CLEC3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)6.40772124
2cell migration involved in heart development (GO:0060973)4.71905462
3regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.46167384
4barbed-end actin filament capping (GO:0051016)4.42483474
5extracellular fibril organization (GO:0043206)4.36314091
6muscle filament sliding (GO:0030049)4.31982394
7actin-myosin filament sliding (GO:0033275)4.31982394
8keratan sulfate catabolic process (GO:0042340)4.30405221
9collagen fibril organization (GO:0030199)4.29459063
10negative regulation of cardiac muscle tissue growth (GO:0055022)4.27024056
11negative regulation of heart growth (GO:0061117)4.27024056
12regulation of skeletal muscle contraction (GO:0014819)4.25989384
13plasma membrane repair (GO:0001778)4.23757389
14regulation of sequestering of triglyceride (GO:0010889)4.20779210
15sarcomere organization (GO:0045214)4.19889712
16cardiac myofibril assembly (GO:0055003)4.16830873
17extracellular matrix assembly (GO:0085029)4.12273850
18skeletal muscle adaptation (GO:0043501)4.11458202
19carnitine shuttle (GO:0006853)4.06818959
20fatty acid transmembrane transport (GO:1902001)3.93841665
21myofibril assembly (GO:0030239)3.86768648
22endothelium development (GO:0003158)3.78584047
23collagen metabolic process (GO:0032963)3.76284830
24low-density lipoprotein particle clearance (GO:0034383)3.72814586
25adhesion of symbiont to host cell (GO:0044650)3.71440405
26virion attachment to host cell (GO:0019062)3.71440405
27transcytosis (GO:0045056)3.70703318
28fibril organization (GO:0097435)3.69855150
29multicellular organismal macromolecule metabolic process (GO:0044259)3.68559061
30ovulation from ovarian follicle (GO:0001542)3.67490165
31positive regulation of fatty acid oxidation (GO:0046321)3.63707591
32actin-mediated cell contraction (GO:0070252)3.63026377
33collagen catabolic process (GO:0030574)3.58381561
34lipid particle organization (GO:0034389)3.57106994
35positive regulation of receptor recycling (GO:0001921)3.54589072
36multicellular organismal metabolic process (GO:0044236)3.52849503
37regulation of p38MAPK cascade (GO:1900744)3.51858674
38multicellular organismal catabolic process (GO:0044243)3.38640343
39positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.35412528
40retina vasculature morphogenesis in camera-type eye (GO:0061299)3.34523209
41regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.33705147
42regulation of fatty acid oxidation (GO:0046320)3.32510059
43blood vessel maturation (GO:0001955)3.28815366
44positive regulation of fatty acid beta-oxidation (GO:0032000)3.25698544
45negative regulation of smooth muscle cell migration (GO:0014912)3.25416176
46adhesion of symbiont to host (GO:0044406)3.24873363
47bone trabecula formation (GO:0060346)3.20225247
48brown fat cell differentiation (GO:0050873)3.18880102
49negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.18213619
50endocrine hormone secretion (GO:0060986)3.17794186
51positive regulation of cellular amide metabolic process (GO:0034250)3.16913862
52epithelial cell-cell adhesion (GO:0090136)3.15692278
53peripheral nervous system axon ensheathment (GO:0032292)3.15315048
54myelination in peripheral nervous system (GO:0022011)3.15315048
55heart trabecula formation (GO:0060347)3.13958869
56carnitine transmembrane transport (GO:1902603)3.13408989
57hemidesmosome assembly (GO:0031581)3.10989228
58negative regulation of muscle hypertrophy (GO:0014741)3.10918208
59glomerular filtration (GO:0003094)3.10789647
60negative regulation of cardiac muscle hypertrophy (GO:0010614)3.10407596
61response to dietary excess (GO:0002021)3.08735978
62positive regulation of lipoprotein lipase activity (GO:0051006)3.08581881
63positive regulation of triglyceride lipase activity (GO:0061365)3.08581881
64negative regulation of granulocyte differentiation (GO:0030853)3.07741637
65positive regulation of vasculogenesis (GO:2001214)3.06910637
66positive regulation of p38MAPK cascade (GO:1900745)3.05862509
67ethanol oxidation (GO:0006069)3.03936749
68skin morphogenesis (GO:0043589)3.03798247
69white fat cell differentiation (GO:0050872)3.03241497
70extracellular matrix disassembly (GO:0022617)3.02702040
71bundle of His cell to Purkinje myocyte communication (GO:0086069)3.02661356
72growth hormone secretion (GO:0030252)3.02089897
73tricarboxylic acid cycle (GO:0006099)3.01793407
74negative regulation of stress fiber assembly (GO:0051497)3.01143066
75negative regulation of Rho protein signal transduction (GO:0035024)2.99701158
76vascular endothelial growth factor signaling pathway (GO:0038084)2.99646590
77negative regulation of platelet activation (GO:0010544)2.98961525
78trabecula formation (GO:0060343)2.98703197
79creatine metabolic process (GO:0006600)2.98647743
80basement membrane organization (GO:0071711)2.97172737
81actomyosin structure organization (GO:0031032)2.97164913
82glomerular basement membrane development (GO:0032836)2.96427070
83negative regulation of potassium ion transmembrane transport (GO:1901380)2.96241309
84peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.95497725
85negative regulation of cartilage development (GO:0061037)2.95314925
86type B pancreatic cell proliferation (GO:0044342)2.93084147
87regulation of integrin-mediated signaling pathway (GO:2001044)2.92863427
88oxygen transport (GO:0015671)2.91849266
89NADH metabolic process (GO:0006734)2.91567234
90triglyceride catabolic process (GO:0019433)2.91368245
91renal filtration (GO:0097205)2.90574567
92positive regulation of glycogen biosynthetic process (GO:0045725)2.90372804
93actin filament-based movement (GO:0030048)2.89553033
94cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.89245093
95protein localization to cell surface (GO:0034394)2.88831960
96cardiac muscle cell development (GO:0055013)2.87452328
97endothelial cell morphogenesis (GO:0001886)2.87346279
98cardiac muscle contraction (GO:0060048)2.86609452
99negative regulation of smooth muscle cell proliferation (GO:0048662)2.86204129
100valine metabolic process (GO:0006573)2.85513168
101striated muscle hypertrophy (GO:0014897)2.84839480
102negative regulation of nitric oxide biosynthetic process (GO:0045019)2.83987819
103negative regulation of homotypic cell-cell adhesion (GO:0034111)2.83266636
104amino-acid betaine transport (GO:0015838)2.82665558
105carnitine transport (GO:0015879)2.82665558
106apoptotic cell clearance (GO:0043277)2.82464963
107desmosome organization (GO:0002934)2.79569130
108angiogenesis involved in wound healing (GO:0060055)2.79005036
109cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.77606640
110venous blood vessel morphogenesis (GO:0048845)2.77449738
111glycerolipid catabolic process (GO:0046503)2.77113273
112regulation of cholesterol storage (GO:0010885)2.76942295
113biotin metabolic process (GO:0006768)2.74913668
114cardiac cell development (GO:0055006)2.74715649
115protein trimerization (GO:0070206)2.73865371
116negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.73312994
117cellular response to epinephrine stimulus (GO:0071872)2.72879492
118cGMP-mediated signaling (GO:0019934)2.72723410
119polyol transport (GO:0015791)2.72490375
120positive regulation of macrophage cytokine production (GO:0060907)2.70829393
121cellular response to vitamin (GO:0071295)2.70750565
122endodermal cell differentiation (GO:0035987)2.70450661
123regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.69183275
124complement activation, classical pathway (GO:0006958)2.67243172
125sequestering of extracellular ligand from receptor (GO:0035581)2.66993824
126ventricular cardiac muscle cell action potential (GO:0086005)2.66186586
127positive regulation of endothelial cell apoptotic process (GO:2000353)2.65285164
128complement activation, alternative pathway (GO:0006957)2.64728626
129complement activation (GO:0006956)2.63779276
130metanephric mesenchyme development (GO:0072075)2.63705801
131regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.63677613
132negative regulation of vascular permeability (GO:0043116)2.61459866
133regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.59949978
134positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.59628914
135lipid storage (GO:0019915)2.59337864
136peptide cross-linking (GO:0018149)2.58819732
137positive regulation of cholesterol efflux (GO:0010875)2.58523586
138regulation of cardiac muscle cell differentiation (GO:2000725)2.58449926
139stress fiber assembly (GO:0043149)2.58415865
140glycosaminoglycan catabolic process (GO:0006027)2.57979746
141muscle hypertrophy (GO:0014896)2.57011368
142neutral lipid catabolic process (GO:0046461)2.56998199
143acylglycerol catabolic process (GO:0046464)2.56998199
144sarcoplasmic reticulum calcium ion transport (GO:0070296)2.56133608
145striated muscle adaptation (GO:0014888)2.55615809
146negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.55224598
147cell-substrate junction assembly (GO:0007044)2.55030541
148negative regulation of cardiac muscle tissue development (GO:0055026)2.55028376
149fatty acid beta-oxidation (GO:0006635)2.54083472
150fatty acid homeostasis (GO:0055089)2.53566747
151positive regulation of macrophage derived foam cell differentiation (GO:0010744)2.51754390
152sulfur compound catabolic process (GO:0044273)2.50362529
153negative regulation of protein autophosphorylation (GO:0031953)2.49990782
154positive regulation of fat cell differentiation (GO:0045600)2.49374466
155regulation of macrophage derived foam cell differentiation (GO:0010743)2.48762568
156positive regulation of cellular response to insulin stimulus (GO:1900078)2.46910190
157keratan sulfate biosynthetic process (GO:0018146)2.46550256
158regulation of membrane protein ectodomain proteolysis (GO:0051043)2.46011424
159negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.45310465
160phagocytosis, recognition (GO:0006910)2.45082816
161regulation of macrophage chemotaxis (GO:0010758)2.43428884
162cAMP biosynthetic process (GO:0006171)2.42588931
163dermatan sulfate metabolic process (GO:0030205)2.38235674
164kidney mesenchyme development (GO:0072074)2.37445526
165ethanol metabolic process (GO:0006067)2.36540216
166negative regulation of nitric-oxide synthase activity (GO:0051001)2.36524370
167cell proliferation involved in metanephros development (GO:0072203)2.35488139
168dermatan sulfate biosynthetic process (GO:0030208)2.34966675
169regulation of vasculogenesis (GO:2001212)2.34922229
170positive regulation of glucose import (GO:0046326)2.34382131
171regulation of glucose import in response to insulin stimulus (GO:2001273)2.34043774
172UV protection (GO:0009650)2.33533338
173glial cell migration (GO:0008347)2.31756654
174chondroitin sulfate catabolic process (GO:0030207)2.31031712
175aminoglycan catabolic process (GO:0006026)2.30649662

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse6.49971612
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.02504328
3TP63_17297297_ChIP-ChIP_HaCaT_Human4.00653429
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.51687523
5CLOCK_20551151_ChIP-Seq_293T_Human3.40925411
6TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.96137059
7TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.55709477
8PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.52898265
9EP300_21415370_ChIP-Seq_HL-1_Mouse2.23108564
10ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.17566948
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.15243369
12TBX20_22328084_ChIP-Seq_HEART_Mouse2.05687342
13TBX20_22080862_ChIP-Seq_HEART_Mouse2.05687342
14MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.97600778
15ZNF263_19887448_ChIP-Seq_K562_Human1.96150250
16ESR1_21235772_ChIP-Seq_MCF-7_Human1.95206642
17RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.72321870
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.71866720
19FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.70293186
20CDX2_19796622_ChIP-Seq_MESCs_Mouse1.67475991
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.66064138
22* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.65933513
23EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.64744630
24ELK3_25401928_ChIP-Seq_HUVEC_Human1.64522281
25* CJUN_26792858_Chip-Seq_BT549_Human1.64108039
26BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.63287986
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.59352988
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.57826711
29KDM2B_26808549_Chip-Seq_SUP-B15_Human1.53105950
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.49193033
31HIF1A_21447827_ChIP-Seq_MCF-7_Human1.43448268
32ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.41501120
33* LXR_22292898_ChIP-Seq_THP-1_Human1.40814512
34PPAR_26484153_Chip-Seq_NCI-H1993_Human1.40417728
35SOX9_24532713_ChIP-Seq_HFSC_Mouse1.40218447
36GATA2_21666600_ChIP-Seq_HMVEC_Human1.40144566
37NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.39668477
38RAD21_21589869_ChIP-Seq_MESCs_Mouse1.39608920
39EZH2_18974828_ChIP-Seq_MESCs_Mouse1.39006259
40RNF2_18974828_ChIP-Seq_MESCs_Mouse1.39006259
41WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.35369947
42DROSHA_22980978_ChIP-Seq_HELA_Human1.35311064
43RACK7_27058665_Chip-Seq_MCF-7_Human1.34978396
44P63_26484246_Chip-Seq_KERATINOCYTES_Human1.32374060
45LXR_22158963_ChIP-Seq_LIVER_Mouse1.31124731
46SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.30173926
47GATA1_22025678_ChIP-Seq_K562_Human1.29514742
48SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.29137235
49STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27991972
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.27365694
51KDM2B_26808549_Chip-Seq_K562_Human1.26470906
52SA1_22415368_ChIP-Seq_MEFs_Mouse1.24979690
53SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.22929466
54RXR_22158963_ChIP-Seq_LIVER_Mouse1.22560095
55PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.21708169
56UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21599045
57CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.21070665
58FOXO3_23340844_ChIP-Seq_DLD1_Human1.19432927
59ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.19390522
60CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.19172476
61KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18303022
62PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.16572781
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.16412210
64PPARA_22158963_ChIP-Seq_LIVER_Mouse1.15189320
65KDM2B_26808549_Chip-Seq_DND41_Human1.13799678
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.11054579
67EED_16625203_ChIP-ChIP_MESCs_Mouse1.11043884
68EZH2_27304074_Chip-Seq_ESCs_Mouse1.10625486
69ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08608084
70SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08039073
71TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07776398
72MTF2_20144788_ChIP-Seq_MESCs_Mouse1.07432826
73AR_21572438_ChIP-Seq_LNCaP_Human1.07185635
74SMC1_22415368_ChIP-Seq_MEFs_Mouse1.06112568
75PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03555459
76TP63_22573176_ChIP-Seq_HFKS_Human1.02628845
77RUNX1_27514584_Chip-Seq_MCF-7_Human1.02203594
78CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01413261
79TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.00272759
80ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.00068090
81JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99975536
82SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.99808245
83* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98821344
84SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98676395
85SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98176109
86RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.97936344
87RNF2_27304074_Chip-Seq_ESCs_Mouse0.97173555
88SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97119171
89CTCF_27219007_Chip-Seq_Bcells_Human0.96853409
90SA1_27219007_Chip-Seq_ERYTHROID_Human0.96835760
91SUZ12_27294783_Chip-Seq_ESCs_Mouse0.96630110
92SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.96559428
93DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95310147
94* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95112384
95TP53_20018659_ChIP-ChIP_R1E_Mouse0.94971857
96MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94116202
97PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.93917504
98ATF3_27146783_Chip-Seq_COLON_Human0.93833512
99* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.93657429
100WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93639183
101PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.93467002
102* SMC4_20622854_ChIP-Seq_HELA_Human0.92899882
103NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92317623
104BP1_19119308_ChIP-ChIP_Hs578T_Human0.90141319
105UBF1/2_26484160_Chip-Seq_HMECs_Human0.89323113
106NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89208505
107TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.89186017
108SOX2_20726797_ChIP-Seq_SW620_Human0.88778328
109SMC3_22415368_ChIP-Seq_MEFs_Mouse0.87816190
110SA1_27219007_Chip-Seq_Bcells_Human0.87720773
111CTCF_27219007_Chip-Seq_ERYTHROID_Human0.87438889
112FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.87200153
113SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86614572
114ISL1_27105846_Chip-Seq_CPCs_Mouse0.86213500
115KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.85956573
116ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85949427
117KDM2B_26808549_Chip-Seq_JURKAT_Human0.85730183
118EZH2_27294783_Chip-Seq_ESCs_Mouse0.85689134
119SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.85573029
120SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.85573029
121IKZF1_21737484_ChIP-ChIP_HCT116_Human0.83873432
122TET1_21451524_ChIP-Seq_MESCs_Mouse0.82739833
123SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.82550265
124* CSB_26484114_Chip-Seq_FIBROBLAST_Human0.81832112
125NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81039558
126TP53_23651856_ChIP-Seq_MEFs_Mouse0.80332406
127TET1_21490601_ChIP-Seq_MESCs_Mouse0.78491706

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.92745285
2MP0005275_abnormal_skin_tensile6.18118994
3MP0005503_abnormal_tendon_morphology4.25213215
4MP0000751_myopathy4.12279055
5MP0002837_dystrophic_cardiac_calcinosis4.00590934
6MP0003705_abnormal_hypodermis_morpholog3.07242840
7MP0001958_emphysema2.96550729
8MP0004130_abnormal_muscle_cell2.59443251
9MP0004084_abnormal_cardiac_muscle2.52033017
10MP0003646_muscle_fatigue2.47488496
11MP0005670_abnormal_white_adipose2.47164244
12MP0004272_abnormal_basement_membrane2.35576035
13MP0000749_muscle_degeneration2.26212023
14MP0000750_abnormal_muscle_regeneration2.25779806
15MP0005666_abnormal_adipose_tissue2.21818875
16MP0004185_abnormal_adipocyte_glucose2.21760791
17MP0004036_abnormal_muscle_relaxation2.21238291
18MP0005330_cardiomyopathy2.07053775
19MP0002108_abnormal_muscle_morphology2.05008148
20MP0002060_abnormal_skin_morphology2.00724715
21MP0003279_aneurysm1.92771404
22MP0004087_abnormal_muscle_fiber1.91871921
23MP0005257_abnormal_intraocular_pressure1.81890453
24MP0004215_abnormal_myocardial_fiber1.78671614
25MP0005375_adipose_tissue_phenotype1.76469858
26MP0005620_abnormal_muscle_contractility1.69369955
27MP0002106_abnormal_muscle_physiology1.66689391
28MP0001542_abnormal_bone_strength1.66115990
29MP0000013_abnormal_adipose_tissue1.63462637
30MP0005369_muscle_phenotype1.61244887
31MP0005385_cardiovascular_system_phenoty1.57603068
32MP0001544_abnormal_cardiovascular_syste1.57603068
33MP0003566_abnormal_cell_adhesion1.55793752
34MP0006138_congestive_heart_failure1.54963702
35MP0000759_abnormal_skeletal_muscle1.54957227
36MP0004145_abnormal_muscle_electrophysio1.52913366
37MP0010368_abnormal_lymphatic_system1.52458630
38MP0002972_abnormal_cardiac_muscle1.48703663
39MP0006054_spinal_hemorrhage1.47740847
40MP0003329_amyloid_beta_deposits1.43328858
41MP0008775_abnormal_heart_ventricle1.39653921
42MP0000747_muscle_weakness1.37565202
43MP0003011_delayed_dark_adaptation1.29690076
44MP0000003_abnormal_adipose_tissue1.28865524
45MP0003828_pulmonary_edema1.28170017
46MP0010630_abnormal_cardiac_muscle1.27958740
47MP0001879_abnormal_lymphatic_vessel1.26887605
48MP0000343_altered_response_to1.25867146
49MP0002796_impaired_skin_barrier1.25345833
50MP0005508_abnormal_skeleton_morphology1.24122978
51MP0004484_altered_response_of1.18259714
52MP0005164_abnormal_response_to1.17012655
53MP0002269_muscular_atrophy1.14190831
54MP0002295_abnormal_pulmonary_circulatio1.13345440
55MP0002971_abnormal_brown_adipose1.12402856
56MP0001533_abnormal_skeleton_physiology1.07353300
57MP0000604_amyloidosis1.05952989
58MP0003950_abnormal_plasma_membrane1.04232597
59MP0002876_abnormal_thyroid_physiology1.04038912
60MP0010329_abnormal_lipoprotein_level1.03519249
61MP0003186_abnormal_redox_activity1.03353555
62MP0000733_abnormal_muscle_development1.02416524
63MP0001243_abnormal_dermal_layer1.01977320
64MP0004883_abnormal_blood_vessel0.97269604
65MP0005058_abnormal_lysosome_morphology0.96705597
66MP0005623_abnormal_meninges_morphology0.96060018
67MP0010030_abnormal_orbit_morphology0.95308263
68MP0003959_abnormal_lean_body0.94846963
69MP0000579_abnormal_nail_morphology0.93560072
70MP0005535_abnormal_body_temperature0.93281131
71MP0003690_abnormal_glial_cell0.90941007
72MP0002166_altered_tumor_susceptibility0.90302022
73MP0003091_abnormal_cell_migration0.87707557
74MP0004858_abnormal_nervous_system0.87003191
75MP0003137_abnormal_impulse_conducting0.85587020
76MP0009115_abnormal_fat_cell0.85082546
77MP0000767_abnormal_smooth_muscle0.82624025
78MP0003191_abnormal_cellular_cholesterol0.80108897
79MP0002234_abnormal_pharynx_morphology0.79524485
80* MP0000163_abnormal_cartilage_morphology0.79424333
81MP0002133_abnormal_respiratory_system0.78805432
82MP0005388_respiratory_system_phenotype0.78805432
83MP0003724_increased_susceptibility_to0.78541875
84MP0003075_altered_response_to0.77752238
85MP0003045_fibrosis0.77447467
86MP0004085_abnormal_heartbeat0.77076964
87MP0002896_abnormal_bone_mineralization0.76923147
88MP0005023_abnormal_wound_healing0.75888256
89MP0010386_abnormal_urinary_bladder0.75368290
90MP0005367_renal/urinary_system_phenotyp0.75155317
91MP0000516_abnormal_urinary_system0.75155317
92MP0005165_increased_susceptibility_to0.74119151
93MP0002127_abnormal_cardiovascular_syste0.73937071
94MP0005595_abnormal_vascular_smooth0.72305381
95MP0002006_tumorigenesis0.72041521
96MP0000534_abnormal_ureter_morphology0.71822945
97MP0005334_abnormal_fat_pad0.71460012
98MP0002128_abnormal_blood_circulation0.70829341
99MP0009780_abnormal_chondrocyte_physiolo0.69802596
100MP0003221_abnormal_cardiomyocyte_apopto0.69474635
101MP0002933_joint_inflammation0.69259587
102MP0001614_abnormal_blood_vessel0.68195571
103MP0010771_integument_phenotype0.68137666
104MP0002118_abnormal_lipid_homeostasis0.67975490
105MP0005390_skeleton_phenotype0.67638712
106MP0000266_abnormal_heart_morphology0.67449040
107MP0002115_abnormal_skeleton_extremities0.66894913
108MP0004510_myositis0.66893175
109MP0009840_abnormal_foam_cell0.65296429
110MP0004233_abnormal_muscle_weight0.65016294
111MP0005167_abnormal_blood-brain_barrier0.63279383
112MP0002332_abnormal_exercise_endurance0.61226119
113MP0000249_abnormal_blood_vessel0.60733188
114MP0008961_abnormal_basal_metabolism0.60461442
115MP0000230_abnormal_systemic_arterial0.60398890
116MP0002970_abnormal_white_adipose0.60027144
117MP0001756_abnormal_urination0.58873186
118MP0002249_abnormal_larynx_morphology0.58820546
119MP0002998_abnormal_bone_remodeling0.58145005
120MP0001661_extended_life_span0.57172638
121MP0009384_cardiac_valve_regurgitation0.56917029
122MP0009250_abnormal_appendicular_skeleto0.56297760
123MP0005501_abnormal_skin_physiology0.56191200
124MP0002254_reproductive_system_inflammat0.56139352
125MP0005448_abnormal_energy_balance0.53417520
126MP0005452_abnormal_adipose_tissue0.53349851
127MP0000858_altered_metastatic_potential0.53072945
128MP0005647_abnormal_sex_gland0.53046975

Predicted human phenotypes

RankGene SetZ-score
1Increased connective tissue (HP:0009025)6.57976603
2Type 1 muscle fiber predominance (HP:0003803)6.06916164
3Muscle fiber splitting (HP:0003555)5.90798684
4Ankle contracture (HP:0006466)5.52684389
5Protrusio acetabuli (HP:0003179)5.29175072
6Broad metatarsal (HP:0001783)5.01028831
7Systemic lupus erythematosus (HP:0002725)4.68787990
8Premature rupture of membranes (HP:0001788)4.50708382
9Increased variability in muscle fiber diameter (HP:0003557)4.49533608
10Abnormality of complement system (HP:0005339)4.41080659
11Follicular hyperkeratosis (HP:0007502)4.36053079
12Vascular tortuosity (HP:0004948)4.11636854
13Abnormality of skeletal muscle fiber size (HP:0012084)4.09068937
14Spinal rigidity (HP:0003306)4.06554733
15Aortic dissection (HP:0002647)3.94513128
16Exercise-induced myalgia (HP:0003738)3.90553729
17Slender build (HP:0001533)3.80965065
18Hyporeflexia of lower limbs (HP:0002600)3.76883774
19Sudden death (HP:0001699)3.71671056
20Mildly elevated creatine phosphokinase (HP:0008180)3.66231576
21Right ventricular cardiomyopathy (HP:0011663)3.66089615
22Cerebral aneurysm (HP:0004944)3.65942511
23Difficulty running (HP:0009046)3.53769511
24Ventricular tachycardia (HP:0004756)3.52711764
25Joint stiffness (HP:0001387)3.49444045
26Exercise-induced muscle cramps (HP:0003710)3.49391904
27Round ear (HP:0100830)3.44066296
28Aortic aneurysm (HP:0004942)3.30396057
29Calf muscle hypertrophy (HP:0008981)3.27975364
30Soft skin (HP:0000977)3.21572462
31Lipoatrophy (HP:0100578)3.14995956
32Shallow orbits (HP:0000586)3.10903843
33Muscle hypertrophy of the lower extremities (HP:0008968)3.10322720
34Myoglobinuria (HP:0002913)2.99761118
35Atrophic scars (HP:0001075)2.98974074
36Abnormality of the calf musculature (HP:0001430)2.98687342
37Wrist flexion contracture (HP:0001239)2.97751625
38Bladder diverticulum (HP:0000015)2.91729637
39Myotonia (HP:0002486)2.91261317
40Mitral valve prolapse (HP:0001634)2.91016989
41Fragile skin (HP:0001030)2.86354023
42Aortic valve stenosis (HP:0001650)2.80266127
43Striae distensae (HP:0001065)2.78528705
44Hypertriglyceridemia (HP:0002155)2.78164417
45Dilatation of the ascending aorta (HP:0005111)2.76397440
46Arterial tortuosity (HP:0005116)2.74019956
47Emphysema (HP:0002097)2.72675595
48Pulmonary artery stenosis (HP:0004415)2.71585289
49Polycythemia (HP:0001901)2.69192707
50Genu recurvatum (HP:0002816)2.68158698
51Glomerulonephritis (HP:0000099)2.64912850
52Atrial fibrillation (HP:0005110)2.62170252
53Rectal prolapse (HP:0002035)2.59906333
54EMG: myopathic abnormalities (HP:0003458)2.52066151
55Biconcave vertebral bodies (HP:0004586)2.50927761
56Asymmetric septal hypertrophy (HP:0001670)2.50234452
57Muscle fiber inclusion bodies (HP:0100299)2.48016692
58Ectopia lentis (HP:0001083)2.42118229
59Primary atrial arrhythmia (HP:0001692)2.41692242
60Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.41392141
61Cervical subluxation (HP:0003308)2.39307928
62Acanthosis nigricans (HP:0000956)2.36309070
63Nephritis (HP:0000123)2.35488400
64Supraventricular arrhythmia (HP:0005115)2.34631414
65Mitral regurgitation (HP:0001653)2.31449575
66Supraventricular tachycardia (HP:0004755)2.29532796
67Flat cornea (HP:0007720)2.28957187
68Nuclear cataract (HP:0100018)2.28463823
69Subaortic stenosis (HP:0001682)2.28463738
70Abnormality of the left ventricular outflow tract (HP:0011103)2.28463738
71Difficulty climbing stairs (HP:0003551)2.28444669
72Generalized amyotrophy (HP:0003700)2.28425330
73Overgrowth (HP:0001548)2.26539278
74Limb-girdle muscle weakness (HP:0003325)2.24847446
75Reduced subcutaneous adipose tissue (HP:0003758)2.22975168
76Venous abnormality (HP:0002624)2.22304007
77Hyperextensible skin (HP:0000974)2.20309028
78Aneurysm (HP:0002617)2.19960450
79Obstructive sleep apnea (HP:0002870)2.19672113
80Mitral stenosis (HP:0001718)2.19576623
81Muscle stiffness (HP:0003552)2.19408978
82Facial diplegia (HP:0001349)2.16212697
83Ovoid vertebral bodies (HP:0003300)2.14695190
84Neck muscle weakness (HP:0000467)2.13061230
85Amyloidosis (HP:0011034)2.12522383
86Venous insufficiency (HP:0005293)2.12106334
87Rhabdomyolysis (HP:0003201)2.11327989
88Neonatal short-limb short stature (HP:0008921)2.11079037
89Bowel diverticulosis (HP:0005222)2.10603381
90Distal lower limb muscle weakness (HP:0009053)2.10335710
91Dilated cardiomyopathy (HP:0001644)2.10110420
92Proximal amyotrophy (HP:0007126)2.09158460
93Beaking of vertebral bodies (HP:0004568)2.09067761
94Complement deficiency (HP:0004431)2.07062125
95Patent foramen ovale (HP:0001655)2.06502974
96Axonal loss (HP:0003447)2.05018187
97Bundle branch block (HP:0011710)2.03406715
98Broad ribs (HP:0000885)2.01757457
99Spontaneous hematomas (HP:0007420)2.01476614
100Mild short stature (HP:0003502)2.01235117
101Nemaline bodies (HP:0003798)2.00891956
102Limited hip movement (HP:0008800)2.00066320
103Bronchomalacia (HP:0002780)1.99934691
104Joint laxity (HP:0001388)1.98327685
105Wormian bones (HP:0002645)1.97993774
106Spinal cord compression (HP:0002176)1.97465542
107Scapular winging (HP:0003691)1.95946723
108Elbow flexion contracture (HP:0002987)1.95287751
109Hyperlipoproteinemia (HP:0010980)1.95069262
110Bone cyst (HP:0012062)1.94161824
111Peritonitis (HP:0002586)1.93588088
112Lymphangioma (HP:0100764)1.91338184
113Distal arthrogryposis (HP:0005684)1.91329507
114Palpitations (HP:0001962)1.90494359
115Hip contracture (HP:0003273)1.89518182
116Conjunctival hamartoma (HP:0100780)1.88759399
117Blue sclerae (HP:0000592)1.86513288
118Insulin resistance (HP:0000855)1.85391473
119Osteolytic defects of the phalanges of the hand (HP:0009771)1.84658838
120Osteolytic defects of the hand bones (HP:0009699)1.84658838
121Ventricular arrhythmia (HP:0004308)1.82767351
122Prolonged QT interval (HP:0001657)1.82476688
123Growth hormone excess (HP:0000845)1.82432138
124Redundant skin (HP:0001582)1.82394659
125Spondylolisthesis (HP:0003302)1.81588194
126Abnormal delivery (HP:0001787)1.80135717
127Oligomenorrhea (HP:0000876)1.79083353
128Abnormal atrioventricular conduction (HP:0005150)1.76729873
129Achilles tendon contracture (HP:0001771)1.75685806
130Mesangial abnormality (HP:0001966)1.75248548
131Wide anterior fontanel (HP:0000260)1.74845342
132Coxa vara (HP:0002812)1.74254043
133Back pain (HP:0003418)1.74238244
134Testicular atrophy (HP:0000029)1.73727698
135Limb-girdle muscle atrophy (HP:0003797)1.72399531
136Ulnar deviation of the wrist (HP:0003049)1.72314297
137Infantile muscular hypotonia (HP:0008947)1.72239629
138Hypoplasia of the iris (HP:0007676)1.71987173
139Atrioventricular block (HP:0001678)1.71244173
140Abnormality of dentin (HP:0010299)1.70944972
141Osteoarthritis (HP:0002758)1.70474526
142Abnormality of the 4th metacarpal (HP:0010012)1.69430106
143Small epiphyses (HP:0010585)1.69131386
144Aortic regurgitation (HP:0001659)1.68378178
145Hypercortisolism (HP:0001578)1.68245023
146Vertebral compression fractures (HP:0002953)1.68200640

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.58179328
2TRIB34.60741146
3MYLK3.24208351
4RIPK12.71236969
5SIK12.59613279
6LMTK22.58068297
7PHKG12.50070672
8PHKG22.50070672
9TESK12.41990575
10TIE12.37065710
11DMPK2.36591981
12DDR22.36484787
13ERN12.31413383
14TGFBR22.29829906
15OBSCN2.27568726
16PDK42.23910667
17PDK32.23910667
18PDGFRA2.13615738
19PKN22.05187190
20CAMK1D2.00714772
21EPHB21.95348123
22BCKDK1.94541736
23EPHB11.64673164
24CAMK1G1.54675719
25MST1R1.48172506
26ABL21.46776577
27KIT1.46740598
28ARAF1.44515644
29MOS1.41544626
30PRPF4B1.38773037
31PIK3CA1.38731687
32PDK21.38492323
33GRK51.38264307
34MAPK71.25845352
35FER1.24550860
36ILK1.22782569
37MAPKAPK31.21055581
38MAP2K31.20598594
39MAP3K31.10214148
40PINK11.09079748
41MAP3K71.08520386
42FGFR41.08355538
43PTK61.07115036
44PIK3CG1.02844327
45EPHA31.01674292
46PRKD11.01229747
47LATS10.99798588
48PRKG20.99677156
49MARK20.94628890
50INSRR0.94130346
51TBK10.93363062
52LATS20.92849720
53MAPK40.92585904
54TYK20.91164485
55PAK20.89657263
56ADRBK10.88832611
57TRPM70.87615546
58PRKAA20.84965386
59ROCK10.81625702
60PTK2B0.79770322
61MET0.79411167
62MAP3K130.79382049
63DAPK30.78062193
64EEF2K0.76079142
65PRKCH0.75994602
66MAPK120.74932750
67PDGFRB0.74637547
68LRRK20.74035968
69BMX0.73997012
70LIMK10.73362287
71FGFR30.72126578
72CSK0.71695372
73PIM20.68130133
74PRKD30.67016998
75BLK0.65615416
76FGFR20.63025023
77JAK10.62721485
78ZAP700.62448650
79STK240.61876313
80MAP2K10.60051704
81FES0.59956306
82MAP3K110.59881308
83HIPK20.59390903
84NME10.59359286
85ROCK20.57934854
86RET0.55363380
87NTRK10.54440665
88PRKG10.54322188
89PAK30.54101503
90ICK0.52129862
91PRKAA10.51966706
92GSK3A0.51224831
93PRKD20.51008544
94NEK10.50732681
95MAP3K60.50156799
96RPS6KA20.48764752
97CDC42BPA0.47806664
98JAK30.46799609
99NLK0.46055906
100KSR20.45978480
101MTOR0.45891801
102RPS6KL10.45164694
103RPS6KC10.45164694
104CAMK2G0.44258429
105TAOK10.44246085
106MAPK150.44189795
107DAPK20.43941121
108NEK90.43806675
109MARK10.43600003
110STK380.42426060
111JAK20.42319224
112RPS6KA60.41477033
113PTK20.41004366
114MAP2K20.40985700
115FGFR10.40461352
116PAK60.40289049
117MAPK30.40027588
118PAK40.39579375
119STK38L0.38738569
120WNK10.37505001
121TGFBR10.36507956
122PAK10.36206492
123PDPK10.35434596
124KDR0.31812701
125MAP3K10.31806320
126CAMK10.30637915
127CAMK40.30182464
128CAMK2D0.29297557
129PKN10.27677517
130FLT30.27232702
131PRKACG0.27055399
132SRC0.26858800
133MAP3K20.26655341
134MAPKAPK20.25882413

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.57553608
2ECM-receptor interaction_Homo sapiens_hsa045123.39603169
3Propanoate metabolism_Homo sapiens_hsa006402.64480725
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.59032710
5Dilated cardiomyopathy_Homo sapiens_hsa054142.58442409
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.52221933
7Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.46354437
8Protein digestion and absorption_Homo sapiens_hsa049742.38769300
9PPAR signaling pathway_Homo sapiens_hsa033202.32019936
10Focal adhesion_Homo sapiens_hsa045102.20196664
11Glycosaminoglycan degradation_Homo sapiens_hsa005312.12675037
12Fatty acid degradation_Homo sapiens_hsa000712.12496096
13Fatty acid metabolism_Homo sapiens_hsa012122.06689229
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.02740823
15Fatty acid biosynthesis_Homo sapiens_hsa000611.95376677
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.93184911
17Adipocytokine signaling pathway_Homo sapiens_hsa049201.73743069
18Cardiac muscle contraction_Homo sapiens_hsa042601.68672423
19Histidine metabolism_Homo sapiens_hsa003401.68496486
20Insulin resistance_Homo sapiens_hsa049311.61259379
21Other glycan degradation_Homo sapiens_hsa005111.56587861
22Amoebiasis_Homo sapiens_hsa051461.49357893
23Cyanoamino acid metabolism_Homo sapiens_hsa004601.44379059
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.38341993
25Viral myocarditis_Homo sapiens_hsa054161.31338920
26AMPK signaling pathway_Homo sapiens_hsa041521.30474250
27Carbon metabolism_Homo sapiens_hsa012001.30244097
28Pyruvate metabolism_Homo sapiens_hsa006201.28000536
29Renin-angiotensin system_Homo sapiens_hsa046141.26198595
30Insulin signaling pathway_Homo sapiens_hsa049101.18525686
31Caffeine metabolism_Homo sapiens_hsa002321.16023958
32Proteoglycans in cancer_Homo sapiens_hsa052051.13383474
33Arachidonic acid metabolism_Homo sapiens_hsa005901.09501345
34Vascular smooth muscle contraction_Homo sapiens_hsa042701.06387252
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.05100186
36Glycerolipid metabolism_Homo sapiens_hsa005611.03905227
37Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.02823711
38cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98948925
39beta-Alanine metabolism_Homo sapiens_hsa004100.95748012
40Malaria_Homo sapiens_hsa051440.94351615
41Renin secretion_Homo sapiens_hsa049240.93741985
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.92206541
43Glucagon signaling pathway_Homo sapiens_hsa049220.91786601
44Basal cell carcinoma_Homo sapiens_hsa052170.89890299
45Longevity regulating pathway - mammal_Homo sapiens_hsa042110.89347834
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89285891
47Ovarian steroidogenesis_Homo sapiens_hsa049130.87127521
48PI3K-Akt signaling pathway_Homo sapiens_hsa041510.86999595
49Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86898813
50Adherens junction_Homo sapiens_hsa045200.85394337
51Small cell lung cancer_Homo sapiens_hsa052220.82681468
52Toxoplasmosis_Homo sapiens_hsa051450.81030445
53Type II diabetes mellitus_Homo sapiens_hsa049300.79290339
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.78666072
55Starch and sucrose metabolism_Homo sapiens_hsa005000.77160317
56Platelet activation_Homo sapiens_hsa046110.76357460
57Fatty acid elongation_Homo sapiens_hsa000620.76275680
58Fat digestion and absorption_Homo sapiens_hsa049750.75310563
59Phagosome_Homo sapiens_hsa041450.73746422
60Phenylalanine metabolism_Homo sapiens_hsa003600.73475961
61Glutathione metabolism_Homo sapiens_hsa004800.72372392
62Bladder cancer_Homo sapiens_hsa052190.72111257
63Lysosome_Homo sapiens_hsa041420.72108061
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69949128
65Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69770135
66Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.68183479
67Oxytocin signaling pathway_Homo sapiens_hsa049210.68097947
68Tight junction_Homo sapiens_hsa045300.68085234
69HIF-1 signaling pathway_Homo sapiens_hsa040660.67665864
70Arginine biosynthesis_Homo sapiens_hsa002200.66064691
71Staphylococcus aureus infection_Homo sapiens_hsa051500.64787979
72Prion diseases_Homo sapiens_hsa050200.64751831
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.64504477
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.62707720
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61291830
76Complement and coagulation cascades_Homo sapiens_hsa046100.61198891
77Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.59884536
78Hedgehog signaling pathway_Homo sapiens_hsa043400.58832172
79VEGF signaling pathway_Homo sapiens_hsa043700.56816767
80Gastric acid secretion_Homo sapiens_hsa049710.56488836
81Nitrogen metabolism_Homo sapiens_hsa009100.56390550
82Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56357378
83Alzheimers disease_Homo sapiens_hsa050100.55991925
84Gap junction_Homo sapiens_hsa045400.55890026
85Butanoate metabolism_Homo sapiens_hsa006500.55701260
86Notch signaling pathway_Homo sapiens_hsa043300.54724721
87Lysine degradation_Homo sapiens_hsa003100.54659649
88Glycerophospholipid metabolism_Homo sapiens_hsa005640.54381861
89Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54289777
90Estrogen signaling pathway_Homo sapiens_hsa049150.53927423
91Arginine and proline metabolism_Homo sapiens_hsa003300.53426263
92Tryptophan metabolism_Homo sapiens_hsa003800.52250155
93cAMP signaling pathway_Homo sapiens_hsa040240.51507739
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.51460555
95Chemical carcinogenesis_Homo sapiens_hsa052040.51363901
96Calcium signaling pathway_Homo sapiens_hsa040200.49209325
97TGF-beta signaling pathway_Homo sapiens_hsa043500.49195859
98Acute myeloid leukemia_Homo sapiens_hsa052210.49083383
99GnRH signaling pathway_Homo sapiens_hsa049120.48753555
100Pathways in cancer_Homo sapiens_hsa052000.48638213
101Parkinsons disease_Homo sapiens_hsa050120.48107836
102Dorso-ventral axis formation_Homo sapiens_hsa043200.48102507
103Ras signaling pathway_Homo sapiens_hsa040140.48078498
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46045845
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43946341
106Retinol metabolism_Homo sapiens_hsa008300.43186084
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42947331
108Renal cell carcinoma_Homo sapiens_hsa052110.42604488
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41468525
110Endocytosis_Homo sapiens_hsa041440.41250806
111Bile secretion_Homo sapiens_hsa049760.41149351
112Melanogenesis_Homo sapiens_hsa049160.40468625
113Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39738267
114mTOR signaling pathway_Homo sapiens_hsa041500.39648330
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.39108992
116Aldosterone synthesis and secretion_Homo sapiens_hsa049250.37370651
117Hippo signaling pathway_Homo sapiens_hsa043900.37200362
118Chronic myeloid leukemia_Homo sapiens_hsa052200.37109877
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36150688
120Rap1 signaling pathway_Homo sapiens_hsa040150.34583523
121Circadian rhythm_Homo sapiens_hsa047100.34355272
122Primary bile acid biosynthesis_Homo sapiens_hsa001200.33522456
123Osteoclast differentiation_Homo sapiens_hsa043800.33331561
124Tyrosine metabolism_Homo sapiens_hsa003500.32440190
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32122606
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.31905835
127Axon guidance_Homo sapiens_hsa043600.31135783
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31113628
129Melanoma_Homo sapiens_hsa052180.31068220
130Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.30940473
131Pertussis_Homo sapiens_hsa051330.29830214
132Phospholipase D signaling pathway_Homo sapiens_hsa040720.29210322
133Cocaine addiction_Homo sapiens_hsa050300.27922923

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