CEBPE

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1leukocyte migration involved in inflammatory response (GO:0002523)8.82598507
2leukocyte aggregation (GO:0070486)8.60756621
3response to fungus (GO:0009620)8.40623934
4disruption of cells of other organism (GO:0044364)7.75770451
5killing of cells of other organism (GO:0031640)7.75770451
6sequestering of metal ion (GO:0051238)7.30364996
7neutrophil mediated immunity (GO:0002446)6.86713716
8response to peptidoglycan (GO:0032494)6.78321500
9respiratory burst (GO:0045730)6.20490504
10pentose-phosphate shunt (GO:0006098)5.67206016
11negative regulation of growth of symbiont in host (GO:0044130)5.47460804
12negative regulation of growth of symbiont involved in interaction with host (GO:0044146)5.47460804
13modulation of growth of symbiont involved in interaction with host (GO:0044144)5.47460804
14regulation of growth of symbiont in host (GO:0044126)5.47460804
15negative regulation of phagocytosis (GO:0050765)5.45712046
16reactive oxygen species biosynthetic process (GO:1903409)5.36433592
17myeloid leukocyte mediated immunity (GO:0002444)5.27264833
18NADPH regeneration (GO:0006740)5.19644066
19neutrophil activation involved in immune response (GO:0002283)5.08320634
20negative regulation of interleukin-8 production (GO:0032717)5.05689584
21positive regulation of gamma-delta T cell activation (GO:0046645)4.96551402
22microglial cell activation (GO:0001774)4.82890467
23positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.73496214
24cellular extravasation (GO:0045123)4.66927755
25chronic inflammatory response (GO:0002544)4.60231238
26Arp2/3 complex-mediated actin nucleation (GO:0034314)4.42769631
27hydrogen peroxide biosynthetic process (GO:0050665)4.33674749
28cell killing (GO:0001906)4.21945871
29negative regulation of erythrocyte differentiation (GO:0045647)4.19400629
30neutrophil activation (GO:0042119)4.15880644
31superoxide anion generation (GO:0042554)4.11805592
32positive regulation by symbiont of host defense response (GO:0052509)4.09460218
33modulation by symbiont of host defense response (GO:0052031)4.09460218
34modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.09460218
35modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.09460218
36positive regulation by organism of defense response of other organism involved in symbiotic interact4.09460218
37modulation by symbiont of host immune response (GO:0052553)4.09460218
38leukocyte mediated cytotoxicity (GO:0001909)4.08119701
39regulation of chemokine biosynthetic process (GO:0045073)4.06201264
40leukotriene biosynthetic process (GO:0019370)4.00716343
41antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.99124508
42leukotriene metabolic process (GO:0006691)3.97445487
43detection of bacterium (GO:0016045)3.97229235
44positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.95829370
45production of molecular mediator involved in inflammatory response (GO:0002532)3.91197577
46pentose metabolic process (GO:0019321)3.91006012
47detection of external biotic stimulus (GO:0098581)3.88023535
48macrophage activation involved in immune response (GO:0002281)3.84003433
49glucose catabolic process (GO:0006007)3.83495027
50detection of other organism (GO:0098543)3.78305002
51macrophage activation (GO:0042116)3.76744868
52neutrophil chemotaxis (GO:0030593)3.76593383
53granulocyte activation (GO:0036230)3.75553799
54neutrophil migration (GO:1990266)3.66081071
55regulation of myeloid leukocyte mediated immunity (GO:0002886)3.64422791
56negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.52489563
57detection of biotic stimulus (GO:0009595)3.46209019
58regulation of leukocyte degranulation (GO:0043300)3.44616740
59regulation of MHC class II biosynthetic process (GO:0045346)3.40559469
60negative regulation of interleukin-6 production (GO:0032715)3.37654040
61myeloid cell activation involved in immune response (GO:0002275)3.35346419
62regulation of gamma-delta T cell activation (GO:0046643)3.34800363
63negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.34726637
64negative regulation of cell killing (GO:0031342)3.34726637
65granulocyte migration (GO:0097530)3.29640800
66oxygen transport (GO:0015671)3.25661093
67phagosome maturation (GO:0090382)3.18634325
68negative regulation of lymphocyte mediated immunity (GO:0002707)3.17629121
69regulation of mast cell activation (GO:0033003)3.16008316
70actin nucleation (GO:0045010)3.15301335
71NADP metabolic process (GO:0006739)3.14160050
72interaction with symbiont (GO:0051702)3.13162495
73glucose 6-phosphate metabolic process (GO:0051156)3.12228358
74granulocyte chemotaxis (GO:0071621)3.11912312
75regulation of mast cell degranulation (GO:0043304)3.09625489
76positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.08234131
77regulation of gamma-delta T cell differentiation (GO:0045586)3.06087343
78regulation of regulated secretory pathway (GO:1903305)3.05597824
79positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.05168659
80modification by host of symbiont morphology or physiology (GO:0051851)3.05141537
81regulation of B cell receptor signaling pathway (GO:0050855)3.03874777
82leukocyte cell-cell adhesion (GO:0007159)3.02877331
83B cell receptor signaling pathway (GO:0050853)2.99415818
84regulation of tolerance induction (GO:0002643)2.99146328
85regulation of interferon-beta biosynthetic process (GO:0045357)2.96095938
86antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.94718856
87antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.94718856
88response to muramyl dipeptide (GO:0032495)2.93755726
89positive regulation of mast cell activation (GO:0033005)2.92581705
90response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.91765802
91response to host immune response (GO:0052572)2.91765802
92mannose metabolic process (GO:0006013)2.91272640
93innate immune response in mucosa (GO:0002227)2.89771560
94regulation of mast cell activation involved in immune response (GO:0033006)2.89418798
95lipopolysaccharide-mediated signaling pathway (GO:0031663)2.88277655
96detection of molecule of bacterial origin (GO:0032490)2.87955296
97cellular response to zinc ion (GO:0071294)2.86087899
98negative regulation of leukocyte mediated immunity (GO:0002704)2.85859825
99defense response to Gram-positive bacterium (GO:0050830)2.85214455
100positive regulation of chemokine biosynthetic process (GO:0045080)2.85048080
101positive regulation of lamellipodium assembly (GO:0010592)2.85032588
102positive regulation of B cell differentiation (GO:0045579)2.84452772
103positive regulation of regulated secretory pathway (GO:1903307)2.81103834
104regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.78684240
105antibacterial humoral response (GO:0019731)2.77396259
106nucleobase-containing small molecule interconversion (GO:0015949)2.77379450
107imidazole-containing compound metabolic process (GO:0052803)2.75560928
108antimicrobial humoral response (GO:0019730)2.73610020
109response to zinc ion (GO:0010043)2.73071160
110negative regulation of interleukin-12 production (GO:0032695)2.70878983
111* macrophage differentiation (GO:0030225)2.68897643
112regulation of phagocytosis (GO:0050764)2.66436326
113positive regulation of mast cell degranulation (GO:0043306)2.64464203
114positive regulation of mast cell activation involved in immune response (GO:0033008)2.64464203
1153-UTR-mediated mRNA stabilization (GO:0070935)2.62360063
116leukocyte degranulation (GO:0043299)2.59870080
117response to host (GO:0075136)2.59773104
118response to host defenses (GO:0052200)2.59773104
119response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.59773104
120mucosal immune response (GO:0002385)2.58171532
121regulation of hypersensitivity (GO:0002883)2.58055341
122regulation of interleukin-8 biosynthetic process (GO:0045414)2.57963383
123hydrogen peroxide metabolic process (GO:0042743)2.57781818
124DNA unwinding involved in DNA replication (GO:0006268)2.51692881
125immunoglobulin mediated immune response (GO:0016064)2.51508896
126regulation of B cell differentiation (GO:0045577)2.46572823
127* defense response to bacterium (GO:0042742)2.45592269
128negative regulation of myeloid cell apoptotic process (GO:0033033)2.45261171
129organ or tissue specific immune response (GO:0002251)2.43068806
130antigen processing and presentation of endogenous antigen (GO:0019883)2.42233056
131lipoxygenase pathway (GO:0019372)2.42131674
132homotypic cell-cell adhesion (GO:0034109)2.40784683
133disruption of cells of other organism involved in symbiotic interaction (GO:0051818)10.1064993
134killing of cells in other organism involved in symbiotic interaction (GO:0051883)10.1064993
135defense response to fungus (GO:0050832)10.0379074

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.64251079
2MYB_21317192_ChIP-Seq_ERMYB_Mouse4.26537380
3MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.75122639
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.57916915
5VDR_21846776_ChIP-Seq_THP-1_Human3.34083577
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.29833098
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.01435077
8NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.89666389
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.87514891
10BRD4_27068464_Chip-Seq_AML-cells_Mouse2.80697802
11BP1_19119308_ChIP-ChIP_Hs578T_Human2.58741949
12* SPI1_23547873_ChIP-Seq_NB4_Human2.55333072
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.50056031
14* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.46774413
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.44270892
16* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.42510156
17SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40458677
18VDR_24763502_ChIP-Seq_THP-1_Human2.34106125
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.33229163
20MYC_22102868_ChIP-Seq_BL_Human2.29138977
21* SCL_19346495_ChIP-Seq_HPC-7_Human2.26210461
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.16997006
23IRF8_27001747_Chip-Seq_BMDM_Mouse2.08940135
24RUNX1_22412390_ChIP-Seq_EML_Mouse2.04197367
25STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.01171164
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.96545067
27ELF1_17652178_ChIP-ChIP_JURKAT_Human1.96442008
28IRF8_22096565_ChIP-ChIP_GC-B_Human1.91938350
29UTX_26944678_Chip-Seq_JUKART_Human1.88428359
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86851511
31KDM2B_26808549_Chip-Seq_SUP-B15_Human1.85912796
32ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.84796891
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.79113977
34KDM2B_26808549_Chip-Seq_DND41_Human1.75705276
35MAF_26560356_Chip-Seq_TH1_Human1.75330163
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.74455104
37MYB_26560356_Chip-Seq_TH2_Human1.72855576
38* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69474681
39SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.69411516
40ESR1_15608294_ChIP-ChIP_MCF-7_Human1.67959449
41* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.65049703
42STAT4_19710469_ChIP-ChIP_TH1__Mouse1.56902046
43* TCF7_22412390_ChIP-Seq_EML_Mouse1.54766975
44CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.54394933
45MYB_26560356_Chip-Seq_TH1_Human1.53619571
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.53354861
47* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.52596912
48SPI1_23127762_ChIP-Seq_K562_Human1.51276670
49* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.50904779
50RUNX_20019798_ChIP-Seq_JUKART_Human1.49272369
51STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.47927801
52PPARA_22158963_ChIP-Seq_LIVER_Mouse1.46444457
53CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.44261559
54VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43515016
55* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.42723483
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39551107
57* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38879827
58* BCOR_27268052_Chip-Seq_Bcells_Human1.38794420
59RXR_22158963_ChIP-Seq_LIVER_Mouse1.38292452
60E2F1_21310950_ChIP-Seq_MCF-7_Human1.37325208
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.36437274
62AR_21909140_ChIP-Seq_LNCAP_Human1.36111523
63* GATA1_19941826_ChIP-Seq_K562_Human1.33527134
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.32695320
65STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.32177716
66VDR_24787735_ChIP-Seq_THP-1_Human1.32056833
67E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30908575
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29935740
69PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.28264123
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27901877
71PU.1_20513432_ChIP-Seq_Bcells_Mouse1.27074405
72TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25692344
73* PU_27001747_Chip-Seq_BMDM_Mouse1.25138063
74IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.24375733
75P68_20966046_ChIP-Seq_HELA_Human1.23229669
76FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22872778
77MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.22451398
78Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.21973162
79ELF1_20517297_ChIP-Seq_JURKAT_Human1.20887210
80FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.20743908
81* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20274799
82CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19593689
83GATA1_22025678_ChIP-Seq_K562_Human1.18654342
84EGR1_23403033_ChIP-Seq_LIVER_Mouse1.18547770
85TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.18381249
86* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.17899959
87* NCOR1_26117541_ChIP-Seq_K562_Human1.16948942
88* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15318774
89RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15245997
90GATA1_19941827_ChIP-Seq_MEL_Mouse1.13882069
91MAF_26560356_Chip-Seq_TH2_Human1.13873715
92NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.13372680
93MYC_18555785_ChIP-Seq_MESCs_Mouse1.10010706
94SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08617293
95* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.08251250
96* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07523897
97SA1_27219007_Chip-Seq_ERYTHROID_Human1.06290915
98STAT6_21828071_ChIP-Seq_BEAS2B_Human1.05607356
99* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05565932
100MYC_18358816_ChIP-ChIP_MESCs_Mouse1.05081542
101TFEB_21752829_ChIP-Seq_HELA_Human1.04443153
102RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.03240086
103FOXP3_21729870_ChIP-Seq_TREG_Human1.01808115
104* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01369659
105KDM2B_26808549_Chip-Seq_JURKAT_Human1.00660522
106CREB1_15753290_ChIP-ChIP_HEK293T_Human0.98561525
107* GATA2_19941826_ChIP-Seq_K562_Human0.98521547
108EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96781388
109* BCL6_27268052_Chip-Seq_Bcells_Human0.96140218
110SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95657028
111GATA3_27048872_Chip-Seq_THYMUS_Human0.95464816
112E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94448637
113* ELK3_25401928_ChIP-Seq_HUVEC_Human0.94301763
114EST1_17652178_ChIP-ChIP_JURKAT_Human0.93873204
115XRN2_22483619_ChIP-Seq_HELA_Human0.93783955
116FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.93522259
117CIITA_25753668_ChIP-Seq_RAJI_Human0.93233493
118GATA3_26560356_Chip-Seq_TH2_Human0.91368357
119* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91254431
120LXR_22292898_ChIP-Seq_THP-1_Human0.90619529
121PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90152877
122* SPI1_20517297_ChIP-Seq_HL60_Human0.89850641
123KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.87570887

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003436_decreased_susceptibility_to4.63876936
2MP0009785_altered_susceptibility_to3.69722540
3MP0003183_abnormal_peptide_metabolism3.69698777
4* MP0002419_abnormal_innate_immunity3.34249056
5MP0005464_abnormal_platelet_physiology3.14983863
6* MP0005025_abnormal_response_to2.67979816
7* MP0003303_peritoneal_inflammation2.36336824
8MP0002396_abnormal_hematopoietic_system2.36307423
9MP0000465_gastrointestinal_hemorrhage2.36272025
10MP0001835_abnormal_antigen_presentation2.28938812
11MP0003693_abnormal_embryo_hatching2.28817711
12MP0005000_abnormal_immune_tolerance2.14302539
13MP0003656_abnormal_erythrocyte_physiolo2.13663598
14MP0009278_abnormal_bone_marrow2.11420043
15MP0003300_gastrointestinal_ulcer2.09429109
16MP0005397_hematopoietic_system_phenotyp2.05983053
17MP0001545_abnormal_hematopoietic_system2.05983053
18* MP0002420_abnormal_adaptive_immunity2.03159829
19MP0001853_heart_inflammation2.02516240
20* MP0001819_abnormal_immune_cell2.01143253
21MP0002148_abnormal_hypersensitivity_rea1.99456722
22MP0000685_abnormal_immune_system1.99100997
23MP0002452_abnormal_antigen_presenting1.98452464
24MP0003172_abnormal_lysosome_physiology1.97404241
25MP0003191_abnormal_cellular_cholesterol1.92271995
26MP0000343_altered_response_to1.92038136
27MP0004808_abnormal_hematopoietic_stem1.91786107
28MP0001800_abnormal_humoral_immune1.90765070
29* MP0001533_abnormal_skeleton_physiology1.88951899
30MP0004147_increased_porphyrin_level1.86176976
31* MP0001845_abnormal_inflammatory_respons1.84381035
32MP0003724_increased_susceptibility_to1.84177491
33MP0002723_abnormal_immune_serum1.84169730
34MP0008260_abnormal_autophagy1.77476324
35* MP0002398_abnormal_bone_marrow1.76835789
36* MP0002405_respiratory_system_inflammati1.76740578
37MP0005360_urolithiasis1.73577580
38MP0002132_abnormal_respiratory_system1.73568041
39MP0009840_abnormal_foam_cell1.72803766
40MP0003806_abnormal_nucleotide_metabolis1.69542756
41* MP0000716_abnormal_immune_system1.65828883
42MP0005058_abnormal_lysosome_morphology1.62830336
43MP0000858_altered_metastatic_potential1.57798138
44MP0008469_abnormal_protein_level1.57554083
45MP0003828_pulmonary_edema1.55307280
46MP0004185_abnormal_adipocyte_glucose1.53881369
47MP0000689_abnormal_spleen_morphology1.52592430
48MP0002166_altered_tumor_susceptibility1.52494711
49* MP0002429_abnormal_blood_cell1.52300780
50MP0005451_abnormal_body_composition1.51187547
51MP0005671_abnormal_response_to1.50609717
52MP0001790_abnormal_immune_system1.48938235
53MP0005387_immune_system_phenotype1.48938235
54MP0000015_abnormal_ear_pigmentation1.47438968
55MP0010307_abnormal_tumor_latency1.47331006
56* MP0002722_abnormal_immune_system1.46680189
57MP0010094_abnormal_chromosome_stability1.43059377
58MP0002139_abnormal_hepatobiliary_system1.41209941
59MP0003111_abnormal_nucleus_morphology1.40721011
60MP0005174_abnormal_tail_pigmentation1.40235066
61MP0000490_abnormal_crypts_of1.36898090
62MP0003075_altered_response_to1.36175972
63MP0005075_abnormal_melanosome_morpholog1.31801972
64MP0009764_decreased_sensitivity_to1.27454857
65MP0010329_abnormal_lipoprotein_level1.26799157
66MP0001873_stomach_inflammation1.26396740
67MP0003186_abnormal_redox_activity1.25910705
68MP0001764_abnormal_homeostasis1.25546569
69MP0005365_abnormal_bile_salt1.24737747
70MP0003566_abnormal_cell_adhesion1.23574285
71MP0008057_abnormal_DNA_replication1.21874458
72* MP0010155_abnormal_intestine_physiology1.20853899
73MP0005085_abnormal_gallbladder_physiolo1.17231990
74MP0009763_increased_sensitivity_to1.13846458
75MP0005023_abnormal_wound_healing1.13784141
76MP0005076_abnormal_cell_differentiation1.12969025
77MP0002006_tumorigenesis1.11299511
78MP0009333_abnormal_splenocyte_physiolog1.08141958
79MP0003077_abnormal_cell_cycle1.08124308
80MP0005310_abnormal_salivary_gland1.07099691
81MP0004947_skin_inflammation1.04401867
82MP0008875_abnormal_xenobiotic_pharmacok1.00026468
83MP0002019_abnormal_tumor_incidence0.99845688
84MP0005083_abnormal_biliary_tract0.98639610
85MP0002998_abnormal_bone_remodeling0.97796784
86MP0005319_abnormal_enzyme/_coenzyme0.97674746
87MP0004883_abnormal_blood_vessel0.97272904
88MP0000609_abnormal_liver_physiology0.96743539
89MP0002009_preneoplasia0.96534549
90MP0000703_abnormal_thymus_morphology0.96443411
91MP0004381_abnormal_hair_follicle0.94511821
92MP0004957_abnormal_blastocyst_morpholog0.94110820
93MP0001986_abnormal_taste_sensitivity0.92055932
94* MP0001851_eye_inflammation0.91714007
95MP0002933_joint_inflammation0.91397920
96MP0003448_altered_tumor_morphology0.88967103
97MP0004130_abnormal_muscle_cell0.88895513
98MP0005164_abnormal_response_to0.87531943
99MP0002837_dystrophic_cardiac_calcinosis0.86926313
100MP0002877_abnormal_melanocyte_morpholog0.85932311
101MP0002277_abnormal_respiratory_mucosa0.85023303
102MP0003221_abnormal_cardiomyocyte_apopto0.81463683
103MP0003763_abnormal_thymus_physiology0.81176527
104MP0000598_abnormal_liver_morphology0.80814387
105MP0005584_abnormal_enzyme/coenzyme_acti0.80190069
106MP0008873_increased_physiological_sensi0.78520671
107* MP0005390_skeleton_phenotype0.77398851
108MP0005166_decreased_susceptibility_to0.76844664
109MP0005167_abnormal_blood-brain_barrier0.76717605
110MP0000249_abnormal_blood_vessel0.76564461
111MP0003866_abnormal_defecation0.75722691
112MP0002089_abnormal_postnatal_growth/wei0.75477651
113MP0009765_abnormal_xenobiotic_induced0.72842959
114MP0010352_gastrointestinal_tract_polyps0.71901576
115MP0003123_paternal_imprinting0.71561640
116MP0006082_CNS_inflammation0.69944178
117MP0000313_abnormal_cell_death0.69202805
118MP0000604_amyloidosis0.68623386
119MP0008874_decreased_physiological_sensi0.67744509
120* MP0001663_abnormal_digestive_system0.63558597
121MP0003690_abnormal_glial_cell0.63471727
122MP0006036_abnormal_mitochondrial_physio0.61406570
123MP0005666_abnormal_adipose_tissue0.61224320
124* MP0003795_abnormal_bone_structure0.60501887
125MP0005376_homeostasis/metabolism_phenot0.58010314
126MP0006035_abnormal_mitochondrial_morpho0.55111066

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)8.53147117
2Recurrent abscess formation (HP:0002722)8.12449182
3Recurrent gram-negative bacterial infections (HP:0005420)7.95427197
4Recurrent bacterial skin infections (HP:0005406)7.31878456
5Chronic obstructive pulmonary disease (HP:0006510)6.02634971
6Obstructive lung disease (HP:0006536)6.02634971
7Hypochromic microcytic anemia (HP:0004840)5.03061805
8Mediastinal lymphadenopathy (HP:0100721)4.85888908
9Abnormality of macrophages (HP:0004311)4.85633828
10Recurrent skin infections (HP:0001581)4.55698618
11Gingivitis (HP:0000230)4.55561623
12Recurrent fungal infections (HP:0002841)4.33658834
13Cellulitis (HP:0100658)4.06378217
14Urticaria (HP:0001025)3.98564062
15Abnormality of the heme biosynthetic pathway (HP:0010472)3.90467015
16Meningitis (HP:0001287)3.88601719
17Thrombocytosis (HP:0001894)3.73182653
18Stomatitis (HP:0010280)3.68970967
19Increased cerebral lipofuscin (HP:0011813)3.42373643
20Papilledema (HP:0001085)3.40531153
21Loss of speech (HP:0002371)3.33166277
22Petechiae (HP:0000967)3.29186156
23Increased neuronal autofluorescent lipopigment (HP:0002074)3.25048930
24Retrobulbar optic neuritis (HP:0100654)3.23701314
25Optic neuritis (HP:0100653)3.23701314
26Microcytic anemia (HP:0001935)3.17400875
27Periodontitis (HP:0000704)3.12497482
28Myositis (HP:0100614)3.02914074
29Abnormal platelet volume (HP:0011876)2.99525467
30Chest pain (HP:0100749)2.85394869
31Panhypogammaglobulinemia (HP:0003139)2.83181076
32Keratoconjunctivitis sicca (HP:0001097)2.82899297
33IgM deficiency (HP:0002850)2.82677690
34Epistaxis (HP:0000421)2.82116928
35Abnormal platelet function (HP:0011869)2.78365549
36Impaired platelet aggregation (HP:0003540)2.78365549
37Abnormality of glycolipid metabolism (HP:0010969)2.77018584
38Abnormality of liposaccharide metabolism (HP:0010968)2.77018584
39Abnormality of glycosphingolipid metabolism (HP:0004343)2.77018584
40Osteomyelitis (HP:0002754)2.76387861
41Vacuolated lymphocytes (HP:0001922)2.75572391
42Recurrent cutaneous fungal infections (HP:0011370)2.75206293
43Chronic mucocutaneous candidiasis (HP:0002728)2.75206293
44Increased serum ferritin (HP:0003281)2.69314795
45Recurrent viral infections (HP:0004429)2.68894804
46Prolonged bleeding time (HP:0003010)2.61194224
47Chronic otitis media (HP:0000389)2.60310289
48Gingival bleeding (HP:0000225)2.56488964
49Keratoconjunctivitis (HP:0001096)2.56148732
50Abnormality of the prostate (HP:0008775)2.53332483
51Increased mean platelet volume (HP:0011877)2.52570559
52Elevated erythrocyte sedimentation rate (HP:0003565)2.51400263
53Sepsis (HP:0100806)2.50900441
54Eosinophilia (HP:0001880)2.50869650
55Granulocytopenia (HP:0001913)2.48155269
56Leukocytosis (HP:0001974)2.45368519
57Abnormality of mucopolysaccharide metabolism (HP:0011020)2.43483224
58Abnormality of polysaccharide metabolism (HP:0011012)2.43483224
59Abnormality of glycosaminoglycan metabolism (HP:0004371)2.43483224
60Hypergammaglobulinemia (HP:0010702)2.41390216
61Abnormal delayed hypersensitivity skin test (HP:0002963)2.39841574
62Agammaglobulinemia (HP:0004432)2.39211637
63Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.38223990
64Skin ulcer (HP:0200042)2.36798474
65Joint hemorrhage (HP:0005261)2.31164718
66Vasculitis (HP:0002633)2.29868758
67Thoracic kyphosis (HP:0002942)2.28785324
68Recurrent pneumonia (HP:0006532)2.28340321
69Hemoptysis (HP:0002105)2.28073441
70Abnormality of pyrimidine metabolism (HP:0004353)2.26749930
71Abnormality of T cell physiology (HP:0011840)2.25819487
72B lymphocytopenia (HP:0010976)2.22805789
73Abnormality of B cell number (HP:0010975)2.22805789
74Reticulocytopenia (HP:0001896)2.22464026
75Abnormality of the common coagulation pathway (HP:0010990)2.20769701
76Episodic fever (HP:0001954)2.20726263
77Abnormality of transition element cation homeostasis (HP:0011030)2.18585345
78Slow saccadic eye movements (HP:0000514)2.17403350
79Abnormality of the thoracic spine (HP:0100711)2.16277251
80Cutaneous melanoma (HP:0012056)2.13667722
81Menorrhagia (HP:0000132)2.13209625
82Deep venous thrombosis (HP:0002625)2.13041116
83Polycythemia (HP:0001901)2.11637399
84Amyloidosis (HP:0011034)2.11616032
85Abnormality of the fingertips (HP:0001211)2.10364828
86Interstitial pulmonary disease (HP:0006530)2.08062877
87Anorexia (HP:0002039)2.07391848
88Reduced antithrombin III activity (HP:0001976)2.06033095
89Acute lymphatic leukemia (HP:0006721)2.05823306
90Pulmonary embolism (HP:0002204)2.04783262
91Hypermelanotic macule (HP:0001034)2.03671097
92Neutropenia (HP:0001875)2.02925115
93Abnormality of T cells (HP:0002843)2.02699613
94Asymmetric septal hypertrophy (HP:0001670)2.02193117
95Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.01455636
96Thrombophlebitis (HP:0004418)2.01391597
97Pustule (HP:0200039)2.01360370
98Hypertriglyceridemia (HP:0002155)2.00860118
99Colitis (HP:0002583)2.00733404
100Disinhibition (HP:0000734)1.99895684
101Cutaneous photosensitivity (HP:0000992)1.98000450
102Hepatosplenomegaly (HP:0001433)1.96348050
103Spontaneous hematomas (HP:0007420)1.96027854
104Systemic lupus erythematosus (HP:0002725)1.95495377
105Hypochromic anemia (HP:0001931)1.94129676
106Gastrointestinal infarctions (HP:0005244)1.91504277
107Abnormality of the lumbar spine (HP:0100712)1.91480547
108Gangrene (HP:0100758)1.89875924
109Recurrent lower respiratory tract infections (HP:0002783)1.89363940
110Aplastic anemia (HP:0001915)1.88741954
111Myelodysplasia (HP:0002863)1.88410357
112Cheilitis (HP:0100825)1.86939334
113Dysostosis multiplex (HP:0000943)1.86614521
114Abnormality of eosinophils (HP:0001879)1.86595413
115Abnormality of cells of the lymphoid lineage (HP:0012140)1.83810039
116Purpura (HP:0000979)1.82882350
117Orchitis (HP:0100796)1.82613261
118Inflammation of the large intestine (HP:0002037)1.80424999
119Poikiloderma (HP:0001029)1.80424681
120Prolonged partial thromboplastin time (HP:0003645)1.79861165
121Gastrointestinal inflammation (HP:0004386)1.79704087
122Arterial thrombosis (HP:0004420)1.79132624
123Increased IgE level (HP:0003212)1.79106068
124Abnormality of the pleura (HP:0002103)1.77295361
125Lymphopenia (HP:0001888)1.75774341
126Encephalitis (HP:0002383)1.75389876
127Skin rash (HP:0000988)1.75269226
128Abnormal foot bone ossification (HP:0010675)1.71373680
129Abnormality of iron homeostasis (HP:0011031)1.70271104
130Autoimmune thrombocytopenia (HP:0001973)1.69999618
131Mucopolysacchariduria (HP:0008155)1.69638272
132Urinary glycosaminoglycan excretion (HP:0003541)1.69638272
133Increased density of long bones (HP:0006392)1.67817976
134Pulmonary infiltrates (HP:0002113)1.66411631

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK45.14653645
2TESK23.27350156
3BLK3.17980049
4FES2.86012703
5EPHB12.66539212
6GRK62.58860125
7ERN12.42873476
8BTK2.41157564
9MAP4K12.40486246
10PRPF4B2.35858433
11MAP2K32.26860157
12TESK12.25488499
13TRPM72.23212422
14RIPK42.21563660
15PKN22.08056599
16TAOK32.07470216
17MAP3K122.06404881
18WEE11.84887562
19TEC1.80132751
20TRIB31.76298139
21CLK11.72881308
22STK101.66623348
23CSK1.65530569
24CDK121.60447269
25EEF2K1.54831548
26NEK21.51022213
27PAK41.50008420
28TTN1.47792267
29ZAP701.46761161
30LRRK21.34395860
31SYK1.30381026
32HCK1.30253275
33CDC71.29531145
34TAOK21.29087761
35SMG11.28034418
36ERBB31.17619581
37MAP2K41.14465087
38MAP3K111.12150813
39STK161.11399843
40ALK1.10822142
41LIMK11.09880827
42TYK21.07557928
43PIM21.07427921
44PIM11.06064935
45KDR1.05945271
46TGFBR21.05346617
47LATS11.04532697
48MAP3K81.02601861
49IRAK21.01973256
50IRAK31.01323362
51CSF1R0.98463905
52CDK190.94493486
53EIF2AK30.92368495
54KIT0.91512731
55BRSK20.91358872
56CAMK1D0.91003121
57FGR0.90647767
58PTK60.90302405
59FLT30.89641029
60PDPK10.88507011
61PRKG20.88430276
62IRAK10.87427411
63TAOK10.86903978
64LYN0.86476200
65PDK10.84260414
66MAP3K60.83849923
67MAP3K130.81775766
68BUB10.78183942
69IKBKB0.77689197
70STK40.77597144
71YES10.76513770
72TBK10.75516722
73RPS6KC10.75146537
74RPS6KL10.75146537
75SIK20.73960916
76RPS6KA60.73758554
77ITK0.73312082
78SCYL20.73123401
79TXK0.69904671
80NUAK10.69444002
81MARK30.69334405
82JAK20.68711668
83MAP3K140.65193237
84PIK3CG0.65077433
85LCK0.64473574
86RPS6KA20.64121430
87TNK20.61945149
88BCKDK0.61835746
89CDK70.61686301
90RAF10.60926927
91TLK10.60303828
92CDK40.58624377
93ATR0.57374739
94MAP2K60.56567769
95DAPK10.55622100
96GRK70.54795793
97ILK0.54249426
98MATK0.52716599
99MAPK120.52514832
100* MAPK40.51906365
101PRKCD0.50368880
102MAP3K30.49958109
103MAP2K20.49899247
104HIPK20.48712211
105MAPK110.48694180
106MARK20.47013936
107STK110.44274319
108RPS6KB20.43592566
109PRKD20.42883864
110ARAF0.42355365
111MAPKAPK20.40865975
112ACVR1B0.40787632
113NEK90.40219827
114CAMK1G0.39891662
115KSR20.39395471
116MAP3K100.39192107
117NEK10.38850280
118PRKCQ0.38498292
119RPS6KA40.38276095
120IKBKE0.38246940
121CDK60.38145633
122RET0.37714571
123CAMKK20.36016346
124MAP3K50.35265503
125JAK30.32824550
126FYN0.32147764
127MAPKAPK30.31337662
128CDK30.31184499
129CCNB10.30808422
130JAK10.30212199
131RPS6KA10.30134576
132PAK10.29742315
133MYLK0.29450360
134MAP3K10.29193900
135BMX0.29184056
136MAPK70.28231030

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.19885987
2Leishmaniasis_Homo sapiens_hsa051403.53961939
3Pentose phosphate pathway_Homo sapiens_hsa000302.88283056
4Staphylococcus aureus infection_Homo sapiens_hsa051502.76956959
5DNA replication_Homo sapiens_hsa030302.74143739
6Asthma_Homo sapiens_hsa053102.50991390
7Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.27982811
8Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.02667017
9Leukocyte transendothelial migration_Homo sapiens_hsa046701.96971392
10Osteoclast differentiation_Homo sapiens_hsa043801.95750143
11Primary immunodeficiency_Homo sapiens_hsa053401.93794891
12Starch and sucrose metabolism_Homo sapiens_hsa005001.77364574
13Histidine metabolism_Homo sapiens_hsa003401.67231627
14Other glycan degradation_Homo sapiens_hsa005111.64781926
15Caffeine metabolism_Homo sapiens_hsa002321.62908160
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.59117607
17African trypanosomiasis_Homo sapiens_hsa051431.57347504
18Tuberculosis_Homo sapiens_hsa051521.52430631
19B cell receptor signaling pathway_Homo sapiens_hsa046621.47861146
20Graft-versus-host disease_Homo sapiens_hsa053321.46297367
21Pertussis_Homo sapiens_hsa051331.44925061
22Allograft rejection_Homo sapiens_hsa053301.42648939
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.42416506
24Glutathione metabolism_Homo sapiens_hsa004801.39015127
25Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.38480899
26Phagosome_Homo sapiens_hsa041451.37166081
27Legionellosis_Homo sapiens_hsa051341.36074964
28Primary bile acid biosynthesis_Homo sapiens_hsa001201.35596002
29Shigellosis_Homo sapiens_hsa051311.33611225
30T cell receptor signaling pathway_Homo sapiens_hsa046601.32860072
31One carbon pool by folate_Homo sapiens_hsa006701.30905062
32Autoimmune thyroid disease_Homo sapiens_hsa053201.29868233
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.25732350
34Complement and coagulation cascades_Homo sapiens_hsa046101.24906950
35Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.19870246
36Glycosaminoglycan degradation_Homo sapiens_hsa005311.18296909
37NOD-like receptor signaling pathway_Homo sapiens_hsa046211.16144746
38Platelet activation_Homo sapiens_hsa046111.14137118
39Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.13214211
40Drug metabolism - other enzymes_Homo sapiens_hsa009831.12548094
41Chemokine signaling pathway_Homo sapiens_hsa040621.08664949
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08060513
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.07894726
44Galactose metabolism_Homo sapiens_hsa000521.06888054
45Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.06695653
46Carbon metabolism_Homo sapiens_hsa012001.06322318
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01345153
48Sulfur relay system_Homo sapiens_hsa041221.01134224
49Biosynthesis of amino acids_Homo sapiens_hsa012301.01023302
50Mismatch repair_Homo sapiens_hsa034301.00877519
51Base excision repair_Homo sapiens_hsa034100.99737607
52Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97631471
53ABC transporters_Homo sapiens_hsa020100.96393891
54Acute myeloid leukemia_Homo sapiens_hsa052210.94528189
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93593076
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.93159860
57Intestinal immune network for IgA production_Homo sapiens_hsa046720.93032912
58Homologous recombination_Homo sapiens_hsa034400.92827881
59Hematopoietic cell lineage_Homo sapiens_hsa046400.90628372
60Cell cycle_Homo sapiens_hsa041100.89087073
61RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.87842761
62Type I diabetes mellitus_Homo sapiens_hsa049400.87834671
63Salmonella infection_Homo sapiens_hsa051320.87370324
64Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.86166790
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.84214029
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.83347367
67Adipocytokine signaling pathway_Homo sapiens_hsa049200.81710000
68Hepatitis C_Homo sapiens_hsa051600.81301245
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80860915
70Peroxisome_Homo sapiens_hsa041460.80126514
71Lysosome_Homo sapiens_hsa041420.75974149
72Toxoplasmosis_Homo sapiens_hsa051450.75268978
73Herpes simplex infection_Homo sapiens_hsa051680.74889869
74beta-Alanine metabolism_Homo sapiens_hsa004100.74511099
75Apoptosis_Homo sapiens_hsa042100.74273444
76Rheumatoid arthritis_Homo sapiens_hsa053230.73786784
77Arginine biosynthesis_Homo sapiens_hsa002200.72179786
78VEGF signaling pathway_Homo sapiens_hsa043700.71973324
79Hepatitis B_Homo sapiens_hsa051610.71780778
80Viral myocarditis_Homo sapiens_hsa054160.71747785
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.71107935
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.71064948
83Non-small cell lung cancer_Homo sapiens_hsa052230.69108017
84Viral carcinogenesis_Homo sapiens_hsa052030.68471597
85N-Glycan biosynthesis_Homo sapiens_hsa005100.68279402
86Fructose and mannose metabolism_Homo sapiens_hsa000510.67743350
87Notch signaling pathway_Homo sapiens_hsa043300.66422944
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65769068
89Ribosome_Homo sapiens_hsa030100.64493044
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.64434392
91Epstein-Barr virus infection_Homo sapiens_hsa051690.63899563
92Measles_Homo sapiens_hsa051620.62928759
93Regulation of autophagy_Homo sapiens_hsa041400.62312962
94Bladder cancer_Homo sapiens_hsa052190.61707989
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61265704
96Cyanoamino acid metabolism_Homo sapiens_hsa004600.61176608
97Systemic lupus erythematosus_Homo sapiens_hsa053220.60606531
98Selenocompound metabolism_Homo sapiens_hsa004500.60555217
99Pancreatic cancer_Homo sapiens_hsa052120.60503566
100Renal cell carcinoma_Homo sapiens_hsa052110.59786164
101Choline metabolism in cancer_Homo sapiens_hsa052310.58619807
102Chronic myeloid leukemia_Homo sapiens_hsa052200.57754439
103HTLV-I infection_Homo sapiens_hsa051660.57604885
104mTOR signaling pathway_Homo sapiens_hsa041500.57602648
105GnRH signaling pathway_Homo sapiens_hsa049120.57520707
106HIF-1 signaling pathway_Homo sapiens_hsa040660.56692207
107Insulin resistance_Homo sapiens_hsa049310.56225031
108Phenylalanine metabolism_Homo sapiens_hsa003600.55437917
109AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54908806
110* Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54647403
111Renin-angiotensin system_Homo sapiens_hsa046140.53972218
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53666591
113FoxO signaling pathway_Homo sapiens_hsa040680.51986938
114Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51726725
115Influenza A_Homo sapiens_hsa051640.50712481
116Malaria_Homo sapiens_hsa051440.50520919
117Colorectal cancer_Homo sapiens_hsa052100.49043848
118Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48972286
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48662831
120Prolactin signaling pathway_Homo sapiens_hsa049170.48332533
121Fatty acid degradation_Homo sapiens_hsa000710.47218301
122Antigen processing and presentation_Homo sapiens_hsa046120.47086664
123TNF signaling pathway_Homo sapiens_hsa046680.46726368
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46680669
125Tryptophan metabolism_Homo sapiens_hsa003800.46380044
126Jak-STAT signaling pathway_Homo sapiens_hsa046300.46372452
127p53 signaling pathway_Homo sapiens_hsa041150.46267024
128Phospholipase D signaling pathway_Homo sapiens_hsa040720.45394013
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44971879
130Fanconi anemia pathway_Homo sapiens_hsa034600.44251413
131Amoebiasis_Homo sapiens_hsa051460.43844347
132Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.43453879
133Cysteine and methionine metabolism_Homo sapiens_hsa002700.43072594
134Endocytosis_Homo sapiens_hsa041440.42438273
135Type II diabetes mellitus_Homo sapiens_hsa049300.42202217
136Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42167176
137Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42098847
138Nitrogen metabolism_Homo sapiens_hsa009100.41532982
139Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41138637
140Inositol phosphate metabolism_Homo sapiens_hsa005620.40099487
141Endometrial cancer_Homo sapiens_hsa052130.37616499

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