CDC20P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.99970871
2mitotic sister chromatid segregation (GO:0000070)5.97196711
3sister chromatid segregation (GO:0000819)5.59464007
4mitotic metaphase plate congression (GO:0007080)5.56834702
5mitotic chromosome condensation (GO:0007076)5.33386081
6CENP-A containing nucleosome assembly (GO:0034080)5.12896367
7chromatin remodeling at centromere (GO:0031055)5.04009900
8kinetochore organization (GO:0051383)4.95155966
9metaphase plate congression (GO:0051310)4.89557365
10protein localization to kinetochore (GO:0034501)4.83066995
11protein localization to chromosome, centromeric region (GO:0071459)4.69110688
12establishment of integrated proviral latency (GO:0075713)4.53186181
13spindle checkpoint (GO:0031577)4.48440627
14histone exchange (GO:0043486)4.37615844
15negative regulation of chromosome segregation (GO:0051985)4.34884964
16mitotic spindle checkpoint (GO:0071174)4.33588013
17DNA ligation (GO:0006266)4.32370540
18negative regulation of mitotic sister chromatid segregation (GO:0033048)4.30918955
19negative regulation of mitotic sister chromatid separation (GO:2000816)4.30918955
20negative regulation of sister chromatid segregation (GO:0033046)4.30918955
21negative regulation of mitotic metaphase/anaphase transition (GO:0045841)4.30918955
22negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)4.30918955
23proteasome assembly (GO:0043248)4.29889560
24establishment of chromosome localization (GO:0051303)4.28590161
25DNA topological change (GO:0006265)4.25955441
26regulation of chromosome segregation (GO:0051983)4.23697834
27kinetochore assembly (GO:0051382)4.23490623
28DNA strand elongation involved in DNA replication (GO:0006271)4.16993783
29mitotic spindle assembly checkpoint (GO:0007094)4.16119882
30regulation of mitotic spindle organization (GO:0060236)4.11190659
31DNA replication-independent nucleosome organization (GO:0034724)4.11134867
32DNA replication-independent nucleosome assembly (GO:0006336)4.11134867
33spindle assembly checkpoint (GO:0071173)4.09611625
34mitotic nuclear envelope disassembly (GO:0007077)4.04362211
35DNA unwinding involved in DNA replication (GO:0006268)4.02252003
36regulation of spindle organization (GO:0090224)4.01570105
37DNA strand elongation (GO:0022616)4.01313017
38regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.99194166
39regulation of mitotic metaphase/anaphase transition (GO:0030071)3.99194166
40attachment of spindle microtubules to kinetochore (GO:0008608)3.97793670
41telomere maintenance via semi-conservative replication (GO:0032201)3.91764132
42regulation of mitotic sister chromatid separation (GO:0010965)3.85549685
43regulation of mitotic sister chromatid segregation (GO:0033047)3.85549685
44regulation of sister chromatid segregation (GO:0033045)3.85549685
45anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.83850869
46nuclear pore complex assembly (GO:0051292)3.81827303
47membrane disassembly (GO:0030397)3.77188120
48nuclear envelope disassembly (GO:0051081)3.77188120
49regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.76245387
50ribosome assembly (GO:0042255)3.71462761
51regulation of centriole replication (GO:0046599)3.65986593
52chromosome segregation (GO:0007059)3.64412159
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.59541535
54positive regulation of chromosome segregation (GO:0051984)3.56079591
55regulation of centrosome cycle (GO:0046605)3.54118473
56positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.54043550
57negative regulation of mitosis (GO:0045839)3.49447875
58DNA double-strand break processing (GO:0000729)3.45805823
59chromosome condensation (GO:0030261)3.42149719
60IMP biosynthetic process (GO:0006188)3.39384129
61mitotic recombination (GO:0006312)3.38345817
62DNA replication checkpoint (GO:0000076)3.38140880
63negative regulation of ligase activity (GO:0051352)3.35934951
64negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.35934951
65nuclear pore organization (GO:0006999)3.35408157
66protein localization to chromosome (GO:0034502)3.34643960
67microtubule depolymerization (GO:0007019)3.34485711
68ventricular cardiac muscle cell development (GO:0055015)3.33605821
69establishment of viral latency (GO:0019043)3.33426461
70telomere maintenance via recombination (GO:0000722)3.29978294
71DNA replication initiation (GO:0006270)3.28858892
72purine nucleobase biosynthetic process (GO:0009113)3.27825633
73DNA replication-dependent nucleosome organization (GO:0034723)3.27555829
74DNA replication-dependent nucleosome assembly (GO:0006335)3.27555829
75mitotic sister chromatid cohesion (GO:0007064)3.27099022
76regulation of double-strand break repair via homologous recombination (GO:0010569)3.24658855
77ATP-dependent chromatin remodeling (GO:0043044)3.23966942
78protein complex localization (GO:0031503)3.17417988
79mitotic spindle organization (GO:0007052)3.16230730
80positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.15193313
81nucleobase biosynthetic process (GO:0046112)3.14228580
82negative regulation of nuclear division (GO:0051784)3.10956231
83deoxyribonucleotide biosynthetic process (GO:0009263)3.10815979
84chromatin assembly or disassembly (GO:0006333)3.08108459
85mitotic cell cycle (GO:0000278)3.08007927
86meiotic chromosome segregation (GO:0045132)3.07299009
87negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)3.06781499
88DNA packaging (GO:0006323)3.05474953
89regulation of ubiquitin-protein transferase activity (GO:0051438)3.05292893
90positive regulation of ligase activity (GO:0051351)3.01804106
91cellular protein complex localization (GO:0034629)2.98718422
92regulation of centrosome duplication (GO:0010824)2.97226154
93negative regulation of cell division (GO:0051782)2.96963691
94synapsis (GO:0007129)2.95046839
95regulation of ligase activity (GO:0051340)2.94368447
96regulation of sister chromatid cohesion (GO:0007063)2.93282084
97IMP metabolic process (GO:0046040)2.92573716
98telomere maintenance via telomere lengthening (GO:0010833)2.91817267
99nuclear envelope organization (GO:0006998)2.91421460
100G1/S transition of mitotic cell cycle (GO:0000082)2.89012308

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.68928704
2FOXM1_23109430_ChIP-Seq_U2OS_Human6.83668900
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.93899849
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.72082004
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.35229549
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.57510304
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.17656710
8AR_21909140_ChIP-Seq_LNCAP_Human3.12863346
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.06930191
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.03089514
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.94183692
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.85502921
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.81502923
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.74815438
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.70736423
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.70541013
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.62356630
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54318244
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.48109563
20ETS1_20019798_ChIP-Seq_JURKAT_Human2.44453267
21KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.42217339
22SALL1_21062744_ChIP-ChIP_HESCs_Human2.38195237
23E2F1_21310950_ChIP-Seq_MCF-7_Human2.37568955
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.35184257
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32692788
26DCP1A_22483619_ChIP-Seq_HELA_Human2.25381645
27MYCN_18555785_ChIP-Seq_MESCs_Mouse2.10705101
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08794995
29ELK1_19687146_ChIP-ChIP_HELA_Human2.07105305
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95749273
31YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.95601331
32FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.91898722
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.90757938
34FOXP3_21729870_ChIP-Seq_TREG_Human1.89212834
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88880923
36VDR_23849224_ChIP-Seq_CD4+_Human1.82102822
37XRN2_22483619_ChIP-Seq_HELA_Human1.80894253
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.80573536
39TTF2_22483619_ChIP-Seq_HELA_Human1.69897996
40GABP_19822575_ChIP-Seq_HepG2_Human1.69493544
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.66143757
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.65796926
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64181283
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.60743169
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.52635349
46EWS_26573619_Chip-Seq_HEK293_Human1.51690166
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49792936
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42629885
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38399501
50MYC_18940864_ChIP-ChIP_HL60_Human1.35839227
51POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33175089
52CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.33134770
53TP63_19390658_ChIP-ChIP_HaCaT_Human1.33103296
54E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.32884135
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.27233337
56CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.26956547
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.26637973
58NANOG_16153702_ChIP-ChIP_HESCs_Human1.23813197
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22739852
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.20344560
61TAF15_26573619_Chip-Seq_HEK293_Human1.18463082
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.15859482
63KDM5A_27292631_Chip-Seq_BREAST_Human1.12062694
64YY1_21170310_ChIP-Seq_MESCs_Mouse1.10029177
65ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06337584
66SOX17_20123909_ChIP-Seq_XEN_Mouse1.02364566
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.02074244
68CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99557226
69ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97424053
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.95541811
71POU5F1_16153702_ChIP-ChIP_HESCs_Human0.91683519
72NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.91667310
73IGF1R_20145208_ChIP-Seq_DFB_Human0.90849668
74KLF4_18555785_ChIP-Seq_MESCs_Mouse0.89145996
75CIITA_25753668_ChIP-Seq_RAJI_Human0.87170291
76SOX2_16153702_ChIP-ChIP_HESCs_Human0.87138855
77CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.86441951
78ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.85810447
79SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.83538093
80SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.82574179
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.82041978
82NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81937397
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.79969645
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.79900771
85TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.79005081
86HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.77796794
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.77161720
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.73444193
89FUS_26573619_Chip-Seq_HEK293_Human0.73405930
90TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.73148668
91CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.71868122
92TFEB_21752829_ChIP-Seq_HELA_Human0.71645307
93NOTCH1_21737748_ChIP-Seq_TLL_Human0.70313252
94SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.70067595
95NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.69942604
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.69518982
97BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.69242774
98SOX9_26525672_Chip-Seq_HEART_Mouse0.69043585
99NANOG_21062744_ChIP-ChIP_HESCs_Human0.66621611
100STAT3_1855785_ChIP-Seq_MESCs_Mouse0.66302767

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.08641538
2MP0003693_abnormal_embryo_hatching5.01855047
3MP0003111_abnormal_nucleus_morphology4.85913194
4MP0004957_abnormal_blastocyst_morpholog4.72742388
5MP0003077_abnormal_cell_cycle3.82046054
6MP0008058_abnormal_DNA_repair3.79286760
7MP0008057_abnormal_DNA_replication3.22448963
8MP0008932_abnormal_embryonic_tissue3.11312067
9MP0002102_abnormal_ear_morphology2.47944741
10MP0003718_maternal_effect2.46416932
11MP0008007_abnormal_cellular_replicative2.32694638
12MP0003941_abnormal_skin_development2.17867969
13MP0001730_embryonic_growth_arrest2.09232527
14MP0003890_abnormal_embryonic-extraembry1.99839700
15MP0009697_abnormal_copulation1.94878967
16MP0000350_abnormal_cell_proliferation1.79152405
17MP0003786_premature_aging1.72278177
18MP0010030_abnormal_orbit_morphology1.67637657
19MP0001672_abnormal_embryogenesis/_devel1.67393226
20MP0005380_embryogenesis_phenotype1.67393226
21MP0001697_abnormal_embryo_size1.66821426
22MP0010307_abnormal_tumor_latency1.60704856
23MP0002085_abnormal_embryonic_tissue1.58598550
24MP0003937_abnormal_limbs/digits/tail_de1.56517678
25MP0002080_prenatal_lethality1.52126560
26MP0001293_anophthalmia1.48341537
27MP0001529_abnormal_vocalization1.45619474
28MP0006035_abnormal_mitochondrial_morpho1.44456306
29MP0006292_abnormal_olfactory_placode1.43339347
30MP0000372_irregular_coat_pigmentation1.41696293
31MP0010352_gastrointestinal_tract_polyps1.40892990
32MP0002084_abnormal_developmental_patter1.36936863
33MP0009672_abnormal_birth_weight1.32102737
34MP0003984_embryonic_growth_retardation1.29449087
35MP0002796_impaired_skin_barrier1.27790323
36MP0002210_abnormal_sex_determination1.25273371
37MP0002088_abnormal_embryonic_growth/wei1.24225187
38MP0003806_abnormal_nucleotide_metabolis1.22809152
39MP0008877_abnormal_DNA_methylation1.21466364
40MP0001929_abnormal_gametogenesis1.20316450
41MP0010234_abnormal_vibrissa_follicle1.18893902
42MP0000313_abnormal_cell_death1.17488053
43MP0002111_abnormal_tail_morphology1.15975337
44MP0001188_hyperpigmentation1.15894514
45MP0003119_abnormal_digestive_system1.14289972
46MP0006036_abnormal_mitochondrial_physio1.12956638
47MP0003123_paternal_imprinting1.12850855
48MP0002234_abnormal_pharynx_morphology1.10357329
49MP0002938_white_spotting1.09452037
50MP0002736_abnormal_nociception_after1.08418829
51MP0002086_abnormal_extraembryonic_tissu1.07377762
52MP0000579_abnormal_nail_morphology1.05655147
53MP0001661_extended_life_span1.05083952
54MP0009703_decreased_birth_body1.03261678
55MP0004197_abnormal_fetal_growth/weight/1.02228542
56MP0001145_abnormal_male_reproductive0.97340628
57MP0003755_abnormal_palate_morphology0.97162166
58MP0005501_abnormal_skin_physiology0.96158005
59MP0002233_abnormal_nose_morphology0.95946080
60MP0000358_abnormal_cell_content/0.94497146
61MP0000647_abnormal_sebaceous_gland0.92257934
62MP0002160_abnormal_reproductive_system0.90964580
63MP0000653_abnormal_sex_gland0.90784295
64MP0002697_abnormal_eye_size0.89800848
65MP0000537_abnormal_urethra_morphology0.85368384
66MP0008789_abnormal_olfactory_epithelium0.85298697
67MP0003861_abnormal_nervous_system0.82827058
68MP0000049_abnormal_middle_ear0.81937922
69MP0001286_abnormal_eye_development0.81000596
70MP0003698_abnormal_male_reproductive0.79432929
71MP0001177_atelectasis0.78776933
72MP0004147_increased_porphyrin_level0.78296485
73MP0006054_spinal_hemorrhage0.78062138
74MP0003935_abnormal_craniofacial_develop0.77654990
75MP0004233_abnormal_muscle_weight0.76731420
76MP0000490_abnormal_crypts_of0.76727600
77MP0005395_other_phenotype0.76308956
78MP0000428_abnormal_craniofacial_morphol0.74791202
79MP0002161_abnormal_fertility/fecundity0.74362493
80MP0002060_abnormal_skin_morphology0.74219907
81MP0003567_abnormal_fetal_cardiomyocyte0.73912802
82MP0003385_abnormal_body_wall0.73910407
83MP0003137_abnormal_impulse_conducting0.73587130
84MP0002396_abnormal_hematopoietic_system0.70880359
85MP0003950_abnormal_plasma_membrane0.70399024
86MP0004185_abnormal_adipocyte_glucose0.69796830
87MP0002019_abnormal_tumor_incidence0.69011058
88MP0002177_abnormal_outer_ear0.67760344
89MP0001727_abnormal_embryo_implantation0.67401396
90MP0003699_abnormal_female_reproductive0.64756114
91MP0000432_abnormal_head_morphology0.62095305
92MP0003221_abnormal_cardiomyocyte_apopto0.61781138
93MP0002095_abnormal_skin_pigmentation0.61465474
94MP0000462_abnormal_digestive_system0.60428391
95MP0002877_abnormal_melanocyte_morpholog0.59641378
96MP0001119_abnormal_female_reproductive0.59549757
97MP0002269_muscular_atrophy0.59340075
98MP0002114_abnormal_axial_skeleton0.58755872
99MP0002751_abnormal_autonomic_nervous0.58467216
100MP0002092_abnormal_eye_morphology0.57414582

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.98642434
2Increased serum pyruvate (HP:0003542)3.72454026
3Abnormal lung lobation (HP:0002101)3.66493950
4Abnormality of glycolysis (HP:0004366)3.62757940
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.55833745
6Birth length less than 3rd percentile (HP:0003561)3.28017811
7Increased nuchal translucency (HP:0010880)3.27796586
8Chromsome breakage (HP:0040012)3.24355002
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.12319516
10Abnormality of the preputium (HP:0100587)3.06369227
11Meckel diverticulum (HP:0002245)3.04607699
12Progressive external ophthalmoplegia (HP:0000590)3.01373128
13Abnormality of chromosome stability (HP:0003220)2.95832024
14Small intestinal stenosis (HP:0012848)2.93638237
15Duodenal stenosis (HP:0100867)2.93638237
16Abnormality of the ileum (HP:0001549)2.84649963
17Colon cancer (HP:0003003)2.80204660
18Aplasia/Hypoplasia of the sacrum (HP:0008517)2.75011826
19Embryonal renal neoplasm (HP:0011794)2.67102230
20Nephroblastoma (Wilms tumor) (HP:0002667)2.57021265
21Abnormality of the labia minora (HP:0012880)2.56007989
22Increased hepatocellular lipid droplets (HP:0006565)2.51479289
23Prominent metopic ridge (HP:0005487)2.50858283
24Abnormality of the duodenum (HP:0002246)2.48499143
25Cerebral hypomyelination (HP:0006808)2.45821316
26Cortical dysplasia (HP:0002539)2.45216138
27Multiple enchondromatosis (HP:0005701)2.40415911
28Microvesicular hepatic steatosis (HP:0001414)2.39306758
29Hypoplastic pelvis (HP:0008839)2.35045603
30Acute encephalopathy (HP:0006846)2.35000843
31Facial cleft (HP:0002006)2.32413637
32Myelodysplasia (HP:0002863)2.30128772
33Sloping forehead (HP:0000340)2.28588191
34Glioma (HP:0009733)2.27217432
35Acute necrotizing encephalopathy (HP:0006965)2.26819858
36Ependymoma (HP:0002888)2.25598449
37Abnormal umbilical cord blood vessels (HP:0011403)2.19922160
38Single umbilical artery (HP:0001195)2.19922160
39Abnormality of the fetal cardiovascular system (HP:0010948)2.19922160
40Abnormality of the umbilical cord (HP:0010881)2.16985064
41Urethral obstruction (HP:0000796)2.15077635
42Myelomeningocele (HP:0002475)2.14813146
43Lipid accumulation in hepatocytes (HP:0006561)2.14209971
44Medulloblastoma (HP:0002885)2.13368587
45Horseshoe kidney (HP:0000085)2.11002670
46Abnormal mitochondria in muscle tissue (HP:0008316)2.10184327
47Abnormality of the metopic suture (HP:0005556)2.10160862
48Increased serum lactate (HP:0002151)2.08621377
49Hypoplasia of the pons (HP:0012110)2.08241472
50Abnormality of the carotid arteries (HP:0005344)2.07535027
51Astrocytoma (HP:0009592)2.06867402
52Abnormality of the astrocytes (HP:0100707)2.06867402
53Increased CSF lactate (HP:0002490)2.04163360
54Pancreatic islet-cell hyperplasia (HP:0004510)2.01871152
55Postnatal microcephaly (HP:0005484)2.00058956
56Squamous cell carcinoma (HP:0002860)1.98628596
57Proximal placement of thumb (HP:0009623)1.97526711
58Rhabdomyosarcoma (HP:0002859)1.97250292
59Clubbing of toes (HP:0100760)1.96707247
60Small hand (HP:0200055)1.96570900
61Absent radius (HP:0003974)1.95751896
62Aplasia/Hypoplasia of the patella (HP:0006498)1.90995215
63Abnormality of the pons (HP:0007361)1.90775546
64Bifid tongue (HP:0010297)1.90428014
65Abnormality of alanine metabolism (HP:0010916)1.88955332
66Hyperalaninemia (HP:0003348)1.88955332
67Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.88955332
68Progressive muscle weakness (HP:0003323)1.88387806
69Aplasia involving forearm bones (HP:0009822)1.88000453
70Absent forearm bone (HP:0003953)1.88000453
71Patellar aplasia (HP:0006443)1.87294406
72Abnormality of the anterior horn cell (HP:0006802)1.87108964
73Degeneration of anterior horn cells (HP:0002398)1.87108964
74CNS hypomyelination (HP:0003429)1.86271137
75Selective tooth agenesis (HP:0001592)1.85801853
76Breast hypoplasia (HP:0003187)1.84529911
77Rough bone trabeculation (HP:0100670)1.83556090
78Neoplasm of the colon (HP:0100273)1.81468895
79Choanal atresia (HP:0000453)1.81069547
80Mitochondrial inheritance (HP:0001427)1.80352453
81Deviation of the thumb (HP:0009603)1.75555629
82Premature ovarian failure (HP:0008209)1.75186938
83Progressive macrocephaly (HP:0004481)1.75084398
84Abnormalities of placenta or umbilical cord (HP:0001194)1.74520422
85Dandy-Walker malformation (HP:0001305)1.71685202
86Preaxial hand polydactyly (HP:0001177)1.71396074
87Abnormality of chromosome segregation (HP:0002916)1.68260967
88Progressive inability to walk (HP:0002505)1.68132162
89Arteriovenous malformation (HP:0100026)1.67564611
90Posterior subcapsular cataract (HP:0007787)1.67520534
91Lactic acidosis (HP:0003128)1.67475201
92Anal atresia (HP:0002023)1.67201076
93Cafe-au-lait spot (HP:0000957)1.66717208
94Hypoplasia of the capital femoral epiphysis (HP:0003090)1.66639132
95Abnormality of abdominal situs (HP:0011620)1.66354972
96Abdominal situs inversus (HP:0003363)1.66354972
97Carpal bone hypoplasia (HP:0001498)1.66339823
98Cerebral edema (HP:0002181)1.66276667
99Neoplasm of the adrenal cortex (HP:0100641)1.65649718
100Short middle phalanx of the 5th finger (HP:0004220)1.63431898

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB17.04097464
2NEK16.09527099
3PLK43.32562378
4TTK3.28988186
5NEK22.99312264
6VRK22.91889542
7WEE12.87994368
8CDC72.78294800
9EIF2AK12.44488031
10TSSK62.41329953
11PLK32.35045541
12EIF2AK32.24842409
13SRPK12.13045006
14MKNK22.09732297
15PBK1.99540507
16PLK11.84855909
17MST41.79247207
18VRK11.75678437
19ZAK1.71759605
20MKNK11.71285661
21TRIM281.69946299
22TNIK1.62677975
23BRAF1.46706518
24AURKB1.27656554
25BRSK11.26919844
26NUAK11.25661126
27CHEK21.23758546
28STK101.16544339
29BRSK21.13594823
30CCNB11.12866097
31MAP3K101.08853370
32STK161.07234684
33ATR1.05202034
34EPHA41.03876356
35TAF11.01748909
36AURKA1.01519900
37EIF2AK20.98325285
38MAP3K80.96451983
39STK30.88637689
40NME20.85480458
41CHEK10.84227281
42MAP4K20.83015454
43ERBB30.82137370
44SMG10.79259497
45WNK30.74205375
46CDK70.73335006
47NTRK30.68611058
48DYRK30.68077836
49BCR0.67951832
50ATM0.66972397
51RPS6KA40.66298202
52MAPK130.64786550
53NME10.64449474
54PDK20.63419386
55PNCK0.62725834
56SCYL20.59989421
57PAK40.59763017
58ALK0.58248389
59LATS20.57305244
60STK40.56590608
61CDK10.55526390
62MST1R0.53826918
63CLK10.50070361
64TLK10.49532629
65CDK20.46649739
66CSNK1E0.42892276
67PLK20.41289067
68SIK30.41101799
69MARK30.40713957
70CSNK2A10.40422254
71MAPKAPK50.37085931
72UHMK10.36512954
73PAK10.35720963
74MINK10.35306139
75CSNK2A20.35095642
76NEK60.35087943
77RPS6KB20.34934404
78CDK30.34801434
79CDK80.34319359
80PRKCI0.33137129
81CDK90.32594574
82EEF2K0.32212656
83DMPK0.32194852
84CDK180.31942481
85PASK0.31851568
86IRAK20.31106434
87CSNK1G30.30233222
88IRAK30.30001858
89AKT20.29202931
90BRD40.28785847
91CDK40.28640162
92ROCK20.28276615
93CDK140.27363453
94CDK150.26058648
95CDK60.25276881
96MELK0.25211773
97CDK11A0.25076311
98CSNK1G10.24749517
99ILK0.22229171
100YES10.19415467

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.06378792
2DNA replication_Homo sapiens_hsa030304.06184157
3Mismatch repair_Homo sapiens_hsa034303.58207650
4Non-homologous end-joining_Homo sapiens_hsa034503.20261323
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.18417312
6Cell cycle_Homo sapiens_hsa041102.98883344
7Homologous recombination_Homo sapiens_hsa034402.96198517
8RNA transport_Homo sapiens_hsa030132.59062912
9Spliceosome_Homo sapiens_hsa030402.53747468
10Base excision repair_Homo sapiens_hsa034102.46910982
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.44649466
12RNA polymerase_Homo sapiens_hsa030202.42660047
13Nucleotide excision repair_Homo sapiens_hsa034202.35107860
14Fanconi anemia pathway_Homo sapiens_hsa034602.26578255
15Basal transcription factors_Homo sapiens_hsa030222.24338820
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.12379684
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.07598548
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.99768873
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.86565630
20One carbon pool by folate_Homo sapiens_hsa006701.86524949
21Pyrimidine metabolism_Homo sapiens_hsa002401.86429789
22Steroid biosynthesis_Homo sapiens_hsa001001.84546690
23RNA degradation_Homo sapiens_hsa030181.81168111
24Pyruvate metabolism_Homo sapiens_hsa006201.56115129
25mRNA surveillance pathway_Homo sapiens_hsa030151.54839201
26Oocyte meiosis_Homo sapiens_hsa041141.47067685
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.46913988
28p53 signaling pathway_Homo sapiens_hsa041151.45401692
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.44462678
30Protein export_Homo sapiens_hsa030601.34534924
31Ribosome_Homo sapiens_hsa030101.30757672
32Propanoate metabolism_Homo sapiens_hsa006401.29686844
33Parkinsons disease_Homo sapiens_hsa050121.28114710
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.27996446
35Purine metabolism_Homo sapiens_hsa002301.26725396
36Vitamin B6 metabolism_Homo sapiens_hsa007501.26405320
37Huntingtons disease_Homo sapiens_hsa050161.14318521
38Oxidative phosphorylation_Homo sapiens_hsa001901.09513463
39Biosynthesis of amino acids_Homo sapiens_hsa012301.08658573
40Selenocompound metabolism_Homo sapiens_hsa004501.08318841
41Fatty acid elongation_Homo sapiens_hsa000621.06570585
42Carbon metabolism_Homo sapiens_hsa012001.01376907
43Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00850243
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.99273297
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97223192
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.96486329
47Sulfur relay system_Homo sapiens_hsa041220.92906048
48Glutathione metabolism_Homo sapiens_hsa004800.91528546
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.85264252
50TGF-beta signaling pathway_Homo sapiens_hsa043500.79558805
51Sulfur metabolism_Homo sapiens_hsa009200.75416506
52Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71702737
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71667756
54Alzheimers disease_Homo sapiens_hsa050100.66456130
55Hippo signaling pathway_Homo sapiens_hsa043900.64219401
56Epstein-Barr virus infection_Homo sapiens_hsa051690.63642215
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61171541
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58297281
59Fatty acid metabolism_Homo sapiens_hsa012120.54442938
60Pentose phosphate pathway_Homo sapiens_hsa000300.50498487
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50224012
62Metabolic pathways_Homo sapiens_hsa011000.48933881
63Central carbon metabolism in cancer_Homo sapiens_hsa052300.48637992
64Basal cell carcinoma_Homo sapiens_hsa052170.47569273
65Wnt signaling pathway_Homo sapiens_hsa043100.46465014
66Hedgehog signaling pathway_Homo sapiens_hsa043400.43953436
67Folate biosynthesis_Homo sapiens_hsa007900.43119679
68Phototransduction_Homo sapiens_hsa047440.42270243
69N-Glycan biosynthesis_Homo sapiens_hsa005100.42246952
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41532134
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41473585
72Viral carcinogenesis_Homo sapiens_hsa052030.37956236
73Butanoate metabolism_Homo sapiens_hsa006500.37404787
74MicroRNAs in cancer_Homo sapiens_hsa052060.31868114
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.31811758
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31548747
77Colorectal cancer_Homo sapiens_hsa052100.30976206
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27922916
79Lysine degradation_Homo sapiens_hsa003100.26569961
80HTLV-I infection_Homo sapiens_hsa051660.25893648
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24262627
82Adherens junction_Homo sapiens_hsa045200.23228634
83Taste transduction_Homo sapiens_hsa047420.22053949
84Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.20914769
85Vitamin digestion and absorption_Homo sapiens_hsa049770.20051849
86Alcoholism_Homo sapiens_hsa050340.19192694
87Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.19123352
88Arginine and proline metabolism_Homo sapiens_hsa003300.18088997
89Tight junction_Homo sapiens_hsa045300.17724413
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.17193698
91Thyroid cancer_Homo sapiens_hsa052160.12813579
92Systemic lupus erythematosus_Homo sapiens_hsa053220.12809094
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.11462759
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.11317324
95Prostate cancer_Homo sapiens_hsa052150.09938383
96Small cell lung cancer_Homo sapiens_hsa052220.08122905
97Melanoma_Homo sapiens_hsa052180.07459934
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.02864098
99Fatty acid degradation_Homo sapiens_hsa000710.02794199
100Tyrosine metabolism_Homo sapiens_hsa003500.00477009

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »