CFAP126

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1GTP biosynthetic process (GO:0006183)9.10130023
2regulation of cilium movement (GO:0003352)8.53461274
3sperm motility (GO:0030317)8.29750554
4UTP biosynthetic process (GO:0006228)8.15154655
5ventricular system development (GO:0021591)8.07286215
6fusion of sperm to egg plasma membrane (GO:0007342)7.79997373
7nucleoside diphosphate phosphorylation (GO:0006165)7.71186576
8UTP metabolic process (GO:0046051)7.64385828
9intraciliary transport (GO:0042073)6.86020583
10guanosine-containing compound biosynthetic process (GO:1901070)6.70111971
11primary alcohol catabolic process (GO:0034310)6.49634014
12sperm-egg recognition (GO:0035036)6.48999669
13CTP metabolic process (GO:0046036)6.39047212
14CTP biosynthetic process (GO:0006241)6.39047212
15cell wall macromolecule catabolic process (GO:0016998)6.37436111
16cell wall macromolecule metabolic process (GO:0044036)6.37436111
17acrosome assembly (GO:0001675)6.34614223
18acrosome reaction (GO:0007340)6.30795379
19multicellular organism reproduction (GO:0032504)6.19015882
20spermatid development (GO:0007286)6.11087402
21binding of sperm to zona pellucida (GO:0007339)5.89890816
22pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.87470796
23plasma membrane fusion (GO:0045026)5.75182025
24cell-cell recognition (GO:0009988)5.73594459
25vitamin transmembrane transport (GO:0035461)5.69255294
26pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.63624417
27ethanol metabolic process (GO:0006067)5.35590138
28left/right axis specification (GO:0070986)5.34367471
29diterpenoid biosynthetic process (GO:0016102)5.29898483
30cilium organization (GO:0044782)5.22858843
31pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)5.20693901
32regulation of microtubule-based movement (GO:0060632)5.18156241
33microtubule severing (GO:0051013)5.15015866
34reproduction (GO:0000003)5.14561652
35cilium assembly (GO:0042384)4.97058109
36negative regulation of inclusion body assembly (GO:0090084)4.96776692
37single fertilization (GO:0007338)4.95711348
38pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.91883149
39cilium morphogenesis (GO:0060271)4.88704066
40tolerance induction (GO:0002507)4.66137476
41protein localization to cilium (GO:0061512)4.65903777
42microtubule bundle formation (GO:0001578)4.51682779
43organic cation transport (GO:0015695)4.51595475
44pyrimidine-containing compound transmembrane transport (GO:0072531)4.48785279
45centriole assembly (GO:0098534)4.45742464
46sperm capacitation (GO:0048240)4.40929952
47protein polyglutamylation (GO:0018095)4.39661613
48left/right pattern formation (GO:0060972)4.39356025
49glomerular epithelial cell development (GO:0072310)4.34045294
50negative regulation of B cell mediated immunity (GO:0002713)4.33002173
51negative regulation of immunoglobulin mediated immune response (GO:0002890)4.33002173
52establishment of apical/basal cell polarity (GO:0035089)4.26602962
53cellular component assembly involved in morphogenesis (GO:0010927)4.25646127
54negative regulation of T cell differentiation in thymus (GO:0033085)4.24687895
55microtubule depolymerization (GO:0007019)4.24329305
56nucleoside diphosphate metabolic process (GO:0009132)4.23053237
57male meiosis (GO:0007140)4.20813820
58spermatogenesis (GO:0007283)4.12866252
59response to xenobiotic stimulus (GO:0009410)4.11917818
60male gamete generation (GO:0048232)4.10692430
61nucleotide phosphorylation (GO:0046939)4.09792409
62fertilization (GO:0009566)4.04975331
63ethanol oxidation (GO:0006069)4.04354126
64microtubule-based movement (GO:0007018)4.01117329
65synaptonemal complex organization (GO:0070193)3.92436853
66establishment or maintenance of monopolar cell polarity (GO:0061339)3.90914494
67establishment of monopolar cell polarity (GO:0061162)3.90914494
68pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.86808238
69regulation of inclusion body assembly (GO:0090083)3.81765950
70terpenoid biosynthetic process (GO:0016114)3.80887029
71piRNA metabolic process (GO:0034587)3.79036054
72male meiosis I (GO:0007141)3.78218420
73gamete generation (GO:0007276)3.75899604
74positive regulation of tolerance induction (GO:0002645)3.71233168
75otic vesicle formation (GO:0030916)3.69651600
76regulation of interleukin-5 production (GO:0032674)3.69066229
77retinoic acid metabolic process (GO:0042573)3.66471924
78regulation of germinal center formation (GO:0002634)3.62053934
79pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.60378960
80genitalia morphogenesis (GO:0035112)3.60274409
81microtubule polymerization or depolymerization (GO:0031109)3.59195298
82spermatid nucleus differentiation (GO:0007289)3.57819203
83negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.56454461
84centriole replication (GO:0007099)3.54428435
85sensory perception of smell (GO:0007608)3.49814370
86establishment of tissue polarity (GO:0007164)3.48785787
87establishment of planar polarity (GO:0001736)3.48785787
88cytoplasmic microtubule organization (GO:0031122)3.46809328
89lung epithelium development (GO:0060428)3.43083976
90pyrimidine ribonucleotide metabolic process (GO:0009218)3.38254763
91cell projection assembly (GO:0030031)3.32883506
92lateral ventricle development (GO:0021670)3.29510480
93one-carbon compound transport (GO:0019755)3.24624365
94protein refolding (GO:0042026)3.22201985
95pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.21367304
96regulation of interleukin-13 production (GO:0032656)3.18909597
97pyrimidine ribonucleoside metabolic process (GO:0046131)3.16422258
98pyrimidine nucleotide biosynthetic process (GO:0006221)3.12606886
99purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.11309447
100exogenous drug catabolic process (GO:0042738)3.10023945
101calcium ion-dependent exocytosis (GO:0017156)3.09702608
102determination of left/right symmetry (GO:0007368)3.09547660
103lateral sprouting from an epithelium (GO:0060601)3.08721135
104germ cell development (GO:0007281)3.08001246
105synaptonemal complex assembly (GO:0007130)3.05805787
106glutathione derivative metabolic process (GO:1901685)3.05331921
107glutathione derivative biosynthetic process (GO:1901687)3.05331921
108base-excision repair, AP site formation (GO:0006285)3.03872070
109purine nucleoside triphosphate biosynthetic process (GO:0009145)3.02663986
110meiosis I (GO:0007127)3.01699183
111cellular process involved in reproduction in multicellular organism (GO:0022412)2.98662711
112multicellular organismal reproductive process (GO:0048609)2.98641883
113retinol metabolic process (GO:0042572)2.97618468
114determination of bilateral symmetry (GO:0009855)2.97227831
115pyrimidine nucleoside biosynthetic process (GO:0046134)2.96592557
116meiotic cell cycle (GO:0051321)2.94833789
117positive regulation of smoothened signaling pathway (GO:0045880)2.93126085
118primary alcohol metabolic process (GO:0034308)2.91803724
119specification of symmetry (GO:0009799)2.89627298
120retinal rod cell development (GO:0046548)2.83915005
121nucleoside triphosphate biosynthetic process (GO:0009142)2.81538312
122microtubule-based process (GO:0007017)2.80799117
123aldehyde catabolic process (GO:0046185)2.80438954
124nonmotile primary cilium assembly (GO:0035058)2.80409498
125glycerol ether metabolic process (GO:0006662)2.80154591
126organelle assembly (GO:0070925)2.75534416
127hydrogen peroxide biosynthetic process (GO:0050665)2.75371808
128ribonucleoside triphosphate biosynthetic process (GO:0009201)2.74393736
129apical protein localization (GO:0045176)2.74252908
130smoothened signaling pathway (GO:0007224)2.73703616
131O-glycan processing (GO:0016266)2.72808651
132pyrimidine nucleotide catabolic process (GO:0006244)2.70941584
133regulation of tolerance induction (GO:0002643)2.68461194
134heart looping (GO:0001947)2.67173162
135negative regulation of humoral immune response (GO:0002921)2.65141253
136embryonic camera-type eye development (GO:0031076)2.61003019
137sensory perception of chemical stimulus (GO:0007606)2.57448370
138regulation of autophagic vacuole assembly (GO:2000785)2.55943130
139ether metabolic process (GO:0018904)2.55400638
140carnitine metabolic process (GO:0009437)2.55047438
141pyrimidine-containing compound biosynthetic process (GO:0072528)2.52602658
142multicellular organismal water homeostasis (GO:0050891)2.50284547
143regulation of microtubule depolymerization (GO:0031114)2.49877878
144cell recognition (GO:0008037)2.49139641
145embryonic heart tube morphogenesis (GO:0003143)2.46361310
146cell redox homeostasis (GO:0045454)2.45699447
147excretion (GO:0007588)2.44376716
148phosphatidylcholine biosynthetic process (GO:0006656)2.44193161
149reactive oxygen species biosynthetic process (GO:1903409)2.43558288
150drug catabolic process (GO:0042737)2.40643316
151regulation of collateral sprouting (GO:0048670)2.36745050
152regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.36596538
153regulation of smoothened signaling pathway (GO:0008589)2.35348543
154phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.34743932
155hydrogen peroxide catabolic process (GO:0042744)2.32465106
156dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.27202334
157photoreceptor cell maintenance (GO:0045494)2.26407049
158axonemal dynein complex assembly (GO:0070286)15.2389649
159cilium or flagellum-dependent cell motility (GO:0001539)14.4986784
160cilium movement (GO:0003341)14.1985045
161epithelial cilium movement (GO:0003351)12.4441819
162epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.3033117
163axoneme assembly (GO:0035082)10.0911246
164motile cilium assembly (GO:0044458)10.0380551

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.50270140
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.59905330
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.76694267
4PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse3.54251270
5EZH2_22144423_ChIP-Seq_EOC_Human3.52964923
6DROSHA_22980978_ChIP-Seq_HELA_Human3.18177315
7RBPJ_22232070_ChIP-Seq_NCS_Mouse3.15750777
8FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.96602739
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.68336459
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.42595764
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.34700759
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.25919188
13SIN3B_21632747_ChIP-Seq_MESCs_Mouse2.12073754
14ESR1_20079471_ChIP-ChIP_T-47D_Human2.04000686
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.96881952
16PIAS1_25552417_ChIP-Seq_VCAP_Human1.96276384
17ERG_20517297_ChIP-Seq_VCAP_Human1.95819760
18PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.88997167
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.88046981
20STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82048351
21AHR_22903824_ChIP-Seq_MCF-7_Human1.72695306
22SOX2_22085726_ChIP-Seq_NPCs_Mouse1.71729119
23KAP1_22055183_ChIP-Seq_ESCs_Mouse1.67608012
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.67509412
25FOXM1_26456572_ChIP-Seq_MCF-7_Human1.61592605
26NR3C1_21868756_ChIP-Seq_MCF10A_Human1.61089582
27GATA3_21867929_ChIP-Seq_CD8_Mouse1.60946565
28STAT1_17558387_ChIP-Seq_HELA_Human1.60284568
29P53_21459846_ChIP-Seq_SAOS-2_Human1.58741692
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.57850920
31RUNX1_27514584_Chip-Seq_MCF-7_Human1.52979321
32SMC4_20622854_ChIP-Seq_HELA_Human1.52398638
33ARNT_22903824_ChIP-Seq_MCF-7_Human1.48849104
34WDR5_24793694_ChIP-Seq_LNCAP_Human1.48725916
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.47279445
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.46454385
37CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46318065
38TP63_23658742_ChIP-Seq_EP156T_Human1.44280339
39CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.42557732
40TAL1_26923725_Chip-Seq_HPCs_Mouse1.41527441
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.41124747
42TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.40852911
43TP53_18474530_ChIP-ChIP_U2OS_Human1.40783872
44ESR2_21235772_ChIP-Seq_MCF-7_Human1.39857193
45EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.38807072
46PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.38522481
47SOX2_27498859_Chip-Seq_STOMACH_Mouse1.38366743
48ESR1_21235772_ChIP-Seq_MCF-7_Human1.37779401
49AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.37229524
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34855000
51RAD21_21589869_ChIP-Seq_MESCs_Mouse1.32019877
52SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.32010428
53KLF5_25053715_ChIP-Seq_YYC3_Human1.31320758
54NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.30527821
55RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.30523216
56DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.30211974
57CTNNB1_20460455_ChIP-Seq_HCT116_Human1.30174125
58FOXA1_27270436_Chip-Seq_PROSTATE_Human1.28147069
59FOXA1_25329375_ChIP-Seq_VCAP_Human1.28147069
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27913289
61CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27812730
62ETV1_20927104_ChIP-Seq_GIST48_Human1.27663147
63SOX9_24532713_ChIP-Seq_HFSC_Mouse1.26282203
64TDRD3_21172665_ChIP-Seq_MCF-7_Human1.26096789
65PHF8_20622853_ChIP-Seq_HELA_Human1.25753074
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24955467
67SOX2_20726797_ChIP-Seq_SW620_Human1.24733345
68FOXA1_25552417_ChIP-Seq_VCAP_Human1.23679898
69CBP_20019798_ChIP-Seq_JUKART_Human1.23586633
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23586633
71MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.23218024
72TP63_22573176_ChIP-Seq_HFKS_Human1.22533654
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21437561
74HNFA_21074721_ChIP-Seq_CACO-2_Human1.19527585
75CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19449220
76ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.19323017
77PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.18732628
78STAT1_20625510_ChIP-Seq_HELA_Human1.18412519
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.18332585
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.18029005
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17714449
82CDX2_20551321_ChIP-Seq_CACO-2_Human1.17331455
83ELF1_20517297_ChIP-Seq_JURKAT_Human1.17088372
84CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.16004764
85FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15702323
86FLI1_21867929_ChIP-Seq_TH2_Mouse1.14036488
87AR_20517297_ChIP-Seq_VCAP_Human1.13674220
88P63_26484246_Chip-Seq_KERATINOCYTES_Human1.13226653
89CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.13116259
90GF1_26923725_Chip-Seq_HPCs_Mouse1.12162409
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10281017
92SMRT_27268052_Chip-Seq_Bcells_Human1.09953576
93MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09842065
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09088172
95TRIM28_21343339_ChIP-Seq_HEK293_Human1.08902522
96FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.07906927
97SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.07621292
98ETV2_25802403_ChIP-Seq_MESCs_Mouse1.07567938
99ZNF263_19887448_ChIP-Seq_K562_Human1.06972916
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06818169
101CTCF_27219007_Chip-Seq_Bcells_Human1.06600238
102SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06100272
103P53_22387025_ChIP-Seq_ESCs_Mouse1.05882613
104GF1B_26923725_Chip-Seq_HPCs_Mouse1.05822517
105LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.05603911
106ELK4_26923725_Chip-Seq_MESODERM_Mouse1.05393631
107NFYA_21822215_ChIP-Seq_K562_Human1.05030970
108SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.04556773
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04478325
110CRX_20693478_ChIP-Seq_RETINA_Mouse1.04310480
111RBPJ_21746931_ChIP-Seq_IB4_Human1.03965396
112KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03527458
113CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02679407
114FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02606694
115CBX2_22325352_ChIP-Seq_293T-Rex_Human1.01906814
116POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01179406
117TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01179406
118SMAD3_21741376_ChIP-Seq_EPCs_Human1.01125557
119CTCF_20526341_ChIP-Seq_ESCs_Human1.00777955
120ZFX_18555785_Chip-Seq_ESCs_Mouse1.00776944
121CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00549845
122SUZ12_27294783_Chip-Seq_ESCs_Mouse1.00321536
123CTBP1_25329375_ChIP-Seq_LNCAP_Human1.00056353
124GATA6_21074721_ChIP-Seq_CACO-2_Human1.00040805
125SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99292988
126STAT3_18555785_Chip-Seq_ESCs_Mouse0.99281590
127NANOG_18555785_Chip-Seq_ESCs_Mouse0.99220336
128TBL1_22424771_ChIP-Seq_293T_Human0.99099957
129SPI1_26923725_Chip-Seq_HPCs_Mouse0.98775864
130CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.98229318
131REST_21632747_ChIP-Seq_MESCs_Mouse0.97445148
132GATA4_25053715_ChIP-Seq_YYC3_Human0.96813818
133SMAD3_21741376_ChIP-Seq_HESCs_Human0.96551691
134SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.96496528
135GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.96304683
136YY1_22570637_ChIP-Seq_MALME-3M_Human0.95914544
137NFYB_21822215_ChIP-Seq_K562_Human0.95680739
138NANOG_20526341_ChIP-Seq_ESCs_Human0.95093175
139GATA3_21867929_ChIP-Seq_TH1_Mouse0.94604359
140CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94409004
141GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.94237724
142ESRRB_18555785_Chip-Seq_ESCs_Mouse0.94059388
143SOX2_18555785_Chip-Seq_ESCs_Mouse0.94012254
144OCT4_18555785_Chip-Seq_ESCs_Mouse0.93909197
145BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93760495
146RUNX1_26923725_Chip-Seq_HPCs_Mouse0.93646789
147TCF4_22108803_ChIP-Seq_LS180_Human0.93231346
148SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.92953980
149SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.92741098
150BCAT_22108803_ChIP-Seq_LS180_Human0.92422627
151VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.91439699
152FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.91232223
153E2F1_17053090_ChIP-ChIP_MCF-7_Human0.90619026
154TP53_16413492_ChIP-PET_HCT116_Human0.89510490
155GATA3_27048872_Chip-Seq_THYMUS_Human0.89413160
156RNF2_27304074_Chip-Seq_NSC_Mouse0.89373609
157OCT4_21477851_ChIP-Seq_ESCs_Mouse0.89352037
158CDX2_19796622_ChIP-Seq_MESCs_Mouse0.88911993
159SMAD4_21741376_ChIP-Seq_EPCs_Human0.88746795
160CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.87737890
161PHF8_20622854_ChIP-Seq_HELA_Human0.87660022
162KLF4_18555785_Chip-Seq_ESCs_Mouse0.87358992
163JARID2_20075857_ChIP-Seq_MESCs_Mouse0.86704640
164AR_21572438_ChIP-Seq_LNCaP_Human0.86474090
165PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86236430
166NFIB_24661679_ChIP-Seq_LUNG_Mouse0.85973871
167P300_18555785_Chip-Seq_ESCs_Mouse0.85858459
168SMAD4_21799915_ChIP-Seq_A2780_Human0.85855600
169PU1_27457419_Chip-Seq_LIVER_Mouse0.85701439
170CEBPB_22108803_ChIP-Seq_LS180_Human0.85453041
171VDR_22108803_ChIP-Seq_LS180_Human0.85412969
172ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.84140070
173TP63_17297297_ChIP-ChIP_HaCaT_Human0.81643091
174GATA3_24758297_ChIP-Seq_MCF-7_Human0.81467277
175STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.81399873
176SOX2_21211035_ChIP-Seq_LN229_Human0.81256422
177P68_20966046_ChIP-Seq_HELA_Human0.80950297

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.99463078
2MP0002653_abnormal_ependyma_morphology4.58811843
3MP0002132_abnormal_respiratory_system4.49036496
4MP0000566_synostosis4.14888270
5MP0001984_abnormal_olfaction4.05559294
6MP0003698_abnormal_male_reproductive3.44037021
7MP0001929_abnormal_gametogenesis3.29905464
8MP0002638_abnormal_pupillary_reflex2.74964773
9MP0002928_abnormal_bile_duct2.56551945
10MP0005379_endocrine/exocrine_gland_phen2.47961275
11MP0002102_abnormal_ear_morphology2.45259359
12MP0002160_abnormal_reproductive_system2.37070287
13MP0002277_abnormal_respiratory_mucosa2.36737143
14MP0004019_abnormal_vitamin_homeostasis2.25808253
15MP0006072_abnormal_retinal_apoptosis2.19156607
16MP0005646_abnormal_pituitary_gland2.17077751
17MP0001944_abnormal_pancreas_morphology2.10865550
18MP0005623_abnormal_meninges_morphology2.03944006
19MP0010030_abnormal_orbit_morphology1.98510045
20MP0000383_abnormal_hair_follicle1.93895188
21MP0002210_abnormal_sex_determination1.90482987
22MP0008875_abnormal_xenobiotic_pharmacok1.88134277
23MP0002909_abnormal_adrenal_gland1.78966632
24MP0003136_yellow_coat_color1.77094588
25MP0008004_abnormal_stomach_pH1.76196092
26MP0002161_abnormal_fertility/fecundity1.76012452
27MP0003186_abnormal_redox_activity1.73726831
28MP0005389_reproductive_system_phenotype1.73382113
29MP0002693_abnormal_pancreas_physiology1.69745442
30MP0001145_abnormal_male_reproductive1.69551387
31MP0001765_abnormal_ion_homeostasis1.69357909
32MP0005083_abnormal_biliary_tract1.67616789
33MP0004133_heterotaxia1.66358341
34MP0004782_abnormal_surfactant_physiolog1.65598472
35MP0000613_abnormal_salivary_gland1.63801558
36MP0002249_abnormal_larynx_morphology1.63540373
37MP0002139_abnormal_hepatobiliary_system1.61464832
38MP0010678_abnormal_skin_adnexa1.58443009
39MP0005248_abnormal_Harderian_gland1.53541840
40MP0000653_abnormal_sex_gland1.52519322
41MP0005636_abnormal_mineral_homeostasis1.50797387
42MP0009379_abnormal_foot_pigmentation1.47582872
43MP0002282_abnormal_trachea_morphology1.47576389
44MP0002734_abnormal_mechanical_nocicepti1.46310461
45MP0001346_abnormal_lacrimal_gland1.44917635
46MP0005645_abnormal_hypothalamus_physiol1.40469301
47MP0003656_abnormal_erythrocyte_physiolo1.40210296
48MP0002163_abnormal_gland_morphology1.39420715
49MP0008877_abnormal_DNA_methylation1.38113942
50MP0010386_abnormal_urinary_bladder1.38009401
51MP0000013_abnormal_adipose_tissue1.33256091
52MP0002295_abnormal_pulmonary_circulatio1.31229643
53MP0005220_abnormal_exocrine_pancreas1.30385852
54MP0002233_abnormal_nose_morphology1.28052785
55MP0004043_abnormal_pH_regulation1.27383760
56MP0010368_abnormal_lymphatic_system1.26233764
57MP0006292_abnormal_olfactory_placode1.20947765
58MP0002877_abnormal_melanocyte_morpholog1.17782626
59MP0005670_abnormal_white_adipose1.15026520
60MP0004885_abnormal_endolymph1.12482043
61MP0001879_abnormal_lymphatic_vessel1.09622756
62MP0001270_distended_abdomen1.07108715
63MP0003690_abnormal_glial_cell1.01085777
64MP0000631_abnormal_neuroendocrine_gland0.99624457
65MP0001485_abnormal_pinna_reflex0.98351870
66MP0009780_abnormal_chondrocyte_physiolo0.97019276
67MP0002234_abnormal_pharynx_morphology0.96408859
68MP0005253_abnormal_eye_physiology0.96375215
69MP0003183_abnormal_peptide_metabolism0.95987475
70MP0004858_abnormal_nervous_system0.95928256
71MP0005165_increased_susceptibility_to0.95809369
72MP0002089_abnormal_postnatal_growth/wei0.94173954
73MP0005395_other_phenotype0.93270966
74MP0008789_abnormal_olfactory_epithelium0.92684601
75MP0002735_abnormal_chemical_nociception0.92577925
76MP0009643_abnormal_urine_homeostasis0.91459555
77MP0000678_abnormal_parathyroid_gland0.91347090
78MP0009046_muscle_twitch0.90624772
79MP0005084_abnormal_gallbladder_morpholo0.90604678
80MP0001502_abnormal_circadian_rhythm0.90503585
81MP0002138_abnormal_hepatobiliary_system0.89173040
82MP0005647_abnormal_sex_gland0.86674553
83MP0000465_gastrointestinal_hemorrhage0.86117678
84MP0001986_abnormal_taste_sensitivity0.83912915
85MP0005377_hearing/vestibular/ear_phenot0.82361089
86MP0003878_abnormal_ear_physiology0.82361089
87MP0003938_abnormal_ear_development0.81419891
88MP0002405_respiratory_system_inflammati0.80402999
89MP0001919_abnormal_reproductive_system0.79037104
90MP0003283_abnormal_digestive_organ0.78759509
91MP0000049_abnormal_middle_ear0.77812659
92MP0003937_abnormal_limbs/digits/tail_de0.77297916
93MP0002078_abnormal_glucose_homeostasis0.75821758
94MP0001299_abnormal_eye_distance/0.75711352
95MP0002938_white_spotting0.74660030
96MP0005365_abnormal_bile_salt0.72659816
97MP0001324_abnormal_eye_pigmentation0.71231290
98MP0005058_abnormal_lysosome_morphology0.70790537
99MP0008995_early_reproductive_senescence0.70435319
100MP0005085_abnormal_gallbladder_physiolo0.70427834
101MP0002116_abnormal_craniofacial_bone0.69761389
102MP0002168_other_aberrant_phenotype0.69750881
103MP0005408_hypopigmentation0.69718054
104MP0003634_abnormal_glial_cell0.69355522
105MP0001970_abnormal_pain_threshold0.68649409
106MP0005167_abnormal_blood-brain_barrier0.68560282
107MP0005195_abnormal_posterior_eye0.68482555
108MP0001849_ear_inflammation0.67803587
109MP0003861_abnormal_nervous_system0.67180327
110MP0002876_abnormal_thyroid_physiology0.66880300
111MP0003879_abnormal_hair_cell0.66743362
112MP0000955_abnormal_spinal_cord0.66228364
113MP0002822_catalepsy0.65504140
114MP0005391_vision/eye_phenotype0.64646708
115MP0005551_abnormal_eye_electrophysiolog0.63323122
116MP0003942_abnormal_urinary_system0.62438150
117MP0002098_abnormal_vibrissa_morphology0.62264097
118MP0009765_abnormal_xenobiotic_induced0.60981757
119MP0005164_abnormal_response_to0.60746282
120MP0005075_abnormal_melanosome_morpholog0.60627326
121MP0001545_abnormal_hematopoietic_system0.60335862
122MP0005397_hematopoietic_system_phenotyp0.60335862
123MP0003890_abnormal_embryonic-extraembry0.60251961
124MP0005503_abnormal_tendon_morphology0.60240195
125MP0001764_abnormal_homeostasis0.59626588
126MP0010234_abnormal_vibrissa_follicle0.59502817
127MP0002136_abnormal_kidney_physiology0.59486540
128MP0003953_abnormal_hormone_level0.59407787
129MP0010155_abnormal_intestine_physiology0.58544927
130MP0001293_anophthalmia0.56341933
131MP0000026_abnormal_inner_ear0.55822900
132MP0003806_abnormal_nucleotide_metabolis0.55138038
133MP0005394_taste/olfaction_phenotype0.54655839
134MP0005499_abnormal_olfactory_system0.54655839
135MP0003115_abnormal_respiratory_system0.54442949
136MP0003724_increased_susceptibility_to0.53505560
137MP0000462_abnormal_digestive_system0.53299739
138MP0003011_delayed_dark_adaptation0.52967010
139MP0005257_abnormal_intraocular_pressure0.52756663
140MP0005266_abnormal_metabolism0.50458618
141MP0002152_abnormal_brain_morphology0.50064120
142MP0000467_abnormal_esophagus_morphology0.49859028
143MP0004883_abnormal_blood_vessel0.48915003
144MP0002752_abnormal_somatic_nervous0.48816846
145MP0002557_abnormal_social/conspecific_i0.47869850
146MP0005508_abnormal_skeleton_morphology0.47159884
147MP0003633_abnormal_nervous_system0.46950817
148MP0009703_decreased_birth_body0.46845886
149MP0001963_abnormal_hearing_physiology0.46366702
150MP0002084_abnormal_developmental_patter0.46203903
151MP0002092_abnormal_eye_morphology0.45787582
152MP0000681_abnormal_thyroid_gland0.45560663
153MP0002572_abnormal_emotion/affect_behav0.45167494
154MP0000778_abnormal_nervous_system0.44563380
155MP0002229_neurodegeneration0.44528854
156MP0002882_abnormal_neuron_morphology0.43978024

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.81136651
2Abnormal respiratory motile cilium morphology (HP:0005938)9.81136651
3Rhinitis (HP:0012384)9.67760772
4Absent/shortened dynein arms (HP:0200106)9.43974939
5Dynein arm defect of respiratory motile cilia (HP:0012255)9.43974939
6Chronic bronchitis (HP:0004469)7.77664948
7Bronchiectasis (HP:0002110)6.34371125
8Nasal polyposis (HP:0100582)5.65329959
9Abnormality of the nasal mucosa (HP:0000433)4.74375931
10Infertility (HP:0000789)4.49973538
11Bronchitis (HP:0012387)4.45530856
12Chronic sinusitis (HP:0011109)3.77974776
13True hermaphroditism (HP:0010459)3.55080829
14Recurrent sinusitis (HP:0011108)3.52697852
15Pancreatic fibrosis (HP:0100732)3.46238863
16Nephronophthisis (HP:0000090)3.39735381
17Molar tooth sign on MRI (HP:0002419)3.10616669
18Abnormality of midbrain morphology (HP:0002418)3.10616669
19Tubulointerstitial nephritis (HP:0001970)3.04059450
20Chronic otitis media (HP:0000389)3.01999538
21Recurrent otitis media (HP:0000403)2.95128846
22Medial flaring of the eyebrow (HP:0010747)2.92602777
23Abnormality of the renal medulla (HP:0100957)2.75242262
24Male infertility (HP:0003251)2.71491416
25Cystic liver disease (HP:0006706)2.65174375
26Tubulointerstitial abnormality (HP:0001969)2.60896258
27Occipital encephalocele (HP:0002085)2.60352930
28Pancreatic cysts (HP:0001737)2.55809237
29Congenital primary aphakia (HP:0007707)2.54314799
30Gait imbalance (HP:0002141)2.49378808
31Tubular atrophy (HP:0000092)2.45208952
32Tubulointerstitial fibrosis (HP:0005576)2.44705505
33Median cleft lip (HP:0000161)2.38583093
34Congenital hepatic fibrosis (HP:0002612)2.38567521
35Short nail (HP:0001799)2.36700180
36Nephrogenic diabetes insipidus (HP:0009806)2.31259913
37Recurrent bronchitis (HP:0002837)2.24108128
38Abnormality of the dental root (HP:0006486)2.23325998
39Taurodontia (HP:0000679)2.23325998
40Abnormality of permanent molar morphology (HP:0011071)2.23325998
41Bile duct proliferation (HP:0001408)2.15970053
42Abnormal biliary tract physiology (HP:0012439)2.15970053
43Postaxial foot polydactyly (HP:0001830)2.14388488
44Abnormality of the dental pulp (HP:0006479)2.09462518
45Abnormality of molar morphology (HP:0011070)2.03771130
46Abnormality of molar (HP:0011077)2.03771130
47Abnormality of dentin (HP:0010299)2.02065858
4811 pairs of ribs (HP:0000878)2.00844365
49Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.9112625
50Abnormal respiratory motile cilium physiology (HP:0012261)11.4380128
51Abnormal ciliary motility (HP:0012262)10.9384411
52Aplasia/Hypoplasia of the tongue (HP:0010295)1.97423295
53Bifid tongue (HP:0010297)1.93317856
54Genital tract atresia (HP:0001827)1.89507084
55Facial cleft (HP:0002006)1.87937016
56Vaginal atresia (HP:0000148)1.86383554
57Bell-shaped thorax (HP:0001591)1.83608024
58Poor coordination (HP:0002370)1.80078526
59Stage 5 chronic kidney disease (HP:0003774)1.78835183
60Absent frontal sinuses (HP:0002688)1.74114689
61Asplenia (HP:0001746)1.73281429
62Postaxial hand polydactyly (HP:0001162)1.73167067
63Nephropathy (HP:0000112)1.72371261
64Aplasia/Hypoplasia of the lens (HP:0008063)1.71462801
65Aplasia/Hypoplasia of the spleen (HP:0010451)1.71053323
66Abnormal drinking behavior (HP:0030082)1.70322232
67Polydipsia (HP:0001959)1.70322232
68Abnormality of the renal cortex (HP:0011035)1.65993862
69Oculomotor apraxia (HP:0000657)1.59463554
70Preaxial hand polydactyly (HP:0001177)1.56054573
71Male pseudohermaphroditism (HP:0000037)1.54593686
72Atelectasis (HP:0100750)1.54537250
73Supernumerary spleens (HP:0009799)1.52558261
74Abnormality of renal excretion (HP:0011036)1.51785800
75Hyperinsulinemic hypoglycemia (HP:0000825)1.51355739
76Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.48340541
77Fibular hypoplasia (HP:0003038)1.47015960
78Retinal dysplasia (HP:0007973)1.46123570
79Hyperactive renin-angiotensin system (HP:0000841)1.43908227
80Hypoglycemic seizures (HP:0002173)1.38327752
81Sclerocornea (HP:0000647)1.38128489
82Hyperaldosteronism (HP:0000859)1.37591219
83Anencephaly (HP:0002323)1.37345137
84Broad distal phalanx of finger (HP:0009836)1.36758926
85Chronic hepatic failure (HP:0100626)1.35232872
86Furrowed tongue (HP:0000221)1.34570093
87Abnormal spermatogenesis (HP:0008669)1.32382354
88Missing ribs (HP:0000921)1.31025072
89Abnormal urine output (HP:0012590)1.30452885
90Hyperkalemia (HP:0002153)1.29965504
91Abnormality of macular pigmentation (HP:0008002)1.27054675
92Retinitis pigmentosa (HP:0000510)1.25270104
93Polyuria (HP:0000103)1.24500653
94Broad foot (HP:0001769)1.22737807
95Decreased circulating renin level (HP:0003351)1.22697072
96Abnormality of renin-angiotensin system (HP:0000847)1.20836413
97Hypoglycemic coma (HP:0001325)1.19520312
98Short thorax (HP:0010306)1.18991101
99Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.17806776
100Abnormality of the frontal sinuses (HP:0002687)1.17288360
101Hypokalemic alkalosis (HP:0001949)1.15966371
102Renal salt wasting (HP:0000127)1.15895858
103Bony spicule pigmentary retinopathy (HP:0007737)1.14191449
104Late onset (HP:0003584)1.13567811
105Hypothermia (HP:0002045)1.11832766
106Bifid scrotum (HP:0000048)1.11487391
107Abnormality of chloride homeostasis (HP:0011422)1.09585842
108Gout (HP:0001997)1.09481996
109Cone-rod dystrophy (HP:0000548)1.09259956
110Decreased central vision (HP:0007663)1.08994883
111Symptomatic seizures (HP:0011145)1.08128644
112Constricted visual fields (HP:0001133)1.07966527
113Narrow forehead (HP:0000341)1.05816325
114Xerostomia (HP:0000217)1.05746940
115Absent rod-and cone-mediated responses on ERG (HP:0007688)1.05181886
116Polycystic ovaries (HP:0000147)1.04974167
117Hypodontia (HP:0000668)1.03852871
118Prominent nasal bridge (HP:0000426)0.97464594
119Abnormality of the distal phalanges of the toes (HP:0010182)0.95975001
120Short femoral neck (HP:0100864)0.95899737
121Hyponatremia (HP:0002902)0.94854124
122Hip dysplasia (HP:0001385)0.93850835
123Fetal akinesia sequence (HP:0001989)0.93750501
124Aganglionic megacolon (HP:0002251)0.92914057
125Hand muscle atrophy (HP:0009130)0.92814803

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK157.61577060
2PDK34.64194880
3PDK44.64194880
4PRKD34.04687857
5TESK13.94766335
6PDK23.78420526
7STK162.99234728
8WNK42.25935548
9PIM22.03331366
10PNCK1.89965873
11IRAK11.87030886
12ICK1.85451440
13PIK3CG1.79260366
14NME11.75727345
15MST41.72815511
16ARAF1.72803335
17DYRK1B1.71654839
18IRAK21.59117793
19GRK11.57905948
20PASK1.54572041
21MAP3K21.48156192
22MUSK1.44766496
23HIPK21.43384315
24DYRK31.42533880
25ADRBK21.42533219
26EPHA31.36601299
27TSSK61.33413050
28PTK2B1.33129580
29TTK1.27485024
30EPHB11.20860910
31INSRR1.20327677
32VRK11.17413045
33SMG11.13473735
34LMTK21.10911972
35MAP2K21.09038160
36MAP3K121.05831618
37STK241.00541624
38BRSK20.97919142
39ERBB30.96858929
40EEF2K0.96371695
41MARK20.93277610
42ERBB20.92285444
43CDK30.84346107
44MAP3K40.83797602
45BMPR1B0.82101051
46CAMKK20.79244714
47PHKG20.76960093
48PHKG10.76960093
49STK38L0.76597969
50STK390.72205860
51MAP3K70.71701490
52RPS6KA20.71511971
53TEC0.69727612
54BRAF0.69386680
55NTRK20.67067438
56NLK0.64561229
57WEE10.64051628
58MST1R0.62454429
59MAP2K70.57478274
60TLK10.55235220
61WNK30.55059982
62PRKCG0.54262642
63PAK20.53742276
64MAP2K40.53434102
65TRIB30.53398879
66NEK60.51074774
67MAPKAPK50.47908340
68PTK60.47695258
69TRPM70.47298174
70ITK0.46051540
71TIE10.45897523
72MAPKAPK20.45014677
73KIT0.44470961
74PINK10.44220858
75NEK20.44040953
76DYRK1A0.42494820
77RIPK40.42372661
78SCYL20.41535643
79PRKCQ0.40646249
80FRK0.40447252
81STK100.40345835
82TNIK0.39570858
83OXSR10.37590690
84SGK10.37545764
85ERN10.36934108
86GRK70.35893472
87BCR0.35805260
88MAP3K30.35140620
89MAPK130.34723105
90PDK10.34018305
91EPHB20.33765798
92MYLK0.33662692
93PTK20.33651284
94FLT30.33531404
95EPHA40.33408904
96CCNB10.32957361
97FER0.32413202
98SGK2230.32364384
99SGK4940.32364384
100PBK0.31608255
101GSK3A0.31489278
102TGFBR20.31476664
103MAPK70.30921816
104GRK60.29540789
105ZAP700.28173494
106PRKAA20.27994577
107PRKCE0.27801359
108AURKA0.27687885
109ROCK20.27427547
110MAPKAPK30.27307728
111TBK10.27306226
112MAP4K10.27164593
113BRSK10.26874379
114CAMK1G0.26223481
115EPHA20.26161822
116CDK190.25788693
117LRRK20.25462132
118AKT20.24662046
119PRKG20.24541462
120CAMK2G0.24007005
121BTK0.23767247
122CAMK2A0.23729220
123RPS6KC10.23639507
124RPS6KL10.23639507
125PRKD20.23479053
126PRKCI0.22172537
127PRKCZ0.21567394
128STK380.21468893
129CAMK2D0.21368072
130GRK50.21229654
131MET0.20636409
132PRKCA0.20559511
133FGFR30.20319823
134PRKACA0.20198857
135CAMKK10.20018391
136ABL10.19614612
137PRKACG0.19411376
138CSK0.19134253
139ADRBK10.18543663
140NEK90.18324579
141PDPK10.18109400
142PLK10.18020424
143PRKCD0.17805678
144FYN0.17641056
145ROCK10.17396520
146DYRK20.17239427
147SRC0.17087048
148TAOK10.16175655
149CASK0.15533250

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049505.17841463
2Protein export_Homo sapiens_hsa030603.27033558
3beta-Alanine metabolism_Homo sapiens_hsa004102.93314001
4Huntingtons disease_Homo sapiens_hsa050162.79309455
5Caffeine metabolism_Homo sapiens_hsa002322.72658153
6Sulfur metabolism_Homo sapiens_hsa009202.71089314
7Olfactory transduction_Homo sapiens_hsa047402.65528616
8Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.34249374
9Glycosaminoglycan degradation_Homo sapiens_hsa005312.31910519
10Selenocompound metabolism_Homo sapiens_hsa004502.25573541
11Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.19660516
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.14302062
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.12019723
14Insulin secretion_Homo sapiens_hsa049111.93457169
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.88645119
16Vitamin B6 metabolism_Homo sapiens_hsa007501.76627993
17Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.74960382
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.73782457
19Linoleic acid metabolism_Homo sapiens_hsa005911.72309847
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.69016985
21Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.58576768
22N-Glycan biosynthesis_Homo sapiens_hsa005101.57681542
23Other glycan degradation_Homo sapiens_hsa005111.57529000
24Propanoate metabolism_Homo sapiens_hsa006401.56051867
25Glutathione metabolism_Homo sapiens_hsa004801.55652236
26Glucagon signaling pathway_Homo sapiens_hsa049221.54439588
27Pyruvate metabolism_Homo sapiens_hsa006201.54323633
28Oxidative phosphorylation_Homo sapiens_hsa001901.47736955
29Tight junction_Homo sapiens_hsa045301.45644471
30Chemical carcinogenesis_Homo sapiens_hsa052041.45551862
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.45253357
32Carbohydrate digestion and absorption_Homo sapiens_hsa049731.43467662
33Histidine metabolism_Homo sapiens_hsa003401.43221603
34Purine metabolism_Homo sapiens_hsa002301.42773072
35Arachidonic acid metabolism_Homo sapiens_hsa005901.40066434
36Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.33981679
37Taste transduction_Homo sapiens_hsa047421.25724588
38Basal transcription factors_Homo sapiens_hsa030221.25341111
39Parkinsons disease_Homo sapiens_hsa050121.20326316
40Notch signaling pathway_Homo sapiens_hsa043301.20251286
41Pyrimidine metabolism_Homo sapiens_hsa002401.19936906
42Thyroid hormone synthesis_Homo sapiens_hsa049181.19497400
43Pentose and glucuronate interconversions_Homo sapiens_hsa000401.17996385
44Amphetamine addiction_Homo sapiens_hsa050311.17166315
45ABC transporters_Homo sapiens_hsa020101.15767142
46Basal cell carcinoma_Homo sapiens_hsa052171.10298427
47Glycerophospholipid metabolism_Homo sapiens_hsa005641.10111799
48Vibrio cholerae infection_Homo sapiens_hsa051101.08811963
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.07902016
50Hedgehog signaling pathway_Homo sapiens_hsa043401.07484275
51Ether lipid metabolism_Homo sapiens_hsa005651.07060891
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.03761090
53PPAR signaling pathway_Homo sapiens_hsa033201.01638907
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.99725143
55Alzheimers disease_Homo sapiens_hsa050100.98460441
56Lysosome_Homo sapiens_hsa041420.98221123
57Antigen processing and presentation_Homo sapiens_hsa046120.96028717
58Mineral absorption_Homo sapiens_hsa049780.92782500
59Circadian rhythm_Homo sapiens_hsa047100.91848328
60Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.90153866
61Cocaine addiction_Homo sapiens_hsa050300.89377844
62Retinol metabolism_Homo sapiens_hsa008300.88335482
63Collecting duct acid secretion_Homo sapiens_hsa049660.87910074
64Fructose and mannose metabolism_Homo sapiens_hsa000510.86202127
65Fatty acid biosynthesis_Homo sapiens_hsa000610.84974006
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.83500977
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.82791314
68Nicotine addiction_Homo sapiens_hsa050330.80085004
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79882762
70Fatty acid degradation_Homo sapiens_hsa000710.79673303
71SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78076172
72Galactose metabolism_Homo sapiens_hsa000520.75020517
73Peroxisome_Homo sapiens_hsa041460.71995260
74Metabolic pathways_Homo sapiens_hsa011000.70815434
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.67821643
76Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67071211
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65007699
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.64652241
79Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.61783149
80Ovarian steroidogenesis_Homo sapiens_hsa049130.61377821
81Renin secretion_Homo sapiens_hsa049240.61069671
82Starch and sucrose metabolism_Homo sapiens_hsa005000.60884329
83Phototransduction_Homo sapiens_hsa047440.59967916
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.59868469
85Pentose phosphate pathway_Homo sapiens_hsa000300.59503612
86Dorso-ventral axis formation_Homo sapiens_hsa043200.57018619
87Hippo signaling pathway_Homo sapiens_hsa043900.56897488
88Cardiac muscle contraction_Homo sapiens_hsa042600.55700250
89Choline metabolism in cancer_Homo sapiens_hsa052310.55216332
90Type I diabetes mellitus_Homo sapiens_hsa049400.55187303
91Glycerolipid metabolism_Homo sapiens_hsa005610.54818602
92Tyrosine metabolism_Homo sapiens_hsa003500.54618489
93Adherens junction_Homo sapiens_hsa045200.54182793
94Axon guidance_Homo sapiens_hsa043600.52563637
95Estrogen signaling pathway_Homo sapiens_hsa049150.50552729
96Butanoate metabolism_Homo sapiens_hsa006500.49840591
97Phenylalanine metabolism_Homo sapiens_hsa003600.48588249
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48198291
99Leukocyte transendothelial migration_Homo sapiens_hsa046700.47913714
100Tryptophan metabolism_Homo sapiens_hsa003800.47602684
101cAMP signaling pathway_Homo sapiens_hsa040240.46261151
102Sphingolipid metabolism_Homo sapiens_hsa006000.44441385
103Nitrogen metabolism_Homo sapiens_hsa009100.44090899
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44014763
105Alcoholism_Homo sapiens_hsa050340.43914965
106Melanogenesis_Homo sapiens_hsa049160.43910579
107Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.43234473
108Steroid biosynthesis_Homo sapiens_hsa001000.43127129
109Arginine and proline metabolism_Homo sapiens_hsa003300.40864404
110Aldosterone synthesis and secretion_Homo sapiens_hsa049250.40733711
111Proteasome_Homo sapiens_hsa030500.40452855
112Vitamin digestion and absorption_Homo sapiens_hsa049770.39298165
113Complement and coagulation cascades_Homo sapiens_hsa046100.37782033
114Prion diseases_Homo sapiens_hsa050200.37404820
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37052579
116cGMP-PKG signaling pathway_Homo sapiens_hsa040220.36504932
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35558537
118Pancreatic secretion_Homo sapiens_hsa049720.35279943
119Hepatitis C_Homo sapiens_hsa051600.33252068
120Bile secretion_Homo sapiens_hsa049760.32970306
121Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32820437
122Gastric acid secretion_Homo sapiens_hsa049710.32640056
123Circadian entrainment_Homo sapiens_hsa047130.32366838
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.31384356
125Vascular smooth muscle contraction_Homo sapiens_hsa042700.31062390
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30258060
127Serotonergic synapse_Homo sapiens_hsa047260.29331859
128Nucleotide excision repair_Homo sapiens_hsa034200.28449326
129Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.28149449
130Salivary secretion_Homo sapiens_hsa049700.27864469
131Folate biosynthesis_Homo sapiens_hsa007900.26184524
132Adipocytokine signaling pathway_Homo sapiens_hsa049200.25899843
133Calcium signaling pathway_Homo sapiens_hsa040200.25733756
134Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.23459915
135Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.23319698
136Wnt signaling pathway_Homo sapiens_hsa043100.22201176
137Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20801174
138Amoebiasis_Homo sapiens_hsa051460.20576065
139Glutamatergic synapse_Homo sapiens_hsa047240.18936011
140Dilated cardiomyopathy_Homo sapiens_hsa054140.15320758
141Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.13980351
142Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.13102469
143TGF-beta signaling pathway_Homo sapiens_hsa043500.11358724
144Regulation of autophagy_Homo sapiens_hsa041400.09521611
145Synaptic vesicle cycle_Homo sapiens_hsa047210.08631923

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