CCDC18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tRNA methylation (GO:0030488)9.98582640
2regulation of DNA methylation (GO:0044030)7.17380708
3N-terminal protein amino acid acetylation (GO:0006474)6.96556605
4DNA methylation involved in gamete generation (GO:0043046)6.72413270
5DNA methylation (GO:0006306)6.10114704
6DNA alkylation (GO:0006305)6.10114704
7regulation of gene expression by genetic imprinting (GO:0006349)5.82918692
8attachment of spindle microtubules to kinetochore (GO:0008608)5.53813352
9urate metabolic process (GO:0046415)5.44186826
10positive regulation of gluconeogenesis (GO:0045722)5.43484514
11IMP metabolic process (GO:0046040)5.15433543
12mitotic chromosome condensation (GO:0007076)5.13057052
13prostate gland growth (GO:0060736)5.09140096
14DNA methylation or demethylation (GO:0044728)4.93100099
15DNA ligation (GO:0006266)4.78972761
16CENP-A containing nucleosome assembly (GO:0034080)4.75011622
17DNA double-strand break processing (GO:0000729)4.71806585
18mitotic sister chromatid segregation (GO:0000070)4.66187670
19RNA methylation (GO:0001510)4.63512120
20chromatin remodeling at centromere (GO:0031055)4.63286346
21natural killer cell mediated cytotoxicity (GO:0042267)4.61877364
22natural killer cell mediated immunity (GO:0002228)4.61877364
23centriole replication (GO:0007099)4.58682124
24replication fork processing (GO:0031297)4.55946502
25regulation of cholesterol biosynthetic process (GO:0045540)4.55132405
26DNA topological change (GO:0006265)4.46301979
27sister chromatid segregation (GO:0000819)4.45025098
28defense response to protozoan (GO:0042832)4.44011130
29histone-serine phosphorylation (GO:0035404)4.41505853
30protein localization to kinetochore (GO:0034501)4.41377678
31DNA replication checkpoint (GO:0000076)4.34935322
32kinetochore organization (GO:0051383)4.33618843
33genetic imprinting (GO:0071514)4.30949645
34maturation of 5.8S rRNA (GO:0000460)4.29295217
35spliceosomal snRNP assembly (GO:0000387)4.28171894
36ncRNA 3-end processing (GO:0043628)4.18264290
37mitotic metaphase plate congression (GO:0007080)4.17410553
38DNA modification (GO:0006304)4.14648564
39regulation of DNA endoreduplication (GO:0032875)4.13381670
40meiotic chromosome segregation (GO:0045132)4.10163966
41synapsis (GO:0007129)4.08162742
42regulation of mitotic spindle organization (GO:0060236)4.06597941
43histone exchange (GO:0043486)4.05679298
44regulation of translation in response to stress (GO:0043555)4.05531324
45regulation of centriole replication (GO:0046599)4.05154551
46neutrophil mediated immunity (GO:0002446)4.03377306
47histone H3-K9 modification (GO:0061647)4.01150801
48protein localization to chromosome, centromeric region (GO:0071459)3.99626707
49negative regulation of DNA-dependent DNA replication (GO:2000104)3.98397345
50regulation of spindle organization (GO:0090224)3.97947262
51DNA replication-independent nucleosome assembly (GO:0006336)3.95759293
52DNA replication-independent nucleosome organization (GO:0034724)3.95759293
53regulation of mitotic spindle checkpoint (GO:1903504)3.94985604
54regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.94985604
55regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.94465460
56phospholipid homeostasis (GO:0055091)3.93342281
57maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.92058827
58mitotic sister chromatid cohesion (GO:0007064)3.89176740
59protein K6-linked ubiquitination (GO:0085020)3.89025993
60cellular response to ethanol (GO:0071361)3.87967205
61response to protozoan (GO:0001562)3.86685217
62nuclear pore complex assembly (GO:0051292)3.84327971
63epithelial cell differentiation involved in prostate gland development (GO:0060742)3.82425744
64metaphase plate congression (GO:0051310)3.81081708
65regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.76411551
66resolution of meiotic recombination intermediates (GO:0000712)3.75880567
67histone lysine demethylation (GO:0070076)3.73225815
68AMP metabolic process (GO:0046033)3.70189347
69ribonucleoprotein complex disassembly (GO:0032988)3.69043521
70regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.67878008
71exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.67616645
72microtubule depolymerization (GO:0007019)3.67153038
73recombinational repair (GO:0000725)3.66051733
74formation of translation preinitiation complex (GO:0001731)3.65549153
75nucleotide-excision repair, DNA gap filling (GO:0006297)3.65432350
76protein localization to chromosome (GO:0034502)3.63742871
77protein polyglutamylation (GO:0018095)3.62872727
78double-strand break repair via homologous recombination (GO:0000724)3.61852149
79mitotic G2 DNA damage checkpoint (GO:0007095)3.54611707
80spindle checkpoint (GO:0031577)3.53913738
81establishment of chromosome localization (GO:0051303)3.53666599
82nuclear pore organization (GO:0006999)3.51785652
83regulation of mitotic metaphase/anaphase transition (GO:0030071)3.48321017
84histone demethylation (GO:0016577)3.47994358
85centrosome organization (GO:0051297)3.47556754
86interkinetic nuclear migration (GO:0022027)3.47147548
87mitotic recombination (GO:0006312)3.46685921
88spindle assembly checkpoint (GO:0071173)3.46527975
89telomere maintenance via recombination (GO:0000722)3.46193720
90regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.42359545
91regulation of centrosome cycle (GO:0046605)3.41553058
92negative regulation of sister chromatid segregation (GO:0033046)3.40771539
93negative regulation of mitotic sister chromatid separation (GO:2000816)3.40771539
94negative regulation of mitotic sister chromatid segregation (GO:0033048)3.40771539
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.40771539
96nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.40361844
97non-recombinational repair (GO:0000726)3.39460879
98double-strand break repair via nonhomologous end joining (GO:0006303)3.39460879
99negative regulation of chromosome segregation (GO:0051985)3.39098964
100organelle disassembly (GO:1903008)3.38515134
101DNA unwinding involved in DNA replication (GO:0006268)3.38317811
102oocyte maturation (GO:0001556)3.37126035
103DNA replication initiation (GO:0006270)3.36987720
104DNA catabolic process, exonucleolytic (GO:0000738)3.35600201
105DNA replication-dependent nucleosome assembly (GO:0006335)3.34179388
106DNA replication-dependent nucleosome organization (GO:0034723)3.34179388
107negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.33278736
108regulation of protein glycosylation (GO:0060049)3.32413657
109chromatin assembly or disassembly (GO:0006333)3.31801012
110kinetochore assembly (GO:0051382)3.31419391
111endothelial cell chemotaxis (GO:0035767)3.30675477
112cellular response to electrical stimulus (GO:0071257)3.30623858
113DNA strand elongation involved in DNA replication (GO:0006271)3.29995682
114regulation of cAMP-dependent protein kinase activity (GO:2000479)3.29075325
115mitotic spindle assembly checkpoint (GO:0007094)3.28593196
116somatic diversification of immune receptors via somatic mutation (GO:0002566)3.28484108
117somatic hypermutation of immunoglobulin genes (GO:0016446)3.28484108
118ribosomal small subunit assembly (GO:0000028)3.27027115
119RNA-dependent DNA replication (GO:0006278)3.25272360
120tRNA modification (GO:0006400)3.25263514
121regulation of mitotic sister chromatid separation (GO:0010965)3.23130485
122regulation of mitotic sister chromatid segregation (GO:0033047)3.23130485
123regulation of sister chromatid segregation (GO:0033045)3.23130485
124protein neddylation (GO:0045116)3.23072170
125telomere maintenance via semi-conservative replication (GO:0032201)3.21583530
126regulation of chromosome segregation (GO:0051983)3.19862783
127ATP-dependent chromatin remodeling (GO:0043044)3.19664179
128chromosome condensation (GO:0030261)3.19128445
129negative regulation of mitosis (GO:0045839)3.17692186
130membrane disassembly (GO:0030397)3.16461133
131nuclear envelope disassembly (GO:0051081)3.16461133
132cardiac muscle cell development (GO:0055013)3.14980675
133mitotic nuclear envelope disassembly (GO:0007077)3.14315634
134chromosome segregation (GO:0007059)3.14034250
135DNA packaging (GO:0006323)3.13766015
136centriole assembly (GO:0098534)3.13652495
137negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.13615207
138regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.12996182
139mitotic G2/M transition checkpoint (GO:0044818)3.12253581
140negative regulation of DNA recombination (GO:0045910)3.11818216
141microtubule organizing center organization (GO:0031023)3.11695547
142mitotic spindle checkpoint (GO:0071174)3.11553124
143mismatch repair (GO:0006298)3.10259264
144positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.10224585
145positive regulation of mitotic sister chromatid separation (GO:1901970)3.10224585
146positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.10224585
147telomere maintenance via telomere lengthening (GO:0010833)3.08985169
148chromosome organization involved in meiosis (GO:0070192)3.08143963
149DNA strand elongation (GO:0022616)3.08060974
150positive regulation of chromosome segregation (GO:0051984)3.06710089
151positive regulation of histone H3-K4 methylation (GO:0051571)3.05040552
152regulation of centrosome duplication (GO:0010824)3.04806697
153double-strand break repair (GO:0006302)3.03264399

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.51077997
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.07590513
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.23458207
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.26547391
5MYC_18555785_ChIP-Seq_MESCs_Mouse2.99343810
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.81753109
7AR_21909140_ChIP-Seq_LNCAP_Human2.70322358
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.64613905
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.60608367
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.44930239
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.37730807
12CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.36411883
13KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.32678603
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.29976860
15TP63_19390658_ChIP-ChIP_HaCaT_Human2.29448086
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.28020417
17SCL_19346495_ChIP-Seq_HPC-7_Human2.23381643
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21568255
19IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19324393
20VDR_23849224_ChIP-Seq_CD4+_Human2.18335946
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.08476687
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.04616154
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04068835
24* ELK1_19687146_ChIP-ChIP_HELA_Human2.02285177
25E2F7_22180533_ChIP-Seq_HELA_Human10.4479623
26TTF2_22483619_ChIP-Seq_HELA_Human1.99136318
27KDM5A_27292631_Chip-Seq_BREAST_Human1.95918739
28* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91380561
29XRN2_22483619_ChIP-Seq_HELA_Human1.84355249
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.81518110
31FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79740830
32MYC_18940864_ChIP-ChIP_HL60_Human1.74773665
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.74606133
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.72428520
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.72206034
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68160819
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.61485236
38* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58659380
39VDR_22108803_ChIP-Seq_LS180_Human1.57505415
40NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55282602
41SOX2_18555785_ChIP-Seq_MESCs_Mouse1.54145593
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53468210
43NELFA_20434984_ChIP-Seq_ESCs_Mouse1.52557603
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.52249092
45FOXP3_21729870_ChIP-Seq_TREG_Human1.52087369
46E2F1_18555785_ChIP-Seq_MESCs_Mouse1.51647377
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.47771880
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.45763165
49POU3F2_20337985_ChIP-ChIP_501MEL_Human1.43984045
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41826387
51* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.38829486
52POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.38167142
53MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.34986259
54TAF15_26573619_Chip-Seq_HEK293_Human1.33828496
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32278764
56DCP1A_22483619_ChIP-Seq_HELA_Human1.31328352
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.30147889
58* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.30007752
59CIITA_25753668_ChIP-Seq_RAJI_Human1.21860513
60IGF1R_20145208_ChIP-Seq_DFB_Human1.20925710
61GABP_17652178_ChIP-ChIP_JURKAT_Human1.20551855
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.18349256
63KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.18349256
64KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.18349256
65POU5F1_16153702_ChIP-ChIP_HESCs_Human1.16814331
66IRF8_21731497_ChIP-ChIP_J774_Mouse1.16494954
67IRF1_19129219_ChIP-ChIP_H3396_Human1.16114447
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14806206
69* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.14341751
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13204534
71* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11854642
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.10559604
73BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.10322803
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09623035
75NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07902318
76EWS_26573619_Chip-Seq_HEK293_Human1.05881035
77GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03575037
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01734987
79JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.01633039
80GABP_19822575_ChIP-Seq_HepG2_Human1.01533551
81STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00968490
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.00338719
83SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00147590
84SOX2_16153702_ChIP-ChIP_HESCs_Human0.99762263
85EZH2_27294783_Chip-Seq_NPCs_Mouse0.97990617
86FUS_26573619_Chip-Seq_HEK293_Human0.96505564
87P300_19829295_ChIP-Seq_ESCs_Human0.94970452
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.94738598
89LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.94352161
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.93756694
91* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93389213
92ZNF274_21170338_ChIP-Seq_K562_Hela0.93368169
93HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.93209766
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92942608
95MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.92700843
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92390095
97NANOG_16153702_ChIP-ChIP_HESCs_Human0.91387051
98* THAP11_20581084_ChIP-Seq_MESCs_Mouse0.91375587
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.88888615
100ZFX_18555785_ChIP-Seq_MESCs_Mouse0.87642008
101SPI1_23547873_ChIP-Seq_NB4_Human0.87409899
102EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.85822977
103EGR1_23403033_ChIP-Seq_LIVER_Mouse0.85609869
104PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.84911576
105* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.82478673
106NFE2_27457419_Chip-Seq_LIVER_Mouse0.82431465
107RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81218685
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.79938730
109SUZ12_27294783_Chip-Seq_NPCs_Mouse0.79647960
110RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.79523240
111ER_23166858_ChIP-Seq_MCF-7_Human0.78910522
112CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.78807509
113PADI4_21655091_ChIP-ChIP_MCF-7_Human0.78583101
114RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.77097668
115CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.76915068
116SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.74310196
117* MYB_26560356_Chip-Seq_TH1_Human0.74198015
118STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.74117431
119PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.73953705
120FLI1_27457419_Chip-Seq_LIVER_Mouse0.73214770
121MYB_26560356_Chip-Seq_TH2_Human0.73171993
122PCGF2_27294783_Chip-Seq_NPCs_Mouse0.71445938
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.71287229
124ESR1_21235772_ChIP-Seq_MCF-7_Human0.71061100
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70293832
126TP53_22573176_ChIP-Seq_HFKS_Human0.70052040
127KLF4_18555785_ChIP-Seq_MESCs_Mouse0.69911767
128SALL4_22934838_ChIP-ChIP_CD34+_Human0.69783413
129UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.69474699
130* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.69073369
131CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.68667997
132POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.68623249
133SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.67971973
134GATA2_21666600_ChIP-Seq_HMVEC_Human0.65751060

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode8.72114748
2MP0004510_myositis8.10535150
3MP0000569_abnormal_digit_pigmentation6.08680499
4MP0009697_abnormal_copulation5.47485428
5MP0003123_paternal_imprinting5.35172530
6MP0003890_abnormal_embryonic-extraembry3.40602871
7MP0003279_aneurysm3.39495422
8MP0000749_muscle_degeneration3.07460905
9MP0003718_maternal_effect2.49585035
10MP0005408_hypopigmentation2.47944269
11MP0002166_altered_tumor_susceptibility2.28594310
12MP0003693_abnormal_embryo_hatching2.17722637
13MP0002006_tumorigenesis2.11144554
14MP0010094_abnormal_chromosome_stability2.09188045
15MP0004808_abnormal_hematopoietic_stem2.05861281
16MP0001293_anophthalmia2.05273453
17MP0004957_abnormal_blastocyst_morpholog2.04938460
18MP0003121_genomic_imprinting2.02945431
19MP0004381_abnormal_hair_follicle1.93044640
20MP0000372_irregular_coat_pigmentation1.87658345
21MP0001919_abnormal_reproductive_system1.85880162
22MP0008007_abnormal_cellular_replicative1.82903506
23MP0005174_abnormal_tail_pigmentation1.75663989
24MP0006072_abnormal_retinal_apoptosis1.60433725
25MP0005075_abnormal_melanosome_morpholog1.58716224
26MP0003077_abnormal_cell_cycle1.57123132
27MP0003111_abnormal_nucleus_morphology1.50358813
28MP0003787_abnormal_imprinting1.48800577
29MP0000015_abnormal_ear_pigmentation1.44294636
30MP0008057_abnormal_DNA_replication1.44088723
31MP0001835_abnormal_antigen_presentation1.42482494
32MP0005389_reproductive_system_phenotype1.40301806
33MP0003937_abnormal_limbs/digits/tail_de1.33217023
34MP0001958_emphysema1.18265162
35MP0002108_abnormal_muscle_morphology1.16071292
36MP0008058_abnormal_DNA_repair1.12419133
37MP0002102_abnormal_ear_morphology1.10957275
38MP0008789_abnormal_olfactory_epithelium1.09954576
39MP0005671_abnormal_response_to1.09114239
40MP0008995_early_reproductive_senescence1.08979397
41MP0000767_abnormal_smooth_muscle1.07906253
42MP0006036_abnormal_mitochondrial_physio1.07584964
43MP0002877_abnormal_melanocyte_morpholog1.07439648
44MP0004197_abnormal_fetal_growth/weight/1.07413689
45MP0000631_abnormal_neuroendocrine_gland1.06060758
46MP0003186_abnormal_redox_activity1.06054191
47MP0008932_abnormal_embryonic_tissue1.05149251
48MP0008877_abnormal_DNA_methylation1.02059724
49MP0006035_abnormal_mitochondrial_morpho1.01761964
50MP0002084_abnormal_developmental_patter0.98732120
51MP0002210_abnormal_sex_determination0.97915451
52MP0005253_abnormal_eye_physiology0.97027147
53MP0003656_abnormal_erythrocyte_physiolo0.96035973
54MP0001730_embryonic_growth_arrest0.95848267
55MP0003646_muscle_fatigue0.95791091
56MP0002085_abnormal_embryonic_tissue0.95587798
57MP0003984_embryonic_growth_retardation0.95417710
58MP0003172_abnormal_lysosome_physiology0.94944953
59MP0003136_yellow_coat_color0.94655864
60MP0009703_decreased_birth_body0.92910952
61MP0002088_abnormal_embryonic_growth/wei0.91775212
62MP0000358_abnormal_cell_content/0.89652266
63MP0001764_abnormal_homeostasis0.88233388
64MP0005464_abnormal_platelet_physiology0.82204953
65MP0005084_abnormal_gallbladder_morpholo0.81267453
66MP0005330_cardiomyopathy0.80214620
67MP0002233_abnormal_nose_morphology0.78977676
68MP0005391_vision/eye_phenotype0.78698145
69MP0001145_abnormal_male_reproductive0.77096155
70MP0000428_abnormal_craniofacial_morphol0.76593534
71MP0003567_abnormal_fetal_cardiomyocyte0.76530297
72MP0002269_muscular_atrophy0.76382910
73MP0003806_abnormal_nucleotide_metabolis0.74726647
74MP0001119_abnormal_female_reproductive0.74278174
75MP0005499_abnormal_olfactory_system0.74252429
76MP0005394_taste/olfaction_phenotype0.74252429
77MP0002396_abnormal_hematopoietic_system0.74200658
78MP0003943_abnormal_hepatobiliary_system0.73195480
79MP0003724_increased_susceptibility_to0.71534604
80MP0000383_abnormal_hair_follicle0.71405891
81MP0009672_abnormal_birth_weight0.70932165
82MP0002160_abnormal_reproductive_system0.70366080
83MP0001697_abnormal_embryo_size0.70246802
84MP0003786_premature_aging0.69956859
85MP0002009_preneoplasia0.69878664
86MP0010307_abnormal_tumor_latency0.69061465
87MP0002095_abnormal_skin_pigmentation0.69031992
88MP0002111_abnormal_tail_morphology0.68909934
89MP0000653_abnormal_sex_gland0.68380539
90MP0001929_abnormal_gametogenesis0.67345842
91MP0005395_other_phenotype0.67033094
92MP0000427_abnormal_hair_cycle0.66412289
93MP0002234_abnormal_pharynx_morphology0.66180691
94MP0005647_abnormal_sex_gland0.66069813
95MP0001485_abnormal_pinna_reflex0.63489448
96MP0001529_abnormal_vocalization0.63278167
97MP0002092_abnormal_eye_morphology0.63125041
98MP0002398_abnormal_bone_marrow0.62946794
99MP0001243_abnormal_dermal_layer0.62854259
100MP0003763_abnormal_thymus_physiology0.62608386
101MP0000350_abnormal_cell_proliferation0.62139600
102MP0005410_abnormal_fertilization0.61478119
103MP0003699_abnormal_female_reproductive0.60197393
104MP0005551_abnormal_eye_electrophysiolog0.59676148
105MP0001545_abnormal_hematopoietic_system0.59065128
106MP0005397_hematopoietic_system_phenotyp0.59065128
107MP0005623_abnormal_meninges_morphology0.58188677
108MP0001501_abnormal_sleep_pattern0.57737654
109MP0000371_diluted_coat_color0.57598795
110MP0001672_abnormal_embryogenesis/_devel0.57496051
111MP0005380_embryogenesis_phenotype0.57496051
112MP0001800_abnormal_humoral_immune0.56580501
113MP0000647_abnormal_sebaceous_gland0.56510366
114MP0005266_abnormal_metabolism0.56342864
115MP0005384_cellular_phenotype0.56068425
116MP0000490_abnormal_crypts_of0.55682402
117MP0000858_altered_metastatic_potential0.55533184
118MP0002019_abnormal_tumor_incidence0.48997089
119MP0003448_altered_tumor_morphology0.48688502
120MP0004147_increased_porphyrin_level0.48493448
121MP0003698_abnormal_male_reproductive0.48342637
122MP0002722_abnormal_immune_system0.47763778
123MP0002086_abnormal_extraembryonic_tissu0.47615852
124MP0002249_abnormal_larynx_morphology0.47179829
125MP0002697_abnormal_eye_size0.46984581
126MP0002080_prenatal_lethality0.46507225
127MP0001286_abnormal_eye_development0.45974134
128MP0003453_abnormal_keratinocyte_physiol0.45729223
129MP0000689_abnormal_spleen_morphology0.44997716
130MP0002429_abnormal_blood_cell0.43104840
131MP0001346_abnormal_lacrimal_gland0.43048207
132MP0000703_abnormal_thymus_morphology0.42891790
133MP0000716_abnormal_immune_system0.42271320
134MP0000627_abnormal_mammary_gland0.42023198
135MP0002938_white_spotting0.41933852
136MP0002161_abnormal_fertility/fecundity0.40502051
137MP0000313_abnormal_cell_death0.38880792
138MP0003936_abnormal_reproductive_system0.37042257
139MP0002075_abnormal_coat/hair_pigmentati0.33675615
140MP0009785_altered_susceptibility_to0.33405450
141MP0010352_gastrointestinal_tract_polyps0.32037868

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the musculature of the pelvis (HP:0001469)9.46689026
2Abnormality of the hip-girdle musculature (HP:0001445)9.46689026
3Limb-girdle muscle atrophy (HP:0003797)9.02079680
4Fair hair (HP:0002286)5.65102273
5Meckel diverticulum (HP:0002245)4.94078151
6Abnormality of the preputium (HP:0100587)4.91390708
7Generalized hypopigmentation of hair (HP:0011358)4.87372081
8Aplasia/Hypoplasia of the uvula (HP:0010293)4.86648690
9Abnormality of the calf musculature (HP:0001430)4.79912900
10Proximal amyotrophy (HP:0007126)4.77158515
11Abnormality of chromosome stability (HP:0003220)4.64863266
12Limb-girdle muscle weakness (HP:0003325)4.63982191
13Abnormality of the ileum (HP:0001549)4.60071854
14Scapular winging (HP:0003691)4.39910642
15Duodenal stenosis (HP:0100867)4.10772430
16Small intestinal stenosis (HP:0012848)4.10772430
17Breast hypoplasia (HP:0003187)4.04127070
18Clubbing of toes (HP:0100760)4.03830139
19Selective tooth agenesis (HP:0001592)3.71931197
20Abnormality of the carotid arteries (HP:0005344)3.61547633
21Clumsiness (HP:0002312)3.54977868
22Protruding tongue (HP:0010808)3.50365947
23Recurrent bacterial skin infections (HP:0005406)3.49417082
24Inappropriate behavior (HP:0000719)3.46726683
25Flat occiput (HP:0005469)3.46269338
26Myelodysplasia (HP:0002863)3.37351000
27Periodontitis (HP:0000704)3.29895672
28Abnormality of the duodenum (HP:0002246)3.26876842
29Recurrent abscess formation (HP:0002722)3.21976735
30Ectopic kidney (HP:0000086)3.19323780
31Abnormal lung lobation (HP:0002101)3.09204505
32Supernumerary bones of the axial skeleton (HP:0009144)2.91449894
33Bone marrow hypocellularity (HP:0005528)2.90447576
34Gingival bleeding (HP:0000225)2.86885594
35Supernumerary ribs (HP:0005815)2.80432127
36Abnormality of the shoulder girdle musculature (HP:0001435)2.79528533
37Colon cancer (HP:0003003)2.77194845
38Abnormal number of incisors (HP:0011064)2.75678372
39Rhabdomyosarcoma (HP:0002859)2.75667851
40Aplasia/Hypoplasia of the macula (HP:0008059)2.73993255
41Broad-based gait (HP:0002136)2.71556602
42Leukopenia (HP:0001882)2.70917113
43Exotropia (HP:0000577)2.60630579
44Chromsome breakage (HP:0040012)2.56956544
45Petechiae (HP:0000967)2.54173912
46Nephroblastoma (Wilms tumor) (HP:0002667)2.49818462
47Birth length less than 3rd percentile (HP:0003561)2.46660122
48Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.46191589
49Neurodegeneration (HP:0002180)2.45769178
50Sloping forehead (HP:0000340)2.44554835
51Absent thumb (HP:0009777)2.43944108
52Absent speech (HP:0001344)2.43221239
53Aplasia/Hypoplasia affecting the retina (HP:0008061)2.42288139
54Aplasia/Hypoplasia of the sacrum (HP:0008517)2.40270302
55Acute necrotizing encephalopathy (HP:0006965)2.38623139
56Oligodactyly (hands) (HP:0001180)2.35908126
57Abnormality of midbrain morphology (HP:0002418)2.30177776
58Molar tooth sign on MRI (HP:0002419)2.30177776
59Embryonal renal neoplasm (HP:0011794)2.29919412
60Widely spaced teeth (HP:0000687)2.29649082
61Acute encephalopathy (HP:0006846)2.28767178
62Blue irides (HP:0000635)2.27777592
63Triphalangeal thumb (HP:0001199)2.22309028
64Ridged nail (HP:0001807)2.22100600
65Pancreatic fibrosis (HP:0100732)2.20291807
66Supernumerary spleens (HP:0009799)2.20052367
67Pancreatic cysts (HP:0001737)2.18848331
68Ependymoma (HP:0002888)2.18417956
69Absent radius (HP:0003974)2.17095085
70Dyschromatopsia (HP:0007641)2.15330789
71Increased hepatocellular lipid droplets (HP:0006565)2.13330270
72Absent forearm bone (HP:0003953)2.11664331
73Aplasia involving forearm bones (HP:0009822)2.11664331
74Abnormality of DNA repair (HP:0003254)2.11215917
75Postnatal microcephaly (HP:0005484)2.10548250
76Duplicated collecting system (HP:0000081)2.09876878
77Glioma (HP:0009733)2.06772774
78Type 2 muscle fiber atrophy (HP:0003554)2.05938716
79Granulocytopenia (HP:0001913)2.05870457
80Arteriovenous malformation (HP:0100026)2.04570194
81Abnormal mitochondria in muscle tissue (HP:0008316)2.04202988
82Hemorrhage of the eye (HP:0011885)2.03073149
83Increased nuchal translucency (HP:0010880)2.02462279
84Abnormality of the incisor (HP:0000676)2.02145172
85Aplastic anemia (HP:0001915)2.01953893
86Chromosomal breakage induced by crosslinking agents (HP:0003221)2.01725130
87Neoplasm of the colon (HP:0100273)2.01673661
88Abnormality of the renal collecting system (HP:0004742)2.01135878
89Tracheoesophageal fistula (HP:0002575)2.00929384
90Hypoplastic pelvis (HP:0008839)1.99974222
91Abnormality of lateral ventricle (HP:0030047)1.99916581
92Increased CSF lactate (HP:0002490)1.99588443
93Mitochondrial inheritance (HP:0001427)1.96876453
94Nonprogressive disorder (HP:0003680)1.96294680
95Small hand (HP:0200055)1.96014971
96Horseshoe kidney (HP:0000085)1.95879216
97Microretrognathia (HP:0000308)1.95296152
98Volvulus (HP:0002580)1.94870595
99Progressive macrocephaly (HP:0004481)1.94640696
100Astigmatism (HP:0000483)1.92907873
101Cortical dysplasia (HP:0002539)1.92247357
102Long clavicles (HP:0000890)1.91959919
103Lipid accumulation in hepatocytes (HP:0006561)1.91666072
104Drooling (HP:0002307)1.90862694
105Excessive salivation (HP:0003781)1.90862694
106Chronic hepatic failure (HP:0100626)1.90787200
107Breast aplasia (HP:0100783)1.90479008
108Cerebral edema (HP:0002181)1.89797577
109Hypoplasia of the maxilla (HP:0000327)1.87932059
110Cafe-au-lait spot (HP:0000957)1.87624899
111Acute lymphatic leukemia (HP:0006721)1.87139698
112Hypopigmented skin patches (HP:0001053)1.86773170
113Intestinal atresia (HP:0011100)1.86728785
114Combined immunodeficiency (HP:0005387)1.84492741
115Oligodactyly (HP:0012165)1.84484294
116Nephronophthisis (HP:0000090)1.84421521
117Aplasia/Hypoplasia of the patella (HP:0006498)1.83973411
118Abnormality of cells of the erythroid lineage (HP:0012130)1.83348337
119Premature graying of hair (HP:0002216)1.82858090
120Muscle fiber atrophy (HP:0100295)1.82542142
121Eosinophilia (HP:0001880)1.79642153
122Impulsivity (HP:0100710)1.79541322
123Short thumb (HP:0009778)1.79525347
124Gingivitis (HP:0000230)1.78230174
125Abnormality of the fingertips (HP:0001211)1.77154023
126Myokymia (HP:0002411)1.77149714
127Patellar aplasia (HP:0006443)1.77128982
128True hermaphroditism (HP:0010459)1.76049832
129Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.75353960
130Short 4th metacarpal (HP:0010044)1.75353960
131Abnormal spermatogenesis (HP:0008669)1.74584111
132Hypoplastic iliac wings (HP:0002866)1.74204068
133Reticulocytopenia (HP:0001896)1.73947327
134Panhypogammaglobulinemia (HP:0003139)1.73870279
135Aplasia/Hypoplasia of the breasts (HP:0010311)1.73316534
136Aplasia/Hypoplasia of the sternum (HP:0006714)1.73238109
137Hypoglycemic coma (HP:0001325)1.72318070
138Basal ganglia calcification (HP:0002135)1.71260508
139Neoplasm of striated muscle (HP:0009728)1.69714544
140Abnormal platelet volume (HP:0011876)1.69390789
141Astrocytoma (HP:0009592)1.69192608
142Abnormality of the astrocytes (HP:0100707)1.69192608
143Hepatocellular necrosis (HP:0001404)1.68448108
144Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.68434784
145Abnormality of alanine metabolism (HP:0010916)1.68434784
146Hyperalaninemia (HP:0003348)1.68434784
147Medulloblastoma (HP:0002885)1.67188449
148Medial flaring of the eyebrow (HP:0010747)1.67122377
149Elevated erythrocyte sedimentation rate (HP:0003565)1.66652393
150Ovarian neoplasm (HP:0100615)1.65430163
151Abnormal delayed hypersensitivity skin test (HP:0002963)1.65081404
152Abnormality of the labia minora (HP:0012880)1.64925632
153Aplasia/Hypoplasia of the earlobes (HP:0009906)1.63846662
154Hypoplasia of the pons (HP:0012110)1.63744936
155Embryonal neoplasm (HP:0002898)1.63272071
156Pancytopenia (HP:0001876)1.63170565
157Median cleft lip (HP:0000161)1.62528861
158Dandy-Walker malformation (HP:0001305)1.62486666
159IgM deficiency (HP:0002850)1.62426576
160Ocular albinism (HP:0001107)1.62116365
161Stenosis of the external auditory canal (HP:0000402)1.61122260
162B lymphocytopenia (HP:0010976)1.61111379
163Hemivertebrae (HP:0002937)1.59444978
164Choanal atresia (HP:0000453)1.59429060
165Abnormality of incisor morphology (HP:0011063)1.56264652
166Acute myeloid leukemia (HP:0004808)1.53862136
167Chronic otitis media (HP:0000389)1.52526454
168Tetralogy of Fallot (HP:0001636)1.51195889

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB16.19441695
2BRSK26.10648460
3STK165.83438366
4CAMKK24.79061034
5MUSK3.68565428
6MST43.44680484
7CDK73.13588776
8BRSK12.96857822
9NUAK12.22989988
10CDC72.18291344
11PNCK2.15696361
12BMPR1B1.86437026
13TNIK1.83535593
14MAP3K81.76960694
15EPHB11.76591473
16PLK41.75517192
17PBK1.70780874
18CAMKK11.68763311
19CDK41.66589029
20RPS6KA41.65883531
21ACVR1B1.60256748
22WEE11.56605084
23FRK1.54499218
24TAF11.54251651
25ATR1.52429076
26MAP4K11.50195587
27CDK91.49002608
28VRK21.46518895
29TTK1.46081921
30EIF2AK31.37980013
31NEK21.34733952
32TXK1.24043481
33VRK11.23597049
34MKNK11.23480031
35PLK21.18687435
36STK111.17014853
37SRPK11.13161631
38CDK121.13003249
39CDK61.08040427
40MAP4K21.06134282
41BRD40.99926577
42PLK10.99289855
43WNK30.99108906
44TRIM280.98014659
45MARK30.97689339
46RPS6KL10.96856462
47RPS6KC10.96856462
48NEK10.96776504
49MELK0.94134043
50MKNK20.93213966
51AURKB0.92616559
52STK390.87604772
53RPS6KA20.84898454
54CHEK20.80121539
55RPS6KA60.79382552
56RPS6KB20.76494129
57PAK40.75885625
58RPS6KB10.75772475
59BTK0.73425798
60CDK30.72892264
61PLK30.71866246
62WNK40.70391570
63GRK10.70117218
64PDK10.69459882
65IKBKB0.67178116
66PDK20.65675424
67STK40.62843589
68ERBB30.62790720
69PIM10.62550765
70CLK10.61859048
71OXSR10.61327876
72NEK90.60937677
73FLT30.59592118
74BRAF0.58759590
75YES10.58668725
76CAMK1G0.56976384
77MAP3K100.55329851
78CDK80.54345574
79CSF1R0.52949157
80NLK0.48580165
81NME10.48403539
82ALK0.47234735
83DYRK30.47032657
84PDPK10.46908101
85MAPK40.46787586
86ZAK0.46378696
87STK100.46346921
88TGFBR10.44093158
89STK38L0.42013556
90MAP3K40.41658891
91TAOK30.41610780
92ATM0.40718530
93MAP3K120.39526687
94SCYL20.39357929
95PRKACB0.39267997
96NEK60.39178257
97EIF2AK20.39156576
98RPS6KA50.38785330
99CDK20.38298324
100INSRR0.37387387
101MAPK130.36154481
102CSNK2A10.34268540
103AKT30.33760001
104FGFR30.32584197
105CDK10.32092787
106CCNB10.31523426
107TSSK60.31300223
108LATS10.31118053
109STK240.30896585
110EIF2AK10.30815245
111CSNK1E0.30098870
112TLK10.30011412
113PRKAA10.29071388
114PTK2B0.28719222
115PINK10.28693358
116NME20.28555269
117CHEK10.28470340
118UHMK10.28286727
119EPHA30.28233522
120PASK0.28042116
121DYRK20.26923770
122CSK0.25754691
123PIK3CG0.25510471
124CSNK2A20.23689031
125PRKG20.23159380
126ADRBK20.23143985
127STK30.23022282
128HIPK20.22803648
129PRKDC0.22598256
130HCK0.21817834
131PIK3CA0.21726689
132ERBB20.21725662
133AURKA0.20544687
134PKN10.20168588
135PRKAA20.19421960
136TEC0.17469840
137LRRK20.16756967
138SYK0.16592762
139MAPK30.14158968
140BMPR20.13867060
141EPHA20.13175316

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009106.21329273
2DNA replication_Homo sapiens_hsa030304.12591391
3Fanconi anemia pathway_Homo sapiens_hsa034603.78410647
4Mismatch repair_Homo sapiens_hsa034303.37957736
5Homologous recombination_Homo sapiens_hsa034403.21681328
6RNA transport_Homo sapiens_hsa030133.17566946
7Viral myocarditis_Homo sapiens_hsa054163.09656619
8Cell cycle_Homo sapiens_hsa041102.99287800
9RNA degradation_Homo sapiens_hsa030182.82130798
10Ribosome_Homo sapiens_hsa030102.75247669
11Spliceosome_Homo sapiens_hsa030402.64129843
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.18515635
13Non-homologous end-joining_Homo sapiens_hsa034502.02147545
14Base excision repair_Homo sapiens_hsa034101.98688997
15Nucleotide excision repair_Homo sapiens_hsa034201.88621802
16Oocyte meiosis_Homo sapiens_hsa041141.82307593
17mRNA surveillance pathway_Homo sapiens_hsa030151.75605296
18Pyrimidine metabolism_Homo sapiens_hsa002401.69474718
19Basal transcription factors_Homo sapiens_hsa030221.68344764
20p53 signaling pathway_Homo sapiens_hsa041151.68051996
21Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.67426454
22Viral carcinogenesis_Homo sapiens_hsa052031.62016321
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.57710571
24RNA polymerase_Homo sapiens_hsa030201.57107867
25One carbon pool by folate_Homo sapiens_hsa006701.53441673
26Oxidative phosphorylation_Homo sapiens_hsa001901.49420325
27Parkinsons disease_Homo sapiens_hsa050121.47948131
28Systemic lupus erythematosus_Homo sapiens_hsa053221.47572127
29Primary immunodeficiency_Homo sapiens_hsa053401.45504235
30Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.35325069
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.34927126
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.31168312
33Propanoate metabolism_Homo sapiens_hsa006401.26316323
34Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.25867101
35Notch signaling pathway_Homo sapiens_hsa043301.24173661
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.21969344
37Purine metabolism_Homo sapiens_hsa002301.21914382
38Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.21443507
39Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10417478
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06471325
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04549208
42HTLV-I infection_Homo sapiens_hsa051661.00823944
43Antigen processing and presentation_Homo sapiens_hsa046120.98727780
44Proteasome_Homo sapiens_hsa030500.96588834
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.96365761
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96270920
47Steroid biosynthesis_Homo sapiens_hsa001000.92480749
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90828181
49mTOR signaling pathway_Homo sapiens_hsa041500.89702718
50NOD-like receptor signaling pathway_Homo sapiens_hsa046210.87036852
51Herpes simplex infection_Homo sapiens_hsa051680.86837866
52NF-kappa B signaling pathway_Homo sapiens_hsa040640.83735821
53Dilated cardiomyopathy_Homo sapiens_hsa054140.82601483
54MicroRNAs in cancer_Homo sapiens_hsa052060.81754718
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78675052
56Alzheimers disease_Homo sapiens_hsa050100.72354989
57Small cell lung cancer_Homo sapiens_hsa052220.71176451
58Platelet activation_Homo sapiens_hsa046110.69996148
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.69880970
60Pyruvate metabolism_Homo sapiens_hsa006200.69804398
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69474561
62Epstein-Barr virus infection_Homo sapiens_hsa051690.67073513
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.59253958
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58791799
65Olfactory transduction_Homo sapiens_hsa047400.56491976
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.53012147
67Chronic myeloid leukemia_Homo sapiens_hsa052200.52390236
68Glutathione metabolism_Homo sapiens_hsa004800.52287319
69Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48952783
70Phototransduction_Homo sapiens_hsa047440.47739522
71Fatty acid elongation_Homo sapiens_hsa000620.47239850
72Legionellosis_Homo sapiens_hsa051340.46798317
73Asthma_Homo sapiens_hsa053100.46759682
74Measles_Homo sapiens_hsa051620.45637098
75Hematopoietic cell lineage_Homo sapiens_hsa046400.45591163
76Alcoholism_Homo sapiens_hsa050340.43379019
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42914401
78Acute myeloid leukemia_Homo sapiens_hsa052210.42590712
79Jak-STAT signaling pathway_Homo sapiens_hsa046300.42124200
80Butanoate metabolism_Homo sapiens_hsa006500.42077716
81Leukocyte transendothelial migration_Homo sapiens_hsa046700.41338662
82Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40745346
83Arginine biosynthesis_Homo sapiens_hsa002200.39474814
84Metabolic pathways_Homo sapiens_hsa011000.39422623
85Selenocompound metabolism_Homo sapiens_hsa004500.38226409
86TGF-beta signaling pathway_Homo sapiens_hsa043500.36096970
87Long-term potentiation_Homo sapiens_hsa047200.36081959
88Hedgehog signaling pathway_Homo sapiens_hsa043400.34171001
89Folate biosynthesis_Homo sapiens_hsa007900.33069677
90Lysine degradation_Homo sapiens_hsa003100.32793197
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.32727315
92Basal cell carcinoma_Homo sapiens_hsa052170.32595180
93Hepatitis B_Homo sapiens_hsa051610.31396204
94Huntingtons disease_Homo sapiens_hsa050160.30354724
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.29708146
96Pentose phosphate pathway_Homo sapiens_hsa000300.29499985
97Apoptosis_Homo sapiens_hsa042100.27802079
98Regulation of autophagy_Homo sapiens_hsa041400.26405915
99FoxO signaling pathway_Homo sapiens_hsa040680.25778281
100Wnt signaling pathway_Homo sapiens_hsa043100.22773968
101N-Glycan biosynthesis_Homo sapiens_hsa005100.22017578
102Thyroid cancer_Homo sapiens_hsa052160.21894109
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.20105734
104Pancreatic cancer_Homo sapiens_hsa052120.19218921
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.18412564
106Arachidonic acid metabolism_Homo sapiens_hsa005900.18041317
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.17871600
108Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.17429824
109Fructose and mannose metabolism_Homo sapiens_hsa000510.17404200
110Peroxisome_Homo sapiens_hsa041460.16299574
111Retinol metabolism_Homo sapiens_hsa008300.16193121
112Fatty acid metabolism_Homo sapiens_hsa012120.15273029
113Type I diabetes mellitus_Homo sapiens_hsa049400.15260598
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.14267242
115B cell receptor signaling pathway_Homo sapiens_hsa046620.14105308
116Fatty acid degradation_Homo sapiens_hsa000710.14081664
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13256326
118Shigellosis_Homo sapiens_hsa051310.13191191
119Linoleic acid metabolism_Homo sapiens_hsa005910.12661742
120Protein export_Homo sapiens_hsa030600.12581761
121Drug metabolism - other enzymes_Homo sapiens_hsa009830.12392378
122Caffeine metabolism_Homo sapiens_hsa002320.12331382
123Colorectal cancer_Homo sapiens_hsa052100.10912583
124Hippo signaling pathway_Homo sapiens_hsa043900.10653324
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.10443916
126Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.10158244
127Tryptophan metabolism_Homo sapiens_hsa003800.10016535
128Melanoma_Homo sapiens_hsa052180.09935253
129RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.09859290
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.09850621
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.07156438
132Pathways in cancer_Homo sapiens_hsa052000.07045737
133Biosynthesis of amino acids_Homo sapiens_hsa012300.06731641
134Prostate cancer_Homo sapiens_hsa052150.05411099
135Sulfur relay system_Homo sapiens_hsa041220.04962204
136Intestinal immune network for IgA production_Homo sapiens_hsa046720.04817061
137Cysteine and methionine metabolism_Homo sapiens_hsa002700.04774412
138Tight junction_Homo sapiens_hsa045300.04363973
139Collecting duct acid secretion_Homo sapiens_hsa049660.03849626
140Cardiac muscle contraction_Homo sapiens_hsa042600.03545739
141Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.02630431
142Osteoclast differentiation_Homo sapiens_hsa043800.01464463

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »