CCDC83

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.63816000
2cell wall macromolecule catabolic process (GO:0016998)9.50110622
3cell wall macromolecule metabolic process (GO:0044036)9.50110622
4reproduction (GO:0000003)9.35723972
5male meiosis (GO:0007140)9.32638073
6motile cilium assembly (GO:0044458)9.31305684
7spermatid development (GO:0007286)9.21400484
8cilium movement (GO:0003341)9.10943346
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.77593400
10regulation of cilium movement (GO:0003352)8.42093843
11synaptonemal complex organization (GO:0070193)8.27133850
12synaptonemal complex assembly (GO:0007130)8.01278866
13sperm capacitation (GO:0048240)7.64880398
14single fertilization (GO:0007338)7.61345983
15fertilization (GO:0009566)6.53109782
16DNA methylation involved in gamete generation (GO:0043046)6.50218966
17male meiosis I (GO:0007141)6.27194570
18negative regulation of inclusion body assembly (GO:0090084)6.04158388
19ventricular system development (GO:0021591)6.01405673
20spermatogenesis (GO:0007283)5.83758881
21male gamete generation (GO:0048232)5.81463515
22chromosome organization involved in meiosis (GO:0070192)5.81067879
23gamete generation (GO:0007276)5.35981648
24cellular process involved in reproduction in multicellular organism (GO:0022412)5.30585005
25germ cell development (GO:0007281)5.30353743
26response to pheromone (GO:0019236)5.29447146
27microtubule severing (GO:0051013)5.23456423
28meiotic nuclear division (GO:0007126)5.19339509
29organic cation transport (GO:0015695)5.14430193
30microtubule depolymerization (GO:0007019)5.04903606
31meiosis I (GO:0007127)5.01880148
32cell recognition (GO:0008037)4.88740667
33regulation of microtubule-based movement (GO:0060632)4.86973070
34regulation of inclusion body assembly (GO:0090083)4.83760811
35calcium ion-dependent exocytosis (GO:0017156)4.67977583
36meiotic cell cycle (GO:0051321)4.62696805
37detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.55202973
38seminiferous tubule development (GO:0072520)4.55093791
39protein localization to cilium (GO:0061512)4.52533122
40genitalia morphogenesis (GO:0035112)4.34071286
41monoubiquitinated protein deubiquitination (GO:0035520)4.30875309
42protein polyglutamylation (GO:0018095)4.25329814
43left/right pattern formation (GO:0060972)4.23592790
44cellular ketone body metabolic process (GO:0046950)4.23463543
45multicellular organismal reproductive process (GO:0048609)4.21568981
46spermatid nucleus differentiation (GO:0007289)4.16732355
47establishment of protein localization to Golgi (GO:0072600)3.98900160
48photoreceptor cell maintenance (GO:0045494)3.98606064
49ketone body metabolic process (GO:1902224)3.91211421
50intraciliary transport (GO:0042073)3.76380251
51synapsis (GO:0007129)3.75491699
52indolalkylamine metabolic process (GO:0006586)3.72420017
53gene silencing by RNA (GO:0031047)3.68720871
54regulation of pigment cell differentiation (GO:0050932)3.68130688
55negative regulation of organelle assembly (GO:1902116)3.58458962
56microtubule-based movement (GO:0007018)3.54477767
57detection of light stimulus involved in visual perception (GO:0050908)3.52293781
58detection of light stimulus involved in sensory perception (GO:0050962)3.52293781
59regulation of centriole replication (GO:0046599)3.51245921
60tryptophan catabolic process (GO:0006569)3.50731401
61indole-containing compound catabolic process (GO:0042436)3.50731401
62indolalkylamine catabolic process (GO:0046218)3.50731401
63multicellular organismal development (GO:0007275)3.45110242
64protein targeting to Golgi (GO:0000042)3.41076777
65chaperone-mediated protein complex assembly (GO:0051131)3.40353885
66auditory receptor cell stereocilium organization (GO:0060088)3.39997343
67axoneme assembly (GO:0035082)3.36687809
68meiotic cell cycle process (GO:1903046)3.33133018
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.32767396
70negative regulation of cytosolic calcium ion concentration (GO:0051481)3.32464107
71protein-chromophore linkage (GO:0018298)3.31033300
72cilium organization (GO:0044782)3.23718789
73reflex (GO:0060004)3.23149259
74carnitine transport (GO:0015879)3.22217022
75amino-acid betaine transport (GO:0015838)3.22217022
76carnitine transmembrane transport (GO:1902603)3.22139920
77glycerol ether metabolic process (GO:0006662)3.17854637
78retrograde transport, vesicle recycling within Golgi (GO:0000301)3.17492305
79behavioral response to ethanol (GO:0048149)3.16327618
80inner ear receptor stereocilium organization (GO:0060122)3.14904306
81kynurenine metabolic process (GO:0070189)3.12729673
82neural tube formation (GO:0001841)3.10566238
83chromosome condensation (GO:0030261)3.06056523
84cilium assembly (GO:0042384)3.04882409
85alditol metabolic process (GO:0019400)3.02228421
86meiotic chromosome segregation (GO:0045132)2.98599296
87cellular component assembly involved in morphogenesis (GO:0010927)2.98486356
88reciprocal meiotic recombination (GO:0007131)2.98275204
89reciprocal DNA recombination (GO:0035825)2.98275204
90DNA packaging (GO:0006323)2.95429382
91regulation of spindle checkpoint (GO:0090231)2.92555640
92peptidyl-glutamic acid modification (GO:0018200)2.92234622
93ether metabolic process (GO:0018904)2.91941992
94centriole assembly (GO:0098534)2.91374084
95phosphatidylethanolamine metabolic process (GO:0046337)2.90953116
96phosphatidylethanolamine biosynthetic process (GO:0006646)2.90060324
97centriole replication (GO:0007099)2.89434911
98negative regulation of mast cell activation (GO:0033004)2.87668723
99negative regulation of cAMP-mediated signaling (GO:0043951)2.86078229
100tachykinin receptor signaling pathway (GO:0007217)2.85192993
101regulation of sarcomere organization (GO:0060297)2.83768097
102tryptophan metabolic process (GO:0006568)2.83535781
103nucleoside diphosphate phosphorylation (GO:0006165)2.83179997
104C4-dicarboxylate transport (GO:0015740)2.82432161
105cilium morphogenesis (GO:0060271)2.80604042
106fucose catabolic process (GO:0019317)2.79433937
107L-fucose metabolic process (GO:0042354)2.79433937
108L-fucose catabolic process (GO:0042355)2.79433937
109primary amino compound metabolic process (GO:1901160)2.78978803
110protein localization to Golgi apparatus (GO:0034067)2.77881739
111lactate metabolic process (GO:0006089)2.75300283
112detection of mechanical stimulus involved in sensory perception (GO:0050974)2.75283323
113sphingoid metabolic process (GO:0046519)2.75275758
114positive regulation of meiosis (GO:0045836)2.75151991
115NAD biosynthetic process (GO:0009435)2.75049404
116regulation of establishment of cell polarity (GO:2000114)2.73912019
117indole-containing compound metabolic process (GO:0042430)2.72774145
118protein refolding (GO:0042026)2.72740900
119regulation of meiosis I (GO:0060631)2.70267735
120protein K11-linked deubiquitination (GO:0035871)2.69171954
121glycerol metabolic process (GO:0006071)2.69031362
122nuclear pore complex assembly (GO:0051292)2.66190442
123glycolytic process (GO:0006096)2.66184154
124regulation of acrosome reaction (GO:0060046)2.63130696
125RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.59896661
126positive regulation of developmental pigmentation (GO:0048087)2.59153167
127proline transport (GO:0015824)2.58354422
128gene silencing (GO:0016458)2.58168175
129polyol catabolic process (GO:0046174)2.57971956
130positive regulation of meiotic cell cycle (GO:0051446)2.57726391
131microtubule polymerization or depolymerization (GO:0031109)2.54084202
132retinal cone cell development (GO:0046549)2.53681312
133nucleus organization (GO:0006997)2.53456136
134tyrosine phosphorylation of STAT protein (GO:0007260)2.52916158
135positive regulation of Rab GTPase activity (GO:0032851)2.52313690
136regulation of Rab GTPase activity (GO:0032313)2.52313690
137single strand break repair (GO:0000012)2.50924068
138regulation of protein polyubiquitination (GO:1902914)2.48863514
139mitotic sister chromatid cohesion (GO:0007064)2.44749821
140sex differentiation (GO:0007548)2.41728556
141GTP biosynthetic process (GO:0006183)2.38807117
142left/right axis specification (GO:0070986)2.34790867
143DNA alkylation (GO:0006305)2.34321961
144cilium or flagellum-dependent cell motility (GO:0001539)16.8431836
145fusion of sperm to egg plasma membrane (GO:0007342)12.7211606
146sperm motility (GO:0030317)12.6405425
147multicellular organism reproduction (GO:0032504)11.4675907
148axonemal dynein complex assembly (GO:0070286)11.3468631
149sperm-egg recognition (GO:0035036)11.3399857
150acrosome assembly (GO:0001675)11.2348883
151acrosome reaction (GO:0007340)10.6356311
152piRNA metabolic process (GO:0034587)10.5979651
153binding of sperm to zona pellucida (GO:0007339)10.2929605
154cell-cell recognition (GO:0009988)10.1461131
155epithelial cilium movement (GO:0003351)10.0857368

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.87525114
2EZH2_22144423_ChIP-Seq_EOC_Human5.83553320
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.27706947
4GBX2_23144817_ChIP-Seq_PC3_Human3.41489776
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.31103967
6IGF1R_20145208_ChIP-Seq_DFB_Human3.23002911
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.79254527
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.56406966
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.52466097
10* TAF15_26573619_Chip-Seq_HEK293_Human2.50814897
11FUS_26573619_Chip-Seq_HEK293_Human2.44027231
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.41494428
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.34348833
14PCGF2_27294783_Chip-Seq_ESCs_Mouse2.28799047
15P300_19829295_ChIP-Seq_ESCs_Human2.24923488
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.23132257
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.22931781
18SALL1_21062744_ChIP-ChIP_HESCs_Human2.22415901
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.15249799
20AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.10588749
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.07324778
22VDR_22108803_ChIP-Seq_LS180_Human1.99572634
23SMAD4_21799915_ChIP-Seq_A2780_Human1.95597205
24PCGF2_27294783_Chip-Seq_NPCs_Mouse1.92694413
25GATA1_26923725_Chip-Seq_HPCs_Mouse1.92487610
26STAT3_23295773_ChIP-Seq_U87_Human1.91174025
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.87983618
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.86650220
29EWS_26573619_Chip-Seq_HEK293_Human1.85161558
30ZNF274_21170338_ChIP-Seq_K562_Hela1.80252906
31CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.76693507
32BCAT_22108803_ChIP-Seq_LS180_Human1.75986720
33ELK4_26923725_Chip-Seq_MESODERM_Mouse1.74334819
34NFE2_27457419_Chip-Seq_LIVER_Mouse1.73340166
35AR_25329375_ChIP-Seq_VCAP_Human1.72300778
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.66520013
37STAT1_17558387_ChIP-Seq_HELA_Human1.65831175
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.64235993
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.63854420
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.63200432
41TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.62399907
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60367022
43KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.60221676
44NR3C1_21868756_ChIP-Seq_MCF10A_Human1.58441843
45* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57827479
46TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51711350
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.51654840
48TAL1_26923725_Chip-Seq_HPCs_Mouse1.50366811
49KAP1_22055183_ChIP-Seq_ESCs_Mouse1.48944689
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.48249237
51CBP_20019798_ChIP-Seq_JUKART_Human1.46667449
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46667449
53WDR5_24793694_ChIP-Seq_LNCAP_Human1.44320122
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43963875
55RUNX2_22187159_ChIP-Seq_PCA_Human1.43678194
56* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.43636403
57GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.41771892
58TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41344855
59TCF4_22108803_ChIP-Seq_LS180_Human1.40831710
60KDM2B_26808549_Chip-Seq_REH_Human1.40730471
61SOX2_19829295_ChIP-Seq_ESCs_Human1.40123320
62NANOG_19829295_ChIP-Seq_ESCs_Human1.40123320
63SMAD4_21741376_ChIP-Seq_EPCs_Human1.37869917
64SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36081567
65TP53_22573176_ChIP-Seq_HFKS_Human1.35566773
66CRX_20693478_ChIP-Seq_RETINA_Mouse1.34089768
67RNF2_27304074_Chip-Seq_NSC_Mouse1.33912416
68OCT4_18555785_Chip-Seq_ESCs_Mouse1.32902807
69CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32250338
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.31458066
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31449290
72EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.31014137
73EZH2_27294783_Chip-Seq_NPCs_Mouse1.31009940
74PRDM14_20953172_ChIP-Seq_ESCs_Human1.30897922
75ARNT_22903824_ChIP-Seq_MCF-7_Human1.30878698
76* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30685523
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.29499122
78MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29490399
79* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.29350023
80CDX2_22108803_ChIP-Seq_LS180_Human1.29119271
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28412027
82RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27629052
83AR_21572438_ChIP-Seq_LNCaP_Human1.27303699
84REST_21632747_ChIP-Seq_MESCs_Mouse1.24754176
85P53_22387025_ChIP-Seq_ESCs_Mouse1.24328751
86* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23637731
87FLI1_21867929_ChIP-Seq_TH2_Mouse1.22205023
88OCT4_21477851_ChIP-Seq_ESCs_Mouse1.21346661
89P300_18555785_Chip-Seq_ESCs_Mouse1.21253065
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.21015077
91SMAD_19615063_ChIP-ChIP_OVARY_Human1.19251232
92GATA3_21867929_ChIP-Seq_CD8_Mouse1.19125722
93* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.18296063
94EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.18187950
95SOX2_22085726_ChIP-Seq_NPCs_Mouse1.17885490
96GATA3_21867929_ChIP-Seq_TH1_Mouse1.16955812
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16914081
98AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16252329
99KLF4_18555785_Chip-Seq_ESCs_Mouse1.16196177
100STAT3_18555785_Chip-Seq_ESCs_Mouse1.16167196
101TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15987559
102CMYC_18555785_Chip-Seq_ESCs_Mouse1.15538322
103TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15506506
104GF1_26923725_Chip-Seq_HPCs_Mouse1.15188375
105* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.15029686
106* FOXA1_25329375_ChIP-Seq_VCAP_Human1.15029686
107RAD21_21589869_ChIP-Seq_MESCs_Mouse1.14971922
108AHR_22903824_ChIP-Seq_MCF-7_Human1.14623998
109LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.12968350
110SUZ12_18555785_Chip-Seq_ESCs_Mouse1.12866896
111SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.12626328
112CTBP2_25329375_ChIP-Seq_LNCAP_Human1.12607431
113ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11781361
114MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10552269
115ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.09162800
116ESR1_20079471_ChIP-ChIP_T-47D_Human1.08912127
117PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.08242735
118RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08021429
119TP53_18474530_ChIP-ChIP_U2OS_Human1.07070208
120PU1_27457419_Chip-Seq_LIVER_Mouse1.07021033
121* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05910210
122* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05910210
123RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05863854
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04163402
125NCOR_22424771_ChIP-Seq_293T_Human1.03804952
126CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03708268
127CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03544151
128PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.03387302
129ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02982656
130P53_21459846_ChIP-Seq_SAOS-2_Human1.02972321
131E2F1_18555785_Chip-Seq_ESCs_Mouse1.02265447
132FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01088345
133SOX2_21211035_ChIP-Seq_LN229_Gbm1.00275972
134* CJUN_26792858_Chip-Seq_BT549_Human0.99524398
135HOXB7_26014856_ChIP-Seq_BT474_Human0.98640355
136GATA3_21878914_ChIP-Seq_MCF-7_Human0.98559930
137CTCF_18555785_Chip-Seq_ESCs_Mouse0.98435052
138SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.98138913
139EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97763344
140ZFX_18555785_Chip-Seq_ESCs_Mouse0.96593596
141GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96486910
142NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.96120689
143SOX2_18555785_Chip-Seq_ESCs_Mouse0.95199674
144NMYC_18555785_Chip-Seq_ESCs_Mouse0.95073801
145EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94125115
146SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94061660
147SMAD1_18555785_Chip-Seq_ESCs_Mouse0.93966192
148ESET_19884257_ChIP-Seq_ESCs_Mouse0.93434289
149SPI1_26923725_Chip-Seq_HPCs_Mouse0.92588952
150PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91658169
151ER_23166858_ChIP-Seq_MCF-7_Human0.90016613
152TCF4_23295773_ChIP-Seq_U87_Human0.89330634
153PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88867462
154EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.87655021
155RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.87105695
156TBL1_22424771_ChIP-Seq_293T_Human0.85304374
157ERG_20517297_ChIP-Seq_VCAP_Human0.85231403
158* NFYB_21822215_ChIP-Seq_K562_Human0.84416840
159MYC_27129775_Chip-Seq_CORNEA_Mouse0.84374937

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.97188709
2MP0001929_abnormal_gametogenesis5.40418218
3MP0008877_abnormal_DNA_methylation4.87827918
4MP0002653_abnormal_ependyma_morphology4.03010095
5MP0002210_abnormal_sex_determination3.79835051
6MP0005623_abnormal_meninges_morphology3.74660998
7MP0002161_abnormal_fertility/fecundity3.20701614
8MP0001145_abnormal_male_reproductive3.12698891
9MP0001968_abnormal_touch/_nociception2.81985779
10MP0000653_abnormal_sex_gland2.71935021
11MP0005174_abnormal_tail_pigmentation2.11077397
12MP0000383_abnormal_hair_follicle2.04207197
13MP0001501_abnormal_sleep_pattern2.00398060
14MP0005410_abnormal_fertilization15.2596476
15MP0002837_dystrophic_cardiac_calcinosis1.95018009
16MP0003195_calcinosis1.94149016
17MP0000372_irregular_coat_pigmentation1.88907702
18MP0003136_yellow_coat_color1.88354110
19MP0002638_abnormal_pupillary_reflex1.88233161
20MP0002138_abnormal_hepatobiliary_system1.86422079
21MP0002160_abnormal_reproductive_system1.82365212
22MP0003880_abnormal_central_pattern1.76495952
23MP0000015_abnormal_ear_pigmentation1.76352030
24MP0002876_abnormal_thyroid_physiology1.73477826
25MP0006276_abnormal_autonomic_nervous1.72296006
26MP0004043_abnormal_pH_regulation1.71778361
27MP0009046_muscle_twitch1.70502637
28MP0001486_abnormal_startle_reflex1.68090038
29MP0005085_abnormal_gallbladder_physiolo1.66409944
30MP0002282_abnormal_trachea_morphology1.62448333
31MP0009745_abnormal_behavioral_response1.56352176
32MP0001485_abnormal_pinna_reflex1.54455222
33MP0005646_abnormal_pituitary_gland1.51901155
34MP0008057_abnormal_DNA_replication1.51635806
35MP0010678_abnormal_skin_adnexa1.50879673
36MP0003646_muscle_fatigue1.45748542
37MP0009697_abnormal_copulation1.43842494
38MP0005670_abnormal_white_adipose1.42976830
39MP0002735_abnormal_chemical_nociception1.40448528
40MP0008872_abnormal_physiological_respon1.39607937
41MP0002272_abnormal_nervous_system1.36795382
42MP0008058_abnormal_DNA_repair1.34504016
43MP0006072_abnormal_retinal_apoptosis1.34375138
44MP0010386_abnormal_urinary_bladder1.29682318
45MP0005187_abnormal_penis_morphology1.27964785
46MP0005171_absent_coat_pigmentation1.24914177
47MP0003252_abnormal_bile_duct1.23975172
48MP0005647_abnormal_sex_gland1.20332349
49MP0002095_abnormal_skin_pigmentation1.19915532
50MP0005645_abnormal_hypothalamus_physiol1.19490907
51MP0005167_abnormal_blood-brain_barrier1.19401434
52MP0003718_maternal_effect1.17903713
53MP0005075_abnormal_melanosome_morpholog1.14812306
54MP0002938_white_spotting1.11331779
55MP0004147_increased_porphyrin_level1.08051082
56MP0005310_abnormal_salivary_gland1.06785507
57MP0003011_delayed_dark_adaptation1.06088870
58MP0003950_abnormal_plasma_membrane1.05650318
59MP0005386_behavior/neurological_phenoty1.04198781
60MP0004924_abnormal_behavior1.04198781
61MP0001984_abnormal_olfaction1.03935739
62MP0001970_abnormal_pain_threshold1.00564973
63MP0001765_abnormal_ion_homeostasis0.99346562
64MP0002733_abnormal_thermal_nociception0.97938275
65MP0006054_spinal_hemorrhage0.94407358
66MP0002572_abnormal_emotion/affect_behav0.93549957
67MP0002557_abnormal_social/conspecific_i0.92136636
68MP0009780_abnormal_chondrocyte_physiolo0.91652833
69MP0000631_abnormal_neuroendocrine_gland0.91423125
70MP0002067_abnormal_sensory_capabilities0.89914373
71MP0005379_endocrine/exocrine_gland_phen0.88818000
72MP0005365_abnormal_bile_salt0.88647863
73MP0003937_abnormal_limbs/digits/tail_de0.87787846
74MP0005389_reproductive_system_phenotype0.87481222
75MP0010094_abnormal_chromosome_stability0.86995580
76MP0000371_diluted_coat_color0.86420626
77MP0002254_reproductive_system_inflammat0.84288792
78MP0002064_seizures0.82300643
79MP0008875_abnormal_xenobiotic_pharmacok0.82066433
80MP0001963_abnormal_hearing_physiology0.81006845
81MP0001919_abnormal_reproductive_system0.80090354
82MP0002822_catalepsy0.79837817
83MP0003635_abnormal_synaptic_transmissio0.79718879
84MP0010329_abnormal_lipoprotein_level0.78449321
85MP0000538_abnormal_urinary_bladder0.77974786
86MP0006082_CNS_inflammation0.77782732
87MP0002127_abnormal_cardiovascular_syste0.77626528
88MP0004215_abnormal_myocardial_fiber0.77059642
89MP0002184_abnormal_innervation0.75166574
90MP0008995_early_reproductive_senescence0.73772016
91MP0004233_abnormal_muscle_weight0.64292007
92MP0001293_anophthalmia0.62633659
93MP0000569_abnormal_digit_pigmentation0.62448911
94MP0000427_abnormal_hair_cycle0.60629354
95MP0002928_abnormal_bile_duct0.60170398
96MP0008007_abnormal_cellular_replicative0.57495146
97MP0003329_amyloid_beta_deposits0.52687149
98MP0009278_abnormal_bone_marrow0.52667003
99MP0003786_premature_aging0.52620040
100MP0004134_abnormal_chest_morphology0.52496655
101MP0001727_abnormal_embryo_implantation0.51045916
102MP0005451_abnormal_body_composition0.47862240
103MP0004019_abnormal_vitamin_homeostasis0.47692504
104MP0005551_abnormal_eye_electrophysiolog0.47301384
105MP0005636_abnormal_mineral_homeostasis0.45202339
106MP0003699_abnormal_female_reproductive0.44612513
107MP0003878_abnormal_ear_physiology0.44451952
108MP0005377_hearing/vestibular/ear_phenot0.44451952
109MP0000358_abnormal_cell_content/0.44091783
110MP0005253_abnormal_eye_physiology0.42225629
111MP0003115_abnormal_respiratory_system0.42075603
112MP0005391_vision/eye_phenotype0.41968531
113MP0001119_abnormal_female_reproductive0.41444402
114MP0003690_abnormal_glial_cell0.41054796
115MP0001324_abnormal_eye_pigmentation0.38637346
116MP0004133_heterotaxia0.36560555
117MP0005397_hematopoietic_system_phenotyp0.36515742
118MP0001545_abnormal_hematopoietic_system0.36515742
119MP0002092_abnormal_eye_morphology0.36404324
120MP0004036_abnormal_muscle_relaxation0.36137423
121MP0000751_myopathy0.33864316
122MP0002234_abnormal_pharynx_morphology0.32360297
123MP0003633_abnormal_nervous_system0.31952968
124MP0002108_abnormal_muscle_morphology0.31715500
125MP0000647_abnormal_sebaceous_gland0.31533796
126MP0004808_abnormal_hematopoietic_stem0.30271363
127MP0002796_impaired_skin_barrier0.29757111
128MP0000920_abnormal_myelination0.28616944
129MP0002295_abnormal_pulmonary_circulatio0.27392002
130MP0001851_eye_inflammation0.27283269
131MP0001529_abnormal_vocalization0.25838013
132MP0003631_nervous_system_phenotype0.25235706
133MP0005388_respiratory_system_phenotype0.24410385
134MP0002133_abnormal_respiratory_system0.24410385
135MP0002152_abnormal_brain_morphology0.24061329
136MP0001764_abnormal_homeostasis0.24041495
137MP0003861_abnormal_nervous_system0.23790266
138MP0004885_abnormal_endolymph0.23407727
139MP0010307_abnormal_tumor_latency0.23148670
140MP0003111_abnormal_nucleus_morphology0.21951918
141MP0005666_abnormal_adipose_tissue0.20733824
142MP0002102_abnormal_ear_morphology0.20652897
143MP0003045_fibrosis0.19448923
144MP0002132_abnormal_respiratory_system0.19184366
145MP0000604_amyloidosis0.19160817
146MP0002971_abnormal_brown_adipose0.19131775
147MP0000313_abnormal_cell_death0.18452489
148MP0006138_congestive_heart_failure0.18085328
149MP0000462_abnormal_digestive_system0.17335951
150MP0001730_embryonic_growth_arrest0.16949190
151MP0003634_abnormal_glial_cell0.16837510
152MP0002269_muscular_atrophy0.16232981
153MP0002229_neurodegeneration0.16098761
154MP0003936_abnormal_reproductive_system0.15559661
155MP0002697_abnormal_eye_size0.15286993
156MP0003942_abnormal_urinary_system0.14722776
157MP0001986_abnormal_taste_sensitivity0.14682309
158MP0002736_abnormal_nociception_after0.14538927
159MP0000432_abnormal_head_morphology0.14506330
160MP0009115_abnormal_fat_cell0.14120276
161MP0004811_abnormal_neuron_physiology0.13807729
162MP0002169_no_abnormal_phenotype0.13627039
163MP0004270_analgesia0.13542636
164MP0005195_abnormal_posterior_eye0.13424574

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.57074598
2Abnormal respiratory motile cilium morphology (HP:0005938)8.72088994
3Abnormal respiratory epithelium morphology (HP:0012253)8.72088994
4Abnormal ciliary motility (HP:0012262)8.02773674
5Rhinitis (HP:0012384)7.78380295
6Chronic bronchitis (HP:0004469)6.85760646
7Nasal polyposis (HP:0100582)6.42177891
8Infertility (HP:0000789)6.22855890
9Abnormality of the nasal mucosa (HP:0000433)5.30899907
10Pancreatic cysts (HP:0001737)4.77123920
11Bronchiectasis (HP:0002110)4.76711879
12Nephronophthisis (HP:0000090)4.54757719
13Bronchitis (HP:0012387)4.53737592
14Attenuation of retinal blood vessels (HP:0007843)4.17410481
15Chronic hepatic failure (HP:0100626)4.09015945
16Recurrent sinusitis (HP:0011108)3.58023549
17Abnormality of the renal medulla (HP:0100957)3.52632171
18Congenital stationary night blindness (HP:0007642)3.51590022
19Recurrent otitis media (HP:0000403)3.49494176
20Male infertility (HP:0003251)3.46517799
21Bony spicule pigmentary retinopathy (HP:0007737)3.32357532
22Volvulus (HP:0002580)3.25574012
23Hyperventilation (HP:0002883)3.25356856
24Gaze-evoked nystagmus (HP:0000640)3.23491087
25Abnormality of the lower motor neuron (HP:0002366)3.17606965
26Genetic anticipation (HP:0003743)3.08611080
27Recurrent bronchitis (HP:0002837)2.99055555
28Renal cortical cysts (HP:0000803)2.94003909
29Abnormality of macular pigmentation (HP:0008002)2.89618551
30Abnormal spermatogenesis (HP:0008669)2.89312576
31Tubulointerstitial nephritis (HP:0001970)2.88800559
32Abnormal rod and cone electroretinograms (HP:0008323)2.88512118
33Progressive cerebellar ataxia (HP:0002073)2.88408510
34Cerebellar dysplasia (HP:0007033)2.87516567
35Severe visual impairment (HP:0001141)2.84900103
36Gonadotropin excess (HP:0000837)2.79683691
37Abnormality of midbrain morphology (HP:0002418)2.65971215
38Molar tooth sign on MRI (HP:0002419)2.65971215
39Absent speech (HP:0001344)2.65540767
40Type II lissencephaly (HP:0007260)2.64246591
41Tubular atrophy (HP:0000092)2.59965508
42Febrile seizures (HP:0002373)2.57732241
43Tubulointerstitial abnormality (HP:0001969)2.53539980
44Abolished electroretinogram (ERG) (HP:0000550)2.50676979
45Congenital sensorineural hearing impairment (HP:0008527)2.49807067
46Amyotrophic lateral sclerosis (HP:0007354)2.46407655
47Progressive inability to walk (HP:0002505)2.46153993
48Keratoconus (HP:0000563)2.43801836
49Increased corneal curvature (HP:0100692)2.43801836
50Inability to walk (HP:0002540)2.43749805
51Sclerocornea (HP:0000647)2.42586176
52Postaxial foot polydactyly (HP:0001830)2.39404231
53Congenital primary aphakia (HP:0007707)2.35397877
54Gait imbalance (HP:0002141)2.34031195
55Medial flaring of the eyebrow (HP:0010747)2.32507215
56Absent rod-and cone-mediated responses on ERG (HP:0007688)2.32353594
57Fibular hypoplasia (HP:0003038)2.31755494
58Hyperkalemia (HP:0002153)2.25650799
59Focal seizures (HP:0007359)2.23743143
60Protruding tongue (HP:0010808)2.21894769
61Microglossia (HP:0000171)2.19505761
62Dialeptic seizures (HP:0011146)2.19298173
63Hypothermia (HP:0002045)2.19231629
64Fair hair (HP:0002286)2.18436256
65Nephrogenic diabetes insipidus (HP:0009806)2.17241697
66Pendular nystagmus (HP:0012043)2.16944654
67Azoospermia (HP:0000027)2.13545441
68Stomach cancer (HP:0012126)2.12512707
69Tubulointerstitial fibrosis (HP:0005576)2.11426449
70Amelogenesis imperfecta (HP:0000705)2.11016327
71Stage 5 chronic kidney disease (HP:0003774)2.09529340
72Choroideremia (HP:0001139)2.09222854
73Congenital hepatic fibrosis (HP:0002612)2.08906222
74Absent frontal sinuses (HP:0002688)2.08613235
75Aplasia/Hypoplasia of the tibia (HP:0005772)2.07499239
76Impulsivity (HP:0100710)2.07433856
77Occipital encephalocele (HP:0002085)2.07362105
78Genital tract atresia (HP:0001827)2.06098704
79Intestinal atresia (HP:0011100)2.05761053
80Methylmalonic acidemia (HP:0002912)2.04461253
81Small hand (HP:0200055)2.04399673
82Abnormal glycosylation (HP:0012345)2.02859678
83Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.02859678
84Abnormal protein N-linked glycosylation (HP:0012347)2.02859678
85Abnormal protein glycosylation (HP:0012346)2.02859678
86Abnormal drinking behavior (HP:0030082)2.02219399
87Polydipsia (HP:0001959)2.02219399
88Impaired proprioception (HP:0010831)2.02161730
89Anencephaly (HP:0002323)2.02127488
90J-shaped sella turcica (HP:0002680)2.01655985
91Respiratory insufficiency due to defective ciliary clearance (HP:0200073)14.2360681
92Dynein arm defect of respiratory motile cilia (HP:0012255)12.6259693
93Absent/shortened dynein arms (HP:0200106)12.6259693
94Hypoplasia of the capital femoral epiphysis (HP:0003090)1.99785754
95Methylmalonic aciduria (HP:0012120)1.99186942
96Horizontal nystagmus (HP:0000666)1.98940282
97Astigmatism (HP:0000483)1.96247460
98Hypoplasia of the fovea (HP:0007750)1.94564589
99Aplasia/Hypoplasia of the fovea (HP:0008060)1.94564589
100Vaginal atresia (HP:0000148)1.94462089
101Abnormality of the renal cortex (HP:0011035)1.91457108
102Potter facies (HP:0002009)1.88679826
103Facial shape deformation (HP:0011334)1.88679826
104Prostate neoplasm (HP:0100787)1.88346251
105Male pseudohermaphroditism (HP:0000037)1.87701323
106Proximal tubulopathy (HP:0000114)1.86446215
107Short ribs (HP:0000773)1.86354769
108Widely spaced teeth (HP:0000687)1.84416650
109Spastic tetraparesis (HP:0001285)1.84409385
110Hypoplastic iliac wings (HP:0002866)1.83803664
111Retinitis pigmentosa (HP:0000510)1.82740366
112Median cleft lip (HP:0000161)1.82207748
113Upper motor neuron abnormality (HP:0002127)1.81359244
114Furrowed tongue (HP:0000221)1.80870199
115Taurodontia (HP:0000679)1.80235380
116Abnormality of permanent molar morphology (HP:0011071)1.80235380
117Abnormality of the dental root (HP:0006486)1.80235380
118Renal dysplasia (HP:0000110)1.79006407
119Focal motor seizures (HP:0011153)1.77599430
120Bile duct proliferation (HP:0001408)1.77283272
121Abnormal biliary tract physiology (HP:0012439)1.77283272
122Poor coordination (HP:0002370)1.76351288
123Atonic seizures (HP:0010819)1.75798449
124Facial cleft (HP:0002006)1.75701810
125Constricted visual fields (HP:0001133)1.75432986
126Metaphyseal dysplasia (HP:0100255)1.74831461
127Colon cancer (HP:0003003)1.74593894
128Supernumerary spleens (HP:0009799)1.70259366
129Oculomotor apraxia (HP:0000657)1.70244698
130Abnormality of molar (HP:0011077)1.69904291
131Abnormality of molar morphology (HP:0011070)1.69904291
132Abnormality of renal excretion (HP:0011036)1.67995180
133Abnormality of the dental pulp (HP:0006479)1.63331849
134Abnormality of dentin (HP:0010299)1.62398444
135Aplasia/Hypoplasia of the tongue (HP:0010295)1.61853294
136Chronic sinusitis (HP:0011109)1.60584613
137Postaxial hand polydactyly (HP:0001162)1.58406758
138Pancreatic fibrosis (HP:0100732)1.57989622
139Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.57321173
140Absent epiphyses (HP:0010577)1.57321173
141Short thorax (HP:0010306)1.55718349
142Bell-shaped thorax (HP:0001591)1.50908251
143Nephropathy (HP:0000112)1.49800097
144Decreased central vision (HP:0007663)1.49400083
145Abnormality of the anterior horn cell (HP:0006802)1.48837792
146Degeneration of anterior horn cells (HP:0002398)1.48837792
147Abnormal gallbladder physiology (HP:0012438)1.48146563
148Cholecystitis (HP:0001082)1.48146563
149True hermaphroditism (HP:0010459)1.47518975
150Heterotopia (HP:0002282)1.47241077
151Aplasia/Hypoplasia of the fibula (HP:0006492)1.46842865
152Deformed sella turcica (HP:0002681)1.45838686
153Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.45121136
154Cystic liver disease (HP:0006706)1.44831611
155Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.40945381
156Abnormal urine output (HP:0012590)1.36085177
157Neurofibrillary tangles (HP:0002185)1.33001658
158Polyuria (HP:0000103)1.29276686
159Decreased motor nerve conduction velocity (HP:0003431)1.29114999
160Broad distal phalanx of finger (HP:0009836)1.28336711
161Vascular calcification (HP:0004934)1.27894147
162Dyschromatopsia (HP:0007641)1.27423933
163Pachygyria (HP:0001302)1.26676426
164Nephroblastoma (Wilms tumor) (HP:0002667)1.23684310
165Short femoral neck (HP:0100864)1.20788326
166Aplasia/Hypoplasia of the lens (HP:0008063)1.19867920
167Bundle branch block (HP:0011710)1.18786724
168Abnormality of the frontal sinuses (HP:0002687)1.17588923
169Cardiovascular calcification (HP:0011915)1.17005098
170Abnormality of the sella turcica (HP:0002679)1.15547140
171Embryonal renal neoplasm (HP:0011794)1.15023673

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.55534368
2PDK48.55534368
3FRK6.76103396
4PDK25.48082133
5TESK14.58210085
6STK393.71554576
7PRKD33.48646664
8WNK43.46180648
9ICK3.27519796
10MAP4K23.02656990
11NEK12.95498081
12PTK2B2.66008997
13PNCK2.65151739
14INSRR2.54712591
15NUAK12.33312871
16PLK22.04624269
17LATS12.02208578
18ACVR1B2.00944426
19MAPK131.94628618
20CASK1.92229246
21WNK11.70843035
22NEK21.70020747
23EIF2AK31.69480243
24TRIM281.55993007
25STK381.42354116
26ZAK1.33728202
27AKT31.31309818
28MAPK151.29559170
29MET1.24144127
30FER1.19867962
31ERBB31.14400895
32PRKCE1.13168540
33BCR1.12110403
34CDK191.01391533
35PIK3CG1.00348024
36PIK3CA0.97089094
37PDK10.94285178
38STK30.93328099
39CSNK1G10.92617343
40TYRO30.92286318
41CSNK1A1L0.92028012
42DYRK1B0.89972900
43CSNK1G20.89132350
44TXK0.88250277
45BMPR1B0.88025841
46TNK20.87240912
47BRD40.86254428
48CDC70.84359336
49EPHA40.82090235
50MAPKAPK30.79091284
51NTRK30.78276319
52PASK0.77108682
53TTK0.76793748
54CSNK1G30.75573972
55TAF10.73875377
56CCNB10.72152980
57PAK30.71569499
58ADRBK10.71284236
59IRAK10.68886721
60MKNK20.67666307
61MAP3K120.66519922
62PINK10.66054444
63MAP3K90.58463719
64STK38L0.58184383
65WEE10.58010885
66DYRK30.54296571
67TAOK30.53405913
68CAMK1G0.53333874
69LMTK20.53276119
70MUSK0.52546978
71CHEK20.51428137
72MARK10.49957007
73CHEK10.49732624
74ATR0.46354032
75PRKAA20.44706633
76FLT30.42352522
77CDK30.41983971
78ROCK10.41379637
79DAPK20.40700691
80OBSCN0.39384305
81PDPK10.37130095
82TEC0.36516566
83PRKCG0.36016084
84GRK10.35783867
85CAMK10.34824876
86ATM0.33955728
87MST40.33561350
88DYRK1A0.32854840
89TNIK0.32371891
90IRAK20.31694427
91TGFBR10.31533168
92MAP3K70.30689411
93OXSR10.30497646
94ADRBK20.30418475
95BMPR20.30406831
96PRKACA0.30112415
97MAPKAPK50.29936156
98NTRK20.29555941
99PAK10.29101795
100PRKCQ0.28084683
101MAP2K70.27946459
102PAK20.27086073
103EEF2K0.26478502
104PRKG20.26406415
105IGF1R0.26246741
106CSNK1A10.25604547
107MAP2K60.25507885
108PLK10.25478702
109YES10.24698401
110CSK0.24633761
111PRKCI0.24407576
112NEK60.23716405
113MKNK10.23662270
114MAP2K40.22634279
115ABL10.21918818
116DDR20.21542681
117EGFR0.21526925
118MTOR0.19295205
119MINK10.18547349
120SGK20.18502992
121MAP3K60.18498853
122TESK20.17874418
123RIPK40.17480830
124ZAP700.17449509
125PAK60.15910914
126CDK120.15898164
127MARK20.13435330
128GRK70.13319325
129MAP3K40.13252940
130RPS6KB10.12714505
131PKN10.12623869
132PRKAA10.12129881
133TAOK10.12079241
134STK110.11679572
135PRKCZ0.10929477
136CSNK1D0.08865559
137PLK40.08865199
138PRKG10.08264852
139EIF2AK20.07504201
140CDK10.07224711
141CAMK2A0.07115504
142WNK30.06877785
143CDK150.05777624
144GSK3B0.05701622
145PDGFRB0.05430118
146STK100.04447015
147CSNK2A10.04351568
148MAPK80.04017381
149PRKACB0.03742894
150STK160.03715934
151PRKCB0.03291913
152CDK180.03197768
153EPHB20.03165537
154PRKACG0.02941626
155PRKDC0.02474952
156CDK140.02411939
157CSNK2A20.02017713
158CDK11A0.01638258
159CAMKK10.01257947
160PRKCA0.00902301
161CDK20.00488459
162AURKA0.00379316
163CSF1R0.00105567
164RPS6KA3-0.0147597
165EPHB1-0.0053411
166PRKCD-0.0005675

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.13953251
2Vitamin B6 metabolism_Homo sapiens_hsa007504.08876264
3Pyruvate metabolism_Homo sapiens_hsa006203.79834849
4Propanoate metabolism_Homo sapiens_hsa006403.64117183
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.61802285
6Fatty acid biosynthesis_Homo sapiens_hsa000613.60363523
7Primary bile acid biosynthesis_Homo sapiens_hsa001203.08526248
8Dorso-ventral axis formation_Homo sapiens_hsa043203.07470443
9Butanoate metabolism_Homo sapiens_hsa006502.96597755
10Basal transcription factors_Homo sapiens_hsa030222.88882079
11Pentose phosphate pathway_Homo sapiens_hsa000302.81340930
12Phototransduction_Homo sapiens_hsa047442.77004086
13Fanconi anemia pathway_Homo sapiens_hsa034602.74140281
14Glucagon signaling pathway_Homo sapiens_hsa049222.63808365
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.60718373
16Linoleic acid metabolism_Homo sapiens_hsa005912.51106127
17Selenocompound metabolism_Homo sapiens_hsa004502.35976200
18Huntingtons disease_Homo sapiens_hsa050162.21876669
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.19212533
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18646553
21Nitrogen metabolism_Homo sapiens_hsa009102.15688533
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.00789813
23Tryptophan metabolism_Homo sapiens_hsa003801.96898084
24Olfactory transduction_Homo sapiens_hsa047401.96624414
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.95031908
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.93104251
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.90065138
28Nicotine addiction_Homo sapiens_hsa050331.80279627
29Oocyte meiosis_Homo sapiens_hsa041141.79607186
30Glycerolipid metabolism_Homo sapiens_hsa005611.76319153
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.72762580
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.69998280
33Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.56766645
34PPAR signaling pathway_Homo sapiens_hsa033201.51624295
35Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.50909315
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.50111610
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.48151780
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.46606218
39Amphetamine addiction_Homo sapiens_hsa050311.44944649
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.42375404
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.40826169
42Morphine addiction_Homo sapiens_hsa050321.38675409
43Ether lipid metabolism_Homo sapiens_hsa005651.34969622
44Protein export_Homo sapiens_hsa030601.32594962
45Cardiac muscle contraction_Homo sapiens_hsa042601.29824885
46Circadian entrainment_Homo sapiens_hsa047131.27725604
47Fructose and mannose metabolism_Homo sapiens_hsa000511.24235093
48Regulation of autophagy_Homo sapiens_hsa041401.23258609
49Carbon metabolism_Homo sapiens_hsa012001.18399415
50beta-Alanine metabolism_Homo sapiens_hsa004101.18161943
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.17349757
52Mineral absorption_Homo sapiens_hsa049781.16850545
53Renin secretion_Homo sapiens_hsa049241.15059198
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.13992638
55Fatty acid metabolism_Homo sapiens_hsa012121.13467804
56Glutamatergic synapse_Homo sapiens_hsa047241.13116458
57Cysteine and methionine metabolism_Homo sapiens_hsa002701.13060709
58Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12429189
59mRNA surveillance pathway_Homo sapiens_hsa030151.11237278
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.09599552
61Graft-versus-host disease_Homo sapiens_hsa053321.07295385
62Glycosaminoglycan degradation_Homo sapiens_hsa005311.04560962
63Legionellosis_Homo sapiens_hsa051341.03643875
64Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.01963502
65ABC transporters_Homo sapiens_hsa020101.01879474
66Antigen processing and presentation_Homo sapiens_hsa046121.01004409
67Serotonergic synapse_Homo sapiens_hsa047260.99894503
68Fat digestion and absorption_Homo sapiens_hsa049750.99394970
69GABAergic synapse_Homo sapiens_hsa047270.98606269
70Peroxisome_Homo sapiens_hsa041460.97921594
71Fatty acid degradation_Homo sapiens_hsa000710.92095304
72Purine metabolism_Homo sapiens_hsa002300.91793824
73Circadian rhythm_Homo sapiens_hsa047100.87185469
74RNA transport_Homo sapiens_hsa030130.86481472
75Salmonella infection_Homo sapiens_hsa051320.83161875
76RNA polymerase_Homo sapiens_hsa030200.82750083
77Biosynthesis of amino acids_Homo sapiens_hsa012300.81420230
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.80064657
79Arachidonic acid metabolism_Homo sapiens_hsa005900.79845578
80Caffeine metabolism_Homo sapiens_hsa002320.77962911
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.73424748
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73423718
83Calcium signaling pathway_Homo sapiens_hsa040200.73379982
84Glutathione metabolism_Homo sapiens_hsa004800.72992453
85Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72719939
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.70372857
87Renin-angiotensin system_Homo sapiens_hsa046140.70128575
88Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67764945
89Long-term potentiation_Homo sapiens_hsa047200.66189431
90Chemical carcinogenesis_Homo sapiens_hsa052040.63018904
91Non-homologous end-joining_Homo sapiens_hsa034500.62651003
92Histidine metabolism_Homo sapiens_hsa003400.62099538
93Lysine degradation_Homo sapiens_hsa003100.59359694
94Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57949673
95Estrogen signaling pathway_Homo sapiens_hsa049150.57108346
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57094415
97Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56738489
98Sphingolipid metabolism_Homo sapiens_hsa006000.55697679
99Long-term depression_Homo sapiens_hsa047300.55268035
100Ovarian steroidogenesis_Homo sapiens_hsa049130.55054022
101Dopaminergic synapse_Homo sapiens_hsa047280.54437827
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52701639
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52658711
104Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.52159371
105Endocytosis_Homo sapiens_hsa041440.51151447
106N-Glycan biosynthesis_Homo sapiens_hsa005100.49701909
107Hedgehog signaling pathway_Homo sapiens_hsa043400.48010433
108Arginine and proline metabolism_Homo sapiens_hsa003300.45957032
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.43559394
110Inositol phosphate metabolism_Homo sapiens_hsa005620.43312488
111Type I diabetes mellitus_Homo sapiens_hsa049400.42847929
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41712724
113Retinol metabolism_Homo sapiens_hsa008300.41233481
114Gastric acid secretion_Homo sapiens_hsa049710.40368073
115Cholinergic synapse_Homo sapiens_hsa047250.40354850
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.39699683
117One carbon pool by folate_Homo sapiens_hsa006700.39465270
118Taste transduction_Homo sapiens_hsa047420.39084011
119Homologous recombination_Homo sapiens_hsa034400.38120958
120Aldosterone synthesis and secretion_Homo sapiens_hsa049250.36669835
121Insulin secretion_Homo sapiens_hsa049110.35961267
122Bile secretion_Homo sapiens_hsa049760.35009319
123TGF-beta signaling pathway_Homo sapiens_hsa043500.34978293
124Sulfur metabolism_Homo sapiens_hsa009200.34588096
125cGMP-PKG signaling pathway_Homo sapiens_hsa040220.33347810
126Autoimmune thyroid disease_Homo sapiens_hsa053200.32617007
127Metabolic pathways_Homo sapiens_hsa011000.31358744
128Steroid biosynthesis_Homo sapiens_hsa001000.31357574
129African trypanosomiasis_Homo sapiens_hsa051430.31258965
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31022746
131Rheumatoid arthritis_Homo sapiens_hsa053230.30975360
132Thyroid hormone synthesis_Homo sapiens_hsa049180.30300046
133AMPK signaling pathway_Homo sapiens_hsa041520.30033198
134Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28903688
135Central carbon metabolism in cancer_Homo sapiens_hsa052300.25815714
136Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.25066483
137Pancreatic secretion_Homo sapiens_hsa049720.23178205
138Steroid hormone biosynthesis_Homo sapiens_hsa001400.22317099
139Fatty acid elongation_Homo sapiens_hsa000620.21497997
140Measles_Homo sapiens_hsa051620.19613738
141VEGF signaling pathway_Homo sapiens_hsa043700.18975167
142Protein digestion and absorption_Homo sapiens_hsa049740.18477750
143Influenza A_Homo sapiens_hsa051640.18450447
144Vascular smooth muscle contraction_Homo sapiens_hsa042700.16501404
145Malaria_Homo sapiens_hsa051440.16334767
146RNA degradation_Homo sapiens_hsa030180.15506649
147Collecting duct acid secretion_Homo sapiens_hsa049660.15397980
148cAMP signaling pathway_Homo sapiens_hsa040240.15289615
149Wnt signaling pathway_Homo sapiens_hsa043100.15003084
150Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.14892583
151Cocaine addiction_Homo sapiens_hsa050300.14858169
152Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14366339
153Salivary secretion_Homo sapiens_hsa049700.14103527
154Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.14020358

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