CCDC14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.47358413
2mitotic metaphase plate congression (GO:0007080)5.41505601
3mitotic chromosome condensation (GO:0007076)5.01461439
4metaphase plate congression (GO:0051310)4.82527020
5attachment of spindle microtubules to kinetochore (GO:0008608)4.77175549
6protein localization to chromosome, centromeric region (GO:0071459)4.71610855
7DNA replication initiation (GO:0006270)4.59163389
8CENP-A containing nucleosome assembly (GO:0034080)4.48504272
9chromatin remodeling at centromere (GO:0031055)4.47575282
10mitotic nuclear envelope disassembly (GO:0007077)4.42149601
11nuclear pore organization (GO:0006999)4.37120733
12kinetochore organization (GO:0051383)4.36436854
13mitotic sister chromatid segregation (GO:0000070)4.35784193
14mitotic sister chromatid cohesion (GO:0007064)4.35322152
15nuclear pore complex assembly (GO:0051292)4.32198563
16establishment of chromosome localization (GO:0051303)4.31122417
17meiotic chromosome segregation (GO:0045132)4.27178543
18DNA unwinding involved in DNA replication (GO:0006268)4.17543166
19DNA replication-independent nucleosome organization (GO:0034724)4.15262302
20DNA replication-independent nucleosome assembly (GO:0006336)4.15262302
21nuclear envelope disassembly (GO:0051081)4.14038099
22membrane disassembly (GO:0030397)4.14038099
23DNA strand elongation involved in DNA replication (GO:0006271)4.11772052
24histone exchange (GO:0043486)4.08640792
25DNA replication checkpoint (GO:0000076)4.07679329
26sister chromatid segregation (GO:0000819)3.99768695
27DNA replication-dependent nucleosome assembly (GO:0006335)3.99227233
28DNA replication-dependent nucleosome organization (GO:0034723)3.99227233
29regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.94657465
30regulation of spindle organization (GO:0090224)3.94187342
31regulation of DNA endoreduplication (GO:0032875)3.93229873
32telomere maintenance via semi-conservative replication (GO:0032201)3.90948710
33DNA strand elongation (GO:0022616)3.90792266
34kinetochore assembly (GO:0051382)3.86627485
35telomere maintenance via recombination (GO:0000722)3.83825850
36regulation of sister chromatid cohesion (GO:0007063)3.80781193
37protein K6-linked ubiquitination (GO:0085020)3.76988099
38mitotic recombination (GO:0006312)3.75095534
39DNA topological change (GO:0006265)3.74108682
40spindle checkpoint (GO:0031577)3.73379491
41positive regulation of chromosome segregation (GO:0051984)3.73295920
42protein localization to chromosome (GO:0034502)3.72920481
43piRNA metabolic process (GO:0034587)3.70187833
44regulation of centriole replication (GO:0046599)3.67976576
45chromosome segregation (GO:0007059)3.65590380
46negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.61789279
47regulation of chromosome segregation (GO:0051983)3.61454868
48regulation of mitotic spindle organization (GO:0060236)3.60994599
49regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.57183348
50regulation of centrosome duplication (GO:0010824)3.57137131
51regulation of centrosome cycle (GO:0046605)3.55421475
52chromatin assembly or disassembly (GO:0006333)3.54679408
53negative regulation of chromosome segregation (GO:0051985)3.54140609
54histone H2A monoubiquitination (GO:0035518)3.52484801
55maturation of 5.8S rRNA (GO:0000460)3.51857976
56pre-miRNA processing (GO:0031054)3.51178785
57negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.50261145
58negative regulation of sister chromatid segregation (GO:0033046)3.50261145
59negative regulation of mitotic sister chromatid separation (GO:2000816)3.50261145
60negative regulation of mitotic sister chromatid segregation (GO:0033048)3.50261145
61positive regulation of mitotic sister chromatid separation (GO:1901970)3.49994527
62positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.49994527
63positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.49994527
64regulation of mitotic metaphase/anaphase transition (GO:0030071)3.48229061
65spindle assembly checkpoint (GO:0071173)3.46981058
66replication fork processing (GO:0031297)3.45544585
67centriole replication (GO:0007099)3.44306318
68mitotic spindle checkpoint (GO:0071174)3.44091799
69negative regulation of histone methylation (GO:0031061)3.42525829
70telomere maintenance via telomere lengthening (GO:0010833)3.41322048
71mitotic spindle assembly checkpoint (GO:0007094)3.40414647
72nucleotide-excision repair, DNA gap filling (GO:0006297)3.39216861
73regulation of mitotic sister chromatid separation (GO:0010965)3.35399383
74regulation of mitotic sister chromatid segregation (GO:0033047)3.35399383
75regulation of sister chromatid segregation (GO:0033045)3.35399383
76folic acid-containing compound biosynthetic process (GO:0009396)3.34485564
77regulation of histone H3-K9 methylation (GO:0051570)3.33812881
78ribosome assembly (GO:0042255)3.29902785
79mismatch repair (GO:0006298)3.28991810
80ATP-dependent chromatin remodeling (GO:0043044)3.28338861
81regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.27317323
82pore complex assembly (GO:0046931)3.26993431
83nucleobase biosynthetic process (GO:0046112)3.25474283
84nuclear envelope organization (GO:0006998)3.22174366
85negative regulation of meiosis (GO:0045835)3.22064527
86DNA duplex unwinding (GO:0032508)3.21492722
87meiotic cell cycle (GO:0051321)3.20398549
88DNA geometric change (GO:0032392)3.20073430
89negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.16349028
90maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.15770331
91sister chromatid cohesion (GO:0007062)3.14898034
92negative regulation of translation, ncRNA-mediated (GO:0040033)3.14225085
93regulation of translation, ncRNA-mediated (GO:0045974)3.14225085
94negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.14225085
95negative regulation of DNA repair (GO:0045738)3.14013987
96resolution of meiotic recombination intermediates (GO:0000712)3.13067952
97chromosome condensation (GO:0030261)3.08768229
98regulation of double-strand break repair via homologous recombination (GO:0010569)3.07724827
99gene silencing by RNA (GO:0031047)3.06215970
100somatic diversification of immune receptors via somatic mutation (GO:0002566)3.05860734
101somatic hypermutation of immunoglobulin genes (GO:0016446)3.05860734
102regulation of telomere maintenance via telomerase (GO:0032210)3.04223042
103purine nucleobase biosynthetic process (GO:0009113)3.01416294
104DNA conformation change (GO:0071103)3.00021444
105IMP metabolic process (GO:0046040)2.98687615
106IMP biosynthetic process (GO:0006188)2.97367402
107positive regulation of cell cycle checkpoint (GO:1901978)2.94947883
108non-recombinational repair (GO:0000726)2.93186365
109double-strand break repair via nonhomologous end joining (GO:0006303)2.93186365
110microtubule depolymerization (GO:0007019)2.93018047
111negative regulation of DNA-dependent DNA replication (GO:2000104)2.92537385
112mitotic cell cycle (GO:0000278)2.91029771
113chromosome organization (GO:0051276)2.90278403
114heterochromatin organization (GO:0070828)2.89899496
115monoubiquitinated protein deubiquitination (GO:0035520)2.89692507
116DNA double-strand break processing (GO:0000729)2.85657432
117DNA ligation (GO:0006266)2.82737106
118paraxial mesoderm development (GO:0048339)2.80886448
119embryonic foregut morphogenesis (GO:0048617)2.77363679
120microtubule anchoring (GO:0034453)2.75540111
121artery development (GO:0060840)2.72085037
122centrosome organization (GO:0051297)2.71846462
123notochord development (GO:0030903)2.71621310
124limb bud formation (GO:0060174)2.70749050
125regulation of RNA export from nucleus (GO:0046831)2.70666229
126microtubule organizing center organization (GO:0031023)2.69810024
127histone H3-K9 methylation (GO:0051567)2.66743840
128centriole assembly (GO:0098534)2.64695461
129DNA packaging (GO:0006323)2.63385232
130centrosome duplication (GO:0051298)2.62510705
131mitotic G2/M transition checkpoint (GO:0044818)2.62234658
132mRNA splice site selection (GO:0006376)2.56600618
133microtubule polymerization or depolymerization (GO:0031109)2.54738167
134DNA synthesis involved in DNA repair (GO:0000731)2.53452367
135regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.51912156
136intra-S DNA damage checkpoint (GO:0031573)2.50604907
137negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.49518668
138regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.47927933
139regulation of mitotic spindle checkpoint (GO:1903504)2.47927933
140negative regulation of mRNA processing (GO:0050686)2.45241503
141regulation of non-canonical Wnt signaling pathway (GO:2000050)2.45132376
142presynaptic membrane assembly (GO:0097105)2.43093790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.75825760
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.47031455
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.10396012
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.65184434
5AR_21909140_ChIP-Seq_LNCAP_Human2.90109885
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.88425290
7FUS_26573619_Chip-Seq_HEK293_Human2.71744669
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.62144286
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.57987156
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.57361671
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.54714688
12E2F1_21310950_ChIP-Seq_MCF-7_Human2.52462159
13EWS_26573619_Chip-Seq_HEK293_Human2.44929115
14* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.38769654
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.37428476
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.35071710
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34944346
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.32660645
19EST1_17652178_ChIP-ChIP_JURKAT_Human2.23183004
20MYC_18358816_ChIP-ChIP_MESCs_Mouse2.21815738
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21756019
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.18912657
23* MYCN_18555785_ChIP-Seq_MESCs_Mouse2.08325002
24IGF1R_20145208_ChIP-Seq_DFB_Human2.06729604
25* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.06626464
26GABP_17652178_ChIP-ChIP_JURKAT_Human2.04307652
27EGR1_19374776_ChIP-ChIP_THP-1_Human2.04225821
28GBX2_23144817_ChIP-Seq_PC3_Human2.03703219
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.01248135
30TAF15_26573619_Chip-Seq_HEK293_Human2.00729224
31E2F7_22180533_ChIP-Seq_HELA_Human10.9433800
32ETS1_20019798_ChIP-Seq_JURKAT_Human1.92240969
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91236085
34JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.88702307
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.86679181
36CREB1_15753290_ChIP-ChIP_HEK293T_Human1.81272840
37XRN2_22483619_ChIP-Seq_HELA_Human1.81008579
38HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80209658
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.77245833
40VDR_23849224_ChIP-Seq_CD4+_Human1.76631766
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.76151465
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73322546
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73045144
44E2F1_18555785_ChIP-Seq_MESCs_Mouse1.69424359
45POU5F1_16153702_ChIP-ChIP_HESCs_Human1.68007776
46RBPJ_22232070_ChIP-Seq_NCS_Mouse1.67138719
47ZNF274_21170338_ChIP-Seq_K562_Hela1.64501213
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63377067
49* GABP_19822575_ChIP-Seq_HepG2_Human1.60608207
50FOXP3_21729870_ChIP-Seq_TREG_Human1.58891469
51PIAS1_25552417_ChIP-Seq_VCAP_Human1.58544574
52WT1_19549856_ChIP-ChIP_CCG9911_Human1.58496663
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58257891
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.57819593
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.55006082
56TTF2_22483619_ChIP-Seq_HELA_Human1.53016500
57DCP1A_22483619_ChIP-Seq_HELA_Human1.52618502
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50504836
59P300_19829295_ChIP-Seq_ESCs_Human1.49703443
60SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.48263579
61GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46231246
62CIITA_25753668_ChIP-Seq_RAJI_Human1.43827190
63VDR_22108803_ChIP-Seq_LS180_Human1.43437234
64KDM5A_27292631_Chip-Seq_BREAST_Human1.41489764
65MYC_22102868_ChIP-Seq_BL_Human1.41324255
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.39343284
67POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38907260
68TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38907260
69ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38884919
70PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38158626
71TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.36979429
72FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.36519747
73HOXB4_20404135_ChIP-ChIP_EML_Mouse1.35484081
74CBX2_27304074_Chip-Seq_ESCs_Mouse1.33773413
75SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.32541244
76SOX9_26525672_Chip-Seq_HEART_Mouse1.32320539
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32297531
78SMAD4_21799915_ChIP-Seq_A2780_Human1.31559661
79POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.31441846
80THAP11_20581084_ChIP-Seq_MESCs_Mouse1.31065240
81* STAT3_23295773_ChIP-Seq_U87_Human1.30374946
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30135369
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.29892579
84ELK1_19687146_ChIP-ChIP_HELA_Human1.29424879
85NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.28885502
86* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27877570
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25945208
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.24908791
89E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.24674637
90RNF2_27304074_Chip-Seq_NSC_Mouse1.24105388
91HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.22931924
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22309197
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21899642
94CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21815038
95SOX2_16153702_ChIP-ChIP_HESCs_Human1.19735699
96PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18566585
97* NANOG_21062744_ChIP-ChIP_HESCs_Human1.18470458
98RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17844324
99MYC_18940864_ChIP-ChIP_HL60_Human1.15474533
100TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14331414
101ER_23166858_ChIP-Seq_MCF-7_Human1.13385218
102FOXM1_26456572_ChIP-Seq_MCF-7_Human1.12882969
103SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.12504904
104FLI1_27457419_Chip-Seq_LIVER_Mouse1.12092730
105AR_21572438_ChIP-Seq_LNCaP_Human1.12083966
106CBP_20019798_ChIP-Seq_JUKART_Human1.11948987
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11948987
108CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11069685
109TBX3_20139965_ChIP-Seq_ESCs_Mouse1.10509400
110TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09787179
111TCF4_23295773_ChIP-Seq_U87_Human1.09767964
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09093765
113STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.08662790
114HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08518203
115STAT3_1855785_ChIP-Seq_MESCs_Mouse1.07173950
116NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.06422276
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06144662
118SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05264528
119PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.05066897
120RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04581509
121SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04518146
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04262335
123E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03845002
124DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03408515
125TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02044290
126TP53_16413492_ChIP-PET_HCT116_Human1.01153502
127ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.00995010
128TCF3_18692474_ChIP-Seq_MESCs_Mouse1.00341275
129SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99102998
130SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.98548570
131TFEB_21752829_ChIP-Seq_HELA_Human0.98440840
132ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98329641
133SRF_21415370_ChIP-Seq_HL-1_Mouse0.97968799
134YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97061408
135NANOG_18555785_Chip-Seq_ESCs_Mouse0.96658189
136NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96434557
137TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.95699381
138NANOG_16153702_ChIP-ChIP_HESCs_Human0.95680597
139TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95198727
140RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94553581
141TCF4_18268006_ChIP-ChIP_LS174T_Human0.93896339
142KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93554418
143TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93460153
144* RUNX2_22187159_ChIP-Seq_PCA_Human0.92252732
145CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92247822
146ISL1_27105846_Chip-Seq_CPCs_Mouse0.91828050
147DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.91098184
148YY1_21170310_ChIP-Seq_MESCs_Mouse0.90500841
149* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.89674693
150AR_25329375_ChIP-Seq_VCAP_Human0.88813311
151POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.88799479
152HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87284232
153IRF1_19129219_ChIP-ChIP_H3396_Human0.85869497
154MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.85086471
155ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.84701360
156CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.84381521
157EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.84168329
158ELF1_17652178_ChIP-ChIP_JURKAT_Human0.83891425
159PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82974658
160CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82490788
161E2F1_18555785_Chip-Seq_ESCs_Mouse0.82185904
162EZH2_27294783_Chip-Seq_NPCs_Mouse0.81775775
163KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.79572557
164NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.78683400
165KAP1_22055183_ChIP-Seq_ESCs_Mouse0.78259709
166NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.77088924
167NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.74559098
168CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.74327039
169FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.72695446
170BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.71712071
171KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.71426027
172GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.68034125
173* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.67051936
174CHD1_26751641_Chip-Seq_LNCaP_Human0.66570018
175* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.66534613

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.16471277
2MP0003693_abnormal_embryo_hatching4.88447886
3MP0003111_abnormal_nucleus_morphology4.40686024
4MP0008057_abnormal_DNA_replication4.07244892
5MP0003077_abnormal_cell_cycle4.04525213
6MP0004957_abnormal_blastocyst_morpholog4.00116413
7MP0008877_abnormal_DNA_methylation3.17205608
8MP0008058_abnormal_DNA_repair3.15574369
9MP0008007_abnormal_cellular_replicative2.87622868
10MP0003718_maternal_effect2.80680304
11MP0008932_abnormal_embryonic_tissue2.49064284
12MP0003123_paternal_imprinting2.34690964
13MP0001730_embryonic_growth_arrest2.28665347
14MP0000350_abnormal_cell_proliferation2.25065906
15MP0010352_gastrointestinal_tract_polyps2.14072719
16MP0002009_preneoplasia2.05714382
17MP0003121_genomic_imprinting1.95403202
18MP0010307_abnormal_tumor_latency1.89264209
19MP0002697_abnormal_eye_size1.87415767
20MP0002653_abnormal_ependyma_morphology1.87378925
21MP0001672_abnormal_embryogenesis/_devel1.87198449
22MP0005380_embryogenesis_phenotype1.87198449
23MP0002210_abnormal_sex_determination1.85766579
24MP0002396_abnormal_hematopoietic_system1.83734851
25MP0001929_abnormal_gametogenesis1.82214121
26MP0003890_abnormal_embryonic-extraembry1.81680572
27MP0002085_abnormal_embryonic_tissue1.81451785
28MP0001697_abnormal_embryo_size1.80301688
29MP0002084_abnormal_developmental_patter1.71625164
30MP0000569_abnormal_digit_pigmentation1.69757982
31MP0003786_premature_aging1.69619645
32MP0000653_abnormal_sex_gland1.60615445
33MP0010030_abnormal_orbit_morphology1.60093491
34MP0003984_embryonic_growth_retardation1.57852017
35MP0001119_abnormal_female_reproductive1.55270332
36MP0000778_abnormal_nervous_system1.55041865
37MP0002088_abnormal_embryonic_growth/wei1.54207763
38MP0003941_abnormal_skin_development1.52047454
39MP0006292_abnormal_olfactory_placode1.51265861
40MP0002233_abnormal_nose_morphology1.48574782
41MP0001145_abnormal_male_reproductive1.48110167
42MP0002080_prenatal_lethality1.46855231
43MP0000537_abnormal_urethra_morphology1.45361418
44MP0000490_abnormal_crypts_of1.41296473
45MP0002086_abnormal_extraembryonic_tissu1.40623874
46MP0003385_abnormal_body_wall1.40254391
47MP0003136_yellow_coat_color1.40244228
48MP0002102_abnormal_ear_morphology1.39142728
49MP0002234_abnormal_pharynx_morphology1.36712850
50MP0004808_abnormal_hematopoietic_stem1.36311109
51MP0003937_abnormal_limbs/digits/tail_de1.34711934
52MP0002019_abnormal_tumor_incidence1.33957535
53MP0000313_abnormal_cell_death1.31789882
54MP0003787_abnormal_imprinting1.30728428
55MP0001299_abnormal_eye_distance/1.28728117
56MP0003699_abnormal_female_reproductive1.28579682
57MP0002751_abnormal_autonomic_nervous1.28176568
58MP0000383_abnormal_hair_follicle1.28137594
59MP0004197_abnormal_fetal_growth/weight/1.27920581
60MP0003283_abnormal_digestive_organ1.25473846
61MP0005076_abnormal_cell_differentiation1.23726375
62MP0009250_abnormal_appendicular_skeleto1.21390351
63MP0000631_abnormal_neuroendocrine_gland1.20846129
64MP0003567_abnormal_fetal_cardiomyocyte1.17727450
65MP0003942_abnormal_urinary_system1.16660482
66MP0000049_abnormal_middle_ear1.16004976
67MP0005171_absent_coat_pigmentation1.15495199
68MP0003115_abnormal_respiratory_system1.11803257
69MP0005187_abnormal_penis_morphology1.11634664
70MP0001293_anophthalmia1.11390582
71MP0009053_abnormal_anal_canal1.09311340
72MP0005503_abnormal_tendon_morphology1.08386765
73MP0008995_early_reproductive_senescence1.07083175
74MP0003315_abnormal_perineum_morphology1.05937344
75MP0000534_abnormal_ureter_morphology1.04781296
76MP0002109_abnormal_limb_morphology1.02659991
77MP0005395_other_phenotype1.01692501
78MP0009384_cardiac_valve_regurgitation1.00465343
79MP0003938_abnormal_ear_development1.00335010
80MP0002161_abnormal_fertility/fecundity1.00163083
81MP0003119_abnormal_digestive_system0.99260620
82MP0002249_abnormal_larynx_morphology0.98977286
83MP0005248_abnormal_Harderian_gland0.97928431
84MP0000427_abnormal_hair_cycle0.97606585
85MP0004264_abnormal_extraembryonic_tissu0.97195155
86MP0005391_vision/eye_phenotype0.97115375
87MP0003698_abnormal_male_reproductive0.96611663
88MP0000647_abnormal_sebaceous_gland0.94399077
89MP0003943_abnormal_hepatobiliary_system0.94058543
90MP0002081_perinatal_lethality0.93396771
91MP0005451_abnormal_body_composition0.92108924
92MP0001915_intracranial_hemorrhage0.91201436
93MP0002184_abnormal_innervation0.88124836
94MP0001545_abnormal_hematopoietic_system0.87496809
95MP0005397_hematopoietic_system_phenotyp0.87496809
96MP0003763_abnormal_thymus_physiology0.86899031
97MP0003705_abnormal_hypodermis_morpholog0.86862226
98MP0010678_abnormal_skin_adnexa0.86097528
99MP0003880_abnormal_central_pattern0.84338446
100MP0000703_abnormal_thymus_morphology0.83326235
101MP0004133_heterotaxia0.83061175
102MP0001177_atelectasis0.82574953
103MP0005389_reproductive_system_phenotype0.81816000
104MP0002111_abnormal_tail_morphology0.80389759
105MP0008789_abnormal_olfactory_epithelium0.80375836
106MP0005384_cellular_phenotype0.79930648
107MP0005621_abnormal_cell_physiology0.79365981
108MP0002160_abnormal_reproductive_system0.79334098
109MP0002152_abnormal_brain_morphology0.79301237
110MP0001286_abnormal_eye_development0.77353965
111MP0000432_abnormal_head_morphology0.77344126
112MP0000566_synostosis0.76593689
113MP0003935_abnormal_craniofacial_develop0.74445906
114MP0001919_abnormal_reproductive_system0.72945193
115MP0005023_abnormal_wound_healing0.71348544
116MP0003755_abnormal_palate_morphology0.69935555
117MP0001849_ear_inflammation0.69805314
118MP0009672_abnormal_birth_weight0.69496496
119MP0003861_abnormal_nervous_system0.69035829
120MP0009703_decreased_birth_body0.67855560
121MP0006072_abnormal_retinal_apoptosis0.67609866
122MP0002938_white_spotting0.66323852
123MP0009697_abnormal_copulation0.66196865
124MP0002932_abnormal_joint_morphology0.65300707
125MP0002925_abnormal_cardiovascular_devel0.65119631
126MP0002398_abnormal_bone_marrow0.64969596
127MP0002114_abnormal_axial_skeleton0.64276322
128MP0003221_abnormal_cardiomyocyte_apopto0.62841806
129MP0003566_abnormal_cell_adhesion0.61287142
130MP0000689_abnormal_spleen_morphology0.61047454
131MP0002722_abnormal_immune_system0.60759867
132MP0005408_hypopigmentation0.59559741
133MP0002092_abnormal_eye_morphology0.58484924
134MP0003806_abnormal_nucleotide_metabolis0.57880928
135MP0002282_abnormal_trachea_morphology0.57675934
136MP0000358_abnormal_cell_content/0.57475769
137MP0003646_muscle_fatigue0.57004944
138MP0002116_abnormal_craniofacial_bone0.54652723
139MP0000428_abnormal_craniofacial_morphol0.54160097

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.51749016
2Chromsome breakage (HP:0040012)5.23673169
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.92214860
4Breast hypoplasia (HP:0003187)4.01277100
5Patellar aplasia (HP:0006443)3.80162387
6Abnormality of chromosome stability (HP:0003220)3.77089417
7Abnormality of the labia minora (HP:0012880)3.62367532
8Medulloblastoma (HP:0002885)3.52452695
9Aplasia/Hypoplasia of the patella (HP:0006498)3.46205651
10Meckel diverticulum (HP:0002245)3.38272955
11Aplasia/Hypoplasia of the uvula (HP:0010293)3.34945528
12Abnormality of the preputium (HP:0100587)3.32122494
13Aplasia/Hypoplasia of the sternum (HP:0006714)3.28672899
14Rhabdomyosarcoma (HP:0002859)3.24772430
15Supernumerary spleens (HP:0009799)3.23948152
16Abnormality of the ileum (HP:0001549)3.22090906
17Ependymoma (HP:0002888)3.20225589
18Myelodysplasia (HP:0002863)3.11024456
19Ectopic kidney (HP:0000086)3.04061546
20Duodenal stenosis (HP:0100867)3.04042991
21Small intestinal stenosis (HP:0012848)3.04042991
22Impulsivity (HP:0100710)3.02672470
23Male infertility (HP:0003251)3.01066366
24Selective tooth agenesis (HP:0001592)2.90973534
25Absent radius (HP:0003974)2.83571793
26Sloping forehead (HP:0000340)2.83352046
27Papillary thyroid carcinoma (HP:0002895)2.77208970
28Colon cancer (HP:0003003)2.76936973
29Facial hemangioma (HP:0000329)2.70425487
30Absent forearm bone (HP:0003953)2.68620309
31Aplasia involving forearm bones (HP:0009822)2.68620309
32Premature ovarian failure (HP:0008209)2.66055914
33Nephroblastoma (Wilms tumor) (HP:0002667)2.62598255
34Oral leukoplakia (HP:0002745)2.57510071
35Embryonal renal neoplasm (HP:0011794)2.50203616
36Abnormality of the duodenum (HP:0002246)2.49335127
37Reticulocytopenia (HP:0001896)2.49308599
38Shawl scrotum (HP:0000049)2.48729390
39Aplastic anemia (HP:0001915)2.48207289
40Abnormality of the carotid arteries (HP:0005344)2.47023045
41Neoplasm of striated muscle (HP:0009728)2.45582527
42Abnormal lung lobation (HP:0002101)2.45537637
43Volvulus (HP:0002580)2.42877382
44Agnosia (HP:0010524)2.39220642
45Bone marrow hypocellularity (HP:0005528)2.37215194
46Increased nuchal translucency (HP:0010880)2.37181484
47High anterior hairline (HP:0009890)2.37175592
48Cafe-au-lait spot (HP:0000957)2.33700545
49Abnormality of the renal collecting system (HP:0004742)2.28957691
50Short thumb (HP:0009778)2.28235115
51Absent thumb (HP:0009777)2.28210919
52Acute myeloid leukemia (HP:0004808)2.26879729
53Abnormality of the fingertips (HP:0001211)2.26352905
54Neoplasm of the oral cavity (HP:0100649)2.25802677
55Lip pit (HP:0100267)2.24715445
56Clubbing of toes (HP:0100760)2.23574472
57Astrocytoma (HP:0009592)2.23125959
58Abnormality of the astrocytes (HP:0100707)2.23125959
59Intestinal atresia (HP:0011100)2.19356958
60Midline defect of the nose (HP:0004122)2.18743542
61Sandal gap (HP:0001852)2.17650126
62Rib fusion (HP:0000902)2.16941281
63Abnormality of cochlea (HP:0000375)2.15782638
64Duplicated collecting system (HP:0000081)2.14090230
65Tubulointerstitial nephritis (HP:0001970)2.11550447
66Breast aplasia (HP:0100783)2.09669761
67Horseshoe kidney (HP:0000085)2.08720827
68Carpal bone hypoplasia (HP:0001498)2.07770011
69Degeneration of anterior horn cells (HP:0002398)2.06080817
70Abnormality of the anterior horn cell (HP:0006802)2.06080817
71Cutaneous finger syndactyly (HP:0010554)2.04550530
72Sparse lateral eyebrow (HP:0005338)2.02243263
73Atresia of the external auditory canal (HP:0000413)2.01028501
74Esophageal atresia (HP:0002032)2.00447836
75Capillary hemangiomas (HP:0005306)2.00026094
76Abnormality of abdominal situs (HP:0011620)1.98420291
77Abdominal situs inversus (HP:0003363)1.98420291
78Aplasia/Hypoplasia of the breasts (HP:0010311)1.96887916
79Secondary amenorrhea (HP:0000869)1.96353543
80Tracheoesophageal fistula (HP:0002575)1.93403087
81Glioma (HP:0009733)1.92591927
82Bifid tongue (HP:0010297)1.92314438
83Oligodactyly (HP:0012165)1.92265234
84Gastrointestinal atresia (HP:0002589)1.92108959
85Neoplasm of the pancreas (HP:0002894)1.91776096
86High pitched voice (HP:0001620)1.90472509
87Abnormality of chromosome segregation (HP:0002916)1.88980360
88Abnormality of the ischium (HP:0003174)1.88961670
89Duplication of thumb phalanx (HP:0009942)1.88453238
90Cortical dysplasia (HP:0002539)1.86780920
91Arteriovenous malformation (HP:0100026)1.85728839
92Aqueductal stenosis (HP:0002410)1.85278398
93Neoplasm of the colon (HP:0100273)1.84363317
94Nephronophthisis (HP:0000090)1.84103630
95Cutaneous syndactyly (HP:0012725)1.83360983
96Abnormality of DNA repair (HP:0003254)1.82933481
97Deviation of the thumb (HP:0009603)1.82921000
98Triphalangeal thumb (HP:0001199)1.82900743
99Anophthalmia (HP:0000528)1.81472573
100Bilateral microphthalmos (HP:0007633)1.81325166
101Prominent nose (HP:0000448)1.80994962
102Oligodactyly (hands) (HP:0001180)1.80784251
103Acute lymphatic leukemia (HP:0006721)1.80585013
104Short 4th metacarpal (HP:0010044)1.80437430
105Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.80437430
106Slender long bone (HP:0003100)1.79574639
107Hypoplastic labia majora (HP:0000059)1.79299892
108Biliary tract neoplasm (HP:0100574)1.78578138
109Overlapping toe (HP:0001845)1.78402155
110Adrenal hypoplasia (HP:0000835)1.77585692
111Chronic hepatic failure (HP:0100626)1.77462409
11211 pairs of ribs (HP:0000878)1.77206930
113Missing ribs (HP:0000921)1.77001493
114Astigmatism (HP:0000483)1.76749748
115Microretrognathia (HP:0000308)1.76084929
116Heterotopia (HP:0002282)1.75909480
117Preaxial foot polydactyly (HP:0001841)1.75362793
118Malignant gastrointestinal tract tumors (HP:0006749)1.75151668
119Gastrointestinal carcinoma (HP:0002672)1.75151668
120Basal cell carcinoma (HP:0002671)1.74173130
121Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.73930991
122Abnormality of the renal medulla (HP:0100957)1.72334297
123Vaginal atresia (HP:0000148)1.67006562
124Genital tract atresia (HP:0001827)1.66978100
125Truncal obesity (HP:0001956)1.66505598
126Drooling (HP:0002307)1.66378119
127Deep philtrum (HP:0002002)1.65648122
128Hypoplastic ischia (HP:0003175)1.60714545
129Abnormal number of incisors (HP:0011064)1.58720279
130Abnormality of midbrain morphology (HP:0002418)1.58522428
131Molar tooth sign on MRI (HP:0002419)1.58522428
132Preaxial hand polydactyly (HP:0001177)1.58353297
133Renal hypoplasia (HP:0000089)1.58286331
134Pancreatic fibrosis (HP:0100732)1.58046316
135Postaxial foot polydactyly (HP:0001830)1.57662922
136Hypoplastic iliac wings (HP:0002866)1.57320142
137True hermaphroditism (HP:0010459)1.56977455
138Short middle phalanx of finger (HP:0005819)1.56515703
139Hyperventilation (HP:0002883)1.56283590
140Abnormality of the 4th metacarpal (HP:0010012)1.56160235
141Poor coordination (HP:0002370)1.56157406
142Obsessive-compulsive behavior (HP:0000722)1.55621348
143Hepatoblastoma (HP:0002884)1.54968350
144Large earlobe (HP:0009748)1.54061393
145Cystic hygroma (HP:0000476)1.53692200
146Pancreatic cysts (HP:0001737)1.53431371
147Protruding tongue (HP:0010808)1.52722714
148Morphological abnormality of the middle ear (HP:0008609)1.50733670

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.52736789
2TTK3.91964152
3PLK43.53373626
4WEE13.46982524
5NEK23.10542390
6BUB12.94542335
7EEF2K2.74877110
8PNCK2.62254682
9CDK122.42692925
10NEK12.37654405
11PLK12.29080634
12FRK2.24080976
13LATS12.23154301
14CASK2.17824058
15ACVR1B2.04943255
16CHEK22.03401361
17CAMK1G1.99119524
18MAP3K61.97376973
19EIF2AK11.95022443
20STK38L1.89543587
21BRAF1.87888546
22STK101.85809822
23MAP3K101.85629910
24FGFR21.85171700
25ATR1.84948737
26RPS6KB21.76840282
27AURKB1.76456797
28CDK71.74398460
29SRPK11.71992668
30BRSK21.70361370
31AKT31.69397710
32MAP3K81.61825424
33LATS21.58633809
34MAP3K41.55525838
35PLK31.51184513
36CAMK1D1.48075983
37CHEK11.45411584
38BMPR1B1.42654902
39CDK81.39169167
40MELK1.36040470
41TAF11.35545333
42MOS1.33954802
43STK31.26636252
44WNK31.26157596
45TAOK31.24819267
46ATM1.21725424
47AURKA1.20908489
48BCR1.20353728
49CDK41.19736210
50VRK11.15317756
51RAF11.14175072
52CDK31.14022719
53MKNK11.13956828
54PASK1.13411042
55TGFBR11.11922956
56STK391.09516552
57TNIK1.07686412
58BRSK11.04218434
59TSSK61.03383100
60KSR21.02488535
61DYRK31.00432825
62PDGFRA0.97361005
63ERBB40.96890835
64ERBB30.96763316
65RPS6KA40.95306219
66MAPKAPK30.94871945
67CDK20.92797444
68BRD40.92149141
69PBK0.90679326
70FGFR10.89863447
71EPHA20.85947840
72MARK10.84797314
73STK40.84412675
74KSR10.80026581
75MAP3K90.79679783
76CDK10.78874667
77SCYL20.78699453
78PLK20.76674373
79EIF2AK30.70699865
80MKNK20.70141793
81DYRK20.69923938
82CDK60.67335964
83ZAK0.67204740
84TESK20.66229193
85MAP2K70.66155878
86CDK90.64952670
87INSRR0.64924799
88PKN20.64592463
89PIM10.63844115
90EIF2AK20.62764516
91EPHA40.61459786
92YES10.61158700
93DYRK1A0.59386281
94MAP3K130.55780837
95MAP4K20.52787112
96EPHB20.52085603
97PAK40.51649465
98BMPR20.51001915
99NUAK10.50737395
100FLT30.49073652
101TRIM280.48753526
102MET0.48223606
103MTOR0.48046583
104WNK40.46284281
105NTRK20.46010333
106TYRO30.44531486
107NEK90.44366077
108CSNK1D0.43787698
109ERBB20.43647152
110PAK10.43279584
111PDK40.42376793
112PDK30.42376793
113TEC0.42137652
114WNK10.42086625
115PIK3CA0.41822223
116CSNK2A10.41690737
117CSNK2A20.40147399
118PRKD30.40034229
119PRKDC0.38917566
120CCNB10.38234282
121MAPKAPK50.36952303
122CSNK1A1L0.35924361
123ARAF0.33773159
124MAP4K10.33373610
125MAPK140.33225494
126AKT10.32728393
127ALK0.32334227
128PRKCI0.32162853
129CSNK1E0.31882541
130MAPK110.29995083
131MUSK0.28753884
132CSNK1G10.27646668
133TRPM70.27558852
134LRRK20.25568597
135GSK3B0.25318797
136CSNK1G30.24555255
137MAPK130.23861496
138MAPK10.23782489
139MAP3K50.23108021
140NLK0.21900795
141AKT20.21619054
142TAOK10.19758149

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.91988457
2Mismatch repair_Homo sapiens_hsa034304.38058787
3Homologous recombination_Homo sapiens_hsa034403.71375708
4Cell cycle_Homo sapiens_hsa041103.68368271
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.37990404
6Base excision repair_Homo sapiens_hsa034103.28785290
7RNA transport_Homo sapiens_hsa030133.18954828
8Fanconi anemia pathway_Homo sapiens_hsa034603.14048116
9Nucleotide excision repair_Homo sapiens_hsa034202.93714654
10Non-homologous end-joining_Homo sapiens_hsa034502.83003879
11RNA degradation_Homo sapiens_hsa030182.78180149
12Spliceosome_Homo sapiens_hsa030402.77066967
13Basal transcription factors_Homo sapiens_hsa030222.60383544
14RNA polymerase_Homo sapiens_hsa030202.45223251
15One carbon pool by folate_Homo sapiens_hsa006702.29923705
16Pyrimidine metabolism_Homo sapiens_hsa002402.02430692
17p53 signaling pathway_Homo sapiens_hsa041151.99446867
18mRNA surveillance pathway_Homo sapiens_hsa030151.99164789
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.93387755
20Oocyte meiosis_Homo sapiens_hsa041141.54924564
21Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.40836734
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.39427859
23Proteasome_Homo sapiens_hsa030501.38144323
24Ribosome_Homo sapiens_hsa030101.32279974
25Propanoate metabolism_Homo sapiens_hsa006401.25038442
26Purine metabolism_Homo sapiens_hsa002301.19707962
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.18892829
28MicroRNAs in cancer_Homo sapiens_hsa052061.10537215
29Taste transduction_Homo sapiens_hsa047421.09480926
30TGF-beta signaling pathway_Homo sapiens_hsa043501.05386331
31Herpes simplex infection_Homo sapiens_hsa051681.05321808
32Viral carcinogenesis_Homo sapiens_hsa052031.02790768
33Epstein-Barr virus infection_Homo sapiens_hsa051691.02656040
34ECM-receptor interaction_Homo sapiens_hsa045121.00637322
35Thyroid cancer_Homo sapiens_hsa052160.96752248
36Systemic lupus erythematosus_Homo sapiens_hsa053220.94654123
37HTLV-I infection_Homo sapiens_hsa051660.94462654
38Axon guidance_Homo sapiens_hsa043600.90542835
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90248542
40Colorectal cancer_Homo sapiens_hsa052100.89061521
41Nicotine addiction_Homo sapiens_hsa050330.86778306
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83957818
43Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81992617
44Hippo signaling pathway_Homo sapiens_hsa043900.81149050
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78162030
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.77109452
47Small cell lung cancer_Homo sapiens_hsa052220.75085579
48Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.74311890
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.73362025
50Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71603829
51Protein export_Homo sapiens_hsa030600.70588222
52Vitamin B6 metabolism_Homo sapiens_hsa007500.69460723
53Dorso-ventral axis formation_Homo sapiens_hsa043200.69287983
54Choline metabolism in cancer_Homo sapiens_hsa052310.69250623
55Glioma_Homo sapiens_hsa052140.68579138
56Melanogenesis_Homo sapiens_hsa049160.68082194
57Pancreatic cancer_Homo sapiens_hsa052120.67744781
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.67711341
59Basal cell carcinoma_Homo sapiens_hsa052170.61528208
60Butanoate metabolism_Homo sapiens_hsa006500.59943480
61Adherens junction_Homo sapiens_hsa045200.58900647
62Biosynthesis of amino acids_Homo sapiens_hsa012300.58603485
63Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58123292
64Ovarian steroidogenesis_Homo sapiens_hsa049130.56286905
65Notch signaling pathway_Homo sapiens_hsa043300.56063345
66Folate biosynthesis_Homo sapiens_hsa007900.55086491
67Hepatitis B_Homo sapiens_hsa051610.54228648
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54061839
69Phototransduction_Homo sapiens_hsa047440.54028252
70Olfactory transduction_Homo sapiens_hsa047400.53698560
71Chronic myeloid leukemia_Homo sapiens_hsa052200.52726920
72ErbB signaling pathway_Homo sapiens_hsa040120.50813068
73Circadian rhythm_Homo sapiens_hsa047100.48537711
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48235224
75Protein digestion and absorption_Homo sapiens_hsa049740.48166592
76Bladder cancer_Homo sapiens_hsa052190.47662853
77Selenocompound metabolism_Homo sapiens_hsa004500.47390630
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45376485
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45198217
80Hedgehog signaling pathway_Homo sapiens_hsa043400.45110263
81Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.45026133
82Steroid biosynthesis_Homo sapiens_hsa001000.44379333
83Glutamatergic synapse_Homo sapiens_hsa047240.44371880
84Antigen processing and presentation_Homo sapiens_hsa046120.44163977
85Lysine degradation_Homo sapiens_hsa003100.43888889
86Linoleic acid metabolism_Homo sapiens_hsa005910.43769552
87PI3K-Akt signaling pathway_Homo sapiens_hsa041510.42835008
88Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.42609630
89mTOR signaling pathway_Homo sapiens_hsa041500.42143087
90Focal adhesion_Homo sapiens_hsa045100.41952423
91Pentose phosphate pathway_Homo sapiens_hsa000300.41525676
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40695731
93Pathways in cancer_Homo sapiens_hsa052000.39366271
94Endometrial cancer_Homo sapiens_hsa052130.39288504
95Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37769093
96Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.36550210
97ABC transporters_Homo sapiens_hsa020100.36480338
98Cocaine addiction_Homo sapiens_hsa050300.35965359
99Inositol phosphate metabolism_Homo sapiens_hsa005620.35717175
100Non-small cell lung cancer_Homo sapiens_hsa052230.35257314
101Long-term depression_Homo sapiens_hsa047300.35164419
102FoxO signaling pathway_Homo sapiens_hsa040680.34901561
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34840623
104Apoptosis_Homo sapiens_hsa042100.34593687
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34137488
106Gap junction_Homo sapiens_hsa045400.34030036
107Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33369709
108Wnt signaling pathway_Homo sapiens_hsa043100.33173633
109Prostate cancer_Homo sapiens_hsa052150.31903074
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.31776422
111Nitrogen metabolism_Homo sapiens_hsa009100.30862277
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29963644
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29925122
114Estrogen signaling pathway_Homo sapiens_hsa049150.29531316
115Alcoholism_Homo sapiens_hsa050340.28556954
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.28233960
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28232949
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.27800684
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.27528153
120Prolactin signaling pathway_Homo sapiens_hsa049170.27093400
121Shigellosis_Homo sapiens_hsa051310.26350685
122HIF-1 signaling pathway_Homo sapiens_hsa040660.25793281
123Acute myeloid leukemia_Homo sapiens_hsa052210.23910253
124Measles_Homo sapiens_hsa051620.23681391
125NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22726953
126Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.22055147
127Tight junction_Homo sapiens_hsa045300.21588752
128Influenza A_Homo sapiens_hsa051640.20919296
129Legionellosis_Homo sapiens_hsa051340.20771510
130NF-kappa B signaling pathway_Homo sapiens_hsa040640.19568393
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19276597
132N-Glycan biosynthesis_Homo sapiens_hsa005100.18432781
133VEGF signaling pathway_Homo sapiens_hsa043700.18034782
134Glutathione metabolism_Homo sapiens_hsa004800.16727936
135Melanoma_Homo sapiens_hsa052180.16719600
136Jak-STAT signaling pathway_Homo sapiens_hsa046300.14873793
137Viral myocarditis_Homo sapiens_hsa054160.13737268
138Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.13318786
139Proteoglycans in cancer_Homo sapiens_hsa052050.11998654
140Cyanoamino acid metabolism_Homo sapiens_hsa004600.11950436
141Ether lipid metabolism_Homo sapiens_hsa005650.11329072
142Arachidonic acid metabolism_Homo sapiens_hsa005900.11155969
143Primary immunodeficiency_Homo sapiens_hsa053400.10762248

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