CDC42BPG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)5.96678015
2desmosome organization (GO:0002934)4.71329075
3regulation of hippo signaling (GO:0035330)4.68780098
4surfactant homeostasis (GO:0043129)4.42616970
5bundle of His cell to Purkinje myocyte communication (GO:0086069)4.33058667
6activation of Rac GTPase activity (GO:0032863)4.20057460
7positive regulation of Cdc42 GTPase activity (GO:0043089)4.15910901
8epithelial cell-cell adhesion (GO:0090136)4.10782950
9establishment of apical/basal cell polarity (GO:0035089)4.03943518
10cell-substrate junction assembly (GO:0007044)3.90547240
11semaphorin-plexin signaling pathway (GO:0071526)3.89378403
12regulation of water loss via skin (GO:0033561)3.82408115
13regulation of cholesterol homeostasis (GO:2000188)3.81445211
14COPI coating of Golgi vesicle (GO:0048205)3.81341825
15Golgi transport vesicle coating (GO:0048200)3.81341825
16regulation of interleukin-13 production (GO:0032656)3.79988556
17ear development (GO:0043583)3.75326247
18intestinal epithelial cell development (GO:0060576)3.73760735
19peptidyl-tyrosine autophosphorylation (GO:0038083)3.70366414
20cell adhesion mediated by integrin (GO:0033627)3.68140048
21polarized epithelial cell differentiation (GO:0030859)3.67258977
22regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.53327701
23regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.53325199
24positive regulation of epidermal cell differentiation (GO:0045606)3.52816285
25lung epithelium development (GO:0060428)3.52702203
26vitamin transmembrane transport (GO:0035461)3.50987288
27cytoskeletal anchoring at plasma membrane (GO:0007016)3.50457408
28positive regulation of keratinocyte differentiation (GO:0045618)3.49753718
29regulation of interleukin-5 production (GO:0032674)3.48400870
30regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.47560928
31mesodermal cell differentiation (GO:0048333)3.45386532
32calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.44526871
33keratinocyte proliferation (GO:0043616)3.43408185
34positive regulation of p38MAPK cascade (GO:1900745)3.42868998
35skin morphogenesis (GO:0043589)3.38641821
36establishment of skin barrier (GO:0061436)3.32179899
37negative regulation of keratinocyte proliferation (GO:0010839)3.29531011
38gap junction assembly (GO:0016264)3.26707482
39chemical homeostasis within a tissue (GO:0048875)3.26477560
40hormone catabolic process (GO:0042447)3.25799083
41renal filtration (GO:0097205)3.24764726
42endothelial cell chemotaxis (GO:0035767)3.24676904
43establishment or maintenance of monopolar cell polarity (GO:0061339)3.22353393
44establishment of monopolar cell polarity (GO:0061162)3.22353393
45glomerular visceral epithelial cell development (GO:0072015)3.21743619
46apical protein localization (GO:0045176)3.21518180
47regulation of fatty acid beta-oxidation (GO:0031998)3.20740738
48regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.16125367
49apoptotic process involved in morphogenesis (GO:0060561)3.15710585
50apoptotic cell clearance (GO:0043277)3.14682236
51atrioventricular valve morphogenesis (GO:0003181)3.14084454
52regulation of keratinocyte differentiation (GO:0045616)3.13359476
53multicellular organismal water homeostasis (GO:0050891)3.13263368
54proline biosynthetic process (GO:0006561)3.09956543
55hypotonic response (GO:0006971)3.07444324
56regulation of p38MAPK cascade (GO:1900744)3.06098051
57retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.04572793
58regulation of gene silencing by RNA (GO:0060966)3.04163190
59regulation of posttranscriptional gene silencing (GO:0060147)3.04163190
60regulation of gene silencing by miRNA (GO:0060964)3.04163190
61adherens junction assembly (GO:0034333)3.01347618
62trophectodermal cell differentiation (GO:0001829)3.01131041
63keratinization (GO:0031424)3.00057760
64glomerular epithelial cell development (GO:0072310)2.98984797
65negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.97025846
66negative regulation of cell size (GO:0045792)2.96402729
67virion attachment to host cell (GO:0019062)2.96231192
68adhesion of symbiont to host cell (GO:0044650)2.96231192
69epithelial cell differentiation involved in prostate gland development (GO:0060742)2.95774373
70protein localization to endosome (GO:0036010)2.94608171
71ectoderm development (GO:0007398)2.94298578
72cell migration involved in sprouting angiogenesis (GO:0002042)2.93642729
73striated muscle atrophy (GO:0014891)2.91788827
74positive regulation of fatty acid beta-oxidation (GO:0032000)2.91656598
75cell-cell junction assembly (GO:0007043)2.90342212
76asymmetric protein localization (GO:0008105)2.89682026
77hippo signaling (GO:0035329)2.89044536
78cell-cell junction maintenance (GO:0045217)2.86926322
79positive regulation of histone deacetylation (GO:0031065)2.85516984
80basement membrane organization (GO:0071711)2.85091135
81positive regulation of epidermis development (GO:0045684)2.84852776
82stress granule assembly (GO:0034063)2.84584735
83epidermal cell differentiation (GO:0009913)2.84464653
84cell-substrate adherens junction assembly (GO:0007045)2.83010619
85focal adhesion assembly (GO:0048041)2.83010619
86maternal placenta development (GO:0001893)2.81858785
87keratinocyte differentiation (GO:0030216)2.81248408
88intestinal cholesterol absorption (GO:0030299)2.79269952
89epidermis development (GO:0008544)2.79231909
90negative regulation of cell fate specification (GO:0009996)2.75011500
91phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.74042952
92respiratory tube development (GO:0030323)2.73930284
93endodermal cell differentiation (GO:0035987)2.73178013
94hair cycle (GO:0042633)2.70313772
95molting cycle (GO:0042303)2.70313772
96anterior/posterior axis specification, embryo (GO:0008595)2.69596572
97positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.68729612
98sulfur amino acid catabolic process (GO:0000098)2.68001051
99cysteine metabolic process (GO:0006534)2.67753330
100establishment of tissue polarity (GO:0007164)2.67408919
101establishment of planar polarity (GO:0001736)2.67408919
102blood vessel endothelial cell migration (GO:0043534)2.67407369
103embryonic eye morphogenesis (GO:0048048)2.67173349
104protein autoprocessing (GO:0016540)2.67159342
105negative regulation of viral release from host cell (GO:1902187)2.66309179
106cell differentiation involved in embryonic placenta development (GO:0060706)2.66213489
107water homeostasis (GO:0030104)2.65459995
108wound healing, spreading of epidermal cells (GO:0035313)2.63540324
109ventricular cardiac muscle cell action potential (GO:0086005)2.63305058
110regulation of ruffle assembly (GO:1900027)2.63149324
111regulation of establishment or maintenance of cell polarity (GO:0032878)2.62431035
112positive regulation of SMAD protein import into nucleus (GO:0060391)2.62265608
113regulation of cholesterol biosynthetic process (GO:0045540)2.62147857
114skeletal muscle adaptation (GO:0043501)2.61421772
115protein retention in ER lumen (GO:0006621)2.60531742
116regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.60455214
1174-hydroxyproline metabolic process (GO:0019471)2.59837905
118establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.59695070
119adhesion of symbiont to host (GO:0044406)2.59619008
120O-glycan processing (GO:0016266)2.58017544
121interferon-gamma secretion (GO:0072643)2.57645626
122regulation of glucose import in response to insulin stimulus (GO:2001273)2.57358495
123peptide catabolic process (GO:0043171)2.56572279
124tight junction assembly (GO:0070830)2.56203320
125glomerular basement membrane development (GO:0032836)2.56151114
126renal system development (GO:0072001)2.55407928
127regulation of viral release from host cell (GO:1902186)2.55159273
128intestinal absorption (GO:0050892)2.54719791
129proline metabolic process (GO:0006560)2.54532436
130maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.54145283
131morphogenesis of embryonic epithelium (GO:0016331)2.52817287
132cell junction maintenance (GO:0034331)2.51612034
133low-density lipoprotein particle clearance (GO:0034383)2.51518956
134amyloid precursor protein metabolic process (GO:0042982)2.51273266
135embryonic foregut morphogenesis (GO:0048617)2.51230886
136axonemal dynein complex assembly (GO:0070286)2.51216476
137primary alcohol catabolic process (GO:0034310)2.51065226
138receptor catabolic process (GO:0032801)2.50964204
139regulation of Cdc42 GTPase activity (GO:0043088)2.50010798
140establishment of epithelial cell polarity (GO:0090162)2.49967386
141vascular endothelial growth factor signaling pathway (GO:0038084)2.49391674
142regulation of keratinocyte proliferation (GO:0010837)2.48118969
143branching involved in mammary gland duct morphogenesis (GO:0060444)2.47957142
144planar cell polarity pathway involved in neural tube closure (GO:0090179)2.47646052
145peptide cross-linking (GO:0018149)2.47206672
146branching involved in salivary gland morphogenesis (GO:0060445)2.46698271
147regulation of cell fate specification (GO:0042659)2.46247085
148dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.45863948
149heterochromatin organization (GO:0070828)2.44761951
150paraxial mesoderm development (GO:0048339)2.44307924
151embryonic placenta development (GO:0001892)2.44161256
152epoxygenase P450 pathway (GO:0019373)2.43876003
153activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.42035350
154collecting duct development (GO:0072044)2.41282035
155regulation of SMAD protein import into nucleus (GO:0060390)2.38505734
156lung vasculature development (GO:0060426)2.37368030
157drug catabolic process (GO:0042737)2.37180312
158regulation of endothelial cell chemotaxis (GO:2001026)2.35641217
159lung-associated mesenchyme development (GO:0060484)2.34699686
160regulation of translational fidelity (GO:0006450)2.34599491
161phosphate ion transmembrane transport (GO:0035435)2.34050197
162establishment or maintenance of bipolar cell polarity (GO:0061245)2.33821256
163establishment or maintenance of apical/basal cell polarity (GO:0035088)2.33821256

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.97546084
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.65965890
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.63910806
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.59964462
5RARG_19884340_ChIP-ChIP_MEFs_Mouse2.58446390
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.48495198
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.45977708
8ESR2_21235772_ChIP-Seq_MCF-7_Human2.43890134
9ZNF263_19887448_ChIP-Seq_K562_Human2.41163961
10CLOCK_20551151_ChIP-Seq_293T_Human2.30342155
11ESR1_21235772_ChIP-Seq_MCF-7_Human2.30060817
12PPARA_22158963_ChIP-Seq_LIVER_Mouse2.20852199
13RXR_22158963_ChIP-Seq_LIVER_Mouse2.08835426
14* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.98343473
15KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.96700682
16KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.96700682
17KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.96700682
18SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.94001542
19NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.93751789
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.92465641
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.92447274
22* RACK7_27058665_Chip-Seq_MCF-7_Human1.90867031
23SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.90835743
24FOXO3_23340844_ChIP-Seq_DLD1_Human1.90737499
25LXR_22158963_ChIP-Seq_LIVER_Mouse1.88600784
26HIF1A_21447827_ChIP-Seq_MCF-7_Human1.87081706
27SOX2_27498859_Chip-Seq_STOMACH_Mouse1.86957018
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.82905430
29EGR1_19374776_ChIP-ChIP_THP-1_Human1.77734118
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.77122085
31CDX2_20551321_ChIP-Seq_CACO-2_Human1.70646419
32* ATF3_27146783_Chip-Seq_COLON_Human1.70266340
33* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.69061102
34SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.68134257
35ERG_21242973_ChIP-ChIP_JURKAT_Human1.67996885
36TCF3_18692474_ChIP-Seq_MEFs_Mouse1.65787811
37* GATA6_25053715_ChIP-Seq_YYC3_Human1.65588511
38* ELK3_25401928_ChIP-Seq_HUVEC_Human1.65054629
39ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.61784458
40SMC4_20622854_ChIP-Seq_HELA_Human1.61170924
41NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.59587226
42ESR1_15608294_ChIP-ChIP_MCF-7_Human1.57523947
43SOX9_24532713_ChIP-Seq_HFSC_Mouse1.57092591
44* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.56285520
45STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55608228
46* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.52932866
47* LXR_22292898_ChIP-Seq_THP-1_Human1.52737428
48RUNX1_27514584_Chip-Seq_MCF-7_Human1.52546301
49SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.48294394
50* P68_20966046_ChIP-Seq_HELA_Human1.47503514
51* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.46701336
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.46285119
53ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.45445160
54GATA4_25053715_ChIP-Seq_YYC3_Human1.44142848
55* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.44009821
56VDR_21846776_ChIP-Seq_THP-1_Human1.43813572
57* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.42909145
58* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.42909145
59P300_27058665_Chip-Seq_ZR-75-30cells_Human1.42620383
60PPAR_26484153_Chip-Seq_NCI-H1993_Human1.42434361
61RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.41575379
62KDM2B_26808549_Chip-Seq_SUP-B15_Human1.40961054
63NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.37248598
64KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.35048971
65KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.30310581
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.27792171
67CTCF_27219007_Chip-Seq_Bcells_Human1.27629871
68SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.26457972
69ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.26204175
70KDM2B_26808549_Chip-Seq_DND41_Human1.26025775
71* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.25744524
72CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.25453020
73ZFP281_18757296_ChIP-ChIP_E14_Mouse1.24267823
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.23796506
75ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.23360654
76TCF7_22412390_ChIP-Seq_EML_Mouse1.23259004
77SA1_27219007_Chip-Seq_ERYTHROID_Human1.23094307
78* TET1_21451524_ChIP-Seq_MESCs_Mouse1.22921422
79RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.22448980
80KDM2B_26808549_Chip-Seq_K562_Human1.21988897
81AHR_22903824_ChIP-Seq_MCF-7_Human1.21331289
82ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.19391458
83TCF3_18692474_ChIP-Seq_MESCs_Mouse1.18977412
84NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.17053002
85ZFP281_27345836_Chip-Seq_ESCs_Mouse1.16201856
86MYC_22102868_ChIP-Seq_BL_Human1.16037090
87KLF5_25053715_ChIP-Seq_YYC3_Human1.15257209
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13906590
89ESR1_20079471_ChIP-ChIP_T-47D_Human1.12922654
90FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.12863252
91* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.12611548
92CREB1_26743006_Chip-Seq_LNCaP_Human1.12076497
93TP53_22127205_ChIP-Seq_IMR90_Human1.11260571
94SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10721154
95TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10087718
96SOX2_20726797_ChIP-Seq_SW620_Human1.09749520
97SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09300525
98SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08258406
99* NCOR1_26117541_ChIP-Seq_K562_Human1.07965934
100TBX20_22328084_ChIP-Seq_HEART_Mouse1.07324226
101TBX20_22080862_ChIP-Seq_HEART_Mouse1.07324226
102NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.07294728
103UBF1/2_26484160_Chip-Seq_HMECs_Human1.05702817
104NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.05596119
105* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04884637
106* BCOR_27268052_Chip-Seq_Bcells_Human1.04584785
107DROSHA_22980978_ChIP-Seq_HELA_Human1.04254909
108KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04179483
109FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.03567345
110TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03496778
111TET1_21490601_ChIP-Seq_MESCs_Mouse1.02340391
112* SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.02031624
113STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01906138
114EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01824912
115* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01415205
116DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99296316
117GATA2_21666600_ChIP-Seq_HMVEC_Human0.98299951
118KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97937645
119TP63_22573176_ChIP-Seq_HFKS_Human0.97483048
120GATA3_24758297_ChIP-Seq_MCF-7_Human0.97189395
121CHD1_26751641_Chip-Seq_LNCaP_Human0.96917734
122* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96871935
123EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96277133
124NANOG_18692474_ChIP-Seq_MEFs_Mouse0.95668315
125RARB_24833708_ChIP-Seq_LIVER_Mouse0.95433463
126BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.95320600
127WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.95215011
128* FOXA2_19822575_ChIP-Seq_HepG2_Human0.94353508
129FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92981753
130* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.90566981

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.73701792
2MP0003705_abnormal_hypodermis_morpholog4.25841797
3MP0000566_synostosis3.61099487
4MP0002796_impaired_skin_barrier3.45184852
5MP0005275_abnormal_skin_tensile2.96667430
6MP0010352_gastrointestinal_tract_polyps2.66458761
7MP0000537_abnormal_urethra_morphology2.65893789
8MP0003566_abnormal_cell_adhesion2.60475813
9MP0004381_abnormal_hair_follicle2.39563332
10MP0002254_reproductive_system_inflammat2.31456929
11MP0005409_darkened_coat_color2.31175162
12MP0004264_abnormal_extraembryonic_tissu2.30950037
13MP0005501_abnormal_skin_physiology2.24377918
14MP0001849_ear_inflammation2.11487468
15MP0000678_abnormal_parathyroid_gland2.09689211
16MP0005360_urolithiasis2.06458706
17MP0003453_abnormal_keratinocyte_physiol2.04036456
18MP0004272_abnormal_basement_membrane2.02809253
19MP0002060_abnormal_skin_morphology1.95061992
20MP0000579_abnormal_nail_morphology1.88891217
21MP0009780_abnormal_chondrocyte_physiolo1.83982769
22MP0005076_abnormal_cell_differentiation1.81837321
23MP0003283_abnormal_digestive_organ1.77039453
24MP0005377_hearing/vestibular/ear_phenot1.76943476
25MP0003878_abnormal_ear_physiology1.76943476
26MP0003300_gastrointestinal_ulcer1.75888939
27MP0005023_abnormal_wound_healing1.68317808
28MP0003941_abnormal_skin_development1.67730542
29MP0002877_abnormal_melanocyte_morpholog1.65487600
30MP0010678_abnormal_skin_adnexa1.65241900
31MP0004185_abnormal_adipocyte_glucose1.64412491
32MP0001216_abnormal_epidermal_layer1.62720141
33MP0002139_abnormal_hepatobiliary_system1.58553825
34MP0005451_abnormal_body_composition1.55903002
35MP0005083_abnormal_biliary_tract1.55865360
36MP0001958_emphysema1.55036459
37MP0004782_abnormal_surfactant_physiolog1.53231260
38MP0002098_abnormal_vibrissa_morphology1.51285709
39MP0002249_abnormal_larynx_morphology1.48883338
40MP0001666_abnormal_nutrient_absorption1.48080659
41MP0004947_skin_inflammation1.45773287
42MP0008438_abnormal_cutaneous_collagen1.42640893
43MP0009379_abnormal_foot_pigmentation1.41620787
44MP0000467_abnormal_esophagus_morphology1.40596090
45MP0005085_abnormal_gallbladder_physiolo1.38556009
46MP0003191_abnormal_cellular_cholesterol1.36762636
47MP0003252_abnormal_bile_duct1.32326083
48MP0010030_abnormal_orbit_morphology1.24658863
49MP0005365_abnormal_bile_salt1.23837917
50MP0009053_abnormal_anal_canal1.20443978
51MP0005623_abnormal_meninges_morphology1.17738839
52MP0010771_integument_phenotype1.16819224
53MP0000762_abnormal_tongue_morphology1.16330592
54MP0001873_stomach_inflammation1.15663491
55MP0001765_abnormal_ion_homeostasis1.15468530
56MP0000427_abnormal_hair_cycle1.14348885
57MP0000377_abnormal_hair_follicle1.14035286
58MP0002138_abnormal_hepatobiliary_system1.12149547
59MP0008961_abnormal_basal_metabolism1.11924875
60MP0009643_abnormal_urine_homeostasis1.10327165
61MP0005167_abnormal_blood-brain_barrier1.08593343
62MP0000462_abnormal_digestive_system1.08094979
63MP0009840_abnormal_foam_cell1.07075251
64MP0002089_abnormal_postnatal_growth/wei1.05997926
65MP0002234_abnormal_pharynx_morphology1.05557329
66MP0000383_abnormal_hair_follicle1.04885674
67MP0008875_abnormal_xenobiotic_pharmacok1.04803130
68MP0001348_abnormal_lacrimal_gland1.02027262
69MP0000367_abnormal_coat/_hair1.01813094
70MP0003115_abnormal_respiratory_system1.00974938
71MP0010368_abnormal_lymphatic_system1.00562949
72MP0003045_fibrosis0.99705318
73MP0000534_abnormal_ureter_morphology0.98120590
74MP0005666_abnormal_adipose_tissue0.97396466
75MP0003091_abnormal_cell_migration0.97371696
76MP0003806_abnormal_nucleotide_metabolis0.95779783
77MP0001664_abnormal_digestion0.91439100
78MP0000477_abnormal_intestine_morphology0.90988190
79MP0002086_abnormal_extraembryonic_tissu0.89899328
80MP0009931_abnormal_skin_appearance0.89586523
81MP0004084_abnormal_cardiac_muscle0.89456079
82MP0003123_paternal_imprinting0.89339737
83MP0004019_abnormal_vitamin_homeostasis0.86893021
84MP0003119_abnormal_digestive_system0.86632349
85MP0002136_abnormal_kidney_physiology0.86254912
86MP0000733_abnormal_muscle_development0.86177401
87MP0006054_spinal_hemorrhage0.85800058
88MP0004043_abnormal_pH_regulation0.83351261
89MP0003183_abnormal_peptide_metabolism0.82413413
90MP0009384_cardiac_valve_regurgitation0.81496856
91MP0005367_renal/urinary_system_phenotyp0.80819186
92MP0000516_abnormal_urinary_system0.80819186
93MP0004197_abnormal_fetal_growth/weight/0.80095653
94MP0005058_abnormal_lysosome_morphology0.80016123
95MP0001881_abnormal_mammary_gland0.78879183
96MP0002909_abnormal_adrenal_gland0.78833631
97MP0002925_abnormal_cardiovascular_devel0.78377859
98MP0001243_abnormal_dermal_layer0.78357107
99MP0000627_abnormal_mammary_gland0.78019664
100MP0003866_abnormal_defecation0.77588732
101MP0005375_adipose_tissue_phenotype0.77301283
102MP0003879_abnormal_hair_cell0.75934568
103MP0002084_abnormal_developmental_patter0.75826621
104MP0001346_abnormal_lacrimal_gland0.75417413
105MP0000647_abnormal_sebaceous_gland0.75182496
106MP0001191_abnormal_skin_condition0.75037123
107MP0010329_abnormal_lipoprotein_level0.74948067
108MP0002896_abnormal_bone_mineralization0.74840267
109MP0005332_abnormal_amino_acid0.74085721
110MP0001756_abnormal_urination0.71729390
111MP0008260_abnormal_autophagy0.69952658
112MP0002166_altered_tumor_susceptibility0.69514456
113MP0010630_abnormal_cardiac_muscle0.68116211
114MP0002295_abnormal_pulmonary_circulatio0.67660948
115MP0004858_abnormal_nervous_system0.66664455
116MP0000609_abnormal_liver_physiology0.65810529
117MP0000003_abnormal_adipose_tissue0.65526619
118MP0002088_abnormal_embryonic_growth/wei0.65334749
119MP0003984_embryonic_growth_retardation0.65123230
120MP0002697_abnormal_eye_size0.64938164
121MP0001730_embryonic_growth_arrest0.64875715
122MP0001672_abnormal_embryogenesis/_devel0.64580946
123MP0005380_embryogenesis_phenotype0.64580946
124MP0009278_abnormal_bone_marrow0.63590528
125MP0000470_abnormal_stomach_morphology0.63258626
126MP0001784_abnormal_fluid_regulation0.62931430
127MP0000858_altered_metastatic_potential0.62377436
128MP0010155_abnormal_intestine_physiology0.61649916
129MP0002085_abnormal_embryonic_tissue0.61309481
130MP0002111_abnormal_tail_morphology0.60897257
131MP0003638_abnormal_response/metabolism_0.59342417
132MP0000681_abnormal_thyroid_gland0.59077920
133MP0009672_abnormal_birth_weight0.58529548
134MP0002653_abnormal_ependyma_morphology0.57764387
135MP0004233_abnormal_muscle_weight0.57599826
136MP0005670_abnormal_white_adipose0.56300026
137MP0005257_abnormal_intraocular_pressure0.54052334
138MP0002009_preneoplasia0.53370088
139MP0000490_abnormal_crypts_of0.53274168
140MP0003936_abnormal_reproductive_system0.53221964
141MP0005636_abnormal_mineral_homeostasis0.52002724
142MP0005248_abnormal_Harderian_gland0.51189743
143MP0006138_congestive_heart_failure0.49702506
144MP0005310_abnormal_salivary_gland0.48681242

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)4.81688287
2Milia (HP:0001056)4.24094719
3Atrophic scars (HP:0001075)4.00179297
4Interstitial pulmonary disease (HP:0006530)3.92336795
5Onycholysis (HP:0001806)3.64081708
6Pili torti (HP:0003777)3.48185549
7Lip pit (HP:0100267)3.37003471
8Cerebral aneurysm (HP:0004944)3.30584827
9Dysmetric saccades (HP:0000641)3.28115680
10Plantar hyperkeratosis (HP:0007556)3.21037631
11Fragile nails (HP:0001808)3.14781665
12Chronic bronchitis (HP:0004469)3.10574924
13Hyperactive renin-angiotensin system (HP:0000841)3.07754977
14Focal segmental glomerulosclerosis (HP:0000097)3.01520277
15Amelogenesis imperfecta (HP:0000705)3.01288167
16Obstructive sleep apnea (HP:0002870)2.94414307
17Broad face (HP:0000283)2.93842274
18Shallow orbits (HP:0000586)2.85348374
19Septate vagina (HP:0001153)2.83807418
20Ulnar bowing (HP:0003031)2.81779282
21Woolly hair (HP:0002224)2.81430630
22Thick nail (HP:0001805)2.80676845
23Congenital ichthyosiform erythroderma (HP:0007431)2.78440083
24Glomerulosclerosis (HP:0000096)2.77858021
25Increased connective tissue (HP:0009025)2.65146572
26Nail dystrophy (HP:0008404)2.60503404
27Esophageal varix (HP:0002040)2.58249063
28Gout (HP:0001997)2.55478797
29Germ cell neoplasia (HP:0100728)2.55094455
30Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.54813288
31Hypotrichosis (HP:0001006)2.53431488
32Abnormality of the dental root (HP:0006486)2.43460828
33Taurodontia (HP:0000679)2.43460828
34Abnormality of permanent molar morphology (HP:0011071)2.43460828
35Fragile skin (HP:0001030)2.42216915
36Alopecia of scalp (HP:0002293)2.40296926
37Aneurysm (HP:0002617)2.38671483
38Flat acetabular roof (HP:0003180)2.35503016
39Bowed forearm bones (HP:0003956)2.35120800
40Bowing of the arm (HP:0006488)2.35120800
41Hyperacusis (HP:0010780)2.34933662
42Protrusio acetabuli (HP:0003179)2.34631334
43Hand muscle atrophy (HP:0009130)2.34417987
44Distal upper limb amyotrophy (HP:0007149)2.31962805
45Upper limb amyotrophy (HP:0009129)2.31962805
46Abnormal hair laboratory examination (HP:0003328)2.31631848
47Pterygium (HP:0001059)2.30308525
48Malnutrition (HP:0004395)2.29873380
49Ridged nail (HP:0001807)2.29797054
50Palmoplantar hyperkeratosis (HP:0000972)2.29429458
51Rectal prolapse (HP:0002035)2.24451590
52Mildly elevated creatine phosphokinase (HP:0008180)2.22677492
53Abnormality of molar morphology (HP:0011070)2.22404497
54Abnormality of molar (HP:0011077)2.22404497
55J-shaped sella turcica (HP:0002680)2.21859938
56Deep venous thrombosis (HP:0002625)2.21504355
57Bronchomalacia (HP:0002780)2.21264200
58Turricephaly (HP:0000262)2.20082852
59Lymphangioma (HP:0100764)2.19526527
60Ventricular tachycardia (HP:0004756)2.18524651
61Hyporeflexia of lower limbs (HP:0002600)2.18344108
62Hyperparathyroidism (HP:0000843)2.17905917
63Abnormality of chloride homeostasis (HP:0011422)2.17074483
64Selective tooth agenesis (HP:0001592)2.16248994
65Natal tooth (HP:0000695)2.16061028
66Palmar hyperkeratosis (HP:0010765)2.14599810
67Abnormality of the dental pulp (HP:0006479)2.13713461
68Broad metatarsal (HP:0001783)2.11908825
69Ankyloglossia (HP:0010296)2.10597538
70Curly hair (HP:0002212)2.10444288
71Abnormality of the gastric mucosa (HP:0004295)2.09709511
72Nasal polyposis (HP:0100582)2.09481408
73Premature rupture of membranes (HP:0001788)2.09319176
74Asymmetry of the thorax (HP:0001555)2.06991756
75Ankle contracture (HP:0006466)2.06702669
76Abnormality of glutamine family amino acid metabolism (HP:0010902)2.06466301
77Thin bony cortex (HP:0002753)2.02714913
78Radial bowing (HP:0002986)2.02193705
79Abnormality of the fingertips (HP:0001211)2.01933835
80Abnormal blistering of the skin (HP:0008066)2.01717336
81Polycythemia (HP:0001901)2.01605583
82Micronodular cirrhosis (HP:0001413)1.96970043
83Seborrheic dermatitis (HP:0001051)1.95984723
84Sparse eyelashes (HP:0000653)1.95229560
85Hematochezia (HP:0002573)1.94699970
86Abnormality of proline metabolism (HP:0010907)1.94355731
87Hydroxyprolinuria (HP:0003080)1.94355731
88Hyperkalemia (HP:0002153)1.94168352
89Cervical subluxation (HP:0003308)1.93683139
90Sparse scalp hair (HP:0002209)1.93567864
91Erythema (HP:0010783)1.92276695
92Back pain (HP:0003418)1.92038113
93Renal salt wasting (HP:0000127)1.91970385
94Aortic aneurysm (HP:0004942)1.91628510
95Stridor (HP:0010307)1.90928099
96Abnormal respiratory motile cilium physiology (HP:0012261)1.90665557
97Short humerus (HP:0005792)1.89860169
98Corneal erosion (HP:0200020)1.89495363
99Mitral valve prolapse (HP:0001634)1.88699922
100Shawl scrotum (HP:0000049)1.88578395
101Distal lower limb amyotrophy (HP:0008944)1.88259968
102Abnormality of nail color (HP:0100643)1.86584814
103Oligodontia (HP:0000677)1.84833934
104Spastic diplegia (HP:0001264)1.84301611
105Esophageal atresia (HP:0002032)1.83593144
106Sparse lateral eyebrow (HP:0005338)1.83051036
107Short nail (HP:0001799)1.81625699
108Visceral angiomatosis (HP:0100761)1.80931635
109Spinal cord compression (HP:0002176)1.80909007
110Biliary tract neoplasm (HP:0100574)1.80512172
111Hypoplasia of dental enamel (HP:0006297)1.80466379
112Abnormal vertebral ossification (HP:0100569)1.80433909
113Abdominal distention (HP:0003270)1.79898270
114Abnormality of monocarboxylic acid metabolism (HP:0010996)1.79532579
115Distal lower limb muscle weakness (HP:0009053)1.79164159
116Abnormality of the Achilles tendon (HP:0005109)1.78703796
117Absent eyelashes (HP:0000561)1.78208698
118Metaphyseal cupping (HP:0003021)1.77414413
119Achilles tendon contracture (HP:0001771)1.76526598
120Abnormality of renin-angiotensin system (HP:0000847)1.76204371
121Mesangial abnormality (HP:0001966)1.75661285
122Abnormality of the nasal mucosa (HP:0000433)1.75406133
123Ependymoma (HP:0002888)1.74692116
124Abnormality of the distal phalanges of the toes (HP:0010182)1.74495015
125Abnormal cartilage morphology (HP:0002763)1.74445692
126Progressive sensorineural hearing impairment (HP:0000408)1.74375825
127Popliteal pterygium (HP:0009756)1.73685430
128Subacute progressive viral hepatitis (HP:0006572)1.72902685
129Pustule (HP:0200039)1.72742504
130Diaphragmatic weakness (HP:0009113)1.72334765
131Atelectasis (HP:0100750)1.72238851
132Abnormality of purine metabolism (HP:0004352)1.72199863
133Dehydration (HP:0001944)1.71972308
134Abnormal respiratory motile cilium morphology (HP:0005938)1.71950794
135Abnormal respiratory epithelium morphology (HP:0012253)1.71950794
136Neonatal death (HP:0003811)1.71452512
137Increased IgE level (HP:0003212)1.70823851
138Pseudobulbar signs (HP:0002200)1.70653357
139Difficulty climbing stairs (HP:0003551)1.69724571
140Hypoplastic labia majora (HP:0000059)1.69218816
141Abnormality of the salivary glands (HP:0010286)1.68928275
142Rhinitis (HP:0012384)1.68185097
143Absent/shortened dynein arms (HP:0200106)1.67964797
144Dynein arm defect of respiratory motile cilia (HP:0012255)1.67964797
145Hemangiomatosis (HP:0007461)1.67725155
146Hamartoma of the eye (HP:0010568)1.66925881
147Abnormal ciliary motility (HP:0012262)1.66769990
148Peritonitis (HP:0002586)1.64991123
149Abnormality of the distal phalanx of the thumb (HP:0009617)1.64395606
150Advanced eruption of teeth (HP:0006288)1.64239730
151Gastrointestinal carcinoma (HP:0002672)1.63486529
152Malignant gastrointestinal tract tumors (HP:0006749)1.63486529
153Hemorrhage of the eye (HP:0011885)1.61342602
154Acanthosis nigricans (HP:0000956)1.60719283
155Aplasia/hypoplasia of the humerus (HP:0006507)1.60530584
156Xanthomatosis (HP:0000991)1.59852668

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA25.17791690
2ERN13.27266586
3TRIB33.23939556
4SMG13.21804781
5RIPK12.87212077
6CDK122.73534692
7LATS12.64126507
8PKN22.55012977
9PTK62.14937151
10TTN2.11616784
11EEF2K2.07827347
12PAK41.91256848
13PDGFRA1.84953873
14FER1.77761189
15RPS6KB21.75817520
16SIK11.74876712
17FGFR41.74669665
18EPHB11.74430213
19PTK21.71464940
20MST1R1.67221058
21LRRK21.65116876
22MAPKAPK31.63317633
23EPHB21.59327861
24STK101.53377290
25IRAK31.50380851
26TGFBR21.48567776
27NME11.47626507
28DDR21.46674095
29BMX1.46125632
30MAP3K101.45489704
31MET1.42964124
32MST41.40234212
33MAP3K31.38958172
34ICK1.34068704
35MAP3K21.22536282
36MTOR1.14055165
37MAP2K21.11571319
38MAP3K61.10412444
39MARK21.05559286
40PRPF4B1.04150557
41TNK21.03603640
42CDK61.00148013
43NME20.97485107
44DYRK1B0.96937625
45LATS20.96933443
46FRK0.96928409
47MAP3K70.94676491
48STK38L0.94331175
49NEK60.90870733
50EPHA30.88270446
51PRKCI0.87057855
52MUSK0.86939376
53PAK20.83874601
54STK30.83079528
55RPS6KA20.82880990
56LMTK20.81125392
57WNK40.80983292
58PDGFRB0.78973295
59FGFR10.78924011
60AKT30.75832033
61BCKDK0.75398119
62FLT30.75287360
63PDPK10.74597326
64MAP2K30.74129058
65TYRO30.73320806
66NEK10.72934861
67GRK60.72206047
68ALK0.70910121
69MATK0.69738863
70TESK10.69457857
71TIE10.69447534
72CSK0.69212318
73CAMK1D0.68814984
74PRKG20.68359411
75TRPM70.68048719
76ERBB40.67014847
77FGFR20.66472599
78GSK3A0.65951303
79TAOK10.64512012
80TAOK30.63853476
81MAP2K10.63228432
82DMPK0.63168997
83MAP3K80.62460524
84OXSR10.60225355
85STK380.59292272
86HIPK20.59146404
87PAK30.57028400
88CHUK0.55130346
89IRAK20.52759542
90ERBB20.52618156
91STK390.51733861
92NEK20.51581286
93FGFR30.50960101
94SCYL20.50924831
95PRKD10.50231094
96WNK10.49980786
97MAP2K60.48687146
98STK240.47256136
99CDK70.45945486
100CAMK1G0.45015827
101MAP3K90.44480343
102KSR20.44440119
103PRKAA20.44350007
104RET0.44029347
105MAP3K10.43952681
106TTK0.43887294
107TGFBR10.42679154
108PIK3CA0.42597634
109AKT20.41435874
110EGFR0.41368311
111RPS6KL10.41004966
112RPS6KC10.41004966
113TESK20.39691649
114PRKD20.38309587
115CDK40.35358593
116NTRK10.34159639
117CDC42BPA0.34158856
118MAPK150.33421313
119PIM20.32905533
120RPS6KA10.32780909
121MAPK110.32004910
122DAPK30.31592850
123JAK20.30152636
124PRKD30.29475282
125RPS6KB10.28575284
126MAPKAPK20.28444343
127ARAF0.27347761
128RPS6KA60.26596933
129SIK30.25820455
130MAPK80.25294649
131TBK10.23623408
132CDK90.22346403
133ILK0.21834553
134MELK0.21174658

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.36777884
2Adherens junction_Homo sapiens_hsa045202.02200172
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.01972669
4Bladder cancer_Homo sapiens_hsa052191.98764799
5Small cell lung cancer_Homo sapiens_hsa052221.90444299
6Phenylalanine metabolism_Homo sapiens_hsa003601.87724080
7Protein digestion and absorption_Homo sapiens_hsa049741.76503118
8Cyanoamino acid metabolism_Homo sapiens_hsa004601.72992171
9Fat digestion and absorption_Homo sapiens_hsa049751.70393970
10Focal adhesion_Homo sapiens_hsa045101.68890974
11Tight junction_Homo sapiens_hsa045301.67624299
12Nitrogen metabolism_Homo sapiens_hsa009101.66391946
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.60341775
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.59516841
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.58975040
16Fatty acid degradation_Homo sapiens_hsa000711.58734551
17Sphingolipid metabolism_Homo sapiens_hsa006001.55451368
18Hippo signaling pathway_Homo sapiens_hsa043901.54166021
19Caffeine metabolism_Homo sapiens_hsa002321.53363508
20Bile secretion_Homo sapiens_hsa049761.52014460
21Tryptophan metabolism_Homo sapiens_hsa003801.51881398
22Lysine degradation_Homo sapiens_hsa003101.51195288
23Proteoglycans in cancer_Homo sapiens_hsa052051.50560034
24Amoebiasis_Homo sapiens_hsa051461.50451453
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49707973
26Selenocompound metabolism_Homo sapiens_hsa004501.49664166
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.47743369
28Other glycan degradation_Homo sapiens_hsa005111.46535885
29Arginine biosynthesis_Homo sapiens_hsa002201.29429024
30Pentose and glucuronate interconversions_Homo sapiens_hsa000401.28874265
31Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.28337211
32Mineral absorption_Homo sapiens_hsa049781.27561107
33Basal cell carcinoma_Homo sapiens_hsa052171.24399620
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.24046327
35Phosphatidylinositol signaling system_Homo sapiens_hsa040701.22859289
36Renin-angiotensin system_Homo sapiens_hsa046141.22564112
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.22237973
38Choline metabolism in cancer_Homo sapiens_hsa052311.21917878
39Insulin signaling pathway_Homo sapiens_hsa049101.21775745
40PPAR signaling pathway_Homo sapiens_hsa033201.20269894
41ErbB signaling pathway_Homo sapiens_hsa040121.19098965
42Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.19060213
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.18267407
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11075270
45Thyroid cancer_Homo sapiens_hsa052161.07971410
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04719969
47GnRH signaling pathway_Homo sapiens_hsa049121.04551238
48Inositol phosphate metabolism_Homo sapiens_hsa005621.04289606
49Insulin resistance_Homo sapiens_hsa049311.03396398
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.02251261
51mTOR signaling pathway_Homo sapiens_hsa041501.02057963
52Renal cell carcinoma_Homo sapiens_hsa052111.01744695
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01202585
54MicroRNAs in cancer_Homo sapiens_hsa052061.00059097
55Glycerophospholipid metabolism_Homo sapiens_hsa005640.97937406
56Fructose and mannose metabolism_Homo sapiens_hsa000510.97515924
57Chemical carcinogenesis_Homo sapiens_hsa052040.94599941
58Notch signaling pathway_Homo sapiens_hsa043300.93431588
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.92639086
60Non-small cell lung cancer_Homo sapiens_hsa052230.92053569
61Chronic myeloid leukemia_Homo sapiens_hsa052200.90280222
62Estrogen signaling pathway_Homo sapiens_hsa049150.90011873
63ABC transporters_Homo sapiens_hsa020100.89578200
64Fatty acid metabolism_Homo sapiens_hsa012120.89572884
65Fatty acid biosynthesis_Homo sapiens_hsa000610.89556488
66Carbon metabolism_Homo sapiens_hsa012000.88539108
67Tyrosine metabolism_Homo sapiens_hsa003500.88271799
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86992526
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86867684
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.86857232
71Sulfur metabolism_Homo sapiens_hsa009200.86759304
72Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.85193976
73Starch and sucrose metabolism_Homo sapiens_hsa005000.84994384
74Hedgehog signaling pathway_Homo sapiens_hsa043400.84387726
75Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.83164427
76Endometrial cancer_Homo sapiens_hsa052130.82630549
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82484567
78Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82313200
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82275036
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81017503
81Biosynthesis of amino acids_Homo sapiens_hsa012300.79065730
82Vibrio cholerae infection_Homo sapiens_hsa051100.78705548
83Toxoplasmosis_Homo sapiens_hsa051450.78252617
84Axon guidance_Homo sapiens_hsa043600.77132850
85Histidine metabolism_Homo sapiens_hsa003400.76018660
86Complement and coagulation cascades_Homo sapiens_hsa046100.75892062
87VEGF signaling pathway_Homo sapiens_hsa043700.74506383
88Dilated cardiomyopathy_Homo sapiens_hsa054140.74220240
89N-Glycan biosynthesis_Homo sapiens_hsa005100.74166299
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73960519
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.72841350
92Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.72619189
93Glutathione metabolism_Homo sapiens_hsa004800.72549541
94Pentose phosphate pathway_Homo sapiens_hsa000300.71002562
95Glycerolipid metabolism_Homo sapiens_hsa005610.71000221
96TGF-beta signaling pathway_Homo sapiens_hsa043500.70041034
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.69947224
98Vitamin digestion and absorption_Homo sapiens_hsa049770.69825077
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.69460322
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.69374915
101p53 signaling pathway_Homo sapiens_hsa041150.68717240
102Ovarian steroidogenesis_Homo sapiens_hsa049130.68412106
103Pathways in cancer_Homo sapiens_hsa052000.68168725
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67809678
105AMPK signaling pathway_Homo sapiens_hsa041520.67728051
106Endocytosis_Homo sapiens_hsa041440.66474727
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66270057
108Galactose metabolism_Homo sapiens_hsa000520.66195063
109Melanogenesis_Homo sapiens_hsa049160.65447928
110Glucagon signaling pathway_Homo sapiens_hsa049220.64078219
111Pancreatic cancer_Homo sapiens_hsa052120.63230846
112Pancreatic secretion_Homo sapiens_hsa049720.62259899
113Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.61908227
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.60674539
115Acute myeloid leukemia_Homo sapiens_hsa052210.60082723
116Glioma_Homo sapiens_hsa052140.59846959
117Primary bile acid biosynthesis_Homo sapiens_hsa001200.59521851
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59489672
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.58979075
120Retinol metabolism_Homo sapiens_hsa008300.58702452
121Prolactin signaling pathway_Homo sapiens_hsa049170.56913075
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55673299
123Apoptosis_Homo sapiens_hsa042100.54421951
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54005014
125Hepatitis C_Homo sapiens_hsa051600.53132941
126beta-Alanine metabolism_Homo sapiens_hsa004100.52763952
127Pyruvate metabolism_Homo sapiens_hsa006200.52242046
128Dorso-ventral axis formation_Homo sapiens_hsa043200.52214703
129Rap1 signaling pathway_Homo sapiens_hsa040150.52100968
130Thyroid hormone synthesis_Homo sapiens_hsa049180.51907674
131Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51210475
132Propanoate metabolism_Homo sapiens_hsa006400.49990409
133Arginine and proline metabolism_Homo sapiens_hsa003300.48290857
134Viral myocarditis_Homo sapiens_hsa054160.47902631
135Prostate cancer_Homo sapiens_hsa052150.46392529
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44797688

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