CDHR4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1GTP biosynthetic process (GO:0006183)9.68500461
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.01755871
3ventricular system development (GO:0021591)8.63535692
4UTP biosynthetic process (GO:0006228)8.63282665
5motile cilium assembly (GO:0044458)8.48737706
6nucleoside diphosphate phosphorylation (GO:0006165)8.25761598
7UTP metabolic process (GO:0046051)7.98261303
8left/right axis specification (GO:0070986)6.96415829
9sperm motility (GO:0030317)6.93169981
10CTP biosynthetic process (GO:0006241)6.51750921
11CTP metabolic process (GO:0046036)6.51750921
12guanosine-containing compound biosynthetic process (GO:1901070)6.33821819
13pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.95707840
14negative regulation of inclusion body assembly (GO:0090084)5.87914970
15fusion of sperm to egg plasma membrane (GO:0007342)5.68676098
16pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.63665245
17acrosome reaction (GO:0007340)5.60059659
18regulation of cilium movement (GO:0003352)5.50326817
19intraciliary transport (GO:0042073)5.48155898
20microtubule bundle formation (GO:0001578)5.33269536
21sperm-egg recognition (GO:0035036)5.22480366
22cilium organization (GO:0044782)5.11998163
23acrosome assembly (GO:0001675)5.11168646
24binding of sperm to zona pellucida (GO:0007339)5.07177815
25spermatid development (GO:0007286)5.04351423
26behavioral response to nicotine (GO:0035095)4.97603176
27vitamin transmembrane transport (GO:0035461)4.84752827
28regulation of inclusion body assembly (GO:0090083)4.76970259
29pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.67845394
30cell-cell recognition (GO:0009988)4.67080651
31cilium assembly (GO:0042384)4.66395676
32multicellular organism reproduction (GO:0032504)4.62143610
33cell wall macromolecule catabolic process (GO:0016998)4.59437137
34cell wall macromolecule metabolic process (GO:0044036)4.59437137
35negative regulation of T cell differentiation in thymus (GO:0033085)4.56723515
36primary alcohol catabolic process (GO:0034310)4.55980113
37plasma membrane fusion (GO:0045026)4.49885693
38microtubule-based movement (GO:0007018)4.43016922
39nucleotide phosphorylation (GO:0046939)4.38656303
40single fertilization (GO:0007338)4.37855495
41L-fucose catabolic process (GO:0042355)4.33335845
42fucose catabolic process (GO:0019317)4.33335845
43L-fucose metabolic process (GO:0042354)4.33335845
44response to xenobiotic stimulus (GO:0009410)4.26731277
45cellular component assembly involved in morphogenesis (GO:0010927)4.24517337
46cilium morphogenesis (GO:0060271)4.23055018
47left/right pattern formation (GO:0060972)4.13404322
48pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.12535186
49brain morphogenesis (GO:0048854)4.05735538
50exogenous drug catabolic process (GO:0042738)4.02076375
51pyrimidine-containing compound transmembrane transport (GO:0072531)3.97033390
52fertilization (GO:0009566)3.96993680
53tolerance induction (GO:0002507)3.93750842
54reproduction (GO:0000003)3.89636244
55nucleoside diphosphate metabolic process (GO:0009132)3.81928360
56ethanol metabolic process (GO:0006067)3.72917041
57synaptonemal complex organization (GO:0070193)3.69787181
58centriole assembly (GO:0098534)3.69705623
59piRNA metabolic process (GO:0034587)3.69697836
60regulation of macrophage chemotaxis (GO:0010758)3.68604377
61one-carbon compound transport (GO:0019755)3.67436812
62diterpenoid biosynthetic process (GO:0016102)3.67158139
63spermatogenesis (GO:0007283)3.66453197
64male gamete generation (GO:0048232)3.63970470
65nonmotile primary cilium assembly (GO:0035058)3.54761285
66cell projection assembly (GO:0030031)3.52687785
67regulation of glucose import in response to insulin stimulus (GO:2001273)3.50337763
68multicellular organismal aging (GO:0010259)3.49555593
69regulation of microtubule-based movement (GO:0060632)3.49487397
70sperm capacitation (GO:0048240)3.46365670
71male meiosis (GO:0007140)3.46059875
72cornea development in camera-type eye (GO:0061303)3.44265135
73secondary metabolite biosynthetic process (GO:0044550)3.43789497
74pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.35454175
75gamete generation (GO:0007276)3.34874496
76microtubule depolymerization (GO:0007019)3.30759166
77drug catabolic process (GO:0042737)3.28224688
78lung epithelium development (GO:0060428)3.25100910
79determination of left/right symmetry (GO:0007368)3.22226375
80gas transport (GO:0015669)3.20077542
81pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.19333965
82microtubule severing (GO:0051013)3.18277535
83retinoic acid metabolic process (GO:0042573)3.13360286
84retinal cone cell development (GO:0046549)3.12629854
85terpenoid biosynthetic process (GO:0016114)3.08294398
86regulation of mononuclear cell migration (GO:0071675)3.05849073
87protein localization to cilium (GO:0061512)3.03520227
88cellular ketone body metabolic process (GO:0046950)3.03518299
89neurotransmitter metabolic process (GO:0042133)3.02837011
90determination of bilateral symmetry (GO:0009855)3.00337107
91otic vesicle formation (GO:0030916)2.97942998
92establishment of planar polarity (GO:0001736)2.94957236
93establishment of tissue polarity (GO:0007164)2.94957236
94purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.94803218
95spinal cord motor neuron differentiation (GO:0021522)2.93942686
96rRNA catabolic process (GO:0016075)2.93514675
97specification of symmetry (GO:0009799)2.92148748
98pyrimidine ribonucleotide metabolic process (GO:0009218)2.90430242
99regulation of pigment cell differentiation (GO:0050932)2.90345217
100protein refolding (GO:0042026)2.87850015
101aldehyde catabolic process (GO:0046185)2.84587855
102purine nucleoside triphosphate biosynthetic process (GO:0009145)2.83707764
103cytoplasmic microtubule organization (GO:0031122)2.82222411
104centriole replication (GO:0007099)2.81375388
105oxygen transport (GO:0015671)2.80985811
106glomerular epithelial cell development (GO:0072310)2.77408866
107microtubule polymerization or depolymerization (GO:0031109)2.77282618
108establishment or maintenance of monopolar cell polarity (GO:0061339)2.77049601
109establishment of monopolar cell polarity (GO:0061162)2.77049601
110spermatid nucleus differentiation (GO:0007289)2.76129673
111hydrogen peroxide biosynthetic process (GO:0050665)2.76065055
112regulation of germinal center formation (GO:0002634)2.75658063
113establishment of apical/basal cell polarity (GO:0035089)2.75521266
114germ cell development (GO:0007281)2.75175910
115male meiosis I (GO:0007141)2.74224738
116lateral ventricle development (GO:0021670)2.73449060
117ketone body metabolic process (GO:1902224)2.73054366
118fucosylation (GO:0036065)2.72157277
119eye photoreceptor cell differentiation (GO:0001754)2.71939517
120photoreceptor cell differentiation (GO:0046530)2.71939517
121photoreceptor cell maintenance (GO:0045494)2.71461895
122negative regulation of B cell mediated immunity (GO:0002713)2.71397637
123negative regulation of immunoglobulin mediated immune response (GO:0002890)2.71397637
124blood vessel maturation (GO:0001955)2.70333408
125positive regulation of tolerance induction (GO:0002645)2.69036051
126negative regulation of telomere maintenance (GO:0032205)2.68020622
127response to pheromone (GO:0019236)2.67785002
128multicellular organismal reproductive process (GO:0048609)2.67676053
129ethanol oxidation (GO:0006069)2.65817521
130melanin biosynthetic process (GO:0042438)2.65356450
131synaptonemal complex assembly (GO:0007130)2.63798099
132smoothened signaling pathway (GO:0007224)2.61761168
133cell recognition (GO:0008037)2.59760354
134lateral sprouting from an epithelium (GO:0060601)2.58875334
135neuronal action potential (GO:0019228)2.58530029
136response to histamine (GO:0034776)2.58034095
137regulation of interleukin-5 production (GO:0032674)2.57419120
138axon ensheathment in central nervous system (GO:0032291)2.56832919
139central nervous system myelination (GO:0022010)2.56832919
140neurotransmitter biosynthetic process (GO:0042136)2.56485864
141negative regulation of humoral immune response (GO:0002921)2.56463522
142cellular process involved in reproduction in multicellular organism (GO:0022412)2.55772824
143surfactant homeostasis (GO:0043129)2.55757013
144ubiquinone biosynthetic process (GO:0006744)2.54894924
145ribonucleoside triphosphate biosynthetic process (GO:0009201)2.50335156
146DNA deamination (GO:0045006)2.49684478
147reactive oxygen species biosynthetic process (GO:1903409)2.49340292
148protein polyglutamylation (GO:0018095)2.48322992
149neural tube formation (GO:0001841)2.47995924
150L-ascorbic acid metabolic process (GO:0019852)2.47935192
151intra-S DNA damage checkpoint (GO:0031573)2.46330782
152behavioral response to ethanol (GO:0048149)2.45823833
153organic cation transport (GO:0015695)2.45554331
154regulation of collateral sprouting (GO:0048670)2.45071291
155benzene-containing compound metabolic process (GO:0042537)2.43885677
156retinal rod cell development (GO:0046548)2.43098242
157ubiquinone metabolic process (GO:0006743)2.40403246
158phenol-containing compound catabolic process (GO:0019336)2.38695197
159indole-containing compound catabolic process (GO:0042436)2.30753487
160indolalkylamine catabolic process (GO:0046218)2.30753487
161tryptophan catabolic process (GO:0006569)2.30753487
162detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.29806932
163indolalkylamine metabolic process (GO:0006586)2.29519110
164kynurenine metabolic process (GO:0070189)2.26907479
165cilium movement (GO:0003341)14.7392057
166cilium or flagellum-dependent cell motility (GO:0001539)13.8113448
167axonemal dynein complex assembly (GO:0070286)13.4052265
168epithelial cilium movement (GO:0003351)11.9768534
169axoneme assembly (GO:0035082)11.6089715

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.97016773
2VDR_22108803_ChIP-Seq_LS180_Human3.67342305
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.61875583
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.06065754
5EZH2_22144423_ChIP-Seq_EOC_Human2.68422472
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.66517480
7CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.61125652
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.49762007
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.16025665
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.01706074
11CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92991720
12GBX2_23144817_ChIP-Seq_PC3_Human1.92316477
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.89702532
14EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.87448126
15FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.82591705
16FUS_26573619_Chip-Seq_HEK293_Human1.61471570
17BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61354193
18SUZ12_27294783_Chip-Seq_ESCs_Mouse1.59681150
19TAF15_26573619_Chip-Seq_HEK293_Human1.59216926
20DROSHA_22980978_ChIP-Seq_HELA_Human1.53764772
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53617875
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53053310
23POU3F2_20337985_ChIP-ChIP_501MEL_Human1.52115098
24CBX2_27304074_Chip-Seq_ESCs_Mouse1.51933349
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.51427553
26FOXA1_25329375_ChIP-Seq_VCAP_Human1.50178577
27FOXA1_27270436_Chip-Seq_PROSTATE_Human1.50178577
28EWS_26573619_Chip-Seq_HEK293_Human1.48810882
29SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.46809323
30EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.46350416
31SMAD4_21799915_ChIP-Seq_A2780_Human1.43664471
32TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43262138
33BCAT_22108803_ChIP-Seq_LS180_Human1.36934489
34TDRD3_21172665_ChIP-Seq_MCF-7_Human1.35826365
35NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35027839
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34537094
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34286492
38AR_20517297_ChIP-Seq_VCAP_Human1.33134256
39STAT3_23295773_ChIP-Seq_U87_Human1.33028270
40SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32222898
41GATA3_21878914_ChIP-Seq_MCF-7_Human1.32081590
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.31573141
43ARNT_22903824_ChIP-Seq_MCF-7_Human1.31483025
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30008634
45SMAD4_21741376_ChIP-Seq_EPCs_Human1.29750214
46SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.29227639
47IGF1R_20145208_ChIP-Seq_DFB_Human1.28979475
48MTF2_20144788_ChIP-Seq_MESCs_Mouse1.27829280
49CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.27448964
50TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.26950000
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.26565979
52MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.25897043
53LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24684716
54PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.23099558
55NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.22173733
56SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.21720015
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21606457
58ER_23166858_ChIP-Seq_MCF-7_Human1.20853273
59HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.20772644
60ETV1_20927104_ChIP-Seq_GIST48_Human1.20724538
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.20576509
62FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20296554
63TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.19788472
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.19528999
65NCOR_22424771_ChIP-Seq_293T_Human1.18271264
66TP53_22573176_ChIP-Seq_HFKS_Human1.17977655
67SOX2_19829295_ChIP-Seq_ESCs_Human1.17732683
68NANOG_19829295_ChIP-Seq_ESCs_Human1.17732683
69MYC_19829295_ChIP-Seq_ESCs_Human1.16676592
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.16401944
71EP300_21415370_ChIP-Seq_HL-1_Mouse1.16206528
72CBP_20019798_ChIP-Seq_JUKART_Human1.15995442
73IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15995442
74PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.15197227
75HOXB7_26014856_ChIP-Seq_BT474_Human1.14768175
76P300_19829295_ChIP-Seq_ESCs_Human1.14507200
77SMAD3_21741376_ChIP-Seq_ESCs_Human1.13664083
78PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13266317
79SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.11721740
80TAF2_19829295_ChIP-Seq_ESCs_Human1.11546519
81AHR_22903824_ChIP-Seq_MCF-7_Human1.11332478
82RUNX2_22187159_ChIP-Seq_PCA_Human1.11195607
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11146914
84* ERA_21632823_ChIP-Seq_H3396_Human1.09710300
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09449673
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09033676
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08932535
88TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.08829349
89ZNF274_21170338_ChIP-Seq_K562_Hela1.08797312
90RING1B_27294783_Chip-Seq_ESCs_Mouse1.08621891
91TP53_18474530_ChIP-ChIP_U2OS_Human1.08567107
92PHF8_20622853_ChIP-Seq_HELA_Human1.08200771
93SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08109487
94WDR5_24793694_ChIP-Seq_LNCAP_Human1.07410180
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06903965
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06781394
97PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06780646
98EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.06757415
99ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06153192
100BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.06046073
101PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.05934203
102CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05580496
103OCT4_20526341_ChIP-Seq_ESCs_Human1.05534821
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05016576
105FLI1_21867929_ChIP-Seq_TH2_Mouse1.04582617
106NANOG_20526341_ChIP-Seq_ESCs_Human1.04366292
107PRDM14_20953172_ChIP-Seq_ESCs_Human1.03953528
108RBPJ_21746931_ChIP-Seq_IB4_Human1.03504290
109RNF2_27304074_Chip-Seq_NSC_Mouse1.03464846
110POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02919494
111TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02919494
112RNF2_27304074_Chip-Seq_ESCs_Mouse1.02823371
113NFE2_27457419_Chip-Seq_LIVER_Mouse1.02157643
114IRF1_19129219_ChIP-ChIP_H3396_Human1.01943289
115FLI1_27457419_Chip-Seq_LIVER_Mouse1.01623437
116AR_25329375_ChIP-Seq_VCAP_Human1.00797947
117SMRT_27268052_Chip-Seq_Bcells_Human1.00793580
118TP53_16413492_ChIP-PET_HCT116_Human1.00405703
119CJUN_26792858_Chip-Seq_BT549_Human1.00279189
120ZNF217_24962896_ChIP-Seq_MCF-7_Human0.99826174
121SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.99362709
122SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.99337280
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.98924711
124VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98845861
125GF1_26923725_Chip-Seq_HPCs_Mouse0.98670893
126PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.98319675
127EED_16625203_ChIP-ChIP_MESCs_Mouse0.97633407
128TAL1_26923725_Chip-Seq_HPCs_Mouse0.97490079
129EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.95329455
130EZH2_27304074_Chip-Seq_ESCs_Mouse0.94759027
131SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.94330529
132STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93659439
133AR_21572438_ChIP-Seq_LNCaP_Human0.93611750
134TOP2B_26459242_ChIP-Seq_MCF-7_Human0.93299702
135ELK4_26923725_Chip-Seq_MESODERM_Mouse0.93084177
136ZFP57_27257070_Chip-Seq_ESCs_Mouse0.92930904
137GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.92373104
138CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.92093853
139ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.91817941
140FOXM1_26456572_ChIP-Seq_MCF-7_Human0.91699694
141JARID2_20075857_ChIP-Seq_MESCs_Mouse0.91671403
142CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91630491
143EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91231103
144SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90770534
145TBL1_22424771_ChIP-Seq_293T_Human0.90145256
146TCF4_22108803_ChIP-Seq_LS180_Human0.89979781
147PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.89130019
148SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88546101
149CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.88226461
150TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.87626180
151NANOG_18555785_Chip-Seq_ESCs_Mouse0.86992578
152ERG_20517297_ChIP-Seq_VCAP_Human0.85679354
153STAT1_17558387_ChIP-Seq_HELA_Human0.85457726
154* SOX2_22085726_ChIP-Seq_NPCs_Mouse0.85423932
155REST_21632747_ChIP-Seq_MESCs_Mouse0.85419426
156TCF4_23295773_ChIP-Seq_U87_Human0.85230571

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization7.75020349
2MP0003136_yellow_coat_color6.69732040
3MP0005623_abnormal_meninges_morphology4.74663387
4MP0002653_abnormal_ependyma_morphology3.87991521
5MP0004043_abnormal_pH_regulation3.27013419
6MP0008004_abnormal_stomach_pH3.25115528
7MP0002277_abnormal_respiratory_mucosa3.09552206
8MP0003698_abnormal_male_reproductive2.99982745
9MP0003724_increased_susceptibility_to2.75083924
10MP0001929_abnormal_gametogenesis2.60808722
11MP0002282_abnormal_trachea_morphology2.42749249
12MP0004133_heterotaxia2.35935954
13MP0001958_emphysema2.34228464
14MP0001851_eye_inflammation2.26762893
15MP0003195_calcinosis2.24233911
16MP0003950_abnormal_plasma_membrane2.14202386
17MP0009379_abnormal_foot_pigmentation2.13488670
18MP0004381_abnormal_hair_follicle2.09792153
19MP0002638_abnormal_pupillary_reflex2.02634534
20MP0008995_early_reproductive_senescence1.98124029
21MP0008789_abnormal_olfactory_epithelium1.97286750
22MP0001485_abnormal_pinna_reflex1.90043298
23MP0000383_abnormal_hair_follicle1.84924839
24MP0002876_abnormal_thyroid_physiology1.67901540
25MP0005646_abnormal_pituitary_gland1.63410301
26MP0005388_respiratory_system_phenotype1.61271287
27MP0002133_abnormal_respiratory_system1.61271287
28MP0003303_peritoneal_inflammation1.58975728
29MP0009046_muscle_twitch1.58746320
30MP0000566_synostosis1.57681620
31MP0002161_abnormal_fertility/fecundity1.55898497
32MP0002210_abnormal_sex_determination1.51693648
33MP0001879_abnormal_lymphatic_vessel1.49757137
34MP0002735_abnormal_chemical_nociception1.46392269
35MP0008872_abnormal_physiological_respon1.45909618
36MP0009780_abnormal_chondrocyte_physiolo1.45355282
37MP0003878_abnormal_ear_physiology1.44453613
38MP0005377_hearing/vestibular/ear_phenot1.44453613
39MP0004019_abnormal_vitamin_homeostasis1.39492632
40MP0001501_abnormal_sleep_pattern1.37986699
41MP0003279_aneurysm1.37231552
42MP0005075_abnormal_melanosome_morpholog1.36983268
43MP0005389_reproductive_system_phenotype1.36772211
44MP0004272_abnormal_basement_membrane1.35814770
45MP0002160_abnormal_reproductive_system1.33249519
46MP0001270_distended_abdomen1.32870687
47MP0005499_abnormal_olfactory_system1.30187599
48MP0005394_taste/olfaction_phenotype1.30187599
49MP0002234_abnormal_pharynx_morphology1.29600658
50MP0000428_abnormal_craniofacial_morphol1.29409526
51MP0002272_abnormal_nervous_system1.28861961
52MP0006054_spinal_hemorrhage1.28667995
53MP0000631_abnormal_neuroendocrine_gland1.27115702
54MP0003690_abnormal_glial_cell1.25870082
55MP0004742_abnormal_vestibular_system1.23484727
56MP0003937_abnormal_limbs/digits/tail_de1.21687481
57MP0002734_abnormal_mechanical_nocicepti1.21400230
58MP0004858_abnormal_nervous_system1.21216312
59MP0003828_pulmonary_edema1.19279261
60MP0001145_abnormal_male_reproductive1.18583481
61MP0001986_abnormal_taste_sensitivity1.17133665
62MP0002254_reproductive_system_inflammat1.16369307
63MP0002572_abnormal_emotion/affect_behav1.14570837
64MP0005167_abnormal_blood-brain_barrier1.13765121
65MP0004782_abnormal_surfactant_physiolog1.13758275
66MP0001440_abnormal_grooming_behavior1.13552339
67MP0003283_abnormal_digestive_organ1.10334429
68MP0001970_abnormal_pain_threshold1.10152031
69MP0001486_abnormal_startle_reflex1.10012780
70MP0005645_abnormal_hypothalamus_physiol1.09939706
71MP0000569_abnormal_digit_pigmentation1.09897984
72MP0002938_white_spotting1.09790497
73MP0000026_abnormal_inner_ear1.09523314
74MP0005195_abnormal_posterior_eye1.08268117
75MP0002405_respiratory_system_inflammati1.08120624
76MP0006138_congestive_heart_failure1.07519344
77MP0003634_abnormal_glial_cell1.07233194
78MP0008961_abnormal_basal_metabolism1.07189015
79MP0003646_muscle_fatigue1.05685970
80MP0004885_abnormal_endolymph1.05492219
81MP0000653_abnormal_sex_gland1.04743483
82MP0010368_abnormal_lymphatic_system1.04632809
83MP0002102_abnormal_ear_morphology1.04124308
84MP0003122_maternal_imprinting1.03011939
85MP0003890_abnormal_embryonic-extraembry1.02410909
86MP0006072_abnormal_retinal_apoptosis1.02254779
87MP0001188_hyperpigmentation1.00329578
88MP0008875_abnormal_xenobiotic_pharmacok0.98905912
89MP0005171_absent_coat_pigmentation0.98558109
90MP0004147_increased_porphyrin_level0.97756330
91MP0010678_abnormal_skin_adnexa0.97739479
92MP0001905_abnormal_dopamine_level0.95849101
93MP0000049_abnormal_middle_ear0.95721232
94MP0001324_abnormal_eye_pigmentation0.95269569
95MP0004264_abnormal_extraembryonic_tissu0.92657976
96MP0002249_abnormal_larynx_morphology0.92592309
97MP0001529_abnormal_vocalization0.91171581
98MP0001502_abnormal_circadian_rhythm0.90622858
99MP0003075_altered_response_to0.90067177
100MP0002837_dystrophic_cardiac_calcinosis0.89171399
101MP0006276_abnormal_autonomic_nervous0.88431870
102MP0001293_anophthalmia0.88139589
103MP0002067_abnormal_sensory_capabilities0.87694987
104MP0008877_abnormal_DNA_methylation0.87148714
105MP0002095_abnormal_skin_pigmentation0.86081849
106MP0005085_abnormal_gallbladder_physiolo0.86059521
107MP0002733_abnormal_thermal_nociception0.85391739
108MP0002736_abnormal_nociception_after0.85246797
109MP0005174_abnormal_tail_pigmentation0.85041979
110MP0005636_abnormal_mineral_homeostasis0.84853695
111MP0000427_abnormal_hair_cycle0.84590837
112MP0003942_abnormal_urinary_system0.84274381
113MP0000470_abnormal_stomach_morphology0.83722415
114MP0002229_neurodegeneration0.82283413
115MP0001963_abnormal_hearing_physiology0.81971327
116MP0003943_abnormal_hepatobiliary_system0.81746702
117MP0002132_abnormal_respiratory_system0.81244284
118MP0002909_abnormal_adrenal_gland0.81074358
119MP0001765_abnormal_ion_homeostasis0.79922218
120MP0002752_abnormal_somatic_nervous0.79820382
121MP0002168_other_aberrant_phenotype0.79703749
122MP0001919_abnormal_reproductive_system0.78820645
123MP0003115_abnormal_respiratory_system0.78557225
124MP0005083_abnormal_biliary_tract0.78261417
125MP0001984_abnormal_olfaction0.78083731
126MP0002063_abnormal_learning/memory/cond0.78002290
127MP0003938_abnormal_ear_development0.77086716
128MP0009384_cardiac_valve_regurgitation0.77028748
129MP0005365_abnormal_bile_salt0.76212510
130MP0001177_atelectasis0.76152737
131MP0004145_abnormal_muscle_electrophysio0.75456055
132MP0001664_abnormal_digestion0.75089416
133MP0003635_abnormal_synaptic_transmissio0.74639540
134MP0003011_delayed_dark_adaptation0.74178694
135MP0010030_abnormal_orbit_morphology0.73584581
136MP0002928_abnormal_bile_duct0.73269015
137MP0009250_abnormal_appendicular_skeleto0.72261954
138MP0005647_abnormal_sex_gland0.71762231
139MP0005670_abnormal_white_adipose0.71581004
140MP0000534_abnormal_ureter_morphology0.71099859
141MP0001663_abnormal_digestive_system0.70918252
142MP0005164_abnormal_response_to0.69479407
143MP0000372_irregular_coat_pigmentation0.66965707
144MP0002557_abnormal_social/conspecific_i0.66378616
145MP0005595_abnormal_vascular_smooth0.66358906
146MP0003880_abnormal_central_pattern0.66244497
147MP0002064_seizures0.64039069
148MP0005551_abnormal_eye_electrophysiolog0.63882876
149MP0003329_amyloid_beta_deposits0.63763460
150MP0002295_abnormal_pulmonary_circulatio0.62470397
151MP0001175_abnormal_lung_morphology0.61989198
152MP0004142_abnormal_muscle_tone0.61257258
153MP0001968_abnormal_touch/_nociception0.61038370
154MP0009745_abnormal_behavioral_response0.60827808
155MP0005423_abnormal_somatic_nervous0.58960567
156MP0001943_abnormal_respiration0.58797804
157MP0005381_digestive/alimentary_phenotyp0.58672335
158MP0001873_stomach_inflammation0.57282354
159MP0003045_fibrosis0.56148000
160MP0002116_abnormal_craniofacial_bone0.56142565
161MP0005253_abnormal_eye_physiology0.54579431

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.84028803
2Abnormal respiratory motile cilium morphology (HP:0005938)9.49035643
3Abnormal respiratory epithelium morphology (HP:0012253)9.49035643
4Absent/shortened dynein arms (HP:0200106)9.40366659
5Dynein arm defect of respiratory motile cilia (HP:0012255)9.40366659
6Chronic bronchitis (HP:0004469)7.70104026
7Nasal polyposis (HP:0100582)6.03700167
8Bronchiectasis (HP:0002110)5.82863461
9Abnormality of the nasal mucosa (HP:0000433)5.48244946
10Bronchitis (HP:0012387)4.47782798
11Chronic sinusitis (HP:0011109)3.86625513
12Recurrent sinusitis (HP:0011108)3.74921525
13Infertility (HP:0000789)3.67286517
14Pancreatic fibrosis (HP:0100732)3.54192210
15True hermaphroditism (HP:0010459)3.41677191
16Nephronophthisis (HP:0000090)3.24920666
17Recurrent otitis media (HP:0000403)2.84410828
18Supernumerary spleens (HP:0009799)2.79022262
19Tubulointerstitial nephritis (HP:0001970)2.70032306
20Median cleft lip (HP:0000161)2.54691952
21Chronic otitis media (HP:0000389)2.49732763
22Furrowed tongue (HP:0000221)2.47960690
23Decreased circulating renin level (HP:0003351)2.45947042
24Postaxial foot polydactyly (HP:0001830)2.45941824
25Abnormality of the renal medulla (HP:0100957)2.45634673
26Male infertility (HP:0003251)2.44446822
27Abnormality of midbrain morphology (HP:0002418)2.42371852
28Molar tooth sign on MRI (HP:0002419)2.42371852
29Abnormality of dentin (HP:0010299)2.39295464
30Occipital encephalocele (HP:0002085)2.35617972
31Medial flaring of the eyebrow (HP:0010747)2.34258100
32Recurrent bronchitis (HP:0002837)2.32901979
33Neoplasm of head and neck (HP:0012288)2.29522636
34Esophageal neoplasm (HP:0100751)2.29522636
35Fibular hypoplasia (HP:0003038)2.27269341
36Abnormality of the renal cortex (HP:0011035)2.21324083
37Congenital stationary night blindness (HP:0007642)2.19471394
38Cystic liver disease (HP:0006706)2.18280271
39Pancreatic cysts (HP:0001737)2.18199779
40Aplasia/Hypoplasia of the tongue (HP:0010295)2.17991713
41Congenital hepatic fibrosis (HP:0002612)2.16377204
42Gait imbalance (HP:0002141)2.11178290
43Congenital primary aphakia (HP:0007707)2.08146053
44Abnormal umbilical cord blood vessels (HP:0011403)2.07369251
45Single umbilical artery (HP:0001195)2.07369251
46Abnormality of the fetal cardiovascular system (HP:0010948)2.07369251
47Tubular atrophy (HP:0000092)2.06304069
48Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.3286139
49Abnormal respiratory motile cilium physiology (HP:0012261)11.7904864
50Abnormal ciliary motility (HP:0012262)11.2998396
51Tubulointerstitial abnormality (HP:0001969)1.99914102
52Bile duct proliferation (HP:0001408)1.98244397
53Abnormal biliary tract physiology (HP:0012439)1.98244397
54Type II lissencephaly (HP:0007260)1.89850177
55Genital tract atresia (HP:0001827)1.87752451
56Absent rod-and cone-mediated responses on ERG (HP:0007688)1.86929622
57Abnormal rod and cone electroretinograms (HP:0008323)1.84738484
58Stage 5 chronic kidney disease (HP:0003774)1.84417601
59Abnormality of the dental root (HP:0006486)1.77645877
60Taurodontia (HP:0000679)1.77645877
61Abnormality of permanent molar morphology (HP:0011071)1.77645877
62Nephrogenic diabetes insipidus (HP:0009806)1.76872683
63Broad distal phalanx of finger (HP:0009836)1.74829602
64Abnormality of renin-angiotensin system (HP:0000847)1.74537374
65Renal salt wasting (HP:0000127)1.72839099
66Tubulointerstitial fibrosis (HP:0005576)1.70136409
67Bronchomalacia (HP:0002780)1.67184793
68Large for gestational age (HP:0001520)1.65805108
69Neonatal short-limb short stature (HP:0008921)1.63100519
70Congenital, generalized hypertrichosis (HP:0004540)1.62963225
71Abnormality of molar (HP:0011077)1.62639084
72Abnormality of molar morphology (HP:0011070)1.62639084
73Neurofibrillary tangles (HP:0002185)1.62467937
74Polyuria (HP:0000103)1.61175717
75Hyperaldosteronism (HP:0000859)1.60544934
76Abnormality of the dental pulp (HP:0006479)1.58613933
77Male pseudohermaphroditism (HP:0000037)1.57399412
78Postaxial hand polydactyly (HP:0001162)1.57330659
79Anencephaly (HP:0002323)1.56924374
80Vaginal atresia (HP:0000148)1.55612157
81Abolished electroretinogram (ERG) (HP:0000550)1.48689476
82Asplenia (HP:0001746)1.47933034
83Hypokalemic alkalosis (HP:0001949)1.47646968
84Preaxial hand polydactyly (HP:0001177)1.47450435
85Facial cleft (HP:0002006)1.45824830
86Attenuation of retinal blood vessels (HP:0007843)1.44101028
87Chronic hepatic failure (HP:0100626)1.43351666
88Atelectasis (HP:0100750)1.42762289
89Hyperactive renin-angiotensin system (HP:0000841)1.42609203
90Microglossia (HP:0000171)1.41033843
91Birth length less than 3rd percentile (HP:0003561)1.40419514
92Retinitis pigmentosa (HP:0000510)1.39328657
93Metaphyseal dysplasia (HP:0100255)1.38448207
94Aplasia/Hypoplasia of the lens (HP:0008063)1.37921864
95Abnormal sex determination (HP:0012244)1.37463434
96Sex reversal (HP:0012245)1.37463434
97Abnormality of chloride homeostasis (HP:0011422)1.37012735
98Aplasia/Hypoplasia of the spleen (HP:0010451)1.33507990
99Poor coordination (HP:0002370)1.33042460
100Absent speech (HP:0001344)1.33016509
101Oculomotor apraxia (HP:0000657)1.32650577
102Abnormality of renal excretion (HP:0011036)1.32078474
103Aplasia/Hypoplasia of the fibula (HP:0006492)1.31523242
104Abnormal drinking behavior (HP:0030082)1.31293701
105Polydipsia (HP:0001959)1.31293701
106Abnormality of the umbilical cord (HP:0010881)1.31178101
107Short nail (HP:0001799)1.30710784
108Inability to walk (HP:0002540)1.29378592
109Constricted visual fields (HP:0001133)1.28844351
110Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.28480500
111Abnormality of alanine metabolism (HP:0010916)1.28480500
112Hyperalaninemia (HP:0003348)1.28480500
113Hyperventilation (HP:0002883)1.28437858
114Anophthalmia (HP:0000528)1.28282688
115Abnormality of macular pigmentation (HP:0008002)1.28028269
116Abnormal urine output (HP:0012590)1.27794708
117Sclerocornea (HP:0000647)1.27488188
118Aganglionic megacolon (HP:0002251)1.27031414
119Hypotelorism (HP:0000601)1.26769758
120Back pain (HP:0003418)1.26287638
121Disproportionate short-trunk short stature (HP:0003521)1.25293044
122Cerebral inclusion bodies (HP:0100314)1.25268518
123Bell-shaped thorax (HP:0001591)1.25080521
124Bony spicule pigmentary retinopathy (HP:0007737)1.23699444
125Optic nerve coloboma (HP:0000588)1.23099291
126Multicystic kidney dysplasia (HP:0000003)1.22593636
127Decreased central vision (HP:0007663)1.22235977
128Nephropathy (HP:0000112)1.22232846
129Retinal dysplasia (HP:0007973)1.21619330
130Narrow forehead (HP:0000341)1.21373983
131Hyperkalemia (HP:0002153)1.20956964
132Short ribs (HP:0000773)1.19514299
13311 pairs of ribs (HP:0000878)1.16023376
134Narrow chest (HP:0000774)1.15570316
135Concave nail (HP:0001598)1.15560986
136Polycythemia (HP:0001901)1.14594078
137Abnormality of abdominal situs (HP:0011620)1.13073366

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK157.26542883
2PNCK6.34554947
3PDK43.84208949
4PDK33.84208949
5TLK13.76694640
6MST42.87139731
7TESK12.64966096
8FRK2.62847999
9PTK2B2.33124016
10PDK22.30384806
11INSRR2.29502752
12MAP2K22.27470576
13BMPR1B2.26738801
14ICK2.14480935
15WNK31.88821335
16STK391.88412361
17TIE11.88185163
18ACVR1B1.78490527
19PRKD31.77548274
20ZAK1.77007762
21MAPKAPK31.75693603
22GRK11.69925282
23NTRK21.69062123
24PINK11.65328772
25EPHA21.63049212
26MAPK131.58303285
27OXSR11.57405285
28MAP4K21.47745229
29WNK41.46702327
30WEE11.40358711
31STK101.37824980
32DAPK21.36728998
33NLK1.36709619
34MAPKAPK51.36287963
35LRRK21.30423861
36CASK1.27516357
37MAP3K41.27020338
38PIK3CA1.23875922
39TSSK61.19182750
40PAK21.16658577
41BCR1.10777374
42CAMK1G1.05437060
43DYRK21.03323702
44CDK191.01549825
45DYRK30.96595129
46EPHB10.94318452
47PRKCI0.92614093
48GSK3A0.91608246
49ADRBK20.91063384
50EEF2K0.90973245
51ITK0.90203532
52TAOK30.87847704
53TGFBR20.87039275
54BRSK20.86920601
55IRAK10.84651017
56MAP2K70.84188537
57ROCK20.80446868
58TEC0.79324807
59PRKCQ0.79289660
60MARK10.77698811
61NUAK10.76085332
62PTK60.75318981
63STK30.73754945
64CSK0.71898529
65MYLK0.70724093
66PAK40.68969068
67VRK10.66257770
68SCYL20.65990000
69TXK0.65779735
70MATK0.64996349
71CAMKK20.63405585
72CAMKK10.63380552
73AURKA0.61110057
74FES0.60529133
75MUSK0.59792045
76PHKG20.59228208
77PHKG10.59228208
78LMTK20.59112501
79PASK0.58960553
80FER0.58643074
81KIT0.58093916
82STK110.57488120
83IRAK40.57475835
84MKNK20.57279260
85ROCK10.55813296
86CAMK2A0.54798847
87RPS6KA20.54633827
88RPS6KA50.54076922
89PRKCE0.53321991
90NTRK30.51126270
91CDK30.50809127
92PRKACA0.50249242
93DMPK0.49081480
94WNK10.48805130
95ERBB20.48253665
96BTK0.48033803
97MST1R0.45987895
98ERBB30.45707880
99PTK20.45586350
100DDR20.45061149
101MAPK120.44119084
102LIMK10.44036056
103FGFR20.43934988
104PRKAA20.42938478
105DYRK1A0.42492736
106CSNK1G20.42348042
107SGK2230.42150918
108SGK4940.42150918
109PDGFRA0.41277163
110PKN10.40440675
111SRC0.40272124
112TNIK0.39961785
113LATS10.39736246
114PRKCA0.38806092
115NEK20.38260576
116TTK0.37813434
117NME10.37647528
118STK38L0.37572044
119EGFR0.37432341
120ADRBK10.36799249
121TYRO30.35464564
122SIK20.34657630
123CSNK1G10.34140319
124MAPKAPK20.33942712
125MARK20.33669807
126PRKCG0.33506090
127MAP2K30.33498248
128STK240.32900216
129PRKCD0.32848930
130MAP2K10.32784153
131GRK70.32732689
132MAP2K60.31328161
133TRPM70.31324439
134ABL10.30278971
135EPHA40.28955898
136PRKG10.28843248
137PDK10.28242925
138DYRK1B0.27336406
139CHUK0.26446423
140FYN0.25508313
141TRIM280.25205546
142FGR0.24909508
143MAP3K70.23904126
144PRKCZ0.23597098
145PAK10.23177779
146GRK60.23078565
147TRIB30.23060978
148PLK10.22779498
149CAMK10.22747394
150PAK30.22683964
151CAMK1D0.22589129
152TGFBR10.22140046
153MINK10.21856405
154MKNK10.21797360
155NTRK10.21785649
156MAP2K40.21583415
157NEK60.21006744
158MAP3K20.20984578
159RPS6KC10.20521348

Predicted pathways (KEGG)

RankGene SetZ-score
1Huntingtons disease_Homo sapiens_hsa050162.85027167
2Vitamin B6 metabolism_Homo sapiens_hsa007502.63134179
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.60777355
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.35811345
5Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.24989970
6Phototransduction_Homo sapiens_hsa047442.21629048
7Histidine metabolism_Homo sapiens_hsa003402.13622790
8Nitrogen metabolism_Homo sapiens_hsa009102.05821550
9Phenylalanine metabolism_Homo sapiens_hsa003601.95781679
10Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.90318541
11Dorso-ventral axis formation_Homo sapiens_hsa043201.83518201
12Oxidative phosphorylation_Homo sapiens_hsa001901.78986589
13beta-Alanine metabolism_Homo sapiens_hsa004101.76721823
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.74898644
15Gastric acid secretion_Homo sapiens_hsa049711.72563632
16Mineral absorption_Homo sapiens_hsa049781.69992652
17Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.66838858
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.63030760
19Glycosaminoglycan degradation_Homo sapiens_hsa005311.58595865
20Amphetamine addiction_Homo sapiens_hsa050311.58279542
21Renin secretion_Homo sapiens_hsa049241.55630513
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54564893
23Tryptophan metabolism_Homo sapiens_hsa003801.54139396
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.52383410
25PPAR signaling pathway_Homo sapiens_hsa033201.47968320
26ABC transporters_Homo sapiens_hsa020101.45125626
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.44245155
28Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.41108848
29Caffeine metabolism_Homo sapiens_hsa002321.39295555
30Fatty acid biosynthesis_Homo sapiens_hsa000611.39071592
31Estrogen signaling pathway_Homo sapiens_hsa049151.38704097
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.35417926
33Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.34005435
34Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.32698260
35Intestinal immune network for IgA production_Homo sapiens_hsa046721.32462200
36Parkinsons disease_Homo sapiens_hsa050121.29326042
37Ether lipid metabolism_Homo sapiens_hsa005651.28717151
38Selenocompound metabolism_Homo sapiens_hsa004501.26722817
39Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.23391790
40Salivary secretion_Homo sapiens_hsa049701.20458742
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.19010995
42Peroxisome_Homo sapiens_hsa041461.18395428
43Glucagon signaling pathway_Homo sapiens_hsa049221.16606702
44Thyroid hormone synthesis_Homo sapiens_hsa049181.16140989
45Vascular smooth muscle contraction_Homo sapiens_hsa042701.12976394
46Taste transduction_Homo sapiens_hsa047421.12852073
47Glutathione metabolism_Homo sapiens_hsa004801.11387396
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.10355460
49Hedgehog signaling pathway_Homo sapiens_hsa043401.08889682
50Pyruvate metabolism_Homo sapiens_hsa006201.07842893
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.06961814
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.06540829
53Olfactory transduction_Homo sapiens_hsa047401.04181387
54Circadian entrainment_Homo sapiens_hsa047131.03628550
55ECM-receptor interaction_Homo sapiens_hsa045121.03365188
56Cardiac muscle contraction_Homo sapiens_hsa042601.00523153
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99449561
58Cocaine addiction_Homo sapiens_hsa050300.98090003
59Insulin secretion_Homo sapiens_hsa049110.97788816
60Nicotine addiction_Homo sapiens_hsa050330.96209236
61Asthma_Homo sapiens_hsa053100.95565719
62Glutamatergic synapse_Homo sapiens_hsa047240.94556158
63Serotonergic synapse_Homo sapiens_hsa047260.94369768
64Chemical carcinogenesis_Homo sapiens_hsa052040.92941736
65Propanoate metabolism_Homo sapiens_hsa006400.90765509
66GABAergic synapse_Homo sapiens_hsa047270.89996982
67Alzheimers disease_Homo sapiens_hsa050100.89826642
68Salmonella infection_Homo sapiens_hsa051320.89745755
69Linoleic acid metabolism_Homo sapiens_hsa005910.87951530
70Antigen processing and presentation_Homo sapiens_hsa046120.87617549
71Renal cell carcinoma_Homo sapiens_hsa052110.86646995
72Type I diabetes mellitus_Homo sapiens_hsa049400.85083959
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84781970
74Wnt signaling pathway_Homo sapiens_hsa043100.84495731
75Basal transcription factors_Homo sapiens_hsa030220.84397738
76Collecting duct acid secretion_Homo sapiens_hsa049660.84257794
77Graft-versus-host disease_Homo sapiens_hsa053320.83966624
78Malaria_Homo sapiens_hsa051440.83394699
79Calcium signaling pathway_Homo sapiens_hsa040200.83089700
80Butanoate metabolism_Homo sapiens_hsa006500.82893801
81Glycerolipid metabolism_Homo sapiens_hsa005610.82861019
82alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.82452582
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80783189
84Melanogenesis_Homo sapiens_hsa049160.80263847
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.79987953
86Axon guidance_Homo sapiens_hsa043600.79379166
87Protein export_Homo sapiens_hsa030600.78609157
88Allograft rejection_Homo sapiens_hsa053300.78331590
89cAMP signaling pathway_Homo sapiens_hsa040240.77934468
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.76970684
91Autoimmune thyroid disease_Homo sapiens_hsa053200.75832888
92Ovarian steroidogenesis_Homo sapiens_hsa049130.74777315
93Oxytocin signaling pathway_Homo sapiens_hsa049210.74640566
94Hippo signaling pathway_Homo sapiens_hsa043900.73891482
95Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73715345
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71525465
97Retinol metabolism_Homo sapiens_hsa008300.70142598
98Leukocyte transendothelial migration_Homo sapiens_hsa046700.69506650
99Circadian rhythm_Homo sapiens_hsa047100.69404561
100Basal cell carcinoma_Homo sapiens_hsa052170.67076926
101Platelet activation_Homo sapiens_hsa046110.66867998
102Tight junction_Homo sapiens_hsa045300.66592749
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65913560
104Regulation of autophagy_Homo sapiens_hsa041400.65334716
105Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64771523
106Ribosome_Homo sapiens_hsa030100.63925169
107Focal adhesion_Homo sapiens_hsa045100.63914024
108Fatty acid degradation_Homo sapiens_hsa000710.63782576
109Bile secretion_Homo sapiens_hsa049760.62764596
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62218109
111Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61596323
112B cell receptor signaling pathway_Homo sapiens_hsa046620.61321357
113Sphingolipid metabolism_Homo sapiens_hsa006000.61060168
114Pancreatic secretion_Homo sapiens_hsa049720.61036615
115Vitamin digestion and absorption_Homo sapiens_hsa049770.60883378
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.60479448
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.59699406
118Tyrosine metabolism_Homo sapiens_hsa003500.59554777
119Dilated cardiomyopathy_Homo sapiens_hsa054140.59347018
120Rheumatoid arthritis_Homo sapiens_hsa053230.58589423
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.58475630
122Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58338173
123Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56489492
124Phagosome_Homo sapiens_hsa041450.56269701
125Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55773323
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.55740735
127Arachidonic acid metabolism_Homo sapiens_hsa005900.55282169
128Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53407864
129Rap1 signaling pathway_Homo sapiens_hsa040150.53252494
130Protein digestion and absorption_Homo sapiens_hsa049740.53198644
131VEGF signaling pathway_Homo sapiens_hsa043700.53083772
132Metabolic pathways_Homo sapiens_hsa011000.52510133
133MAPK signaling pathway_Homo sapiens_hsa040100.52486832
134Glycerophospholipid metabolism_Homo sapiens_hsa005640.52276189
135Long-term potentiation_Homo sapiens_hsa047200.51874972
136Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.50846769
137Fat digestion and absorption_Homo sapiens_hsa049750.50750095
138Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50471189
139Fanconi anemia pathway_Homo sapiens_hsa034600.49450691
140Morphine addiction_Homo sapiens_hsa050320.49084067
141Osteoclast differentiation_Homo sapiens_hsa043800.48577559
142Gap junction_Homo sapiens_hsa045400.48016175
143Homologous recombination_Homo sapiens_hsa034400.47370473
144Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44824162
145Sulfur relay system_Homo sapiens_hsa041220.42739583
146RNA polymerase_Homo sapiens_hsa030200.41748049
147Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39053911
148Purine metabolism_Homo sapiens_hsa002300.38629784
149Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.38035064
150Steroid biosynthesis_Homo sapiens_hsa001000.37184881
151Drug metabolism - other enzymes_Homo sapiens_hsa009830.31594265

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