CD93

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lymph vessel development (GO:0001945)7.41177683
2endothelium development (GO:0003158)6.24497785
3vascular endothelial growth factor signaling pathway (GO:0038084)6.20824920
4positive regulation of vasculogenesis (GO:2001214)5.81496031
5angiogenesis involved in wound healing (GO:0060055)5.59128570
6blood vessel maturation (GO:0001955)5.24306908
7retina vasculature morphogenesis in camera-type eye (GO:0061299)4.99073408
8regulation of vasculogenesis (GO:2001212)4.78796202
9cellular response to vascular endothelial growth factor stimulus (GO:0035924)4.74315587
10sprouting angiogenesis (GO:0002040)4.72204498
11definitive hemopoiesis (GO:0060216)4.51102050
12morphogenesis of an endothelium (GO:0003159)4.49066853
13endothelial tube morphogenesis (GO:0061154)4.49066853
14substrate-dependent cell migration (GO:0006929)4.38170788
15antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.20057882
16regulation of endothelial cell differentiation (GO:0045601)4.08883537
17patterning of blood vessels (GO:0001569)4.01277590
18cellular extravasation (GO:0045123)3.98549030
19detection of molecule of bacterial origin (GO:0032490)3.97293597
20response to peptidoglycan (GO:0032494)3.92895477
21basement membrane organization (GO:0071711)3.89752708
22establishment of endothelial barrier (GO:0061028)3.87748361
23negative regulation of nitric-oxide synthase activity (GO:0051001)3.86682028
24vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.81350798
25regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.80097335
26detection of other organism (GO:0098543)3.80043511
27negative regulation of interleukin-12 production (GO:0032695)3.79823741
28lymphangiogenesis (GO:0001946)3.76468420
29modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.74995256
30positive regulation by organism of defense response of other organism involved in symbiotic interact3.74995256
31modulation by symbiont of host immune response (GO:0052553)3.74995256
32positive regulation by symbiont of host defense response (GO:0052509)3.74995256
33modulation by symbiont of host defense response (GO:0052031)3.74995256
34modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.74995256
35surfactant homeostasis (GO:0043129)3.68029729
36regulation of interferon-beta biosynthetic process (GO:0045357)3.65794808
37negative regulation of nitric oxide biosynthetic process (GO:0045019)3.63325790
38negative regulation of cell killing (GO:0031342)3.62730210
39negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.62730210
40glomerular filtration (GO:0003094)3.62728970
41ovulation from ovarian follicle (GO:0001542)3.44575701
42negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.42475488
43detection of external biotic stimulus (GO:0098581)3.42403037
44positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.40269616
45Rap protein signal transduction (GO:0032486)3.40253836
46negative regulation of phagocytosis (GO:0050765)3.39764538
47endothelial cell morphogenesis (GO:0001886)3.39418354
48wound healing, spreading of epidermal cells (GO:0035313)3.37909816
49positive regulation of B cell differentiation (GO:0045579)3.34999614
50megakaryocyte development (GO:0035855)3.29216809
51detection of bacterium (GO:0016045)3.26425758
52transcytosis (GO:0045056)3.23650446
53endothelial cell differentiation (GO:0045446)3.22768395
54negative regulation of erythrocyte differentiation (GO:0045647)3.22503326
55regulation of B cell receptor signaling pathway (GO:0050855)3.21898016
56positive regulation of smooth muscle cell migration (GO:0014911)3.18270266
57histamine secretion (GO:0001821)3.16661179
58renal filtration (GO:0097205)3.16383718
59Notch signaling involved in heart development (GO:0061314)3.13672008
60regulation of dendritic cell antigen processing and presentation (GO:0002604)3.12534989
61macrophage activation involved in immune response (GO:0002281)3.11689237
62antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.11408478
63antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.11408478
64response to muramyl dipeptide (GO:0032495)3.10850591
65positive regulation of interferon-alpha production (GO:0032727)3.10708782
66neutrophil activation involved in immune response (GO:0002283)3.09173136
67detection of biotic stimulus (GO:0009595)3.08899252
68regulation of gamma-delta T cell activation (GO:0046643)3.02920294
69microglial cell activation (GO:0001774)3.01643984
70* macrophage activation (GO:0042116)3.01579105
71neutrophil mediated immunity (GO:0002446)3.00327256
72phagocytosis, recognition (GO:0006910)3.00000613
73positive regulation of gamma-delta T cell activation (GO:0046645)2.96581804
74positive regulation of endothelial cell differentiation (GO:0045603)2.96295919
75blood vessel endothelial cell migration (GO:0043534)2.93089438
76membrane raft organization (GO:0031579)2.91579758
77mRNA transcription from RNA polymerase II promoter (GO:0042789)2.91450934
78negative regulation of platelet activation (GO:0010544)2.91424587
79regulation of interferon-alpha production (GO:0032647)2.90782676
80vasculogenesis (GO:0001570)2.90262043
81regulation of metalloenzyme activity (GO:0048552)2.90187870
82cell adhesion mediated by integrin (GO:0033627)2.88929537
83venous blood vessel morphogenesis (GO:0048845)2.88243250
84pinocytosis (GO:0006907)2.88028138
85trabecula morphogenesis (GO:0061383)2.87894262
86positive regulation of Rap GTPase activity (GO:0032854)2.87182213
87positive regulation of receptor recycling (GO:0001921)2.85157416
88negative regulation of blood vessel endothelial cell migration (GO:0043537)2.85023727
89coronary vasculature morphogenesis (GO:0060977)2.84889916
90leukocyte migration involved in inflammatory response (GO:0002523)2.84620571
91ventricular trabecula myocardium morphogenesis (GO:0003222)2.84160428
92cell migration involved in sprouting angiogenesis (GO:0002042)2.84086022
93positive regulation of phosphatidylinositol 3-kinase activity (GO:0043552)2.80831537
94neutrophil activation (GO:0042119)2.80339915
95germinal center formation (GO:0002467)2.79492746
96negative regulation of endothelial cell migration (GO:0010596)2.79148939
97response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.78793334
98response to host (GO:0075136)2.78793334
99response to host defenses (GO:0052200)2.78793334
100protein localization to endosome (GO:0036010)2.77667769
101endothelial cell development (GO:0001885)2.76704935
102regulation of cellular extravasation (GO:0002691)2.76569624
103positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.76098451
104regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.75859703
105B cell receptor signaling pathway (GO:0050853)2.74440624
106regulation of mast cell degranulation (GO:0043304)2.73912469
107positive regulation of cell junction assembly (GO:1901890)2.73817356
108positive regulation of focal adhesion assembly (GO:0051894)2.73817356
109regulation of sarcomere organization (GO:0060297)2.73339076
110regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)2.70375158
111positive regulation of lipid kinase activity (GO:0090218)2.69937774
112regulation of T-helper 2 cell differentiation (GO:0045628)2.69439211
113negative regulation of endothelial cell apoptotic process (GO:2000352)2.69229639
114regulation of platelet activation (GO:0010543)2.68141459
115production of molecular mediator involved in inflammatory response (GO:0002532)2.66200033
116embryonic hemopoiesis (GO:0035162)2.66052356
117heart trabecula formation (GO:0060347)2.63856961
118granulocyte activation (GO:0036230)2.62679244
119positive regulation of mast cell activation (GO:0033005)2.62512277
120regulation of tolerance induction (GO:0002643)2.62499323
121chemical homeostasis within a tissue (GO:0048875)2.62138866
122positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.61834945
123lipopolysaccharide-mediated signaling pathway (GO:0031663)2.59931102
124positive regulation of odontogenesis (GO:0042482)2.59508353
125heart trabecula morphogenesis (GO:0061384)2.58915897
126peptidyl-tyrosine autophosphorylation (GO:0038083)2.58502213
127histamine transport (GO:0051608)2.58125241
128response to fluid shear stress (GO:0034405)2.58050309
129response to host immune response (GO:0052572)2.57982523
130response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.57982523
131negative regulation of stress fiber assembly (GO:0051497)2.57919001
132positive regulation of keratinocyte differentiation (GO:0045618)2.57519080
133regulation of leukocyte degranulation (GO:0043300)2.56754963
134regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.56545366
135antigen processing and presentation of endogenous antigen (GO:0019883)2.55457548
136neutrophil chemotaxis (GO:0030593)2.55012758
137regulation of T cell tolerance induction (GO:0002664)2.55005327
138regulation of gamma-delta T cell differentiation (GO:0045586)2.54046720
139regulation of myeloid leukocyte mediated immunity (GO:0002886)2.53886352
140monocyte chemotaxis (GO:0002548)2.53621847
141regulation of mast cell activation involved in immune response (GO:0033006)2.53203530
142myeloid cell activation involved in immune response (GO:0002275)2.52100378
143positive regulation of tolerance induction (GO:0002645)2.51519920
144regulation of macrophage cytokine production (GO:0010935)2.50349398
145leukocyte aggregation (GO:0070486)2.49378845
146regulation of mast cell activation (GO:0033003)2.48914397
147regulation of blood vessel endothelial cell migration (GO:0043535)2.48667675
148neutrophil migration (GO:1990266)2.48184698
149negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.41388815

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.67894714
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.84742727
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.23537750
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.03000578
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.02821910
6GATA2_21666600_ChIP-Seq_HMVEC_Human3.98760108
7SCL_19346495_ChIP-Seq_HPC-7_Human3.66084861
8GATA1_22025678_ChIP-Seq_K562_Human3.62668173
9E2F7_22180533_ChIP-Seq_HELA_Human3.29167546
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.15242965
11IRF8_21731497_ChIP-ChIP_J774_Mouse3.14718287
12EGR1_19374776_ChIP-ChIP_THP-1_Human3.12131159
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.94365978
14* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.77590319
15* IRF8_27001747_Chip-Seq_BMDM_Mouse2.74949521
16TRIM28_21343339_ChIP-Seq_HEK293_Human2.68085803
17* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.64563967
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.61736149
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.52257024
20TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.49163249
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.44438358
22RUNX_20019798_ChIP-Seq_JUKART_Human2.43894718
23STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.23973416
24IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.14875142
25Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.12993712
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.79366513
27SPI1_23127762_ChIP-Seq_K562_Human1.77609053
28RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.75540579
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.74866116
30* ELK3_25401928_ChIP-Seq_HUVEC_Human1.74347855
31FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.68293105
32* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.66482996
33MYB_26560356_Chip-Seq_TH2_Human1.63459965
34MAF_26560356_Chip-Seq_TH1_Human1.63048960
35* SPI1_23547873_ChIP-Seq_NB4_Human1.62196995
36* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61861208
37PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.57168582
38* VDR_24787735_ChIP-Seq_THP-1_Human1.55583461
39THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.53597797
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.52384824
41SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.52192813
42* VDR_24763502_ChIP-Seq_THP-1_Human1.51898913
43STAT4_19710469_ChIP-ChIP_TH1__Mouse1.48295436
44HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47420542
45TCF7_22412390_ChIP-Seq_EML_Mouse1.46337946
46KDM2B_26808549_Chip-Seq_SUP-B15_Human1.46243351
47GATA1_19941827_ChIP-Seq_MEL_Mouse1.45366673
48MYB_26560356_Chip-Seq_TH1_Human1.42442287
49CLOCK_20551151_ChIP-Seq_293T_Human1.42100474
50WT1_19549856_ChIP-ChIP_CCG9911_Human1.37814540
51PU_27001747_Chip-Seq_BMDM_Mouse1.36747801
52SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.35551691
53SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.35551691
54GATA1_19941826_ChIP-Seq_K562_Human1.35004792
55CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.34079444
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.33364136
57KDM2B_26808549_Chip-Seq_DND41_Human1.31545890
58HIF1A_21447827_ChIP-Seq_MCF-7_Human1.29708255
59VDR_21846776_ChIP-Seq_THP-1_Human1.29683263
60TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.29402196
61STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.29125569
62RUNX1_22412390_ChIP-Seq_EML_Mouse1.28829032
63* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.25548154
64MYC_22102868_ChIP-Seq_BL_Human1.25538967
65CJUN_26792858_Chip-Seq_BT549_Human1.25318097
66UTX_26944678_Chip-Seq_JUKART_Human1.24896503
67FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.23904819
68SALL4_18804426_ChIP-ChIP_XEN_Mouse1.23470203
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.21672584
70PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20929655
71CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.20587370
72TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18687610
73ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.17944082
74RARG_19884340_ChIP-ChIP_MEFs_Mouse1.17664359
75CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15758825
76RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.15011921
77CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14931535
78ESR2_21235772_ChIP-Seq_MCF-7_Human1.13630330
79EP300_21415370_ChIP-Seq_HL-1_Mouse1.13483387
80LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.12282976
81GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.11925624
82PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11434754
83BRD4_25478319_ChIP-Seq_HGPS_Human1.11355353
84EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.09508607
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09438406
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.09396123
87CDX2_20551321_ChIP-Seq_CACO-2_Human1.07068682
88KDM2B_26808549_Chip-Seq_JURKAT_Human1.06388105
89CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.04057389
90SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.03218849
91KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02665085
92SOX2_20726797_ChIP-Seq_SW620_Human0.99115535
93VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99101563
94STAT6_21828071_ChIP-Seq_BEAS2B_Human0.98494661
95FOXM1_23109430_ChIP-Seq_U2OS_Human0.98109219
96* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97870036
97E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.97469706
98* GATA2_19941826_ChIP-Seq_K562_Human0.97443027
99TP63_17297297_ChIP-ChIP_HaCaT_Human0.97247559
100TBX20_22080862_ChIP-Seq_HEART_Mouse0.96543652
101TBX20_22328084_ChIP-Seq_HEART_Mouse0.96543652
102KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.96155702
103GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95500880
104* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.95204554
105GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94963869
106FOXO3_23340844_ChIP-Seq_DLD1_Human0.94942085
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94786149
108GATA1_19941827_ChIP-Seq_MEL86_Mouse0.94663561
109* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93969951
110GATA3_27048872_Chip-Seq_THYMUS_Human0.93657608
111FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.93332963
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.93190930
113KDM2B_26808549_Chip-Seq_K562_Human0.92579710
114ESR1_21235772_ChIP-Seq_MCF-7_Human0.91588692
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90837833
116LXR_22292898_ChIP-Seq_THP-1_Human0.89039021
117CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88562751
118SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88261088
119NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86958423
120* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.85323018
121LXR_22158963_ChIP-Seq_LIVER_Mouse0.84875905
122GATA1_22383799_ChIP-Seq_G1ME_Mouse0.81122051
123* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78992855
124BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78544851
125SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.78521580

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010368_abnormal_lymphatic_system5.28262757
2MP0001879_abnormal_lymphatic_vessel4.78769988
3MP0003828_pulmonary_edema3.63438821
4MP0005167_abnormal_blood-brain_barrier3.54789301
5MP0003724_increased_susceptibility_to3.48574574
6MP0009278_abnormal_bone_marrow3.18713003
7MP0004272_abnormal_basement_membrane3.04325947
8MP0003191_abnormal_cellular_cholesterol2.75730240
9MP0004147_increased_porphyrin_level2.60315719
10MP0006054_spinal_hemorrhage2.55932237
11MP0003950_abnormal_plasma_membrane2.35894808
12MP0005397_hematopoietic_system_phenotyp2.24951968
13MP0001545_abnormal_hematopoietic_system2.24951968
14MP0003705_abnormal_hypodermis_morpholog2.15050789
15MP0003300_gastrointestinal_ulcer2.06377751
16MP0000767_abnormal_smooth_muscle2.03224966
17MP0009379_abnormal_foot_pigmentation2.00544481
18MP0002396_abnormal_hematopoietic_system1.92805682
19MP0003303_peritoneal_inflammation1.83335291
20MP0009785_altered_susceptibility_to1.78841576
21MP0006082_CNS_inflammation1.77217461
22MP0004808_abnormal_hematopoietic_stem1.76893375
23MP0005171_absent_coat_pigmentation1.75013159
24MP0002332_abnormal_exercise_endurance1.73469232
25MP0001835_abnormal_antigen_presentation1.64780125
26MP0001853_heart_inflammation1.63354349
27MP0000343_altered_response_to1.61874818
28MP0009780_abnormal_chondrocyte_physiolo1.55479556
29MP0000249_abnormal_blood_vessel1.54757249
30MP0010352_gastrointestinal_tract_polyps1.53652404
31MP0002166_altered_tumor_susceptibility1.52695597
32MP0008004_abnormal_stomach_pH1.51391658
33MP0008260_abnormal_autophagy1.48342295
34MP0003091_abnormal_cell_migration1.44913782
35MP0005409_darkened_coat_color1.44741582
36* MP0002419_abnormal_innate_immunity1.43607685
37MP0000465_gastrointestinal_hemorrhage1.42755709
38MP0003279_aneurysm1.38218260
39MP0003943_abnormal_hepatobiliary_system1.35448644
40MP0005451_abnormal_body_composition1.35268249
41MP0005058_abnormal_lysosome_morphology1.34601226
42MP0002933_joint_inflammation1.32846189
43MP0004883_abnormal_blood_vessel1.32342177
44MP0002998_abnormal_bone_remodeling1.32030578
45MP0004084_abnormal_cardiac_muscle1.30634345
46MP0003566_abnormal_cell_adhesion1.28944549
47MP0005025_abnormal_response_to1.26949429
48MP0002148_abnormal_hypersensitivity_rea1.26783419
49MP0003436_decreased_susceptibility_to1.26175249
50* MP0002452_abnormal_antigen_presenting1.24495352
51MP0006138_congestive_heart_failure1.23878439
52MP0004782_abnormal_surfactant_physiolog1.22513685
53MP0004947_skin_inflammation1.20776179
54MP0003448_altered_tumor_morphology1.20480499
55MP0001915_intracranial_hemorrhage1.20038302
56MP0005165_increased_susceptibility_to1.19577444
57MP0003172_abnormal_lysosome_physiology1.17046898
58MP0005464_abnormal_platelet_physiology1.16311576
59MP0001188_hyperpigmentation1.15330998
60* MP0002420_abnormal_adaptive_immunity1.14224915
61MP0005166_decreased_susceptibility_to1.14031623
62* MP0001819_abnormal_immune_cell1.13804586
63MP0002925_abnormal_cardiovascular_devel1.13546477
64MP0001800_abnormal_humoral_immune1.13299260
65MP0010155_abnormal_intestine_physiology1.13183773
66MP0003045_fibrosis1.12922678
67MP0005164_abnormal_response_to1.12229311
68MP0005671_abnormal_response_to1.12159347
69MP0003690_abnormal_glial_cell1.11930620
70MP0001533_abnormal_skeleton_physiology1.11808407
71MP0005000_abnormal_immune_tolerance1.09535031
72MP0002128_abnormal_blood_circulation1.09196072
73MP0005387_immune_system_phenotype1.08914490
74MP0001790_abnormal_immune_system1.08914490
75MP0005084_abnormal_gallbladder_morpholo1.08870493
76MP0002723_abnormal_immune_serum1.07469889
77MP0002405_respiratory_system_inflammati1.06746965
78MP0001851_eye_inflammation1.05345136
79MP0000015_abnormal_ear_pigmentation1.05236779
80MP0001873_stomach_inflammation1.04151397
81MP0010630_abnormal_cardiac_muscle1.03256169
82MP0001614_abnormal_blood_vessel1.02832683
83MP0005360_urolithiasis1.02280220
84MP0000858_altered_metastatic_potential1.00181327
85MP0002006_tumorigenesis0.98739735
86MP0009764_decreased_sensitivity_to0.97996298
87MP0002398_abnormal_bone_marrow0.97552852
88MP0001958_emphysema0.94225410
89MP0003763_abnormal_thymus_physiology0.92646501
90MP0005595_abnormal_vascular_smooth0.92594884
91MP0002877_abnormal_melanocyte_morpholog0.92216976
92MP0005385_cardiovascular_system_phenoty0.91971858
93MP0001544_abnormal_cardiovascular_syste0.91971858
94MP0004484_altered_response_of0.90468335
95MP0002127_abnormal_cardiovascular_syste0.89378514
96MP0004510_myositis0.89013266
97MP0008995_early_reproductive_senescence0.87916609
98MP0000716_abnormal_immune_system0.87347792
99MP0003567_abnormal_fetal_cardiomyocyte0.87325067
100MP0008469_abnormal_protein_level0.86334538
101MP0000689_abnormal_spleen_morphology0.86043694
102MP0010234_abnormal_vibrissa_follicle0.86009201
103MP0000372_irregular_coat_pigmentation0.85599509
104MP0002429_abnormal_blood_cell0.83625669
105MP0002138_abnormal_hepatobiliary_system0.82267039
106MP0005388_respiratory_system_phenotype0.79655337
107MP0002133_abnormal_respiratory_system0.79655337
108MP0000685_abnormal_immune_system0.79326653
109MP0002295_abnormal_pulmonary_circulatio0.78509611
110MP0002722_abnormal_immune_system0.77915281
111MP0005390_skeleton_phenotype0.77483802
112MP0001845_abnormal_inflammatory_respons0.76767005
113MP0002086_abnormal_extraembryonic_tissu0.75414855
114MP0004130_abnormal_muscle_cell0.74276579
115MP0004036_abnormal_muscle_relaxation0.73619955
116MP0009333_abnormal_splenocyte_physiolog0.73107512
117MP0003075_altered_response_to0.71799972
118MP0001849_ear_inflammation0.71796873
119MP0001784_abnormal_fluid_regulation0.71496418
120MP0000013_abnormal_adipose_tissue0.70468737

Predicted human phenotypes

RankGene SetZ-score
1Spontaneous hematomas (HP:0007420)5.41389678
2Hematochezia (HP:0002573)5.15304661
3Esophageal varix (HP:0002040)3.92718048
4Reduced subcutaneous adipose tissue (HP:0003758)3.92438425
5Polycythemia (HP:0001901)3.58474236
6Recurrent abscess formation (HP:0002722)3.58417045
7Porencephaly (HP:0002132)3.48597415
8Mucosal telangiectasiae (HP:0100579)3.26102999
9Cellulitis (HP:0100658)3.25910152
10Nonimmune hydrops fetalis (HP:0001790)3.25659033
11Amyloidosis (HP:0011034)3.24725998
12Adactyly (HP:0009776)3.19451596
13Absent hand (HP:0004050)3.13778313
14Asymmetry of the thorax (HP:0001555)3.12677686
15Myositis (HP:0100614)3.10999550
16Stomatitis (HP:0010280)3.10994412
17Hemiplegia (HP:0002301)3.05685176
18Cerebral aneurysm (HP:0004944)2.98388219
19Colitis (HP:0002583)2.98309170
20Eczematoid dermatitis (HP:0000976)2.98139047
21Conjunctival telangiectasia (HP:0000524)2.96459080
22Cerebral hemorrhage (HP:0001342)2.90848898
23Cutis marmorata (HP:0000965)2.84607348
24Abnormality of the vasculature of the conjunctiva (HP:0008054)2.80880651
25Prolonged bleeding time (HP:0003010)2.78442064
26Growth hormone excess (HP:0000845)2.77730256
27Facial diplegia (HP:0001349)2.77722765
28Difficulty running (HP:0009046)2.75642027
29Portal hypertension (HP:0001409)2.71797913
30Gingivitis (HP:0000230)2.70046779
31Muscle fiber splitting (HP:0003555)2.69898246
32Skull defect (HP:0001362)2.69717530
33Recurrent bacterial skin infections (HP:0005406)2.68088326
34Elevated erythrocyte sedimentation rate (HP:0003565)2.67291757
35Abnormality of the nasal mucosa (HP:0000433)2.63944521
36Obstructive lung disease (HP:0006536)2.58720894
37Chronic obstructive pulmonary disease (HP:0006510)2.58720894
38Orchitis (HP:0100796)2.56289396
39Keratoconjunctivitis (HP:0001096)2.55460585
40Abnormality of the hepatic vasculature (HP:0006707)2.53814271
41Thyroiditis (HP:0100646)2.53374815
42Papilledema (HP:0001085)2.52624733
43Chest pain (HP:0100749)2.51256184
44Myocardial infarction (HP:0001658)2.51101418
45Osteomyelitis (HP:0002754)2.49439264
46Abnormality of macrophages (HP:0004311)2.49170786
47Gastrointestinal infarctions (HP:0005244)2.48708543
48Recurrent skin infections (HP:0001581)2.48314227
49Vacuolated lymphocytes (HP:0001922)2.42173529
50Acute myeloid leukemia (HP:0004808)2.41245320
51Recurrent viral infections (HP:0004429)2.41196861
52J-shaped sella turcica (HP:0002680)2.39134838
53Increased IgE level (HP:0003212)2.39131742
54Abnormality of glycosphingolipid metabolism (HP:0004343)2.37851578
55Abnormality of glycolipid metabolism (HP:0010969)2.37851578
56Abnormality of liposaccharide metabolism (HP:0010968)2.37851578
57Arterial tortuosity (HP:0005116)2.37802342
58Lymphangioma (HP:0100764)2.36949989
59Bone cyst (HP:0012062)2.36204835
60Inflammation of the large intestine (HP:0002037)2.32928591
61Pulmonary hypertension (HP:0002092)2.32142336
62Congenital, generalized hypertrichosis (HP:0004540)2.29718170
63Peritonitis (HP:0002586)2.28442244
64Hemorrhage of the eye (HP:0011885)2.27025428
65Joint hemorrhage (HP:0005261)2.26664438
66Capillary hemangiomas (HP:0005306)2.26290371
67High pitched voice (HP:0001620)2.25629239
68Vasculitis (HP:0002633)2.21792158
69Distal lower limb muscle weakness (HP:0009053)2.21739022
70Pulmonary embolism (HP:0002204)2.20495880
71Thrombocytosis (HP:0001894)2.18721825
72Menorrhagia (HP:0000132)2.18690014
73Episodic fever (HP:0001954)2.17855563
74Lymphedema (HP:0001004)2.17701466
75Gastrointestinal inflammation (HP:0004386)2.16973233
76Subacute progressive viral hepatitis (HP:0006572)2.16237779
77Pulmonary infiltrates (HP:0002113)2.14901757
78Arterial thrombosis (HP:0004420)2.14096862
79Mediastinal lymphadenopathy (HP:0100721)2.13917982
80Chronic otitis media (HP:0000389)2.12011659
81Increased cerebral lipofuscin (HP:0011813)2.11839121
82Protrusio acetabuli (HP:0003179)2.11812943
83Agammaglobulinemia (HP:0004432)2.11672674
84Interstitial pulmonary disease (HP:0006530)2.11432384
85Wrist flexion contracture (HP:0001239)2.11415216
86Recurrent fungal infections (HP:0002841)2.10409521
87Vascular tortuosity (HP:0004948)2.10287215
88Dysostosis multiplex (HP:0000943)2.09785005
89Asymmetric septal hypertrophy (HP:0001670)2.09651587
90Aortic aneurysm (HP:0004942)2.08446428
91Meningitis (HP:0001287)2.08219729
92Basal ganglia calcification (HP:0002135)2.07963215
93Tetraparesis (HP:0002273)2.06375735
94Stroke (HP:0001297)2.05338967
95Gingival bleeding (HP:0000225)2.05116293
96Systemic lupus erythematosus (HP:0002725)2.03654082
97Hyporeflexia of lower limbs (HP:0002600)2.03243316
98Abnormal platelet volume (HP:0011876)2.03207644
99Increased connective tissue (HP:0009025)2.03003042
100Hemoptysis (HP:0002105)2.02447387
101Abnormality of skeletal muscle fiber size (HP:0012084)2.02287565
102Xerostomia (HP:0000217)2.00370330
103Chronic mucocutaneous candidiasis (HP:0002728)2.00239465
104Recurrent cutaneous fungal infections (HP:0011370)2.00239465
105Thrombophlebitis (HP:0004418)1.98999127
106Abnormality of the lumbar spine (HP:0100712)1.97998795
107Increased variability in muscle fiber diameter (HP:0003557)1.95872530
108Short 4th metacarpal (HP:0010044)1.95630597
109Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.95630597
110Glucose intolerance (HP:0000833)1.95618476
111Aneurysm (HP:0002617)1.95577950
112Abnormality of the peritoneum (HP:0002585)1.95243593
113Autoimmune thrombocytopenia (HP:0001973)1.94945000
114Vertigo (HP:0002321)1.93920732
115Epistaxis (HP:0000421)1.93744968
116Aplasia cutis congenita (HP:0001057)1.93656251
117Retrobulbar optic neuritis (HP:0100654)1.93551292
118Optic neuritis (HP:0100653)1.93551292
119Urticaria (HP:0001025)1.93263064
120Leukocytosis (HP:0001974)1.92506773
121Increased neuronal autofluorescent lipopigment (HP:0002074)1.91795293
122Encephalitis (HP:0002383)1.90838366
123Cerebral ischemia (HP:0002637)1.90195262
124Pulmonary artery stenosis (HP:0004415)1.90100098
125Difficulty climbing stairs (HP:0003551)1.88972980
126Hepatosplenomegaly (HP:0001433)1.88486455
127Abnormal delayed hypersensitivity skin test (HP:0002963)1.87178187
128Hemangiomatosis (HP:0007461)1.86719124
129Keratoconjunctivitis sicca (HP:0001097)1.86202096
130Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.86168138
131Microcytic anemia (HP:0001935)1.85985715
132Recurrent gram-negative bacterial infections (HP:0005420)1.85348930
133Teleangiectasia of the skin (HP:0100585)1.85277541
134Increased mean platelet volume (HP:0011877)1.84820151
135Hypercholesterolemia (HP:0003124)1.83064105
136Large hands (HP:0001176)1.82888755
137Enlarged penis (HP:0000040)1.82887817
138Petechiae (HP:0000967)1.81976859
139Visceral angiomatosis (HP:0100761)1.81810238
140Prostate neoplasm (HP:0100787)1.80700145
141Joint contractures involving the joints of the feet (HP:0100492)1.79150283
142Flexion contracture of toe (HP:0005830)1.79150283
143Cutaneous melanoma (HP:0012056)1.78815357
144Thick nail (HP:0001805)1.77909535
145Abnormal platelet function (HP:0011869)1.77757067
146Impaired platelet aggregation (HP:0003540)1.77757067
147Sepsis (HP:0100806)1.76936031
148Chondrocalcinosis (HP:0000934)1.76861276

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE17.84740849
2KDR5.72172227
3TGFBR23.23892672
4TGFBR13.02112511
5BLK2.41729236
6MAP3K142.28608332
7MAP2K32.09820322
8KIT1.99362868
9TEC1.90421661
10CLK11.89474383
11FGFR31.85855643
12PRPF4B1.75911787
13RIPK11.69918050
14FRK1.69078839
15FER1.60946016
16STK101.55304693
17INSRR1.52195410
18PTK2B1.50514968
19ERN11.49025855
20MAP3K131.43648849
21EPHB11.41748449
22MAPK71.37722267
23DMPK1.37681714
24TYK21.36374644
25MAPK121.34571843
26IRAK31.33274595
27PTK61.28285956
28TBK11.27083451
29FGR1.26086568
30MAP4K11.19079469
31LRRK21.17700719
32TSSK61.16976674
33CSK1.16835164
34FES1.16172466
35EPHB21.15403727
36MAP3K11.12029837
37FGFR21.11661376
38MAP3K31.09375824
39NEK91.06335639
40ITK1.05313997
41NUAK11.04415744
42BTK1.01249262
43MAP3K111.00161476
44IRAK40.96970099
45CAMK1D0.96472030
46NLK0.96441789
47MARK30.96115036
48KSR20.95123317
49JAK30.94063526
50TRPM70.89765459
51PIK3CG0.89299520
52IKBKE0.87923121
53MAP3K100.87454693
54MOS0.87046717
55IRAK10.86309223
56MAP3K60.85516197
57MATK0.84498659
58MARK20.83500253
59PAK40.82666179
60BMPR1B0.81134526
61PIM10.81106325
62STK30.80314527
63YES10.79909307
64HCK0.79422077
65PRKG20.77975907
66PKN20.77033825
67ZAK0.76977533
68JAK10.73876800
69ZAP700.72921157
70GRK10.72292863
71PDPK10.69766823
72TTN0.69259201
73TAOK30.67455484
74STK40.65498121
75TNK20.64614484
76CAMK1G0.64382934
77FLT30.63870797
78CDK90.63794305
79ABL10.63400339
80LCK0.63335004
81TXK0.62299233
82LYN0.62270665
83CSF1R0.62089542
84CDK60.61841046
85MAP3K70.61796767
86FGFR40.61603797
87CHUK0.61557017
88SGK30.60817053
89PIM20.60782057
90MYLK0.60679557
91IKBKB0.59803835
92TAOK10.57868713
93PDK10.57851966
94TRIB30.57116252
95BMPR20.56329484
96MAPK40.55769740
97CDC42BPA0.55509190
98CDK80.55165126
99SYK0.54658423
100IRAK20.52460399
101EGFR0.51318733
102MAP3K20.48283956
103IGF1R0.47287622
104RPS6KA20.46842044
105RET0.46828748
106PRKD20.42969903
107PDK20.42731548
108PDGFRA0.41248489
109RIPK40.41214269
110FYN0.41203421
111STK240.40546552
112JAK20.37973611
113PRKCQ0.36162925
114EPHA30.35479411
115PRKD10.35245869
116SCYL20.34380746
117EIF2AK20.34256344
118RPS6KC10.33941138
119RPS6KL10.33941138
120SIK30.33179188
121PRKAA20.31497060
122CDK40.30877875
123SRC0.29817152
124TAOK20.29476610
125MAP3K80.28912155
126INSR0.28537970
127KSR10.27472853
128PDGFRB0.26725070
129AKT30.25918592
130STK110.25874457
131GRK60.24954909
132SIK20.24314542
133SGK20.24008824
134MST40.23978230
135PRKCD0.23243223

Predicted pathways (KEGG)

RankGene SetZ-score
1Leukocyte transendothelial migration_Homo sapiens_hsa046702.21072235
2Leishmaniasis_Homo sapiens_hsa051402.12352234
3B cell receptor signaling pathway_Homo sapiens_hsa046622.07889915
4Malaria_Homo sapiens_hsa051442.01313423
5Viral myocarditis_Homo sapiens_hsa054161.98310566
6NF-kappa B signaling pathway_Homo sapiens_hsa040641.97503017
7Hematopoietic cell lineage_Homo sapiens_hsa046401.92253167
8Osteoclast differentiation_Homo sapiens_hsa043801.91791991
9Toxoplasmosis_Homo sapiens_hsa051451.89579187
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.84149954
11Adherens junction_Homo sapiens_hsa045201.82025649
12Focal adhesion_Homo sapiens_hsa045101.81738847
13Small cell lung cancer_Homo sapiens_hsa052221.80570570
14Measles_Homo sapiens_hsa051621.79218605
15Platelet activation_Homo sapiens_hsa046111.78473233
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.77358656
17Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.76490895
18Shigellosis_Homo sapiens_hsa051311.63745169
19Staphylococcus aureus infection_Homo sapiens_hsa051501.62450656
20Pertussis_Homo sapiens_hsa051331.61021878
21ECM-receptor interaction_Homo sapiens_hsa045121.56027161
22African trypanosomiasis_Homo sapiens_hsa051431.55287564
23Influenza A_Homo sapiens_hsa051641.44002998
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.43221126
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.37761424
26Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.31933132
27TNF signaling pathway_Homo sapiens_hsa046681.31668610
28Transcriptional misregulation in cancer_Homo sapiens_hsa052021.30881932
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.30663785
30Graft-versus-host disease_Homo sapiens_hsa053321.30026820
31Salmonella infection_Homo sapiens_hsa051321.26541727
32Legionellosis_Homo sapiens_hsa051341.25928726
33Herpes simplex infection_Homo sapiens_hsa051681.23710754
34Apoptosis_Homo sapiens_hsa042101.22321714
35Hepatitis B_Homo sapiens_hsa051611.22115008
36Allograft rejection_Homo sapiens_hsa053301.21863266
37Chronic myeloid leukemia_Homo sapiens_hsa052201.21459797
38Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.17263183
39Rap1 signaling pathway_Homo sapiens_hsa040151.16513144
40HIF-1 signaling pathway_Homo sapiens_hsa040661.15829358
41Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.15532775
42Antigen processing and presentation_Homo sapiens_hsa046121.14803819
43Tuberculosis_Homo sapiens_hsa051521.13843846
44Dorso-ventral axis formation_Homo sapiens_hsa043201.13384964
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.12986524
46Amoebiasis_Homo sapiens_hsa051461.10668160
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10228572
48PI3K-Akt signaling pathway_Homo sapiens_hsa041511.10133950
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.09801921
50Notch signaling pathway_Homo sapiens_hsa043301.09726567
51Intestinal immune network for IgA production_Homo sapiens_hsa046721.09582848
52Jak-STAT signaling pathway_Homo sapiens_hsa046301.08181231
53Autoimmune thyroid disease_Homo sapiens_hsa053201.08115846
54Proteoglycans in cancer_Homo sapiens_hsa052051.07056541
55T cell receptor signaling pathway_Homo sapiens_hsa046601.04734800
56Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04363275
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.04269801
58Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03656690
59Primary immunodeficiency_Homo sapiens_hsa053401.02793192
60MicroRNAs in cancer_Homo sapiens_hsa052061.02523539
61Chemokine signaling pathway_Homo sapiens_hsa040621.01608111
62Regulation of actin cytoskeleton_Homo sapiens_hsa048101.00025620
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.98611843
64Pancreatic cancer_Homo sapiens_hsa052120.98296924
65Other glycan degradation_Homo sapiens_hsa005110.96961308
66Hepatitis C_Homo sapiens_hsa051600.96461989
67HTLV-I infection_Homo sapiens_hsa051660.95076616
68Acute myeloid leukemia_Homo sapiens_hsa052210.94872801
69Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.93899619
70Dilated cardiomyopathy_Homo sapiens_hsa054140.93123889
71Pathways in cancer_Homo sapiens_hsa052000.90925511
72Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90043911
73GnRH signaling pathway_Homo sapiens_hsa049120.88056059
74Phagosome_Homo sapiens_hsa041450.87396278
75Prostate cancer_Homo sapiens_hsa052150.86365954
76Lysosome_Homo sapiens_hsa041420.86159561
77Complement and coagulation cascades_Homo sapiens_hsa046100.84239669
78Non-small cell lung cancer_Homo sapiens_hsa052230.83692002
79VEGF signaling pathway_Homo sapiens_hsa043700.82532980
80Prolactin signaling pathway_Homo sapiens_hsa049170.82038046
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81530649
82Renal cell carcinoma_Homo sapiens_hsa052110.79877934
83Type I diabetes mellitus_Homo sapiens_hsa049400.78711934
84FoxO signaling pathway_Homo sapiens_hsa040680.78259639
85Bladder cancer_Homo sapiens_hsa052190.77477270
86Prion diseases_Homo sapiens_hsa050200.77409316
87Insulin resistance_Homo sapiens_hsa049310.77303004
88Rheumatoid arthritis_Homo sapiens_hsa053230.76292720
89Ras signaling pathway_Homo sapiens_hsa040140.75567100
90DNA replication_Homo sapiens_hsa030300.75068874
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.72243434
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.71794434
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71231828
94Renin-angiotensin system_Homo sapiens_hsa046140.70933472
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68800303
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.66147721
97Choline metabolism in cancer_Homo sapiens_hsa052310.63449434
98Endocytosis_Homo sapiens_hsa041440.62998356
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62539319
100Estrogen signaling pathway_Homo sapiens_hsa049150.61833590
101Viral carcinogenesis_Homo sapiens_hsa052030.61825236
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61026017
103TGF-beta signaling pathway_Homo sapiens_hsa043500.60825445
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59767383
105Base excision repair_Homo sapiens_hsa034100.58781219
106Epstein-Barr virus infection_Homo sapiens_hsa051690.58404383
107Endometrial cancer_Homo sapiens_hsa052130.57767156
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56804427
109Thyroid cancer_Homo sapiens_hsa052160.56147217
110mTOR signaling pathway_Homo sapiens_hsa041500.55145697
111Caffeine metabolism_Homo sapiens_hsa002320.53048377
112Phospholipase D signaling pathway_Homo sapiens_hsa040720.52023045
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.51671024
114Glioma_Homo sapiens_hsa052140.51120033
115Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.50766138
116Inositol phosphate metabolism_Homo sapiens_hsa005620.49175797
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46671682
118MAPK signaling pathway_Homo sapiens_hsa040100.45286322
119Colorectal cancer_Homo sapiens_hsa052100.44116466
120Asthma_Homo sapiens_hsa053100.42593489
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41192090
122Sphingolipid metabolism_Homo sapiens_hsa006000.40333492

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