CEP126

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)8.91109006
2fusion of sperm to egg plasma membrane (GO:0007342)8.82936304
3sperm motility (GO:0030317)8.54590783
4epithelial cilium movement (GO:0003351)8.28054800
5cilium movement (GO:0003341)7.72381156
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.57525458
7piRNA metabolic process (GO:0034587)7.49916718
8acrosome reaction (GO:0007340)7.47544741
9acrosome assembly (GO:0001675)7.41869290
10regulation of cilium movement (GO:0003352)7.24222437
11multicellular organism reproduction (GO:0032504)7.16585777
12sperm-egg recognition (GO:0035036)7.15890731
13motile cilium assembly (GO:0044458)7.14149392
14plasma membrane fusion (GO:0045026)6.92180250
15spermatid development (GO:0007286)6.78817673
16male meiosis (GO:0007140)6.72518692
17binding of sperm to zona pellucida (GO:0007339)6.57266507
18cell-cell recognition (GO:0009988)6.39128142
19synaptonemal complex organization (GO:0070193)6.21845034
20cell wall macromolecule catabolic process (GO:0016998)5.92405423
21cell wall macromolecule metabolic process (GO:0044036)5.92405423
22synaptonemal complex assembly (GO:0007130)5.81170789
23reproduction (GO:0000003)5.78437057
24negative regulation of inclusion body assembly (GO:0090084)5.27049750
25single fertilization (GO:0007338)5.20944303
26male meiosis I (GO:0007141)5.19113575
27sperm capacitation (GO:0048240)5.04582222
28ventricular system development (GO:0021591)4.93374594
29protein localization to cilium (GO:0061512)4.78456229
30DNA methylation involved in gamete generation (GO:0043046)4.70605127
31calcium ion-dependent exocytosis (GO:0017156)4.69867737
32fertilization (GO:0009566)4.68294249
33regulation of microtubule-based movement (GO:0060632)4.60936523
34spermatogenesis (GO:0007283)4.37955494
35male gamete generation (GO:0048232)4.36091268
36protein polyglutamylation (GO:0018095)4.27604195
37chromosome organization involved in meiosis (GO:0070192)4.20463566
38intraciliary transport (GO:0042073)4.13768270
39axoneme assembly (GO:0035082)4.13184810
40microtubule severing (GO:0051013)4.03970532
41germ cell development (GO:0007281)4.02609309
42gamete generation (GO:0007276)4.02607216
43meiosis I (GO:0007127)4.01008094
44regulation of inclusion body assembly (GO:0090083)3.92640562
45cellular process involved in reproduction in multicellular organism (GO:0022412)3.91740902
46meiotic nuclear division (GO:0007126)3.89687217
47behavioral response to nicotine (GO:0035095)3.69766378
48left/right pattern formation (GO:0060972)3.66377681
49cell recognition (GO:0008037)3.60059486
50nonmotile primary cilium assembly (GO:0035058)3.56586601
51microtubule depolymerization (GO:0007019)3.56075874
52microtubule-based movement (GO:0007018)3.51975767
53seminiferous tubule development (GO:0072520)3.47765991
54regulation of meiosis I (GO:0060631)3.37418933
55organic cation transport (GO:0015695)3.29771539
56negative regulation of organelle assembly (GO:1902116)3.28921731
57cilium organization (GO:0044782)3.26312921
58cilium morphogenesis (GO:0060271)3.25541455
59meiotic cell cycle (GO:0051321)3.21164732
60multicellular organismal reproductive process (GO:0048609)3.19959738
61gene silencing by RNA (GO:0031047)3.19092455
62cilium assembly (GO:0042384)3.17784933
63positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.11328545
64protein targeting to Golgi (GO:0000042)3.10979292
65cellular ketone body metabolic process (GO:0046950)3.10021330
66polyol catabolic process (GO:0046174)3.08713627
67lactate metabolic process (GO:0006089)3.06630405
68nucleoside diphosphate phosphorylation (GO:0006165)3.06498502
69membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.06417876
70retinal cone cell development (GO:0046549)3.06216310
71monoubiquitinated protein deubiquitination (GO:0035520)2.98421210
72photoreceptor cell maintenance (GO:0045494)2.95268915
73establishment of protein localization to Golgi (GO:0072600)2.94374059
74auditory behavior (GO:0031223)2.90385086
75cellular component assembly involved in morphogenesis (GO:0010927)2.89581715
76genitalia morphogenesis (GO:0035112)2.88726325
77synapsis (GO:0007129)2.88470591
78negative regulation of cytosolic calcium ion concentration (GO:0051481)2.87123101
79regulation of centriole replication (GO:0046599)2.86646717
80presynaptic membrane organization (GO:0097090)2.84371929
81membrane depolarization during action potential (GO:0086010)2.83501391
82neuronal action potential (GO:0019228)2.83287289
83spermatid nucleus differentiation (GO:0007289)2.81892709
84transmission of nerve impulse (GO:0019226)2.80237309
85mitotic sister chromatid cohesion (GO:0007064)2.79515379
86ketone body metabolic process (GO:1902224)2.79118320
87regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.78783114
88cell projection assembly (GO:0030031)2.78573523
89presynaptic membrane assembly (GO:0097105)2.78184993
90retrograde transport, vesicle recycling within Golgi (GO:0000301)2.73500605
91fucose catabolic process (GO:0019317)2.72637877
92L-fucose metabolic process (GO:0042354)2.72637877
93L-fucose catabolic process (GO:0042355)2.72637877
94glutamate receptor signaling pathway (GO:0007215)2.70788171
95ionotropic glutamate receptor signaling pathway (GO:0035235)2.70509311
96startle response (GO:0001964)2.70080130
97smoothened signaling pathway (GO:0007224)2.68937160
98determination of left/right symmetry (GO:0007368)2.68083928
99sensory perception of smell (GO:0007608)2.66511007
100microtubule bundle formation (GO:0001578)2.66362563
101negative regulation of response to food (GO:0032096)2.63811898
102negative regulation of appetite (GO:0032099)2.63811898
103GTP biosynthetic process (GO:0006183)2.63158723
104dopamine transport (GO:0015872)2.61842126
105mechanosensory behavior (GO:0007638)2.61288550
106gamma-aminobutyric acid transport (GO:0015812)2.60808937
107synaptic transmission, glutamatergic (GO:0035249)2.59555288
108neuron cell-cell adhesion (GO:0007158)2.57033091
109calcium ion import (GO:0070509)2.56696315
110multicellular organismal development (GO:0007275)2.56081519
111spinal cord motor neuron differentiation (GO:0021522)2.55583503
112centriole replication (GO:0007099)2.55351297
113brain morphogenesis (GO:0048854)2.54194362
114regulation of protein kinase A signaling (GO:0010738)2.52892632
115determination of bilateral symmetry (GO:0009855)2.51321537
116nephron epithelium morphogenesis (GO:0072088)2.48365112
117nephron tubule morphogenesis (GO:0072078)2.48365112
118serotonin metabolic process (GO:0042428)2.47610786
119inositol phosphate catabolic process (GO:0071545)2.47572162
120G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.47530339
121meiotic cell cycle process (GO:1903046)2.46585613
122neuron-neuron synaptic transmission (GO:0007270)2.45737032
123protein refolding (GO:0042026)2.44551749
124dendritic spine morphogenesis (GO:0060997)2.44056765
125specification of symmetry (GO:0009799)2.43973649
126neurotransmitter metabolic process (GO:0042133)2.43803635
127UTP biosynthetic process (GO:0006228)2.43634411
128regulation of short-term neuronal synaptic plasticity (GO:0048172)2.43266555
129postsynaptic membrane organization (GO:0001941)2.43058077
130negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.43006891
131vocalization behavior (GO:0071625)2.41915024
132primary amino compound metabolic process (GO:1901160)2.41848615
133detection of light stimulus involved in sensory perception (GO:0050962)2.41209797
134detection of light stimulus involved in visual perception (GO:0050908)2.41209797
135regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.41019082
136negative regulation of glycogen biosynthetic process (GO:0045719)2.39644989
137synaptic vesicle docking involved in exocytosis (GO:0016081)2.39266390
138protein K11-linked deubiquitination (GO:0035871)2.39032906
139glycerophospholipid catabolic process (GO:0046475)2.38424495
140cochlea development (GO:0090102)2.37976914
141insulin secretion (GO:0030073)2.37687323
142regulation of chromatin binding (GO:0035561)2.37152513
143proline transport (GO:0015824)2.36860430
144left/right axis specification (GO:0070986)2.36396991
145detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.34294893
146positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.33403437
147renal tubule morphogenesis (GO:0061333)2.32607604
148positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.32103560
149photoreceptor cell development (GO:0042461)2.32090784
150nuclear pore complex assembly (GO:0051292)2.31933662
151short-term memory (GO:0007614)2.31902531
152cornea development in camera-type eye (GO:0061303)2.31890475
153positive regulation of meiosis (GO:0045836)2.31888658
154glycerol ether metabolic process (GO:0006662)2.31663408
155regulation of neurotransmitter uptake (GO:0051580)2.31386080
156phosphorylated carbohydrate dephosphorylation (GO:0046838)2.30235461
157inositol phosphate dephosphorylation (GO:0046855)2.30235461
158chaperone-mediated protein complex assembly (GO:0051131)2.29782537
159negative regulation of synaptic transmission, GABAergic (GO:0032229)2.28371026
160neuronal action potential propagation (GO:0019227)2.28148669
161action potential (GO:0001508)2.27847949
162detection of calcium ion (GO:0005513)2.27461630
163behavioral response to ethanol (GO:0048149)2.26044258
164microtubule polymerization or depolymerization (GO:0031109)2.25279018
165water-soluble vitamin biosynthetic process (GO:0042364)2.24135585
166respiratory chain complex IV assembly (GO:0008535)2.23601204
167potassium ion transmembrane transport (GO:0071805)2.23595493
168cellular potassium ion transport (GO:0071804)2.23595493
169inner ear receptor stereocilium organization (GO:0060122)2.22850330
170urinary tract smooth muscle contraction (GO:0014848)2.21013020
171synapse assembly (GO:0007416)2.20931855
172cilium or flagellum-dependent cell motility (GO:0001539)11.7978500

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.62788373
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.21677588
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.18903185
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.03926041
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.01487545
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.60258338
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.52398164
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.44465945
9ZNF274_21170338_ChIP-Seq_K562_Hela2.16651383
10GBX2_23144817_ChIP-Seq_PC3_Human2.10031810
11REST_21632747_ChIP-Seq_MESCs_Mouse2.10016108
12IGF1R_20145208_ChIP-Seq_DFB_Human2.02980357
13RBPJ_22232070_ChIP-Seq_NCS_Mouse1.97445698
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.92436391
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.80073849
16GATA1_26923725_Chip-Seq_HPCs_Mouse1.70631281
17TAF15_26573619_Chip-Seq_HEK293_Human1.67229374
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.65904295
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.63945680
20SMAD4_21799915_ChIP-Seq_A2780_Human1.60599704
21VDR_22108803_ChIP-Seq_LS180_Human1.58779359
22TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.53718870
23POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.53718870
24CBX2_27304074_Chip-Seq_ESCs_Mouse1.53309833
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52003493
26CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.50668452
27SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48192004
28EWS_26573619_Chip-Seq_HEK293_Human1.47475804
29TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.46496587
30SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.46221929
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45444361
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.45240659
33RNF2_27304074_Chip-Seq_NSC_Mouse1.43944394
34PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43708705
35AR_21572438_ChIP-Seq_LNCaP_Human1.43536912
36OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39234961
37MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.39071284
38RARB_27405468_Chip-Seq_BRAIN_Mouse1.38017049
39SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.37634489
40EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.37404192
41TCF4_23295773_ChIP-Seq_U87_Human1.37106162
42DROSHA_22980978_ChIP-Seq_HELA_Human1.35751727
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34029500
44KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.33478118
45TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31956970
46FUS_26573619_Chip-Seq_HEK293_Human1.30811977
47TCF4_22108803_ChIP-Seq_LS180_Human1.30646835
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30557208
49MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.30304249
50WDR5_24793694_ChIP-Seq_LNCAP_Human1.30153760
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29528217
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28828225
53CBP_20019798_ChIP-Seq_JUKART_Human1.28828225
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.27465767
55TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26918475
56SALL1_21062744_ChIP-ChIP_HESCs_Human1.25552043
57TAL1_26923725_Chip-Seq_HPCs_Mouse1.25540221
58CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24705715
59FLI1_21867929_ChIP-Seq_TH2_Mouse1.22587763
60EED_16625203_ChIP-ChIP_MESCs_Mouse1.22412652
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.21582040
62STAT3_23295773_ChIP-Seq_U87_Human1.21083555
63SUZ12_27294783_Chip-Seq_ESCs_Mouse1.20133899
64AHR_22903824_ChIP-Seq_MCF-7_Human1.19332472
65RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.19321453
66RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.19103632
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.18240466
68NANOG_18555785_Chip-Seq_ESCs_Mouse1.18069576
69KDM2B_26808549_Chip-Seq_REH_Human1.18057726
70CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18030387
71SOX2_21211035_ChIP-Seq_LN229_Gbm1.17225689
72ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16252603
73CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.16203523
74BCAT_22108803_ChIP-Seq_LS180_Human1.16122761
75RNF2_27304074_Chip-Seq_ESCs_Mouse1.14960065
76EZH2_27294783_Chip-Seq_ESCs_Mouse1.14482582
77SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.14066740
78GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.13916647
79MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12844388
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12780184
81SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.12509699
82JARID2_20075857_ChIP-Seq_MESCs_Mouse1.11713990
83SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.11182403
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11104483
85ELK4_26923725_Chip-Seq_MESODERM_Mouse1.11077382
86TP53_22573176_ChIP-Seq_HFKS_Human1.10960863
87SOX2_19829295_ChIP-Seq_ESCs_Human1.10929822
88NANOG_19829295_ChIP-Seq_ESCs_Human1.10929822
89SOX9_26525672_Chip-Seq_HEART_Mouse1.10652177
90BMI1_23680149_ChIP-Seq_NPCS_Mouse1.10311558
91ER_23166858_ChIP-Seq_MCF-7_Human1.10234288
92KLF5_20875108_ChIP-Seq_MESCs_Mouse1.08736742
93SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08649496
94SMAD4_21741376_ChIP-Seq_EPCs_Human1.08462156
95PRDM14_20953172_ChIP-Seq_ESCs_Human1.08306982
96SMAD3_21741376_ChIP-Seq_ESCs_Human1.07857200
97FOXM1_26456572_ChIP-Seq_MCF-7_Human1.07439515
98EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06611930
99P300_19829295_ChIP-Seq_ESCs_Human1.05997501
100NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05649555
101EZH2_27304074_Chip-Seq_ESCs_Mouse1.05294715
102FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05270983
103FOXA1_25329375_ChIP-Seq_VCAP_Human1.05270983
104SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.04552740
105FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.04167135
106CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03643974
107GF1_26923725_Chip-Seq_HPCs_Mouse1.03606665
108MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03246468
109P53_22387025_ChIP-Seq_ESCs_Mouse1.03093651
110NFE2_27457419_Chip-Seq_LIVER_Mouse1.00218566
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98971267
112SUZ12_27294783_Chip-Seq_NPCs_Mouse0.98447299
113PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.97596025
114GF1B_26923725_Chip-Seq_HPCs_Mouse0.96924666
115PCGF2_27294783_Chip-Seq_NPCs_Mouse0.96657342
116ARNT_22903824_ChIP-Seq_MCF-7_Human0.96300340
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.95503522
118JARID2_20064375_ChIP-Seq_MESCs_Mouse0.95042276
119RUNX1_26923725_Chip-Seq_HPCs_Mouse0.94185110
120STAT1_17558387_ChIP-Seq_HELA_Human0.93751416
121CMYC_18555785_Chip-Seq_ESCs_Mouse0.93654521
122CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93522486
123E2F1_18555785_Chip-Seq_ESCs_Mouse0.92726360
124RUNX2_22187159_ChIP-Seq_PCA_Human0.92383340
125STAT6_21828071_ChIP-Seq_BEAS2B_Human0.91900259
126PIAS1_25552417_ChIP-Seq_VCAP_Human0.91816825
127P300_18555785_Chip-Seq_ESCs_Mouse0.90992264
128SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.90106072
129AR_25329375_ChIP-Seq_VCAP_Human0.89310562

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.17819668
2MP0003698_abnormal_male_reproductive3.93941689
3MP0008877_abnormal_DNA_methylation3.93469811
4MP0001929_abnormal_gametogenesis3.47638311
5MP0001984_abnormal_olfaction3.38777305
6MP0004859_abnormal_synaptic_plasticity2.89449638
7MP0002653_abnormal_ependyma_morphology2.88334265
8MP0009046_muscle_twitch2.61550314
9MP0002210_abnormal_sex_determination2.58048204
10MP0008875_abnormal_xenobiotic_pharmacok2.33083902
11MP0005623_abnormal_meninges_morphology2.26513957
12MP0003880_abnormal_central_pattern2.24452514
13MP0004270_analgesia2.22801602
14MP0002160_abnormal_reproductive_system2.22299511
15MP0002161_abnormal_fertility/fecundity2.14423488
16MP0003635_abnormal_synaptic_transmissio2.12604118
17MP0001145_abnormal_male_reproductive2.12351734
18MP0004133_heterotaxia2.12263030
19MP0003787_abnormal_imprinting2.06041804
20MP0002638_abnormal_pupillary_reflex1.88396456
21MP0000653_abnormal_sex_gland1.86944847
22MP0002837_dystrophic_cardiac_calcinosis1.85186221
23MP0002876_abnormal_thyroid_physiology1.82799779
24MP0003195_calcinosis1.80194509
25MP0002063_abnormal_learning/memory/cond1.76933679
26MP0009745_abnormal_behavioral_response1.62074179
27MP0010386_abnormal_urinary_bladder1.59499982
28MP0004885_abnormal_endolymph1.55842524
29MP0002572_abnormal_emotion/affect_behav1.54818258
30MP0002272_abnormal_nervous_system1.53123248
31MP0002909_abnormal_adrenal_gland1.50792816
32MP0002064_seizures1.50769290
33MP0001486_abnormal_startle_reflex1.44206326
34MP0002102_abnormal_ear_morphology1.42165207
35MP0002734_abnormal_mechanical_nocicepti1.41069478
36MP0002822_catalepsy1.40055426
37MP0004142_abnormal_muscle_tone1.39214126
38MP0000569_abnormal_digit_pigmentation1.38716509
39MP0008872_abnormal_physiological_respon1.38323686
40MP0001905_abnormal_dopamine_level1.37390799
41MP0005551_abnormal_eye_electrophysiolog1.32266728
42MP0001968_abnormal_touch/_nociception1.31152532
43MP0005646_abnormal_pituitary_gland1.30659599
44MP0009780_abnormal_chondrocyte_physiolo1.29950054
45MP0001485_abnormal_pinna_reflex1.27403969
46MP0002928_abnormal_bile_duct1.26258560
47MP0005423_abnormal_somatic_nervous1.25764595
48MP0001944_abnormal_pancreas_morphology1.24690306
49MP0000778_abnormal_nervous_system1.24379923
50MP0003136_yellow_coat_color1.22313606
51MP0000383_abnormal_hair_follicle1.20873148
52MP0002184_abnormal_innervation1.18317510
53MP0001440_abnormal_grooming_behavior1.18066535
54MP0000427_abnormal_hair_cycle1.17870587
55MP0005084_abnormal_gallbladder_morpholo1.16557841
56MP0002557_abnormal_social/conspecific_i1.16322220
57MP0003122_maternal_imprinting1.13894052
58MP0002067_abnormal_sensory_capabilities1.12093132
59MP0008569_lethality_at_weaning1.11743489
60MP0005394_taste/olfaction_phenotype1.09402501
61MP0005499_abnormal_olfactory_system1.09402501
62MP0004019_abnormal_vitamin_homeostasis1.09400869
63MP0005389_reproductive_system_phenotype1.08314136
64MP0008995_early_reproductive_senescence1.06889827
65MP0002277_abnormal_respiratory_mucosa1.06113380
66MP0002938_white_spotting1.04282071
67MP0003121_genomic_imprinting1.03354705
68MP0001986_abnormal_taste_sensitivity1.02704769
69MP0004811_abnormal_neuron_physiology1.02081262
70MP0002282_abnormal_trachea_morphology1.01438282
71MP0004215_abnormal_myocardial_fiber1.01359279
72MP0002152_abnormal_brain_morphology1.00812831
73MP0002693_abnormal_pancreas_physiology0.99039098
74MP0001529_abnormal_vocalization0.98525168
75MP0003123_paternal_imprinting0.97856921
76MP0004147_increased_porphyrin_level0.97817174
77MP0005645_abnormal_hypothalamus_physiol0.97781061
78MP0004742_abnormal_vestibular_system0.97634738
79MP0000026_abnormal_inner_ear0.97475602
80MP0002882_abnormal_neuron_morphology0.96258539
81MP0006072_abnormal_retinal_apoptosis0.95175847
82MP0003646_muscle_fatigue0.93471065
83MP0000955_abnormal_spinal_cord0.92389062
84MP0004233_abnormal_muscle_weight0.91740128
85MP0010329_abnormal_lipoprotein_level0.90240422
86MP0003011_delayed_dark_adaptation0.90002232
87MP0005195_abnormal_posterior_eye0.89751244
88MP0002736_abnormal_nociception_after0.88495640
89MP0003890_abnormal_embryonic-extraembry0.87348367
90MP0000566_synostosis0.85842339
91MP0003879_abnormal_hair_cell0.85512193
92MP0000372_irregular_coat_pigmentation0.85250198
93MP0004085_abnormal_heartbeat0.85220967
94MP0001963_abnormal_hearing_physiology0.84958175
95MP0001765_abnormal_ion_homeostasis0.83430246
96MP0005253_abnormal_eye_physiology0.83066318
97MP0010678_abnormal_skin_adnexa0.82657551
98MP0003861_abnormal_nervous_system0.82502801
99MP0005377_hearing/vestibular/ear_phenot0.82123679
100MP0003878_abnormal_ear_physiology0.82123679
101MP0001501_abnormal_sleep_pattern0.81137216
102MP0001756_abnormal_urination0.79286979
103MP0008789_abnormal_olfactory_epithelium0.78043550
104MP0002066_abnormal_motor_capabilities/c0.77435744
105MP0000534_abnormal_ureter_morphology0.76501157
106MP0002229_neurodegeneration0.76256448
107MP0000013_abnormal_adipose_tissue0.75899586
108MP0000631_abnormal_neuroendocrine_gland0.75787086
109MP0002735_abnormal_chemical_nociception0.75175751
110MP0006276_abnormal_autonomic_nervous0.74430973
111MP0002234_abnormal_pharynx_morphology0.74104811
112MP0002752_abnormal_somatic_nervous0.74070740
113MP0004924_abnormal_behavior0.73382912
114MP0005386_behavior/neurological_phenoty0.73382912
115MP0001188_hyperpigmentation0.72652640
116MP0008058_abnormal_DNA_repair0.70727018
117MP0001970_abnormal_pain_threshold0.67903245
118MP0000751_myopathy0.66621839
119MP0004134_abnormal_chest_morphology0.65755068
120MP0003283_abnormal_digestive_organ0.65518455
121MP0003329_amyloid_beta_deposits0.65382547
122MP0002733_abnormal_thermal_nociception0.64817127
123MP0002163_abnormal_gland_morphology0.63491317
124MP0004145_abnormal_muscle_electrophysio0.62486397
125MP0004043_abnormal_pH_regulation0.61954029
126MP0003631_nervous_system_phenotype0.61863683
127MP0001502_abnormal_circadian_rhythm0.60781734
128MP0000516_abnormal_urinary_system0.60520430
129MP0005367_renal/urinary_system_phenotyp0.60520430
130MP0008057_abnormal_DNA_replication0.60367172
131MP0003632_abnormal_nervous_system0.60109799
132MP0005379_endocrine/exocrine_gland_phen0.59045860
133MP0003633_abnormal_nervous_system0.57943724
134MP0001177_atelectasis0.57401670

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.16679338
2Abnormal respiratory motile cilium morphology (HP:0005938)7.52978379
3Abnormal respiratory epithelium morphology (HP:0012253)7.52978379
4Abnormal ciliary motility (HP:0012262)6.95374877
5Rhinitis (HP:0012384)6.82237262
6Chronic bronchitis (HP:0004469)6.09918233
7Infertility (HP:0000789)4.87055490
8Nasal polyposis (HP:0100582)3.93950393
9Nephronophthisis (HP:0000090)3.93172854
10Bronchiectasis (HP:0002110)3.82701361
11Chronic hepatic failure (HP:0100626)3.37223540
12Abnormality of the nasal mucosa (HP:0000433)3.20155424
13Abnormality of midbrain morphology (HP:0002418)3.16176218
14Molar tooth sign on MRI (HP:0002419)3.16176218
15Abnormality of the renal medulla (HP:0100957)3.11704296
16Occipital encephalocele (HP:0002085)3.11478451
17Bronchitis (HP:0012387)3.06139501
18Tubulointerstitial nephritis (HP:0001970)2.87283262
19Male infertility (HP:0003251)2.87204996
20Abnormality of the lower motor neuron (HP:0002366)2.86063400
21Medial flaring of the eyebrow (HP:0010747)2.75263254
22Hyperventilation (HP:0002883)2.55430899
23Furrowed tongue (HP:0000221)2.47899016
24Chronic sinusitis (HP:0011109)2.39212713
25Limb dystonia (HP:0002451)2.36402045
26Fibular hypoplasia (HP:0003038)2.34669561
27Sclerocornea (HP:0000647)2.33059492
28Congenital stationary night blindness (HP:0007642)2.29745482
29Retinal dysplasia (HP:0007973)2.28896642
30Abnormal rod and cone electroretinograms (HP:0008323)2.28575845
31Male pseudohermaphroditism (HP:0000037)2.27434260
32Recurrent otitis media (HP:0000403)2.24619942
33Progressive cerebellar ataxia (HP:0002073)2.23532043
34Gaze-evoked nystagmus (HP:0000640)2.21585678
35Anencephaly (HP:0002323)2.18270232
36Gait imbalance (HP:0002141)2.16960646
37Large for gestational age (HP:0001520)2.16325758
38Decreased circulating renin level (HP:0003351)2.16103227
39Tubular atrophy (HP:0000092)2.11178708
40Focal motor seizures (HP:0011153)2.10498995
41Absent frontal sinuses (HP:0002688)2.10470913
42Atonic seizures (HP:0010819)2.07945918
43Congenital primary aphakia (HP:0007707)2.07921384
44Supernumerary spleens (HP:0009799)2.07339681
45Tubulointerstitial abnormality (HP:0001969)2.05736576
46Broad-based gait (HP:0002136)2.04688782
47Pancreatic fibrosis (HP:0100732)2.03674456
48Gonadotropin excess (HP:0000837)2.03431169
49Dyschromatopsia (HP:0007641)2.02096289
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.7332741
51Dynein arm defect of respiratory motile cilia (HP:0012255)10.1465143
52Absent/shortened dynein arms (HP:0200106)10.1465143
53Abnormal spermatogenesis (HP:0008669)1.99925418
54Hypothermia (HP:0002045)1.98869438
55Median cleft lip (HP:0000161)1.96383952
56Oculomotor apraxia (HP:0000657)1.94515223
57Recurrent sinusitis (HP:0011108)1.94475898
58Postaxial hand polydactyly (HP:0001162)1.93699142
59Amyotrophic lateral sclerosis (HP:0007354)1.91613723
60Nephrogenic diabetes insipidus (HP:0009806)1.90916176
61Focal seizures (HP:0007359)1.90826319
62Postaxial foot polydactyly (HP:0001830)1.90283939
63Dialeptic seizures (HP:0011146)1.90194127
64Short ribs (HP:0000773)1.89573677
65Absent speech (HP:0001344)1.89167571
66Decreased central vision (HP:0007663)1.86372968
67Congenital hepatic fibrosis (HP:0002612)1.86107379
68Polyphagia (HP:0002591)1.86040727
69True hermaphroditism (HP:0010459)1.84263006
70Bifid tongue (HP:0010297)1.82993908
71Epileptiform EEG discharges (HP:0011182)1.79426430
72Epileptic encephalopathy (HP:0200134)1.79136677
73Myokymia (HP:0002411)1.77741071
74Facial cleft (HP:0002006)1.77589113
75Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.75784857
76Genital tract atresia (HP:0001827)1.75506626
77Stage 5 chronic kidney disease (HP:0003774)1.75318066
78Polyuria (HP:0000103)1.74869587
79EEG with generalized epileptiform discharges (HP:0011198)1.74016701
80Cerebellar dysplasia (HP:0007033)1.73075820
81Abnormality of ocular smooth pursuit (HP:0000617)1.72708305
82Vaginal atresia (HP:0000148)1.72221405
83Agitation (HP:0000713)1.70800536
84Specific learning disability (HP:0001328)1.70464972
85Narrow forehead (HP:0000341)1.70266911
86Retinitis pigmentosa (HP:0000510)1.69933680
87Prominent nasal bridge (HP:0000426)1.68493607
88Abnormality of dentin (HP:0010299)1.67710438
89Hypsarrhythmia (HP:0002521)1.67298727
90Abolished electroretinogram (ERG) (HP:0000550)1.67285197
91Attenuation of retinal blood vessels (HP:0007843)1.66228771
92Central scotoma (HP:0000603)1.65853589
93Preaxial hand polydactyly (HP:0001177)1.65820373
94Cystic liver disease (HP:0006706)1.64588921
95Lissencephaly (HP:0001339)1.61263511
96Left ventricular hypertrophy (HP:0001712)1.61192210
97Epiphyseal dysplasia (HP:0002656)1.60431975
98Aplasia/Hypoplasia of the tibia (HP:0005772)1.59410967
99Hemiparesis (HP:0001269)1.59335830
100Renal cortical cysts (HP:0000803)1.58753078
101Aplasia/Hypoplasia of the tongue (HP:0010295)1.58281566
102Abnormal drinking behavior (HP:0030082)1.57146117
103Polydipsia (HP:0001959)1.57146117
104Intestinal atresia (HP:0011100)1.55015303
105Absent rod-and cone-mediated responses on ERG (HP:0007688)1.54771585
106Bell-shaped thorax (HP:0001591)1.54622612
107Absent epiphyses (HP:0010577)1.54569313
108Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.54569313
109Congenital sensorineural hearing impairment (HP:0008527)1.53903071
110Impaired smooth pursuit (HP:0007772)1.52846950
111Poor coordination (HP:0002370)1.52787800
112Abnormality of renin-angiotensin system (HP:0000847)1.52707006
113Papillary thyroid carcinoma (HP:0002895)1.52687238
114Azoospermia (HP:0000027)1.52375120
115Short foot (HP:0001773)1.51726574
116Hyperactive renin-angiotensin system (HP:0000841)1.51718294
117Progressive macrocephaly (HP:0004481)1.51643723
118Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.51055793
119Aplasia/Hypoplasia of the fibula (HP:0006492)1.50449482
120Choroideremia (HP:0001139)1.50098071
121Absence seizures (HP:0002121)1.49401823
122Abnormality of macular pigmentation (HP:0008002)1.48776469
123Febrile seizures (HP:0002373)1.48493991
124Aplasia/Hypoplasia of the lens (HP:0008063)1.47276171
125Short femoral neck (HP:0100864)1.45104201
126Short thorax (HP:0010306)1.44539842
127Visual hallucinations (HP:0002367)1.44066519
128Impulsivity (HP:0100710)1.43807171
129Absent eyebrow (HP:0002223)1.42809711
130Impaired vibration sensation in the lower limbs (HP:0002166)1.42368057
131Type II lissencephaly (HP:0007260)1.41578531
132Irregular epiphyses (HP:0010582)1.40821714
133Action tremor (HP:0002345)1.40751566
134Tubulointerstitial fibrosis (HP:0005576)1.40259578
135Abnormality of the dental root (HP:0006486)1.39894775
136Taurodontia (HP:0000679)1.39894775
137Abnormality of permanent molar morphology (HP:0011071)1.39894775
138Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.39814930
139Pancreatic cysts (HP:0001737)1.39515257
140Abnormality of the renal cortex (HP:0011035)1.39331921
141Vitreoretinal degeneration (HP:0000655)1.39304931
142Bony spicule pigmentary retinopathy (HP:0007737)1.38972194
143Hypoplasia of the capital femoral epiphysis (HP:0003090)1.37489315

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.92742321
2PDK36.92742321
3PDK24.41526496
4PRKD34.28955973
5PNCK3.76114682
6TESK13.17903166
7ICK2.69707990
8BMPR1B2.43425335
9MAP4K22.38422655
10WNK42.27858728
11STK392.26775136
12MST42.16423712
13PTK2B1.99652007
14NTRK31.94421158
15ADRBK21.91782112
16LMTK21.90207026
17MAP3K41.86809138
18INSRR1.82501570
19GRK11.76595460
20EPHA41.76276983
21MAP3K121.72128187
22ACVR1B1.61804230
23FGFR21.61110144
24WNK11.59352974
25PHKG11.49016866
26PHKG21.49016866
27TNIK1.47865983
28STK381.47318321
29MAPK151.37582231
30MAP2K71.33639027
31PRKCE1.18363005
32MINK11.13343763
33TAOK31.10813620
34CAMK1G1.02443952
35CAMKK11.02238311
36MARK11.00740870
37NEK20.99904224
38TLK10.99134705
39TYRO30.98804626
40PAK60.98113597
41CSNK1G10.95219935
42PLK20.91569682
43BCR0.91395919
44AKT30.90098891
45NTRK20.88014721
46CAMKK20.87574696
47CCNB10.86560369
48MKNK20.85007364
49MAP2K60.84939629
50ADRBK10.83467911
51NME10.82404605
52EPHA30.81765066
53PRKCG0.81653800
54ZAK0.80834654
55PDK10.80519958
56MAPKAPK30.80202387
57CSNK1G30.80105597
58NUAK10.77438595
59DAPK20.71874411
60OXSR10.71373244
61STK38L0.71353864
62CDC70.70939495
63ERBB30.69703139
64STK30.69300930
65WNK30.68053483
66PASK0.66788943
67CAMK2B0.64170460
68TIE10.63811421
69DYRK20.60927298
70TTK0.60466068
71PINK10.60445785
72PRKG10.59991633
73NTRK10.58054436
74CSNK1A1L0.57844205
75STK110.56541557
76MAPKAPK50.56364283
77TRPM70.54534796
78CHEK20.54103655
79MAP3K90.54073008
80CDK50.53869153
81MAP2K40.53376752
82RIPK40.52815738
83PRKACA0.52804575
84CAMK2A0.51661594
85NLK0.50066674
86CHEK10.49695647
87SGK2230.48894618
88SGK4940.48894618
89SIK20.48784526
90MUSK0.48723582
91CDK30.48324764
92STK160.48042673
93NEK60.47687716
94PKN10.47337116
95CASK0.47242604
96DYRK1B0.45775232
97PDPK10.44081992
98CSNK1A10.43936468
99TRIM280.43933048
100CAMK2D0.43746027
101PRKCI0.43566091
102BMPR20.43277355
103MARK20.40481632
104PRKCA0.40420882
105PRKCQ0.40374694
106FRK0.40230110
107SGK20.40139157
108ATM0.39779336
109STK240.39304868
110MAPK100.38778851
111DAPK10.38472283
112PLK30.37942635
113PRKAA10.36974172
114MAPK130.36721199
115FER0.36090156
116RPS6KB10.35209165
117DYRK1A0.35070593
118BRSK20.34771375
119ERBB20.33916131
120MAP3K20.33794289
121PAK30.33790744
122TNK20.33302108
123CDK190.32666711
124BRSK10.32491048
125PIK3CA0.32485596
126PLK40.32432574
127UHMK10.32310182
128IRAK10.32196959
129TGFBR10.32094031
130PRKG20.31334438
131KSR10.31023994
132SGK10.30317325
133CSNK1E0.29760155
134RIPK10.28414027
135GSK3B0.28370603
136CSNK1G20.28014369
137PRKDC0.27335159
138CDK180.26791408
139BRAF0.26619602
140CDK150.26206408
141CDK140.25361273
142LATS20.25058759
143CAMK2G0.24309525
144RPS6KA30.24270331
145SGK30.23860645
146PRKCZ0.23365239
147MARK30.23117037
148GRK50.22915924
149CAMK10.22080758

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.59926640
2Amphetamine addiction_Homo sapiens_hsa050312.83505982
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.63425344
4Long-term potentiation_Homo sapiens_hsa047202.53484928
5Nicotine addiction_Homo sapiens_hsa050332.38239274
6Circadian entrainment_Homo sapiens_hsa047132.32325989
7Phototransduction_Homo sapiens_hsa047442.26170635
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.18547813
9Synaptic vesicle cycle_Homo sapiens_hsa047212.17224967
10Dorso-ventral axis formation_Homo sapiens_hsa043202.15955857
11Insulin secretion_Homo sapiens_hsa049112.14105463
12Taste transduction_Homo sapiens_hsa047422.09010237
13Butanoate metabolism_Homo sapiens_hsa006502.08901288
14Renin secretion_Homo sapiens_hsa049242.05154270
15Oocyte meiosis_Homo sapiens_hsa041142.03671880
16Glutamatergic synapse_Homo sapiens_hsa047241.99915333
17Morphine addiction_Homo sapiens_hsa050321.99613253
18Glucagon signaling pathway_Homo sapiens_hsa049221.97774367
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.93682770
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.92925774
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.92124349
22Protein export_Homo sapiens_hsa030601.88162578
23Dopaminergic synapse_Homo sapiens_hsa047281.86781238
24Salivary secretion_Homo sapiens_hsa049701.81927699
25Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.79609700
26Oxidative phosphorylation_Homo sapiens_hsa001901.79453030
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.76823860
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.73761310
29GABAergic synapse_Homo sapiens_hsa047271.71588250
30Nitrogen metabolism_Homo sapiens_hsa009101.68161518
31Gastric acid secretion_Homo sapiens_hsa049711.66209016
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.63224905
33Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.58071997
34Chemical carcinogenesis_Homo sapiens_hsa052041.56441016
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.50426911
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49283981
37Pyruvate metabolism_Homo sapiens_hsa006201.47239806
38Basal transcription factors_Homo sapiens_hsa030221.45830516
39Calcium signaling pathway_Homo sapiens_hsa040201.44875985
40Histidine metabolism_Homo sapiens_hsa003401.42049182
41Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40582545
42Cocaine addiction_Homo sapiens_hsa050301.38150604
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.36070830
44Oxytocin signaling pathway_Homo sapiens_hsa049211.32213277
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.31877278
46Estrogen signaling pathway_Homo sapiens_hsa049151.31653362
47beta-Alanine metabolism_Homo sapiens_hsa004101.31014032
48Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.30902953
49Cholinergic synapse_Homo sapiens_hsa047251.29034611
50Fatty acid biosynthesis_Homo sapiens_hsa000611.28696222
51cAMP signaling pathway_Homo sapiens_hsa040241.28695181
52Caffeine metabolism_Homo sapiens_hsa002321.28235811
53ABC transporters_Homo sapiens_hsa020101.28065669
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.26601097
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.25735167
56Phosphatidylinositol signaling system_Homo sapiens_hsa040701.25289965
57Cardiac muscle contraction_Homo sapiens_hsa042601.23673282
58Parkinsons disease_Homo sapiens_hsa050121.23018606
59Tryptophan metabolism_Homo sapiens_hsa003801.22620327
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.22463294
61Carbohydrate digestion and absorption_Homo sapiens_hsa049731.19062057
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.15272921
63Collecting duct acid secretion_Homo sapiens_hsa049661.13299373
64Thyroid hormone synthesis_Homo sapiens_hsa049181.12398691
65Vitamin B6 metabolism_Homo sapiens_hsa007501.12250550
66Selenocompound metabolism_Homo sapiens_hsa004501.12223724
67Peroxisome_Homo sapiens_hsa041461.11342955
68Serotonergic synapse_Homo sapiens_hsa047261.10886848
69Huntingtons disease_Homo sapiens_hsa050161.09370435
70Alzheimers disease_Homo sapiens_hsa050101.06573504
71mRNA surveillance pathway_Homo sapiens_hsa030151.04391435
72Retinol metabolism_Homo sapiens_hsa008301.03761946
73Long-term depression_Homo sapiens_hsa047301.03582135
74Vibrio cholerae infection_Homo sapiens_hsa051101.01455411
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.01428555
76Vascular smooth muscle contraction_Homo sapiens_hsa042701.00272445
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98566665
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94923649
79Gap junction_Homo sapiens_hsa045400.92920081
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.92294529
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.90541391
82Hedgehog signaling pathway_Homo sapiens_hsa043400.89047682
83Pancreatic secretion_Homo sapiens_hsa049720.88746292
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.88624739
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.88227737
86Type II diabetes mellitus_Homo sapiens_hsa049300.88036795
87Melanogenesis_Homo sapiens_hsa049160.87239776
88Sulfur metabolism_Homo sapiens_hsa009200.86354954
89Regulation of autophagy_Homo sapiens_hsa041400.85982215
90Folate biosynthesis_Homo sapiens_hsa007900.84531899
91Steroid hormone biosynthesis_Homo sapiens_hsa001400.83938242
92Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.83534037
93Tyrosine metabolism_Homo sapiens_hsa003500.76642787
94GnRH signaling pathway_Homo sapiens_hsa049120.74528748
95Propanoate metabolism_Homo sapiens_hsa006400.72499368
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72488277
97Inositol phosphate metabolism_Homo sapiens_hsa005620.71922596
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.71832529
99Alcoholism_Homo sapiens_hsa050340.71808458
100Wnt signaling pathway_Homo sapiens_hsa043100.70281419
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.69196194
102Mineral absorption_Homo sapiens_hsa049780.69108996
103Axon guidance_Homo sapiens_hsa043600.68490355
104Arachidonic acid metabolism_Homo sapiens_hsa005900.64188387
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63650649
106Glycerolipid metabolism_Homo sapiens_hsa005610.61391502
107Glioma_Homo sapiens_hsa052140.60803289
108Fatty acid degradation_Homo sapiens_hsa000710.58872502
109Glycerophospholipid metabolism_Homo sapiens_hsa005640.58805541
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58259851
111Ovarian steroidogenesis_Homo sapiens_hsa049130.57847187
112Sphingolipid metabolism_Homo sapiens_hsa006000.55720074
113mTOR signaling pathway_Homo sapiens_hsa041500.53550204
114Glutathione metabolism_Homo sapiens_hsa004800.52928481
115Fanconi anemia pathway_Homo sapiens_hsa034600.51654945
116MAPK signaling pathway_Homo sapiens_hsa040100.51615351
117Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50808084
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50616871
119Phenylalanine metabolism_Homo sapiens_hsa003600.49603389
120Tight junction_Homo sapiens_hsa045300.49089278
121Metabolic pathways_Homo sapiens_hsa011000.48748225
122Bile secretion_Homo sapiens_hsa049760.48486929
123Purine metabolism_Homo sapiens_hsa002300.48227602
124Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46566963
125Dilated cardiomyopathy_Homo sapiens_hsa054140.45436155
126Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44596446
127Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43298007
128ErbB signaling pathway_Homo sapiens_hsa040120.43105344
129AMPK signaling pathway_Homo sapiens_hsa041520.43073751
130alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41475670
131Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41329849
132RNA transport_Homo sapiens_hsa030130.40194931
133Circadian rhythm_Homo sapiens_hsa047100.39988330
134VEGF signaling pathway_Homo sapiens_hsa043700.39239653
135Linoleic acid metabolism_Homo sapiens_hsa005910.39216222
136Phospholipase D signaling pathway_Homo sapiens_hsa040720.38205002
137Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.37079938
138Endocytosis_Homo sapiens_hsa041440.35916012
139Insulin signaling pathway_Homo sapiens_hsa049100.33301383
140Ether lipid metabolism_Homo sapiens_hsa005650.33092467
141Central carbon metabolism in cancer_Homo sapiens_hsa052300.32747629
142Protein digestion and absorption_Homo sapiens_hsa049740.31238430
143Hippo signaling pathway_Homo sapiens_hsa043900.30386208
144Ras signaling pathway_Homo sapiens_hsa040140.29540135

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