CEP170B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.48758377
2synaptic vesicle maturation (GO:0016188)5.48302976
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.06112262
4locomotory exploration behavior (GO:0035641)4.88873427
5synaptic vesicle docking involved in exocytosis (GO:0016081)4.67857918
6glutamate secretion (GO:0014047)4.63696733
7layer formation in cerebral cortex (GO:0021819)4.51754162
8vocalization behavior (GO:0071625)4.42637773
9synaptic vesicle exocytosis (GO:0016079)4.29517105
10regulation of synaptic vesicle exocytosis (GO:2000300)4.22817634
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.21698229
12activation of Rac GTPase activity (GO:0032863)4.04610606
13cell-substrate junction assembly (GO:0007044)3.96000617
14semaphorin-plexin signaling pathway (GO:0071526)3.94278447
15neurotransmitter secretion (GO:0007269)3.90468012
16sodium ion export (GO:0071436)3.86664344
17cytoskeletal anchoring at plasma membrane (GO:0007016)3.77924831
18adherens junction assembly (GO:0034333)3.73549482
19regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.71259556
20proline transport (GO:0015824)3.68231236
21exploration behavior (GO:0035640)3.66376104
22epithelial cell-cell adhesion (GO:0090136)3.65945370
23regulation of synaptic vesicle transport (GO:1902803)3.64263972
24planar cell polarity pathway involved in neural tube closure (GO:0090179)3.63899463
25regulation of glutamate receptor signaling pathway (GO:1900449)3.62208723
26cellular potassium ion homeostasis (GO:0030007)3.62190954
27dendritic spine morphogenesis (GO:0060997)3.62062576
28focal adhesion assembly (GO:0048041)3.54054750
29cell-substrate adherens junction assembly (GO:0007045)3.54054750
30regulation of neuronal synaptic plasticity (GO:0048168)3.50582719
31protein localization to endosome (GO:0036010)3.41570342
32activation of protein kinase A activity (GO:0034199)3.38633775
33regulation of clathrin-mediated endocytosis (GO:2000369)3.38266045
34cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.37313291
35regulation of long-term neuronal synaptic plasticity (GO:0048169)3.37210407
36COPI coating of Golgi vesicle (GO:0048205)3.37050126
37Golgi transport vesicle coating (GO:0048200)3.37050126
38protein retention in ER lumen (GO:0006621)3.33125826
39regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.27761222
40regulation of water loss via skin (GO:0033561)3.27734858
41bundle of His cell to Purkinje myocyte communication (GO:0086069)3.25166781
42protein localization to synapse (GO:0035418)3.21197691
43gamma-aminobutyric acid transport (GO:0015812)3.18955567
44cell communication by electrical coupling (GO:0010644)3.18355075
45cerebellar Purkinje cell layer development (GO:0021680)3.17900256
46maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.17320364
47neuromuscular process controlling balance (GO:0050885)3.11374405
48positive regulation of synapse maturation (GO:0090129)3.11042596
49regulation of early endosome to late endosome transport (GO:2000641)3.08705014
50negative regulation of cell size (GO:0045792)3.08664839
51regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.06612040
52retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.03795941
53dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.03095990
54establishment of apical/basal cell polarity (GO:0035089)3.02355082
55regulation of synapse structural plasticity (GO:0051823)3.01677180
56neurotransmitter transport (GO:0006836)3.00691543
57cerebellar Purkinje cell differentiation (GO:0021702)2.99813237
58ionotropic glutamate receptor signaling pathway (GO:0035235)2.99795316
59negative regulation of fatty acid transport (GO:2000192)2.98816348
60dendrite morphogenesis (GO:0048813)2.95880793
61regulation of ARF protein signal transduction (GO:0032012)2.95417655
62neuromuscular process controlling posture (GO:0050884)2.95393477
63cell communication involved in cardiac conduction (GO:0086065)2.93780327
64atrioventricular valve morphogenesis (GO:0003181)2.92185919
65establishment of skin barrier (GO:0061436)2.92038943
66negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.91753606
67peptidyl-tyrosine autophosphorylation (GO:0038083)2.88055687
68endothelial cell chemotaxis (GO:0035767)2.87162227
69chemosensory behavior (GO:0007635)2.85063690
70synaptic vesicle endocytosis (GO:0048488)2.84418515
71vesicle transport along microtubule (GO:0047496)2.83961616
72glycine transport (GO:0015816)2.83623093
73synaptic transmission, glutamatergic (GO:0035249)2.80659813
74dendritic spine organization (GO:0097061)2.80129104
75apoptotic process involved in morphogenesis (GO:0060561)2.79080903
76regulation of neurotransmitter levels (GO:0001505)2.76539809
77regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.76498185
78neuronal action potential propagation (GO:0019227)2.75405126
79branching involved in mammary gland duct morphogenesis (GO:0060444)2.75109714
80regulation of glucose import in response to insulin stimulus (GO:2001273)2.74320697
81multicellular organismal water homeostasis (GO:0050891)2.74136046
82long-term memory (GO:0007616)2.73928216
83negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.73660124
84alanine transport (GO:0032328)2.72321443
85neuron cell-cell adhesion (GO:0007158)2.71430094
86insulin-like growth factor receptor signaling pathway (GO:0048009)2.71429605
87regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.70080175
88regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.69700505
89regulation of synaptic plasticity (GO:0048167)2.68407253
90positive regulation of membrane potential (GO:0045838)2.67423211
91lung epithelium development (GO:0060428)2.66880788
92membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.64942611
93cell migration in hindbrain (GO:0021535)2.64104087
94positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.63422906
95regulation of mammary gland epithelial cell proliferation (GO:0033599)2.62428761
96regulation of cholesterol biosynthetic process (GO:0045540)2.62244357
97regulation of cholesterol homeostasis (GO:2000188)2.61955051
98positive regulation of vesicle fusion (GO:0031340)2.61595419
99regulation of fatty acid beta-oxidation (GO:0031998)2.60798414
100neurotransmitter-gated ion channel clustering (GO:0072578)2.60061929
101innervation (GO:0060384)2.58338624
102axonal fasciculation (GO:0007413)2.58206671
103regulation of vesicle fusion (GO:0031338)2.57955071
104neuron-neuron synaptic transmission (GO:0007270)2.57711422
105neuron recognition (GO:0008038)2.57448955
106organelle transport along microtubule (GO:0072384)2.57327394
107regulation of calcium ion-dependent exocytosis (GO:0017158)2.57235753
108regulation of dendritic spine morphogenesis (GO:0061001)2.56370609
109cellular sodium ion homeostasis (GO:0006883)2.55872574
110glutamate receptor signaling pathway (GO:0007215)2.55616382
111desmosome organization (GO:0002934)2.55100478
112regulation of neurotransmitter secretion (GO:0046928)2.54416725
113cell volume homeostasis (GO:0006884)2.54030261
114positive regulation of Cdc42 GTPase activity (GO:0043089)2.53987204
115cell junction maintenance (GO:0034331)2.53857934
116cerebellar granule cell differentiation (GO:0021707)2.52983379
117myelin maintenance (GO:0043217)2.52895315
118skin morphogenesis (GO:0043589)2.52350704
119regulation of excitatory postsynaptic membrane potential (GO:0060079)2.51758392
120membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.50219396
121potassium ion homeostasis (GO:0055075)2.50114613
122establishment of nucleus localization (GO:0040023)2.49031698
123regulation of postsynaptic membrane potential (GO:0060078)2.48961863
124actin filament bundle organization (GO:0061572)2.47858241
125actin filament bundle assembly (GO:0051017)2.47858241
126apical protein localization (GO:0045176)2.47278083
127social behavior (GO:0035176)2.47107100
128intraspecies interaction between organisms (GO:0051703)2.47107100
129endocytic recycling (GO:0032456)2.46533280
130neuronal ion channel clustering (GO:0045161)2.46207517
131neuromuscular process (GO:0050905)2.45401568
132basement membrane organization (GO:0071711)2.45265974
133regulation of cardioblast differentiation (GO:0051890)2.44727985
134Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.43950395
135G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.43326312
136mating behavior (GO:0007617)2.43045690
137axon cargo transport (GO:0008088)2.41983532
138negative regulation of catenin import into nucleus (GO:0035414)2.41917877
139auditory behavior (GO:0031223)2.41717282
140protein targeting to plasma membrane (GO:0072661)2.41498627
141membrane repolarization (GO:0086009)2.41474439
142vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.40897376
143adherens junction organization (GO:0034332)2.40471244
144proline biosynthetic process (GO:0006561)2.40340510
145hemidesmosome assembly (GO:0031581)2.40317880
146positive regulation of synaptic transmission, GABAergic (GO:0032230)2.40299730
147suckling behavior (GO:0001967)2.39249186
148membrane repolarization during action potential (GO:0086011)2.38938023
149maternal placenta development (GO:0001893)2.38850394
150synapse organization (GO:0050808)2.38491496
151establishment of monopolar cell polarity (GO:0061162)2.37951529
152establishment or maintenance of monopolar cell polarity (GO:0061339)2.37951529
153amino acid import (GO:0043090)2.37809802
154potassium ion import (GO:0010107)2.37375818
155positive regulation of establishment of protein localization to plasma membrane (GO:0090004)2.36507060
156asymmetric protein localization (GO:0008105)2.36360200
157signal release (GO:0023061)2.35756051
158positive regulation of receptor recycling (GO:0001921)2.35525627
159cell junction assembly (GO:0034329)2.35117884
160prepulse inhibition (GO:0060134)2.34976168
161branching involved in salivary gland morphogenesis (GO:0060445)2.34387323
162response to auditory stimulus (GO:0010996)2.34238532
163regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.34074292
164regulation of ARF GTPase activity (GO:0032312)2.33380637
165cell-cell junction maintenance (GO:0045217)2.33348017
166plasma membrane repair (GO:0001778)2.32827826
167negative regulation of hormone metabolic process (GO:0032351)2.31818490
168barbed-end actin filament capping (GO:0051016)2.31169247
169dopamine receptor signaling pathway (GO:0007212)2.29450570
170actin filament depolymerization (GO:0030042)2.28609632
171gap junction assembly (GO:0016264)2.27498982
172regulation of establishment of planar polarity (GO:0090175)2.27168382
173regulation of synapse maturation (GO:0090128)2.26993240
174positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.26736675
175receptor catabolic process (GO:0032801)2.25825419
176regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.25446405
177establishment or maintenance of bipolar cell polarity (GO:0061245)2.25018123
178establishment or maintenance of apical/basal cell polarity (GO:0035088)2.25018123
179positive regulation of protein localization to plasma membrane (GO:1903078)2.24122786

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.81660359
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.55222676
3TP63_17297297_ChIP-ChIP_HaCaT_Human2.81655811
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.52184641
5DROSHA_22980978_ChIP-Seq_HELA_Human2.33992552
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.28819066
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.21887348
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.17303153
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.17303153
10ELK3_25401928_ChIP-Seq_HUVEC_Human2.15162994
11RARB_27405468_Chip-Seq_BRAIN_Mouse2.14923831
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.10871167
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.09830754
14JARID2_20064375_ChIP-Seq_MESCs_Mouse2.08726883
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.04920885
16TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.00481585
17REST_21632747_ChIP-Seq_MESCs_Mouse1.94866929
18ERG_21242973_ChIP-ChIP_JURKAT_Human1.94098644
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90715758
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.87446700
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.82665592
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.82609368
23UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.82410068
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.81782227
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.81352855
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.80478424
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.79754645
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.78621060
29ZFP281_18757296_ChIP-ChIP_E14_Mouse1.77367660
30SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.76896587
31KDM2B_26808549_Chip-Seq_K562_Human1.76775867
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.76620465
33KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.66807970
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.64989274
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64165504
36KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.63491050
37ESR2_21235772_ChIP-Seq_MCF-7_Human1.60871957
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.60273713
39GBX2_23144817_ChIP-Seq_PC3_Human1.58243167
40ZNF217_24962896_ChIP-Seq_MCF-7_Human1.58050149
41EED_16625203_ChIP-ChIP_MESCs_Mouse1.56811828
42WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.56078200
43PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.56040860
44PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.55326447
45TCF7_22412390_ChIP-Seq_EML_Mouse1.53877092
46TET1_21451524_ChIP-Seq_MESCs_Mouse1.52611321
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.51141032
48P68_20966046_ChIP-Seq_HELA_Human1.51133002
49SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50800623
50IKZF1_21737484_ChIP-ChIP_HCT116_Human1.49453703
51RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.48050111
52SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.45732452
53EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.43839482
54DNAJC2_21179169_ChIP-ChIP_NT2_Human1.41787868
55TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.41214274
56ZFP281_27345836_Chip-Seq_ESCs_Mouse1.39961135
57CLOCK_20551151_ChIP-Seq_293T_Human1.36863588
58GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.35732794
59ATF3_27146783_Chip-Seq_COLON_Human1.34766773
60ZNF263_19887448_ChIP-Seq_K562_Human1.34019856
61KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33928629
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33094511
63P63_26484246_Chip-Seq_KERATINOCYTES_Human1.32936952
64SRY_22984422_ChIP-ChIP_TESTIS_Rat1.32670677
65WT1_25993318_ChIP-Seq_PODOCYTE_Human1.32141000
66SA1_27219007_Chip-Seq_ERYTHROID_Human1.32047870
67TP53_22127205_ChIP-Seq_IMR90_Human1.29879515
68SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.29872731
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.26170161
70VDR_21846776_ChIP-Seq_THP-1_Human1.24306596
71AHR_22903824_ChIP-Seq_MCF-7_Human1.24104340
72RING1B_27294783_Chip-Seq_ESCs_Mouse1.23092756
73TP63_22573176_ChIP-Seq_HFKS_Human1.22367755
74SOX2_27498859_Chip-Seq_STOMACH_Mouse1.22303979
75AR_21572438_ChIP-Seq_LNCaP_Human1.22049607
76TRIM28_21343339_ChIP-Seq_HEK293_Human1.21946302
77KDM2B_26808549_Chip-Seq_SUP-B15_Human1.21238074
78NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.21143612
79LXR_22292898_ChIP-Seq_THP-1_Human1.20885666
80RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.20651327
81CDX2_20551321_ChIP-Seq_CACO-2_Human1.19544574
82ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.17081006
83DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17064502
84AR_19668381_ChIP-Seq_PC3_Human1.16449837
85NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.15503525
86RING1B_27294783_Chip-Seq_NPCs_Mouse1.13783532
87ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.13471492
88HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11341903
89TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10949994
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.10249079
91TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09889894
92ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.09275388
93SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.09048908
94ZNF274_21170338_ChIP-Seq_K562_Hela1.09044652
95CTCF_27219007_Chip-Seq_Bcells_Human1.07348011
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06419148
97TET1_21490601_ChIP-Seq_MESCs_Mouse1.05757218
98UBF1/2_26484160_Chip-Seq_HMECs_Human1.05720593
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.05644131
100ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.05388148
101ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.04970028
102CREB1_26743006_Chip-Seq_LNCaP_Human1.04713621
103ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03932934
104ESR1_21235772_ChIP-Seq_MCF-7_Human1.03394558
105TP53_23651856_ChIP-Seq_MEFs_Mouse1.01553703
106RXR_22108803_ChIP-Seq_LS180_Human1.01469323
107ESR1_20079471_ChIP-ChIP_T-47D_Human1.01464962
108CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01050544
109NR3C1_23031785_ChIP-Seq_PC12_Mouse1.00972150
110NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99661026
111RACK7_27058665_Chip-Seq_MCF-7_Human0.99262330
112SMAD3_21741376_ChIP-Seq_HESCs_Human0.98773314
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.98355666
114ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98166006
115KDM2B_26808549_Chip-Seq_DND41_Human0.97874748
116TP53_20018659_ChIP-ChIP_R1E_Mouse0.97637515
117SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.97355166
118CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97303584
119SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.97289357
120RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97207372
121NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97187222
122SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.97097670
123P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96920161
124SMAD4_21799915_ChIP-Seq_A2780_Human0.96794044
125MYC_22102868_ChIP-Seq_BL_Human0.96730627
126KDM2B_26808549_Chip-Seq_JURKAT_Human0.96507980
127DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96466252
128RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.95484102
129MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.94841090
130SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.94792422
131SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.94792422
132YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94770434
133PPARA_22158963_ChIP-Seq_LIVER_Mouse0.94712310
134RUNX1_27514584_Chip-Seq_MCF-7_Human0.94620279
135CTBP2_25329375_ChIP-Seq_LNCAP_Human0.94285242
136TP53_16413492_ChIP-PET_HCT116_Human0.93905349
137SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93407273
138CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92996365
139SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.91511942
140ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.90247821
141SMC4_20622854_ChIP-Seq_HELA_Human0.88785558
142KLF5_25053715_ChIP-Seq_YYC3_Human0.88475853
143SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87307564
144FOXA2_19822575_ChIP-Seq_HepG2_Human0.87265202
145EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.87077174
146SMAD3_21741376_ChIP-Seq_ESCs_Human0.86058297
147OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.85740319
148THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.85679768

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.69593951
2MP0010234_abnormal_vibrissa_follicle3.51484929
3MP0004270_analgesia3.45462144
4MP0003635_abnormal_synaptic_transmissio3.28501215
5MP0009780_abnormal_chondrocyte_physiolo2.96190538
6MP0000566_synostosis2.81708325
7MP0005409_darkened_coat_color2.77836952
8MP0004858_abnormal_nervous_system2.61212978
9MP0003283_abnormal_digestive_organ2.57889220
10MP0002063_abnormal_learning/memory/cond2.51325043
11MP0002909_abnormal_adrenal_gland2.36798069
12MP0003880_abnormal_central_pattern2.27943170
13MP0009745_abnormal_behavioral_response2.26538524
14MP0002249_abnormal_larynx_morphology2.26141810
15MP0009046_muscle_twitch2.20883637
16MP0003453_abnormal_keratinocyte_physiol2.20143919
17MP0003705_abnormal_hypodermis_morpholog2.16401747
18MP0002064_seizures2.14211042
19MP0002734_abnormal_mechanical_nocicepti2.06422551
20MP0008438_abnormal_cutaneous_collagen2.05662655
21MP0003329_amyloid_beta_deposits2.01981611
22MP0002572_abnormal_emotion/affect_behav1.98794104
23MP0005257_abnormal_intraocular_pressure1.86807145
24MP0004272_abnormal_basement_membrane1.84655350
25MP0005423_abnormal_somatic_nervous1.83116112
26MP0002060_abnormal_skin_morphology1.82719567
27MP0002098_abnormal_vibrissa_morphology1.79848075
28MP0001968_abnormal_touch/_nociception1.78079402
29MP0010030_abnormal_orbit_morphology1.76665976
30MP0002822_catalepsy1.74539058
31MP0002796_impaired_skin_barrier1.70646416
32MP0000762_abnormal_tongue_morphology1.67222228
33MP0008961_abnormal_basal_metabolism1.67174596
34MP0003879_abnormal_hair_cell1.64489794
35MP0002733_abnormal_thermal_nociception1.63580202
36MP0001501_abnormal_sleep_pattern1.63011501
37MP0000013_abnormal_adipose_tissue1.62574977
38MP0001486_abnormal_startle_reflex1.57669364
39MP0004885_abnormal_endolymph1.56185992
40MP0004811_abnormal_neuron_physiology1.54130420
41MP0002272_abnormal_nervous_system1.51865630
42MP0001440_abnormal_grooming_behavior1.48365918
43MP0005623_abnormal_meninges_morphology1.44042849
44MP0002184_abnormal_innervation1.38141984
45MP0008569_lethality_at_weaning1.38110472
46MP0005023_abnormal_wound_healing1.37730904
47MP0003122_maternal_imprinting1.35092951
48MP0000579_abnormal_nail_morphology1.34752555
49MP0010678_abnormal_skin_adnexa1.34179447
50MP0001970_abnormal_pain_threshold1.33403388
51MP0000955_abnormal_spinal_cord1.32262385
52MP0001216_abnormal_epidermal_layer1.31854920
53MP0005058_abnormal_lysosome_morphology1.30612907
54MP0002234_abnormal_pharynx_morphology1.30354896
55MP0000537_abnormal_urethra_morphology1.30237636
56MP0002557_abnormal_social/conspecific_i1.29204562
57MP0003045_fibrosis1.27188250
58MP0000569_abnormal_digit_pigmentation1.25867849
59MP0001958_emphysema1.25760251
60MP0005275_abnormal_skin_tensile1.24903568
61MP0002877_abnormal_melanocyte_morpholog1.24036343
62MP0003091_abnormal_cell_migration1.21829660
63MP0000778_abnormal_nervous_system1.21674806
64MP0005360_urolithiasis1.20170672
65MP0004185_abnormal_adipocyte_glucose1.16570853
66MP0004782_abnormal_surfactant_physiolog1.16570369
67MP0003279_aneurysm1.16145058
68MP0008260_abnormal_autophagy1.13698882
69MP0009840_abnormal_foam_cell1.13067184
70MP0001299_abnormal_eye_distance/1.11884091
71MP0002735_abnormal_chemical_nociception1.11438892
72MP0001849_ear_inflammation1.10902050
73MP0005451_abnormal_body_composition1.06919612
74MP0002067_abnormal_sensory_capabilities1.06591882
75MP0005187_abnormal_penis_morphology1.06494989
76MP0003787_abnormal_imprinting1.05681757
77MP0002882_abnormal_neuron_morphology1.05014202
78MP0005670_abnormal_white_adipose1.04222016
79MP0000534_abnormal_ureter_morphology1.02160909
80MP0000733_abnormal_muscle_development1.01824256
81MP0005375_adipose_tissue_phenotype1.01575792
82MP0002736_abnormal_nociception_after1.00655369
83MP0000377_abnormal_hair_follicle0.99739937
84MP0005386_behavior/neurological_phenoty0.99414239
85MP0004924_abnormal_behavior0.99414239
86MP0004233_abnormal_muscle_weight0.99303049
87MP0001177_atelectasis0.98674988
88MP0002066_abnormal_motor_capabilities/c0.97858219
89MP0005666_abnormal_adipose_tissue0.97685478
90MP0002896_abnormal_bone_mineralization0.95682868
91MP0005076_abnormal_cell_differentiation0.95542985
92MP0009384_cardiac_valve_regurgitation0.95077431
93MP0003633_abnormal_nervous_system0.93417307
94MP0003119_abnormal_digestive_system0.93279323
95MP0000383_abnormal_hair_follicle0.92401099
96MP0001348_abnormal_lacrimal_gland0.92269137
97MP0000003_abnormal_adipose_tissue0.91983054
98MP0003634_abnormal_glial_cell0.90074747
99MP0002152_abnormal_brain_morphology0.89119565
100MP0003191_abnormal_cellular_cholesterol0.88578078
101MP0004043_abnormal_pH_regulation0.85143117
102MP0005508_abnormal_skeleton_morphology0.84898495
103MP0004264_abnormal_extraembryonic_tissu0.84258521
104MP0003942_abnormal_urinary_system0.83827949
105MP0002069_abnormal_eating/drinking_beha0.82594947
106MP0002089_abnormal_postnatal_growth/wei0.82136735
107MP0005501_abnormal_skin_physiology0.81807961
108MP0000467_abnormal_esophagus_morphology0.81704929
109MP0003631_nervous_system_phenotype0.81097253
110MP0010386_abnormal_urinary_bladder0.80605073
111MP0003566_abnormal_cell_adhesion0.80569247
112MP0005645_abnormal_hypothalamus_physiol0.80280632
113MP0005646_abnormal_pituitary_gland0.80127394
114MP0001664_abnormal_digestion0.80081634
115MP0000604_amyloidosis0.79951757
116MP0003941_abnormal_skin_development0.79107985
117MP0001502_abnormal_circadian_rhythm0.79097818
118MP0006276_abnormal_autonomic_nervous0.77504863
119MP0001984_abnormal_olfaction0.77439309
120MP0003075_altered_response_to0.77028185
121MP0003115_abnormal_respiratory_system0.76739358
122MP0000681_abnormal_thyroid_gland0.76569101
123MP0003632_abnormal_nervous_system0.75826797
124MP0009931_abnormal_skin_appearance0.75773362
125MP0003172_abnormal_lysosome_physiology0.75699995
126MP0000627_abnormal_mammary_gland0.75159898
127MP0000678_abnormal_parathyroid_gland0.74709302
128MP0004947_skin_inflammation0.74588122
129MP0006138_congestive_heart_failure0.74404678
130MP0004381_abnormal_hair_follicle0.73978267
131MP0000751_myopathy0.72775145
132MP0009379_abnormal_foot_pigmentation0.71581023
133MP0005248_abnormal_Harderian_gland0.71114494
134MP0005394_taste/olfaction_phenotype0.70504196
135MP0005499_abnormal_olfactory_system0.70504196
136MP0001346_abnormal_lacrimal_gland0.70101798
137MP0001944_abnormal_pancreas_morphology0.69736305
138MP0010771_integument_phenotype0.69467877
139MP0010352_gastrointestinal_tract_polyps0.69408918
140MP0000462_abnormal_digestive_system0.67535903
141MP0003123_paternal_imprinting0.66807150
142MP0000767_abnormal_smooth_muscle0.66558115
143MP0002116_abnormal_craniofacial_bone0.66397258
144MP0009053_abnormal_anal_canal0.65441406
145MP0002254_reproductive_system_inflammat0.65410535
146MP0008874_decreased_physiological_sensi0.65377383
147MP0008872_abnormal_physiological_respon0.65150394
148MP0002090_abnormal_vision0.64534543
149MP0005503_abnormal_tendon_morphology0.63731012
150MP0000538_abnormal_urinary_bladder0.59951276
151MP0010368_abnormal_lymphatic_system0.59754768
152MP0005621_abnormal_cell_physiology0.56936919
153MP0001765_abnormal_ion_homeostasis0.56799041
154MP0001243_abnormal_dermal_layer0.56112261

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.41230696
2Visual hallucinations (HP:0002367)3.89903390
3Focal motor seizures (HP:0011153)3.83676345
4Focal seizures (HP:0007359)3.65010622
5Broad face (HP:0000283)3.28125060
6Abnormality of the lower motor neuron (HP:0002366)3.22389337
7Protrusio acetabuli (HP:0003179)3.21844798
8Premature rupture of membranes (HP:0001788)3.13266893
9Distal lower limb amyotrophy (HP:0008944)3.08024927
10Action tremor (HP:0002345)2.97131715
11Ankle clonus (HP:0011448)2.96285519
12Supranuclear gaze palsy (HP:0000605)2.90361516
13Thin bony cortex (HP:0002753)2.75666347
14Progressive cerebellar ataxia (HP:0002073)2.74532732
15Pili torti (HP:0003777)2.65445513
16Mildly elevated creatine phosphokinase (HP:0008180)2.63239327
17Ulnar bowing (HP:0003031)2.62843792
18Ventricular fibrillation (HP:0001663)2.62391250
19Flat acetabular roof (HP:0003180)2.61858979
20Cervical subluxation (HP:0003308)2.59884134
21Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.59034386
22Stridor (HP:0010307)2.58562935
23Distal upper limb amyotrophy (HP:0007149)2.52891911
24Upper limb amyotrophy (HP:0009129)2.52891911
25Absence seizures (HP:0002121)2.52778648
26Bronchomalacia (HP:0002780)2.51994719
27Epileptic encephalopathy (HP:0200134)2.49791226
28Genetic anticipation (HP:0003743)2.49472029
29Cerebral inclusion bodies (HP:0100314)2.48665658
30Generalized tonic-clonic seizures (HP:0002069)2.47986619
31Papilledema (HP:0001085)2.46969760
32Atonic seizures (HP:0010819)2.44553065
33Depression (HP:0000716)2.43889024
34Short nail (HP:0001799)2.42853102
35Hand muscle atrophy (HP:0009130)2.42673249
36Spinal cord compression (HP:0002176)2.40669554
37Ankyloglossia (HP:0010296)2.40018328
38Distal lower limb muscle weakness (HP:0009053)2.38691052
39Postural instability (HP:0002172)2.38682436
40Right ventricular cardiomyopathy (HP:0011663)2.36380947
41Insomnia (HP:0100785)2.33981406
42Urinary bladder sphincter dysfunction (HP:0002839)2.33570107
43Advanced eruption of teeth (HP:0006288)2.31880692
44Dysdiadochokinesis (HP:0002075)2.29792749
45Torticollis (HP:0000473)2.27993690
46Increased connective tissue (HP:0009025)2.27158657
47J-shaped sella turcica (HP:0002680)2.24094983
48Abnormality of the distal phalanges of the toes (HP:0010182)2.23104597
49Turricephaly (HP:0000262)2.23102819
50Abnormal social behavior (HP:0012433)2.21712287
51Impaired social interactions (HP:0000735)2.21712287
52Impaired vibration sensation in the lower limbs (HP:0002166)2.21556904
53Dysmetric saccades (HP:0000641)2.21375220
54Atrophic scars (HP:0001075)2.20239532
55Hemiplegia (HP:0002301)2.18123578
56Alopecia of scalp (HP:0002293)2.16132761
57Abnormality of nail color (HP:0100643)2.14625236
58Megalencephaly (HP:0001355)2.13615277
59Poor eye contact (HP:0000817)2.13152802
60Pterygium (HP:0001059)2.13119270
61Macroorchidism (HP:0000053)2.12190923
62Hyperacusis (HP:0010780)2.12034334
63Plantar hyperkeratosis (HP:0007556)2.09573006
64Obstructive sleep apnea (HP:0002870)2.09309088
65Dialeptic seizures (HP:0011146)2.09240635
66Shallow orbits (HP:0000586)2.07732486
67Achilles tendon contracture (HP:0001771)2.05670131
68Bladder diverticulum (HP:0000015)2.05596957
69Axonal loss (HP:0003447)2.05182183
70Spinal rigidity (HP:0003306)2.03374755
71Hypercortisolism (HP:0001578)2.02979138
72Natal tooth (HP:0000695)2.02703329
73Agitation (HP:0000713)2.01889969
74Milia (HP:0001056)2.00329873
75Hyperparathyroidism (HP:0000843)1.99650895
76Intention tremor (HP:0002080)1.99542052
77Febrile seizures (HP:0002373)1.99251832
78Pointed chin (HP:0000307)1.98897223
79Selective tooth agenesis (HP:0001592)1.98697148
80Impaired smooth pursuit (HP:0007772)1.98581944
81Urinary urgency (HP:0000012)1.98491761
82Difficulty climbing stairs (HP:0003551)1.98394844
83Abnormal hair laboratory examination (HP:0003328)1.98095459
84Lower limb amyotrophy (HP:0007210)1.96933992
85Mutism (HP:0002300)1.96552606
86Abnormality of the Achilles tendon (HP:0005109)1.96177312
87Cerebral aneurysm (HP:0004944)1.95895687
88Arterial tortuosity (HP:0005116)1.95869417
89Insidious onset (HP:0003587)1.95647192
90Termporal pattern (HP:0011008)1.95647192
91Abnormality of the distal phalanx of the thumb (HP:0009617)1.95154869
92Focal dystonia (HP:0004373)1.93696387
93Broad metatarsal (HP:0001783)1.93001627
94Neurofibrillary tangles (HP:0002185)1.91662611
95EEG with generalized epileptiform discharges (HP:0011198)1.90478710
96Amblyopia (HP:0000646)1.90183888
97Truncal ataxia (HP:0002078)1.89655157
98Hypoplasia of dental enamel (HP:0006297)1.89481312
99Elfin facies (HP:0004428)1.89269646
100Long palpebral fissure (HP:0000637)1.89041169
101Hypsarrhythmia (HP:0002521)1.87868739
102Acanthosis nigricans (HP:0000956)1.87843011
103Epileptiform EEG discharges (HP:0011182)1.87475649
104Bundle branch block (HP:0011710)1.87307578
105Nail dystrophy (HP:0008404)1.87044846
106Mitral regurgitation (HP:0001653)1.87011005
107Abnormal eating behavior (HP:0100738)1.86258993
108Hypoventilation (HP:0002791)1.85754722
109Vascular tortuosity (HP:0004948)1.85656803
110Dysmetria (HP:0001310)1.83817774
111Onycholysis (HP:0001806)1.83460995
112Resting tremor (HP:0002322)1.83130523
113Anxiety (HP:0000739)1.82860686
114Lymphangioma (HP:0100764)1.81668993
115Intellectual disability, profound (HP:0002187)1.81347902
116Fragile nails (HP:0001808)1.81322158
117Craniofacial dystonia (HP:0012179)1.80000068
118Abnormality of oral frenula (HP:0000190)1.78922767
119Aplasia involving bones of the upper limbs (HP:0009823)1.78874716
120Aplasia of the phalanges of the hand (HP:0009802)1.78874716
121Aplasia involving bones of the extremities (HP:0009825)1.78874716
122Wormian bones (HP:0002645)1.78506014
123Neoplasm of the heart (HP:0100544)1.77474528
124Disproportionate tall stature (HP:0001519)1.76115259
125Nuclear cataract (HP:0100018)1.75880635
126Vertebral compression fractures (HP:0002953)1.74092223
127Thick nail (HP:0001805)1.73569059
128Neonatal death (HP:0003811)1.73325502
129Enlarged penis (HP:0000040)1.73304220
130Drooling (HP:0002307)1.73085263
131Excessive salivation (HP:0003781)1.73085263
132Ankle contracture (HP:0006466)1.73054913
133Status epilepticus (HP:0002133)1.72928041
134Bradykinesia (HP:0002067)1.70828420
135Bowel diverticulosis (HP:0005222)1.70408767
136Spastic gait (HP:0002064)1.69811874
137Atelectasis (HP:0100750)1.69754293
138Aneurysm (HP:0002617)1.68876344
139Abnormality of ocular smooth pursuit (HP:0000617)1.68766401
140Abnormality of carpal bone ossification (HP:0006257)1.68161015
141Hemorrhage of the eye (HP:0011885)1.68157964
142Germ cell neoplasia (HP:0100728)1.68104572
143Overgrowth (HP:0001548)1.67223006
144Rapidly progressive (HP:0003678)1.67172839
145Gaze-evoked nystagmus (HP:0000640)1.65932436
146Neonatal short-limb short stature (HP:0008921)1.65787928
147Abnormal ossification of hand bones (HP:0005921)1.65363855
148Abnormality of the salivary glands (HP:0010286)1.65199280
149Blue sclerae (HP:0000592)1.65184147
150Annular pancreas (HP:0001734)1.64981862
151Clonus (HP:0002169)1.64903285
152Postural tremor (HP:0002174)1.64280979
153Arnold-Chiari malformation (HP:0002308)1.63577785
154Congenital glaucoma (HP:0001087)1.63171530
155Overriding aorta (HP:0002623)1.63124394
156Broad-based gait (HP:0002136)1.63102816
157Fragile skin (HP:0001030)1.62797361
158Scanning speech (HP:0002168)1.62733587
159Buphthalmos (HP:0000557)1.62380419
160Stereotypic behavior (HP:0000733)1.62038335
161Urethral obstruction (HP:0000796)1.61668338
162Premature skin wrinkling (HP:0100678)1.60868338
163Long toe (HP:0010511)1.60397377
164Focal segmental glomerulosclerosis (HP:0000097)1.60226107
165Bowing of the arm (HP:0006488)1.58126083
166Bowed forearm bones (HP:0003956)1.58126083
167Distal sensory impairment (HP:0002936)1.58110836
168Precocious puberty (HP:0000826)1.57566733
169Abnormality of dentin (HP:0010299)1.55775926
170Genu recurvatum (HP:0002816)1.55616962

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.08971252
2NTRK33.33499426
3SMG12.91425042
4PRKD32.83599130
5MARK12.51997284
6EPHA42.47011593
7RIPK12.40659776
8MAP3K42.36826756
9PAK62.33361849
10IRAK32.31245036
11NTRK12.29323470
12LATS22.27342998
13MINK12.17624986
14DAPK22.16274037
15MAP3K22.14905292
16MET2.06232522
17KSR22.03144999
18TRIB31.93282636
19TAOK11.83149680
20CAMKK11.82466442
21STK381.77446541
22NTRK21.64417506
23PRPF4B1.60760429
24MAP2K41.56939657
25TESK11.56933511
26TYRO31.55935124
27EPHA21.50354124
28CDK121.43932216
29FER1.43129518
30DDR21.40351021
31PDGFRA1.38283993
32PAK41.32058421
33PAK31.30014605
34TTN1.26326246
35KSR11.22663611
36FGFR41.22150059
37PTK21.21823319
38CDK51.20959871
39RET1.20723314
40PKN21.17960520
41ALK1.17746039
42LATS11.17460830
43MAP2K71.10504710
44PRKCH0.99456131
45SCYL20.99002135
46ICK0.97910223
47STK110.95589657
48LMTK20.93912498
49DAPK10.93182788
50CAMK1D0.91685262
51SIK20.91554051
52UHMK10.91129469
53BMX0.90508661
54CDC42BPA0.90257433
55GRK50.90214395
56MAP3K10.89519514
57NEK10.86352035
58MAPKAPK30.84566187
59PTK60.84329754
60FRK0.83675080
61PRKG20.83643448
62MARK20.79494103
63NME20.79477667
64EPHB20.77330713
65PRKCG0.77271070
66MAP3K60.76474433
67MAP2K10.73294742
68EEF2K0.72972276
69IRAK20.72782466
70MAP3K110.72714603
71EPHB10.72689956
72MAP3K30.72644233
73MAP3K130.71926300
74MAP3K70.71694384
75SGK30.69691992
76SIK10.68576732
77PLK20.68510412
78DMPK0.66608871
79CAMK1G0.66339808
80CDK150.66038575
81WNK30.65790102
82CDK180.64078917
83NEK60.64029286
84MAP3K120.64025384
85CDK140.63846915
86TAOK20.63679400
87CAMK10.62032388
88PHKG10.60193246
89PHKG20.60193246
90MAPK150.59804367
91ARAF0.59592826
92RPS6KA20.58409084
93MAP3K100.57355145
94ERN10.56444685
95BRAF0.56378274
96CAMK2G0.55680807
97SGK2230.55488555
98SGK4940.55488555
99WNK10.55200733
100CSNK1G20.54725135
101CAMK2A0.54723198
102CDK11A0.54589720
103MTOR0.51367907
104SGK10.50800701
105PRKCZ0.50602372
106CAMKK20.49468146
107PDPK10.48847051
108MST1R0.48295375
109FGFR20.46994017
110FGFR10.46935928
111PIM20.46715376
112RPS6KA30.46100803
113PNCK0.45213105
114ILK0.44816223
115PRKD20.44664289
116ROCK10.44228394
117PAK20.42841578
118INSRR0.42421795
119ERBB20.42071247
120HIPK20.42024241
121MAP2K20.41770025
122CSNK1E0.41064055
123PDGFRB0.40602222
124RPS6KB20.39959532
125SGK20.39633195
126LIMK10.39514159
127WNK40.38792282
128RPS6KC10.38688194
129RPS6KL10.38688194
130PRKCI0.38226212
131DAPK30.38003873
132MAP2K60.37991987
133PDK10.37552893
134MAPK100.36497849
135CAMK2B0.36170658
136ROCK20.32925579
137MUSK0.31649593
138ABL20.31057651
139MAPK80.30648518

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.73261470
2Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.41022980
3Nitrogen metabolism_Homo sapiens_hsa009102.18388345
4Nicotine addiction_Homo sapiens_hsa050332.13705245
5Insulin secretion_Homo sapiens_hsa049112.06791604
6Long-term potentiation_Homo sapiens_hsa047201.98308766
7GABAergic synapse_Homo sapiens_hsa047271.98210123
8Circadian entrainment_Homo sapiens_hsa047131.96100465
9Cyanoamino acid metabolism_Homo sapiens_hsa004601.92525622
10Olfactory transduction_Homo sapiens_hsa047401.88211884
11Notch signaling pathway_Homo sapiens_hsa043301.85664072
12Amphetamine addiction_Homo sapiens_hsa050311.82537531
13Glutamatergic synapse_Homo sapiens_hsa047241.78689210
14Gastric acid secretion_Homo sapiens_hsa049711.72799412
15Salivary secretion_Homo sapiens_hsa049701.72205317
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.71859554
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.70190150
18Dopaminergic synapse_Homo sapiens_hsa047281.69980688
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.64700726
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59865865
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.58910794
22Cholinergic synapse_Homo sapiens_hsa047251.53576456
23Vitamin B6 metabolism_Homo sapiens_hsa007501.53506842
24Morphine addiction_Homo sapiens_hsa050321.51504467
25Type II diabetes mellitus_Homo sapiens_hsa049301.48549938
26Cocaine addiction_Homo sapiens_hsa050301.46652669
27GnRH signaling pathway_Homo sapiens_hsa049121.41681023
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.41018072
29Estrogen signaling pathway_Homo sapiens_hsa049151.34299173
30Glioma_Homo sapiens_hsa052141.30498076
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29261781
32Gap junction_Homo sapiens_hsa045401.28376427
33Oxytocin signaling pathway_Homo sapiens_hsa049211.26174520
34Renin secretion_Homo sapiens_hsa049241.24811854
35Taste transduction_Homo sapiens_hsa047421.23033843
36Long-term depression_Homo sapiens_hsa047301.21296113
37Other glycan degradation_Homo sapiens_hsa005111.16778296
38Bile secretion_Homo sapiens_hsa049761.16707199
39Fructose and mannose metabolism_Homo sapiens_hsa000511.16599306
40Phenylalanine metabolism_Homo sapiens_hsa003601.16447337
41Chronic myeloid leukemia_Homo sapiens_hsa052201.15979938
42Melanogenesis_Homo sapiens_hsa049161.13489123
43ErbB signaling pathway_Homo sapiens_hsa040121.10529299
44Serotonergic synapse_Homo sapiens_hsa047261.09269343
45Thyroid cancer_Homo sapiens_hsa052161.07606106
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05779186
47Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.04677900
48Axon guidance_Homo sapiens_hsa043601.04631966
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04099326
50Glycosaminoglycan degradation_Homo sapiens_hsa005311.03788405
51Fatty acid biosynthesis_Homo sapiens_hsa000611.02859485
52Thyroid hormone synthesis_Homo sapiens_hsa049181.01326860
53Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.01195676
54Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00990705
55Dorso-ventral axis formation_Homo sapiens_hsa043200.99668230
56Endometrial cancer_Homo sapiens_hsa052130.99122065
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.98351158
58cAMP signaling pathway_Homo sapiens_hsa040240.98314351
59Pancreatic secretion_Homo sapiens_hsa049720.97611743
60Histidine metabolism_Homo sapiens_hsa003400.95725931
61mTOR signaling pathway_Homo sapiens_hsa041500.95658397
62Calcium signaling pathway_Homo sapiens_hsa040200.93002511
63Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91671481
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90368221
65Sulfur relay system_Homo sapiens_hsa041220.87172613
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.86918040
67Galactose metabolism_Homo sapiens_hsa000520.86380159
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82712723
69Arginine biosynthesis_Homo sapiens_hsa002200.82352424
70Small cell lung cancer_Homo sapiens_hsa052220.82175331
71Tight junction_Homo sapiens_hsa045300.81415515
72Vibrio cholerae infection_Homo sapiens_hsa051100.79300031
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.79080826
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.79058532
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77700068
76Bladder cancer_Homo sapiens_hsa052190.77193496
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.76565403
78Hippo signaling pathway_Homo sapiens_hsa043900.76448320
79Arginine and proline metabolism_Homo sapiens_hsa003300.75896027
80Dilated cardiomyopathy_Homo sapiens_hsa054140.75785562
81Collecting duct acid secretion_Homo sapiens_hsa049660.75715509
82VEGF signaling pathway_Homo sapiens_hsa043700.75572301
83Glucagon signaling pathway_Homo sapiens_hsa049220.73908831
84Acute myeloid leukemia_Homo sapiens_hsa052210.73508721
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.72892773
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71768406
87Maturity onset diabetes of the young_Homo sapiens_hsa049500.69670103
88Pentose phosphate pathway_Homo sapiens_hsa000300.69488002
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69459985
90Insulin signaling pathway_Homo sapiens_hsa049100.68504582
91MicroRNAs in cancer_Homo sapiens_hsa052060.68488579
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67768592
93Choline metabolism in cancer_Homo sapiens_hsa052310.66670694
94Biosynthesis of amino acids_Homo sapiens_hsa012300.65250868
95Basal cell carcinoma_Homo sapiens_hsa052170.65021548
96Proteoglycans in cancer_Homo sapiens_hsa052050.63419945
97Rap1 signaling pathway_Homo sapiens_hsa040150.63047497
98Renal cell carcinoma_Homo sapiens_hsa052110.61345694
99Pancreatic cancer_Homo sapiens_hsa052120.60936683
100Focal adhesion_Homo sapiens_hsa045100.60660671
101Sphingolipid metabolism_Homo sapiens_hsa006000.60092686
102Leukocyte transendothelial migration_Homo sapiens_hsa046700.59947916
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59535353
104Lysine degradation_Homo sapiens_hsa003100.59514795
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.59273131
106MAPK signaling pathway_Homo sapiens_hsa040100.59182776
107Non-small cell lung cancer_Homo sapiens_hsa052230.58051257
108Hepatitis C_Homo sapiens_hsa051600.57702143
109Endocytosis_Homo sapiens_hsa041440.57483736
110Adherens junction_Homo sapiens_hsa045200.57170314
111Central carbon metabolism in cancer_Homo sapiens_hsa052300.56670061
112Amoebiasis_Homo sapiens_hsa051460.56577817
113Hedgehog signaling pathway_Homo sapiens_hsa043400.55907526
114Inositol phosphate metabolism_Homo sapiens_hsa005620.55631856
115Protein digestion and absorption_Homo sapiens_hsa049740.55130094
116Wnt signaling pathway_Homo sapiens_hsa043100.54733101
117Oocyte meiosis_Homo sapiens_hsa041140.54483358
118Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52761955
119Prion diseases_Homo sapiens_hsa050200.52594102
120Ras signaling pathway_Homo sapiens_hsa040140.52488989
121Prolactin signaling pathway_Homo sapiens_hsa049170.52103812
122Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51660775
123Mineral absorption_Homo sapiens_hsa049780.48171419
124Insulin resistance_Homo sapiens_hsa049310.46735032
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44972007
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42118613
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.39983047
128Ovarian steroidogenesis_Homo sapiens_hsa049130.39828548
129ECM-receptor interaction_Homo sapiens_hsa045120.39759311
130AMPK signaling pathway_Homo sapiens_hsa041520.39660875
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39580192

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