CIART

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)4.90735186
2neurotransmitter-gated ion channel clustering (GO:0072578)4.55044637
3snRNA transcription (GO:0009301)4.16344834
4C4-dicarboxylate transport (GO:0015740)4.15751194
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.14476625
6lactate metabolic process (GO:0006089)4.10545377
7fatty acid homeostasis (GO:0055089)3.93248394
8presynaptic membrane assembly (GO:0097105)3.90189150
9neuronal action potential propagation (GO:0019227)3.88476943
10DNA methylation involved in gamete generation (GO:0043046)3.86935919
11regulation of meiosis I (GO:0060631)3.86109719
12NADH metabolic process (GO:0006734)3.82213327
13neuron cell-cell adhesion (GO:0007158)3.75163722
14mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.74087074
15mitochondrial respiratory chain complex I assembly (GO:0032981)3.74087074
16NADH dehydrogenase complex assembly (GO:0010257)3.74087074
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.65261672
18behavioral response to nicotine (GO:0035095)3.64456839
19presynaptic membrane organization (GO:0097090)3.61848381
20regulation of bile acid biosynthetic process (GO:0070857)3.58592626
21nonmotile primary cilium assembly (GO:0035058)3.52213873
22L-phenylalanine catabolic process (GO:0006559)3.52162657
23erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.52162657
24protein complex biogenesis (GO:0070271)3.51920134
25energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.50463118
26ATP hydrolysis coupled proton transport (GO:0015991)3.50463118
27L-serine metabolic process (GO:0006563)3.45539056
28locomotory exploration behavior (GO:0035641)3.45139201
29mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.41788613
30negative regulation of synaptic transmission, GABAergic (GO:0032229)3.38727303
31epithelial cilium movement (GO:0003351)3.33726050
32glutamate secretion (GO:0014047)3.30259962
33synapsis (GO:0007129)3.26892584
34positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.25623843
35synaptic transmission, glutamatergic (GO:0035249)3.25078146
36synaptic vesicle exocytosis (GO:0016079)3.23642210
37mitochondrial respiratory chain complex assembly (GO:0033108)3.21282725
38regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21126889
39epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.20102378
40synaptic vesicle docking involved in exocytosis (GO:0016081)3.19682428
41intraciliary transport (GO:0042073)3.18658986
42serine family amino acid catabolic process (GO:0009071)3.18404854
43ubiquinone biosynthetic process (GO:0006744)3.17187215
44ubiquinone metabolic process (GO:0006743)3.16021755
45ATP synthesis coupled proton transport (GO:0015986)3.15230803
46energy coupled proton transport, down electrochemical gradient (GO:0015985)3.15230803
47erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.13930576
48L-phenylalanine metabolic process (GO:0006558)3.13930576
49oxaloacetate metabolic process (GO:0006107)3.13854671
50cerebellar granule cell differentiation (GO:0021707)3.13027077
51vocalization behavior (GO:0071625)3.12869128
52transferrin transport (GO:0033572)3.12470669
53respiratory electron transport chain (GO:0022904)3.12351326
54male meiosis I (GO:0007141)3.11113982
55regulation of glutamate receptor signaling pathway (GO:1900449)3.10671016
56cholesterol catabolic process (GO:0006707)3.10457788
57sterol catabolic process (GO:0016127)3.10457788
58retinal cone cell development (GO:0046549)3.10136618
59neuron-neuron synaptic transmission (GO:0007270)3.08464430
60electron transport chain (GO:0022900)3.08147806
61glutamate receptor signaling pathway (GO:0007215)3.05181389
62respiratory chain complex IV assembly (GO:0008535)3.05016040
63long-term synaptic potentiation (GO:0060291)3.04898067
64platelet dense granule organization (GO:0060155)3.03720893
65startle response (GO:0001964)3.03162266
66acidic amino acid transport (GO:0015800)3.02110602
67male meiosis (GO:0007140)3.01962292
68trivalent inorganic cation transport (GO:0072512)3.01754500
69ferric iron transport (GO:0015682)3.01754500
70positive regulation of synapse maturation (GO:0090129)3.00968213
71detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.00618555
72protein polyglutamylation (GO:0018095)3.00530248
73cilium morphogenesis (GO:0060271)3.00287589
74protein localization to cilium (GO:0061512)2.98711392
75regulation of short-term neuronal synaptic plasticity (GO:0048172)2.94489329
76negative regulation of transcription regulatory region DNA binding (GO:2000678)2.93782043
77negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.93138071
78positive regulation of meiosis (GO:0045836)2.91830306
79response to redox state (GO:0051775)2.89842675
80regulation of mitochondrial translation (GO:0070129)2.89482956
81ionotropic glutamate receptor signaling pathway (GO:0035235)2.87445794
82long-chain fatty acid biosynthetic process (GO:0042759)2.86403338
83cilium movement (GO:0003341)2.86061601
84fatty acid elongation (GO:0030497)2.85688335
85gamma-aminobutyric acid signaling pathway (GO:0007214)2.84362732
86resolution of meiotic recombination intermediates (GO:0000712)2.83526823
87glycerophospholipid catabolic process (GO:0046475)2.83284770
88regulation of cilium movement (GO:0003352)2.83209429
89L-glutamate transport (GO:0015813)2.82607747
90protein localization to synapse (GO:0035418)2.81337219
91L-methionine salvage (GO:0071267)2.80841615
92L-methionine biosynthetic process (GO:0071265)2.80841615
93amino acid salvage (GO:0043102)2.80841615
94G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.80024993
95positive regulation of meiotic cell cycle (GO:0051446)2.79475618
96axoneme assembly (GO:0035082)2.78281809
97postsynaptic membrane organization (GO:0001941)2.77604228
98gamma-aminobutyric acid transport (GO:0015812)2.77288519
99steroid catabolic process (GO:0006706)2.76685079
100response to pheromone (GO:0019236)2.75646598
101serine family amino acid biosynthetic process (GO:0009070)2.74039014
102cellular response to leptin stimulus (GO:0044320)2.72762999
103positive regulation of mitochondrial fission (GO:0090141)2.72469993
104behavioral response to cocaine (GO:0048148)2.72031835
105water-soluble vitamin biosynthetic process (GO:0042364)2.71788391
106positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.71744821
107glycine metabolic process (GO:0006544)2.71126401
108cytochrome complex assembly (GO:0017004)2.67285181
109regulation of acyl-CoA biosynthetic process (GO:0050812)2.65367139
110chaperone-mediated protein transport (GO:0072321)2.65275454
111NAD metabolic process (GO:0019674)2.64175134
112response to leptin (GO:0044321)2.62219074
113response to histamine (GO:0034776)2.58860620
114righting reflex (GO:0060013)2.58295429
115negative regulation of cytosolic calcium ion concentration (GO:0051481)2.58100183
116L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.54789124
117aromatic amino acid family catabolic process (GO:0009074)2.54260636
118protein neddylation (GO:0045116)2.53540346
119alanine transport (GO:0032328)2.53215405
120somite development (GO:0061053)2.52977175
121long term synaptic depression (GO:0060292)2.52874585
122positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.52114644
123cilium organization (GO:0044782)2.52112325
124meiosis I (GO:0007127)2.51065466
125response to misfolded protein (GO:0051788)2.49724108
126acrosome assembly (GO:0001675)2.49384706
127pyrimidine dimer repair (GO:0006290)2.49381332
128anterograde synaptic vesicle transport (GO:0048490)2.48383175
129neuron fate determination (GO:0048664)2.48295484
130neurotransmitter secretion (GO:0007269)2.48270044
131protein deneddylation (GO:0000338)2.48242953
132vitamin transmembrane transport (GO:0035461)2.47826102
133triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.47078423
134positive regulation of gastrulation (GO:2000543)2.46578523
135serine family amino acid metabolic process (GO:0009069)2.46499411
136histone H2A acetylation (GO:0043968)2.46369660
137regulation of cofactor metabolic process (GO:0051193)2.45886769
138regulation of coenzyme metabolic process (GO:0051196)2.45886769
139cilium assembly (GO:0042384)2.45369757
140heme transport (GO:0015886)2.45144809
141cullin deneddylation (GO:0010388)2.44952572
142regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.43830533
143nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.43398523
144regulation of synapse maturation (GO:0090128)2.43305469
145sulfur amino acid biosynthetic process (GO:0000097)2.43214461
146quinone biosynthetic process (GO:1901663)2.42453028
147anterograde axon cargo transport (GO:0008089)2.42038601
148regulation of neurotransmitter uptake (GO:0051580)2.41756639
149detection of light stimulus involved in visual perception (GO:0050908)2.40631723
150detection of light stimulus involved in sensory perception (GO:0050962)2.40631723
151ether lipid metabolic process (GO:0046485)2.40374883
152nucleobase catabolic process (GO:0046113)2.39702732
153auditory behavior (GO:0031223)2.38954741
154L-fucose catabolic process (GO:0042355)2.37804340
155fucose catabolic process (GO:0019317)2.37804340
156L-fucose metabolic process (GO:0042354)2.37804340
157pyrimidine nucleobase catabolic process (GO:0006208)2.37317576
158regulation of mitotic spindle checkpoint (GO:1903504)2.37235222
159regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.37235222
160protein-cofactor linkage (GO:0018065)2.36731906
161cellular ketone body metabolic process (GO:0046950)2.36124005
162inner ear receptor stereocilium organization (GO:0060122)2.35570287
163protein K11-linked deubiquitination (GO:0035871)2.35286123
164exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.34865925
165regulation of male gonad development (GO:2000018)2.34633981
166establishment of protein localization to mitochondrial membrane (GO:0090151)2.34332299
167regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.30949351
168regulation of hexokinase activity (GO:1903299)2.29654205
169regulation of glucokinase activity (GO:0033131)2.29654205
170GPI anchor metabolic process (GO:0006505)2.29127143
171RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.28120824
172tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.28120824
173preassembly of GPI anchor in ER membrane (GO:0016254)2.26099340
174smoothened signaling pathway (GO:0007224)2.25607690
175retinal ganglion cell axon guidance (GO:0031290)2.24389104
176photoreceptor cell maintenance (GO:0045494)2.23460184
177reflex (GO:0060004)2.22195104
178mannosylation (GO:0097502)2.20592452
179auditory receptor cell stereocilium organization (GO:0060088)2.20402604
180transmission of nerve impulse (GO:0019226)2.20202918
181negative regulation of telomere maintenance (GO:0032205)2.19858060
182DNA double-strand break processing (GO:0000729)2.18659805
183parturition (GO:0007567)2.18257637

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.20188771
2GBX2_23144817_ChIP-Seq_PC3_Human3.86215874
3EZH2_22144423_ChIP-Seq_EOC_Human3.69060052
4ZNF274_21170338_ChIP-Seq_K562_Hela3.58218287
5PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.68821580
6VDR_22108803_ChIP-Seq_LS180_Human2.49104382
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.46624759
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.41797048
9TAF15_26573619_Chip-Seq_HEK293_Human2.40607301
10IGF1R_20145208_ChIP-Seq_DFB_Human2.39315513
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.37331673
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.34756304
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.34616168
14REST_21632747_ChIP-Seq_MESCs_Mouse2.17228715
15ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.15791833
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.15209596
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.11039048
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.08686616
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06241548
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.97802528
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.92663262
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.92501082
23ZFP57_27257070_Chip-Seq_ESCs_Mouse1.90060706
24EWS_26573619_Chip-Seq_HEK293_Human1.89498083
25SALL1_21062744_ChIP-ChIP_HESCs_Human1.85770182
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.81373003
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.77461832
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.77004142
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.75210218
30FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.74675442
31SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74126319
32BMI1_23680149_ChIP-Seq_NPCS_Mouse1.71652770
33FUS_26573619_Chip-Seq_HEK293_Human1.70169634
34SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.68184720
35REST_18959480_ChIP-ChIP_MESCs_Mouse1.67662233
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.65058873
37EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.63468654
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60073175
39EST1_17652178_ChIP-ChIP_JURKAT_Human1.59391002
40CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.56493879
41RNF2_27304074_Chip-Seq_NSC_Mouse1.55500357
42CREB1_15753290_ChIP-ChIP_HEK293T_Human1.54917970
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.54812659
44CBP_20019798_ChIP-Seq_JUKART_Human1.52217552
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52217552
46TP53_22573176_ChIP-Seq_HFKS_Human1.52162326
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.51628309
48THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49190163
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.48196737
50JARID2_20064375_ChIP-Seq_MESCs_Mouse1.47599467
51RXR_22158963_ChIP-Seq_LIVER_Mouse1.44835752
52SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44402107
53HTT_18923047_ChIP-ChIP_STHdh_Human1.43818473
54EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.40787017
55AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.40357866
56SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.39972021
57SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.39472353
58CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.37118028
59GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36469710
60ETS1_20019798_ChIP-Seq_JURKAT_Human1.36254293
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34607412
62SMAD4_21799915_ChIP-Seq_A2780_Human1.34507860
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31740408
64HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.31508988
65EGR1_23403033_ChIP-Seq_LIVER_Mouse1.30992231
66MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.30517239
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30141307
68P300_19829295_ChIP-Seq_ESCs_Human1.29743292
69EZH2_27304074_Chip-Seq_ESCs_Mouse1.29357553
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.28842557
71SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28176075
72PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27586732
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27314682
74ELK1_19687146_ChIP-ChIP_HELA_Human1.25840629
75TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25506193
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.25506193
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25080701
78SMAD3_21741376_ChIP-Seq_EPCs_Human1.23434993
79BCAT_22108803_ChIP-Seq_LS180_Human1.22729025
80SOX2_19829295_ChIP-Seq_ESCs_Human1.22699437
81NANOG_19829295_ChIP-Seq_ESCs_Human1.22699437
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22544253
83KAP1_22055183_ChIP-Seq_ESCs_Mouse1.20766844
84POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20389263
85MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20331309
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.19573899
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.19234386
88CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.18521840
89BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.18327304
90TCF4_22108803_ChIP-Seq_LS180_Human1.16962898
91NFE2_27457419_Chip-Seq_LIVER_Mouse1.15900228
92MYC_18940864_ChIP-ChIP_HL60_Human1.15868741
93IRF1_19129219_ChIP-ChIP_H3396_Human1.14953212
94SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.14453000
95AUTS2_25519132_ChIP-Seq_293T-REX_Human1.14434145
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.13457433
97LXR_22158963_ChIP-Seq_LIVER_Mouse1.13069841
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11172201
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.10424112
100SMAD4_21741376_ChIP-Seq_EPCs_Human1.07579546
101CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06472847
102RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05958869
103FOXA1_25329375_ChIP-Seq_VCAP_Human1.05044463
104FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05044463
105EZH2_18974828_ChIP-Seq_MESCs_Mouse1.04222766
106RNF2_18974828_ChIP-Seq_MESCs_Mouse1.04222766
107JARID2_20075857_ChIP-Seq_MESCs_Mouse1.04132735
108TCF4_23295773_ChIP-Seq_U87_Human1.04108536
109VDR_23849224_ChIP-Seq_CD4+_Human1.02184232
110NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.02014563
111AR_21572438_ChIP-Seq_LNCaP_Human1.02002614
112SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.01409995
113EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99618897
114EED_16625203_ChIP-ChIP_MESCs_Mouse0.98571951
115FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98484201
116TAL1_26923725_Chip-Seq_HPCs_Mouse0.98025063
117NCOR_22424771_ChIP-Seq_293T_Human0.97687019
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97101142
119AR_20517297_ChIP-Seq_VCAP_Human0.96891270
120CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95954718
121POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95296431
122JUN_21703547_ChIP-Seq_K562_Human0.94940685
123HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94325419
124LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93874604
125P53_22387025_ChIP-Seq_ESCs_Mouse0.93628106
126TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.93332157
127YY1_21170310_ChIP-Seq_MESCs_Mouse0.92926969
128CRX_20693478_ChIP-Seq_RETINA_Mouse0.92922065
129SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91478014
130CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90955774
131SOX2_21211035_ChIP-Seq_LN229_Gbm0.90913149
132P53_22127205_ChIP-Seq_FIBROBLAST_Human0.90678087
133AR_25329375_ChIP-Seq_VCAP_Human0.90645527
134UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90014666
135PPARA_22158963_ChIP-Seq_LIVER_Mouse0.89966008
136EZH2_27294783_Chip-Seq_ESCs_Mouse0.89709981
137OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89505692
138SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.88188873
139STAT3_23295773_ChIP-Seq_U87_Human0.88151945
140NOTCH1_21737748_ChIP-Seq_TLL_Human0.87768191
141RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.87597441
142DROSHA_22980978_ChIP-Seq_HELA_Human0.86584209
143SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.86136673
144TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.85976318
145SOX9_26525672_Chip-Seq_HEART_Mouse0.85415859
146SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85193682
147RNF2_27304074_Chip-Seq_ESCs_Mouse0.84867664
148PIAS1_25552417_ChIP-Seq_VCAP_Human0.84434961
149PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.84236782
150NANOG_18555785_Chip-Seq_ESCs_Mouse0.83170838
151ER_23166858_ChIP-Seq_MCF-7_Human0.83036162
152RUNX2_22187159_ChIP-Seq_PCA_Human0.82192998
153GABP_17652178_ChIP-ChIP_JURKAT_Human0.82122705
154TET1_21490601_ChIP-Seq_MESCs_Mouse0.79851337
155SUZ12_27294783_Chip-Seq_ESCs_Mouse0.79138616
156FOXH1_21741376_ChIP-Seq_EPCs_Human0.78428576

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.12879879
2MP0002139_abnormal_hepatobiliary_system3.40003190
3MP0004859_abnormal_synaptic_plasticity3.00623743
4MP0000013_abnormal_adipose_tissue2.69218793
5MP0003635_abnormal_synaptic_transmissio2.55019182
6MP0001486_abnormal_startle_reflex2.49277692
7MP0009745_abnormal_behavioral_response2.46585399
8MP0004885_abnormal_endolymph2.46061231
9MP0002064_seizures2.42644995
10MP0009046_muscle_twitch2.25007817
11MP0001501_abnormal_sleep_pattern2.21903016
12MP0005646_abnormal_pituitary_gland2.20784676
13MP0002837_dystrophic_cardiac_calcinosis2.20417699
14MP0002272_abnormal_nervous_system2.18527518
15MP0008875_abnormal_xenobiotic_pharmacok2.14786745
16MP0002063_abnormal_learning/memory/cond2.12193002
17MP0003329_amyloid_beta_deposits2.10766769
18MP0005085_abnormal_gallbladder_physiolo2.09878261
19MP0008877_abnormal_DNA_methylation2.03787811
20MP0005365_abnormal_bile_salt1.98811026
21MP0003879_abnormal_hair_cell1.95623052
22MP0002572_abnormal_emotion/affect_behav1.95594598
23MP0008789_abnormal_olfactory_epithelium1.92563690
24MP0005360_urolithiasis1.91297091
25MP0003122_maternal_imprinting1.89193233
26MP0003646_muscle_fatigue1.83223084
27MP0003718_maternal_effect1.81665782
28MP0001485_abnormal_pinna_reflex1.79923372
29MP0003806_abnormal_nucleotide_metabolis1.79842339
30MP0001968_abnormal_touch/_nociception1.74905923
31MP0002638_abnormal_pupillary_reflex1.70680470
32MP0002102_abnormal_ear_morphology1.66564470
33MP0006072_abnormal_retinal_apoptosis1.65008909
34MP0002938_white_spotting1.61548576
35MP0005645_abnormal_hypothalamus_physiol1.59568356
36MP0001502_abnormal_circadian_rhythm1.56716031
37MP0005253_abnormal_eye_physiology1.55254127
38MP0000631_abnormal_neuroendocrine_gland1.54170525
39MP0004270_analgesia1.51690709
40MP0002234_abnormal_pharynx_morphology1.50817686
41MP0003011_delayed_dark_adaptation1.49681905
42MP0001905_abnormal_dopamine_level1.47824205
43MP0002822_catalepsy1.47800589
44MP0009840_abnormal_foam_cell1.47380498
45MP0001529_abnormal_vocalization1.46410019
46MP0004142_abnormal_muscle_tone1.45975738
47MP0002876_abnormal_thyroid_physiology1.44751662
48MP0004215_abnormal_myocardial_fiber1.42587302
49MP0005394_taste/olfaction_phenotype1.40823730
50MP0005499_abnormal_olfactory_system1.40823730
51MP0005451_abnormal_body_composition1.40649119
52MP0002736_abnormal_nociception_after1.40389922
53MP0004036_abnormal_muscle_relaxation1.40318812
54MP0001764_abnormal_homeostasis1.39200291
55MP0006276_abnormal_autonomic_nervous1.37944242
56MP0003690_abnormal_glial_cell1.37471027
57MP0008995_early_reproductive_senescence1.34065791
58MP0006292_abnormal_olfactory_placode1.30984288
59MP0009780_abnormal_chondrocyte_physiolo1.29135864
60MP0005332_abnormal_amino_acid1.28520690
61MP0000049_abnormal_middle_ear1.28419452
62MP0001440_abnormal_grooming_behavior1.27257188
63MP0000569_abnormal_digit_pigmentation1.26212306
64MP0003121_genomic_imprinting1.25261455
65MP0005377_hearing/vestibular/ear_phenot1.25166649
66MP0003878_abnormal_ear_physiology1.25166649
67MP0002067_abnormal_sensory_capabilities1.24694116
68MP0005187_abnormal_penis_morphology1.23798677
69MP0006036_abnormal_mitochondrial_physio1.23341445
70MP0001661_extended_life_span1.22137455
71MP0004043_abnormal_pH_regulation1.20140771
72MP0010030_abnormal_orbit_morphology1.18697107
73MP0003937_abnormal_limbs/digits/tail_de1.18599811
74MP0000778_abnormal_nervous_system1.18210396
75MP0004084_abnormal_cardiac_muscle1.17140102
76MP0001963_abnormal_hearing_physiology1.15911885
77MP0002751_abnormal_autonomic_nervous1.15801486
78MP0002210_abnormal_sex_determination1.14823051
79MP0004133_heterotaxia1.13691276
80MP0002557_abnormal_social/conspecific_i1.13108885
81MP0001984_abnormal_olfaction1.08154879
82MP0008058_abnormal_DNA_repair1.08112324
83MP0000604_amyloidosis1.04167871
84MP0004924_abnormal_behavior1.04121236
85MP0005386_behavior/neurological_phenoty1.04121236
86MP0004147_increased_porphyrin_level1.04041095
87MP0002066_abnormal_motor_capabilities/c1.02915124
88MP0000427_abnormal_hair_cycle1.02484151
89MP0005423_abnormal_somatic_nervous1.02232212
90MP0001929_abnormal_gametogenesis1.02188735
91MP0001986_abnormal_taste_sensitivity1.01441336
92MP0002229_neurodegeneration1.01376156
93MP0005084_abnormal_gallbladder_morpholo1.00141287
94MP0002909_abnormal_adrenal_gland0.98935489
95MP0005551_abnormal_eye_electrophysiolog0.98338203
96MP0002734_abnormal_mechanical_nocicepti0.97587137
97MP0003755_abnormal_palate_morphology0.96988607
98MP0005670_abnormal_white_adipose0.96785630
99MP0000653_abnormal_sex_gland0.96724098
100MP0002163_abnormal_gland_morphology0.95176539
101MP0008872_abnormal_physiological_respon0.94601814
102MP0008569_lethality_at_weaning0.93774163
103MP0008057_abnormal_DNA_replication0.93627147
104MP0002184_abnormal_innervation0.92490834
105MP0003786_premature_aging0.91247352
106MP0010329_abnormal_lipoprotein_level0.91090124
107MP0000003_abnormal_adipose_tissue0.91085032
108MP0010386_abnormal_urinary_bladder0.90558158
109MP0000647_abnormal_sebaceous_gland0.90457375
110MP0002233_abnormal_nose_morphology0.90452121
111MP0002108_abnormal_muscle_morphology0.89806251
112MP0003787_abnormal_imprinting0.89592532
113MP0002752_abnormal_somatic_nervous0.88772409
114MP0002735_abnormal_chemical_nociception0.88634313
115MP0004085_abnormal_heartbeat0.88580348
116MP0001293_anophthalmia0.88219765
117MP0004233_abnormal_muscle_weight0.87005608
118MP0002160_abnormal_reproductive_system0.86487648
119MP0001145_abnormal_male_reproductive0.85878583
120MP0000751_myopathy0.85648384
121MP0002118_abnormal_lipid_homeostasis0.85247877
122MP0005379_endocrine/exocrine_gland_phen0.84515223
123MP0000026_abnormal_inner_ear0.84334516
124MP0003890_abnormal_embryonic-extraembry0.83780750
125MP0000750_abnormal_muscle_regeneration0.83465525
126MP0001970_abnormal_pain_threshold0.83115394
127MP0003868_abnormal_feces_composition0.82681672
128MP0002095_abnormal_skin_pigmentation0.81470586
129MP0005195_abnormal_posterior_eye0.80845760
130MP0004145_abnormal_muscle_electrophysio0.80017325
131MP0003136_yellow_coat_color0.78925939
132MP0000230_abnormal_systemic_arterial0.78106284
133MP0003195_calcinosis0.77490412
134MP0000749_muscle_degeneration0.76761666
135MP0003631_nervous_system_phenotype0.76078687
136MP0002653_abnormal_ependyma_morphology0.75767119
137MP0000639_abnormal_adrenal_gland0.74295381
138MP0009697_abnormal_copulation0.73510903
139MP0005535_abnormal_body_temperature0.73387191
140MP0003632_abnormal_nervous_system0.73383083
141MP0000955_abnormal_spinal_cord0.72176859
142MP0006138_congestive_heart_failure0.71944936
143MP0003698_abnormal_male_reproductive0.71829290
144MP0003137_abnormal_impulse_conducting0.71221809
145MP0002127_abnormal_cardiovascular_syste0.70802358
146MP0005330_cardiomyopathy0.70193525
147MP0002882_abnormal_neuron_morphology0.70159568
148MP0002269_muscular_atrophy0.69959685
149MP0003633_abnormal_nervous_system0.69935739

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.85617619
2Acute necrotizing encephalopathy (HP:0006965)4.42361814
3Hyperventilation (HP:0002883)4.40967290
4Acute encephalopathy (HP:0006846)4.00438429
5Pancreatic cysts (HP:0001737)3.97493473
6Abnormal mitochondria in muscle tissue (HP:0008316)3.97216976
7True hermaphroditism (HP:0010459)3.86706485
8Molar tooth sign on MRI (HP:0002419)3.84217693
9Abnormality of midbrain morphology (HP:0002418)3.84217693
10Gout (HP:0001997)3.82328173
11Pancreatic fibrosis (HP:0100732)3.81110052
12Mitochondrial inheritance (HP:0001427)3.61588420
13Increased CSF lactate (HP:0002490)3.54422442
14Progressive macrocephaly (HP:0004481)3.51154409
15Type II lissencephaly (HP:0007260)3.50750469
16Cerebral edema (HP:0002181)3.49347217
17Increased serum pyruvate (HP:0003542)3.48824256
18Abnormality of glycolysis (HP:0004366)3.48824256
19Atonic seizures (HP:0010819)3.46390278
20Nephronophthisis (HP:0000090)3.37497826
21Epileptic encephalopathy (HP:0200134)3.19313617
22Hepatocellular necrosis (HP:0001404)3.17282923
23Abnormality of the labia minora (HP:0012880)3.16040825
24Hyperglycinemia (HP:0002154)3.15859948
25Cerebral hypomyelination (HP:0006808)3.04878888
26Cerebellar dysplasia (HP:0007033)3.04418361
27Hyperglycinuria (HP:0003108)2.93266517
28Abnormality of the renal medulla (HP:0100957)2.85526348
29Abnormality of serine family amino acid metabolism (HP:0010894)2.83863676
30Abnormality of glycine metabolism (HP:0010895)2.83863676
31Cholecystitis (HP:0001082)2.82012790
32Abnormal gallbladder physiology (HP:0012438)2.82012790
33Focal seizures (HP:0007359)2.81090670
34Abnormality of aromatic amino acid family metabolism (HP:0004338)2.78511197
35Retinal dysplasia (HP:0007973)2.74087475
36Hepatic necrosis (HP:0002605)2.69152364
37Oligodactyly (hands) (HP:0001180)2.67354289
38Lethargy (HP:0001254)2.63076334
39Abnormality of the axillary hair (HP:0100134)2.59062962
40Abnormality of secondary sexual hair (HP:0009888)2.59062962
41Epileptiform EEG discharges (HP:0011182)2.54918629
42Abnormality of the renal cortex (HP:0011035)2.54719671
43Aplasia/Hypoplasia of the tongue (HP:0010295)2.51963327
44Cystic liver disease (HP:0006706)2.49159373
45Congenital stationary night blindness (HP:0007642)2.48434233
46Delusions (HP:0000746)2.47293436
47Leukodystrophy (HP:0002415)2.45938983
48Intestinal atresia (HP:0011100)2.44914137
49Polydipsia (HP:0001959)2.43735017
50Abnormal drinking behavior (HP:0030082)2.43735017
51Septo-optic dysplasia (HP:0100842)2.43484845
52Genital tract atresia (HP:0001827)2.41541599
53EEG with generalized epileptiform discharges (HP:0011198)2.39726180
54CNS demyelination (HP:0007305)2.39480379
55Xanthomatosis (HP:0000991)2.38653118
56Vaginal atresia (HP:0000148)2.37341807
57Optic nerve hypoplasia (HP:0000609)2.36795478
58Sclerocornea (HP:0000647)2.36559047
59Lactic acidosis (HP:0003128)2.34300643
60Congenital malformation of the right heart (HP:0011723)2.33962861
61Double outlet right ventricle (HP:0001719)2.33962861
62Brittle hair (HP:0002299)2.33640558
63Ketosis (HP:0001946)2.32719282
64Anencephaly (HP:0002323)2.32120330
65Colon cancer (HP:0003003)2.31912260
66Respiratory failure (HP:0002878)2.31633040
67Chronic hepatic failure (HP:0100626)2.31095675
68Bile duct proliferation (HP:0001408)2.28680797
69Abnormal biliary tract physiology (HP:0012439)2.28680797
70Unsteady gait (HP:0002317)2.27748677
71Poor eye contact (HP:0000817)2.27599069
72Lissencephaly (HP:0001339)2.27564852
73Prolonged partial thromboplastin time (HP:0003645)2.26461030
74Hypsarrhythmia (HP:0002521)2.26384885
75Sensory axonal neuropathy (HP:0003390)2.26028369
76Dialeptic seizures (HP:0011146)2.25881245
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.24171754
78Emotional lability (HP:0000712)2.22689634
79Optic disc pallor (HP:0000543)2.22382208
80Large for gestational age (HP:0001520)2.20893328
81Poor coordination (HP:0002370)2.20868582
82Abnormality of serum amino acid levels (HP:0003112)2.20483896
83Occipital encephalocele (HP:0002085)2.18324320
84Absence seizures (HP:0002121)2.17595071
85Myokymia (HP:0002411)2.16783485
86Generalized tonic-clonic seizures (HP:0002069)2.16141351
87Gait imbalance (HP:0002141)2.15922689
88Fused cervical vertebrae (HP:0002949)2.13654411
89Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.13584909
90Abnormality of methionine metabolism (HP:0010901)2.12549964
91Febrile seizures (HP:0002373)2.11963388
92Supernumerary spleens (HP:0009799)2.10870835
93Congenital primary aphakia (HP:0007707)2.09289269
94Male pseudohermaphroditism (HP:0000037)2.08604963
95Postaxial hand polydactyly (HP:0001162)2.08279272
963-Methylglutaconic aciduria (HP:0003535)2.06581345
97Tubular atrophy (HP:0000092)2.06206569
98Intrahepatic cholestasis (HP:0001406)2.06016142
99Hyperglycemia (HP:0003074)2.05010654
100Broad-based gait (HP:0002136)2.04448002
101Hypobetalipoproteinemia (HP:0003563)2.04244460
102Increased serum lactate (HP:0002151)2.03545805
103Aplasia/hypoplasia of the uterus (HP:0008684)2.03294902
104Abnormal social behavior (HP:0012433)2.02719821
105Impaired social interactions (HP:0000735)2.02719821
106Deep venous thrombosis (HP:0002625)2.02507610
107Degeneration of the lateral corticospinal tracts (HP:0002314)2.02261182
108Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.02261182
109Anomalous pulmonary venous return (HP:0010772)2.01697559
110Confusion (HP:0001289)2.01299785
111Increased purine levels (HP:0004368)2.01177321
112Hyperuricemia (HP:0002149)2.01177321
113Congenital hepatic fibrosis (HP:0002612)2.00789550
114Abolished electroretinogram (ERG) (HP:0000550)1.99678404
115Postaxial foot polydactyly (HP:0001830)1.95488685
116Polyuria (HP:0000103)1.93731546
117Increased hepatocellular lipid droplets (HP:0006565)1.93379004
118Acute hepatic failure (HP:0006554)1.92258332
119Preaxial hand polydactyly (HP:0001177)1.89892563
120Hyperinsulinemic hypoglycemia (HP:0000825)1.87608574
121Nephrogenic diabetes insipidus (HP:0009806)1.86942383
122Attenuation of retinal blood vessels (HP:0007843)1.86622171
123Medial flaring of the eyebrow (HP:0010747)1.85475654
124Absent speech (HP:0001344)1.85355236
125Median cleft lip (HP:0000161)1.85293764
126Impaired vibration sensation in the lower limbs (HP:0002166)1.85258316
127Pendular nystagmus (HP:0012043)1.84616502
128Exercise intolerance (HP:0003546)1.82704945
129Irregular epiphyses (HP:0010582)1.80827115
130Atrioventricular block (HP:0001678)1.80323617
131Muscle hypertrophy of the lower extremities (HP:0008968)1.79564391
132Hypomagnesemia (HP:0002917)1.79464331
133Visual hallucinations (HP:0002367)1.78682375
134Concave nail (HP:0001598)1.77780418
135Urinary bladder sphincter dysfunction (HP:0002839)1.77562703
136Renal cortical cysts (HP:0000803)1.76790768
137Absent septum pellucidum (HP:0001331)1.75604230
138Abnormality of aspartate family amino acid metabolism (HP:0010899)1.75456258
139Abnormality of abdominal situs (HP:0011620)1.75421829
140Abdominal situs inversus (HP:0003363)1.75421829
141Lipid accumulation in hepatocytes (HP:0006561)1.75318018
142Abnormality of the corticospinal tract (HP:0002492)1.74914368
143Gaze-evoked nystagmus (HP:0000640)1.74412927
144Abnormality of the lower motor neuron (HP:0002366)1.74184559
145Exercise-induced muscle cramps (HP:0003710)1.72716779
146X-linked dominant inheritance (HP:0001423)1.71854794
147Pachygyria (HP:0001302)1.71640611
148Insulin-resistant diabetes mellitus (HP:0000831)1.71375755
149Hypothermia (HP:0002045)1.70865767
150Abnormality of renal resorption (HP:0011038)1.70482499
151Renal Fanconi syndrome (HP:0001994)1.69868675
152Birth length less than 3rd percentile (HP:0003561)1.69679118
153Status epilepticus (HP:0002133)1.69324138
154Narrow forehead (HP:0000341)1.69237694
155Abnormal respiratory motile cilium physiology (HP:0012261)1.69225675
156Methylmalonic aciduria (HP:0012120)1.69219642
157Severe muscular hypotonia (HP:0006829)1.67154504
158Hypolipoproteinemia (HP:0010981)1.66915032
159Methylmalonic acidemia (HP:0002912)1.66824897
160Abnormal hair whorl (HP:0010721)1.65778620
161Ketoacidosis (HP:0001993)1.65361144
162Aplasia/Hypoplasia of the tibia (HP:0005772)1.65182137
163Tubulointerstitial nephritis (HP:0001970)1.64284748
164Decreased electroretinogram (ERG) amplitude (HP:0000654)1.62684583
165Left ventricular hypertrophy (HP:0001712)1.62114558
166Rhinitis (HP:0012384)1.61881408
167Bifid tongue (HP:0010297)1.61712679
168Aganglionic megacolon (HP:0002251)1.60867266
169Retinal atrophy (HP:0001105)1.60373813
170Specific learning disability (HP:0001328)1.58749411

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.79571796
2MUSK3.80575374
3EPHA43.48680555
4FRK3.22861048
5AKT33.07467950
6MAP4K22.77394007
7WNK32.73077270
8MAP3K42.63769865
9RIPK12.56599245
10TSSK62.53345817
11NTRK32.35712580
12CCNB12.34249668
13BUB12.32265684
14BMPR1B2.06389783
15PDK42.03516798
16PDK32.03516798
17OXSR11.86233638
18PLK21.85081291
19TRIM281.80751077
20ZAK1.80346486
21NUAK11.80041358
22PDK21.76354313
23LATS21.60843912
24MAP3K91.58094081
25MAP2K71.52098742
26WNK41.50743710
27CSNK1G11.43582732
28TNIK1.42103406
29PAK31.40635898
30ADRBK21.35836892
31WEE11.31720078
32LATS11.31647930
33DAPK21.31108168
34PRKCG1.29264646
35NME11.28671795
36CSNK1G31.27891145
37CDK191.26824212
38DYRK21.26724603
39PLK31.25937359
40MAP2K41.17820224
41ACVR1B1.16967734
42PNCK1.15966336
43BCKDK1.14834768
44PAK61.07526628
45PKN11.07268091
46BMPR21.07048885
47MAPK71.02893157
48STK38L1.02271084
49TIE11.00806756
50STK390.99619906
51NEK60.97731003
52PTK2B0.96826989
53VRK10.95804046
54INSRR0.95575644
55ERBB40.94181720
56SRPK10.92811319
57PINK10.92017346
58BRSK10.90888472
59CAMK2A0.90821687
60CSNK1A1L0.88433083
61PRPF4B0.88379806
62MARK30.88177595
63BRSK20.87860436
64RIPK40.86126996
65ARAF0.85601193
66PBK0.85166543
67ERBB30.85102637
68DAPK10.80632142
69MKNK10.77002681
70TAOK30.76256888
71CDK50.72657624
72EPHB20.72237789
73ADRBK10.72092000
74CAMK2B0.72008102
75PRKCH0.71367470
76TTK0.71127876
77STK160.70081154
78NLK0.69971804
79PDPK10.69859849
80NTRK20.69438595
81BRAF0.68867360
82CSNK1E0.67660444
83OBSCN0.66972187
84NEK10.65508747
85STK30.63694026
86MAPK120.63603595
87LIMK10.63458751
88DYRK30.62955253
89TLK10.62700279
90PRKCI0.60940935
91MAPK130.60690710
92DYRK1A0.58182512
93FGFR20.58001767
94MKNK20.57390639
95PHKG10.57286081
96PHKG20.57286081
97TGFBR10.56888628
98VRK20.55717578
99GRK50.53797598
100SGK4940.53681681
101SGK2230.53681681
102NTRK10.53065560
103KSR10.51754629
104PLK40.51079583
105PDK10.50436206
106PRKACA0.50239916
107CAMK2D0.50236602
108FES0.49813336
109EIF2AK30.49385584
110CAMK10.49189696
111CDK150.48999466
112PIK3CA0.48466935
113PRKG10.48459187
114GRK10.48421963
115CDK180.48344278
116PRKCE0.47052826
117PLK10.46598070
118CSNK1A10.45920145
119STK110.45283935
120PRKACB0.45186605
121MAP3K130.44815058
122BCR0.43936511
123UHMK10.43667450
124PRKD30.43570315
125CAMK1G0.43370589
126CSNK1D0.43344324
127MST40.42960952
128CDK11A0.41811152
129CDK30.41762420
130GRK70.40997294
131PRKAA10.40829365
132MELK0.40642468
133RPS6KA30.40468652
134EPHA20.40035939
135MARK10.38910289
136STK380.38703218
137CSNK1G20.38552521
138MAPK150.37896858
139CHEK10.37798128
140CAMK2G0.36609021
141TAOK10.35706182
142PRKCA0.35353402
143CDK140.34620567

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.77487796
2Vitamin B6 metabolism_Homo sapiens_hsa007503.30247689
3Oxidative phosphorylation_Homo sapiens_hsa001903.08958672
4Protein export_Homo sapiens_hsa030602.86821132
5Collecting duct acid secretion_Homo sapiens_hsa049662.59121608
6Synaptic vesicle cycle_Homo sapiens_hsa047212.42209953
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.39629338
8Nicotine addiction_Homo sapiens_hsa050332.36508243
9Phototransduction_Homo sapiens_hsa047442.23024653
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.07644468
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.04705684
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.01905600
13Arginine biosynthesis_Homo sapiens_hsa002201.98966224
14Parkinsons disease_Homo sapiens_hsa050121.91535085
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.89398963
16RNA polymerase_Homo sapiens_hsa030201.84040062
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.81577505
18Cysteine and methionine metabolism_Homo sapiens_hsa002701.79242851
19Biosynthesis of amino acids_Homo sapiens_hsa012301.78337331
20Primary bile acid biosynthesis_Homo sapiens_hsa001201.72922492
21Alzheimers disease_Homo sapiens_hsa050101.71972127
22RNA degradation_Homo sapiens_hsa030181.69494652
23Regulation of autophagy_Homo sapiens_hsa041401.67659276
24Linoleic acid metabolism_Homo sapiens_hsa005911.67067186
25Huntingtons disease_Homo sapiens_hsa050161.66153374
26Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.65210863
27Pyruvate metabolism_Homo sapiens_hsa006201.61670299
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.59656356
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.55754302
30Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.53553912
31Cyanoamino acid metabolism_Homo sapiens_hsa004601.50428332
32Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.50259668
33Circadian rhythm_Homo sapiens_hsa047101.49157322
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.48463554
35Butanoate metabolism_Homo sapiens_hsa006501.46461430
36Sulfur metabolism_Homo sapiens_hsa009201.44702153
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.42577329
38Fanconi anemia pathway_Homo sapiens_hsa034601.40328793
39Selenocompound metabolism_Homo sapiens_hsa004501.39495978
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38026758
41Amphetamine addiction_Homo sapiens_hsa050311.36402956
42Fatty acid elongation_Homo sapiens_hsa000621.35987949
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.29726943
44Glutamatergic synapse_Homo sapiens_hsa047241.27958196
45GABAergic synapse_Homo sapiens_hsa047271.25539689
46Vibrio cholerae infection_Homo sapiens_hsa051101.25086746
47Homologous recombination_Homo sapiens_hsa034401.23995007
48Propanoate metabolism_Homo sapiens_hsa006401.22766773
49Cardiac muscle contraction_Homo sapiens_hsa042601.22702815
50Carbon metabolism_Homo sapiens_hsa012001.22664841
51Steroid biosynthesis_Homo sapiens_hsa001001.17374806
52Circadian entrainment_Homo sapiens_hsa047131.14017640
53Ether lipid metabolism_Homo sapiens_hsa005651.12986625
54Insulin secretion_Homo sapiens_hsa049111.10820460
55Phenylalanine metabolism_Homo sapiens_hsa003601.08771400
56Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.06608888
57Long-term potentiation_Homo sapiens_hsa047201.05154756
58Arginine and proline metabolism_Homo sapiens_hsa003301.05100152
59Morphine addiction_Homo sapiens_hsa050321.02945774
60Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.01299357
61Caffeine metabolism_Homo sapiens_hsa002320.97883242
62Proteasome_Homo sapiens_hsa030500.96656501
63Fatty acid metabolism_Homo sapiens_hsa012120.90150846
64One carbon pool by folate_Homo sapiens_hsa006700.89133697
65Taste transduction_Homo sapiens_hsa047420.86896135
66Chemical carcinogenesis_Homo sapiens_hsa052040.85730552
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.84224207
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.83992784
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.83945585
70Peroxisome_Homo sapiens_hsa041460.82304750
71Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.82259199
72Fatty acid degradation_Homo sapiens_hsa000710.81275797
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80544201
74Ribosome_Homo sapiens_hsa030100.77376855
75Dopaminergic synapse_Homo sapiens_hsa047280.77042027
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75198672
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.73748583
78Metabolic pathways_Homo sapiens_hsa011000.71996060
79Aldosterone synthesis and secretion_Homo sapiens_hsa049250.71817667
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71618406
81Glucagon signaling pathway_Homo sapiens_hsa049220.71265060
82Rheumatoid arthritis_Homo sapiens_hsa053230.70975519
83Basal transcription factors_Homo sapiens_hsa030220.69889603
84Mineral absorption_Homo sapiens_hsa049780.69793055
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.68259012
86Hedgehog signaling pathway_Homo sapiens_hsa043400.68120984
87Steroid hormone biosynthesis_Homo sapiens_hsa001400.67353128
88Oocyte meiosis_Homo sapiens_hsa041140.67224156
89Maturity onset diabetes of the young_Homo sapiens_hsa049500.66984885
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.66707871
91Vitamin digestion and absorption_Homo sapiens_hsa049770.65988534
92Salivary secretion_Homo sapiens_hsa049700.64394514
93Nitrogen metabolism_Homo sapiens_hsa009100.63789476
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63729259
95Pyrimidine metabolism_Homo sapiens_hsa002400.63513806
96Base excision repair_Homo sapiens_hsa034100.63236864
97Calcium signaling pathway_Homo sapiens_hsa040200.62409878
98Nucleotide excision repair_Homo sapiens_hsa034200.60311783
99Tyrosine metabolism_Homo sapiens_hsa003500.59964003
100Cocaine addiction_Homo sapiens_hsa050300.59959149
101Pentose phosphate pathway_Homo sapiens_hsa000300.59157395
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58295277
103Folate biosynthesis_Homo sapiens_hsa007900.56984916
104Serotonergic synapse_Homo sapiens_hsa047260.56237683
105Sulfur relay system_Homo sapiens_hsa041220.54709247
106Mismatch repair_Homo sapiens_hsa034300.54651129
107beta-Alanine metabolism_Homo sapiens_hsa004100.54404036
108Long-term depression_Homo sapiens_hsa047300.53837448
109Arachidonic acid metabolism_Homo sapiens_hsa005900.53086227
110Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52357629
111Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52241100
112Dorso-ventral axis formation_Homo sapiens_hsa043200.51992652
113Glutathione metabolism_Homo sapiens_hsa004800.51937753
114Olfactory transduction_Homo sapiens_hsa047400.50753076
115Tryptophan metabolism_Homo sapiens_hsa003800.50620057
116Basal cell carcinoma_Homo sapiens_hsa052170.50232234
117Ovarian steroidogenesis_Homo sapiens_hsa049130.49964217
118Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49443250
119Glycerolipid metabolism_Homo sapiens_hsa005610.48653286
120Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48640840
121Retinol metabolism_Homo sapiens_hsa008300.48581188
122Fructose and mannose metabolism_Homo sapiens_hsa000510.47114728
123PPAR signaling pathway_Homo sapiens_hsa033200.45993860
124Fat digestion and absorption_Homo sapiens_hsa049750.45422569
125Purine metabolism_Homo sapiens_hsa002300.44481492
126Fatty acid biosynthesis_Homo sapiens_hsa000610.44260006
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43529662
128Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43528583
129Histidine metabolism_Homo sapiens_hsa003400.41345006
130Cholinergic synapse_Homo sapiens_hsa047250.40730744
131Non-homologous end-joining_Homo sapiens_hsa034500.40076669
132RNA transport_Homo sapiens_hsa030130.38177794
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38116365
134Complement and coagulation cascades_Homo sapiens_hsa046100.37182854
135Drug metabolism - other enzymes_Homo sapiens_hsa009830.36868615
136Bile secretion_Homo sapiens_hsa049760.36804586
137ABC transporters_Homo sapiens_hsa020100.34754587
138Oxytocin signaling pathway_Homo sapiens_hsa049210.34660129

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