CCDC62

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.59961334
2behavioral response to nicotine (GO:0035095)5.18827020
3piRNA metabolic process (GO:0034587)4.97037767
4DNA deamination (GO:0045006)4.93226626
5cilium or flagellum-dependent cell motility (GO:0001539)4.30085982
6rRNA modification (GO:0000154)4.22310749
7telomere maintenance via semi-conservative replication (GO:0032201)4.20770389
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.18143285
9kinetochore assembly (GO:0051382)4.16813882
10regulation of cilium movement (GO:0003352)4.14774020
11DNA replication checkpoint (GO:0000076)4.14189993
12protein polyglutamylation (GO:0018095)4.11796935
13protein K6-linked ubiquitination (GO:0085020)4.08057957
14DNA methylation involved in gamete generation (GO:0043046)4.05099040
15chromatin remodeling at centromere (GO:0031055)4.02383977
16synaptonemal complex assembly (GO:0007130)3.98428329
17male meiosis (GO:0007140)3.96710722
18mitotic metaphase plate congression (GO:0007080)3.96059955
19telomere maintenance via recombination (GO:0000722)3.95561096
20kinetochore organization (GO:0051383)3.93897049
21CENP-A containing nucleosome assembly (GO:0034080)3.93759879
22termination of RNA polymerase III transcription (GO:0006386)3.89769306
23transcription elongation from RNA polymerase III promoter (GO:0006385)3.89769306
24fucose catabolic process (GO:0019317)3.82533793
25L-fucose metabolic process (GO:0042354)3.82533793
26L-fucose catabolic process (GO:0042355)3.82533793
27platelet dense granule organization (GO:0060155)3.80814030
28proteasome assembly (GO:0043248)3.79312011
29synaptonemal complex organization (GO:0070193)3.77951225
30DNA-dependent DNA replication (GO:0006261)3.73650426
31regulation of nuclear cell cycle DNA replication (GO:0033262)3.70344145
32indole-containing compound catabolic process (GO:0042436)3.69453297
33indolalkylamine catabolic process (GO:0046218)3.69453297
34tryptophan catabolic process (GO:0006569)3.69453297
35DNA strand elongation involved in DNA replication (GO:0006271)3.68311028
36maturation of 5.8S rRNA (GO:0000460)3.65275389
37DNA replication initiation (GO:0006270)3.63586366
38microtubule depolymerization (GO:0007019)3.61904734
39regulation of meiosis I (GO:0060631)3.61862021
40axonemal dynein complex assembly (GO:0070286)3.60210019
41indolalkylamine metabolic process (GO:0006586)3.59916828
42histone exchange (GO:0043486)3.57991031
43mitotic recombination (GO:0006312)3.57575088
447-methylguanosine mRNA capping (GO:0006370)3.56214389
45DNA strand elongation (GO:0022616)3.55865548
46detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.53771963
47deoxyribonucleotide biosynthetic process (GO:0009263)3.53238320
48meiotic chromosome segregation (GO:0045132)3.52660474
49rRNA methylation (GO:0031167)3.51904301
50mitochondrial DNA replication (GO:0006264)3.49962098
517-methylguanosine RNA capping (GO:0009452)3.49696285
52RNA capping (GO:0036260)3.49696285
53water-soluble vitamin biosynthetic process (GO:0042364)3.48528328
54DNA synthesis involved in DNA repair (GO:0000731)3.47649403
55transcription from RNA polymerase I promoter (GO:0006360)3.45833233
56telomere maintenance via telomere lengthening (GO:0010833)3.44951564
57transcription-coupled nucleotide-excision repair (GO:0006283)3.44467340
58deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.44437119
59axoneme assembly (GO:0035082)3.44322667
60termination of RNA polymerase I transcription (GO:0006363)3.43676183
61synapsis (GO:0007129)3.43355762
62ribosome biogenesis (GO:0042254)3.40305156
63binding of sperm to zona pellucida (GO:0007339)3.39003433
64deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.38293895
65metaphase plate congression (GO:0051310)3.37753558
66chromosome organization involved in meiosis (GO:0070192)3.36550101
67sperm-egg recognition (GO:0035036)3.35746551
68cilium movement (GO:0003341)3.35680406
69centriole replication (GO:0007099)3.34140402
70regulation of centriole replication (GO:0046599)3.33752895
71transcription elongation from RNA polymerase I promoter (GO:0006362)3.32597074
72nonmotile primary cilium assembly (GO:0035058)3.32230289
73cellular ketone body metabolic process (GO:0046950)3.31373850
74centriole assembly (GO:0098534)3.31299322
75establishment of protein localization to Golgi (GO:0072600)3.30992880
76negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)3.30694796
77deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.28884400
78spliceosomal snRNP assembly (GO:0000387)3.28389775
79exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.27943169
80DNA replication-independent nucleosome assembly (GO:0006336)3.25534921
81DNA replication-independent nucleosome organization (GO:0034724)3.25534921
82regulation of double-strand break repair via homologous recombination (GO:0010569)3.25446770
83ribosomal large subunit biogenesis (GO:0042273)3.23820297
84acrosome reaction (GO:0007340)3.23733465
85viral mRNA export from host cell nucleus (GO:0046784)3.22432371
86tryptophan metabolic process (GO:0006568)3.20072673
87ribosome assembly (GO:0042255)3.19535749
88meiotic nuclear division (GO:0007126)3.19516779
89nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.17187892
90maturation of SSU-rRNA (GO:0030490)3.16641864
91fusion of sperm to egg plasma membrane (GO:0007342)3.15492367
92ribonucleoprotein complex biogenesis (GO:0022613)3.12696886
93spermatid development (GO:0007286)3.12574041
94pseudouridine synthesis (GO:0001522)3.11953396
95protein targeting to Golgi (GO:0000042)3.10509767
96purine nucleobase biosynthetic process (GO:0009113)3.10133585
97negative regulation of telomere maintenance (GO:0032205)3.09647587
98male meiosis I (GO:0007141)3.08428926
99nucleotide-excision repair, DNA gap filling (GO:0006297)3.06958766
100cell-cell recognition (GO:0009988)3.06683179
101single strand break repair (GO:0000012)3.06370529
102epithelial cilium movement (GO:0003351)3.05862399
103cilium morphogenesis (GO:0060271)3.04328220
104double-strand break repair via homologous recombination (GO:0000724)3.03887032
105recombinational repair (GO:0000725)3.03675085
106nucleobase biosynthetic process (GO:0046112)3.03392950
107transcription initiation from RNA polymerase I promoter (GO:0006361)3.02870859
108cell wall macromolecule catabolic process (GO:0016998)3.01627068
109regulation of microtubule-based movement (GO:0060632)3.01094073
110DNA double-strand break processing (GO:0000729)3.00750268
111rRNA processing (GO:0006364)3.00686676
112spliceosomal complex assembly (GO:0000245)2.99769473
113regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)2.98708904
114ketone body metabolic process (GO:1902224)2.98109515
115meiosis I (GO:0007127)2.97719142
116kynurenine metabolic process (GO:0070189)2.97267547
117multicellular organism reproduction (GO:0032504)2.95812101
118guanosine-containing compound biosynthetic process (GO:1901070)2.95219919
119cilium organization (GO:0044782)2.94844687
120reciprocal meiotic recombination (GO:0007131)2.94698115
121reciprocal DNA recombination (GO:0035825)2.94698115
122GTP biosynthetic process (GO:0006183)2.94677311
123rRNA metabolic process (GO:0016072)2.93898368
124motile cilium assembly (GO:0044458)2.93862053
125establishment of chromosome localization (GO:0051303)2.93731470
126RNA methylation (GO:0001510)2.93336935
127attachment of spindle microtubules to kinetochore (GO:0008608)2.91674030
128protein K11-linked deubiquitination (GO:0035871)2.91439392
129maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.91131116
130mismatch repair (GO:0006298)2.91105899
131transcription elongation from RNA polymerase II promoter (GO:0006368)2.90518469
132negative regulation of DNA-dependent DNA replication (GO:2000104)2.89660267
133regulation of helicase activity (GO:0051095)2.89634128
134sperm motility (GO:0030317)2.89581751
135tRNA methylation (GO:0030488)2.88860801
136histone H2A acetylation (GO:0043968)2.85850203
137meiotic cell cycle process (GO:1903046)2.85156064
138cilium assembly (GO:0042384)2.84856622
139replication fork processing (GO:0031297)2.84641088
140behavioral response to ethanol (GO:0048149)2.81435014
141cell wall macromolecule metabolic process (GO:0044036)2.81121052
142protein localization to cilium (GO:0061512)2.80201271
143retinal cone cell development (GO:0046549)2.79583766
144retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77768024
145protein complex biogenesis (GO:0070271)2.75101418
146negative regulation of transcription regulatory region DNA binding (GO:2000678)2.74654058
147photoreceptor cell maintenance (GO:0045494)2.74255514
148detection of light stimulus involved in visual perception (GO:0050908)2.73942327
149detection of light stimulus involved in sensory perception (GO:0050962)2.73942327
150organic cation transport (GO:0015695)2.72354558
151protein localization to Golgi apparatus (GO:0034067)2.70170716
152intraciliary transport (GO:0042073)2.68304566
153regulation of rhodopsin mediated signaling pathway (GO:0022400)2.67631046
154negative regulation of mast cell activation (GO:0033004)2.64906972
155seminiferous tubule development (GO:0072520)2.64423547
156rhodopsin mediated signaling pathway (GO:0016056)2.63088428
157protein-cofactor linkage (GO:0018065)2.62161563
158regulation of telomere maintenance (GO:0032204)2.60519691
159C4-dicarboxylate transport (GO:0015740)2.60028642
160mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.59294647
161mitochondrial respiratory chain complex I assembly (GO:0032981)2.59294647
162NADH dehydrogenase complex assembly (GO:0010257)2.59294647
163aromatic amino acid family catabolic process (GO:0009074)2.58732744
164cullin deneddylation (GO:0010388)2.58557022
165mannosylation (GO:0097502)2.57179227
166anterograde synaptic vesicle transport (GO:0048490)2.55015539
167mitochondrial respiratory chain complex assembly (GO:0033108)2.53750266
168photoreceptor cell development (GO:0042461)2.52430599
169cellular response to ATP (GO:0071318)2.52156332
170preassembly of GPI anchor in ER membrane (GO:0016254)2.50978128
171somite development (GO:0061053)2.50955463
172indole-containing compound metabolic process (GO:0042430)2.47664338
173cellular biogenic amine catabolic process (GO:0042402)2.46992100
174amine catabolic process (GO:0009310)2.46992100
175auditory receptor cell stereocilium organization (GO:0060088)2.45053598
176proline transport (GO:0015824)2.44636993
177positive regulation of meiosis (GO:0045836)2.43709113

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.67245353
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.53113992
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.11990907
4ZNF274_21170338_ChIP-Seq_K562_Hela3.88073826
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.46841828
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.44901294
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.43539481
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.38616721
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.26108635
10GABP_17652178_ChIP-ChIP_JURKAT_Human3.20393537
11VDR_22108803_ChIP-Seq_LS180_Human3.14031273
12IGF1R_20145208_ChIP-Seq_DFB_Human2.94850809
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.94645826
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.91682873
15GBX2_23144817_ChIP-Seq_PC3_Human2.79734643
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.79065891
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.70291476
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61478923
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.55720877
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.53137760
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.50357409
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.49041464
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.48032266
24POU3F2_20337985_ChIP-ChIP_501MEL_Human2.45584412
25MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42157227
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.40238052
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.39541406
28VDR_23849224_ChIP-Seq_CD4+_Human2.38022234
29TAF15_26573619_Chip-Seq_HEK293_Human2.37426237
30ELF1_17652178_ChIP-ChIP_JURKAT_Human2.32323724
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.31977109
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.28087841
33ZFP57_27257070_Chip-Seq_ESCs_Mouse2.24586074
34CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18315328
35CTBP1_25329375_ChIP-Seq_LNCAP_Human2.13344402
36EZH2_22144423_ChIP-Seq_EOC_Human2.11105122
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.11098985
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.09841842
39EWS_26573619_Chip-Seq_HEK293_Human2.06274471
40FOXP3_21729870_ChIP-Seq_TREG_Human2.00113536
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.99549951
42P300_19829295_ChIP-Seq_ESCs_Human1.98994506
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.94286839
44NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92587538
45ER_23166858_ChIP-Seq_MCF-7_Human1.91392394
46CBP_20019798_ChIP-Seq_JUKART_Human1.88775096
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.88775096
48EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.87400962
49XRN2_22483619_ChIP-Seq_HELA_Human1.86050385
50EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.84498067
51DCP1A_22483619_ChIP-Seq_HELA_Human1.82576693
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79002056
53E2F1_18555785_ChIP-Seq_MESCs_Mouse1.76297863
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73635918
55TP63_19390658_ChIP-ChIP_HaCaT_Human1.73318661
56THAP11_20581084_ChIP-Seq_MESCs_Mouse1.72215435
57ELK1_19687146_ChIP-ChIP_HELA_Human1.71831135
58TTF2_22483619_ChIP-Seq_HELA_Human1.70754177
59GABP_19822575_ChIP-Seq_HepG2_Human1.67918817
60TP53_22573176_ChIP-Seq_HFKS_Human1.67714650
61* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67224329
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.66043723
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.62603966
64TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62463153
65YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61671751
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61567001
67ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60471176
68BCAT_22108803_ChIP-Seq_LS180_Human1.60163053
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.59640428
70STAT3_23295773_ChIP-Seq_U87_Human1.56124693
71SMAD4_21799915_ChIP-Seq_A2780_Human1.52991648
72E2F1_21310950_ChIP-Seq_MCF-7_Human1.50190734
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.46838868
74SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46069010
75TCF4_23295773_ChIP-Seq_U87_Human1.45462066
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44113449
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43412701
78POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.42496015
79NOTCH1_21737748_ChIP-Seq_TLL_Human1.42370648
80KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.41519991
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41215050
82POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.41215050
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.40295051
84AR_25329375_ChIP-Seq_VCAP_Human1.38284059
85SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.37276390
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.36357802
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35103005
88SOX2_19829295_ChIP-Seq_ESCs_Human1.34437194
89NANOG_19829295_ChIP-Seq_ESCs_Human1.34437194
90PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32984762
91KAP1_22055183_ChIP-Seq_ESCs_Mouse1.32815846
92TCF4_22108803_ChIP-Seq_LS180_Human1.31462927
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.31347883
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.30958474
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29493305
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.29039988
97GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28944531
98MYC_18940864_ChIP-ChIP_HL60_Human1.27595333
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.25964837
100SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.25019851
101FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24239532
102RUNX2_22187159_ChIP-Seq_PCA_Human1.23646455
103AUTS2_25519132_ChIP-Seq_293T-REX_Human1.23544856
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.23438847
105NCOR_22424771_ChIP-Seq_293T_Human1.22883453
106HOXB4_20404135_ChIP-ChIP_EML_Mouse1.21460265
107FOXA1_27270436_Chip-Seq_PROSTATE_Human1.20348379
108FOXA1_25329375_ChIP-Seq_VCAP_Human1.20348379
109TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20265859
110GATA3_21878914_ChIP-Seq_MCF-7_Human1.20093065
111HOXB7_26014856_ChIP-Seq_BT474_Human1.19859334
112SMAD4_21741376_ChIP-Seq_EPCs_Human1.19326584
113FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18647091
114RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18593309
115SOX2_18555785_ChIP-Seq_MESCs_Mouse1.18370684
116AR_21909140_ChIP-Seq_LNCAP_Human1.18229638
117PIAS1_25552417_ChIP-Seq_VCAP_Human1.18221548
118BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17601623
119ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17177833
120PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.15244503
121AR_20517297_ChIP-Seq_VCAP_Human1.14963598
122REST_21632747_ChIP-Seq_MESCs_Mouse1.12969837
123FLI1_21867929_ChIP-Seq_TH2_Mouse1.10189647
124NFE2_27457419_Chip-Seq_LIVER_Mouse1.10173400
125EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09282267
126PRDM14_20953172_ChIP-Seq_ESCs_Human1.08829118
127CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.06328962
128AR_21572438_ChIP-Seq_LNCaP_Human1.06280308
129HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06031079
130MYC_19829295_ChIP-Seq_ESCs_Human1.05878490
131BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.05178196
132NANOG_18555785_Chip-Seq_ESCs_Mouse1.05102161
133CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04287209
134CBX2_27304074_Chip-Seq_ESCs_Mouse1.04088121
135IRF1_19129219_ChIP-ChIP_H3396_Human1.03840254
136CRX_20693478_ChIP-Seq_RETINA_Mouse1.03833474
137SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03786181
138KDM5A_27292631_Chip-Seq_BREAST_Human1.01881951
139EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99904703
140SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99636368
141CIITA_25753668_ChIP-Seq_RAJI_Human0.99489542
142RNF2_27304074_Chip-Seq_NSC_Mouse0.99322340
143ERA_21632823_ChIP-Seq_H3396_Human0.98332294
144TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97812187
145ETV1_20927104_ChIP-Seq_GIST48_Human0.97375002
146PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96968831
147P53_22387025_ChIP-Seq_ESCs_Mouse0.96896827
148OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96594230
149SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96433330
150TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95529057
151NANOG_20526341_ChIP-Seq_ESCs_Human0.95440758
152DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94480971
153* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92126277
154PCGF2_27294783_Chip-Seq_NPCs_Mouse0.91989405
155TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.91234827
156NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.91095849
157SALL1_21062744_ChIP-ChIP_HESCs_Human0.90296056
158KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.89951447
159KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.89951447
160KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.89951447
161ERG_20887958_ChIP-Seq_HPC-7_Mouse0.87319302
162BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86685704
163RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86127367
164ZFX_18555785_ChIP-Seq_MESCs_Mouse0.85780230
165SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.84912211
166GATA1_26923725_Chip-Seq_HPCs_Mouse0.84349472
167E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.80832357
168ELK1_22589737_ChIP-Seq_MCF10A_Human0.80771012
169CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.80402082
170KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.78122991
171SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.75575133
172CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.74794645
173FUS_26573619_Chip-Seq_HEK293_Human0.74481251
174RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.72385943
175SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.71514700
176GATA3_21867929_ChIP-Seq_CD8_Mouse0.69823887
177YY1_22570637_ChIP-Seq_MALME-3M_Human0.66801470
178STAT3_18555785_Chip-Seq_ESCs_Mouse0.66321258

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation4.85078459
2MP0003693_abnormal_embryo_hatching4.55324149
3MP0008058_abnormal_DNA_repair4.10300221
4MP0003111_abnormal_nucleus_morphology3.84417142
5MP0010094_abnormal_chromosome_stability3.78722001
6MP0008057_abnormal_DNA_replication3.52952838
7MP0005410_abnormal_fertilization3.44945135
8MP0006292_abnormal_olfactory_placode3.39561557
9MP0002837_dystrophic_cardiac_calcinosis3.17540422
10MP0003077_abnormal_cell_cycle3.03302091
11MP0000569_abnormal_digit_pigmentation2.94363806
12MP0003786_premature_aging2.78648490
13MP0004957_abnormal_blastocyst_morpholog2.64092351
14MP0003718_maternal_effect2.63665338
15MP0008007_abnormal_cellular_replicative2.61316768
16MP0002210_abnormal_sex_determination2.56174523
17MP0001929_abnormal_gametogenesis2.53029791
18MP0005551_abnormal_eye_electrophysiolog2.42399621
19MP0002160_abnormal_reproductive_system2.25215918
20MP0003698_abnormal_male_reproductive2.20520190
21MP0008932_abnormal_embryonic_tissue2.20242285
22MP0001968_abnormal_touch/_nociception2.13507193
23MP0006072_abnormal_retinal_apoptosis2.05402969
24MP0001145_abnormal_male_reproductive2.03684862
25MP0005645_abnormal_hypothalamus_physiol1.99372418
26MP0001188_hyperpigmentation1.95924734
27MP0003195_calcinosis1.95259793
28MP0008995_early_reproductive_senescence1.93957895
29MP0005646_abnormal_pituitary_gland1.91325879
30MP0000653_abnormal_sex_gland1.88349621
31MP0000566_synostosis1.88124498
32MP0005084_abnormal_gallbladder_morpholo1.83700773
33MP0001984_abnormal_olfaction1.80507873
34MP0005253_abnormal_eye_physiology1.78165052
35MP0004142_abnormal_muscle_tone1.74109374
36MP0009046_muscle_twitch1.73881498
37MP0005389_reproductive_system_phenotype1.73257221
38MP0002277_abnormal_respiratory_mucosa1.70877551
39MP0000427_abnormal_hair_cycle1.66705124
40MP0003315_abnormal_perineum_morphology1.65495533
41MP0003136_yellow_coat_color1.64714867
42MP0008872_abnormal_physiological_respon1.62964352
43MP0004885_abnormal_endolymph1.58871107
44MP0003890_abnormal_embryonic-extraembry1.58438323
45MP0002272_abnormal_nervous_system1.56514331
46MP0009745_abnormal_behavioral_response1.55433652
47MP0008875_abnormal_xenobiotic_pharmacok1.54789340
48MP0003123_paternal_imprinting1.54356491
49MP0002132_abnormal_respiratory_system1.54097684
50MP0001485_abnormal_pinna_reflex1.49222829
51MP0002234_abnormal_pharynx_morphology1.47829130
52MP0006276_abnormal_autonomic_nervous1.46874816
53MP0001501_abnormal_sleep_pattern1.42573459
54MP0002736_abnormal_nociception_after1.41754667
55MP0009697_abnormal_copulation1.40601894
56MP0001119_abnormal_female_reproductive1.40314967
57MP0000015_abnormal_ear_pigmentation1.40182644
58MP0001986_abnormal_taste_sensitivity1.40158649
59MP0002653_abnormal_ependyma_morphology1.37546082
60MP0004043_abnormal_pH_regulation1.37328436
61MP0004147_increased_porphyrin_level1.33021852
62MP0002102_abnormal_ear_morphology1.30881377
63MP0005075_abnormal_melanosome_morpholog1.28850602
64MP0001486_abnormal_startle_reflex1.28177692
65MP0003941_abnormal_skin_development1.27761453
66MP0001919_abnormal_reproductive_system1.27175100
67MP0002161_abnormal_fertility/fecundity1.25992120
68MP0000631_abnormal_neuroendocrine_gland1.25687956
69MP0010030_abnormal_orbit_morphology1.21200744
70MP0004133_heterotaxia1.17929424
71MP0000350_abnormal_cell_proliferation1.17294833
72MP0002735_abnormal_chemical_nociception1.14539063
73MP0005377_hearing/vestibular/ear_phenot1.14345718
74MP0003878_abnormal_ear_physiology1.14345718
75MP0003880_abnormal_central_pattern1.14331458
76MP0000313_abnormal_cell_death1.13961505
77MP0005171_absent_coat_pigmentation1.12856570
78MP0003011_delayed_dark_adaptation1.12226209
79MP0008789_abnormal_olfactory_epithelium1.09128079
80MP0005379_endocrine/exocrine_gland_phen1.08459279
81MP0001970_abnormal_pain_threshold1.07463506
82MP0003186_abnormal_redox_activity1.06800062
83MP0002396_abnormal_hematopoietic_system1.06465897
84MP0005670_abnormal_white_adipose1.06385168
85MP0005174_abnormal_tail_pigmentation1.02559420
86MP0002557_abnormal_social/conspecific_i1.02093677
87MP0003121_genomic_imprinting1.01845038
88MP0004215_abnormal_myocardial_fiber1.01700872
89MP0002163_abnormal_gland_morphology1.01249077
90MP0004742_abnormal_vestibular_system1.00050631
91MP0003787_abnormal_imprinting0.99414840
92MP0000383_abnormal_hair_follicle0.98947337
93MP0004145_abnormal_muscle_electrophysio0.98894632
94MP0002733_abnormal_thermal_nociception0.97770424
95MP0002928_abnormal_bile_duct0.96976405
96MP0010386_abnormal_urinary_bladder0.95242539
97MP0002572_abnormal_emotion/affect_behav0.95226963
98MP0000490_abnormal_crypts_of0.94684003
99MP0002638_abnormal_pupillary_reflex0.94061956
100MP0001293_anophthalmia0.93552950
101MP0005195_abnormal_posterior_eye0.92785988
102MP0001502_abnormal_circadian_rhythm0.92747610
103MP0005395_other_phenotype0.91229427
104MP0001905_abnormal_dopamine_level0.90637057
105MP0005423_abnormal_somatic_nervous0.89705398
106MP0001730_embryonic_growth_arrest0.89275171
107MP0002734_abnormal_mechanical_nocicepti0.88852341
108MP0001186_pigmentation_phenotype0.88450681
109MP0005380_embryogenesis_phenotype0.87768331
110MP0001672_abnormal_embryogenesis/_devel0.87768331
111MP0002064_seizures0.87229559
112MP0005499_abnormal_olfactory_system0.85644062
113MP0005394_taste/olfaction_phenotype0.85644062
114MP0000372_irregular_coat_pigmentation0.85304163
115MP0000613_abnormal_salivary_gland0.84999717
116MP0000049_abnormal_middle_ear0.84519758
117MP0000678_abnormal_parathyroid_gland0.84204741
118MP0002938_white_spotting0.81837394
119MP0000026_abnormal_inner_ear0.81002726
120MP0002095_abnormal_skin_pigmentation0.80952134
121MP0003635_abnormal_synaptic_transmissio0.80259906
122MP0005391_vision/eye_phenotype0.79675486
123MP0002752_abnormal_somatic_nervous0.78580483
124MP0002229_neurodegeneration0.77978356
125MP0002067_abnormal_sensory_capabilities0.77939617
126MP0001853_heart_inflammation0.77536457
127MP0000230_abnormal_systemic_arterial0.77351629
128MP0008260_abnormal_autophagy0.77256765
129MP0005360_urolithiasis0.77127186
130MP0002019_abnormal_tumor_incidence0.77121190
131MP0002254_reproductive_system_inflammat0.76649495
132MP0003699_abnormal_female_reproductive0.76173566
133MP0005408_hypopigmentation0.75796933
134MP0001529_abnormal_vocalization0.75369151
135MP0002085_abnormal_embryonic_tissue0.74354048
136MP0005310_abnormal_salivary_gland0.74050827
137MP0009333_abnormal_splenocyte_physiolog0.73923260
138MP0004381_abnormal_hair_follicle0.73805922
139MP0001963_abnormal_hearing_physiology0.73398038
140MP0003936_abnormal_reproductive_system0.73201063
141MP0001697_abnormal_embryo_size0.72464464
142MP0010307_abnormal_tumor_latency0.70633279
143MP0001286_abnormal_eye_development0.70505245
144MP0004808_abnormal_hematopoietic_stem0.69147830
145MP0002075_abnormal_coat/hair_pigmentati0.67836546
146MP0001764_abnormal_homeostasis0.67808735
147MP0003763_abnormal_thymus_physiology0.67192666
148MP0003937_abnormal_limbs/digits/tail_de0.67059785
149MP0002751_abnormal_autonomic_nervous0.63929828
150MP0005647_abnormal_sex_gland0.62371179
151MP0002080_prenatal_lethality0.60905075
152MP0006035_abnormal_mitochondrial_morpho0.60809589
153MP0009379_abnormal_foot_pigmentation0.60482661
154MP0003984_embryonic_growth_retardation0.58744492
155MP0000703_abnormal_thymus_morphology0.57472821
156MP0002876_abnormal_thyroid_physiology0.57014525
157MP0004782_abnormal_surfactant_physiolog0.56844009
158MP0002088_abnormal_embryonic_growth/wei0.55084499
159MP0003646_muscle_fatigue0.53657312
160MP0005409_darkened_coat_color0.53320183

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.31629292
2Chromsome breakage (HP:0040012)5.12860729
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.81596162
4Dynein arm defect of respiratory motile cilia (HP:0012255)4.33744343
5Absent/shortened dynein arms (HP:0200106)4.33744343
6Birth length less than 3rd percentile (HP:0003561)3.95267441
7Congenital stationary night blindness (HP:0007642)3.80656540
8Abnormal respiratory motile cilium morphology (HP:0005938)3.73796884
9Abnormal respiratory epithelium morphology (HP:0012253)3.73796884
10Attenuation of retinal blood vessels (HP:0007843)3.59710592
11Meckel diverticulum (HP:0002245)3.56502875
12Breast hypoplasia (HP:0003187)3.53173766
13Abnormal respiratory motile cilium physiology (HP:0012261)3.52514803
14Abnormality of the preputium (HP:0100587)3.44512304
15Type II lissencephaly (HP:0007260)3.42914328
16Chronic hepatic failure (HP:0100626)3.39513568
17Abnormality of the ileum (HP:0001549)3.38932743
18Progressive external ophthalmoplegia (HP:0000590)3.30362537
19Aplasia/Hypoplasia of the uvula (HP:0010293)3.25835274
20Abnormal ciliary motility (HP:0012262)3.24444406
21Abnormal spermatogenesis (HP:0008669)3.18488163
22Abnormality of chromosome stability (HP:0003220)3.14613655
23Abnormality of the renal cortex (HP:0011035)3.14195930
24Impulsivity (HP:0100710)3.11330197
25Supernumerary spleens (HP:0009799)3.01699046
26Reticulocytopenia (HP:0001896)2.94064384
27Duplicated collecting system (HP:0000081)2.92638742
28Ectopic kidney (HP:0000086)2.84991304
29Cerebellar dysplasia (HP:0007033)2.82757373
30Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.80422337
31Azoospermia (HP:0000027)2.79371872
32Chronic bronchitis (HP:0004469)2.77024603
33Bony spicule pigmentary retinopathy (HP:0007737)2.75565229
34Carpal bone hypoplasia (HP:0001498)2.75484080
35Abnormal rod and cone electroretinograms (HP:0008323)2.74653573
36Tubular atrophy (HP:0000092)2.74368899
37Cystic liver disease (HP:0006706)2.72531961
38Pancreatic fibrosis (HP:0100732)2.70636203
39Polydipsia (HP:0001959)2.66909523
40Abnormal drinking behavior (HP:0030082)2.66909523
41Pancreatic cysts (HP:0001737)2.66340944
42Pendular nystagmus (HP:0012043)2.65507958
43Patellar aplasia (HP:0006443)2.65412694
44Abnormality of the renal collecting system (HP:0004742)2.65056051
45Rhinitis (HP:0012384)2.64470300
46Absent radius (HP:0003974)2.62363348
47Type I transferrin isoform profile (HP:0003642)2.58824346
48Absent thumb (HP:0009777)2.54053253
49Aplasia/Hypoplasia of the patella (HP:0006498)2.53813026
50Duodenal stenosis (HP:0100867)2.53794947
51Small intestinal stenosis (HP:0012848)2.53794947
52Facial cleft (HP:0002006)2.52966563
53Abolished electroretinogram (ERG) (HP:0000550)2.50978453
54Type 2 muscle fiber atrophy (HP:0003554)2.49879850
55Absent forearm bone (HP:0003953)2.47163996
56Aplasia involving forearm bones (HP:0009822)2.47163996
57Neonatal respiratory distress (HP:0002643)2.43575860
58Clubbing of toes (HP:0100760)2.43121128
59Volvulus (HP:0002580)2.42255085
60Nephronophthisis (HP:0000090)2.42001698
61True hermaphroditism (HP:0010459)2.41950429
62Bone marrow hypocellularity (HP:0005528)2.40395127
63Triphalangeal thumb (HP:0001199)2.38153691
64Abnormality of the anterior horn cell (HP:0006802)2.37016998
65Degeneration of anterior horn cells (HP:0002398)2.37016998
66Horseshoe kidney (HP:0000085)2.34716756
67Aplastic anemia (HP:0001915)2.32059068
68Microvesicular hepatic steatosis (HP:0001414)2.29805426
69Progressive inability to walk (HP:0002505)2.28691132
70Lissencephaly (HP:0001339)2.28426717
71Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.27471698
72Colon cancer (HP:0003003)2.26350439
73Abnormal lung lobation (HP:0002101)2.26238278
74Rough bone trabeculation (HP:0100670)2.26149139
75Congenital primary aphakia (HP:0007707)2.25436113
76Tubulointerstitial nephritis (HP:0001970)2.25203683
77Gait imbalance (HP:0002141)2.24040039
78Aplasia/Hypoplasia of the tongue (HP:0010295)2.22897691
793-Methylglutaconic aciduria (HP:0003535)2.21897535
80Polyuria (HP:0000103)2.20476247
8111 pairs of ribs (HP:0000878)2.19763288
82Sloping forehead (HP:0000340)2.19656443
83Median cleft lip (HP:0000161)2.18762381
84Abnormality of macular pigmentation (HP:0008002)2.17404466
85Progressive cerebellar ataxia (HP:0002073)2.16128426
86Aplasia/Hypoplasia of the tibia (HP:0005772)2.14373447
87Nephrogenic diabetes insipidus (HP:0009806)2.13062440
88Muscle fiber atrophy (HP:0100295)2.12114513
89Inability to walk (HP:0002540)2.10496723
90Aplasia/Hypoplasia involving the musculature (HP:0001460)2.10204591
91Myelodysplasia (HP:0002863)2.10162699
92Gaze-evoked nystagmus (HP:0000640)2.09577709
93Sclerocornea (HP:0000647)2.08945578
94Selective tooth agenesis (HP:0001592)2.08593110
95Abnormality of the duodenum (HP:0002246)2.06370381
96Renal cortical cysts (HP:0000803)2.06358881
97Oral leukoplakia (HP:0002745)2.06298703
98Short thumb (HP:0009778)2.06011386
99Congenital sensorineural hearing impairment (HP:0008527)2.05999138
100Anencephaly (HP:0002323)2.05859431
101Molar tooth sign on MRI (HP:0002419)2.03180193
102Abnormality of midbrain morphology (HP:0002418)2.03180193
103Abnormality of the labia minora (HP:0012880)2.03007159
104Increased CSF lactate (HP:0002490)2.01474230
105Cleft eyelid (HP:0000625)2.01419777
106Nephroblastoma (Wilms tumor) (HP:0002667)2.01266240
107Abnormality of the carotid arteries (HP:0005344)2.00751627
108Hyperventilation (HP:0002883)1.99660710
109Medial flaring of the eyebrow (HP:0010747)1.98240534
110Postaxial foot polydactyly (HP:0001830)1.97666983
111Abnormal biliary tract physiology (HP:0012439)1.96894635
112Bile duct proliferation (HP:0001408)1.96894635
113Preaxial hand polydactyly (HP:0001177)1.96860008
114Hypoplasia of the radius (HP:0002984)1.96080818
115Decreased central vision (HP:0007663)1.96017256
116Proximal tubulopathy (HP:0000114)1.95288742
117Aplasia/hypoplasia of the uterus (HP:0008684)1.95145756
118Congenital hepatic fibrosis (HP:0002612)1.95045294
119Pancytopenia (HP:0001876)1.94047612
120External ophthalmoplegia (HP:0000544)1.93516458
121Mitochondrial inheritance (HP:0001427)1.93277063
122Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.92136669
123Abnormality of alanine metabolism (HP:0010916)1.92136669
124Hyperalaninemia (HP:0003348)1.92136669
125Premature graying of hair (HP:0002216)1.91671892
126Abnormality of the renal medulla (HP:0100957)1.91183169
127Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90468413
128Aplasia/Hypoplasia of the earlobes (HP:0009906)1.90309329
129Optic nerve hypoplasia (HP:0000609)1.90230572
130Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89218183
131Stomach cancer (HP:0012126)1.88596732
132Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88495443
133Furrowed tongue (HP:0000221)1.87829447
134Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.87755610
135Abnormal number of erythroid precursors (HP:0012131)1.86882167
136Male pseudohermaphroditism (HP:0000037)1.85933746
137Genital tract atresia (HP:0001827)1.85578512
138Acute necrotizing encephalopathy (HP:0006965)1.83540375
139Intestinal atresia (HP:0011100)1.83482453
140Embryonal renal neoplasm (HP:0011794)1.83174625
141Decreased electroretinogram (ERG) amplitude (HP:0000654)1.82789866
142Acute encephalopathy (HP:0006846)1.82741641
143Pachygyria (HP:0001302)1.82122173
144Febrile seizures (HP:0002373)1.81370806
145Abnormality of cells of the erythroid lineage (HP:0012130)1.79945886
146Hypergonadotropic hypogonadism (HP:0000815)1.79739264
147Optic nerve coloboma (HP:0000588)1.79665141
148Abnormality of DNA repair (HP:0003254)1.77939164
149Infertility (HP:0000789)1.77553472
150Bronchiectasis (HP:0002110)1.77442215
151Optic disc pallor (HP:0000543)1.76284001
152Abnormal urine output (HP:0012590)1.76223766
153Tracheoesophageal fistula (HP:0002575)1.75534069
154Prostate neoplasm (HP:0100787)1.75349856
155Oligodactyly (hands) (HP:0001180)1.73893778
156Abnormal trabecular bone morphology (HP:0100671)1.73871650
157Vaginal atresia (HP:0000148)1.73852863
158Tubulointerstitial abnormality (HP:0001969)1.73173933
159Focal motor seizures (HP:0011153)1.72079089
160Methylmalonic acidemia (HP:0002912)1.71621169
161Progressive macrocephaly (HP:0004481)1.71158972
162Aganglionic megacolon (HP:0002251)1.71149786
163Lipid accumulation in hepatocytes (HP:0006561)1.71099732
164Severe muscular hypotonia (HP:0006829)1.70946927
165Increased serum lactate (HP:0002151)1.70489394
166Large for gestational age (HP:0001520)1.69349751
167Increased corneal curvature (HP:0100692)1.69278361
168Keratoconus (HP:0000563)1.69278361
169Astigmatism (HP:0000483)1.69183966
170Hemiparesis (HP:0001269)1.69127027
171Cerebral hypomyelination (HP:0006808)1.68715631
172Poor coordination (HP:0002370)1.67629050
173Aplasia/Hypoplasia of the spleen (HP:0010451)1.67624660
174Chorioretinal atrophy (HP:0000533)1.67398467
175Severe visual impairment (HP:0001141)1.67318363
176Rectal fistula (HP:0100590)1.66940894

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.79428848
2PLK44.74198008
3IRAK34.38601453
4BUB13.63770063
5ZAK3.24381973
6SRPK13.21652951
7STK163.10542266
8WEE12.91267323
9EIF2AK12.84793061
10WNK42.50098449
11MAP4K22.47597984
12CDC72.41511988
13IRAK42.28834806
14TTK2.16581142
15TAOK32.06795884
16INSRR1.99599717
17MAP3K41.97447012
18PINK11.97199972
19MKNK21.90049160
20VRK11.88054470
21TLK11.77070184
22STK38L1.76555813
23IRAK11.73497055
24PLK11.71840790
25EIF2AK31.71154421
26STK391.70840816
27OXSR11.67330689
28IRAK21.60042821
29MKNK11.56072348
30BRSK21.55074654
31AKT31.53507432
32PDK41.53069490
33PDK31.53069490
34PLK21.48653739
35PLK31.48203508
36ATR1.44829274
37EIF2AK21.44015693
38CCNB11.36132917
39PDK21.29890102
40CHEK21.29014100
41EPHA21.28117001
42CDK191.28048974
43NEK21.24265753
44ACVR1B1.23903131
45TAF11.22780580
46TSSK61.15603571
47TNIK1.14185911
48BRD41.13733318
49NEK61.07475218
50DYRK31.07227420
51CDK71.05666532
52TRIM281.05528878
53DAPK21.02498122
54AURKB1.02451397
55PAK30.97645720
56BRAF0.97438930
57YES10.96355908
58TESK10.96297108
59TGFBR10.94322693
60CSNK1G20.92494143
61PRKCE0.92347556
62PTK2B0.91540615
63ADRBK10.91089970
64BRSK10.89637752
65CSNK1G10.86964778
66AURKA0.86677930
67CHEK10.86595057
68BMPR20.83400203
69MARK10.82718188
70NME10.82693050
71CDK30.81903325
72PBK0.80448697
73ATM0.77009827
74PRKCG0.75110359
75STK40.74544846
76CSNK1G30.74496707
77MARK30.73529217
78TXK0.72733437
79PNCK0.69737373
80PIK3CG0.69050070
81BCKDK0.67688279
82CDK80.67460737
83MUSK0.67151441
84RPS6KB20.66254275
85PRKCI0.65626226
86CASK0.63537745
87CSNK1A1L0.62464791
88CSNK2A10.61815153
89GRK10.60914406
90BMPR1B0.60444948
91ADRBK20.60304275
92PRKCQ0.60249296
93DYRK20.57513580
94NLK0.57420606
95NEK10.57189976
96MAPK150.55454155
97CDK120.54622545
98PASK0.54370816
99PIM10.53576795
100CAMK2A0.53320044
101MAPKAPK30.53142412
102EPHA40.50924859
103CDK20.50479715
104TIE10.49688030
105BCR0.47089055
106PRPF4B0.47074865
107CAMK10.46998374
108NTRK30.46975302
109FGFR20.46971363
110FER0.46610764
111RPS6KA40.45855988
112FLT30.44953182
113OBSCN0.44850498
114TEC0.44746188
115IKBKB0.44632582
116CSNK2A20.43811901
117SIK30.42868917
118PRKD30.42288534
119NUAK10.42271146
120NME20.42017593
121PIM20.41999187
122PRKACA0.41716429
123RPS6KA50.41415473
124CSNK1A10.41371330
125PRKACB0.40901191
126PKN10.40624821
127STK30.40435584
128PHKG20.40200302
129PHKG10.40200302
130CDK10.40006455
131TNK20.39658302
132CSNK1D0.38867334
133STK110.38316691
134PRKG10.36956264
135TESK20.36462830
136SGK20.36380774
137WNK10.35352025
138MAP2K60.34286337
139CAMKK20.32290031
140CLK10.31947908
141MAPK130.31700728
142MAP3K140.31440051
143LATS20.29708577
144MAPK70.28251412
145CDK40.27110036
146WNK30.27010701
147TAOK20.26154147
148LATS10.24492431
149MAP2K70.24266419
150ERBB30.23431746
151PAK10.23350855
152MAP3K80.22980172
153ABL20.21935066

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.25653544
2RNA polymerase_Homo sapiens_hsa030204.15409455
3Mismatch repair_Homo sapiens_hsa034303.87147120
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.65093780
5Fanconi anemia pathway_Homo sapiens_hsa034603.52435797
6Homologous recombination_Homo sapiens_hsa034403.45726849
7Proteasome_Homo sapiens_hsa030503.28209363
8Pyrimidine metabolism_Homo sapiens_hsa002403.02652946
9Spliceosome_Homo sapiens_hsa030402.92556931
10Ribosome_Homo sapiens_hsa030102.92086369
11Basal transcription factors_Homo sapiens_hsa030222.73307133
12Base excision repair_Homo sapiens_hsa034102.71808619
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.63324104
14Nucleotide excision repair_Homo sapiens_hsa034202.61911565
15RNA transport_Homo sapiens_hsa030132.55900281
16Butanoate metabolism_Homo sapiens_hsa006502.24050335
17Cell cycle_Homo sapiens_hsa041102.14120795
18RNA degradation_Homo sapiens_hsa030182.13183153
19Nitrogen metabolism_Homo sapiens_hsa009102.12020246
20Nicotine addiction_Homo sapiens_hsa050332.11019432
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.03677811
22Purine metabolism_Homo sapiens_hsa002302.01795017
23Non-homologous end-joining_Homo sapiens_hsa034502.01485213
24One carbon pool by folate_Homo sapiens_hsa006701.96184195
25Vitamin B6 metabolism_Homo sapiens_hsa007501.86001511
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.84272050
27Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.81845018
28Olfactory transduction_Homo sapiens_hsa047401.78184989
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64357356
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.62576772
31Taste transduction_Homo sapiens_hsa047421.60864529
32Tryptophan metabolism_Homo sapiens_hsa003801.59373073
33Caffeine metabolism_Homo sapiens_hsa002321.58272533
34Propanoate metabolism_Homo sapiens_hsa006401.53991951
35p53 signaling pathway_Homo sapiens_hsa041151.53807973
36Huntingtons disease_Homo sapiens_hsa050161.53248764
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.48197164
38mRNA surveillance pathway_Homo sapiens_hsa030151.41286298
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.40996592
40Morphine addiction_Homo sapiens_hsa050321.30623383
41Oxidative phosphorylation_Homo sapiens_hsa001901.23990323
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.16349866
43Protein export_Homo sapiens_hsa030601.11821865
44Parkinsons disease_Homo sapiens_hsa050121.06481383
45Epstein-Barr virus infection_Homo sapiens_hsa051691.05212143
46Cardiac muscle contraction_Homo sapiens_hsa042601.03229522
47Arachidonic acid metabolism_Homo sapiens_hsa005901.00669936
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.98431929
49ABC transporters_Homo sapiens_hsa020100.96974838
50Chemical carcinogenesis_Homo sapiens_hsa052040.91861129
51Circadian entrainment_Homo sapiens_hsa047130.89670533
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.88246109
53GABAergic synapse_Homo sapiens_hsa047270.87309801
54Fatty acid biosynthesis_Homo sapiens_hsa000610.86821368
55Dorso-ventral axis formation_Homo sapiens_hsa043200.86761483
56Insulin secretion_Homo sapiens_hsa049110.86525473
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.84646607
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.83924939
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.83743327
60Peroxisome_Homo sapiens_hsa041460.80778995
61Linoleic acid metabolism_Homo sapiens_hsa005910.80141992
62Glutathione metabolism_Homo sapiens_hsa004800.79664168
63Herpes simplex infection_Homo sapiens_hsa051680.79014729
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.78726913
65Collecting duct acid secretion_Homo sapiens_hsa049660.77899697
66Serotonergic synapse_Homo sapiens_hsa047260.74458843
67Salivary secretion_Homo sapiens_hsa049700.73302773
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73108836
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72431572
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71939708
71Glutamatergic synapse_Homo sapiens_hsa047240.71908836
72Systemic lupus erythematosus_Homo sapiens_hsa053220.71056991
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.67115569
74Fatty acid elongation_Homo sapiens_hsa000620.66845817
75Calcium signaling pathway_Homo sapiens_hsa040200.66840137
76Oocyte meiosis_Homo sapiens_hsa041140.66040651
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64562436
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63847417
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.63496495
80Ovarian steroidogenesis_Homo sapiens_hsa049130.63300628
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61565104
82Glycerolipid metabolism_Homo sapiens_hsa005610.60697578
83Type I diabetes mellitus_Homo sapiens_hsa049400.59997772
84Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59682140
85Folate biosynthesis_Homo sapiens_hsa007900.58728224
86Pentose phosphate pathway_Homo sapiens_hsa000300.58385840
87Metabolic pathways_Homo sapiens_hsa011000.56579761
88Sphingolipid metabolism_Homo sapiens_hsa006000.54234952
89Selenocompound metabolism_Homo sapiens_hsa004500.53347832
90Alzheimers disease_Homo sapiens_hsa050100.51099961
91Autoimmune thyroid disease_Homo sapiens_hsa053200.50872586
92NF-kappa B signaling pathway_Homo sapiens_hsa040640.49405731
93Phototransduction_Homo sapiens_hsa047440.49380175
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48851609
95Fructose and mannose metabolism_Homo sapiens_hsa000510.45877899
96Graft-versus-host disease_Homo sapiens_hsa053320.44642241
97Other glycan degradation_Homo sapiens_hsa005110.44455162
98Ether lipid metabolism_Homo sapiens_hsa005650.43135712
99beta-Alanine metabolism_Homo sapiens_hsa004100.43079433
100Hedgehog signaling pathway_Homo sapiens_hsa043400.41512456
101Regulation of autophagy_Homo sapiens_hsa041400.41172613
102Intestinal immune network for IgA production_Homo sapiens_hsa046720.40184748
103Fat digestion and absorption_Homo sapiens_hsa049750.39937962
104Allograft rejection_Homo sapiens_hsa053300.39567464
105Mineral absorption_Homo sapiens_hsa049780.37955308
106Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37702875
107HTLV-I infection_Homo sapiens_hsa051660.35671344
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35039143
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35013625
110Measles_Homo sapiens_hsa051620.34360818
111cAMP signaling pathway_Homo sapiens_hsa040240.33522093
112Viral carcinogenesis_Homo sapiens_hsa052030.33040076
113Long-term depression_Homo sapiens_hsa047300.32868416
114Antigen processing and presentation_Homo sapiens_hsa046120.32852689
115Vitamin digestion and absorption_Homo sapiens_hsa049770.31665156
116RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.29641616
117Primary immunodeficiency_Homo sapiens_hsa053400.28945408
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.26465104
119Fatty acid metabolism_Homo sapiens_hsa012120.26041947
120Influenza A_Homo sapiens_hsa051640.25271583
121Legionellosis_Homo sapiens_hsa051340.24376723
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.24095756
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.23438752
124Sulfur relay system_Homo sapiens_hsa041220.23410375
125NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22618091
126N-Glycan biosynthesis_Homo sapiens_hsa005100.22227413
127Phenylalanine metabolism_Homo sapiens_hsa003600.22014017
128Asthma_Homo sapiens_hsa053100.19621198
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.19604805
130Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.19066209
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18629074
132Retinol metabolism_Homo sapiens_hsa008300.18552534
133Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.18157966
134Hematopoietic cell lineage_Homo sapiens_hsa046400.17413352
135Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16379870
136Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.16032836
137Basal cell carcinoma_Homo sapiens_hsa052170.15807550
138Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.13164947
139Glycosaminoglycan degradation_Homo sapiens_hsa005310.13002861
140Renin-angiotensin system_Homo sapiens_hsa046140.12497335
141Circadian rhythm_Homo sapiens_hsa047100.11444470
142Cyanoamino acid metabolism_Homo sapiens_hsa004600.11140749
143Arginine and proline metabolism_Homo sapiens_hsa003300.09559034
144Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.09545818
145Steroid hormone biosynthesis_Homo sapiens_hsa001400.08547975
146Maturity onset diabetes of the young_Homo sapiens_hsa049500.08200174
147Alcoholism_Homo sapiens_hsa050340.07862445

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