CHCHD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.30616831
2mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.81114387
3protein complex biogenesis (GO:0070271)5.52002431
4viral transcription (GO:0019083)5.45298499
5ribosomal small subunit biogenesis (GO:0042274)5.42546666
6respiratory electron transport chain (GO:0022904)5.41578362
7electron transport chain (GO:0022900)5.35901080
8translational termination (GO:0006415)5.31556348
9maturation of SSU-rRNA (GO:0030490)5.28665828
10proteasome assembly (GO:0043248)5.17070818
11mitochondrial respiratory chain complex assembly (GO:0033108)5.14147258
12mitochondrial respiratory chain complex I assembly (GO:0032981)4.98749584
13NADH dehydrogenase complex assembly (GO:0010257)4.98749584
14mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.98749584
15ribosomal large subunit biogenesis (GO:0042273)4.93959547
16chaperone-mediated protein transport (GO:0072321)4.84566079
17respiratory chain complex IV assembly (GO:0008535)4.73391777
18SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.73185646
19translational elongation (GO:0006414)4.68951284
20cotranslational protein targeting to membrane (GO:0006613)4.67882953
21protein targeting to ER (GO:0045047)4.62240208
22DNA deamination (GO:0045006)4.59884886
23cytochrome complex assembly (GO:0017004)4.55488401
24translational initiation (GO:0006413)4.47298345
25protein localization to endoplasmic reticulum (GO:0070972)4.40837247
26protein neddylation (GO:0045116)4.40828333
27establishment of protein localization to endoplasmic reticulum (GO:0072599)4.36371925
28negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.32457444
29formation of translation preinitiation complex (GO:0001731)4.30181640
30ribonucleoprotein complex biogenesis (GO:0022613)4.24375444
31positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.16306262
32viral life cycle (GO:0019058)4.16131084
33cellular protein complex disassembly (GO:0043624)4.16003052
34termination of RNA polymerase III transcription (GO:0006386)4.15361135
35transcription elongation from RNA polymerase III promoter (GO:0006385)4.15361135
36translation (GO:0006412)4.14760410
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.10955274
38purine nucleobase biosynthetic process (GO:0009113)4.06234492
39regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.05889994
40termination of RNA polymerase I transcription (GO:0006363)4.05130524
41transcription elongation from RNA polymerase I promoter (GO:0006362)4.05116351
42nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.02645114
43anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.01552221
44cullin deneddylation (GO:0010388)3.99331542
45negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.97044661
46negative regulation of ligase activity (GO:0051352)3.97044661
47nucleobase biosynthetic process (GO:0046112)3.97024927
48DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.94692479
49regulation of cellular amino acid metabolic process (GO:0006521)3.88351893
50signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.86568934
51intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.86568934
52signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.86109150
53signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.86109150
54signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.86109150
55rRNA processing (GO:0006364)3.82741084
56tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.81856299
57RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.81856299
587-methylguanosine mRNA capping (GO:0006370)3.81671977
59mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.81240073
60rRNA modification (GO:0000154)3.80629902
61signal transduction involved in DNA integrity checkpoint (GO:0072401)3.80103412
62signal transduction involved in DNA damage checkpoint (GO:0072422)3.80103412
637-methylguanosine RNA capping (GO:0009452)3.76310782
64RNA capping (GO:0036260)3.76310782
65transcription from RNA polymerase I promoter (GO:0006360)3.75279366
66signal transduction involved in cell cycle checkpoint (GO:0072395)3.75224654
67telomere maintenance via semi-conservative replication (GO:0032201)3.72600044
68establishment of protein localization to mitochondrial membrane (GO:0090151)3.72526400
69antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.71393625
70hydrogen ion transmembrane transport (GO:1902600)3.70392657
71rRNA metabolic process (GO:0016072)3.68213388
72spliceosomal snRNP assembly (GO:0000387)3.66458490
73protein deneddylation (GO:0000338)3.66232846
74ATP biosynthetic process (GO:0006754)3.65966106
75cellular component biogenesis (GO:0044085)3.64012866
76DNA strand elongation involved in DNA replication (GO:0006271)3.61210287
77positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.60386197
78protein complex disassembly (GO:0043241)3.60296147
79inner mitochondrial membrane organization (GO:0007007)3.59864093
80energy coupled proton transport, down electrochemical gradient (GO:0015985)3.58238651
81ATP synthesis coupled proton transport (GO:0015986)3.58238651
82purine nucleoside triphosphate biosynthetic process (GO:0009145)3.57599005
83ribosome assembly (GO:0042255)3.57153338
84ribosome biogenesis (GO:0042254)3.56741544
85pseudouridine synthesis (GO:0001522)3.56491464
86mannosylation (GO:0097502)3.55595095
87L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.54466351
88purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.54154917
89antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.51448246
90platelet dense granule organization (GO:0060155)3.50771537
91transcription-coupled nucleotide-excision repair (GO:0006283)3.47758367
92telomere maintenance via recombination (GO:0000722)3.45786210
93water-soluble vitamin biosynthetic process (GO:0042364)3.44204556
94positive regulation of ligase activity (GO:0051351)3.44138953
95macromolecular complex disassembly (GO:0032984)3.43794714
96mitotic metaphase plate congression (GO:0007080)3.42521850
97DNA strand elongation (GO:0022616)3.42480671
98regulation of mitochondrial translation (GO:0070129)3.42327533
99transcription initiation from RNA polymerase I promoter (GO:0006361)3.40633277
100proton transport (GO:0015992)3.38219457
101spliceosomal complex assembly (GO:0000245)3.33310607
102DNA replication checkpoint (GO:0000076)3.32767685
103hydrogen transport (GO:0006818)3.32064590
104protein-cofactor linkage (GO:0018065)3.31592832
105maturation of 5.8S rRNA (GO:0000460)3.28373808
106L-methionine salvage (GO:0071267)3.20857843
107L-methionine biosynthetic process (GO:0071265)3.20857843
108amino acid salvage (GO:0043102)3.20857843
109positive regulation of cell cycle arrest (GO:0071158)3.19467416
110deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.18730717
111regulation of ubiquitin-protein transferase activity (GO:0051438)3.15924154
112DNA replication initiation (GO:0006270)3.14572483
113base-excision repair, AP site formation (GO:0006285)3.13476943
114aldehyde catabolic process (GO:0046185)3.12960139
115nuclear-transcribed mRNA catabolic process (GO:0000956)3.11629518
116mitotic recombination (GO:0006312)3.10919798
117ribonucleoside triphosphate biosynthetic process (GO:0009201)3.10788246
118oxidative phosphorylation (GO:0006119)3.10730132
119intracellular protein transmembrane import (GO:0044743)3.09098619
120protein localization to mitochondrion (GO:0070585)3.08541133
121DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.07901867
122CENP-A containing nucleosome assembly (GO:0034080)3.05355189
123guanosine-containing compound biosynthetic process (GO:1901070)3.04617935
124regulation of ligase activity (GO:0051340)3.04226591
125exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.02972532
126establishment of protein localization to mitochondrion (GO:0072655)3.01477251
127GTP biosynthetic process (GO:0006183)3.00945123
128protein targeting to mitochondrion (GO:0006626)3.00935142
129protein targeting to membrane (GO:0006612)2.99116311
130G1/S transition of mitotic cell cycle (GO:0000082)2.98496003
131cell cycle G1/S phase transition (GO:0044843)2.98496003
132viral mRNA export from host cell nucleus (GO:0046784)2.97933445
133preassembly of GPI anchor in ER membrane (GO:0016254)2.96127475
134peptidyl-histidine modification (GO:0018202)2.92575772
135ubiquinone biosynthetic process (GO:0006744)2.90427071
136pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.90386270
137sequestering of actin monomers (GO:0042989)2.88649689
138rRNA methylation (GO:0031167)2.87308202
139nucleoside triphosphate biosynthetic process (GO:0009142)2.85402704
140epithelial cilium movement (GO:0003351)2.83833550
141DNA damage response, detection of DNA damage (GO:0042769)2.82894936
142mitochondrial transport (GO:0006839)2.81039962
143deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.80779814
144tRNA processing (GO:0008033)2.79292677
145C-terminal protein lipidation (GO:0006501)2.75838739

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse4.44175991
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.40708321
3E2F7_22180533_ChIP-Seq_HELA_Human4.11433594
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.92294808
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.84472541
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.81831629
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.56487654
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.50299158
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.34328519
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.25499460
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.22694686
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.14986136
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.92823848
14* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89335407
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.87629501
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.83403363
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.82087524
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.68119091
19* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.53617580
20* VDR_23849224_ChIP-Seq_CD4+_Human2.51979836
21ZNF274_21170338_ChIP-Seq_K562_Hela2.48977950
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.46073239
23XRN2_22483619_ChIP-Seq_HELA_Human2.44847220
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.40086552
25DCP1A_22483619_ChIP-Seq_HELA_Human2.39465352
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.30064103
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.25758160
28CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.23454028
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.18932683
30FOXP3_21729870_ChIP-Seq_TREG_Human2.12697969
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.11460755
32FOXM1_23109430_ChIP-Seq_U2OS_Human2.10245443
33THAP11_20581084_ChIP-Seq_MESCs_Mouse2.09053346
34YY1_21170310_ChIP-Seq_MESCs_Mouse2.00036863
35VDR_22108803_ChIP-Seq_LS180_Human1.99085341
36* TTF2_22483619_ChIP-Seq_HELA_Human1.98527081
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.93369875
38MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92597184
39* GABP_19822575_ChIP-Seq_HepG2_Human1.92507350
40* ELK1_19687146_ChIP-ChIP_HELA_Human1.89201816
41* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.87129673
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86487502
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.84112319
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.84058004
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.82777064
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.70383016
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67534223
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65779252
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60024998
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.58327365
51* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56560908
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52342096
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51050017
54* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48548618
55EWS_26573619_Chip-Seq_HEK293_Human1.47587363
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.47512985
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.46441199
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.45491688
59* ELK1_22589737_ChIP-Seq_MCF10A_Human1.41802643
60CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.38565028
61IGF1R_20145208_ChIP-Seq_DFB_Human1.37231220
62EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.34612754
63TP53_22573176_ChIP-Seq_HFKS_Human1.33754729
64* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33606968
65BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.32044045
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31576500
67AR_21909140_ChIP-Seq_LNCAP_Human1.31032765
68FUS_26573619_Chip-Seq_HEK293_Human1.30706595
69ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.30168415
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.30035278
71ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29262441
72CIITA_25753668_ChIP-Seq_RAJI_Human1.27228089
73KDM5A_27292631_Chip-Seq_BREAST_Human1.22386412
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.21375537
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19226391
76SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.18453081
77SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16623014
78E2F1_21310950_ChIP-Seq_MCF-7_Human1.16239734
79* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15922274
80AR_20517297_ChIP-Seq_VCAP_Human1.15222646
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14442769
82CTBP1_25329375_ChIP-Seq_LNCAP_Human1.12762964
83SOX2_18692474_ChIP-Seq_MEFs_Mouse1.10479516
84TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09888288
85OCT4_18692474_ChIP-Seq_MEFs_Mouse1.09790784
86SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.08682003
87* FOXA1_25329375_ChIP-Seq_VCAP_Human1.07519415
88* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.07519415
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07433164
90CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.05938059
91SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.05432181
92PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03811460
93NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.03429220
94* PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.03217384
95NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02607959
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02441170
97CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01406667
98DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00238417
99TFEB_21752829_ChIP-Seq_HELA_Human0.98752452
100* SOX2_19829295_ChIP-Seq_ESCs_Human0.98745668
101* NANOG_19829295_ChIP-Seq_ESCs_Human0.98745668
102EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.98155150
103CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97956848
104P300_19829295_ChIP-Seq_ESCs_Human0.97241897
105PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97179545
106ZFP57_27257070_Chip-Seq_ESCs_Mouse0.96804546
107* MYC_18940864_ChIP-ChIP_HL60_Human0.96722041
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.95993876
109KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95409560
110NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94596409
111TP63_19390658_ChIP-ChIP_HaCaT_Human0.94580329
112* GATA3_21878914_ChIP-Seq_MCF-7_Human0.94343156
113ERG_20517297_ChIP-Seq_VCAP_Human0.93985313
114NCOR_22424771_ChIP-Seq_293T_Human0.93238101
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93031214
116GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92585420
117CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.92228069
118HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90656041
119NANOG_20526341_ChIP-Seq_ESCs_Human0.89902603
120ETV2_25802403_ChIP-Seq_MESCs_Mouse0.89882347
121SOX2_16153702_ChIP-ChIP_HESCs_Human0.89258976
122POU5F1_16153702_ChIP-ChIP_HESCs_Human0.88258127
123* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88172855
124HTT_18923047_ChIP-ChIP_STHdh_Human0.87826698
125POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87691569
126RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87416910
127E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.85982283
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85227710
129MYC_19829295_ChIP-Seq_ESCs_Human0.84842609
130* SPI1_23547873_ChIP-Seq_NB4_Human0.84765247
131ERA_21632823_ChIP-Seq_H3396_Human0.84356925
132SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84084941
133CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83931837
134HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.83471680
135IRF1_19129219_ChIP-ChIP_H3396_Human0.83305221
136NANOG_18692474_ChIP-Seq_MEFs_Mouse0.83253018
137ER_23166858_ChIP-Seq_MCF-7_Human0.82162414
138DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80004634
139NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.79660332
140KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.79462196
141CTCF_18555785_ChIP-Seq_MESCs_Mouse0.77291597

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.40372396
2MP0004957_abnormal_blastocyst_morpholog4.25745620
3MP0003806_abnormal_nucleotide_metabolis3.48863412
4MP0003111_abnormal_nucleus_morphology3.34976319
5MP0003077_abnormal_cell_cycle3.29871095
6MP0000372_irregular_coat_pigmentation3.26053666
7MP0010094_abnormal_chromosome_stability3.23215525
8MP0008058_abnormal_DNA_repair3.11272433
9MP0008057_abnormal_DNA_replication2.80991889
10MP0008932_abnormal_embryonic_tissue2.76909847
11MP0003786_premature_aging2.74386573
12MP0009379_abnormal_foot_pigmentation2.66446181
13MP0003718_maternal_effect2.65463239
14MP0006072_abnormal_retinal_apoptosis2.63402270
15MP0002837_dystrophic_cardiac_calcinosis2.57629219
16MP0003186_abnormal_redox_activity2.46332775
17MP0008007_abnormal_cellular_replicative2.36874306
18MP0003195_calcinosis2.34142264
19MP0001529_abnormal_vocalization2.23806419
20MP0006292_abnormal_olfactory_placode2.10949555
21MP0002938_white_spotting2.10190373
22MP0002102_abnormal_ear_morphology2.07224732
23MP0005084_abnormal_gallbladder_morpholo1.98654928
24MP0003011_delayed_dark_adaptation1.90863535
25MP0005645_abnormal_hypothalamus_physiol1.88679870
26MP0008995_early_reproductive_senescence1.83396409
27MP0003123_paternal_imprinting1.80538849
28MP0008260_abnormal_autophagy1.80163168
29MP0005551_abnormal_eye_electrophysiolog1.77215641
30MP0002736_abnormal_nociception_after1.75961205
31MP0004142_abnormal_muscle_tone1.71354407
32MP0005253_abnormal_eye_physiology1.69623199
33MP0001968_abnormal_touch/_nociception1.67656644
34MP0002653_abnormal_ependyma_morphology1.66874054
35MP0006036_abnormal_mitochondrial_physio1.64462873
36MP0008872_abnormal_physiological_respon1.63048708
37MP0005379_endocrine/exocrine_gland_phen1.61694880
38MP0008875_abnormal_xenobiotic_pharmacok1.60782136
39MP0005646_abnormal_pituitary_gland1.60612487
40MP0003315_abnormal_perineum_morphology1.56636390
41MP0005075_abnormal_melanosome_morpholog1.56112824
42MP0001730_embryonic_growth_arrest1.53585027
43MP0001905_abnormal_dopamine_level1.52940110
44MP0003567_abnormal_fetal_cardiomyocyte1.52103577
45MP0002638_abnormal_pupillary_reflex1.51002400
46MP0003941_abnormal_skin_development1.50808630
47MP0004133_heterotaxia1.50696721
48MP0009333_abnormal_splenocyte_physiolog1.50229947
49MP0003950_abnormal_plasma_membrane1.48959456
50MP0003136_yellow_coat_color1.48798975
51MP0000566_synostosis1.47450613
52MP0001764_abnormal_homeostasis1.47243578
53MP0001853_heart_inflammation1.46350156
54MP0010386_abnormal_urinary_bladder1.43054096
55MP0001984_abnormal_olfaction1.42042061
56MP0000490_abnormal_crypts_of1.40237933
57MP0000350_abnormal_cell_proliferation1.37518803
58MP0001542_abnormal_bone_strength1.33977198
59MP0003880_abnormal_central_pattern1.31799095
60MP0009697_abnormal_copulation1.31467570
61MP0001293_anophthalmia1.29034578
62MP0002160_abnormal_reproductive_system1.29031100
63MP0002132_abnormal_respiratory_system1.25349115
64MP0006276_abnormal_autonomic_nervous1.22605184
65MP0009046_muscle_twitch1.22340767
66MP0000631_abnormal_neuroendocrine_gland1.21591290
67MP0002396_abnormal_hematopoietic_system1.21555927
68MP0006035_abnormal_mitochondrial_morpho1.20855961
69MP0003646_muscle_fatigue1.20279053
70MP0000313_abnormal_cell_death1.19600564
71MP0002148_abnormal_hypersensitivity_rea1.17732104
72MP0002876_abnormal_thyroid_physiology1.16918807
73MP0005389_reproductive_system_phenotype1.14687063
74MP0003787_abnormal_imprinting1.14684313
75MP0005174_abnormal_tail_pigmentation1.13658673
76MP0002234_abnormal_pharynx_morphology1.11238098
77MP0002080_prenatal_lethality1.10426794
78MP0009745_abnormal_behavioral_response1.09878467
79MP0000358_abnormal_cell_content/1.09185539
80MP0005380_embryogenesis_phenotype1.09041738
81MP0001672_abnormal_embryogenesis/_devel1.09041738
82MP0010030_abnormal_orbit_morphology1.06937402
83MP0001485_abnormal_pinna_reflex1.06926714
84MP0005410_abnormal_fertilization1.05931725
85MP0001697_abnormal_embryo_size1.05857431
86MP0003121_genomic_imprinting1.02916504
87MP0005266_abnormal_metabolism1.02820209
88MP0003122_maternal_imprinting1.01827082
89MP0002822_catalepsy1.01787425
90MP0002095_abnormal_skin_pigmentation0.96827410
91MP0009840_abnormal_foam_cell0.96685465
92MP0002090_abnormal_vision0.94787241
93MP0009785_altered_susceptibility_to0.94300524
94MP0002019_abnormal_tumor_incidence0.92974303
95MP0001835_abnormal_antigen_presentation0.92808868
96MP0001919_abnormal_reproductive_system0.92105095
97MP0003984_embryonic_growth_retardation0.91569040
98MP0002088_abnormal_embryonic_growth/wei0.89808276
99MP0005395_other_phenotype0.89718947
100MP0002272_abnormal_nervous_system0.89511326
101MP0001727_abnormal_embryo_implantation0.89461236
102MP0005499_abnormal_olfactory_system0.89454626
103MP0005394_taste/olfaction_phenotype0.89454626
104MP0009053_abnormal_anal_canal0.89331206
105MP0004742_abnormal_vestibular_system0.89183414
106MP0000689_abnormal_spleen_morphology0.88944211
107MP0005636_abnormal_mineral_homeostasis0.87861604
108MP0001986_abnormal_taste_sensitivity0.86074747
109MP0001324_abnormal_eye_pigmentation0.85760274
110MP0002085_abnormal_embryonic_tissue0.85502165
111MP0001929_abnormal_gametogenesis0.84870804
112MP0002210_abnormal_sex_determination0.84280791
113MP0004043_abnormal_pH_regulation0.84019394
114MP0002277_abnormal_respiratory_mucosa0.83231482
115MP0002722_abnormal_immune_system0.82316324
116MP0002693_abnormal_pancreas_physiology0.80481595
117MP0005195_abnormal_posterior_eye0.79213380
118MP0008789_abnormal_olfactory_epithelium0.79150686
119MP0000026_abnormal_inner_ear0.77850383
120MP0005408_hypopigmentation0.77535104
121MP0004782_abnormal_surfactant_physiolog0.76880644
122MP0003283_abnormal_digestive_organ0.76808988
123MP0002557_abnormal_social/conspecific_i0.75593515
124MP0005397_hematopoietic_system_phenotyp0.75290355
125MP0001545_abnormal_hematopoietic_system0.75290355
126MP0000653_abnormal_sex_gland0.74481291
127MP0004147_increased_porphyrin_level0.74259452
128MP0001119_abnormal_female_reproductive0.73720117
129MP0005376_homeostasis/metabolism_phenot0.73625307
130MP0002735_abnormal_chemical_nociception0.73263018
131MP0001756_abnormal_urination0.72522104
132MP0002282_abnormal_trachea_morphology0.72179720
133MP0000750_abnormal_muscle_regeneration0.71783889
134MP0003119_abnormal_digestive_system0.71781307
135MP0003137_abnormal_impulse_conducting0.71577451
136MP0001145_abnormal_male_reproductive0.71572861
137MP0004885_abnormal_endolymph0.71160182
138MP0005377_hearing/vestibular/ear_phenot0.71153572
139MP0003878_abnormal_ear_physiology0.71153572
140MP0002139_abnormal_hepatobiliary_system0.71055999
141MP0002751_abnormal_autonomic_nervous0.70894256
142MP0004145_abnormal_muscle_electrophysio0.70328030
143MP0005671_abnormal_response_to0.70157159
144MP0005391_vision/eye_phenotype0.69390726
145MP0005332_abnormal_amino_acid0.68411347
146MP0002332_abnormal_exercise_endurance0.67957341
147MP0002086_abnormal_extraembryonic_tissu0.67275518
148MP0001286_abnormal_eye_development0.66036171
149MP0003936_abnormal_reproductive_system0.65919020
150MP0008877_abnormal_DNA_methylation0.65085212
151MP0002084_abnormal_developmental_patter0.64844269
152MP0002111_abnormal_tail_morphology0.64589857
153MP0002163_abnormal_gland_morphology0.63403105
154MP0002429_abnormal_blood_cell0.62057475
155MP0004019_abnormal_vitamin_homeostasis0.59170988
156MP0002398_abnormal_bone_marrow0.58241840
157MP0005501_abnormal_skin_physiology0.57215998
158MP0005025_abnormal_response_to0.55951962
159MP0004381_abnormal_hair_follicle0.54311579
160MP0004084_abnormal_cardiac_muscle0.54113864

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.94421103
2Reticulocytopenia (HP:0001896)4.81501984
3Abnormal number of erythroid precursors (HP:0012131)4.31245262
4Acute necrotizing encephalopathy (HP:0006965)4.30786098
5Mitochondrial inheritance (HP:0001427)3.90796317
63-Methylglutaconic aciduria (HP:0003535)3.85637417
7Macrocytic anemia (HP:0001972)3.80246138
8Abnormal mitochondria in muscle tissue (HP:0008316)3.78219596
9Hepatocellular necrosis (HP:0001404)3.74886186
10Cerebral hypomyelination (HP:0006808)3.56395267
11Acute encephalopathy (HP:0006846)3.54313809
12Hepatic necrosis (HP:0002605)3.48876274
13Increased CSF lactate (HP:0002490)3.47708891
14Increased hepatocellular lipid droplets (HP:0006565)3.43115376
15Aplasia/Hypoplasia of the sacrum (HP:0008517)3.31936490
16Progressive macrocephaly (HP:0004481)3.31197166
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.29637741
18Birth length less than 3rd percentile (HP:0003561)3.26615946
19Oral leukoplakia (HP:0002745)3.26427024
20Breast hypoplasia (HP:0003187)3.23570237
21Pancreatic fibrosis (HP:0100732)3.18921161
22Abnormality of midbrain morphology (HP:0002418)3.18141710
23Molar tooth sign on MRI (HP:0002419)3.18141710
24Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.15582046
25Pallor (HP:0000980)3.09582143
26Renal Fanconi syndrome (HP:0001994)3.08054417
27Lipid accumulation in hepatocytes (HP:0006561)3.05492849
28Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.99277376
29Increased serum lactate (HP:0002151)2.95055795
30Decreased activity of mitochondrial respiratory chain (HP:0008972)2.90499668
31Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.90499668
32Rough bone trabeculation (HP:0100670)2.87830710
33True hermaphroditism (HP:0010459)2.87530391
34Degeneration of anterior horn cells (HP:0002398)2.78649583
35Abnormality of the anterior horn cell (HP:0006802)2.78649583
36Cerebral edema (HP:0002181)2.75263835
37Aplastic anemia (HP:0001915)2.68003053
38Exertional dyspnea (HP:0002875)2.67190970
39Multiple enchondromatosis (HP:0005701)2.66667693
40Nephronophthisis (HP:0000090)2.63563556
41Medial flaring of the eyebrow (HP:0010747)2.63031715
42Exercise intolerance (HP:0003546)2.60833847
43Methylmalonic acidemia (HP:0002912)2.53089512
44Methylmalonic aciduria (HP:0012120)2.51052016
45Type I transferrin isoform profile (HP:0003642)2.46911938
46Lactic acidosis (HP:0003128)2.46466470
47Absent thumb (HP:0009777)2.45298286
48Carpal bone hypoplasia (HP:0001498)2.44534119
49Hyperglycinemia (HP:0002154)2.42369821
50Glycosuria (HP:0003076)2.41678850
51Abnormality of urine glucose concentration (HP:0011016)2.41678850
52Cleft eyelid (HP:0000625)2.41444862
53Respiratory failure (HP:0002878)2.40840730
54Patellar aplasia (HP:0006443)2.36091381
55Abnormality of glycolysis (HP:0004366)2.34524041
56Increased serum pyruvate (HP:0003542)2.34524041
57Meckel diverticulum (HP:0002245)2.33878272
58Abnormality of the preputium (HP:0100587)2.32728510
59Respiratory difficulties (HP:0002880)2.32372458
60Congenital ichthyosiform erythroderma (HP:0007431)2.30638333
61Abnormal protein glycosylation (HP:0012346)2.29532284
62Abnormal glycosylation (HP:0012345)2.29532284
63Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.29532284
64Abnormal protein N-linked glycosylation (HP:0012347)2.29532284
65CNS demyelination (HP:0007305)2.29025502
66Generalized aminoaciduria (HP:0002909)2.23174580
67Increased intramyocellular lipid droplets (HP:0012240)2.22623022
68Aplasia/Hypoplasia of the patella (HP:0006498)2.22254614
69Congenital stationary night blindness (HP:0007642)2.21310756
70Microvesicular hepatic steatosis (HP:0001414)2.20632107
71Sparse eyelashes (HP:0000653)2.19677963
72Premature ovarian failure (HP:0008209)2.19651532
73Colon cancer (HP:0003003)2.19119437
74Secondary amenorrhea (HP:0000869)2.17385467
75Abnormality of the ileum (HP:0001549)2.16845240
76Triphalangeal thumb (HP:0001199)2.16072657
77Abnormality of the renal medulla (HP:0100957)2.15120768
78Cellular immunodeficiency (HP:0005374)2.14821133
79Absent radius (HP:0003974)2.14760057
80Poor head control (HP:0002421)2.14410486
81Microretrognathia (HP:0000308)2.13778202
82Abnormality of the renal cortex (HP:0011035)2.13434478
83Abnormal trabecular bone morphology (HP:0100671)2.12862647
84Abnormality of the labia minora (HP:0012880)2.11406984
85Leukodystrophy (HP:0002415)2.10563068
86Lethargy (HP:0001254)2.05590565
87Premature graying of hair (HP:0002216)2.05336830
88Pancytopenia (HP:0001876)2.04716500
89Sclerocornea (HP:0000647)2.03947311
90CNS hypomyelination (HP:0003429)2.02654531
91Abnormality of dicarboxylic acid metabolism (HP:0010995)2.02254014
92Dicarboxylic aciduria (HP:0003215)2.02254014
93Bone marrow hypocellularity (HP:0005528)2.02027282
94Congenital primary aphakia (HP:0007707)2.01274543
95Hypoplasia of the radius (HP:0002984)2.00249968
96Pancreatic cysts (HP:0001737)1.98902945
97Trismus (HP:0000211)1.98870640
98Aplasia involving forearm bones (HP:0009822)1.98240599
99Absent forearm bone (HP:0003953)1.98240599
100Optic disc pallor (HP:0000543)1.97878508
101Hypothermia (HP:0002045)1.97269130
102Large for gestational age (HP:0001520)1.97056812
103Abnormal rod and cone electroretinograms (HP:0008323)1.96769913
104Selective tooth agenesis (HP:0001592)1.96612919
105Gait imbalance (HP:0002141)1.95343103
106Abnormal respiratory epithelium morphology (HP:0012253)1.94753742
107Abnormal respiratory motile cilium morphology (HP:0005938)1.94753742
108Pendular nystagmus (HP:0012043)1.93976670
109Prolonged neonatal jaundice (HP:0006579)1.93893512
110Renal cortical cysts (HP:0000803)1.93497121
111Nausea (HP:0002018)1.93421873
112Stenosis of the external auditory canal (HP:0000402)1.92953552
113Abnormality of the umbilical cord (HP:0010881)1.92533337
114Cystic liver disease (HP:0006706)1.92281178
115Nephrogenic diabetes insipidus (HP:0009806)1.92088893
116Hyperphosphaturia (HP:0003109)1.90963890
117Abnormality of renal resorption (HP:0011038)1.89665737
118Congenital, generalized hypertrichosis (HP:0004540)1.89320795
119Aplasia/hypoplasia of the uterus (HP:0008684)1.88289591
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.87398749
121Aplasia/Hypoplasia of the uvula (HP:0010293)1.87195707
122Thrombocytosis (HP:0001894)1.86071827
123Impulsivity (HP:0100710)1.86008308
124Emotional lability (HP:0000712)1.85655698
125Horseshoe kidney (HP:0000085)1.85103999
126Aplasia/Hypoplasia involving the musculature (HP:0001460)1.83556546
127Abnormality of the pons (HP:0007361)1.83369754
128Increased muscle lipid content (HP:0009058)1.81833494
129Type II lissencephaly (HP:0007260)1.81551765
130Abnormal biliary tract physiology (HP:0012439)1.80702583
131Bile duct proliferation (HP:0001408)1.80702583
132Spastic paraparesis (HP:0002313)1.80437704
133X-linked dominant inheritance (HP:0001423)1.78523739
134Abnormality of the fetal cardiovascular system (HP:0010948)1.78480196
135Abnormal umbilical cord blood vessels (HP:0011403)1.78480196
136Single umbilical artery (HP:0001195)1.78480196
137Decreased electroretinogram (ERG) amplitude (HP:0000654)1.78408322
138Anencephaly (HP:0002323)1.78349422
139Entropion (HP:0000621)1.77916672
140Intestinal atresia (HP:0011100)1.77457655
141Severe visual impairment (HP:0001141)1.76948654
14211 pairs of ribs (HP:0000878)1.76364331
143Abnormal ciliary motility (HP:0012262)1.75622860
144Aplasia/Hypoplasia of the tongue (HP:0010295)1.75165165
145Death in infancy (HP:0001522)1.75086054
146Reduced antithrombin III activity (HP:0001976)1.74719740
147Hypoplasia of the pons (HP:0012110)1.74264050
148Chromsome breakage (HP:0040012)1.72326643
149Male pseudohermaphroditism (HP:0000037)1.70595896
150Ketosis (HP:0001946)1.69896330
151Ketoacidosis (HP:0001993)1.67087764
152Abolished electroretinogram (ERG) (HP:0000550)1.66822954
153Abnormality of methionine metabolism (HP:0010901)1.66333349
154Hyperglycinuria (HP:0003108)1.66073321
155Abnormality of aspartate family amino acid metabolism (HP:0010899)1.65888492
156Abnormal respiratory motile cilium physiology (HP:0012261)1.64447146

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.24595736
2BUB14.98850755
3NME24.03658198
4WEE13.73913347
5EIF2AK13.49010467
6MAP4K23.19627747
7STK163.07084748
8PLK42.53031918
9TLK12.46021496
10WNK32.44455596
11EPHA22.42072850
12NUAK12.36067925
13FRK2.32862763
14TAOK32.32372298
15EIF2AK32.23977156
16SRPK12.17861511
17VRK12.14936188
18TSSK62.04792817
19BCKDK1.99807293
20PIM21.93360996
21ZAK1.83900432
22TRIM281.82517034
23GRK11.76685554
24BRAF1.69636511
25BRSK21.66219779
26PBK1.62127572
27CDC71.52991524
28NME11.51963205
29ACVR1B1.49925550
30IRAK31.49890124
31NEK21.48739690
32TTK1.47280093
33PLK11.47044598
34RPS6KB21.37818144
35AURKB1.35840873
36NEK11.32924237
37MKNK11.26513545
38TAF11.25346227
39AURKA1.21838361
40INSRR1.15926242
41CDK71.15296157
42BRSK11.13414130
43AKT31.11652114
44EIF2AK21.11077733
45CSNK1G31.10359521
46MKNK21.10022517
47PLK31.06258335
48TESK21.05277676
49WNK41.04532620
50DYRK31.04425396
51MYLK1.03909499
52TNIK1.00289622
53MST40.98466583
54CSNK1G10.95992203
55CSNK1G20.94068198
56ARAF0.93947549
57RPS6KA50.92654758
58TGFBR10.91797541
59MAPKAPK30.91712492
60CASK0.90852261
61MAP3K120.90847242
62MAP2K70.90574390
63MAP3K80.90422004
64RPS6KA40.87763272
65DYRK20.87507194
66MAPK130.87118842
67MAP3K40.86127617
68ATR0.85402110
69STK240.83871460
70TESK10.83338425
71BLK0.81758438
72CSNK2A10.81652945
73MAP3K110.80579311
74LIMK10.78284331
75PHKG10.77744661
76PHKG20.77744661
77STK40.76335866
78MAP2K60.76134605
79PASK0.75978674
80PINK10.75631429
81PIM10.75561150
82MUSK0.75471751
83PDK20.74429097
84STK38L0.74198828
85CSNK1A1L0.73957119
86IRAK40.73852427
87NEK90.72967232
88OXSR10.71572565
89KDR0.71301412
90IKBKB0.71213124
91CSNK2A20.69908875
92TAOK20.69642911
93PAK10.69327276
94PRKCI0.69238818
95KIT0.66371950
96OBSCN0.65905044
97PRKCG0.65733730
98TIE10.64695732
99ILK0.63352387
100CHEK20.63271211
101CDK190.62684250
102ADRBK10.61822138
103PAK40.60080477
104MAP2K20.59516102
105ABL20.59443575
106IRAK20.57812239
107CDK80.57100591
108PLK20.55002450
109PRKCE0.54984046
110DAPK10.49293375
111CHEK10.49137906
112TXK0.46991665
113STK100.46002259
114CCNB10.45087266
115BMPR1B0.44755471
116FGFR20.44140725
117PAK30.43348989
118CSNK1A10.43225974
119ADRBK20.42504448
120MAP3K30.41530351
121BCR0.41201761
122DAPK30.40592461
123EPHB20.39953523
124STK390.39863722
125DAPK20.38860351
126FLT30.38806580
127MAPKAPK50.37621108
128PRKCQ0.37470852
129LRRK20.37400408
130YES10.37166063
131TNK20.36838755
132PNCK0.35999696
133GRK70.35553682
134PRKACA0.35443608
135MAP4K10.34268152
136MATK0.34227378
137MAPKAPK20.32835459
138MARK30.32615040
139CDK20.32578672
140GRK50.32555497
141CLK10.29633075
142CHUK0.28307930

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.01038817
2Proteasome_Homo sapiens_hsa030504.69673423
3RNA polymerase_Homo sapiens_hsa030204.07949953
4DNA replication_Homo sapiens_hsa030303.47587619
5Mismatch repair_Homo sapiens_hsa034303.15996369
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.92470772
7Spliceosome_Homo sapiens_hsa030402.65986998
8Pyrimidine metabolism_Homo sapiens_hsa002402.60299377
9Oxidative phosphorylation_Homo sapiens_hsa001902.51421605
10Homologous recombination_Homo sapiens_hsa034402.46841357
11Nucleotide excision repair_Homo sapiens_hsa034202.44613397
12Parkinsons disease_Homo sapiens_hsa050122.30460990
13RNA transport_Homo sapiens_hsa030132.25042387
14Base excision repair_Homo sapiens_hsa034102.08472770
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.95496355
16Protein export_Homo sapiens_hsa030601.91549311
17Basal transcription factors_Homo sapiens_hsa030221.89508250
18Huntingtons disease_Homo sapiens_hsa050161.84426114
19One carbon pool by folate_Homo sapiens_hsa006701.78506677
20Fanconi anemia pathway_Homo sapiens_hsa034601.70895153
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.70029789
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.67135674
23Purine metabolism_Homo sapiens_hsa002301.45405158
24Cell cycle_Homo sapiens_hsa041101.45270006
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.42457919
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.41733972
27RNA degradation_Homo sapiens_hsa030181.41339691
28Folate biosynthesis_Homo sapiens_hsa007901.39180418
29Maturity onset diabetes of the young_Homo sapiens_hsa049501.38252427
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36882791
31Alzheimers disease_Homo sapiens_hsa050101.31697205
32Butanoate metabolism_Homo sapiens_hsa006501.28237814
33Glutathione metabolism_Homo sapiens_hsa004801.13233927
34p53 signaling pathway_Homo sapiens_hsa041151.10014173
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.07206290
36Regulation of autophagy_Homo sapiens_hsa041401.01017395
37Pentose phosphate pathway_Homo sapiens_hsa000300.99945189
38Non-homologous end-joining_Homo sapiens_hsa034500.98679635
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98667021
40Collecting duct acid secretion_Homo sapiens_hsa049660.97181365
41Nitrogen metabolism_Homo sapiens_hsa009100.95914254
42Epstein-Barr virus infection_Homo sapiens_hsa051690.94395439
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94067110
44Vitamin B6 metabolism_Homo sapiens_hsa007500.92535494
45Sulfur metabolism_Homo sapiens_hsa009200.92225262
46Tryptophan metabolism_Homo sapiens_hsa003800.91571928
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.89533610
48Fructose and mannose metabolism_Homo sapiens_hsa000510.88648929
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.86127003
50Sulfur relay system_Homo sapiens_hsa041220.83611762
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83372744
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.83299371
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.81838327
54Fatty acid elongation_Homo sapiens_hsa000620.80254627
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79796975
56Biosynthesis of amino acids_Homo sapiens_hsa012300.77947518
57Arachidonic acid metabolism_Homo sapiens_hsa005900.73787369
58Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69888909
592-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69322807
60mRNA surveillance pathway_Homo sapiens_hsa030150.68988497
61Metabolic pathways_Homo sapiens_hsa011000.68693691
62Carbon metabolism_Homo sapiens_hsa012000.67864170
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.66861278
64alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66849010
65Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66668719
66Cardiac muscle contraction_Homo sapiens_hsa042600.66128044
67Systemic lupus erythematosus_Homo sapiens_hsa053220.66049101
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64461543
69Caffeine metabolism_Homo sapiens_hsa002320.62893742
70Asthma_Homo sapiens_hsa053100.60473968
71Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59811973
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.59744679
73Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59391863
74Allograft rejection_Homo sapiens_hsa053300.53467223
75Type I diabetes mellitus_Homo sapiens_hsa049400.51509880
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51298304
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.51036063
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.49320998
79Galactose metabolism_Homo sapiens_hsa000520.49222197
80Legionellosis_Homo sapiens_hsa051340.48995203
81Antigen processing and presentation_Homo sapiens_hsa046120.48651685
82Phototransduction_Homo sapiens_hsa047440.44350129
83N-Glycan biosynthesis_Homo sapiens_hsa005100.43830675
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43783968
85Rheumatoid arthritis_Homo sapiens_hsa053230.42394356
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41310579
87Herpes simplex infection_Homo sapiens_hsa051680.41208667
88Fatty acid degradation_Homo sapiens_hsa000710.41175495
89Arginine and proline metabolism_Homo sapiens_hsa003300.40864954
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.38319187
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38203605
92Ether lipid metabolism_Homo sapiens_hsa005650.36870784
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36646473
94Other glycan degradation_Homo sapiens_hsa005110.36327574
95Autoimmune thyroid disease_Homo sapiens_hsa053200.35718001
96Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34658654
97Fatty acid metabolism_Homo sapiens_hsa012120.34012859
98Phenylalanine metabolism_Homo sapiens_hsa003600.33654107
99Olfactory transduction_Homo sapiens_hsa047400.33364730
100Fat digestion and absorption_Homo sapiens_hsa049750.31802899
101Peroxisome_Homo sapiens_hsa041460.31657832
102Tyrosine metabolism_Homo sapiens_hsa003500.29431142
103Selenocompound metabolism_Homo sapiens_hsa004500.27287710
104Mineral absorption_Homo sapiens_hsa049780.26967539
105Sphingolipid metabolism_Homo sapiens_hsa006000.26907175
106Pyruvate metabolism_Homo sapiens_hsa006200.26902837
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.26174191
108Vitamin digestion and absorption_Homo sapiens_hsa049770.25849626
109Linoleic acid metabolism_Homo sapiens_hsa005910.25383640
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25377634
111Retinol metabolism_Homo sapiens_hsa008300.24910963
112Primary immunodeficiency_Homo sapiens_hsa053400.24147962
113Nicotine addiction_Homo sapiens_hsa050330.23342312
114Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22792462
115Viral carcinogenesis_Homo sapiens_hsa052030.22264117
116Chemical carcinogenesis_Homo sapiens_hsa052040.20022016
117Steroid biosynthesis_Homo sapiens_hsa001000.19861944
118Thyroid cancer_Homo sapiens_hsa052160.19302605
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18592671
120Hematopoietic cell lineage_Homo sapiens_hsa046400.18157297
121Graft-versus-host disease_Homo sapiens_hsa053320.17082566
122Oocyte meiosis_Homo sapiens_hsa041140.16933163
123NF-kappa B signaling pathway_Homo sapiens_hsa040640.16128415
124Propanoate metabolism_Homo sapiens_hsa006400.15911120
125beta-Alanine metabolism_Homo sapiens_hsa004100.15628627
126Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.14096097
127HTLV-I infection_Homo sapiens_hsa051660.12924169
128Apoptosis_Homo sapiens_hsa042100.12345027

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »