CEP131

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)9.67088739
2transcription from mitochondrial promoter (GO:0006390)7.27121710
3proline metabolic process (GO:0006560)7.05646190
4embryonic process involved in female pregnancy (GO:0060136)6.58849324
5replication fork processing (GO:0031297)6.50299596
6establishment of apical/basal cell polarity (GO:0035089)6.35635830
7DNA deamination (GO:0045006)5.96651134
8positive regulation of protein homooligomerization (GO:0032464)5.93566686
9regulation of integrin activation (GO:0033623)5.59476758
10establishment or maintenance of monopolar cell polarity (GO:0061339)5.56909709
11establishment of monopolar cell polarity (GO:0061162)5.56909709
12oxidative demethylation (GO:0070989)5.53772053
13maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)5.41021901
14regulation of protein homooligomerization (GO:0032462)5.27677311
15mitochondrial DNA metabolic process (GO:0032042)5.00721519
16mitotic G1 DNA damage checkpoint (GO:0031571)4.94191849
17somatic diversification of immune receptors via somatic mutation (GO:0002566)4.89516908
18somatic hypermutation of immunoglobulin genes (GO:0016446)4.89516908
19DNA strand renaturation (GO:0000733)4.88485308
20nucleosome disassembly (GO:0006337)4.84968356
21protein-DNA complex disassembly (GO:0032986)4.84968356
22regulation of translational fidelity (GO:0006450)4.81075694
23mitotic chromosome condensation (GO:0007076)4.73993293
24DNA unwinding involved in DNA replication (GO:0006268)4.58836546
25negative regulation of JAK-STAT cascade (GO:0046426)4.51450134
26poly(A)+ mRNA export from nucleus (GO:0016973)4.44999888
27spliceosomal tri-snRNP complex assembly (GO:0000244)4.44085018
28planar cell polarity pathway involved in neural tube closure (GO:0090179)4.38424634
29mRNA cleavage (GO:0006379)4.33311787
30G1 DNA damage checkpoint (GO:0044783)4.32754905
31mitotic G1/S transition checkpoint (GO:0044819)4.31230369
32negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.28665357
33negative regulation of cell cycle arrest (GO:0071157)4.25954094
34ribosomal small subunit biogenesis (GO:0042274)4.25617837
35regulation of mammary gland epithelial cell proliferation (GO:0033599)4.19258531
36embryonic placenta development (GO:0001892)4.12686998
37viral mRNA export from host cell nucleus (GO:0046784)4.12030777
38regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.99110227
39heterochromatin organization (GO:0070828)3.98652721
40dosage compensation (GO:0007549)3.98301168
41convergent extension (GO:0060026)3.91101841
42base-excision repair (GO:0006284)3.90095500
43negative regulation of Ras GTPase activity (GO:0034261)3.87445555
44cellular response to ATP (GO:0071318)3.85919802
45embryonic camera-type eye development (GO:0031076)3.80653262
46regulation of RNA export from nucleus (GO:0046831)3.74741202
47glutamine family amino acid biosynthetic process (GO:0009084)3.74022085
48histone H4-K12 acetylation (GO:0043983)3.72328406
49DNA integration (GO:0015074)3.72024817
50negative regulation of protein oligomerization (GO:0032460)3.71556192
51negative regulation of mRNA processing (GO:0050686)3.71109182
52positive regulation of mitotic sister chromatid separation (GO:1901970)3.69979633
53positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.69979633
54positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.69979633
55regulation of sister chromatid cohesion (GO:0007063)3.64902225
56regulation of NFAT protein import into nucleus (GO:0051532)3.60215154
57formation of translation preinitiation complex (GO:0001731)3.59933346
58establishment of protein localization to mitochondrial membrane (GO:0090151)3.56833445
59double-strand break repair via nonhomologous end joining (GO:0006303)3.53744422
60non-recombinational repair (GO:0000726)3.53744422
61apoptotic process involved in morphogenesis (GO:0060561)3.52959697
62anatomical structure regression (GO:0060033)3.52604417
63telomere maintenance via semi-conservative replication (GO:0032201)3.51611643
64regulation of gene silencing by RNA (GO:0060966)3.51106563
65regulation of posttranscriptional gene silencing (GO:0060147)3.51106563
66regulation of gene silencing by miRNA (GO:0060964)3.51106563
67pre-miRNA processing (GO:0031054)3.48605385
68positive regulation of developmental pigmentation (GO:0048087)3.48516577
69positive regulation by host of viral transcription (GO:0043923)3.47146016
70DNA topological change (GO:0006265)3.45930253
71termination of RNA polymerase II transcription (GO:0006369)3.44260830
72glial cell migration (GO:0008347)3.44016870
73epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.42598078
74positive regulation of protein oligomerization (GO:0032461)3.41133659
75nucleotide-excision repair, DNA gap filling (GO:0006297)3.39569438
76negative regulation of cell size (GO:0045792)3.39373858
77regulation of protein oligomerization (GO:0032459)3.35713753
78viral transcription (GO:0019083)3.35361431
79trophectodermal cell differentiation (GO:0001829)3.35014427
80face development (GO:0060324)3.34861049
81negative regulation of fatty acid biosynthetic process (GO:0045717)3.30500626
82regulation of DNA damage checkpoint (GO:2000001)3.30067892
83chromosome condensation (GO:0030261)3.29703728
84peptidyl-lysine dimethylation (GO:0018027)3.27493664
85negative regulation of RNA splicing (GO:0033119)3.26837388
86negative regulation of erythrocyte differentiation (GO:0045647)3.26460211
87nodal signaling pathway (GO:0038092)3.26009253
88mitochondrial RNA metabolic process (GO:0000959)3.24933529
89regulation of chromatin binding (GO:0035561)3.24534747
90intracellular estrogen receptor signaling pathway (GO:0030520)3.22948469
91negative regulation of DNA-templated transcription, elongation (GO:0032785)3.21120009
92negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.20428022
93cellular response to zinc ion (GO:0071294)3.19525142
94peptidyl-arginine omega-N-methylation (GO:0035247)3.18331976
95L-serine metabolic process (GO:0006563)3.14515260
96signal complex assembly (GO:0007172)3.11195351
97mitotic sister chromatid segregation (GO:0000070)3.11179529
98semaphorin-plexin signaling pathway (GO:0071526)3.11156104
99protein retention in ER lumen (GO:0006621)3.10277065
100regulation of hippo signaling (GO:0035330)3.10090509
101activation of Rac GTPase activity (GO:0032863)3.09124984
102negative regulation of mRNA metabolic process (GO:1903312)3.08114418
103snRNA metabolic process (GO:0016073)3.07764528
104DNA double-strand break processing (GO:0000729)3.06811312
105regulation of cAMP-dependent protein kinase activity (GO:2000479)3.06338086
106cell migration in hindbrain (GO:0021535)3.06213084
1073-UTR-mediated mRNA stabilization (GO:0070935)3.06196153
108DNA replication initiation (GO:0006270)3.06047962
109base-excision repair, AP site formation (GO:0006285)3.05907901
110labyrinthine layer development (GO:0060711)3.04668935
111translational termination (GO:0006415)3.04203098
112regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.04125374
113ncRNA 3-end processing (GO:0043628)3.03896067
114histone H4 deacetylation (GO:0070933)3.03143675
115meiotic chromosome segregation (GO:0045132)3.02246651
116regulation of double-strand break repair (GO:2000779)3.02113419
117regulation of cell size (GO:0008361)3.00032498
118nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.98817122
119DNA duplex unwinding (GO:0032508)2.98694995
120DNA strand elongation involved in DNA replication (GO:0006271)2.98689539
121mRNA polyadenylation (GO:0006378)2.96976701
122DNA ligation (GO:0006266)2.94829796
123regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.94157743
124protein targeting to lysosome (GO:0006622)2.93820609
125establishment of protein localization to vacuole (GO:0072666)2.93820609
126protein targeting to vacuole (GO:0006623)2.93820609
127positive regulation of chromosome segregation (GO:0051984)2.92563925
128histone arginine methylation (GO:0034969)2.91870518
129protein complex disassembly (GO:0043241)2.91439087
130RNA stabilization (GO:0043489)2.90931028
131mRNA stabilization (GO:0048255)2.90931028
132DNA strand elongation (GO:0022616)2.90769238
133pentose-phosphate shunt (GO:0006098)2.90409566
134pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.89410518
135regulation of nucleobase-containing compound transport (GO:0032239)2.89193535
136regulation of early endosome to late endosome transport (GO:2000641)2.89181836
137protein localization to endosome (GO:0036010)2.88335800
138pentose metabolic process (GO:0019321)2.87359938
139sister chromatid segregation (GO:0000819)2.86643722
140maturation of SSU-rRNA (GO:0030490)2.86535172
141chromatin assembly (GO:0031497)2.86499347
142establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.86255669
143mitochondrion transport along microtubule (GO:0047497)2.86255669
144UV protection (GO:0009650)2.86196327
145maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.83597590
146RNA localization (GO:0006403)2.80291982
147adherens junction assembly (GO:0034333)2.79521734
148DNA conformation change (GO:0071103)2.79178471
149activation of MAPKKK activity (GO:0000185)2.77839377
150DNA geometric change (GO:0032392)2.76972338
151DNA packaging (GO:0006323)2.76673245
152microtubule severing (GO:0051013)2.76242847
153stress granule assembly (GO:0034063)2.76024955
154snRNA processing (GO:0016180)2.74360802
155COPI coating of Golgi vesicle (GO:0048205)2.74055552
156Golgi transport vesicle coating (GO:0048200)2.74055552
157Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.73705365
158glucose catabolic process (GO:0006007)2.72565558
159translational elongation (GO:0006414)2.72243618
160cochlea morphogenesis (GO:0090103)2.72008327
161DNA synthesis involved in DNA repair (GO:0000731)2.71963278
162cell-cell junction maintenance (GO:0045217)2.71229596
163protein complex localization (GO:0031503)2.69546806
164renal system development (GO:0072001)2.68406201
165macromolecular complex disassembly (GO:0032984)2.66948595
166protein insertion into membrane (GO:0051205)2.65798801
167positive regulation of DNA-dependent DNA replication (GO:2000105)2.65604026
168histone H3 deacetylation (GO:0070932)2.65313586
169viral life cycle (GO:0019058)2.63143469
170cellular protein complex disassembly (GO:0043624)2.60084777
171protein localization to chromosome, centromeric region (GO:0071459)2.59820519
172deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.58345432
173establishment of mitochondrion localization (GO:0051654)2.57818485
174rRNA transcription (GO:0009303)2.57354779
175regulation of establishment of planar polarity (GO:0090175)2.56936563
176negative regulation of telomerase activity (GO:0051974)2.55220413
177positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.54944781
178atrioventricular valve morphogenesis (GO:0003181)2.53892540
179neural tube development (GO:0021915)2.53861549
180glucocorticoid receptor signaling pathway (GO:0042921)2.53186889
181retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.51884133

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.12826089
2ZFP281_18358816_ChIP-ChIP_MESCs_Mouse3.55540802
3SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.35690360
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.90477638
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.90477638
6KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.90477638
7SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.87145257
8RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.62180393
9VDR_21846776_ChIP-Seq_THP-1_Human2.53493489
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.52130547
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.50178893
12SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.35910527
13DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.31113948
14LXR_22292898_ChIP-Seq_THP-1_Human2.28982917
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.26671564
16NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.26560278
17E2F7_22180533_ChIP-Seq_HELA_Human2.21761180
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.19963333
19KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.18516519
20MYC_18555785_ChIP-Seq_MESCs_Mouse2.17155584
21POU5F1_16518401_ChIP-PET_MESCs_Mouse2.12497593
22ERG_21242973_ChIP-ChIP_JURKAT_Human2.12144937
23NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.08924506
24MYC_22102868_ChIP-Seq_BL_Human2.05766023
25TP63_17297297_ChIP-ChIP_HaCaT_Human2.05378242
26ZFP281_18757296_ChIP-ChIP_E14_Mouse2.00871324
27SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.96181976
28MYC_19079543_ChIP-ChIP_MESCs_Mouse1.95929582
29TCF3_18692474_ChIP-Seq_MESCs_Mouse1.90029237
30ZFP281_27345836_Chip-Seq_ESCs_Mouse1.89772070
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.88950576
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.88487489
33XRN2_22483619_ChIP-Seq_HELA_Human1.85963439
34NANOG_21062744_ChIP-ChIP_HESCs_Human1.82550706
35NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.81264821
36POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.78534795
37ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.72057577
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.70368716
39KDM2B_26808549_Chip-Seq_DND41_Human1.67644589
40ZNF263_19887448_ChIP-Seq_K562_Human1.64942067
41CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.63971868
42STAT3_1855785_ChIP-Seq_MESCs_Mouse1.63862334
43TET1_21451524_ChIP-Seq_MESCs_Mouse1.62384647
44NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.61759910
45MYC_18358816_ChIP-ChIP_MESCs_Mouse1.61120322
46TCF3_18692474_ChIP-Seq_MEFs_Mouse1.60525635
47CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.60146011
48TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56353754
49CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.55800093
50PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53201607
51KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.52202932
52CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.51817187
53RACK7_27058665_Chip-Seq_MCF-7_Human1.51683776
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.50210064
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.49722641
56ESR1_15608294_ChIP-ChIP_MCF-7_Human1.49685322
57PU.1_20513432_ChIP-Seq_Bcells_Mouse1.49180107
58RARG_19884340_ChIP-ChIP_MEFs_Mouse1.49004005
59KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.48183627
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.47021765
61KLF4_18555785_ChIP-Seq_MESCs_Mouse1.46470048
62EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.45307060
63SMC4_20622854_ChIP-Seq_HELA_Human1.43384108
64EGR1_19374776_ChIP-ChIP_THP-1_Human1.39862080
65DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.38664196
66ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38645621
67MYC_19030024_ChIP-ChIP_MESCs_Mouse1.38408511
68POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.37738422
69TP53_22127205_ChIP-Seq_IMR90_Human1.37428944
70ELF1_20517297_ChIP-Seq_JURKAT_Human1.34631177
71JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.34419823
72CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.32771782
73NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31492806
74KDM2B_26808549_Chip-Seq_K562_Human1.30785371
75UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.29494016
76GABP_19822575_ChIP-Seq_HepG2_Human1.28871583
77SOX2_18692474_ChIP-Seq_MESCs_Mouse1.28284759
78ELK3_25401928_ChIP-Seq_HUVEC_Human1.27900717
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27351623
80CIITA_25753668_ChIP-Seq_RAJI_Human1.25859420
81THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25747338
82FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.25655993
83CTCF_21964334_ChIP-Seq_BJAB-B_Human1.22826404
84PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.21641183
85NELFA_20434984_ChIP-Seq_ESCs_Mouse1.21391674
86SRY_22984422_ChIP-ChIP_TESTIS_Rat1.21382339
87RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21152332
88SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.20569920
89NCOR1_26117541_ChIP-Seq_K562_Human1.20050544
90TCF7_22412390_ChIP-Seq_EML_Mouse1.19511679
91ETS1_21867929_ChIP-Seq_TH2_Mouse1.19129728
92NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.18805579
93POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.18170006
94SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.18052890
95PHF8_20622854_ChIP-Seq_HELA_Human1.17962563
96SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17870735
97NANOG_18692474_ChIP-Seq_MESCs_Mouse1.17708464
98P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17223316
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17189091
100POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16915735
101CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.16052913
102TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15596086
103P68_20966046_ChIP-Seq_HELA_Human1.15173633
104MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.15024193
105CTCF_27219007_Chip-Seq_Bcells_Human1.14329014
106SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.14157772
107MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13598458
108BCL6_27268052_Chip-Seq_Bcells_Human1.12850047
109RXRA_24833708_ChIP-Seq_LIVER_Mouse1.12640871
110RARB_24833708_ChIP-Seq_LIVER_Mouse1.12547515
111MAF_26560356_Chip-Seq_TH2_Human1.11412109
112KDM5A_27292631_Chip-Seq_BREAST_Human1.11399794
113CTCF_27219007_Chip-Seq_ERYTHROID_Human1.11211801
114NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.11197586
115KDM2B_26808549_Chip-Seq_JURKAT_Human1.10777969
116E2F1_20622854_ChIP-Seq_HELA_Human1.10404587
117BCOR_27268052_Chip-Seq_Bcells_Human1.10190390
118TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.09649818
119SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08849325
120CTCF_18555785_ChIP-Seq_MESCs_Mouse1.08496876
121SOX2_18692474_ChIP-Seq_MEFs_Mouse1.08342856
122KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.08109306
123FOXP1_21924763_ChIP-Seq_HESCs_Human1.06759332
124DCP1A_22483619_ChIP-Seq_HELA_Human1.06608271
125DNAJC2_21179169_ChIP-ChIP_NT2_Human1.05070105
126YY1_21170310_ChIP-Seq_MESCs_Mouse1.04364297
127YY1_22570637_ChIP-Seq_MALME-3M_Human1.04327051
128CREB1_26743006_Chip-Seq_LNCaP_Human1.04219159
129MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04130422
130BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04089443
131CTCF_26484167_Chip-Seq_Bcells_Mouse1.03917310
132OCT4_18692474_ChIP-Seq_MEFs_Mouse1.03674286
133RARA_24833708_ChIP-Seq_LIVER_Mouse1.02724235
134WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01997254
135SA1_27219007_Chip-Seq_ERYTHROID_Human1.01067427
136SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00964662
137SPI1_26923725_Chip-Seq_HPCs_Mouse1.00695251
138ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.00517839
139KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00233396
140TTF2_22483619_ChIP-Seq_HELA_Human0.99765794
141PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98616546
142E2F1_21310950_ChIP-Seq_MCF-7_Human0.98538542
143CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97537865
144TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96352550
145KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96339548

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.39194032
2MP0009278_abnormal_bone_marrow4.27580599
3MP0010030_abnormal_orbit_morphology4.13101286
4MP0004233_abnormal_muscle_weight3.79476159
5MP0005171_absent_coat_pigmentation3.72502724
6MP0002653_abnormal_ependyma_morphology3.49844998
7MP0003283_abnormal_digestive_organ3.25921646
8MP0004858_abnormal_nervous_system2.60191114
9MP0000566_synostosis2.49980509
10MP0003123_paternal_imprinting2.48395972
11MP0004133_heterotaxia2.45344999
12MP0008260_abnormal_autophagy2.44122983
13MP0002009_preneoplasia2.43783440
14MP0005451_abnormal_body_composition2.40548688
15MP0008995_early_reproductive_senescence2.39449202
16MP0000537_abnormal_urethra_morphology2.37064556
17MP0010094_abnormal_chromosome_stability2.28684955
18MP0003890_abnormal_embryonic-extraembry2.27066119
19MP0003119_abnormal_digestive_system2.26420042
20MP0004185_abnormal_adipocyte_glucose2.22345653
21MP0005076_abnormal_cell_differentiation2.19011684
22MP0008877_abnormal_DNA_methylation2.05479809
23MP0002249_abnormal_larynx_morphology1.98866588
24MP0006072_abnormal_retinal_apoptosis1.92022091
25MP0000678_abnormal_parathyroid_gland1.91327778
26MP0002877_abnormal_melanocyte_morpholog1.90079966
27MP0002084_abnormal_developmental_patter1.85768022
28MP0005397_hematopoietic_system_phenotyp1.84682272
29MP0001545_abnormal_hematopoietic_system1.84682272
30MP0001348_abnormal_lacrimal_gland1.82976434
31MP0002282_abnormal_trachea_morphology1.78968684
32MP0005174_abnormal_tail_pigmentation1.78756476
33MP0001293_anophthalmia1.77691304
34MP0004957_abnormal_blastocyst_morpholog1.76656252
35MP0003111_abnormal_nucleus_morphology1.68828259
36MP0002085_abnormal_embryonic_tissue1.65295238
37MP0004197_abnormal_fetal_growth/weight/1.63818896
38MP0002086_abnormal_extraembryonic_tissu1.62038910
39MP0002089_abnormal_postnatal_growth/wei1.59765085
40MP0001697_abnormal_embryo_size1.58024430
41MP0010352_gastrointestinal_tract_polyps1.57955838
42MP0003786_premature_aging1.57423798
43MP0009379_abnormal_foot_pigmentation1.47542312
44MP0003172_abnormal_lysosome_physiology1.45080003
45MP0005666_abnormal_adipose_tissue1.44622064
46MP0000003_abnormal_adipose_tissue1.42764889
47MP0005409_darkened_coat_color1.40006891
48MP0008058_abnormal_DNA_repair1.38880328
49MP0009672_abnormal_birth_weight1.37110389
50MP0001672_abnormal_embryogenesis/_devel1.33820407
51MP0005380_embryogenesis_phenotype1.33820407
52MP0008932_abnormal_embryonic_tissue1.31356869
53MP0002269_muscular_atrophy1.30492649
54MP0003567_abnormal_fetal_cardiomyocyte1.29142270
55MP0000371_diluted_coat_color1.28874857
56MP0000462_abnormal_digestive_system1.28632436
57MP0004808_abnormal_hematopoietic_stem1.27453960
58MP0005257_abnormal_intraocular_pressure1.24551414
59MP0003453_abnormal_keratinocyte_physiol1.24151882
60MP0001730_embryonic_growth_arrest1.23968517
61MP0003077_abnormal_cell_cycle1.23912048
62MP0002111_abnormal_tail_morphology1.19673423
63MP0005375_adipose_tissue_phenotype1.19625047
64MP0000579_abnormal_nail_morphology1.19306344
65MP0005501_abnormal_skin_physiology1.17487958
66MP0000350_abnormal_cell_proliferation1.16376599
67MP0002932_abnormal_joint_morphology1.14559632
68MP0000639_abnormal_adrenal_gland1.12586179
69MP0005394_taste/olfaction_phenotype1.10951343
70MP0005499_abnormal_olfactory_system1.10951343
71MP0003935_abnormal_craniofacial_develop1.09613099
72MP0000490_abnormal_crypts_of1.08234841
73MP0002080_prenatal_lethality1.07291143
74MP0005670_abnormal_white_adipose1.05969129
75MP0008007_abnormal_cellular_replicative1.05863775
76MP0001340_abnormal_eyelid_morphology1.05451779
77MP0000015_abnormal_ear_pigmentation1.04374055
78MP0002114_abnormal_axial_skeleton1.03978178
79MP0000733_abnormal_muscle_development1.03919357
80MP0000470_abnormal_stomach_morphology1.03911665
81MP0003984_embryonic_growth_retardation1.03728735
82MP0002116_abnormal_craniofacial_bone1.02106132
83MP0003705_abnormal_hypodermis_morpholog1.01968871
84MP0002088_abnormal_embryonic_growth/wei0.99758122
85MP0003755_abnormal_palate_morphology0.99707164
86MP0006292_abnormal_olfactory_placode0.99075354
87MP0005075_abnormal_melanosome_morpholog0.99042211
88MP0003136_yellow_coat_color0.98743172
89MP0010307_abnormal_tumor_latency0.96573160
90MP0003861_abnormal_nervous_system0.95306507
91MP0002075_abnormal_coat/hair_pigmentati0.92698675
92MP0003137_abnormal_impulse_conducting0.91871133
93MP0009053_abnormal_anal_canal0.90963957
94MP0000534_abnormal_ureter_morphology0.89720781
95MP0003385_abnormal_body_wall0.89283025
96MP0000467_abnormal_esophagus_morphology0.88449503
97MP0001145_abnormal_male_reproductive0.88230519
98MP0005623_abnormal_meninges_morphology0.88157486
99MP0003315_abnormal_perineum_morphology0.88140075
100MP0004264_abnormal_extraembryonic_tissu0.85883570
101MP0003693_abnormal_embryo_hatching0.85671948
102MP0000432_abnormal_head_morphology0.84385917
103MP0000955_abnormal_spinal_cord0.83227510
104MP0000759_abnormal_skeletal_muscle0.82597057
105MP0000681_abnormal_thyroid_gland0.82566959
106MP0005330_cardiomyopathy0.82329459
107MP0003566_abnormal_cell_adhesion0.81768997
108MP0004087_abnormal_muscle_fiber0.81120685
109MP0000049_abnormal_middle_ear0.80638566
110MP0003121_genomic_imprinting0.80551075
111MP0002697_abnormal_eye_size0.80487062
112MP0000762_abnormal_tongue_morphology0.80300353
113MP0005621_abnormal_cell_physiology0.79266756
114MP0003045_fibrosis0.78394630
115MP0001929_abnormal_gametogenesis0.78166535
116MP0010630_abnormal_cardiac_muscle0.76334303
117MP0001915_intracranial_hemorrhage0.75146407
118MP0005645_abnormal_hypothalamus_physiol0.74900083
119MP0009115_abnormal_fat_cell0.73964590
120MP0003942_abnormal_urinary_system0.73945744
121MP0001324_abnormal_eye_pigmentation0.73861925
122MP0005384_cellular_phenotype0.73287256
123MP0002210_abnormal_sex_determination0.73191974
124MP0002019_abnormal_tumor_incidence0.73163964
125MP0005058_abnormal_lysosome_morphology0.73133061
126MP0003122_maternal_imprinting0.73023956
127MP0000428_abnormal_craniofacial_morphol0.73014230
128MP0003948_abnormal_gas_homeostasis0.71414552
129MP0002081_perinatal_lethality0.71372178
130MP0005377_hearing/vestibular/ear_phenot0.71084836
131MP0003878_abnormal_ear_physiology0.71084836
132MP0002796_impaired_skin_barrier0.69409814
133MP0005391_vision/eye_phenotype0.69320969
134MP0001849_ear_inflammation0.69245480
135MP0002161_abnormal_fertility/fecundity0.69093829
136MP0005266_abnormal_metabolism0.68747601
137MP0003698_abnormal_male_reproductive0.68389186
138MP0000313_abnormal_cell_death0.67890442
139MP0002092_abnormal_eye_morphology0.67742360
140MP0000751_myopathy0.67590055
141MP0002751_abnormal_autonomic_nervous0.67302817
142MP0001186_pigmentation_phenotype0.67111822
143MP0003115_abnormal_respiratory_system0.66354521
144MP0000778_abnormal_nervous_system0.64127795
145MP0004811_abnormal_neuron_physiology0.63435678

Predicted human phenotypes

RankGene SetZ-score
1Rib fusion (HP:0000902)5.56421987
2Annular pancreas (HP:0001734)5.21392891
3Facial hemangioma (HP:0000329)4.90468427
4Concave nail (HP:0001598)4.75314223
5Turricephaly (HP:0000262)4.66181384
6Hyperacusis (HP:0010780)4.57739952
7Rectal fistula (HP:0100590)4.31554430
8Rectovaginal fistula (HP:0000143)4.31554430
9Ulnar bowing (HP:0003031)4.12911613
10Intestinal fistula (HP:0100819)3.95796273
11Alopecia of scalp (HP:0002293)3.95080814
12Poikiloderma (HP:0001029)3.92174422
13Male infertility (HP:0003251)3.90793444
14Coronal craniosynostosis (HP:0004440)3.83641006
15Vaginal fistula (HP:0004320)3.81640538
16Pustule (HP:0200039)3.77285685
17Short humerus (HP:0005792)3.59442089
18Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.55853543
19Hypochromic microcytic anemia (HP:0004840)3.50282212
20Aplasia/hypoplasia of the humerus (HP:0006507)3.41576919
21Intestinal atresia (HP:0011100)3.33014101
22Orthostatic hypotension (HP:0001278)3.30076890
23Tongue fasciculations (HP:0001308)3.26258902
24Increased IgM level (HP:0003496)3.25766502
25Anteriorly placed anus (HP:0001545)3.24700289
26Abnormality of the aortic arch (HP:0012303)3.20076531
27Broad distal phalanx of finger (HP:0009836)3.09620602
28Alacrima (HP:0000522)3.08746186
29Broad alveolar ridges (HP:0000187)3.04729228
30Muscle fibrillation (HP:0010546)3.04527388
31Cerebral aneurysm (HP:0004944)3.04267117
32Congenital hip dislocation (HP:0001374)3.02843931
33Insomnia (HP:0100785)2.99804859
34Short chin (HP:0000331)2.95395027
35Vertebral hypoplasia (HP:0008417)2.92444507
36Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.92444507
37Abnormality of the lower motor neuron (HP:0002366)2.92101322
38Broad face (HP:0000283)2.88339687
39Selective tooth agenesis (HP:0001592)2.86962782
40Long palpebral fissure (HP:0000637)2.86136424
41Absent radius (HP:0003974)2.85751117
42Astrocytoma (HP:0009592)2.81176943
43Abnormality of the astrocytes (HP:0100707)2.81176943
44Squamous cell carcinoma (HP:0002860)2.76647561
45Basal cell carcinoma (HP:0002671)2.76183686
46Stridor (HP:0010307)2.73791245
47Hamartoma (HP:0010566)2.72351358
48Aplasia involving forearm bones (HP:0009822)2.71760167
49Absent forearm bone (HP:0003953)2.71760167
50Pointed chin (HP:0000307)2.68142954
51Abnormality of the thoracic spine (HP:0100711)2.67385361
52Truncus arteriosus (HP:0001660)2.66013586
53High anterior hairline (HP:0009890)2.64221791
54Premature skin wrinkling (HP:0100678)2.63914643
55Abnormal hemoglobin (HP:0011902)2.63861973
56Hypotelorism (HP:0000601)2.62959206
57Volvulus (HP:0002580)2.62218616
58Upper limb amyotrophy (HP:0009129)2.61207872
59Distal upper limb amyotrophy (HP:0007149)2.61207872
60Large for gestational age (HP:0001520)2.58137085
61Achilles tendon contracture (HP:0001771)2.52867272
62Choanal stenosis (HP:0000452)2.52104889
63Dysautonomia (HP:0002459)2.49921008
64Thoracic kyphosis (HP:0002942)2.49607538
65Absent thumb (HP:0009777)2.49535979
66Albinism (HP:0001022)2.48790447
67Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.47667794
68Absent epiphyses (HP:0010577)2.47667794
69Mucopolysacchariduria (HP:0008155)2.46091345
70Urinary glycosaminoglycan excretion (HP:0003541)2.46091345
71Pancreatic islet-cell hyperplasia (HP:0004510)2.45048717
72Ragged-red muscle fibers (HP:0003200)2.44432602
73Distal lower limb amyotrophy (HP:0008944)2.43621419
74Abnormal respiratory motile cilium morphology (HP:0005938)2.42767844
75Abnormal respiratory epithelium morphology (HP:0012253)2.42767844
76Vertebral fusion (HP:0002948)2.41665026
77Abnormality of male internal genitalia (HP:0000022)2.41271031
78Reticulocytopenia (HP:0001896)2.40158954
79Abnormality of reticulocytes (HP:0004312)2.38193424
80Neoplasm of the oral cavity (HP:0100649)2.38112229
81Atelectasis (HP:0100750)2.37697749
82Reticulocytosis (HP:0001923)2.37262384
83Biconcave vertebral bodies (HP:0004586)2.36977575
84Patellar aplasia (HP:0006443)2.36755847
85Patellar dislocation (HP:0002999)2.36441600
86Bowing of the arm (HP:0006488)2.35518915
87Bowed forearm bones (HP:0003956)2.35518915
88Abnormality of the labia minora (HP:0012880)2.34163399
89Overriding aorta (HP:0002623)2.33650254
90Growth hormone excess (HP:0000845)2.32926732
91Hypoplasia of the capital femoral epiphysis (HP:0003090)2.32718970
92Disproportionate tall stature (HP:0001519)2.31960231
93Elfin facies (HP:0004428)2.31217061
94Abnormality of the calcaneus (HP:0008364)2.29884183
95Abnormality of the phalanges of the hallux (HP:0010057)2.28840982
96Abnormality of the distal phalanx of the thumb (HP:0009617)2.28587311
97Increased nuchal translucency (HP:0010880)2.28107844
98Short nail (HP:0001799)2.26024509
99Gastrointestinal atresia (HP:0002589)2.25296183
100Decreased lacrimation (HP:0000633)2.24186900
101Deep palmar crease (HP:0006191)2.23920247
102Narrow nasal bridge (HP:0000446)2.23327759
103Hypotrichosis (HP:0001006)2.21839888
104Hyperthyroidism (HP:0000836)2.21519912
105Acute lymphatic leukemia (HP:0006721)2.21413865
106Diaphragmatic weakness (HP:0009113)2.20388716
107Hypercortisolism (HP:0001578)2.20067581
108Hand muscle atrophy (HP:0009130)2.19804777
109Increased connective tissue (HP:0009025)2.19157599
110Protrusio acetabuli (HP:0003179)2.18938758
111Abnormality of mucopolysaccharide metabolism (HP:0011020)2.18878443
112Abnormality of polysaccharide metabolism (HP:0011012)2.18878443
113Abnormality of glycosaminoglycan metabolism (HP:0004371)2.18878443
114Abnormal number of incisors (HP:0011064)2.18271323
115Ependymoma (HP:0002888)2.17578272
116Flat acetabular roof (HP:0003180)2.17126013
117Aplasia/Hypoplasia of the patella (HP:0006498)2.14940433
118Glioma (HP:0009733)2.14502581
119Self-mutilation (HP:0000742)2.13526818
120Split hand (HP:0001171)2.13076941
121Obstructive sleep apnea (HP:0002870)2.12451352
122Metaphyseal cupping (HP:0003021)2.10848787
123Abnormality of the Achilles tendon (HP:0005109)2.10753641
124Renal duplication (HP:0000075)2.10433436
125Dysostosis multiplex (HP:0000943)2.10201380
126Renovascular hypertension (HP:0100817)2.07126613
127Myopathic facies (HP:0002058)2.05593003
128Partial duplication of thumb phalanx (HP:0009944)2.04842137
129Proximal placement of thumb (HP:0009623)2.04365223
130Joint stiffness (HP:0001387)2.04015685
131Increased number of teeth (HP:0011069)2.03288404
132Premature graying of hair (HP:0002216)2.03111946
133Bifid uvula (HP:0000193)2.01373693
134Short 5th finger (HP:0009237)2.00703745
135Deviation of the thumb (HP:0009603)1.98376420
136Heterotopia (HP:0002282)1.97866818
137Pseudobulbar signs (HP:0002200)1.97121177
138Shallow orbits (HP:0000586)1.96385748
139Flattened epiphyses (HP:0003071)1.96106372
140Spinal muscular atrophy (HP:0007269)1.93405983
141Polycythemia (HP:0001901)1.93319101
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.92253138
143Duplication of thumb phalanx (HP:0009942)1.92114601
144Cervical subluxation (HP:0003308)1.91858715
145Clumsiness (HP:0002312)1.91593864
146Hemivertebrae (HP:0002937)1.89451794
147Spinal rigidity (HP:0003306)1.88567797
148Asymmetric septal hypertrophy (HP:0001670)1.88556616
149Mitral regurgitation (HP:0001653)1.88243232
150Long toe (HP:0010511)1.87995168
151Hypochromic anemia (HP:0001931)1.86938610
152J-shaped sella turcica (HP:0002680)1.85870175
153Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.85853510
154Long eyelashes (HP:0000527)1.85163333
155Natal tooth (HP:0000695)1.84287012
156Infertility (HP:0000789)1.83856615
157Abnormality of the tricuspid valve (HP:0001702)1.83341664
158Abnormality of cochlea (HP:0000375)1.83176129
159Capillary hemangiomas (HP:0005306)1.83046440
160Difficulty climbing stairs (HP:0003551)1.82018603
161Precocious puberty (HP:0000826)1.81460539
162Hemorrhage of the eye (HP:0011885)1.79952303
163Centrally nucleated skeletal muscle fibers (HP:0003687)1.79466948
164Morphological abnormality of the inner ear (HP:0011390)1.78587504
165Optic nerve coloboma (HP:0000588)1.78131037
166Hypoplasia of the radius (HP:0002984)1.77651020
167Broad thumb (HP:0011304)1.77359257
168Partial duplication of the phalanx of hand (HP:0009999)1.76691233
169Anophthalmia (HP:0000528)1.76454528
170Aplasia of the musculature (HP:0100854)1.76382821
171Distal lower limb muscle weakness (HP:0009053)1.76172411
172Progressive muscle weakness (HP:0003323)1.74481683
173Bronchomalacia (HP:0002780)1.74470181
174Trigonocephaly (HP:0000243)1.74294997
175Thin ribs (HP:0000883)1.73602388
176Entropion (HP:0000621)1.73296927
177Spina bifida occulta (HP:0003298)1.72865875
178Hypertensive crisis (HP:0100735)1.71433410
179Breast hypoplasia (HP:0003187)1.69219584
180Polycystic kidney dysplasia (HP:0000113)1.68491745
18111 pairs of ribs (HP:0000878)1.68311911
182Rectal prolapse (HP:0002035)1.68052598
183Microvesicular hepatic steatosis (HP:0001414)1.67217249
184Microretrognathia (HP:0000308)1.64677454
185Thin bony cortex (HP:0002753)1.64193822
186Bowel incontinence (HP:0002607)1.61700283
187Back pain (HP:0003418)1.61124818
188Abnormality of dentin (HP:0010299)1.60080287

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK6.37756870
2DDR24.83908628
3MAPK154.63581965
4MAP3K64.00106157
5SMG13.92108267
6TYRO33.40154805
7NME23.27025057
8PINK12.99158776
9MAP3K112.92503695
10MATK2.68632623
11UHMK12.55256573
12FGR2.50274940
13PDGFRA2.31981359
14DAPK12.28791169
15BMX2.15394728
16IRAK32.06756448
17PRKD22.06443670
18DYRK1B2.05195144
19MAP3K101.73384175
20CSK1.71686168
21YES11.66277846
22CDK71.62395672
23TTN1.57372370
24MAP2K31.54376531
25PIM21.52809435
26LATS21.49925100
27FGFR41.44917899
28CDK61.39027773
29BUB11.34243323
30CDC42BPA1.28504580
31CDK121.28032762
32BRAF1.26027759
33RPS6KA21.22973982
34ERN11.21923836
35TRIB31.21745276
36PHKG11.15971875
37PHKG21.15971875
38RPS6KL11.14301100
39RPS6KC11.14301100
40ARAF1.05472157
41PIM11.02093602
42MST1R1.01689284
43CHEK21.01488090
44TRPM71.01157433
45MAPK111.00272284
46MAP3K80.99232531
47CDK80.98784329
48AKT30.97125867
49RPS6KA60.96014221
50TTK0.93297448
51NME10.92481837
52MTOR0.92204792
53NEK20.90664116
54MAP3K90.90045207
55GSK3A0.89231196
56NTRK10.84963182
57MAP2K20.84526577
58HIPK20.82630660
59DYRK30.82274266
60PLK10.80562740
61LRRK20.80413855
62MAP3K70.76897998
63PRKD30.74074795
64CDC70.72479498
65SRPK10.72294563
66RPS6KA10.71723185
67BRSK10.70104002
68SIK20.69125308
69TESK20.68735959
70AURKB0.65838789
71ATR0.65517612
72BRD40.65303852
73PRKAA10.64072136
74PTK60.60622920
75RPS6KA40.60594372
76ALK0.59858955
77PBK0.58929586
78MAP4K10.58527116
79NTRK20.58376059
80CDK20.58019525
81PRPF4B0.57600175
82VRK20.57130100
83RPS6KB20.56867240
84TAOK20.55933834
85ERBB30.55747127
86RIPK10.55616338
87CDK90.55532242
88EPHB20.54219885
89MAP3K130.53965801
90EEF2K0.53814992
91IRAK20.53000128
92STK40.49104125
93KDR0.48289998
94CAMKK10.48023893
95MAP2K40.47686868
96PDGFRB0.47682641
97RAF10.46572504
98PAK60.46340206
99CAMK1D0.45896971
100TAOK10.45846118
101NEK10.45177426
102PAK40.44111569
103STK380.44001996
104CHEK10.43100918
105TESK10.42926468
106PDPK10.42477168
107MARK30.42210649
108MAPK100.39747166
109PRKCI0.39640818
110BCKDK0.39628909
111AURKA0.39072059
112PTK20.38858307
113RPS6KB10.38115314
114EGFR0.37862647
115AKT10.37554739
116PAK20.36028524
117MAP2K60.35937600
118MAPK10.35889815
119MARK20.35884588
120MAPK140.35861754
121MET0.35585446
122CDK40.34601205
123ATM0.33805426
124CDK10.32406814
125CDK11A0.32241903
126CSNK2A10.31786864
127CDK150.31418244
128EPHA20.31061897
129WEE10.29638315
130FGFR10.28816360
131PASK0.28463665
132PRKCZ0.28177433
133CDK180.27623375
134SIK10.26996743
135TNK20.26940139
136PKN20.26671981
137MAPK30.25823134
138GSK3B0.25454287
139CSNK2A20.25257813
140DMPK0.25126404
141CAMK2B0.24112616
142CSNK1G10.23299633
143PRKDC0.22987713
144AKT20.22947879
145DYRK20.22236335
146RPS6KA30.22025790
147LATS10.20897727

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.94742744
2Mismatch repair_Homo sapiens_hsa034304.43674465
3Base excision repair_Homo sapiens_hsa034104.18830313
4DNA replication_Homo sapiens_hsa030303.51877866
5Notch signaling pathway_Homo sapiens_hsa043302.39193155
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.37099135
7Hedgehog signaling pathway_Homo sapiens_hsa043402.31818162
8mTOR signaling pathway_Homo sapiens_hsa041502.28615224
9mRNA surveillance pathway_Homo sapiens_hsa030152.28045513
10Hippo signaling pathway_Homo sapiens_hsa043902.14602428
11Other glycan degradation_Homo sapiens_hsa005112.12490050
12Ribosome_Homo sapiens_hsa030102.09557636
13Spliceosome_Homo sapiens_hsa030402.07846435
14Pentose phosphate pathway_Homo sapiens_hsa000301.97912686
15Nucleotide excision repair_Homo sapiens_hsa034201.97271767
16Cyanoamino acid metabolism_Homo sapiens_hsa004601.93939330
17RNA transport_Homo sapiens_hsa030131.90115104
18Circadian rhythm_Homo sapiens_hsa047101.79204404
19Basal cell carcinoma_Homo sapiens_hsa052171.72459705
20Adherens junction_Homo sapiens_hsa045201.62219116
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60760349
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.57812537
23Longevity regulating pathway - mammal_Homo sapiens_hsa042111.53898365
24Homologous recombination_Homo sapiens_hsa034401.52395651
25Biosynthesis of amino acids_Homo sapiens_hsa012301.51041260
26Fanconi anemia pathway_Homo sapiens_hsa034601.47913688
27Wnt signaling pathway_Homo sapiens_hsa043101.46053647
28Bladder cancer_Homo sapiens_hsa052191.44410299
29Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.43297185
30Cell cycle_Homo sapiens_hsa041101.41396389
31Oocyte meiosis_Homo sapiens_hsa041141.41067713
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.39813962
33Pyrimidine metabolism_Homo sapiens_hsa002401.39695846
34Arginine and proline metabolism_Homo sapiens_hsa003301.37503937
35VEGF signaling pathway_Homo sapiens_hsa043701.34159240
36Lysine degradation_Homo sapiens_hsa003101.33266642
37p53 signaling pathway_Homo sapiens_hsa041151.25593829
38TGF-beta signaling pathway_Homo sapiens_hsa043501.22812664
39Transcriptional misregulation in cancer_Homo sapiens_hsa052021.17991996
40Colorectal cancer_Homo sapiens_hsa052101.16410059
41Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.15867217
42Sulfur relay system_Homo sapiens_hsa041221.14888127
43Neurotrophin signaling pathway_Homo sapiens_hsa047221.13189600
44Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.09781818
45Dorso-ventral axis formation_Homo sapiens_hsa043201.09044405
46Carbon metabolism_Homo sapiens_hsa012001.02588462
47Gap junction_Homo sapiens_hsa045400.98641938
48MicroRNAs in cancer_Homo sapiens_hsa052060.97239169
49ErbB signaling pathway_Homo sapiens_hsa040120.91474375
50Fatty acid metabolism_Homo sapiens_hsa012120.90726227
51Fructose and mannose metabolism_Homo sapiens_hsa000510.90278572
52Chronic myeloid leukemia_Homo sapiens_hsa052200.89494313
53Tight junction_Homo sapiens_hsa045300.89039820
54Prion diseases_Homo sapiens_hsa050200.88315755
55Shigellosis_Homo sapiens_hsa051310.84787310
56Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84768313
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.84347596
58Central carbon metabolism in cancer_Homo sapiens_hsa052300.82247761
59Apoptosis_Homo sapiens_hsa042100.80728410
60Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.78986643
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78726461
62AMPK signaling pathway_Homo sapiens_hsa041520.77333945
63Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74320671
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73696152
65Insulin signaling pathway_Homo sapiens_hsa049100.73419896
66Choline metabolism in cancer_Homo sapiens_hsa052310.72793191
67B cell receptor signaling pathway_Homo sapiens_hsa046620.70807211
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70123360
69Epstein-Barr virus infection_Homo sapiens_hsa051690.69929907
70Endometrial cancer_Homo sapiens_hsa052130.67362743
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.67053963
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65759493
73Glycosaminoglycan degradation_Homo sapiens_hsa005310.65742586
74Estrogen signaling pathway_Homo sapiens_hsa049150.64909127
75Alcoholism_Homo sapiens_hsa050340.64231425
76Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.63407326
77Thyroid cancer_Homo sapiens_hsa052160.61001587
78Small cell lung cancer_Homo sapiens_hsa052220.60510851
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.59888035
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58944948
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58905531
82Proteoglycans in cancer_Homo sapiens_hsa052050.57636872
83Acute myeloid leukemia_Homo sapiens_hsa052210.57626729
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55135534
85Arginine biosynthesis_Homo sapiens_hsa002200.54614869
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54358272
87Viral myocarditis_Homo sapiens_hsa054160.53854078
88Viral carcinogenesis_Homo sapiens_hsa052030.53739610
89N-Glycan biosynthesis_Homo sapiens_hsa005100.53251434
90Hepatitis B_Homo sapiens_hsa051610.52194199
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50919777
92GnRH signaling pathway_Homo sapiens_hsa049120.50600911
93AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49835697
94MAPK signaling pathway_Homo sapiens_hsa040100.48632186
95Olfactory transduction_Homo sapiens_hsa047400.48531612
96Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48273667
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47552183
98RNA polymerase_Homo sapiens_hsa030200.46623679
99Prolactin signaling pathway_Homo sapiens_hsa049170.46269328
100Melanoma_Homo sapiens_hsa052180.46244211
101Glucagon signaling pathway_Homo sapiens_hsa049220.46073131
102Inositol phosphate metabolism_Homo sapiens_hsa005620.45872346
103Salmonella infection_Homo sapiens_hsa051320.43934444
104Melanogenesis_Homo sapiens_hsa049160.42842943
105Focal adhesion_Homo sapiens_hsa045100.42752312
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42224038
107Glioma_Homo sapiens_hsa052140.42161185
108HTLV-I infection_Homo sapiens_hsa051660.40685404
109Pathways in cancer_Homo sapiens_hsa052000.38792804
110Endocytosis_Homo sapiens_hsa041440.38770392
111Non-small cell lung cancer_Homo sapiens_hsa052230.37922136
112Systemic lupus erythematosus_Homo sapiens_hsa053220.37555093
113Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36090901
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.35247665
115Folate biosynthesis_Homo sapiens_hsa007900.33192456
116Galactose metabolism_Homo sapiens_hsa000520.32495586
117Rap1 signaling pathway_Homo sapiens_hsa040150.32491950
118Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.31942525
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.30323935
120HIF-1 signaling pathway_Homo sapiens_hsa040660.27503133
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.26721103
122One carbon pool by folate_Homo sapiens_hsa006700.26052153
123Pancreatic cancer_Homo sapiens_hsa052120.25476643
124Prostate cancer_Homo sapiens_hsa052150.25120252
125Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.24429481
126Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23757656
127RNA degradation_Homo sapiens_hsa030180.19944095
128Amphetamine addiction_Homo sapiens_hsa050310.19585472
129Axon guidance_Homo sapiens_hsa043600.18111061
130Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18090809
131Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.17913281

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