP0000685_abnormal_immune_system1.07912690
73MP0000609_abnormal_liver_physiology1.06888112
74MP0002405_respiratory_system_inflammati1.04875658
75MP0010329_abnormal_lipoprotein_level1.04289821
76MP0000858_altered_metastatic_potential1.04177628
77MP0004782_abnormal_surfactant_physiolog1.03746159
78MP0003868_abnormal_feces_composition1.03300078
79MP0003075_altered_response_to1.03128477
80MP0001853_heart_inflammation1.02598684
81MP0005085_abnormal_gallbladder_physiolo1.01355103
82MP0001873_stomach_inflammation0.98098475
83MP0003866_abnormal_defecation0.97222773
84MP0005584_abnormal_enzyme/coenzyme_acti0.96511099
85MP0004147_increased_porphyrin_level0.96442780
86MP0003252_abnormal_bile_duct0.95763422
87MP0005167_abnormal_blood-brain_barrier0.94372887
88MP0005671_abnormal_response_to0.93693086
89MP0000490_abnormal_crypts_of0.92088954
90MP0001849_ear_inflammation0.91756149
91MP0003693_abnormal_embryo_hatching0.91712353
92MP0008004_abnormal_stomach_pH0.89748062
93MP0004510_myositis0.89582640
94MP0005365_abnormal_bile_salt0.89300447
95MP0002135_abnormal_kidney_morphology0.89218836
96MP0001663_abnormal_digestive_system0.87526348
97MP0000689_abnormal_spleen_morphology0.86993214
98MP0003690_abnormal_glial_cell0.85276758
99MP0000598_abnormal_liver_morphology0.84652369
100MP0002796_impaired_skin_barrier0.84164290
101MP0000716_abnormal_immune_system0.83220653
102MP0005023_abnormal_wound_healing0.82181403
103MP0009278_abnormal_bone_marrow0.81080375
104MP0003453_abnormal_keratinocyte_physiol0.81029857
105MP0003183_abnormal_peptide_metabolism0.80963306
106MP0001764_abnormal_homeostasis0.80939883
107MP0009379_abnormal_foot_pigmentation0.80415865
108MP0002722_abnormal_immune_system0.78534239
109MP0000678_abnormal_parathyroid_gland0.76611433
110MP0002429_abnormal_blood_cell0.76142362
111MP0000538_abnormal_urinary_bladder0.76087779
112MP0005409_darkened_coat_color0.74714487
113MP0000371_diluted_coat_color0.74568071
114MP0005165_increased_susceptibility_to0.74195304
115MP0002876_abnormal_thyroid_physiology0.73334247
116MP0009763_increased_sensitivity_to0.73106699
117MP0002118_abnormal_lipid_homeostasis0.72067390
118MP0003656_abnormal_erythrocyte_physiolo0.71638683
119MP0003795_abnormal_bone_structure0.70739372

Predicted human phenotypes

RankGene SetZ-score
1Vacuolated lymphocytes (HP:0001922)6.05978646
2Increased cerebral lipofuscin (HP:0011813)4.71263573
3Abnormality of macrophages (HP:0004311)4.52288511
4Gout (HP:0001997)4.08315287
5Systemic lupus erythematosus (HP:0002725)4.07800456
6Eczematoid dermatitis (HP:0000976)4.05227969
7Abnormality of glutamine family amino acid metabolism (HP:0010902)4.04852615
8Increased neuronal autofluorescent lipopigment (HP:0002074)4.02598795
9Dysostosis multiplex (HP:0000943)3.86551863
10Recurrent abscess formation (HP:0002722)3.82571395
11Abnormality of glycolipid metabolism (HP:0010969)3.73836259
12Abnormality of liposaccharide metabolism (HP:0010968)3.73836259
13Abnormality of glycosphingolipid metabolism (HP:0004343)3.73836259
14Nasal polyposis (HP:0100582)3.73458700
15Abnormality of monocarboxylic acid metabolism (HP:0010996)3.69407900
16Abnormality of the nasal mucosa (HP:0000433)3.64603066
17Chronic otitis media (HP:0000389)3.62098939
18Proximal tubulopathy (HP:0000114)3.59376324
19Autoimmune thrombocytopenia (HP:0001973)3.59020412
20Axonal loss (HP:0003447)3.54285756
21Recurrent bacterial skin infections (HP:0005406)3.46708548
22Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.42198556
23Complement deficiency (HP:0004431)3.37885321
24Recurrent gram-negative bacterial infections (HP:0005420)3.32270396
25Urinary glycosaminoglycan excretion (HP:0003541)3.29306190
26Mucopolysacchariduria (HP:0008155)3.29306190
27Hyperglycinuria (HP:0003108)3.29250394
28Abnormality of purine metabolism (HP:0004352)3.25700710
29Metabolic alkalosis (HP:0200114)3.24887662
30Abnormality of chloride homeostasis (HP:0011422)3.20740873
31Abnormality of proline metabolism (HP:0010907)3.12682704
32Hydroxyprolinuria (HP:0003080)3.12682704
33Hyperactive renin-angiotensin system (HP:0000841)3.12504792
34Hypokalemic alkalosis (HP:0001949)3.12419748
35Nausea (HP:0002018)3.09565681
36Abnormality of polysaccharide metabolism (HP:0011012)3.02845312
37Abnormality of glycosaminoglycan metabolism (HP:0004371)3.02845312
38Abnormality of mucopolysaccharide metabolism (HP:0011020)3.02845312
39Increased circulating renin level (HP:0000848)3.00537588
40Abnormality of complement system (HP:0005339)2.95074471
41Hypomagnesemia (HP:0002917)2.85370523
42Pustule (HP:0200039)2.80711307
43Interstitial pulmonary disease (HP:0006530)2.76359694
44Polyuria (HP:0000103)2.75555746
45Abnormality of magnesium homeostasis (HP:0004921)2.75534177
46Abnormality of renal excretion (HP:0011036)2.75435874
47Abnormal urine output (HP:0012590)2.74491330
48Increased purine levels (HP:0004368)2.73833567
49Hyperuricemia (HP:0002149)2.73833567
50Fat malabsorption (HP:0002630)2.66497116
51Abnormality of nucleobase metabolism (HP:0010932)2.64130427
52Chronic diarrhea (HP:0002028)2.63226109
53Glomerulonephritis (HP:0000099)2.61226079
54Tetany (HP:0001281)2.58461626
55Neurofibrillary tangles (HP:0002185)2.52388199
56Abnormality of serine family amino acid metabolism (HP:0010894)2.52105781
57Abnormality of glycine metabolism (HP:0010895)2.52105781
58Generalized aminoaciduria (HP:0002909)2.49866648
59Glycosuria (HP:0003076)2.47403689
60Abnormality of urine glucose concentration (HP:0011016)2.47403689
61Intrahepatic cholestasis (HP:0001406)2.43863438
62Gingivitis (HP:0000230)2.43742979
63Disinhibition (HP:0000734)2.40461410
64Gastrointestinal stroma tumor (HP:0100723)2.39136334
65Alkalosis (HP:0001948)2.35106167
66Widely patent fontanelles and sutures (HP:0004492)2.32489033
67Prolonged neonatal jaundice (HP:0006579)2.30748716
68Renal salt wasting (HP:0000127)2.28708892
69Xanthomatosis (HP:0000991)2.26571598
70Loss of speech (HP:0002371)2.25616710
71Metaphyseal cupping (HP:0003021)2.21893228
72Recurrent bronchitis (HP:0002837)2.21464245
73Agnosia (HP:0010524)2.18459766
74Malnutrition (HP:0004395)2.18250331
75Abnormal enzyme/coenzyme activity (HP:0012379)2.16532748
76Petechiae (HP:0000967)2.16155942
77Pathologic fracture (HP:0002756)2.15313230
78Hypobetalipoproteinemia (HP:0003563)2.14775370
79Progressive visual loss (HP:0000529)2.14496270
80Steatorrhea (HP:0002570)2.13837444
81Hypophosphatemia (HP:0002148)2.13702027
82Sensorimotor neuropathy (HP:0007141)2.13440084
83Abnormality of alkaline phosphatase activity (HP:0004379)2.13243790
84Myocardial infarction (HP:0001658)2.12953652
85Bronchitis (HP:0012387)2.11793520
86Cerebral inclusion bodies (HP:0100314)2.10649691
87Hemorrhage of the eye (HP:0011885)2.10532179
88Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.09738485
89Cervical subluxation (HP:0003308)2.08702146
90Bone pain (HP:0002653)2.05158823
91Vascular calcification (HP:0004934)2.04469722
92Chronic sinusitis (HP:0011109)2.02869233
93Hand muscle atrophy (HP:0009130)2.02498069
94Bilateral sensorineural hearing impairment (HP:0008619)2.02359076
95Delayed epiphyseal ossification (HP:0002663)2.01130502
96Nephrolithiasis (HP:0000787)2.00127206
97Thin bony cortex (HP:0002753)1.99958223
98Purpura (HP:0000979)1.99640597
99Segmental peripheral demyelination/remyelination (HP:0003481)1.98627762
100Chronic bronchitis (HP:0004469)1.97727011
101Recurrent sinusitis (HP:0011108)1.97218650
102Decreased circulating renin level (HP:0003351)1.96751080
103Colitis (HP:0002583)1.96682725
104Tetraparesis (HP:0002273)1.96666525
105Hyperphosphaturia (HP:0003109)1.96498447
106Nephritis (HP:0000123)1.96023129
107Abdominal distention (HP:0003270)1.96008514
108Ileus (HP:0002595)1.95043556
109Renal tubular acidosis (HP:0001947)1.94452957
110Recurrent fungal infections (HP:0002841)1.94245310
111Hepatosplenomegaly (HP:0001433)1.93865875
112Abnormality of the vasculature of the conjunctiva (HP:0008054)1.93752726
113Polygenic inheritance (HP:0010982)1.93108154
114Mediastinal lymphadenopathy (HP:0100721)1.92491505
115Peripheral demyelination (HP:0011096)1.92421190
116Flat acetabular roof (HP:0003180)1.92182882
117Protuberant abdomen (HP:0001538)1.90712332
118Esophageal varix (HP:0002040)1.90256621
119Global brain atrophy (HP:0002283)1.89234270
120Amyloidosis (HP:0011034)1.89157227
121Abnormality of small intestinal villus morphology (HP:0011472)1.87903236
122Villous atrophy (HP:0011473)1.87903236
123Bronchiectasis (HP:0002110)1.87221380
124Elevated alkaline phosphatase (HP:0003155)1.86329640
125Premature loss of primary teeth (HP:0006323)1.85870505
126Abnormality of vitamin metabolism (HP:0100508)1.85693936
127Thoracic kyphosis (HP:0002942)1.84740102
128Recurrent skin infections (HP:0001581)1.83778666
129Abnormality of renin-angiotensin system (HP:0000847)1.83502230
130Hyperparathyroidism (HP:0000843)1.83368218
131Personality changes (HP:0000751)1.83262530
132Vasculitis (HP:0002633)1.82902878
133Irritability (HP:0000737)1.82108004
134Emphysema (HP:0002097)1.81508990
135Orchitis (HP:0100796)1.81473685
136Dementia (HP:0000726)1.80836762
137Abnormality of the distal phalanges of the toes (HP:0010182)1.80657403
138Hypotension (HP:0002615)1.80505477
139Nuclear cataract (HP:0100018)1.80217162
140Polydipsia (HP:0001959)1.79672296
141Abnormal drinking behavior (HP:0030082)1.79672296
142Abnormality of fatty-acid metabolism (HP:0004359)1.79574171
143Focal segmental glomerulosclerosis (HP:0000097)1.79500590
144Abnormal urine phosphate concentration (HP:0012599)1.79359777
145Poor head control (HP:0002421)1.79170826
146Neuronal loss in central nervous system (HP:0002529)1.78429688
147Hyperammonemia (HP:0001987)1.77554470
148Elevated erythrocyte sedimentation rate (HP:0003565)1.77209095
149Increased serum ferritin (HP:0003281)1.74040546
150Meningitis (HP:0001287)1.73356886
151Abnormality of aromatic amino acid family metabolism (HP:0004338)1.70052812
152Progressive neurologic deterioration (HP:0002344)1.69882425

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.22569255
2EPHA23.07739874
3BLK3.06001688
4PBK2.96114989
5IRAK32.94034399
6ERN12.85814885
7WNK42.72121708
8ACVR1B2.71208411
9PRPF4B2.53164540
10MST42.51782427
11NME22.47732510
12TBK12.40823251
13TYK22.29263203
14MST1R2.22765953
15RIPK42.17616516
16MAP3K142.06078316
17WNK31.89660130
18TRIB31.88116099
19NEK11.87479679
20MAP4K11.86503429
21PIM21.86492202
22STK101.77393512
23PRKD31.68327935
24OXSR11.67462612
25EPHB11.65010654
26GRK61.63766524
27PAK41.62693307
28MAP3K31.60159512
29LRRK21.59762001
30CDC42BPA1.53385604
31MAP3K111.52111859
32SCYL21.47900930
33GRK71.46139523
34TESK21.42820015
35ZAP701.42378331
36KIT1.42271194
37ABL21.39864685
38FGFR41.34551522
39BUB11.32129049
40TGFBR21.29906343
41TESK11.24869153
42IRAK41.22648703
43NEK91.19805655
44MATK1.15222656
45BCKDK1.14755793
46PDK21.14388723
47BMX1.12183445
48IKBKB1.10378272
49MAP2K31.10039421
50MAP2K21.09398347
51RIPK11.07075603
52CSK1.05599026
53RPS6KA41.05165350
54PTK61.03787963
55WEE11.03682434
56EIF2AK11.01008888
57SIK11.00497142
58PIM10.98516491
59ICK0.97610060
60MAP3K80.97214956
61JAK10.92142273
62IKBKE0.91481266
63ARAF0.90300203
64FER0.86454239
65EEF2K0.85094288
66FGFR30.84293787
67JAK30.83899896
68TNK20.82730015
69ALK0.78975868
70PDK30.76938635
71PDK40.76938635
72MOS0.76265789
73FES0.74434273
74DAPK10.73788025
75PDK10.72864053
76KDR0.72662586
77STK38L0.72329390
78CSF1R0.71814482
79PKN20.70862140
80MET0.70367679
81TAOK20.67836187
82PRKCD0.67217168
83MAP2K60.66929206
84JAK20.66305885
85MARK30.65751933
86MAP3K100.64816611
87TIE10.62980698
88CDK120.62239602
89MAP3K130.61222613
90CHUK0.59765597
91PAK10.59382388
92PRKG20.59154736
93MAPKAPK30.57737757
94NEK20.55637909
95SYK0.55077143
96HCK0.54974253
97PTK20.54348712
98FGR0.53865086
99MAP3K50.52224436
100IRAK20.51719961
101GSK3A0.51180619
102IRAK10.49982410
103EGFR0.49164367
104SIK30.49137911
105LYN0.48885702
106MAPK110.48585592
107STK40.48023076
108MAPK150.47908828
109RPS6KA20.47760282
110LMTK20.46600375
111PDPK10.46473375
112LCK0.46242497
113PRKCI0.45807054
114MAP3K90.44319018
115TTK0.44267348
116CDK60.44053774
117SRC0.43372894
118STK30.43192226
119CAMKK20.42563354
120PIK3CG0.42461599
121KSR20.41639384
122BMPR20.41406032
123PRKD20.40428939
124DAPK30.39702280
125GRK50.39213254
126BTK0.38917177
127DAPK20.38518252
128DDR20.37153282
129NEK60.36477383
130FYN0.35562380
131TTN0.35481943
132MARK20.34432098
133ABL10.34424474
134CAMK1D0.34339043
135TAOK10.33326226
136MAP3K10.32664035
137EPHA30.29317850
138CDK40.29313009
139MAPKAPK20.29141181

Predicted pathways (KEGG)

RankGene SetZ-score
1Lysosome_Homo sapiens_hsa041423.06468365
2Other glycan degradation_Homo sapiens_hsa005112.98539512
3Pentose and glucuronate interconversions_Homo sapiens_hsa000402.52306394
4Mineral absorption_Homo sapiens_hsa049782.38603723
5Cyanoamino acid metabolism_Homo sapiens_hsa004602.33073129
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.32534028
7Vitamin digestion and absorption_Homo sapiens_hsa049772.23348124
8Collecting duct acid secretion_Homo sapiens_hsa049662.22783124
9Staphylococcus aureus infection_Homo sapiens_hsa051502.22456159
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.11293733
11* Histidine metabolism_Homo sapiens_hsa003402.05112783
12Renin-angiotensin system_Homo sapiens_hsa046142.03672387
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.03664503
14Allograft rejection_Homo sapiens_hsa053302.00127340
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.85455830
16Autoimmune thyroid disease_Homo sapiens_hsa053201.84084765
17Leishmaniasis_Homo sapiens_hsa051401.74134050
18Legionellosis_Homo sapiens_hsa051341.72738147
19Glutathione metabolism_Homo sapiens_hsa004801.71240605
20Fructose and mannose metabolism_Homo sapiens_hsa000511.66581944
21Phenylalanine metabolism_Homo sapiens_hsa003601.61405111
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.59940274
23Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.56298800
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.50795529
25Tuberculosis_Homo sapiens_hsa051521.50415003
26Pentose phosphate pathway_Homo sapiens_hsa000301.49601918
27Proteasome_Homo sapiens_hsa030501.48790272
28Type I diabetes mellitus_Homo sapiens_hsa049401.47105642
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.46954308
30Chemical carcinogenesis_Homo sapiens_hsa052041.45683417
31Phagosome_Homo sapiens_hsa041451.45342869
32Folate biosynthesis_Homo sapiens_hsa007901.44327678
33Rheumatoid arthritis_Homo sapiens_hsa053231.43010326
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.42107444
35Retinol metabolism_Homo sapiens_hsa008301.36112781
36Peroxisome_Homo sapiens_hsa041461.32024176
37Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.29393235
38Carbon metabolism_Homo sapiens_hsa012001.29323927
39Primary bile acid biosynthesis_Homo sapiens_hsa001201.26747688
40Pertussis_Homo sapiens_hsa051331.26620627
41Toll-like receptor signaling pathway_Homo sapiens_hsa046201.26301214
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.24537495
43Galactose metabolism_Homo sapiens_hsa000521.19105828
44Butanoate metabolism_Homo sapiens_hsa006501.18021350
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.16566883
46Caffeine metabolism_Homo sapiens_hsa002321.15989441
47Fat digestion and absorption_Homo sapiens_hsa049751.15677552
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10396532
49Antigen processing and presentation_Homo sapiens_hsa046121.10017560
50Osteoclast differentiation_Homo sapiens_hsa043801.07592114
51Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07168217
52Starch and sucrose metabolism_Homo sapiens_hsa005001.05303982
53Salmonella infection_Homo sapiens_hsa051321.02330500
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.01395724
55Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00384450
56Fatty acid degradation_Homo sapiens_hsa000710.98622371
57Tyrosine metabolism_Homo sapiens_hsa003500.95395024
58NF-kappa B signaling pathway_Homo sapiens_hsa040640.94813898
59Shigellosis_Homo sapiens_hsa051310.94545901
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.94259484
61Selenocompound metabolism_Homo sapiens_hsa004500.93110895
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.93020487
63Tryptophan metabolism_Homo sapiens_hsa003800.90868009
64Pyruvate metabolism_Homo sapiens_hsa006200.90380182
65PPAR signaling pathway_Homo sapiens_hsa033200.89204748
66Sphingolipid metabolism_Homo sapiens_hsa006000.89163258
67Arginine biosynthesis_Homo sapiens_hsa002200.88621046
68Glycerolipid metabolism_Homo sapiens_hsa005610.86598812
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.85519858
70Apoptosis_Homo sapiens_hsa042100.83764425
71Linoleic acid metabolism_Homo sapiens_hsa005910.83183633
72Steroid hormone biosynthesis_Homo sapiens_hsa001400.82884873
73Biosynthesis of amino acids_Homo sapiens_hsa012300.80517412
74Viral myocarditis_Homo sapiens_hsa054160.80068308
75Graft-versus-host disease_Homo sapiens_hsa053320.79950075
76Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79324381
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78822883
78Fatty acid biosynthesis_Homo sapiens_hsa000610.78404259
79Bile secretion_Homo sapiens_hsa049760.78032350
80Influenza A_Homo sapiens_hsa051640.76400604
81Propanoate metabolism_Homo sapiens_hsa006400.74898099
82RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.73816843
83Malaria_Homo sapiens_hsa051440.72674915
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71261958
85Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69771496
86Prion diseases_Homo sapiens_hsa050200.68912811
87* Arginine and proline metabolism_Homo sapiens_hsa003300.67736412
88Vibrio cholerae infection_Homo sapiens_hsa051100.66165477
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.66157244
90Protein digestion and absorption_Homo sapiens_hsa049740.65827530
91Measles_Homo sapiens_hsa051620.65717053
92Toxoplasmosis_Homo sapiens_hsa051450.64571360
93alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64088901
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63823407
95Hepatitis C_Homo sapiens_hsa051600.63102609
96Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.63038761
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62186304
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60828299
99Complement and coagulation cascades_Homo sapiens_hsa046100.60606308
100Herpes simplex infection_Homo sapiens_hsa051680.59747434
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.59664610
102Primary immunodeficiency_Homo sapiens_hsa053400.58179587
103Vitamin B6 metabolism_Homo sapiens_hsa007500.57238630
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56015080
105Regulation of autophagy_Homo sapiens_hsa041400.55731913
106B cell receptor signaling pathway_Homo sapiens_hsa046620.54672575
107Steroid biosynthesis_Homo sapiens_hsa001000.54083936
108Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54059390
109Sulfur metabolism_Homo sapiens_hsa009200.53313228
110* beta-Alanine metabolism_Homo sapiens_hsa004100.52798290
111Arachidonic acid metabolism_Homo sapiens_hsa005900.52689116
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50750466
113TNF signaling pathway_Homo sapiens_hsa046680.49217287
114Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.49139029
115Hematopoietic cell lineage_Homo sapiens_hsa046400.44598364
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.44222686
117Fatty acid metabolism_Homo sapiens_hsa012120.43858294
118Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42312871
119Amoebiasis_Homo sapiens_hsa051460.42286263
120ABC transporters_Homo sapiens_hsa020100.39941125
121Ether lipid metabolism_Homo sapiens_hsa005650.39920067
122Intestinal immune network for IgA production_Homo sapiens_hsa046720.38464253
123Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37411404
124Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36702136
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36105045
126Asthma_Homo sapiens_hsa053100.35095150
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.31100807
128Chemokine signaling pathway_Homo sapiens_hsa040620.30780422

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