CD24P4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.29532121
2ATP synthesis coupled proton transport (GO:0015986)7.22673867
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.22673867
4sequestering of actin monomers (GO:0042989)6.98431948
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.71369878
6viral transcription (GO:0019083)5.61494283
7respiratory electron transport chain (GO:0022904)5.61115513
8chaperone-mediated protein transport (GO:0072321)5.54975469
9translational termination (GO:0006415)5.53389289
10electron transport chain (GO:0022900)5.51018392
11ribosomal small subunit assembly (GO:0000028)5.06627604
12protein neddylation (GO:0045116)5.04816972
13cotranslational protein targeting to membrane (GO:0006613)4.87219823
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.87108365
15neuron fate determination (GO:0048664)4.86363595
16protein targeting to ER (GO:0045047)4.76119783
17establishment of protein localization to mitochondrial membrane (GO:0090151)4.70165170
18protein complex biogenesis (GO:0070271)4.65994158
19mitochondrial respiratory chain complex I assembly (GO:0032981)4.57543725
20NADH dehydrogenase complex assembly (GO:0010257)4.57543725
21mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.57543725
22establishment of protein localization to endoplasmic reticulum (GO:0072599)4.55819305
23respiratory chain complex IV assembly (GO:0008535)4.53566847
24maturation of SSU-rRNA (GO:0030490)4.43904782
25translational elongation (GO:0006414)4.43175692
26ribosomal small subunit biogenesis (GO:0042274)4.39758900
27protein localization to endoplasmic reticulum (GO:0070972)4.39320359
28termination of RNA polymerase III transcription (GO:0006386)4.33114536
29transcription elongation from RNA polymerase III promoter (GO:0006385)4.33114536
30mitochondrial respiratory chain complex assembly (GO:0033108)4.32754213
31nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.24498249
32cellular protein complex disassembly (GO:0043624)4.23845549
33viral life cycle (GO:0019058)4.20473494
34cytochrome complex assembly (GO:0017004)4.17816866
35translational initiation (GO:0006413)4.07238357
36ATP biosynthetic process (GO:0006754)4.02429757
37hydrogen ion transmembrane transport (GO:1902600)3.98772840
38nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.95095156
39spermatid nucleus differentiation (GO:0007289)3.95031401
40exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.94351450
41establishment of integrated proviral latency (GO:0075713)3.92725973
42behavioral response to nicotine (GO:0035095)3.91352307
43protein complex disassembly (GO:0043241)3.75058127
44ribosomal large subunit biogenesis (GO:0042273)3.63347303
45spliceosomal snRNP assembly (GO:0000387)3.59186876
46macromolecular complex disassembly (GO:0032984)3.57544005
47purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.56401957
48CENP-A containing nucleosome assembly (GO:0034080)3.53999329
49chromatin remodeling at centromere (GO:0031055)3.52900408
50proton transport (GO:0015992)3.51883290
51epithelial cilium movement (GO:0003351)3.51382630
52purine nucleoside triphosphate biosynthetic process (GO:0009145)3.50275610
53hydrogen transport (GO:0006818)3.46016176
54pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.45447135
55regulation of mitochondrial translation (GO:0070129)3.42058045
56spliceosomal complex assembly (GO:0000245)3.40740465
57translation (GO:0006412)3.34905521
58inner mitochondrial membrane organization (GO:0007007)3.31750854
59establishment of viral latency (GO:0019043)3.30398460
60DNA replication checkpoint (GO:0000076)3.28056493
61ribonucleoside triphosphate biosynthetic process (GO:0009201)3.24643367
62nuclear-transcribed mRNA catabolic process (GO:0000956)3.23695557
63histone exchange (GO:0043486)3.21420197
64rRNA modification (GO:0000154)3.20756112
65protein targeting to membrane (GO:0006612)3.17131201
66proteasome assembly (GO:0043248)3.11915936
67mRNA catabolic process (GO:0006402)3.05599991
68base-excision repair, AP site formation (GO:0006285)2.99583818
69regulation of mitotic spindle checkpoint (GO:1903504)2.96062815
70regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.96062815
71protein localization to kinetochore (GO:0034501)2.92529214
72neuron fate specification (GO:0048665)2.91915025
73protein targeting to mitochondrion (GO:0006626)2.88275383
74pyrimidine nucleotide catabolic process (GO:0006244)2.84548811
75protein localization to mitochondrion (GO:0070585)2.84396336
76nucleoside triphosphate biosynthetic process (GO:0009142)2.84202896
77purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.82235075
78purine nucleoside monophosphate biosynthetic process (GO:0009127)2.82235075
79kinetochore assembly (GO:0051382)2.81443895
80purine nucleobase biosynthetic process (GO:0009113)2.79381859
81RNA catabolic process (GO:0006401)2.79201817
82cellular component biogenesis (GO:0044085)2.78418171
83establishment of protein localization to mitochondrion (GO:0072655)2.78148757
84negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.75489640
85regulation of chromatin binding (GO:0035561)2.74364243
86mitotic metaphase plate congression (GO:0007080)2.74057643
87pteridine-containing compound biosynthetic process (GO:0042559)2.72098375
88water-soluble vitamin biosynthetic process (GO:0042364)2.71910001
89histone mRNA metabolic process (GO:0008334)2.71675476
90DNA replication-independent nucleosome assembly (GO:0006336)2.71580926
91DNA replication-independent nucleosome organization (GO:0034724)2.71580926
92regulation of helicase activity (GO:0051095)2.68917754
93kinetochore organization (GO:0051383)2.68559305
94oxidative phosphorylation (GO:0006119)2.67928311
95mitochondrial transport (GO:0006839)2.67169571
96cilium movement (GO:0003341)2.66167757
97platelet dense granule organization (GO:0060155)2.64952375
98otic vesicle formation (GO:0030916)2.62743925
99intracellular protein transmembrane import (GO:0044743)2.61899018
100peptidyl-histidine modification (GO:0018202)2.59392414

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.31598061
2EST1_17652178_ChIP-ChIP_JURKAT_Human4.11374376
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.01590917
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.93237360
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.37545648
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.19029907
7E2F7_22180533_ChIP-Seq_HELA_Human3.04271578
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.95880615
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.89780473
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.69670725
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.65143129
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.64086286
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.63521880
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.58987447
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.53975367
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.53474407
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.46846352
18ELK1_19687146_ChIP-ChIP_HELA_Human2.28627133
19EZH2_22144423_ChIP-Seq_EOC_Human2.21146807
20TTF2_22483619_ChIP-Seq_HELA_Human2.10488181
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.10300905
22MYC_19079543_ChIP-ChIP_MESCs_Mouse2.07621087
23YY1_21170310_ChIP-Seq_MESCs_Mouse2.02344499
24POU5F1_16153702_ChIP-ChIP_HESCs_Human1.90456504
25MYC_18358816_ChIP-ChIP_MESCs_Mouse1.90387091
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.86364103
27MYC_19030024_ChIP-ChIP_MESCs_Mouse1.85764530
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.83620255
29FOXP3_21729870_ChIP-Seq_TREG_Human1.79269871
30SOX2_16153702_ChIP-ChIP_HESCs_Human1.78014632
31XRN2_22483619_ChIP-Seq_HELA_Human1.77934419
32FUS_26573619_Chip-Seq_HEK293_Human1.77541190
33POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.77314618
34MYC_18940864_ChIP-ChIP_HL60_Human1.74558663
35VDR_23849224_ChIP-Seq_CD4+_Human1.72899651
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.68984909
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.58913729
38EWS_26573619_Chip-Seq_HEK293_Human1.58806053
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.52375594
40ZNF274_21170338_ChIP-Seq_K562_Hela1.49832555
41PADI4_21655091_ChIP-ChIP_MCF-7_Human1.47758329
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.46590632
43E2F1_21310950_ChIP-Seq_MCF-7_Human1.44876639
44EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.44386953
45DCP1A_22483619_ChIP-Seq_HELA_Human1.42962110
46NANOG_16153702_ChIP-ChIP_HESCs_Human1.39075270
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.38449481
48SALL1_21062744_ChIP-ChIP_HESCs_Human1.35566183
49DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.34435681
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.34353154
51NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.32705571
52ELK1_22589737_ChIP-Seq_MCF10A_Human1.32475498
53GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.32347923
54SOX2_18555785_ChIP-Seq_MESCs_Mouse1.31433409
55KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.29778344
56KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.29778344
57KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.29778344
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.28115597
59YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25774353
60NELFA_20434984_ChIP-Seq_ESCs_Mouse1.24192067
61P300_19829295_ChIP-Seq_ESCs_Human1.23374653
62FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22550611
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21806459
64ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18450094
65SRF_21415370_ChIP-Seq_HL-1_Mouse1.17303182
66VDR_22108803_ChIP-Seq_LS180_Human1.17195467
67FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17005648
68CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13817910
69EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12353161
70TAF15_26573619_Chip-Seq_HEK293_Human1.11746870
71FLI1_27457419_Chip-Seq_LIVER_Mouse1.06746743
72NANOG_18555785_ChIP-Seq_MESCs_Mouse1.05442358
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03999197
74ERG_20517297_ChIP-Seq_VCAP_Human1.02438049
75GABP_19822575_ChIP-Seq_HepG2_Human1.02285997
76CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.01308726
77POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.00922583
78IGF1R_20145208_ChIP-Seq_DFB_Human0.99236508
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.93056692
80NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.92612007
81MYCN_18555785_ChIP-Seq_MESCs_Mouse0.92112154
82HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91527280
83SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.88883266
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.88811062
85ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82159535
86CBX2_27304074_Chip-Seq_ESCs_Mouse0.81754000
87GATA1_26923725_Chip-Seq_HPCs_Mouse0.80794539
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80739743
89BCAT_22108803_ChIP-Seq_LS180_Human0.79926634
90CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.79396909
91NANOG_19829295_ChIP-Seq_ESCs_Human0.78918298
92SOX2_19829295_ChIP-Seq_ESCs_Human0.78918298
93CBP_20019798_ChIP-Seq_JUKART_Human0.78238481
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.78238481
95AR_21909140_ChIP-Seq_LNCAP_Human0.77215873
96NANOG_20526341_ChIP-Seq_ESCs_Human0.76703253
97TCF4_22108803_ChIP-Seq_LS180_Human0.75313697
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.74025605
99NCOR_22424771_ChIP-Seq_293T_Human0.71382636
100SOX9_26525672_Chip-Seq_HEART_Mouse0.70926475

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.54851758
2MP0000372_irregular_coat_pigmentation3.26877149
3MP0003941_abnormal_skin_development3.05222046
4MP0010386_abnormal_urinary_bladder2.87127226
5MP0002638_abnormal_pupillary_reflex2.78269158
6MP0008058_abnormal_DNA_repair2.51076883
7MP0006292_abnormal_olfactory_placode2.46739042
8MP0003693_abnormal_embryo_hatching2.41068472
9MP0001529_abnormal_vocalization2.40766577
10MP0002653_abnormal_ependyma_morphology2.25160325
11MP0006072_abnormal_retinal_apoptosis2.25116232
12MP0004957_abnormal_blastocyst_morpholog2.16262283
13MP0005645_abnormal_hypothalamus_physiol2.13359848
14MP0001984_abnormal_olfaction2.03996727
15MP0004142_abnormal_muscle_tone2.03765283
16MP0000566_synostosis2.02769320
17MP0003136_yellow_coat_color1.87183606
18MP0004133_heterotaxia1.77132471
19MP0003077_abnormal_cell_cycle1.73013140
20MP0003011_delayed_dark_adaptation1.67717781
21MP0006276_abnormal_autonomic_nervous1.66037217
22MP0002938_white_spotting1.59326484
23MP0008877_abnormal_DNA_methylation1.58714817
24MP0003122_maternal_imprinting1.53865855
25MP0010094_abnormal_chromosome_stability1.52913220
26MP0008789_abnormal_olfactory_epithelium1.52259571
27MP0005253_abnormal_eye_physiology1.51375106
28MP0002796_impaired_skin_barrier1.50383199
29MP0001293_anophthalmia1.48538995
30MP0003111_abnormal_nucleus_morphology1.48453473
31MP0008995_early_reproductive_senescence1.44792283
32MP0001968_abnormal_touch/_nociception1.41897125
33MP0003567_abnormal_fetal_cardiomyocyte1.39422745
34MP0002736_abnormal_nociception_after1.36047014
35MP0008961_abnormal_basal_metabolism1.35878856
36MP0002277_abnormal_respiratory_mucosa1.29883136
37MP0000631_abnormal_neuroendocrine_gland1.27671365
38MP0005377_hearing/vestibular/ear_phenot1.26074877
39MP0003878_abnormal_ear_physiology1.26074877
40MP0005394_taste/olfaction_phenotype1.23358004
41MP0005499_abnormal_olfactory_system1.23358004
42MP0008932_abnormal_embryonic_tissue1.23101674
43MP0002557_abnormal_social/conspecific_i1.19979149
44MP0003938_abnormal_ear_development1.18440758
45MP0003186_abnormal_redox_activity1.17608164
46MP0002734_abnormal_mechanical_nocicepti1.17188544
47MP0000049_abnormal_middle_ear1.15312294
48MP0004742_abnormal_vestibular_system1.14988629
49MP0003121_genomic_imprinting1.14838780
50MP0001485_abnormal_pinna_reflex1.14727664
51MP0010030_abnormal_orbit_morphology1.13053117
52MP0005551_abnormal_eye_electrophysiolog1.12921520
53MP0003119_abnormal_digestive_system1.12294144
54MP0001905_abnormal_dopamine_level1.11751906
55MP0002254_reproductive_system_inflammat1.10592895
56MP0001286_abnormal_eye_development1.09643519
57MP0005410_abnormal_fertilization1.07287907
58MP0002751_abnormal_autonomic_nervous1.03066998
59MP0001486_abnormal_startle_reflex1.02468315
60MP0003880_abnormal_central_pattern1.02036453
61MP0005084_abnormal_gallbladder_morpholo0.99190726
62MP0009046_muscle_twitch0.99032149
63MP0000026_abnormal_inner_ear0.98948366
64MP0006035_abnormal_mitochondrial_morpho0.98543222
65MP0003718_maternal_effect0.97437583
66MP0002272_abnormal_nervous_system0.94502677
67MP0002210_abnormal_sex_determination0.93635810
68MP0003937_abnormal_limbs/digits/tail_de0.91505898
69MP0004270_analgesia0.91104137
70MP0002837_dystrophic_cardiac_calcinosis0.90807811
71MP0001346_abnormal_lacrimal_gland0.90260384
72MP0002697_abnormal_eye_size0.89856594
73MP0000778_abnormal_nervous_system0.88956272
74MP0002234_abnormal_pharynx_morphology0.88607856
75MP0003698_abnormal_male_reproductive0.88245455
76MP0002572_abnormal_emotion/affect_behav0.87216222
77MP0001970_abnormal_pain_threshold0.87116440
78MP0001929_abnormal_gametogenesis0.86594702
79MP0000579_abnormal_nail_morphology0.85459142
80MP0001440_abnormal_grooming_behavior0.85194381
81MP0001188_hyperpigmentation0.84621378
82MP0003890_abnormal_embryonic-extraembry0.84361358
83MP0002752_abnormal_somatic_nervous0.84294907
84MP0009745_abnormal_behavioral_response0.83963852
85MP0002095_abnormal_skin_pigmentation0.83670403
86MP0005195_abnormal_posterior_eye0.83456278
87MP0000538_abnormal_urinary_bladder0.82449798
88MP0000490_abnormal_crypts_of0.81785213
89MP0003315_abnormal_perineum_morphology0.78885173
90MP0001177_atelectasis0.78505436
91MP0001756_abnormal_urination0.78497572
92MP0001764_abnormal_homeostasis0.78346588
93MP0005391_vision/eye_phenotype0.77122155
94MP0003638_abnormal_response/metabolism_0.76774577
95MP0000653_abnormal_sex_gland0.76677245
96MP0005501_abnormal_skin_physiology0.76151237
97MP0001502_abnormal_circadian_rhythm0.75614625
98MP0003195_calcinosis0.74030332
99MP0003787_abnormal_imprinting0.74007600
100MP0001145_abnormal_male_reproductive0.73986019

Predicted human phenotypes

RankGene SetZ-score
1Increased hepatocellular lipid droplets (HP:0006565)5.74047497
2Acute necrotizing encephalopathy (HP:0006965)5.15080830
3Lipid accumulation in hepatocytes (HP:0006561)5.08170364
4Mitochondrial inheritance (HP:0001427)4.92643874
5Renal Fanconi syndrome (HP:0001994)4.72730330
6Acute encephalopathy (HP:0006846)4.44509781
7Abnormal mitochondria in muscle tissue (HP:0008316)4.41602557
8Hepatocellular necrosis (HP:0001404)4.41474876
9Progressive macrocephaly (HP:0004481)4.34244946
10Increased CSF lactate (HP:0002490)4.10423715
11Abnormal number of erythroid precursors (HP:0012131)3.94312302
12Hepatic necrosis (HP:0002605)3.78354994
13Abnormality of cells of the erythroid lineage (HP:0012130)3.77417684
14Colon cancer (HP:0003003)3.73400262
15Respiratory difficulties (HP:0002880)3.71474195
16Abnormality of the labia minora (HP:0012880)3.61231494
17Exertional dyspnea (HP:0002875)3.55694054
18Reticulocytopenia (HP:0001896)3.52701230
19Pendular nystagmus (HP:0012043)3.48266610
20Macrocytic anemia (HP:0001972)3.46271009
21Oral leukoplakia (HP:0002745)3.40052839
22Cerebral edema (HP:0002181)3.36549506
23Increased intramyocellular lipid droplets (HP:0012240)3.36084755
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.07837442
25Decreased activity of mitochondrial respiratory chain (HP:0008972)3.07837442
26Abnormality of renal resorption (HP:0011038)3.01982568
27Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.99881029
28Leukodystrophy (HP:0002415)2.90608106
29Esophageal atresia (HP:0002032)2.89724093
30Septo-optic dysplasia (HP:0100842)2.75391169
31Increased muscle lipid content (HP:0009058)2.67227758
32Respiratory failure (HP:0002878)2.64940161
333-Methylglutaconic aciduria (HP:0003535)2.61287782
34Lactic acidosis (HP:0003128)2.56999945
35Optic disc pallor (HP:0000543)2.53291699
36Pancreatic fibrosis (HP:0100732)2.50366741
37Hyperphosphaturia (HP:0003109)2.49339332
38Partial duplication of thumb phalanx (HP:0009944)2.49153126
39Delayed CNS myelination (HP:0002188)2.47249265
40Absent septum pellucidum (HP:0001331)2.41644309
41Pancreatic cysts (HP:0001737)2.40296221
42Congenital, generalized hypertrichosis (HP:0004540)2.37916356
43Exercise intolerance (HP:0003546)2.32210513
44Pallor (HP:0000980)2.31343954
45True hermaphroditism (HP:0010459)2.23301266
46Aplastic anemia (HP:0001915)2.18921061
47Abnormality of the septum pellucidum (HP:0007375)2.18624511
48Increased serum lactate (HP:0002151)2.17788778
49Abnormality of urine glucose concentration (HP:0011016)2.16929879
50Glycosuria (HP:0003076)2.16929879
51Partial duplication of the phalanx of hand (HP:0009999)2.15132296
52Renal tubular dysfunction (HP:0000124)2.12757242
53Methylmalonic acidemia (HP:0002912)2.12627362
54X-linked dominant inheritance (HP:0001423)2.11590805
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.10496652
56Nephronophthisis (HP:0000090)2.05621625
57Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.02480124
58Stenosis of the external auditory canal (HP:0000402)2.00278187
59Poor head control (HP:0002421)1.98999548
60Molar tooth sign on MRI (HP:0002419)1.98964577
61Abnormality of midbrain morphology (HP:0002418)1.98964577
62Gastrointestinal atresia (HP:0002589)1.98718828
63Birth length less than 3rd percentile (HP:0003561)1.98166172
64Thyroid-stimulating hormone excess (HP:0002925)1.95579110
65Abnormality of the parietal bone (HP:0002696)1.94081493
66Generalized aminoaciduria (HP:0002909)1.93562813
67Double outlet right ventricle (HP:0001719)1.91645066
68Congenital malformation of the right heart (HP:0011723)1.91645066
69Anencephaly (HP:0002323)1.91558618
70Cellular immunodeficiency (HP:0005374)1.91376225
71Hyperglycinemia (HP:0002154)1.87976816
72Rib fusion (HP:0000902)1.84083463
73Myokymia (HP:0002411)1.82853810
74Nephrogenic diabetes insipidus (HP:0009806)1.82336228
75Vaginal atresia (HP:0000148)1.81917427
76Lethargy (HP:0001254)1.79703561
77Aplasia/Hypoplasia of the sacrum (HP:0008517)1.78304389
78Abnormal urine phosphate concentration (HP:0012599)1.77990049
79Genital tract atresia (HP:0001827)1.77805815
80Hepatoblastoma (HP:0002884)1.76770573
81Congenital primary aphakia (HP:0007707)1.75652458
82Gait imbalance (HP:0002141)1.75390356
83Sclerocornea (HP:0000647)1.74953153
84Medial flaring of the eyebrow (HP:0010747)1.71048489
8511 pairs of ribs (HP:0000878)1.70935180
86Abnormal respiratory motile cilium physiology (HP:0012261)1.70159321
87Chronic bronchitis (HP:0004469)1.69929264
88Methylmalonic aciduria (HP:0012120)1.68192610
89Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.66188556
90Type 2 muscle fiber atrophy (HP:0003554)1.65838646
91Supernumerary spleens (HP:0009799)1.64795123
92Abnormal respiratory motile cilium morphology (HP:0005938)1.61754580
93Abnormal respiratory epithelium morphology (HP:0012253)1.61754580
94Abnormal ciliary motility (HP:0012262)1.60461129
95Depressed nasal ridge (HP:0000457)1.58102733
96Parakeratosis (HP:0001036)1.57571810
97Optic nerve hypoplasia (HP:0000609)1.57095979
98Bilateral microphthalmos (HP:0007633)1.56762785
99Hypomagnesemia (HP:0002917)1.54059051
100Amniotic constriction ring (HP:0009775)1.53847530

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.37291878
2INSRR3.55380301
3CDC73.27740878
4ZAK2.87673678
5WNK32.86098734
6PBK2.83914572
7TNIK2.55275457
8NUAK12.42978662
9BUB12.40069296
10DYRK32.39911999
11TAF12.32510177
12CASK2.24242423
13VRK12.16467028
14DYRK22.09320700
15NME12.03976274
16MST42.00036651
17TLK11.95616045
18BMPR1B1.94652841
19PLK41.86430109
20PLK31.79043918
21RPS6KA41.76118342
22MAP3K41.76100931
23TRIM281.73246842
24FGFR21.68315595
25SRPK11.63964324
26PNCK1.56668783
27TTK1.54142865
28NEK11.53701900
29STK161.36240999
30CDK81.33803458
31CAMK1G1.30061206
32MKNK21.29645948
33MKNK11.26685945
34MUSK1.20448413
35STK241.14468115
36MAP2K71.11613579
37PLK11.11032373
38PINK11.08294605
39AURKB1.02845604
40FRK1.00624494
41MAP4K20.97920074
42CHEK20.96039018
43MINK10.94653001
44MAP3K90.90813915
45CAMK1D0.88758201
46WNK40.88002493
47NEK20.86836990
48ADRBK20.86806307
49NME20.86568728
50UHMK10.86359660
51BRSK20.83793581
52CSNK1G10.74022939
53MARK10.73670387
54PLK20.72799381
55CDK30.72158843
56WEE10.71735744
57BCKDK0.70715402
58PRKCG0.69231236
59PASK0.67866999
60LRRK20.65466237
61RPS6KA50.64495448
62CAMK10.63031771
63PAK40.62499225
64CSNK2A20.61453027
65CSNK1E0.59575704
66AURKA0.58951212
67CSNK2A10.58668791
68OXSR10.56612856
69CSNK1G20.56591175
70TESK10.56262072
71SGK4940.55275373
72SGK2230.55275373
73PRKD30.54937303
74CSNK1G30.53591562
75STK30.51194122
76TSSK60.51000982
77PRKG10.46985762
78GRK10.46382395
79FGFR10.46126779
80CDK190.45008178
81ATR0.44438783
82BRSK10.43771097
83NLK0.43599580
84PRKCE0.39904354
85TYRO30.39471545
86SGK20.35820997
87CDK70.34431454
88TGFBR10.33433374
89CHEK10.32813335
90STK40.32416911
91CSNK1A10.32307270
92ATM0.31277571
93BCR0.30734277
94STK110.30605050
95PRKDC0.30103082
96PAK30.29588460
97CAMK2G0.27327381
98CDK10.26971318
99DAPK30.26415935
100CSNK1A1L0.26132702

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.37385228
2Ribosome_Homo sapiens_hsa030104.89460278
3Parkinsons disease_Homo sapiens_hsa050124.31614291
4Huntingtons disease_Homo sapiens_hsa050163.36532257
5Proteasome_Homo sapiens_hsa030503.16976566
6RNA polymerase_Homo sapiens_hsa030203.05228504
7Alzheimers disease_Homo sapiens_hsa050103.00372270
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.63758553
9Protein export_Homo sapiens_hsa030602.52984368
10Cardiac muscle contraction_Homo sapiens_hsa042602.47163751
11DNA replication_Homo sapiens_hsa030302.30791828
12Mismatch repair_Homo sapiens_hsa034302.19577395
13Spliceosome_Homo sapiens_hsa030402.12646798
14Homologous recombination_Homo sapiens_hsa034401.94661779
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.93699678
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.84298749
17Base excision repair_Homo sapiens_hsa034101.80921013
18Folate biosynthesis_Homo sapiens_hsa007901.74777179
19RNA degradation_Homo sapiens_hsa030181.61553135
20Nucleotide excision repair_Homo sapiens_hsa034201.48513115
21Pyrimidine metabolism_Homo sapiens_hsa002401.47276446
22Basal transcription factors_Homo sapiens_hsa030221.44091124
23Non-homologous end-joining_Homo sapiens_hsa034501.41282984
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.37135192
25RNA transport_Homo sapiens_hsa030131.34832146
26Collecting duct acid secretion_Homo sapiens_hsa049661.33520993
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.29843689
28Pyruvate metabolism_Homo sapiens_hsa006201.28277979
29Selenocompound metabolism_Homo sapiens_hsa004501.25486877
30One carbon pool by folate_Homo sapiens_hsa006701.16446878
31Purine metabolism_Homo sapiens_hsa002301.15916248
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.14535109
33Propanoate metabolism_Homo sapiens_hsa006401.11203757
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07531439
35Cell cycle_Homo sapiens_hsa041101.04868100
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01445585
37Fanconi anemia pathway_Homo sapiens_hsa034600.99397627
38Phototransduction_Homo sapiens_hsa047440.97915691
39Nicotine addiction_Homo sapiens_hsa050330.95732136
40Glutathione metabolism_Homo sapiens_hsa004800.90857787
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.85489222
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83969063
43Steroid biosynthesis_Homo sapiens_hsa001000.83737704
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78759511
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78504326
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.77921190
47Metabolic pathways_Homo sapiens_hsa011000.75022953
48Basal cell carcinoma_Homo sapiens_hsa052170.72994021
49Fatty acid elongation_Homo sapiens_hsa000620.67559309
50mRNA surveillance pathway_Homo sapiens_hsa030150.63826159
51Sulfur relay system_Homo sapiens_hsa041220.63820681
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61354412
53Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58200672
54Oocyte meiosis_Homo sapiens_hsa041140.57152507
55Butanoate metabolism_Homo sapiens_hsa006500.55276665
56Vitamin digestion and absorption_Homo sapiens_hsa049770.55122924
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.54925874
58Hedgehog signaling pathway_Homo sapiens_hsa043400.52328110
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51183698
60Nitrogen metabolism_Homo sapiens_hsa009100.50946675
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.50646465
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.49330637
63Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49286897
64Vibrio cholerae infection_Homo sapiens_hsa051100.48584268
65Olfactory transduction_Homo sapiens_hsa047400.48087082
66Linoleic acid metabolism_Homo sapiens_hsa005910.41936448
67Taste transduction_Homo sapiens_hsa047420.41894570
68Retinol metabolism_Homo sapiens_hsa008300.41415679
69Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40618603
70Synaptic vesicle cycle_Homo sapiens_hsa047210.38110936
71Systemic lupus erythematosus_Homo sapiens_hsa053220.37168579
72Wnt signaling pathway_Homo sapiens_hsa043100.36744828
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.36089061
74Circadian rhythm_Homo sapiens_hsa047100.35116478
75Maturity onset diabetes of the young_Homo sapiens_hsa049500.33467716
76Arginine and proline metabolism_Homo sapiens_hsa003300.31241821
77Peroxisome_Homo sapiens_hsa041460.31098142
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30722034
79Chemical carcinogenesis_Homo sapiens_hsa052040.30239614
80Notch signaling pathway_Homo sapiens_hsa043300.30063323
81Tryptophan metabolism_Homo sapiens_hsa003800.29847810
82Serotonergic synapse_Homo sapiens_hsa047260.29262400
83Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29035844
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26378675
85Biosynthesis of amino acids_Homo sapiens_hsa012300.26033711
86Carbon metabolism_Homo sapiens_hsa012000.25770182
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.25746323
88Tight junction_Homo sapiens_hsa045300.23633629
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.23318379
90Arachidonic acid metabolism_Homo sapiens_hsa005900.22158155
91p53 signaling pathway_Homo sapiens_hsa041150.21913559
92Hippo signaling pathway_Homo sapiens_hsa043900.21857898
93Epstein-Barr virus infection_Homo sapiens_hsa051690.21257908
94Alcoholism_Homo sapiens_hsa050340.19166999
95Tyrosine metabolism_Homo sapiens_hsa003500.18310106
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.15866605
97GABAergic synapse_Homo sapiens_hsa047270.14391489
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.13387096
99Morphine addiction_Homo sapiens_hsa050320.13254531
100Ether lipid metabolism_Homo sapiens_hsa005650.13131153

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