CDPF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.12801664
2ribosomal small subunit assembly (GO:0000028)5.71864799
3proteasome assembly (GO:0043248)5.44036969
4viral transcription (GO:0019083)4.85445304
5translational termination (GO:0006415)4.75466819
6base-excision repair, AP site formation (GO:0006285)4.69674993
7maturation of SSU-rRNA (GO:0030490)4.64439515
8ribosomal large subunit biogenesis (GO:0042273)4.55386119
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.54375197
10establishment of protein localization to mitochondrial membrane (GO:0090151)4.47406430
11mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.46149638
12cotranslational protein targeting to membrane (GO:0006613)4.45863248
13translational elongation (GO:0006414)4.42760861
14protein targeting to ER (GO:0045047)4.41550362
15ubiquinone biosynthetic process (GO:0006744)4.35103103
16ribosomal small subunit biogenesis (GO:0042274)4.32482558
17protein localization to endoplasmic reticulum (GO:0070972)4.20961578
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.19317721
19ATP synthesis coupled proton transport (GO:0015986)4.12883708
20energy coupled proton transport, down electrochemical gradient (GO:0015985)4.12883708
21nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.08945381
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.08656699
23ubiquinone metabolic process (GO:0006743)4.02906489
24oxidative phosphorylation (GO:0006119)4.02028030
25L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.99749153
26translational initiation (GO:0006413)3.95627868
27formation of translation preinitiation complex (GO:0001731)3.92259104
28translation (GO:0006412)3.91372864
29mannosylation (GO:0097502)3.90922651
30termination of RNA polymerase III transcription (GO:0006386)3.88866729
31transcription elongation from RNA polymerase III promoter (GO:0006385)3.88866729
32deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.82504007
33regulation of mitochondrial translation (GO:0070129)3.81078610
34viral life cycle (GO:0019058)3.80144527
35positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.78941155
36cellular protein complex disassembly (GO:0043624)3.75839671
37regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.75517099
38negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.74776124
39negative regulation of ligase activity (GO:0051352)3.74776124
40regulation of cellular amino acid metabolic process (GO:0006521)3.73334406
41telomere maintenance via semi-conservative replication (GO:0032201)3.70857649
42ribonucleoprotein complex biogenesis (GO:0022613)3.70636162
43protein deneddylation (GO:0000338)3.69018573
44pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.68015815
45negative regulation of telomere maintenance (GO:0032205)3.67233121
46anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.67116670
47DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.66305123
48GTP biosynthetic process (GO:0006183)3.66017668
49peptidyl-histidine modification (GO:0018202)3.64885997
50guanosine-containing compound biosynthetic process (GO:1901070)3.62770458
51antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.61313772
52pyrimidine nucleotide catabolic process (GO:0006244)3.61110690
53nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.60812028
54DNA strand elongation involved in DNA replication (GO:0006271)3.60749780
55intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.60355946
56signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.60355946
57deoxyribonucleotide catabolic process (GO:0009264)3.59796360
58signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.57573965
59signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.57573965
60signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.57573965
61platelet dense granule organization (GO:0060155)3.57439585
62pseudouridine synthesis (GO:0001522)3.56208636
63cullin deneddylation (GO:0010388)3.54513050
64respiratory chain complex IV assembly (GO:0008535)3.48849597
65inner mitochondrial membrane organization (GO:0007007)3.48131441
66signal transduction involved in DNA integrity checkpoint (GO:0072401)3.47778952
67signal transduction involved in DNA damage checkpoint (GO:0072422)3.47778952
68RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.44572753
69tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.44572753
70DNA strand elongation (GO:0022616)3.42982162
71cellular component biogenesis (GO:0044085)3.42957733
72signal transduction involved in cell cycle checkpoint (GO:0072395)3.41602261
73quinone biosynthetic process (GO:1901663)3.40364492
74GDP-mannose metabolic process (GO:0019673)3.40345458
75UTP biosynthetic process (GO:0006228)3.40340593
76glyoxylate metabolic process (GO:0046487)3.39990187
77antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.38963509
78chaperone-mediated protein transport (GO:0072321)3.38798302
79rRNA modification (GO:0000154)3.38357127
80mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.38248362
81mitochondrial respiratory chain complex I assembly (GO:0032981)3.38248362
82NADH dehydrogenase complex assembly (GO:0010257)3.38248362
83L-serine metabolic process (GO:0006563)3.38086655
84rRNA processing (GO:0006364)3.34983341
85protein complex biogenesis (GO:0070271)3.33087834
86DNA replication checkpoint (GO:0000076)3.30931037
87nucleobase biosynthetic process (GO:0046112)3.30812721
88positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.29780660
89L-methionine salvage (GO:0071267)3.29224407
90L-methionine biosynthetic process (GO:0071265)3.29224407
91amino acid salvage (GO:0043102)3.29224407
92telomere maintenance via recombination (GO:0000722)3.28734606
93deoxyribose phosphate catabolic process (GO:0046386)3.28316045
94purine nucleobase biosynthetic process (GO:0009113)3.27177103
95protein targeting to mitochondrion (GO:0006626)3.27116877
96cytochrome complex assembly (GO:0017004)3.24301119
97metallo-sulfur cluster assembly (GO:0031163)3.24259838
98iron-sulfur cluster assembly (GO:0016226)3.24259838
99CTP biosynthetic process (GO:0006241)3.23635009
100CTP metabolic process (GO:0046036)3.23635009
101DNA replication initiation (GO:0006270)3.21929922
102somatic diversification of immune receptors via somatic mutation (GO:0002566)3.21878922
103somatic hypermutation of immunoglobulin genes (GO:0016446)3.21878922
104rRNA methylation (GO:0031167)3.21403934
105mitochondrial respiratory chain complex assembly (GO:0033108)3.20848553
106rRNA metabolic process (GO:0016072)3.20715032
107positive regulation of mitochondrial fission (GO:0090141)3.20082575
108protein neddylation (GO:0045116)3.19324781
109positive regulation of ligase activity (GO:0051351)3.19131976
110respiratory electron transport chain (GO:0022904)3.18424599
111ribosome biogenesis (GO:0042254)3.17745449
112establishment of protein localization to mitochondrion (GO:0072655)3.17502449
113protein complex disassembly (GO:0043241)3.16995783
114spliceosomal snRNP assembly (GO:0000387)3.16244891
115electron transport chain (GO:0022900)3.14771938
116tRNA processing (GO:0008033)3.11745083
117purine deoxyribonucleotide catabolic process (GO:0009155)3.11584352
118DNA double-strand break processing (GO:0000729)3.11253329
119pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.09541626
120pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.08743669
121macromolecular complex disassembly (GO:0032984)3.08614123
122UTP metabolic process (GO:0046051)3.08093223
1237-methylguanosine mRNA capping (GO:0006370)3.07901731
1247-methylguanosine RNA capping (GO:0009452)3.04752549
125RNA capping (GO:0036260)3.04752549
126exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03616914
1272-deoxyribonucleotide biosynthetic process (GO:0009265)3.02747751
128deoxyribose phosphate biosynthetic process (GO:0046385)3.02747751
129mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.00926623
130pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.00045749
131tRNA metabolic process (GO:0006399)2.99332407
1322-deoxyribonucleotide metabolic process (GO:0009394)2.97954426
133amino acid activation (GO:0043038)2.94321671
134tRNA aminoacylation (GO:0043039)2.94321671
135T cell migration (GO:0072678)2.92416726
136tRNA aminoacylation for protein translation (GO:0006418)2.91881708
137regulation of mitotic spindle checkpoint (GO:1903504)2.91048800
138regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.91048800
139mitochondrial RNA metabolic process (GO:0000959)2.91040244
140base-excision repair (GO:0006284)2.90916325
141protein localization to mitochondrion (GO:0070585)2.90749788
142C-terminal protein lipidation (GO:0006501)2.89234542
143DNA ligation (GO:0006266)2.86903841
144establishment of integrated proviral latency (GO:0075713)2.85958811

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.28996477
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.22943719
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.05381978
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.97723777
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.97148696
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.97047363
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.95612104
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.64666633
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.50442294
10MYC_18358816_ChIP-ChIP_MESCs_Mouse3.05314137
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.99700174
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.99090058
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.88763236
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.64108679
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.63262245
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.62393467
17VDR_23849224_ChIP-Seq_CD4+_Human2.58841327
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.54136040
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.47861314
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.44775368
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.43224241
22DCP1A_22483619_ChIP-Seq_HELA_Human2.42498302
23SRF_21415370_ChIP-Seq_HL-1_Mouse2.41599572
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.22510005
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.21685459
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.21371496
27XRN2_22483619_ChIP-Seq_HELA_Human2.20290160
28THAP11_20581084_ChIP-Seq_MESCs_Mouse2.13911137
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.09930069
30GABP_19822575_ChIP-Seq_HepG2_Human2.08887871
31FOXP3_21729870_ChIP-Seq_TREG_Human2.07643909
32PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.06744667
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.98073339
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.98024399
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.93221873
36TTF2_22483619_ChIP-Seq_HELA_Human1.82514979
37TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.81795127
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81238955
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.78546218
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76043239
41ZNF274_21170338_ChIP-Seq_K562_Hela1.75747526
42CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.71712045
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.70552537
44ELK1_19687146_ChIP-ChIP_HELA_Human1.69298803
45IRF1_19129219_ChIP-ChIP_H3396_Human1.66058273
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.64211057
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57598375
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.56572714
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.55876627
50NOTCH1_21737748_ChIP-Seq_TLL_Human1.49188013
51SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.47252744
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.46919004
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45854888
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41465801
55SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.40373019
56CIITA_25753668_ChIP-Seq_RAJI_Human1.39535881
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38579651
58BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.37279037
59TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.34334951
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31474784
61FOXM1_23109430_ChIP-Seq_U2OS_Human1.29281937
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.25949279
63CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25100909
64TFEB_21752829_ChIP-Seq_HELA_Human1.23504201
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.19958552
66KDM5A_27292631_Chip-Seq_BREAST_Human1.18531674
67SPI1_23547873_ChIP-Seq_NB4_Human1.16012682
68ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09792362
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.09782228
70HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07075996
71SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06752471
72AR_21909140_ChIP-Seq_LNCAP_Human1.06646699
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.05525544
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.04979950
75CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.03166032
76CTCF_18555785_ChIP-Seq_MESCs_Mouse1.03083252
77E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02818569
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00682070
79RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.98921707
80STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98596392
81POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98261204
82FOXP1_21924763_ChIP-Seq_HESCs_Human0.98104411
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.97247408
84MYC_18940864_ChIP-ChIP_HL60_Human0.97098192
85RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.96668443
86CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96512532
87PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96009304
88KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94548145
89FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94391643
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.93316233
91ELF1_20517297_ChIP-Seq_JURKAT_Human0.92973277
92HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.92671575
93PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92063221
94GATA1_22383799_ChIP-Seq_G1ME_Mouse0.87918743
95DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87893650
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.87059359
97YY1_22570637_ChIP-Seq_MALME-3M_Human0.86998894
98DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86196137
99MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.85885687
100SOX2_16153702_ChIP-ChIP_HESCs_Human0.85645656
101MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.84510672
102VDR_21846776_ChIP-Seq_THP-1_Human0.84274053
103BCL6_27268052_Chip-Seq_Bcells_Human0.84043243
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.83640857
105POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.83068999
106STAT4_19710469_ChIP-ChIP_TH1__Mouse0.82248103
107TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80497408
108EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.78841671
109CTCF_26484167_Chip-Seq_Bcells_Mouse0.78260918
110ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.77660943
111SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.77594256
112PU.1_20513432_ChIP-Seq_Bcells_Mouse0.77199007
113TP53_22573176_ChIP-Seq_HFKS_Human0.76954332
114RARB_24833708_ChIP-Seq_LIVER_Mouse0.76459659
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.76208715
116PHF8_20622854_ChIP-Seq_HELA_Human0.75288954

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.91116452
2MP0002653_abnormal_ependyma_morphology4.46481001
3MP0004957_abnormal_blastocyst_morpholog3.50554197
4MP0002102_abnormal_ear_morphology3.47987125
5MP0003806_abnormal_nucleotide_metabolis3.32940157
6MP0004147_increased_porphyrin_level3.19962614
7MP0009379_abnormal_foot_pigmentation3.12713961
8MP0008058_abnormal_DNA_repair3.07263822
9MP0008995_early_reproductive_senescence3.02507531
10MP0010094_abnormal_chromosome_stability2.95610387
11MP0003186_abnormal_redox_activity2.68803415
12MP0003111_abnormal_nucleus_morphology2.67992841
13MP0003077_abnormal_cell_cycle2.67485084
14MP0005645_abnormal_hypothalamus_physiol2.57210561
15MP0006036_abnormal_mitochondrial_physio2.55321828
16MP0008789_abnormal_olfactory_epithelium2.37382617
17MP0002396_abnormal_hematopoietic_system2.33693087
18MP0005075_abnormal_melanosome_morpholog2.21941139
19MP0000490_abnormal_crypts_of2.15183537
20MP0008932_abnormal_embryonic_tissue2.12255142
21MP0003786_premature_aging2.06843721
22MP0008007_abnormal_cellular_replicative2.05592029
23MP0010030_abnormal_orbit_morphology2.04844187
24MP0009333_abnormal_splenocyte_physiolog2.00082468
25MP0003718_maternal_effect1.99126600
26MP0005499_abnormal_olfactory_system1.97083383
27MP0005394_taste/olfaction_phenotype1.97083383
28MP0008057_abnormal_DNA_replication1.90447254
29MP0003878_abnormal_ear_physiology1.89170160
30MP0005377_hearing/vestibular/ear_phenot1.89170160
31MP0002132_abnormal_respiratory_system1.82429317
32MP0003763_abnormal_thymus_physiology1.78123460
33MP0005408_hypopigmentation1.71893796
34MP0005671_abnormal_response_to1.69784207
35MP0003656_abnormal_erythrocyte_physiolo1.67825818
36MP0002938_white_spotting1.63622624
37MP0000749_muscle_degeneration1.59336943
38MP0001835_abnormal_antigen_presentation1.58053108
39MP0006292_abnormal_olfactory_placode1.49863405
40MP0001346_abnormal_lacrimal_gland1.49419629
41MP0009785_altered_susceptibility_to1.46039752
42MP0003122_maternal_imprinting1.44266246
43MP0004043_abnormal_pH_regulation1.41708642
44MP0005058_abnormal_lysosome_morphology1.37305078
45MP0006035_abnormal_mitochondrial_morpho1.36695952
46MP0000685_abnormal_immune_system1.34704834
47MP0001764_abnormal_homeostasis1.34133897
48MP0001529_abnormal_vocalization1.32582827
49MP0000358_abnormal_cell_content/1.30167784
50MP0001730_embryonic_growth_arrest1.29412068
51MP0003646_muscle_fatigue1.29316623
52MP0002160_abnormal_reproductive_system1.27904400
53MP0003724_increased_susceptibility_to1.26044606
54MP0000689_abnormal_spleen_morphology1.25449775
55MP0001545_abnormal_hematopoietic_system1.23987426
56MP0005397_hematopoietic_system_phenotyp1.23987426
57MP0002722_abnormal_immune_system1.23048830
58MP0001853_heart_inflammation1.22411473
59MP0003136_yellow_coat_color1.22294078
60MP0002398_abnormal_bone_marrow1.22080474
61MP0002019_abnormal_tumor_incidence1.20195304
62MP0004145_abnormal_muscle_electrophysio1.19949471
63MP0003252_abnormal_bile_duct1.19930941
64MP0002736_abnormal_nociception_after1.17845578
65MP0002095_abnormal_skin_pigmentation1.17801748
66MP0002148_abnormal_hypersensitivity_rea1.17375342
67MP0008004_abnormal_stomach_pH1.17212751
68MP0004142_abnormal_muscle_tone1.16898914
69MP0000313_abnormal_cell_death1.16856039
70MP0006054_spinal_hemorrhage1.16044486
71MP0003866_abnormal_defecation1.15006229
72MP0000372_irregular_coat_pigmentation1.14328098
73MP0005451_abnormal_body_composition1.13083953
74MP0001984_abnormal_olfaction1.12000965
75MP0005025_abnormal_response_to1.11626508
76MP0002429_abnormal_blood_cell1.09860427
77MP0002420_abnormal_adaptive_immunity1.09714526
78MP0002405_respiratory_system_inflammati1.09529395
79MP0003880_abnormal_central_pattern1.08276727
80MP0001819_abnormal_immune_cell1.07448191
81MP0002277_abnormal_respiratory_mucosa1.07376199
82MP0000703_abnormal_thymus_morphology1.05702564
83MP0000716_abnormal_immune_system1.04611091
84MP0002723_abnormal_immune_serum1.04030422
85MP0004742_abnormal_vestibular_system1.03913978
86MP0004782_abnormal_surfactant_physiolog1.03731498
87MP0005084_abnormal_gallbladder_morpholo1.02932304
88MP0005636_abnormal_mineral_homeostasis1.01955123
89MP0005332_abnormal_amino_acid1.01042361
90MP0001485_abnormal_pinna_reflex1.00969692
91MP0000750_abnormal_muscle_regeneration1.00533607
92MP0005174_abnormal_tail_pigmentation0.99931805
93MP0000350_abnormal_cell_proliferation0.99866784
94MP0001800_abnormal_humoral_immune0.99053333
95MP0004084_abnormal_cardiac_muscle0.98585606
96MP0001119_abnormal_female_reproductive0.98436937
97MP0001873_stomach_inflammation0.96692554
98MP0008873_increased_physiological_sensi0.96450468
99MP0000465_gastrointestinal_hemorrhage0.95723191
100MP0002452_abnormal_antigen_presenting0.95663799
101MP0001293_anophthalmia0.93488417
102MP0000653_abnormal_sex_gland0.92954391
103MP0003315_abnormal_perineum_morphology0.92620021
104MP0000049_abnormal_middle_ear0.92210132
105MP0000858_altered_metastatic_potential0.92209983
106MP0004133_heterotaxia0.91898575
107MP0000516_abnormal_urinary_system0.90709966
108MP0005367_renal/urinary_system_phenotyp0.90709966
109MP0001929_abnormal_gametogenesis0.90511183
110MP0002876_abnormal_thyroid_physiology0.88735408
111MP0005000_abnormal_immune_tolerance0.87691891
112MP0008260_abnormal_autophagy0.87145335
113MP0003137_abnormal_impulse_conducting0.86903327
114MP0006082_CNS_inflammation0.86647475
115MP0005389_reproductive_system_phenotype0.86386279
116MP0005253_abnormal_eye_physiology0.85934263
117MP0003221_abnormal_cardiomyocyte_apopto0.85296992
118MP0005410_abnormal_fertilization0.84582246
119MP0001905_abnormal_dopamine_level0.83901239
120MP0006276_abnormal_autonomic_nervous0.83704756
121MP0002080_prenatal_lethality0.83410363
122MP0000343_altered_response_to0.83265809
123MP0005248_abnormal_Harderian_gland0.82754448
124MP0010155_abnormal_intestine_physiology0.82365538
125MP0001986_abnormal_taste_sensitivity0.80791481
126MP0001270_distended_abdomen0.80514920
127MP0008877_abnormal_DNA_methylation0.80505263
128MP0009697_abnormal_copulation0.80425910
129MP0008875_abnormal_xenobiotic_pharmacok0.79634838
130MP0001697_abnormal_embryo_size0.78305194
131MP0001661_extended_life_span0.78301986
132MP0008469_abnormal_protein_level0.77944858
133MP0005365_abnormal_bile_salt0.77474245
134MP0003698_abnormal_male_reproductive0.77329720
135MP0009278_abnormal_bone_marrow0.76651281
136MP0002210_abnormal_sex_determination0.76085936
137MP0002419_abnormal_innate_immunity0.75910275
138MP0004808_abnormal_hematopoietic_stem0.75445144
139MP0001145_abnormal_male_reproductive0.75170485
140MP0003567_abnormal_fetal_cardiomyocyte0.74735450
141MP0002234_abnormal_pharynx_morphology0.74430586
142MP0005464_abnormal_platelet_physiology0.73890809
143MP0002733_abnormal_thermal_nociception0.73733566
144MP0001919_abnormal_reproductive_system0.72817443
145MP0005551_abnormal_eye_electrophysiolog0.72139263
146MP0004036_abnormal_muscle_relaxation0.71897175
147MP0001845_abnormal_inflammatory_respons0.71135459
148MP0002233_abnormal_nose_morphology0.71090810
149MP0000015_abnormal_ear_pigmentation0.69840081
150MP0005266_abnormal_metabolism0.69536848
151MP0001790_abnormal_immune_system0.67649265

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.31002978
2Abnormal number of erythroid precursors (HP:0012131)5.16838031
3Hepatocellular necrosis (HP:0001404)4.67997466
4Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.67468458
5Decreased activity of mitochondrial respiratory chain (HP:0008972)4.67468458
6Hepatic necrosis (HP:0002605)4.49184941
7Mitochondrial inheritance (HP:0001427)4.31180907
8Acute necrotizing encephalopathy (HP:0006965)4.06707080
9Increased CSF lactate (HP:0002490)4.03584467
103-Methylglutaconic aciduria (HP:0003535)3.90357390
11Abnormal mitochondria in muscle tissue (HP:0008316)3.82044770
12Increased hepatocellular lipid droplets (HP:0006565)3.75492688
13Increased serum lactate (HP:0002151)3.68504650
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.49227312
15Reticulocytopenia (HP:0001896)3.47998587
16Aplastic anemia (HP:0001915)3.47394233
17Exertional dyspnea (HP:0002875)3.46169396
18Lipid accumulation in hepatocytes (HP:0006561)3.44891101
19Cerebral hypomyelination (HP:0006808)3.42890723
20Acute encephalopathy (HP:0006846)3.41998825
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.33561218
22Lactic acidosis (HP:0003128)3.32023285
23Increased intramyocellular lipid droplets (HP:0012240)3.25923696
24Birth length less than 3rd percentile (HP:0003561)3.24754976
25Oral leukoplakia (HP:0002745)3.22633792
26Progressive macrocephaly (HP:0004481)3.14122712
27Macrocytic anemia (HP:0001972)3.13990918
28Type I transferrin isoform profile (HP:0003642)3.08279045
29Renal Fanconi syndrome (HP:0001994)3.07913139
30Microretrognathia (HP:0000308)3.06945892
31Exercise intolerance (HP:0003546)2.96815218
32Increased muscle lipid content (HP:0009058)2.89670599
33Respiratory failure (HP:0002878)2.84606889
34Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.72549115
35Abnormal protein N-linked glycosylation (HP:0012347)2.72549115
36Abnormal protein glycosylation (HP:0012346)2.72549115
37Abnormal glycosylation (HP:0012345)2.72549115
38Thrombocytosis (HP:0001894)2.71115022
39Aplasia/Hypoplasia of the sacrum (HP:0008517)2.67566305
40Hyperglycinemia (HP:0002154)2.64041282
41Respiratory difficulties (HP:0002880)2.63039992
42Abnormality of the labia minora (HP:0012880)2.59791519
43Rough bone trabeculation (HP:0100670)2.59695209
44Pallor (HP:0000980)2.57594915
45Petechiae (HP:0000967)2.56505727
46Failure to thrive in infancy (HP:0001531)2.54508885
47Microvesicular hepatic steatosis (HP:0001414)2.52991942
48Testicular atrophy (HP:0000029)2.52312085
49Emotional lability (HP:0000712)2.47873848
50Increased serum pyruvate (HP:0003542)2.46998709
51Abnormality of glycolysis (HP:0004366)2.46998709
52CNS hypomyelination (HP:0003429)2.43569404
53CNS demyelination (HP:0007305)2.41346530
54Poor head control (HP:0002421)2.35898766
55Premature graying of hair (HP:0002216)2.35051232
56Cerebral palsy (HP:0100021)2.32012461
57IgG deficiency (HP:0004315)2.31585077
58Generalized aminoaciduria (HP:0002909)2.29860674
59Abnormality of the heme biosynthetic pathway (HP:0010472)2.28021907
60Lethargy (HP:0001254)2.26230699
61Abnormality of midbrain morphology (HP:0002418)2.25282002
62Molar tooth sign on MRI (HP:0002419)2.25282002
63Pancytopenia (HP:0001876)2.22929774
64Abnormality of the anterior horn cell (HP:0006802)2.22300318
65Degeneration of anterior horn cells (HP:0002398)2.22300318
66Cerebral edema (HP:0002181)2.21885333
67Decreased electroretinogram (ERG) amplitude (HP:0000654)2.21729623
68Breast hypoplasia (HP:0003187)2.21282019
69Methylmalonic acidemia (HP:0002912)2.19204817
70Multiple enchondromatosis (HP:0005701)2.18591424
71Abnormality of renal resorption (HP:0011038)2.18476665
72Secondary amenorrhea (HP:0000869)2.16623168
73Neoplasm of the adrenal gland (HP:0100631)2.10040011
74Reduced antithrombin III activity (HP:0001976)2.09076389
75Glycosuria (HP:0003076)2.07715291
76Abnormality of urine glucose concentration (HP:0011016)2.07715291
77Rhabdomyolysis (HP:0003201)2.07358350
78Medial flaring of the eyebrow (HP:0010747)2.07153588
79Abnormality of serum amino acid levels (HP:0003112)2.06287688
80Premature ovarian failure (HP:0008209)2.05532390
81Tongue fasciculations (HP:0001308)2.04977837
8211 pairs of ribs (HP:0000878)2.04559315
83Ragged-red muscle fibers (HP:0003200)2.03511698
84Progressive inability to walk (HP:0002505)2.02634624
85Abnormality of the fetal cardiovascular system (HP:0010948)2.02265679
86Abnormal umbilical cord blood vessels (HP:0011403)2.02265679
87Single umbilical artery (HP:0001195)2.02265679
88Progressive muscle weakness (HP:0003323)2.01534755
89Progressive microcephaly (HP:0000253)2.00700226
90Abnormal hemoglobin (HP:0011902)2.00597526
91Stomatitis (HP:0010280)1.99745182
92Abnormal trabecular bone morphology (HP:0100671)1.94770207
93Abnormality of fatty-acid metabolism (HP:0004359)1.94082975
94Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.93943137
95Abnormality of alanine metabolism (HP:0010916)1.93943137
96Hyperalaninemia (HP:0003348)1.93943137
97Abnormal gallbladder physiology (HP:0012438)1.93908740
98Cholecystitis (HP:0001082)1.93908740
99IgM deficiency (HP:0002850)1.92882959
100Nausea (HP:0002018)1.92179171
101Congenital primary aphakia (HP:0007707)1.89614783
102Pulmonary fibrosis (HP:0002206)1.89279163
103Abnormality of dicarboxylic acid metabolism (HP:0010995)1.88966189
104Dicarboxylic aciduria (HP:0003215)1.88966189
105Atrophy/Degeneration involving motor neurons (HP:0007373)1.88413486
106Abnormality of serine family amino acid metabolism (HP:0010894)1.87924980
107Abnormality of glycine metabolism (HP:0010895)1.87924980
108Abnormality of the umbilical cord (HP:0010881)1.87507901
109Severe combined immunodeficiency (HP:0004430)1.87361504
110Leukodystrophy (HP:0002415)1.86800211
111Bone marrow hypocellularity (HP:0005528)1.85889120
112Carpal bone hypoplasia (HP:0001498)1.83795913
113Abnormality of abdominal situs (HP:0011620)1.83205484
114Abdominal situs inversus (HP:0003363)1.83205484
115Retinal dysplasia (HP:0007973)1.82519830
116Gait imbalance (HP:0002141)1.80927963
117B lymphocytopenia (HP:0010976)1.79532014
118Abnormality of B cell number (HP:0010975)1.79532014
119Unsteady gait (HP:0002317)1.79045726
120Colon cancer (HP:0003003)1.78832552
121True hermaphroditism (HP:0010459)1.77738447
122Hyponatremia (HP:0002902)1.77660953
123Sparse eyelashes (HP:0000653)1.77338065
124Postnatal microcephaly (HP:0005484)1.76687341
125Bifid tongue (HP:0010297)1.74219362
126Chromosomal breakage induced by crosslinking agents (HP:0003221)1.71821466
127Hyperglycinuria (HP:0003108)1.70948303
128Nephrogenic diabetes insipidus (HP:0009806)1.70575911
129Inability to walk (HP:0002540)1.68913245
130Abnormality of the axillary hair (HP:0100134)1.68703098
131Abnormality of secondary sexual hair (HP:0009888)1.68703098
132Optic disc pallor (HP:0000543)1.68120500
133Methylmalonic aciduria (HP:0012120)1.68060457
134Absent thumb (HP:0009777)1.67984556
135Neutropenia (HP:0001875)1.67453494
136Palpitations (HP:0001962)1.67371195
137Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.66854573

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.16305209
2TAOK34.14791231
3VRK24.06052411
4NME23.59270704
5SRPK13.36441905
6STK163.34554353
7EIF2AK13.28612835
8WEE13.09003487
9WNK32.82804607
10EIF2AK32.75032393
11TESK22.49110541
12TESK12.37566255
13VRK12.32053696
14TLK12.21276697
15NUAK12.18245672
16PIM22.09283639
17TRIM282.00742804
18BCKDK2.00257948
19TSSK61.94940668
20BCR1.84835987
21NME11.81639640
22MAP3K111.75957344
23PLK41.72900161
24MYLK1.63690452
25ARAF1.63549584
26GRK61.60369345
27MAP4K21.55770741
28MAP4K11.54269547
29CSNK1G31.49924514
30SCYL21.47313274
31BRAF1.43177305
32TBK11.35184690
33IKBKE1.34684283
34LIMK11.34246862
35KDR1.32047945
36ZAK1.28885909
37CSNK1G21.26820662
38BRSK21.25299388
39MAP3K121.25250165
40TEC1.23708685
41CSNK1G11.17275211
42AURKA1.14550204
43CCNB11.10678216
44NEK11.04314900
45CDC71.04285910
46AURKB1.03865324
47NEK21.03549226
48CDK81.02575003
49MAP2K31.01114462
50PLK11.00920816
51TTK0.99663706
52OBSCN0.98842677
53CSNK1A1L0.97852813
54DAPK10.97266763
55ILK0.97140526
56CDK70.96237578
57PBK0.94452414
58STK240.92980492
59RPS6KB20.91672672
60TYK20.89848444
61PASK0.88674899
62MAP3K30.87581538
63CDK190.86104582
64PIK3CG0.85504715
65MAPKAPK30.84236360
66PAK40.80256046
67MAPK150.79187987
68GRK50.78995112
69MST40.78846709
70ACVR1B0.78761122
71EIF2AK20.77588531
72ZAP700.73903691
73BLK0.73644729
74MAP3K80.73242196
75GRK70.73174243
76CSNK2A10.72376797
77PAK10.71861993
78MAP2K70.70486089
79MAP2K60.69960498
80BTK0.69600393
81LRRK20.68364169
82MAPK130.65579321
83CSNK2A20.65521830
84ATR0.64953019
85RPS6KA40.64687178
86PIM10.63744983
87TAOK20.62708922
88BRSK10.62670299
89PLK30.62330310
90TGFBR20.61420973
91EPHA20.58567405
92IKBKB0.58517535
93MUSK0.58322428
94IRAK30.57880096
95CDK30.57752903
96PDK30.57416503
97PDK40.57416503
98PRKCQ0.57113704
99ADRBK20.57039830
100ATM0.56303315
101RIPK40.55783602
102BMPR20.55634827
103DYRK20.54891791
104IRAK40.54618360
105LMTK20.51127815
106INSRR0.50556835
107TGFBR10.49053554
108BMPR1B0.48736129
109PINK10.48143844
110STK40.47314587
111MAP2K20.46820946
112DYRK30.46644434
113PDK20.46257135
114NLK0.45089468
115RPS6KA50.44755603
116TXK0.44592812
117KIT0.43798336
118SYK0.43645059
119AKT30.43365243
120STK100.42565920
121MAP3K140.42484887
122TNIK0.41421767
123FES0.41302096
124LCK0.41154819
125GRK10.40968882
126LYN0.40090406
127CHEK20.37056257
128ABL20.36733442
129PHKG20.34185078
130PHKG10.34185078
131ITK0.33791659
132MAPKAPK50.33150042
133AKT20.31168005
134MAP3K70.29322455
135STK38L0.29047372
136TNK20.28147093

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.69743021
2Proteasome_Homo sapiens_hsa030504.41136973
3RNA polymerase_Homo sapiens_hsa030203.51257672
4DNA replication_Homo sapiens_hsa030303.50759114
5Oxidative phosphorylation_Homo sapiens_hsa001903.08640919
6Mismatch repair_Homo sapiens_hsa034302.90347575
7Parkinsons disease_Homo sapiens_hsa050122.82912540
8Protein export_Homo sapiens_hsa030602.72751163
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.60358933
10Pyrimidine metabolism_Homo sapiens_hsa002402.52244273
11Base excision repair_Homo sapiens_hsa034102.39996449
12Homologous recombination_Homo sapiens_hsa034402.39668209
13Huntingtons disease_Homo sapiens_hsa050162.25858349
14Spliceosome_Homo sapiens_hsa030402.20604087
15Nucleotide excision repair_Homo sapiens_hsa034202.13880463
16RNA transport_Homo sapiens_hsa030131.95711175
17Non-homologous end-joining_Homo sapiens_hsa034501.80972972
18Alzheimers disease_Homo sapiens_hsa050101.78352717
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.76915168
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.72973419
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64318354
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.62697038
23RNA degradation_Homo sapiens_hsa030181.61149599
24Fanconi anemia pathway_Homo sapiens_hsa034601.56863815
25Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.50102993
26Basal transcription factors_Homo sapiens_hsa030221.48850797
27Purine metabolism_Homo sapiens_hsa002301.45188820
28Folate biosynthesis_Homo sapiens_hsa007901.43755950
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.41545006
30Steroid biosynthesis_Homo sapiens_hsa001001.38748365
31One carbon pool by folate_Homo sapiens_hsa006701.33691539
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30866026
33Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.27491429
34Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.25839011
35Cell cycle_Homo sapiens_hsa041101.25790681
36Sulfur relay system_Homo sapiens_hsa041221.24515957
37Glutathione metabolism_Homo sapiens_hsa004801.21531451
38Pentose phosphate pathway_Homo sapiens_hsa000301.17577360
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09286946
40Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.05726330
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.01977981
42Other glycan degradation_Homo sapiens_hsa005110.93856538
43Cardiac muscle contraction_Homo sapiens_hsa042600.92637524
44Epstein-Barr virus infection_Homo sapiens_hsa051690.88302885
45Primary immunodeficiency_Homo sapiens_hsa053400.87642683
46Drug metabolism - other enzymes_Homo sapiens_hsa009830.85462655
472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.84361834
48Carbon metabolism_Homo sapiens_hsa012000.83193621
49p53 signaling pathway_Homo sapiens_hsa041150.83109601
50Fructose and mannose metabolism_Homo sapiens_hsa000510.81756402
51Regulation of autophagy_Homo sapiens_hsa041400.80099596
52Fatty acid elongation_Homo sapiens_hsa000620.79594469
53N-Glycan biosynthesis_Homo sapiens_hsa005100.76664427
54Metabolic pathways_Homo sapiens_hsa011000.75856599
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75691461
56Butanoate metabolism_Homo sapiens_hsa006500.73529911
57Fatty acid metabolism_Homo sapiens_hsa012120.72689458
58Galactose metabolism_Homo sapiens_hsa000520.70506740
59Biosynthesis of amino acids_Homo sapiens_hsa012300.68184924
60Vitamin B6 metabolism_Homo sapiens_hsa007500.65661584
61Type I diabetes mellitus_Homo sapiens_hsa049400.65047349
62Arachidonic acid metabolism_Homo sapiens_hsa005900.64875898
63Pyruvate metabolism_Homo sapiens_hsa006200.62934461
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61671930
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61436836
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58093552
67Antigen processing and presentation_Homo sapiens_hsa046120.57469673
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56522956
69Legionellosis_Homo sapiens_hsa051340.56072329
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53535624
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.52530443
72Autoimmune thyroid disease_Homo sapiens_hsa053200.52312088
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49829747
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49826514
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49114876
76Phenylalanine metabolism_Homo sapiens_hsa003600.49054116
77Selenocompound metabolism_Homo sapiens_hsa004500.48671544
78Allograft rejection_Homo sapiens_hsa053300.47170791
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46332916
80Propanoate metabolism_Homo sapiens_hsa006400.45606651
81Caffeine metabolism_Homo sapiens_hsa002320.44296567
82Herpes simplex infection_Homo sapiens_hsa051680.42059168
83Sulfur metabolism_Homo sapiens_hsa009200.41730041
84Viral myocarditis_Homo sapiens_hsa054160.40587142
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40418479
86beta-Alanine metabolism_Homo sapiens_hsa004100.40408637
87Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38547569
88Hematopoietic cell lineage_Homo sapiens_hsa046400.37902414
89Lysosome_Homo sapiens_hsa041420.36726236
90Sphingolipid metabolism_Homo sapiens_hsa006000.33485468
91Peroxisome_Homo sapiens_hsa041460.33480341
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32940316
93Fatty acid degradation_Homo sapiens_hsa000710.32868523
94Linoleic acid metabolism_Homo sapiens_hsa005910.30370808
95Measles_Homo sapiens_hsa051620.29650598
96Vibrio cholerae infection_Homo sapiens_hsa051100.29553166
97Primary bile acid biosynthesis_Homo sapiens_hsa001200.29527607
98Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27501708
99Arginine and proline metabolism_Homo sapiens_hsa003300.27399454
100Graft-versus-host disease_Homo sapiens_hsa053320.27367645
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26848540
102Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.26021247
103Systemic lupus erythematosus_Homo sapiens_hsa053220.25726305
104mRNA surveillance pathway_Homo sapiens_hsa030150.25425864
105Apoptosis_Homo sapiens_hsa042100.21907608
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21874984
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.21742205
108Renin-angiotensin system_Homo sapiens_hsa046140.21448260
109Vitamin digestion and absorption_Homo sapiens_hsa049770.21104476
110Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.20323222
111Oocyte meiosis_Homo sapiens_hsa041140.19926886
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.19870002
113Cyanoamino acid metabolism_Homo sapiens_hsa004600.19643358
114Viral carcinogenesis_Homo sapiens_hsa052030.19566603
115Collecting duct acid secretion_Homo sapiens_hsa049660.19408593
116Phototransduction_Homo sapiens_hsa047440.19336519
117Arginine biosynthesis_Homo sapiens_hsa002200.18383255
118Maturity onset diabetes of the young_Homo sapiens_hsa049500.18064339
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.17422494
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.16082894
121Shigellosis_Homo sapiens_hsa051310.14972741
122Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14193058
123HTLV-I infection_Homo sapiens_hsa051660.13830441
124Thyroid cancer_Homo sapiens_hsa052160.13254783

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