CEP128

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)8.98885169
2fusion of sperm to egg plasma membrane (GO:0007342)7.16067452
3axonemal dynein complex assembly (GO:0070286)6.93800044
4sperm motility (GO:0030317)6.90944752
5multicellular organism reproduction (GO:0032504)6.43793873
6acrosome assembly (GO:0001675)6.42297802
7sperm-egg recognition (GO:0035036)6.27645539
8motile cilium assembly (GO:0044458)6.21206547
9acrosome reaction (GO:0007340)5.93881449
10epithelial cilium movement (GO:0003351)5.80004324
11cell-cell recognition (GO:0009988)5.76357315
12binding of sperm to zona pellucida (GO:0007339)5.63350821
13microtubule depolymerization (GO:0007019)5.57506047
14spermatid development (GO:0007286)5.26443125
15piRNA metabolic process (GO:0034587)5.25246529
16plasma membrane fusion (GO:0045026)5.22788005
17cell wall macromolecule metabolic process (GO:0044036)5.22534113
18cell wall macromolecule catabolic process (GO:0016998)5.22534113
19cilium movement (GO:0003341)5.12684663
20reproduction (GO:0000003)4.94011641
21protein localization to kinetochore (GO:0034501)4.80885652
22replication fork processing (GO:0031297)4.78914609
23epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.78697807
24mitotic sister chromatid cohesion (GO:0007064)4.71262582
25male meiosis (GO:0007140)4.70855888
26single fertilization (GO:0007338)4.56920277
27regulation of cilium movement (GO:0003352)4.53987332
28mitotic metaphase plate congression (GO:0007080)4.47769415
29metaphase plate congression (GO:0051310)4.33267016
30kinetochore organization (GO:0051383)4.27455722
31DNA strand elongation (GO:0022616)4.21239442
32centriole assembly (GO:0098534)4.19160825
33regulation of centrosome cycle (GO:0046605)4.18672942
34maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.17587873
35protein K6-linked ubiquitination (GO:0085020)4.06533785
36DNA unwinding involved in DNA replication (GO:0006268)4.01763518
37chromosome segregation (GO:0007059)3.99210236
38regulation of DNA endoreduplication (GO:0032875)3.98253824
39DNA replication initiation (GO:0006270)3.91564150
40centriole replication (GO:0007099)3.91020254
41synaptonemal complex organization (GO:0070193)3.88597908
42regulation of centrosome duplication (GO:0010824)3.88593499
43regulation of chromosome segregation (GO:0051983)3.85163401
44spindle checkpoint (GO:0031577)3.82099729
45synaptonemal complex assembly (GO:0007130)3.82041965
46meiotic chromosome segregation (GO:0045132)3.81166726
47DNA replication checkpoint (GO:0000076)3.79616050
48nuclear pore complex assembly (GO:0051292)3.76029548
49establishment of chromosome localization (GO:0051303)3.74477012
50ventricular system development (GO:0021591)3.72929428
51negative regulation of chromosome segregation (GO:0051985)3.69801973
52fertilization (GO:0009566)3.64820621
53histone exchange (GO:0043486)3.64113046
54regulation of sister chromatid segregation (GO:0033045)3.63870146
55regulation of mitotic sister chromatid separation (GO:0010965)3.63870146
56regulation of mitotic sister chromatid segregation (GO:0033047)3.63870146
57mitotic nuclear envelope disassembly (GO:0007077)3.62794691
58regulation of spindle organization (GO:0090224)3.62690483
59microtubule organizing center organization (GO:0031023)3.62381261
60regulation of mitotic metaphase/anaphase transition (GO:0030071)3.60731262
61regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.60731262
62nucleotide-excision repair, DNA gap filling (GO:0006297)3.59194314
63chromosome organization involved in meiosis (GO:0070192)3.58829933
64kinetochore assembly (GO:0051382)3.58825650
65DNA methylation involved in gamete generation (GO:0043046)3.58734114
66regulation of spindle checkpoint (GO:0090231)3.58607502
67negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.58440114
68negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.58440114
69negative regulation of mitotic sister chromatid segregation (GO:0033048)3.58440114
70negative regulation of mitotic sister chromatid separation (GO:2000816)3.58440114
71negative regulation of sister chromatid segregation (GO:0033046)3.58440114
72meiotic cell cycle (GO:0051321)3.55737759
73mitotic G2/M transition checkpoint (GO:0044818)3.52750406
74mitotic spindle checkpoint (GO:0071174)3.51243417
75male meiosis I (GO:0007141)3.51048087
76male gamete generation (GO:0048232)3.50646006
77spermatogenesis (GO:0007283)3.50583226
78sperm capacitation (GO:0048240)3.50294367
79recombinational repair (GO:0000725)3.50250716
80double-strand break repair via homologous recombination (GO:0000724)3.49111052
81regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.47623622
82DNA conformation change (GO:0071103)3.47029162
83microtubule nucleation (GO:0007020)3.46414910
84positive regulation of chromosome segregation (GO:0051984)3.44848175
85mitotic spindle assembly checkpoint (GO:0007094)3.44418475
86pore complex assembly (GO:0046931)3.43462907
87spindle assembly checkpoint (GO:0071173)3.42552761
88DNA packaging (GO:0006323)3.41855259
89protein localization to chromosome, centromeric region (GO:0071459)3.41554016
90protein localization to chromosome (GO:0034502)3.41113631
91double-strand break repair via nonhomologous end joining (GO:0006303)3.38727073
92non-recombinational repair (GO:0000726)3.38727073
93microtubule polymerization or depolymerization (GO:0031109)3.38262129
94membrane disassembly (GO:0030397)3.34734943
95nuclear envelope disassembly (GO:0051081)3.34734943
96centrosome duplication (GO:0051298)3.33869942
97translesion synthesis (GO:0019985)3.30989971
98regulation of histone H3-K9 methylation (GO:0051570)3.28495943
99V(D)J recombination (GO:0033151)3.27165113
100regulation of double-strand break repair via homologous recombination (GO:0010569)3.27064875
101gamete generation (GO:0007276)3.27025194
102chromatin remodeling at centromere (GO:0031055)3.25975420
103CENP-A containing nucleosome assembly (GO:0034080)3.25701723
104ATP-dependent chromatin remodeling (GO:0043044)3.25458069
105chromatin assembly or disassembly (GO:0006333)3.24494654
106meiotic nuclear division (GO:0007126)3.24379586
107regulation of mitotic spindle organization (GO:0060236)3.24318167
108chromosome condensation (GO:0030261)3.21427449
109histone-serine phosphorylation (GO:0035404)3.20338379
110regulation of centriole replication (GO:0046599)3.19375244
111mitotic sister chromatid segregation (GO:0000070)3.18563139
112regulation of sister chromatid cohesion (GO:0007063)3.16149000
113nuclear pore organization (GO:0006999)3.15179384
114microtubule anchoring (GO:0034453)3.14719318
115sister chromatid segregation (GO:0000819)3.12247081
116germ cell development (GO:0007281)3.11815654
117mitotic cell cycle (GO:0000278)3.10955458
118sister chromatid cohesion (GO:0007062)3.07590613
119regulation of mitotic spindle checkpoint (GO:1903504)3.07104373
120regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.07104373
121regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.02200244
122cellular process involved in reproduction in multicellular organism (GO:0022412)3.00301590
123negative regulation of DNA-dependent DNA replication (GO:2000104)2.96620000
124DNA replication-independent nucleosome organization (GO:0034724)2.95171978
125DNA replication-independent nucleosome assembly (GO:0006336)2.95171978
126telomere maintenance via recombination (GO:0000722)2.91070380
127synapsis (GO:0007129)2.89664898
128meiosis I (GO:0007127)2.87598534
129mitotic recombination (GO:0006312)2.85385287
130DNA ligation (GO:0006266)2.84102182
131regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.80287010
132monoubiquitinated protein deubiquitination (GO:0035520)2.79792260
133meiotic cell cycle process (GO:1903046)2.79717827
134neutrophil mediated immunity (GO:0002446)2.78688475
135organic cation transport (GO:0015695)2.75751969
136GTP biosynthetic process (GO:0006183)2.67043142
137intra-S DNA damage checkpoint (GO:0031573)2.66930498
138DNA topological change (GO:0006265)2.66220680
139centrosome organization (GO:0051297)2.65837223
140attachment of spindle microtubules to kinetochore (GO:0008608)2.65373470
141telomere maintenance via semi-conservative replication (GO:0032201)2.65328125
142DNA synthesis involved in DNA repair (GO:0000731)2.65227146
143DNA strand renaturation (GO:0000733)2.63893749
144seminiferous tubule development (GO:0072520)2.63123411
145left/right axis specification (GO:0070986)2.63111635
146DNA replication-dependent nucleosome assembly (GO:0006335)2.61652424
147DNA replication-dependent nucleosome organization (GO:0034723)2.61652424
148positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.61426413
149positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.61426413
150positive regulation of mitotic sister chromatid separation (GO:1901970)2.61426413
151DNA strand elongation involved in DNA replication (GO:0006271)2.60765317
152negative regulation of inclusion body assembly (GO:0090084)2.60684970
153histone H2A acetylation (GO:0043968)2.60508285
154DNA double-strand break processing (GO:0000729)2.59745254
155chromosome organization (GO:0051276)2.58691863
156mitotic chromosome condensation (GO:0007076)2.56481567
157protein localization to cilium (GO:0061512)2.56275520

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.59563677
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.04402459
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.24335512
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.21511001
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.10262842
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.03083327
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83983358
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.68701358
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.52869436
10AR_21909140_ChIP-Seq_LNCAP_Human2.50499329
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.39159592
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.35989421
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.33932543
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.15863633
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.99839067
16PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95002993
17IRF8_21731497_ChIP-ChIP_J774_Mouse1.91221157
18MYC_18555785_ChIP-Seq_MESCs_Mouse1.89681802
19ELK1_19687146_ChIP-ChIP_HELA_Human1.88105974
20PCGF2_27294783_Chip-Seq_NPCs_Mouse1.86349596
21SCL_19346495_ChIP-Seq_HPC-7_Human1.82793884
22PADI4_21655091_ChIP-ChIP_MCF-7_Human1.79884750
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76307198
24NFE2_27457419_Chip-Seq_LIVER_Mouse1.73529081
25CREB1_15753290_ChIP-ChIP_HEK293T_Human1.68740763
26SUZ12_27294783_Chip-Seq_NPCs_Mouse1.67969934
27ZNF274_21170338_ChIP-Seq_K562_Hela1.67586372
28IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.67002910
29EZH2_22144423_ChIP-Seq_EOC_Human1.66322110
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.63283257
31YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62632378
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.61698077
33VDR_23849224_ChIP-Seq_CD4+_Human1.60119176
34TP63_19390658_ChIP-ChIP_HaCaT_Human1.58779991
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.58592217
36EWS_26573619_Chip-Seq_HEK293_Human1.52134270
37HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51525175
38IGF1R_20145208_ChIP-Seq_DFB_Human1.51191047
39FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.50737359
40FUS_26573619_Chip-Seq_HEK293_Human1.49802961
41HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.47542492
42TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.47055740
43SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43889723
44SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.41950767
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41711019
46RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41041980
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.40435465
48MYC_19030024_ChIP-ChIP_MESCs_Mouse1.39738767
49EZH2_27294783_Chip-Seq_NPCs_Mouse1.39683983
50P53_22387025_ChIP-Seq_ESCs_Mouse1.36762333
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36351127
52SUZ12_18555785_Chip-Seq_ESCs_Mouse1.35726108
53NANOG_18555785_Chip-Seq_ESCs_Mouse1.35688410
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.34544464
55FOXP3_21729870_ChIP-Seq_TREG_Human1.34000249
56OCT4_18555785_Chip-Seq_ESCs_Mouse1.32964257
57EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.32341491
58STAT3_18555785_Chip-Seq_ESCs_Mouse1.32233687
59E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.31832332
60IRF8_27001747_Chip-Seq_BMDM_Mouse1.29653792
61MYC_18940864_ChIP-ChIP_HL60_Human1.28825427
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28786231
63MYB_21317192_ChIP-Seq_ERMYB_Mouse1.28194771
64P300_18555785_Chip-Seq_ESCs_Mouse1.28056858
65BP1_19119308_ChIP-ChIP_Hs578T_Human1.27995494
66MYCN_18555785_ChIP-Seq_MESCs_Mouse1.27849035
67TAL1_26923725_Chip-Seq_HPCs_Mouse1.27356841
68E2F1_18555785_Chip-Seq_ESCs_Mouse1.25668971
69EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.25652752
70EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.24500233
71CMYC_18555785_Chip-Seq_ESCs_Mouse1.24294311
72SALL1_21062744_ChIP-ChIP_HESCs_Human1.22575889
73POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20536046
74TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20536046
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19810922
76JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.19416619
77KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.18680684
78ETS1_20019798_ChIP-Seq_JURKAT_Human1.15578234
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.14569861
80RUNX1_27457419_Chip-Seq_LIVER_Mouse1.14269758
81CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14049042
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13865151
83ER_23166858_ChIP-Seq_MCF-7_Human1.13817700
84HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13816161
85ELF1_17652178_ChIP-ChIP_JURKAT_Human1.13717107
86GATA1_26923725_Chip-Seq_HPCs_Mouse1.13439528
87POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.13219292
88NMYC_18555785_Chip-Seq_ESCs_Mouse1.12132437
89KDM5A_27292631_Chip-Seq_BREAST_Human1.12001746
90KLF4_18555785_Chip-Seq_ESCs_Mouse1.11720999
91PU1_27457419_Chip-Seq_LIVER_Mouse1.10326168
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.10287560
93THAP11_20581084_ChIP-Seq_MESCs_Mouse1.09585938
94ESRRB_18555785_Chip-Seq_ESCs_Mouse1.09215221
95SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09211730
96CTBP1_25329375_ChIP-Seq_LNCAP_Human1.09054624
97NELFA_20434984_ChIP-Seq_ESCs_Mouse1.08661026
98TAF15_26573619_Chip-Seq_HEK293_Human1.08496390
99TTF2_22483619_ChIP-Seq_HELA_Human1.07908908
100ZFX_18555785_Chip-Seq_ESCs_Mouse1.07404517
101HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07238609
102P300_19829295_ChIP-Seq_ESCs_Human1.06343190
103MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.06259448
104SOX2_18555785_Chip-Seq_ESCs_Mouse1.05756367
105MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05725829
106FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.03932351
107TCF4_23295773_ChIP-Seq_U87_Human1.03145605
108VDR_22108803_ChIP-Seq_LS180_Human1.02967838
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02892064
110CTCF_18555785_Chip-Seq_ESCs_Mouse1.02499012
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.02311874
112IRF8_22096565_ChIP-ChIP_GC-B_Human1.02047159
113OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00434251
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.99775482
115CBP_20019798_ChIP-Seq_JUKART_Human0.99775482
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98795970
117STAT1_17558387_ChIP-Seq_HELA_Human0.98678570
118ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.98190324
119GABP_19822575_ChIP-Seq_HepG2_Human0.97429375
120DCP1A_22483619_ChIP-Seq_HELA_Human0.96984356
121STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.96410639
122GBX2_23144817_ChIP-Seq_PC3_Human0.95095699
123SMAD1_18555785_Chip-Seq_ESCs_Mouse0.94850087
124MYC_19079543_ChIP-ChIP_MESCs_Mouse0.94750837
125STAT3_23295773_ChIP-Seq_U87_Human0.93338942
126PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93338289
127POU5F1_16153702_ChIP-ChIP_HESCs_Human0.92871114
128SPI1_23547873_ChIP-Seq_NB4_Human0.92172804
129MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.91902557
130CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91634537
131IRF1_19129219_ChIP-ChIP_H3396_Human0.91172954
132POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90859604
133MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90693054
134KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.90054925
135SOX9_26525672_Chip-Seq_HEART_Mouse0.89901765
136MYB_26560356_Chip-Seq_TH1_Human0.88611005
137ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88574800
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.88086488
139AR_21572438_ChIP-Seq_LNCaP_Human0.87649402
140KDM2B_26808549_Chip-Seq_REH_Human0.87204374
141SALL4_22934838_ChIP-ChIP_CD34+_Human0.86660829
142RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.86552817
143RNF2_27304074_Chip-Seq_NSC_Mouse0.86533759
144VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.86448698
145CBX2_27304074_Chip-Seq_ESCs_Mouse0.86353435
146PKCTHETA_26484144_Chip-Seq_BREAST_Human0.86281736
147MYC_18358816_ChIP-ChIP_MESCs_Mouse0.85364442
148MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.84424909
149MYB_26560356_Chip-Seq_TH2_Human0.83991433
150UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83056541
151SOX2_16153702_ChIP-ChIP_HESCs_Human0.82262565
152FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.80674846
153SMAD4_21799915_ChIP-Seq_A2780_Human0.78000513
154CIITA_25753668_ChIP-Seq_RAJI_Human0.76058494
155NOTCH1_21737748_ChIP-Seq_TLL_Human0.73980289
156NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.72161673
157FOXM1_26456572_ChIP-Seq_MCF-7_Human0.70595875
158ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.70379481

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization7.32795119
2MP0008057_abnormal_DNA_replication4.32345405
3MP0000569_abnormal_digit_pigmentation4.18155000
4MP0008877_abnormal_DNA_methylation3.65650339
5MP0010094_abnormal_chromosome_stability3.22652330
6MP0003698_abnormal_male_reproductive3.21417948
7MP0001929_abnormal_gametogenesis2.98350413
8MP0003718_maternal_effect2.75908806
9MP0003111_abnormal_nucleus_morphology2.74222830
10MP0005174_abnormal_tail_pigmentation2.58338015
11MP0002396_abnormal_hematopoietic_system2.53744972
12MP0008058_abnormal_DNA_repair2.52995900
13MP0000015_abnormal_ear_pigmentation2.52553664
14MP0005409_darkened_coat_color2.31599647
15MP0002210_abnormal_sex_determination2.29537783
16MP0003077_abnormal_cell_cycle2.14322575
17MP0002234_abnormal_pharynx_morphology2.00443611
18MP0004808_abnormal_hematopoietic_stem1.88660936
19MP0001835_abnormal_antigen_presentation1.88405979
20MP0001145_abnormal_male_reproductive1.85371304
21MP0001545_abnormal_hematopoietic_system1.70824336
22MP0005397_hematopoietic_system_phenotyp1.70824336
23MP0003693_abnormal_embryo_hatching1.67657616
24MP0002161_abnormal_fertility/fecundity1.64985124
25MP0000653_abnormal_sex_gland1.56062061
26MP0009278_abnormal_bone_marrow1.50902475
27MP0001188_hyperpigmentation1.46799966
28MP0005171_absent_coat_pigmentation1.45933382
29MP0005075_abnormal_melanosome_morpholog1.45366890
30MP0000383_abnormal_hair_follicle1.43848909
31MP0002095_abnormal_skin_pigmentation1.43672331
32MP0008007_abnormal_cellular_replicative1.43513582
33MP0005380_embryogenesis_phenotype1.42129676
34MP0001672_abnormal_embryogenesis/_devel1.42129676
35MP0003950_abnormal_plasma_membrane1.37228988
36MP0001697_abnormal_embryo_size1.34958653
37MP0003806_abnormal_nucleotide_metabolis1.31259645
38MP0003183_abnormal_peptide_metabolism1.31054595
39MP0002398_abnormal_bone_marrow1.29138036
40MP0003787_abnormal_imprinting1.28590340
41MP0002419_abnormal_innate_immunity1.26402350
42MP0001986_abnormal_taste_sensitivity1.24815227
43MP0010307_abnormal_tumor_latency1.23316570
44MP0001730_embryonic_growth_arrest1.21997005
45MP0001800_abnormal_humoral_immune1.21486020
46MP0009785_altered_susceptibility_to1.20877716
47MP0006292_abnormal_olfactory_placode1.19867431
48MP0002085_abnormal_embryonic_tissue1.18772959
49MP0002102_abnormal_ear_morphology1.18609624
50MP0002452_abnormal_antigen_presenting1.18051593
51MP0003984_embryonic_growth_retardation1.17972720
52MP0002084_abnormal_developmental_patter1.17495233
53MP0002088_abnormal_embryonic_growth/wei1.16621742
54MP0003937_abnormal_limbs/digits/tail_de1.16095784
55MP0004197_abnormal_fetal_growth/weight/1.14778055
56MP0002420_abnormal_adaptive_immunity1.14413613
57MP0001819_abnormal_immune_cell1.13456867
58MP0005025_abnormal_response_to1.13012863
59MP0005671_abnormal_response_to1.12248760
60MP0010352_gastrointestinal_tract_polyps1.11316088
61MP0002723_abnormal_immune_serum1.10802583
62MP0005395_other_phenotype1.09541108
63MP0003172_abnormal_lysosome_physiology1.08486026
64MP0005670_abnormal_white_adipose1.08478940
65MP0003890_abnormal_embryonic-extraembry1.07031377
66MP0008789_abnormal_olfactory_epithelium1.06984181
67MP0002080_prenatal_lethality1.06778366
68MP0000703_abnormal_thymus_morphology1.06526689
69MP0002405_respiratory_system_inflammati1.06249723
70MP0002751_abnormal_autonomic_nervous1.04916365
71MP0000685_abnormal_immune_system1.02618784
72MP0000716_abnormal_immune_system1.01907291
73MP0001119_abnormal_female_reproductive0.99346582
74MP0002160_abnormal_reproductive_system0.98721178
75MP0001286_abnormal_eye_development0.98572863
76MP0003786_premature_aging0.98087021
77MP0003646_muscle_fatigue0.97932796
78MP0001293_anophthalmia0.95592317
79MP0000689_abnormal_spleen_morphology0.95447772
80MP0005000_abnormal_immune_tolerance0.95210261
81MP0008932_abnormal_embryonic_tissue0.94796294
82MP0002938_white_spotting0.94493308
83MP0005394_taste/olfaction_phenotype0.94436284
84MP0005499_abnormal_olfactory_system0.94436284
85MP0002132_abnormal_respiratory_system0.92878721
86MP0005464_abnormal_platelet_physiology0.92621407
87MP0003699_abnormal_female_reproductive0.91223261
88MP0001790_abnormal_immune_system0.90491825
89MP0005387_immune_system_phenotype0.90491825
90MP0000358_abnormal_cell_content/0.90363264
91MP0002429_abnormal_blood_cell0.90136893
92MP0009697_abnormal_copulation0.89515973
93MP0002722_abnormal_immune_system0.89162839
94MP0004957_abnormal_blastocyst_morpholog0.87561700
95MP0000647_abnormal_sebaceous_gland0.86824041
96MP0001919_abnormal_reproductive_system0.86736640
97MP0002148_abnormal_hypersensitivity_rea0.86584919
98MP0000631_abnormal_neuroendocrine_gland0.86211900
99MP0000490_abnormal_crypts_of0.84726447
100MP0003861_abnormal_nervous_system0.84587111
101MP0002009_preneoplasia0.82580746
102MP0000313_abnormal_cell_death0.81719929
103MP0002233_abnormal_nose_morphology0.81718837
104MP0009703_decreased_birth_body0.81613539
105MP0003763_abnormal_thymus_physiology0.81431737
106MP0005645_abnormal_hypothalamus_physiol0.80724931
107MP0002928_abnormal_bile_duct0.80652461
108MP0003136_yellow_coat_color0.80549249
109MP0003935_abnormal_craniofacial_develop0.80534830
110MP0005360_urolithiasis0.80203610
111MP0002086_abnormal_extraembryonic_tissu0.80156398
112MP0002075_abnormal_coat/hair_pigmentati0.79126791
113MP0002163_abnormal_gland_morphology0.78604955
114MP0000566_synostosis0.76781901
115MP0001346_abnormal_lacrimal_gland0.76394300
116MP0003755_abnormal_palate_morphology0.75131835
117MP0005076_abnormal_cell_differentiation0.74506635
118MP0000465_gastrointestinal_hemorrhage0.73178586
119MP0003221_abnormal_cardiomyocyte_apopto0.72875378
120MP0000428_abnormal_craniofacial_morphol0.72831203
121MP0003385_abnormal_body_wall0.72132393
122MP0003943_abnormal_hepatobiliary_system0.71678735
123MP0005551_abnormal_eye_electrophysiolog0.71534705
124MP0006072_abnormal_retinal_apoptosis0.70772313
125MP0005266_abnormal_metabolism0.68926711
126MP0002019_abnormal_tumor_incidence0.67956010
127MP0005384_cellular_phenotype0.67888769
128MP0000372_irregular_coat_pigmentation0.67812668
129MP0002653_abnormal_ependyma_morphology0.67625776
130MP0001324_abnormal_eye_pigmentation0.67047030
131MP0006035_abnormal_mitochondrial_morpho0.66996988
132MP0008995_early_reproductive_senescence0.66405767
133MP0000778_abnormal_nervous_system0.64091734
134MP0005253_abnormal_eye_physiology0.63975318
135MP0001186_pigmentation_phenotype0.63278427
136MP0000432_abnormal_head_morphology0.62534364
137MP0005623_abnormal_meninges_morphology0.62335919
138MP0002166_altered_tumor_susceptibility0.62320509
139MP0005391_vision/eye_phenotype0.62288725
140MP0001984_abnormal_olfaction0.60773011
141MP0000427_abnormal_hair_cycle0.59869286
142MP0005310_abnormal_salivary_gland0.57958471
143MP0000350_abnormal_cell_proliferation0.57897298
144MP0003119_abnormal_digestive_system0.57820912
145MP0008770_decreased_survivor_rate0.57449590
146MP0010678_abnormal_skin_adnexa0.56700487
147MP0002006_tumorigenesis0.56373245
148MP0005389_reproductive_system_phenotype0.55908834
149MP0004134_abnormal_chest_morphology0.55180205
150MP0001529_abnormal_vocalization0.54741351
151MP0004381_abnormal_hair_follicle0.53866939
152MP0002092_abnormal_eye_morphology0.51641386
153MP0003121_genomic_imprinting0.51166600
154MP0005257_abnormal_intraocular_pressure0.50838691
155MP0003436_decreased_susceptibility_to0.50822450

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.35067285
2Dynein arm defect of respiratory motile cilia (HP:0012255)8.16979572
3Absent/shortened dynein arms (HP:0200106)8.16979572
4Abnormal respiratory motile cilium physiology (HP:0012261)6.28231661
5Abnormal respiratory motile cilium morphology (HP:0005938)5.80484285
6Abnormal respiratory epithelium morphology (HP:0012253)5.80484285
7Abnormal ciliary motility (HP:0012262)5.21201551
8Rhinitis (HP:0012384)5.20200452
9Chromosomal breakage induced by crosslinking agents (HP:0003221)4.69988523
10Chromsome breakage (HP:0040012)4.68517436
11Chronic bronchitis (HP:0004469)4.02154634
12Nephronophthisis (HP:0000090)3.66100539
13Nasal polyposis (HP:0100582)3.58769390
14Ectopic kidney (HP:0000086)3.43867792
15Bronchiectasis (HP:0002110)3.35504440
16Volvulus (HP:0002580)3.29672881
17Infertility (HP:0000789)3.20390648
18Tubulointerstitial nephritis (HP:0001970)3.17713115
19Abnormality of the labia minora (HP:0012880)3.13410779
20Absent frontal sinuses (HP:0002688)3.05588515
21Abnormality of chromosome stability (HP:0003220)2.97113301
22Bronchitis (HP:0012387)2.96928382
23Abnormality of the renal medulla (HP:0100957)2.86432782
24Recurrent sinusitis (HP:0011108)2.80230492
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.79876787
26Abnormality of the preputium (HP:0100587)2.77497010
27Abnormality of the nasal mucosa (HP:0000433)2.66896719
28Birth length less than 3rd percentile (HP:0003561)2.65830841
29Recurrent abscess formation (HP:0002722)2.53747099
30Meckel diverticulum (HP:0002245)2.53018357
31Molar tooth sign on MRI (HP:0002419)2.52728600
32Abnormality of midbrain morphology (HP:0002418)2.52728600
33Recurrent otitis media (HP:0000403)2.51241447
34Impulsivity (HP:0100710)2.50672525
35Abnormality of the ileum (HP:0001549)2.50171305
36Clubbing of toes (HP:0100760)2.49365194
37Ependymoma (HP:0002888)2.45067999
38Cafe-au-lait spot (HP:0000957)2.36149284
39Duplicated collecting system (HP:0000081)2.34968914
40Medulloblastoma (HP:0002885)2.34653881
41Glioma (HP:0009733)2.32961568
42Nephroblastoma (Wilms tumor) (HP:0002667)2.29297640
43Abnormality of the renal collecting system (HP:0004742)2.29124813
44Sloping forehead (HP:0000340)2.28502294
45Hypoplasia of the capital femoral epiphysis (HP:0003090)2.28021048
46Recurrent bronchitis (HP:0002837)2.26777548
47Aplasia/Hypoplasia of the earlobes (HP:0009906)2.26010917
48Triphalangeal thumb (HP:0001199)2.25261737
49Increased nuchal translucency (HP:0010880)2.22910606
50Astrocytoma (HP:0009592)2.22432542
51Abnormality of the astrocytes (HP:0100707)2.22432542
52J-shaped sella turcica (HP:0002680)2.21621047
53Rhabdomyosarcoma (HP:0002859)2.20986872
54Patellar aplasia (HP:0006443)2.19911061
55Myelodysplasia (HP:0002863)2.19882197
56Abnormal spermatogenesis (HP:0008669)2.19655944
57Absent radius (HP:0003974)2.19334121
58IgM deficiency (HP:0002850)2.18160192
59Postaxial foot polydactyly (HP:0001830)2.17526467
60Pancreatic cysts (HP:0001737)2.16156877
61Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.15425699
62Renal cortical cysts (HP:0000803)2.15089385
63Arteriovenous malformation (HP:0100026)2.13521901
64Prostate neoplasm (HP:0100787)2.11954403
65Abnormality of the fingertips (HP:0001211)2.09399296
66Acute lymphatic leukemia (HP:0006721)2.09066332
67Embryonal renal neoplasm (HP:0011794)2.07968160
68Aplasia involving forearm bones (HP:0009822)2.07263416
69Absent forearm bone (HP:0003953)2.07263416
70Recurrent bacterial skin infections (HP:0005406)2.05419350
71Hypoplasia of the pons (HP:0012110)2.04745939
72Aplasia/Hypoplasia of the sternum (HP:0006714)2.04702770
73Long clavicles (HP:0000890)2.04544617
74Cortical dysplasia (HP:0002539)2.02327791
75Abnormality of DNA repair (HP:0003254)2.01310504
76Acute myeloid leukemia (HP:0004808)2.01271103
77Abnormality of the pons (HP:0007361)2.01001521
78Duodenal stenosis (HP:0100867)2.00543657
79Small intestinal stenosis (HP:0012848)2.00543657
80Retrobulbar optic neuritis (HP:0100654)1.99419370
81Optic neuritis (HP:0100653)1.99419370
82Small hand (HP:0200055)1.96013194
83Aplasia/Hypoplasia of the patella (HP:0006498)1.94765806
84Oligodactyly (hands) (HP:0001180)1.92638276
85Hypoplastic labia majora (HP:0000059)1.91396139
86Medial flaring of the eyebrow (HP:0010747)1.90933214
87Sandal gap (HP:0001852)1.89909239
88Embryonal neoplasm (HP:0002898)1.89271759
89Abnormality of the carotid arteries (HP:0005344)1.88736944
90Short thumb (HP:0009778)1.87308701
91Bone marrow hypocellularity (HP:0005528)1.86986223
92Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.86029534
93Fibular hypoplasia (HP:0003038)1.85396682
94Facial hemangioma (HP:0000329)1.84479054
95Abnormality of chromosome segregation (HP:0002916)1.84372779
96Tubulointerstitial abnormality (HP:0001969)1.84142877
97Obstructive lung disease (HP:0006536)1.83055603
98Chronic obstructive pulmonary disease (HP:0006510)1.83055603
99Abnormality of lateral ventricle (HP:0030047)1.81568355
100Choanal atresia (HP:0000453)1.81558555
101Abnormal hair whorl (HP:0010721)1.80579681
102Abnormal lung lobation (HP:0002101)1.79928285
103Abnormality of the prostate (HP:0008775)1.78568974
104Abnormality of the frontal sinuses (HP:0002687)1.78210399
105Colon cancer (HP:0003003)1.77703469
106Absent thumb (HP:0009777)1.75560768
107Sensory axonal neuropathy (HP:0003390)1.74791357
108Chronic hepatic failure (HP:0100626)1.74598075
109Absent epiphyses (HP:0010577)1.73891371
110Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.73891371
111Abnormality of the labia majora (HP:0012881)1.73233632
112Abnormality of the columella (HP:0009929)1.71789062
113Intellectual disability, moderate (HP:0002342)1.71721440
114Neoplasm of striated muscle (HP:0009728)1.70716116
115Abnormality of the septum pellucidum (HP:0007375)1.70253398
116Deformed sella turcica (HP:0002681)1.69862858
117Limb hypertonia (HP:0002509)1.69194132
118Congenital hepatic fibrosis (HP:0002612)1.66822752
119Pancreatic fibrosis (HP:0100732)1.66155163
12011 pairs of ribs (HP:0000878)1.63434490
121Squamous cell carcinoma (HP:0002860)1.63083939
122Myositis (HP:0100614)1.63034464
123Supernumerary spleens (HP:0009799)1.62887210
124Neoplasm of the oral cavity (HP:0100649)1.62819175
125Premature ovarian failure (HP:0008209)1.62720180
126Abnormal number of incisors (HP:0011064)1.62167856
127Aplastic anemia (HP:0001915)1.61762115
128Protruding tongue (HP:0010808)1.61166602
129High pitched voice (HP:0001620)1.60496015
130True hermaphroditism (HP:0010459)1.60013077
131Hepatoblastoma (HP:0002884)1.59616303
132Reticulocytopenia (HP:0001896)1.59576105
133Preaxial hand polydactyly (HP:0001177)1.59469783
134High anterior hairline (HP:0009890)1.59253278
135Gonadotropin excess (HP:0000837)1.58743685
136Abnormality of the renal cortex (HP:0011035)1.58498215
137Fair hair (HP:0002286)1.57969785
138Partial agenesis of the corpus callosum (HP:0001338)1.57651852
139Astigmatism (HP:0000483)1.57130601
140Recurrent pneumonia (HP:0006532)1.55902521
141Eczematoid dermatitis (HP:0000976)1.55132106
142Periodontitis (HP:0000704)1.54928315
143Oligohydramnios (HP:0001562)1.52864241
144Widely spaced teeth (HP:0000687)1.50045332
145Aplasia/Hypoplasia of the tongue (HP:0010295)1.49604110
146Parakeratosis (HP:0001036)1.49176517
147Abnormality of the sella turcica (HP:0002679)1.47909654
148Thyroiditis (HP:0100646)1.47193982
149Prominent nose (HP:0000448)1.46299639
150Severe visual impairment (HP:0001141)1.45836939
151Anencephaly (HP:0002323)1.44003849
152Asplenia (HP:0001746)1.42743858
153Truncal obesity (HP:0001956)1.42049571
154Slow saccadic eye movements (HP:0000514)1.41484404
155Orchitis (HP:0100796)1.41055758
156Abnormality of the duodenum (HP:0002246)1.40588497

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK33.85478533
2PDK43.85478533
3CDC73.05791643
4NEK22.62965672
5STK392.37842947
6IRAK42.33325846
7NEK12.26729291
8CCNB12.25307278
9PDK22.22940713
10TESK12.21111833
11ICK2.18233032
12PBK2.06894278
13ZAK2.02199570
14PNCK1.94082437
15CLK11.85759564
16ATR1.80937050
17FRK1.78244657
18STK161.73290597
19EIF2AK21.64634163
20MKNK21.61142541
21TXK1.58783231
22LATS11.58396409
23MKNK11.56831487
24TTK1.56646305
25CDK121.52243324
26EIF2AK11.50120116
27MAP4K21.49718993
28MAP3K141.46528015
29BRSK21.46134329
30WEE11.45407133
31CHEK21.38872432
32PLK41.38710170
33SRPK11.37803680
34PTK2B1.35703226
35VRK11.32971765
36YES11.31715081
37RIPK41.30072058
38TNIK1.26968521
39KIT1.26776202
40STK41.25135288
41BUB11.21132775
42PLK21.19075169
43MAP4K11.18466657
44DYRK31.15628855
45STK31.15222295
46TEC1.11665825
47MAPK131.10300652
48MST41.09868455
49WNK41.07103428
50PLK11.05503474
51CSF1R1.05226146
52CHEK11.04863923
53ACVR1B1.03711027
54MAP2K71.02755102
55ATM0.99762733
56INSRR0.97827430
57AURKB0.95826565
58WNK10.91601276
59BRD40.88993878
60PKN10.87278797
61MAP3K60.86536767
62SIK20.86320523
63TRPM70.86290483
64CAMK1G0.85513349
65TSSK60.84605892
66TLK10.84522682
67BTK0.83378225
68PIM10.82238147
69TAF10.81395331
70CDK70.80622474
71PIM20.80565480
72MELK0.79508639
73EPHB10.79299014
74BRSK10.77793867
75PRKD30.72771240
76TAOK30.71782379
77CAMK1D0.71602038
78PRKCQ0.70481714
79EIF2AK30.69499741
80STK100.68997932
81IRAK30.65981348
82IRAK10.64879940
83RPS6KB10.63987820
84NUAK10.62313145
85SYK0.61809666
86LYN0.61004164
87CASK0.59133290
88RPS6KB20.58685582
89RPS6KA50.58447302
90PASK0.57389884
91LCK0.56811373
92VRK20.56306957
93CDK10.56100240
94SIK30.55367194
95MAP3K100.55321884
96MARK30.54578222
97MAP3K40.53897943
98CDK80.51667693
99ADRBK20.51124242
100HCK0.50062120
101FES0.46879084
102BRAF0.46758959
103JAK30.46492271
104PLK30.45563872
105CSK0.45360271
106CDK20.43887438
107CSNK1E0.43786047
108CDK30.43620082
109SGK20.43496074
110RPS6KL10.42511910
111RPS6KC10.42511910
112IKBKE0.42418767
113NTRK20.42408127
114MINK10.42227825
115RPS6KA60.41996083
116WNK30.41377430
117TNK20.41100483
118MST1R0.41032664
119CDK40.40567786
120MAP3K90.40281639
121GSK3B0.39850795
122BCR0.39675047
123CDK90.38516834
124PRKDC0.38458052
125TRIM280.38042471
126NLK0.37942127
127FLT30.37842820
128PIK3CG0.37308729
129CSNK2A10.36967930
130CSNK1D0.36047662
131MAPK140.35765285
132TGFBR10.35399611
133CSNK2A20.35023886
134MAP3K80.31647194
135ERBB30.30569780
136MET0.29791691
137BMPR1B0.29708132
138AURKA0.29669971
139RPS6KA40.27553234
140RAF10.27266511
141DMPK0.23436934
142SCYL20.22915942
143CSNK1A1L0.22527840
144STK38L0.22444780
145EEF2K0.20544172
146PRKAA10.20004596

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.87058494
2Homologous recombination_Homo sapiens_hsa034403.53129195
3DNA replication_Homo sapiens_hsa030303.48479218
4Non-homologous end-joining_Homo sapiens_hsa034502.74204434
5Mismatch repair_Homo sapiens_hsa034302.71328481
6Base excision repair_Homo sapiens_hsa034102.47184330
7Basal transcription factors_Homo sapiens_hsa030222.28073700
8Cell cycle_Homo sapiens_hsa041102.22206495
9Nucleotide excision repair_Homo sapiens_hsa034202.14536904
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.01478035
11Systemic lupus erythematosus_Homo sapiens_hsa053221.89814663
12RNA degradation_Homo sapiens_hsa030181.65431011
13Lysine degradation_Homo sapiens_hsa003101.61042201
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.58784443
15Spliceosome_Homo sapiens_hsa030401.55900824
16RNA transport_Homo sapiens_hsa030131.49943001
17Measles_Homo sapiens_hsa051621.49795226
18Pyrimidine metabolism_Homo sapiens_hsa002401.48509759
19mRNA surveillance pathway_Homo sapiens_hsa030151.47951007
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.42026215
21Herpes simplex infection_Homo sapiens_hsa051681.27959178
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.26892567
23Hematopoietic cell lineage_Homo sapiens_hsa046401.25466838
24Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.25205664
25Purine metabolism_Homo sapiens_hsa002301.22838508
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.22715312
27Primary immunodeficiency_Homo sapiens_hsa053401.22079551
28B cell receptor signaling pathway_Homo sapiens_hsa046621.17862337
29Transcriptional misregulation in cancer_Homo sapiens_hsa052021.16268812
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.11971110
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.10507164
32Ether lipid metabolism_Homo sapiens_hsa005651.08433342
33p53 signaling pathway_Homo sapiens_hsa041151.05122891
34Viral carcinogenesis_Homo sapiens_hsa052031.01434789
35Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.00625731
36Asthma_Homo sapiens_hsa053100.96342416
37Epstein-Barr virus infection_Homo sapiens_hsa051690.96055582
38Leishmaniasis_Homo sapiens_hsa051400.95835399
39Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94211871
40alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.93928135
41Antigen processing and presentation_Homo sapiens_hsa046120.92021173
42Linoleic acid metabolism_Homo sapiens_hsa005910.91309878
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.91102248
44Osteoclast differentiation_Homo sapiens_hsa043800.90861728
45Allograft rejection_Homo sapiens_hsa053300.89542919
46Oocyte meiosis_Homo sapiens_hsa041140.89181547
47Vitamin B6 metabolism_Homo sapiens_hsa007500.88561938
48Influenza A_Homo sapiens_hsa051640.87434732
49Selenocompound metabolism_Homo sapiens_hsa004500.87291982
50Dorso-ventral axis formation_Homo sapiens_hsa043200.86522944
51Alcoholism_Homo sapiens_hsa050340.85346003
52One carbon pool by folate_Homo sapiens_hsa006700.84967275
53Phagosome_Homo sapiens_hsa041450.84079160
54Sphingolipid metabolism_Homo sapiens_hsa006000.83286061
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82166382
56Proteasome_Homo sapiens_hsa030500.79220407
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.78984357
58Olfactory transduction_Homo sapiens_hsa047400.78982159
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78627199
60Malaria_Homo sapiens_hsa051440.77976716
61Phototransduction_Homo sapiens_hsa047440.77083610
62Glycosaminoglycan degradation_Homo sapiens_hsa005310.77006794
63Propanoate metabolism_Homo sapiens_hsa006400.76612717
64Graft-versus-host disease_Homo sapiens_hsa053320.75497809
65Arachidonic acid metabolism_Homo sapiens_hsa005900.74800903
66Autoimmune thyroid disease_Homo sapiens_hsa053200.73925151
67Colorectal cancer_Homo sapiens_hsa052100.73101848
68Legionellosis_Homo sapiens_hsa051340.71896745
69Toll-like receptor signaling pathway_Homo sapiens_hsa046200.71331194
70RNA polymerase_Homo sapiens_hsa030200.66946565
71T cell receptor signaling pathway_Homo sapiens_hsa046600.65275282
72Huntingtons disease_Homo sapiens_hsa050160.64769523
73Hepatitis B_Homo sapiens_hsa051610.64150104
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.63421434
75Steroid biosynthesis_Homo sapiens_hsa001000.62145235
76Rheumatoid arthritis_Homo sapiens_hsa053230.60616923
77Tuberculosis_Homo sapiens_hsa051520.60124856
78Viral myocarditis_Homo sapiens_hsa054160.59425865
79Toxoplasmosis_Homo sapiens_hsa051450.59296095
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.58096331
81Apoptosis_Homo sapiens_hsa042100.57623871
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56994411
83HTLV-I infection_Homo sapiens_hsa051660.54368818
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54182419
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53427847
86RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.52485146
87TGF-beta signaling pathway_Homo sapiens_hsa043500.52484049
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52368627
89Pentose phosphate pathway_Homo sapiens_hsa000300.50722442
90SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50669774
91Hedgehog signaling pathway_Homo sapiens_hsa043400.49892181
92Small cell lung cancer_Homo sapiens_hsa052220.48686859
93N-Glycan biosynthesis_Homo sapiens_hsa005100.48521701
94Hippo signaling pathway_Homo sapiens_hsa043900.48120127
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48011342
96Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47838177
97Protein export_Homo sapiens_hsa030600.46999558
98Inositol phosphate metabolism_Homo sapiens_hsa005620.46093350
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45583636
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45212534
101Fatty acid biosynthesis_Homo sapiens_hsa000610.44788998
102Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43721406
103TNF signaling pathway_Homo sapiens_hsa046680.42733768
104Basal cell carcinoma_Homo sapiens_hsa052170.42521933
105Adherens junction_Homo sapiens_hsa045200.41666340
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.40715830
107Pancreatic cancer_Homo sapiens_hsa052120.40290971
108Acute myeloid leukemia_Homo sapiens_hsa052210.39342667
109Chemokine signaling pathway_Homo sapiens_hsa040620.39336827
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37677921
111Salmonella infection_Homo sapiens_hsa051320.37591955
112Shigellosis_Homo sapiens_hsa051310.36385065
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36262204
114Melanoma_Homo sapiens_hsa052180.35972396
115MicroRNAs in cancer_Homo sapiens_hsa052060.35338927
116Parkinsons disease_Homo sapiens_hsa050120.35198283
117Prostate cancer_Homo sapiens_hsa052150.34334401
118African trypanosomiasis_Homo sapiens_hsa051430.33320506
119Wnt signaling pathway_Homo sapiens_hsa043100.31940072
120Ribosome_Homo sapiens_hsa030100.31679070
121Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30917479
122Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30233546
123Butanoate metabolism_Homo sapiens_hsa006500.29843501
124Taste transduction_Homo sapiens_hsa047420.29286095
125Chronic myeloid leukemia_Homo sapiens_hsa052200.26231089
126Non-small cell lung cancer_Homo sapiens_hsa052230.25977425
127Metabolic pathways_Homo sapiens_hsa011000.25887218
128Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.23329710
129Glioma_Homo sapiens_hsa052140.23293727
130Thyroid cancer_Homo sapiens_hsa052160.21520576
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.20987223
132Pyruvate metabolism_Homo sapiens_hsa006200.19735662
133Nitrogen metabolism_Homo sapiens_hsa009100.19659932
134Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19525416
135Oxidative phosphorylation_Homo sapiens_hsa001900.15974120
136Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.14637589
137Drug metabolism - other enzymes_Homo sapiens_hsa009830.13152348
138Nicotine addiction_Homo sapiens_hsa050330.12659861
139Pathways in cancer_Homo sapiens_hsa052000.12514234
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.12396936
141FoxO signaling pathway_Homo sapiens_hsa040680.12010810
142Alzheimers disease_Homo sapiens_hsa050100.10012688
143Gap junction_Homo sapiens_hsa045400.09535521
144Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.08442054
145Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.08200116
146Glycerophospholipid metabolism_Homo sapiens_hsa005640.04743484
147Endometrial cancer_Homo sapiens_hsa052130.03319686
148Folate biosynthesis_Homo sapiens_hsa007900.03084771
149Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.02218158

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