CCDC106

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.22313259
2synaptic vesicle maturation (GO:0016188)6.01035700
3synaptic vesicle exocytosis (GO:0016079)5.75853677
4locomotory exploration behavior (GO:0035641)5.65418453
5vocalization behavior (GO:0071625)5.58025885
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.56959427
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.54064948
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.53097120
9regulation of glutamate receptor signaling pathway (GO:1900449)5.22480575
10protein localization to synapse (GO:0035418)5.18638102
11regulation of synaptic vesicle exocytosis (GO:2000300)4.91104769
12regulation of synapse structural plasticity (GO:0051823)4.89702407
13glutamate secretion (GO:0014047)4.87613577
14exploration behavior (GO:0035640)4.87556237
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.75304127
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.58279086
17regulation of long-term neuronal synaptic plasticity (GO:0048169)4.54348365
18neuron cell-cell adhesion (GO:0007158)4.54235858
19regulation of neuronal synaptic plasticity (GO:0048168)4.50688396
20regulation of synaptic vesicle transport (GO:1902803)4.38899683
21neurotransmitter secretion (GO:0007269)4.34759104
22regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.26756861
23synaptic transmission, glutamatergic (GO:0035249)4.24165944
24regulation of mammary gland epithelial cell proliferation (GO:0033599)4.23492640
25neurotransmitter-gated ion channel clustering (GO:0072578)4.20512420
26glutamate receptor signaling pathway (GO:0007215)4.19811353
27establishment of mitochondrion localization (GO:0051654)4.19670350
28layer formation in cerebral cortex (GO:0021819)4.18045519
29mitochondrion transport along microtubule (GO:0047497)4.17398970
30establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.17398970
31positive regulation of synapse maturation (GO:0090129)4.15157391
32neuron-neuron synaptic transmission (GO:0007270)4.08385700
33negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.07714896
34proline biosynthetic process (GO:0006561)3.95714567
35dendritic spine morphogenesis (GO:0060997)3.90707957
36prepulse inhibition (GO:0060134)3.90600213
37positive regulation of membrane potential (GO:0045838)3.85882039
38neuronal action potential propagation (GO:0019227)3.85358574
39protein retention in ER lumen (GO:0006621)3.81687940
40synaptic vesicle endocytosis (GO:0048488)3.80942529
41long-term memory (GO:0007616)3.80347613
42long-term synaptic potentiation (GO:0060291)3.78383305
43positive regulation of synaptic transmission, GABAergic (GO:0032230)3.75185568
44membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.74604172
45regulation of synaptic plasticity (GO:0048167)3.70274729
46regulation of excitatory postsynaptic membrane potential (GO:0060079)3.69688681
47regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.66107691
48transmission of nerve impulse (GO:0019226)3.65775763
49regulation of early endosome to late endosome transport (GO:2000641)3.62918565
50positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.62846063
51positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.61505826
52cellular potassium ion homeostasis (GO:0030007)3.61361077
53regulation of dendritic spine morphogenesis (GO:0061001)3.60067244
54gamma-aminobutyric acid signaling pathway (GO:0007214)3.59052771
55behavioral defense response (GO:0002209)3.58842338
56behavioral fear response (GO:0001662)3.58842338
57protein insertion into membrane (GO:0051205)3.54321101
58proline transport (GO:0015824)3.53628697
59negative regulation of erythrocyte differentiation (GO:0045647)3.53000804
60cell-cell junction maintenance (GO:0045217)3.52873957
61neuron recognition (GO:0008038)3.52392077
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.50771828
63auditory behavior (GO:0031223)3.49129602
64postsynaptic membrane organization (GO:0001941)3.48324858
65regulation of postsynaptic membrane potential (GO:0060078)3.48250554
66gamma-aminobutyric acid transport (GO:0015812)3.47167701
67neurotransmitter transport (GO:0006836)3.47147269
68striatum development (GO:0021756)3.43626138
69negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.40357586
70positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.39072821
71neuromuscular process controlling balance (GO:0050885)3.38767404
72negative regulation of cell size (GO:0045792)3.38005158
73sodium ion export (GO:0071436)3.36972299
74regulation of neurotransmitter secretion (GO:0046928)3.35754333
75G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.34123953
76maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.31229574
77regulation of vesicle fusion (GO:0031338)3.30768744
78activation of protein kinase A activity (GO:0034199)3.28675797
79dopamine receptor signaling pathway (GO:0007212)3.28047398
80positive regulation of neurotransmitter transport (GO:0051590)3.27184852
81fear response (GO:0042596)3.26820849
82peptidyl-arginine omega-N-methylation (GO:0035247)3.26572205
83innervation (GO:0060384)3.26193766
84cell migration in hindbrain (GO:0021535)3.25281689
85regulation of neurotransmitter transport (GO:0051588)3.24072646
86positive regulation of dendritic spine morphogenesis (GO:0061003)3.24021197
87regulation of neurotransmitter levels (GO:0001505)3.21992323
88membrane depolarization during action potential (GO:0086010)3.21069433
89synaptic transmission, dopaminergic (GO:0001963)3.20288273
90learning (GO:0007612)3.19656216
91response to auditory stimulus (GO:0010996)3.19643480
92adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.19428921
93activation of MAPKKK activity (GO:0000185)3.18979811
94regulation of synapse maturation (GO:0090128)3.17797126
95regulation of female receptivity (GO:0045924)3.17648355
96regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.16040000
97regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.16040000
98negative regulation of synaptic transmission, GABAergic (GO:0032229)3.15632069
99cell communication by electrical coupling (GO:0010644)3.14751881
100regulation of glutamate secretion (GO:0014048)3.14189909
101axonal fasciculation (GO:0007413)3.13104788
102response to histamine (GO:0034776)3.12462486
103positive regulation of synaptic transmission (GO:0050806)3.12439326
104dendrite morphogenesis (GO:0048813)3.12373110
105membrane depolarization (GO:0051899)3.12047239
106adenosine receptor signaling pathway (GO:0001973)3.11541940
107positive regulation of neurotransmitter secretion (GO:0001956)3.10706819
108G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.10384721
109cerebellar Purkinje cell differentiation (GO:0021702)3.10076866
110membrane hyperpolarization (GO:0060081)3.09780494
111cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.08361156
112positive regulation of dendritic spine development (GO:0060999)3.08057816
113deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.06762398
114retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.05967044
115behavioral response to cocaine (GO:0048148)3.05181194
116dendritic spine organization (GO:0097061)3.04750116
117regulation of synaptic transmission (GO:0050804)3.03904792
118neuronal ion channel clustering (GO:0045161)3.03419727
119synapse assembly (GO:0007416)3.02598846
120response to acidic pH (GO:0010447)2.97885553
121protein localization to endosome (GO:0036010)2.96067430
122respiratory system process (GO:0003016)2.87571185
123ribosomal small subunit biogenesis (GO:0042274)2.87363435
124tooth mineralization (GO:0034505)2.87141080
125protein maturation by protein folding (GO:0022417)2.86586035
126cerebellar Purkinje cell layer development (GO:0021680)2.85299278
127regulation of ARF protein signal transduction (GO:0032012)2.85206705
128negative regulation of microtubule polymerization (GO:0031115)2.84245473
129creatine metabolic process (GO:0006600)2.82827199
130regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.81045262
131cerebellar granule cell differentiation (GO:0021707)2.79736598
132histone arginine methylation (GO:0034969)2.74760068
133proline metabolic process (GO:0006560)2.73155588
134amino acid import (GO:0043090)2.72092182
135positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.71443569
136regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.71443569
137positive regulation of protein sumoylation (GO:0033235)2.69322684
138apoptotic process involved in morphogenesis (GO:0060561)2.65238935
139response to dietary excess (GO:0002021)2.62826159
140UV protection (GO:0009650)2.62718363
141Golgi transport vesicle coating (GO:0048200)2.62397891
142COPI coating of Golgi vesicle (GO:0048205)2.62397891
143response to parathyroid hormone (GO:0071107)2.62344314
144endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.60273642
145positive regulation of protein dephosphorylation (GO:0035307)2.58754340
146peptidyl-arginine methylation (GO:0018216)2.57795521
147peptidyl-arginine N-methylation (GO:0035246)2.57795521
148cytoskeletal anchoring at plasma membrane (GO:0007016)2.57345273
149spliceosomal tri-snRNP complex assembly (GO:0000244)2.55797041
150muscle cell fate commitment (GO:0042693)2.53422428
151adherens junction assembly (GO:0034333)2.51679789
152activation of Rac GTPase activity (GO:0032863)2.49703014
153regulation of NFAT protein import into nucleus (GO:0051532)2.48096144
154positive regulation of myotube differentiation (GO:0010831)2.46814511
155barbed-end actin filament capping (GO:0051016)2.46373868
156cell junction maintenance (GO:0034331)2.44524252
157mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.44160342
158mitochondrion localization (GO:0051646)2.43964523
159dicarboxylic acid transport (GO:0006835)2.43736684
160regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.42686352
161gluconeogenesis (GO:0006094)2.39140423
162protein targeting to plasma membrane (GO:0072661)2.37633427
163L-amino acid import (GO:0043092)2.34884326
164positive regulation of mitochondrion organization (GO:0010822)2.34144967
165regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.30886508

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.30767591
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.00906443
3GBX2_23144817_ChIP-Seq_PC3_Human3.36356643
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.15470889
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.04496814
6JARID2_20064375_ChIP-Seq_MESCs_Mouse3.04430412
7LXR_22292898_ChIP-Seq_THP-1_Human3.03466819
8REST_21632747_ChIP-Seq_MESCs_Mouse3.02719816
9* RARB_27405468_Chip-Seq_BRAIN_Mouse3.02690549
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98923435
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74149066
12RNF2_18974828_ChIP-Seq_MESCs_Mouse2.71922934
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.71922934
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.71218327
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.65415483
16VDR_21846776_ChIP-Seq_THP-1_Human2.64575485
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.60546668
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58429591
19REST_18959480_ChIP-ChIP_MESCs_Mouse2.54023609
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.52104357
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51752721
22DROSHA_22980978_ChIP-Seq_HELA_Human2.49101400
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.47333526
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.43121110
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.42423181
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.41204925
27SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40389329
28IKZF1_21737484_ChIP-ChIP_HCT116_Human2.35143409
29* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.34338963
30RNF2_27304074_Chip-Seq_ESCs_Mouse2.26715838
31EED_16625203_ChIP-ChIP_MESCs_Mouse2.24270770
32KDM2B_26808549_Chip-Seq_SUP-B15_Human2.20932687
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.20531140
34MYC_22102868_ChIP-Seq_BL_Human2.18702232
35EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.13562382
36MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.10699261
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.09744590
38ELK3_25401928_ChIP-Seq_HUVEC_Human2.09443976
39TET1_21451524_ChIP-Seq_MESCs_Mouse2.07835632
40KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.96421993
41RARG_19884340_ChIP-ChIP_MEFs_Mouse1.95900902
42P68_20966046_ChIP-Seq_HELA_Human1.95416108
43* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.93916779
44* KDM2B_26808549_Chip-Seq_DND41_Human1.93180632
45SRY_22984422_ChIP-ChIP_TESTIS_Rat1.93180585
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.87844446
47RACK7_27058665_Chip-Seq_MCF-7_Human1.87818306
48AR_21572438_ChIP-Seq_LNCaP_Human1.85795928
49SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.83161439
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.82998766
51CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.78480293
52ERG_21242973_ChIP-ChIP_JURKAT_Human1.69955142
53ZNF263_19887448_ChIP-Seq_K562_Human1.69271885
54SA1_27219007_Chip-Seq_ERYTHROID_Human1.67491214
55* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.66237568
56CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65247420
57DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.64133532
58CTCF_27219007_Chip-Seq_ERYTHROID_Human1.58663643
59ELF1_20517297_ChIP-Seq_JURKAT_Human1.58234844
60* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.55246926
61RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.53032381
62SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53024275
63SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.52434057
64SMC4_20622854_ChIP-Seq_HELA_Human1.52355038
65* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.51843160
66TAF15_26573619_Chip-Seq_HEK293_Human1.50539392
67SMAD4_21799915_ChIP-Seq_A2780_Human1.49888352
68THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49691742
69* CREB1_26743006_Chip-Seq_LNCaP_Human1.47364097
70RING1B_27294783_Chip-Seq_ESCs_Mouse1.46044522
71GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45663861
72CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.43646832
73TCF7_22412390_ChIP-Seq_EML_Mouse1.43208246
74XRN2_22483619_ChIP-Seq_HELA_Human1.40866470
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36890663
76BCL6_27268052_Chip-Seq_Bcells_Human1.36464723
77BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32438272
78RNF2_27304074_Chip-Seq_NSC_Mouse1.32097683
79KDM2B_26808549_Chip-Seq_JURKAT_Human1.31532506
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.31075908
81DNAJC2_21179169_ChIP-ChIP_NT2_Human1.31072698
82ZFP281_18757296_ChIP-ChIP_E14_Mouse1.31050872
83PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30786508
84SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.30092121
85CBX2_27304074_Chip-Seq_ESCs_Mouse1.29668285
86MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.28886535
87BCOR_27268052_Chip-Seq_Bcells_Human1.28460276
88ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28113505
89ZNF274_21170338_ChIP-Seq_K562_Hela1.27642866
90KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.26947086
91KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.26947009
92RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26772509
93CTCF_18555785_ChIP-Seq_MESCs_Mouse1.26495920
94NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.26268387
95TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26090079
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25429724
97CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.24153724
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23612548
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.22684028
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22592675
101* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.21447081
102CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.20852836
103RING1B_27294783_Chip-Seq_NPCs_Mouse1.19407071
104RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.18899391
105TP53_20018659_ChIP-ChIP_R1E_Mouse1.18353423
106MAF_26560356_Chip-Seq_TH2_Human1.17446086
107P300_19829295_ChIP-Seq_ESCs_Human1.17272035
108CTCF_26484167_Chip-Seq_Bcells_Mouse1.17063624
109MYC_18358816_ChIP-ChIP_MESCs_Mouse1.16768457
110AR_19668381_ChIP-Seq_PC3_Human1.16192450
111SA1_27219007_Chip-Seq_Bcells_Human1.15868877
112AR_25329375_ChIP-Seq_VCAP_Human1.15363970
113SMAD3_21741376_ChIP-Seq_EPCs_Human1.15057553
114* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.14111870
115* FOXP1_21924763_ChIP-Seq_HESCs_Human1.13229483
116ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12278299
117TP53_22127205_ChIP-Seq_IMR90_Human1.11026078
118RARA_24833708_ChIP-Seq_LIVER_Mouse1.10869572
119SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10071844
120NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09196338
121TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08661855
122PHF8_20622854_ChIP-Seq_HELA_Human1.08521968
123TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08163449
124STAT3_23295773_ChIP-Seq_U87_Human1.06912223
125MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06626204
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05386892
127CTCF_21964334_Chip-Seq_Bcells_Human1.05231792
128KDM2B_26808549_Chip-Seq_K562_Human1.04868993
129* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04368063
130ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04232338
131WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02789963
132KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02436791
133IGF1R_20145208_ChIP-Seq_DFB_Human1.02236077
134PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01980040
135SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.01954730
136CTCF_20526341_ChIP-Seq_ESCs_Human1.01751935
137SMAD_19615063_ChIP-ChIP_OVARY_Human1.01545269
138YY1_21170310_ChIP-Seq_MESCs_Mouse1.01031661
139E2F1_20622854_ChIP-Seq_HELA_Human1.00935636
140MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.00620632
141* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.00360714
142RARB_24833708_ChIP-Seq_LIVER_Mouse0.99697849
143VDR_24763502_ChIP-Seq_THP-1_Human0.98934190
144YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98775612
145P300_27058665_Chip-Seq_ZR-75-30cells_Human0.98747615
146CTCF_27219007_Chip-Seq_Bcells_Human0.98453581
147ETS1_21867929_ChIP-Seq_TH2_Mouse0.97729644
148CTCF_21964334_ChIP-Seq_BJAB-B_Human0.97503064
149SMAD3_21741376_ChIP-Seq_ESCs_Human0.95997331
150TET1_21490601_ChIP-Seq_MESCs_Mouse0.94389875
151TCF4_23295773_ChIP-Seq_U87_Human0.93824868
152JUN_21703547_ChIP-Seq_K562_Human0.92859485
153SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91351396
154OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90155913
155ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.89259931
156STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89210182
157POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89086798
158TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89086798
159UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88385864
160FUS_26573619_Chip-Seq_HEK293_Human0.87825208
161PRDM14_20953172_ChIP-Seq_ESCs_Human0.86927951
162TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86483262
163GATA1_26923725_Chip-Seq_HPCs_Mouse0.86217386
164CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85096173
165PIAS1_25552417_ChIP-Seq_VCAP_Human0.84911338
166OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.84657799
167RUNX2_22187159_ChIP-Seq_PCA_Human0.84627071
168GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84475277
169SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.83535118
170TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.83084160
171BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.82712641
172VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.81481364
173CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81068342

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.50953518
2MP0003880_abnormal_central_pattern4.56850812
3MP0003635_abnormal_synaptic_transmissio4.18168461
4MP0002822_catalepsy3.66819017
5MP0002063_abnormal_learning/memory/cond3.43656997
6MP0009745_abnormal_behavioral_response3.36626891
7MP0004270_analgesia3.24043776
8MP0009046_muscle_twitch3.03549020
9MP0002064_seizures3.02300818
10MP0005058_abnormal_lysosome_morphology2.90068890
11MP0001968_abnormal_touch/_nociception2.88781071
12MP0002572_abnormal_emotion/affect_behav2.83772231
13MP0005423_abnormal_somatic_nervous2.57159663
14MP0002249_abnormal_larynx_morphology2.46977498
15MP0002272_abnormal_nervous_system2.44164579
16MP0001486_abnormal_startle_reflex2.43333035
17MP0002734_abnormal_mechanical_nocicepti2.39844346
18MP0003705_abnormal_hypodermis_morpholog2.31419387
19MP0005623_abnormal_meninges_morphology2.29047936
20MP0002736_abnormal_nociception_after2.27476173
21MP0005451_abnormal_body_composition2.16102377
22MP0001501_abnormal_sleep_pattern2.14126013
23MP0001984_abnormal_olfaction2.01751258
24MP0001440_abnormal_grooming_behavior1.98140086
25MP0001529_abnormal_vocalization1.97725746
26MP0000678_abnormal_parathyroid_gland1.95353111
27MP0002184_abnormal_innervation1.91672301
28MP0002735_abnormal_chemical_nociception1.90977144
29MP0001970_abnormal_pain_threshold1.87751670
30MP0002733_abnormal_thermal_nociception1.86848466
31MP0002067_abnormal_sensory_capabilities1.85189952
32MP0002557_abnormal_social/conspecific_i1.84927540
33MP0004811_abnormal_neuron_physiology1.81714536
34MP0000778_abnormal_nervous_system1.77306215
35MP0009780_abnormal_chondrocyte_physiolo1.75716721
36MP0005386_behavior/neurological_phenoty1.75118574
37MP0004924_abnormal_behavior1.75118574
38MP0000604_amyloidosis1.69766472
39MP0005646_abnormal_pituitary_gland1.69335141
40MP0003787_abnormal_imprinting1.68848488
41MP0004858_abnormal_nervous_system1.67539949
42MP0002909_abnormal_adrenal_gland1.65157170
43MP0004510_myositis1.63468552
44MP0008260_abnormal_autophagy1.61198462
45MP0003122_maternal_imprinting1.61136526
46MP0000681_abnormal_thyroid_gland1.59929026
47MP0003172_abnormal_lysosome_physiology1.58494943
48MP0000955_abnormal_spinal_cord1.57176597
49MP0006276_abnormal_autonomic_nervous1.57148038
50MP0008569_lethality_at_weaning1.56315499
51MP0001502_abnormal_circadian_rhythm1.54973137
52MP0009840_abnormal_foam_cell1.53102555
53MP0000747_muscle_weakness1.50833416
54MP0003329_amyloid_beta_deposits1.49049881
55MP0003879_abnormal_hair_cell1.48140113
56MP0004185_abnormal_adipocyte_glucose1.48124388
57MP0002882_abnormal_neuron_morphology1.45779377
58MP0001348_abnormal_lacrimal_gland1.42921944
59MP0000759_abnormal_skeletal_muscle1.39093247
60MP0002066_abnormal_motor_capabilities/c1.38271045
61MP0009278_abnormal_bone_marrow1.35341902
62MP0005670_abnormal_white_adipose1.31729984
63MP0005645_abnormal_hypothalamus_physiol1.31728311
64MP0002089_abnormal_postnatal_growth/wei1.30904683
65MP0004142_abnormal_muscle_tone1.28507860
66MP0000750_abnormal_muscle_regeneration1.27793786
67MP0000003_abnormal_adipose_tissue1.27575526
68MP0001905_abnormal_dopamine_level1.26839465
69MP0001188_hyperpigmentation1.25748581
70MP0005551_abnormal_eye_electrophysiolog1.25500022
71MP0002152_abnormal_brain_morphology1.22605038
72MP0002653_abnormal_ependyma_morphology1.22042535
73MP0004130_abnormal_muscle_cell1.21964992
74MP0005666_abnormal_adipose_tissue1.19552676
75MP0004885_abnormal_endolymph1.19227846
76MP0001346_abnormal_lacrimal_gland1.18847354
77MP0000733_abnormal_muscle_development1.17793797
78MP0000920_abnormal_myelination1.16813282
79MP0005375_adipose_tissue_phenotype1.15521575
80MP0004233_abnormal_muscle_weight1.10607622
81MP0003633_abnormal_nervous_system1.09703810
82MP0005394_taste/olfaction_phenotype1.09619633
83MP0005499_abnormal_olfactory_system1.09619633
84MP0000631_abnormal_neuroendocrine_gland1.06062687
85MP0003690_abnormal_glial_cell1.05511598
86MP0008872_abnormal_physiological_respon1.04646103
87MP0000751_myopathy1.03768775
88MP0010030_abnormal_orbit_morphology1.03053878
89MP0001849_ear_inflammation0.99691194
90MP0002069_abnormal_eating/drinking_beha0.98000248
91MP0000049_abnormal_middle_ear0.96588172
92MP0003303_peritoneal_inflammation0.96466338
93MP0006072_abnormal_retinal_apoptosis0.96347396
94MP0003631_nervous_system_phenotype0.96222233
95MP0008961_abnormal_basal_metabolism0.94734547
96MP0004145_abnormal_muscle_electrophysio0.93990994
97MP0002090_abnormal_vision0.93310663
98MP0002229_neurodegeneration0.92384663
99MP0003942_abnormal_urinary_system0.90322970
100MP0000013_abnormal_adipose_tissue0.90237174
101MP0008877_abnormal_DNA_methylation0.89279174
102MP0003123_paternal_imprinting0.87854874
103MP0003279_aneurysm0.87353948
104MP0003283_abnormal_digestive_organ0.86401337
105MP0002752_abnormal_somatic_nervous0.84903919
106MP0004087_abnormal_muscle_fiber0.81184028
107MP0005257_abnormal_intraocular_pressure0.81170619
108MP0005076_abnormal_cell_differentiation0.80851544
109MP0004085_abnormal_heartbeat0.79228550
110MP0005167_abnormal_blood-brain_barrier0.78855674
111MP0006292_abnormal_olfactory_placode0.78382977
112MP0009379_abnormal_foot_pigmentation0.78313550
113MP0003121_genomic_imprinting0.77936156
114MP0003075_altered_response_to0.76559486
115MP0002877_abnormal_melanocyte_morpholog0.76461162
116MP0004742_abnormal_vestibular_system0.75818371
117MP0003634_abnormal_glial_cell0.75553949
118MP0001177_atelectasis0.75008677
119MP0003861_abnormal_nervous_system0.74521889
120MP0001963_abnormal_hearing_physiology0.73278974
121MP0006036_abnormal_mitochondrial_physio0.71995141
122MP0000537_abnormal_urethra_morphology0.70731335
123MP0008874_decreased_physiological_sensi0.69935471
124MP0003137_abnormal_impulse_conducting0.69751313
125MP0002638_abnormal_pupillary_reflex0.68219584
126MP0000343_altered_response_to0.67956661
127MP0005410_abnormal_fertilization0.67928334
128MP0003938_abnormal_ear_development0.65546206
129MP0001270_distended_abdomen0.65227934
130MP0005409_darkened_coat_color0.65002980
131MP0001664_abnormal_digestion0.64966445
132MP0003632_abnormal_nervous_system0.64416219
133MP0003698_abnormal_male_reproductive0.62210202
134MP0010386_abnormal_urinary_bladder0.60157047
135MP0005535_abnormal_body_temperature0.58925604
136MP0002102_abnormal_ear_morphology0.57110797
137MP0000569_abnormal_digit_pigmentation0.56882894
138MP0000534_abnormal_ureter_morphology0.56024675
139MP0004215_abnormal_myocardial_fiber0.55808714
140MP0002234_abnormal_pharynx_morphology0.54961609
141MP0010769_abnormal_survival0.54487162
142MP0001943_abnormal_respiration0.54236132
143MP0002082_postnatal_lethality0.53051361
144MP0010770_preweaning_lethality0.53051361

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.39315496
2Focal motor seizures (HP:0011153)6.66827722
3Focal seizures (HP:0007359)5.21422468
4Visual hallucinations (HP:0002367)5.10080268
5Epileptic encephalopathy (HP:0200134)4.68460204
6Febrile seizures (HP:0002373)3.98491614
7Progressive cerebellar ataxia (HP:0002073)3.95315922
8Atonic seizures (HP:0010819)3.90459565
9Absence seizures (HP:0002121)3.70546660
10Abnormality of the lower motor neuron (HP:0002366)3.66726210
11Hyperthyroidism (HP:0000836)3.61030738
12Hyperacusis (HP:0010780)3.55555255
13Generalized tonic-clonic seizures (HP:0002069)3.43938699
14Ankle clonus (HP:0011448)3.35204404
15Truncus arteriosus (HP:0001660)3.31635710
16Dialeptic seizures (HP:0011146)3.31615059
17Impaired vibration sensation in the lower limbs (HP:0002166)3.31337130
18Mutism (HP:0002300)3.17348793
19Supranuclear gaze palsy (HP:0000605)3.10609527
20Depression (HP:0000716)3.09168624
21Action tremor (HP:0002345)3.07427405
22Broad-based gait (HP:0002136)3.07384806
23Achilles tendon contracture (HP:0001771)2.96250434
24Dysdiadochokinesis (HP:0002075)2.96048813
25Abnormal eating behavior (HP:0100738)2.95253009
26Broad distal phalanx of finger (HP:0009836)2.94668476
27Anxiety (HP:0000739)2.94056740
28Poor eye contact (HP:0000817)2.93614209
29Torticollis (HP:0000473)2.91150930
30Gaze-evoked nystagmus (HP:0000640)2.80862519
31Urinary bladder sphincter dysfunction (HP:0002839)2.77191786
32Amblyopia (HP:0000646)2.73588126
33Myopathic facies (HP:0002058)2.71435226
34Focal dystonia (HP:0004373)2.70937204
35Limb dystonia (HP:0002451)2.66643579
36Abnormal social behavior (HP:0012433)2.66622919
37Impaired social interactions (HP:0000735)2.66622919
38Truncal ataxia (HP:0002078)2.66240574
39Dysmetria (HP:0001310)2.63248151
40Urinary urgency (HP:0000012)2.62176054
41Stridor (HP:0010307)2.61843402
42Distal upper limb amyotrophy (HP:0007149)2.59723632
43Upper limb amyotrophy (HP:0009129)2.59723632
44Abnormality of the Achilles tendon (HP:0005109)2.59164964
45Turricephaly (HP:0000262)2.58579723
46Hemiparesis (HP:0001269)2.52885603
47Polyphagia (HP:0002591)2.51353181
48Postural instability (HP:0002172)2.51107665
49Craniofacial dystonia (HP:0012179)2.50427645
50Hyperventilation (HP:0002883)2.49995794
51Ragged-red muscle fibers (HP:0003200)2.46770653
52Drooling (HP:0002307)2.45638970
53Excessive salivation (HP:0003781)2.45638970
54Cholecystitis (HP:0001082)2.43274488
55Abnormal gallbladder physiology (HP:0012438)2.43274488
56Spastic gait (HP:0002064)2.42485211
57Long palpebral fissure (HP:0000637)2.41442878
58Annular pancreas (HP:0001734)2.40781529
59Double outlet right ventricle (HP:0001719)2.40304162
60Congenital malformation of the right heart (HP:0011723)2.40304162
61Amyotrophic lateral sclerosis (HP:0007354)2.40239506
62Gait imbalance (HP:0002141)2.39845313
63Epileptiform EEG discharges (HP:0011182)2.37380724
64Centrally nucleated skeletal muscle fibers (HP:0003687)2.35831655
65Abnormality of the aortic arch (HP:0012303)2.34795926
66Pointed chin (HP:0000307)2.33714225
67Impaired smooth pursuit (HP:0007772)2.33638456
68Diminished motivation (HP:0000745)2.30193821
69Axonal loss (HP:0003447)2.30136994
70Genetic anticipation (HP:0003743)2.29781062
71Bradykinesia (HP:0002067)2.29505100
72EEG with generalized epileptiform discharges (HP:0011198)2.28873561
73Bowel incontinence (HP:0002607)2.27088268
74Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.26240005
75Hypertensive crisis (HP:0100735)2.24697821
76Hypercortisolism (HP:0001578)2.24330516
77Apathy (HP:0000741)2.23979134
78Distal lower limb amyotrophy (HP:0008944)2.23265991
79Megalencephaly (HP:0001355)2.22585273
80Bulbar palsy (HP:0001283)2.22364189
81Hand muscle atrophy (HP:0009130)2.22080591
82Papilledema (HP:0001085)2.21267748
83Diplopia (HP:0000651)2.21198435
84Abnormality of binocular vision (HP:0011514)2.21198435
85Vertebral compression fractures (HP:0002953)2.20590776
86Progressive inability to walk (HP:0002505)2.19806056
87Abnormal large intestine physiology (HP:0012700)2.19685088
88Hypsarrhythmia (HP:0002521)2.16294315
89Lower limb amyotrophy (HP:0007210)2.15257622
90Fetal akinesia sequence (HP:0001989)2.14926947
91Abnormality of ocular smooth pursuit (HP:0000617)2.13156459
92Absent speech (HP:0001344)2.12976794
93Peripheral hypomyelination (HP:0007182)2.12935731
94Stereotypic behavior (HP:0000733)2.12095132
95Ventricular fibrillation (HP:0001663)2.11991325
96Incomplete penetrance (HP:0003829)2.10908719
97Specific learning disability (HP:0001328)2.09451757
98Cerebral inclusion bodies (HP:0100314)2.09172231
99Central scotoma (HP:0000603)2.08812586
100Increased variability in muscle fiber diameter (HP:0003557)2.08074460
101Aplasia/Hypoplasia of the sacrum (HP:0008517)2.07199978
102Hypoplastic left heart (HP:0004383)2.06955180
103Elfin facies (HP:0004428)2.05857870
104Atelectasis (HP:0100750)2.04941089
105Delusions (HP:0000746)2.03730602
106Upper motor neuron abnormality (HP:0002127)2.03184798
107Impaired vibratory sensation (HP:0002495)2.02444740
108Scanning speech (HP:0002168)2.01574851
109Overriding aorta (HP:0002623)2.00820946
110Pheochromocytoma (HP:0002666)2.00293408
111Hemiplegia (HP:0002301)2.00257215
112Hypoventilation (HP:0002791)1.99601324
113Abnormality of glycolipid metabolism (HP:0010969)1.98990663
114Abnormality of liposaccharide metabolism (HP:0010968)1.98990663
115Abnormality of glycosphingolipid metabolism (HP:0004343)1.98990663
116Unilateral renal agenesis (HP:0000122)1.98901634
117Lower limb muscle weakness (HP:0007340)1.97933492
118Poor suck (HP:0002033)1.97793467
119Congenital primary aphakia (HP:0007707)1.97450246
120Status epilepticus (HP:0002133)1.97109545
121Deep palmar crease (HP:0006191)1.96424336
122Obstructive sleep apnea (HP:0002870)1.95913217
123Exercise-induced myalgia (HP:0003738)1.95130780
124Increased cerebral lipofuscin (HP:0011813)1.92681622
125Athetosis (HP:0002305)1.92130603
126Ankyloglossia (HP:0010296)1.92004060
127Sleep apnea (HP:0010535)1.91700117
128Hypoplasia of the brainstem (HP:0002365)1.91364358
129Aplasia/Hypoplasia of the brainstem (HP:0007362)1.91364358
130Generalized hypotonia (HP:0001290)1.90486928
131Medial flaring of the eyebrow (HP:0010747)1.90386956
132Resting tremor (HP:0002322)1.90121853
133Neuronal loss in central nervous system (HP:0002529)1.89817114
134Neurofibrillary tangles (HP:0002185)1.88601089
135Dementia (HP:0000726)1.87667940
136Dysostosis multiplex (HP:0000943)1.87591397
137Neoplasm of the heart (HP:0100544)1.86718213
138Shoulder girdle muscle weakness (HP:0003547)1.86680275
139Insomnia (HP:0100785)1.85523807
140Dysmetric saccades (HP:0000641)1.84895603
141Renal duplication (HP:0000075)1.84594660
142Unsteady gait (HP:0002317)1.83826273
143Failure to thrive in infancy (HP:0001531)1.83507857
144Hyperparathyroidism (HP:0000843)1.83390171
145Cholelithiasis (HP:0001081)1.82620914
146Tetraplegia (HP:0002445)1.80778277
147Ulnar bowing (HP:0003031)1.80373378
148Generalized myoclonic seizures (HP:0002123)1.80122372
149Nuclear cataract (HP:0100018)1.79884691
150Growth hormone excess (HP:0000845)1.79597122
151Abnormality of the thoracic spine (HP:0100711)1.79394467
152Neoplasm of the peripheral nervous system (HP:0100007)1.79025764
153Neuroendocrine neoplasm (HP:0100634)1.79019356
154Clonus (HP:0002169)1.78669659
155Testicular atrophy (HP:0000029)1.78300672
156Inability to walk (HP:0002540)1.78232502
157Abnormality of skeletal muscle fiber size (HP:0012084)1.78021046
158Distal lower limb muscle weakness (HP:0009053)1.77764191
159Abnormality of macular pigmentation (HP:0008002)1.77352675
160Abnormal connection of the cardiac segments (HP:0011545)1.76588410
161Abnormal ventriculo-arterial connection (HP:0011563)1.76588410
162Transposition of the great arteries (HP:0001669)1.76588410
163Nephrogenic diabetes insipidus (HP:0009806)1.75590240
164Patellar dislocation (HP:0002999)1.75282697
165Foot dorsiflexor weakness (HP:0009027)1.74493823
166Gastrointestinal stroma tumor (HP:0100723)1.74282134
167Abnormality of the gallbladder (HP:0005264)1.74081562
168Distal sensory impairment (HP:0002936)1.73367434
169Rapidly progressive (HP:0003678)1.72586284
170Polygenic inheritance (HP:0010982)1.72029321
171Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.71689208
172Prolonged neonatal jaundice (HP:0006579)1.69354361
173Abnormality of the tricuspid valve (HP:0001702)1.69213577
174Protrusio acetabuli (HP:0003179)1.68136294
175Increased neuronal autofluorescent lipopigment (HP:0002074)1.67423406

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.68160425
2MAP3K94.67293525
3NTRK34.19226769
4TRIB34.00468993
5SMG13.46867165
6MARK13.12491979
7NME22.91337057
8ICK2.89423318
9KSR22.74712837
10MAP3K42.72328729
11MINK12.70420208
12ARAF2.60410686
13PRKD32.39997226
14PAK62.38089595
15MAP3K112.25090150
16KSR12.24864053
17NTRK22.21719648
18IRAK32.20914151
19DAPK22.17797989
20SIK12.17703073
21CASK2.12038115
22MAP2K72.08667143
23ERN12.04040085
24EEF2K2.00168233
25MAP3K121.94201889
26TESK11.94045205
27DAPK11.61156604
28PLK21.53896233
29CAMKK11.50120630
30MAP3K131.47910181
31CDK51.45455060
32TESK21.44657451
33MAP2K41.41778562
34RAF11.38434400
35MAPK131.35248624
36PRPF4B1.35197197
37PIM21.35163792
38RIPK41.32396645
39BCKDK1.29869048
40LATS21.23240639
41GRK51.20555569
42SIK21.20308213
43TAOK11.19990289
44PRKCG1.19097655
45CAMK1D1.18460501
46PHKG11.17609356
47PHKG21.17609356
48NTRK11.16740789
49LIMK11.15003235
50VRK21.14823951
51MAP3K21.12608215
52BRAF1.11291635
53RIPK11.10196984
54CDK191.10002388
55FES1.09658300
56NEK11.06491775
57CDK181.05920709
58STK381.04751929
59PNCK1.03723968
60CDK141.02978665
61TNIK1.01590717
62CDK151.01526948
63TYRO30.98818066
64IRAK20.95901984
65MAPK120.95252995
66PRKD20.91261956
67CDK11A0.90035976
68UHMK10.89356082
69CAMK2A0.88960921
70PTK2B0.87963462
71DYRK1A0.80877369
72NME10.80435938
73CAMKK20.79116692
74SIK30.77094258
75TTN0.75060668
76ABL20.74690700
77MAP2K30.74661407
78LMTK20.73815911
79SGK4940.73733793
80SGK2230.73733793
81DYRK1B0.72722405
82PKN20.71080346
83CDK120.69452179
84AURKA0.69436479
85MARK20.68460424
86MAPK110.68420608
87MAP3K10.67405295
88CAMK10.66055244
89TBK10.65524419
90PAK30.65378850
91TNK20.65255235
92CAMK2B0.64026701
93MTOR0.63996030
94STK110.63039947
95AKT20.61838674
96KDR0.60428325
97PRKCH0.58694422
98CAMK1G0.58266090
99CSNK1G30.58261721
100SGK10.57444976
101SGK20.57004494
102BMPR20.56504237
103DDR20.55178617
104CDK80.55011911
105CSNK1G20.53814486
106MAP3K100.52700782
107CAMK40.51347089
108RET0.50740526
109PDGFRA0.50721896
110MAP2K10.48653484
111HIPK20.48393898
112ALK0.48184936
113RPS6KC10.47964100
114RPS6KL10.47964100
115MAPK40.47550802
116PRKCZ0.47285218
117CSNK1A1L0.47251460
118RPS6KA20.45768521
119PDPK10.45006757
120PDK10.44876395
121DAPK30.44467128
122MOS0.43113328
123WNK30.42813784
124MAPK100.42172657
125RPS6KA30.42090107
126ILK0.41934254
127STK160.41632014
128CCNB10.41621928
129BRSK10.41596849
130MAPKAPK50.41384420
131MAP4K10.41193600
132PDK30.40821445
133PDK40.40821445
134PAK10.40438579
135MAP3K80.40105541
136PINK10.39544488
137SGK30.39544195
138PRKCE0.39040564
139PKN10.38851828
140CDC42BPA0.38218913
141MAP3K60.35046782
142BCR0.34049810
143CAMK2G0.33225662
144CAMK2D0.32980580
145DYRK20.30741026
146FYN0.30122679
147OXSR10.29730840
148FER0.29442854
149TAOK20.28568675
150ERBB30.28237845

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.92399999
2Synaptic vesicle cycle_Homo sapiens_hsa047213.66832880
3Sulfur relay system_Homo sapiens_hsa041223.13011447
4Olfactory transduction_Homo sapiens_hsa047403.03013029
5GABAergic synapse_Homo sapiens_hsa047272.80827826
6Circadian entrainment_Homo sapiens_hsa047132.77300279
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.72224768
8Long-term potentiation_Homo sapiens_hsa047202.64943244
9Morphine addiction_Homo sapiens_hsa050322.63786534
10Amphetamine addiction_Homo sapiens_hsa050312.60561413
11Glutamatergic synapse_Homo sapiens_hsa047242.43205735
12Dopaminergic synapse_Homo sapiens_hsa047282.27348016
132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.24060370
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.21668773
15Vitamin B6 metabolism_Homo sapiens_hsa007502.09668595
16Salivary secretion_Homo sapiens_hsa049701.97946440
17Insulin secretion_Homo sapiens_hsa049111.95495467
18Cholinergic synapse_Homo sapiens_hsa047251.95405981
19Cocaine addiction_Homo sapiens_hsa050301.92589478
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.87200768
21Other glycan degradation_Homo sapiens_hsa005111.85706120
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.80284387
23Biosynthesis of amino acids_Homo sapiens_hsa012301.80218859
24Collecting duct acid secretion_Homo sapiens_hsa049661.78947269
25Renin secretion_Homo sapiens_hsa049241.77091716
26Oxytocin signaling pathway_Homo sapiens_hsa049211.71781572
27Gastric acid secretion_Homo sapiens_hsa049711.69983629
28Taste transduction_Homo sapiens_hsa047421.69482660
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67045053
30Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.66829348
31Long-term depression_Homo sapiens_hsa047301.65637963
32Serotonergic synapse_Homo sapiens_hsa047261.64085193
33Calcium signaling pathway_Homo sapiens_hsa040201.59525981
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.55057884
35Gap junction_Homo sapiens_hsa045401.51108597
36GnRH signaling pathway_Homo sapiens_hsa049121.49774962
37Notch signaling pathway_Homo sapiens_hsa043301.46617660
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.46450182
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.37680060
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.35077841
41Cardiac muscle contraction_Homo sapiens_hsa042601.26527662
42cAMP signaling pathway_Homo sapiens_hsa040241.24848332
43Arginine and proline metabolism_Homo sapiens_hsa003301.24053782
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.24040933
45Pentose phosphate pathway_Homo sapiens_hsa000301.22714388
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19212344
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18450655
48Vibrio cholerae infection_Homo sapiens_hsa051101.17283682
49Estrogen signaling pathway_Homo sapiens_hsa049151.16678111
50Bladder cancer_Homo sapiens_hsa052191.15317325
51Axon guidance_Homo sapiens_hsa043601.14308520
52Glioma_Homo sapiens_hsa052141.14190915
53Fructose and mannose metabolism_Homo sapiens_hsa000511.10681616
54Oocyte meiosis_Homo sapiens_hsa041141.10565226
55Melanogenesis_Homo sapiens_hsa049161.08060923
56Carbon metabolism_Homo sapiens_hsa012001.07858255
57Lysosome_Homo sapiens_hsa041421.06872117
58B cell receptor signaling pathway_Homo sapiens_hsa046621.06389222
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.06119326
60Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04834779
61cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04806324
62Type II diabetes mellitus_Homo sapiens_hsa049301.02269776
63ErbB signaling pathway_Homo sapiens_hsa040120.97804753
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96950072
65AMPK signaling pathway_Homo sapiens_hsa041520.96321539
66Chronic myeloid leukemia_Homo sapiens_hsa052200.95896720
67Phototransduction_Homo sapiens_hsa047440.94397499
68Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93946396
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93360864
70Galactose metabolism_Homo sapiens_hsa000520.90852482
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.90183002
72Alcoholism_Homo sapiens_hsa050340.85693501
73Ribosome_Homo sapiens_hsa030100.85085629
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.78252565
75MAPK signaling pathway_Homo sapiens_hsa040100.73920748
76Acute myeloid leukemia_Homo sapiens_hsa052210.73753178
77Dilated cardiomyopathy_Homo sapiens_hsa054140.72529057
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.70754844
79Base excision repair_Homo sapiens_hsa034100.70102994
80Choline metabolism in cancer_Homo sapiens_hsa052310.69084019
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67116220
82VEGF signaling pathway_Homo sapiens_hsa043700.66814187
83Glucagon signaling pathway_Homo sapiens_hsa049220.66256431
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62985508
85Thyroid hormone synthesis_Homo sapiens_hsa049180.62637059
86Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62533910
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61256458
88Dorso-ventral axis formation_Homo sapiens_hsa043200.60918765
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.60609635
90Alzheimers disease_Homo sapiens_hsa050100.60551334
91Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58678948
92Salmonella infection_Homo sapiens_hsa051320.57542289
93Ras signaling pathway_Homo sapiens_hsa040140.57534131
94Parkinsons disease_Homo sapiens_hsa050120.55128287
95Rap1 signaling pathway_Homo sapiens_hsa040150.55118288
96Non-small cell lung cancer_Homo sapiens_hsa052230.54734898
97Endometrial cancer_Homo sapiens_hsa052130.54559940
98mTOR signaling pathway_Homo sapiens_hsa041500.53986014
99Pancreatic secretion_Homo sapiens_hsa049720.53412178
100Pyruvate metabolism_Homo sapiens_hsa006200.52360441
101Oxidative phosphorylation_Homo sapiens_hsa001900.52202022
102Toll-like receptor signaling pathway_Homo sapiens_hsa046200.52026796
103Circadian rhythm_Homo sapiens_hsa047100.51000583
104Renal cell carcinoma_Homo sapiens_hsa052110.50857685
105Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50733116
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50183155
107Pancreatic cancer_Homo sapiens_hsa052120.50143348
108Phenylalanine metabolism_Homo sapiens_hsa003600.50094842
109Prion diseases_Homo sapiens_hsa050200.49951573
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48895627
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48398554
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.47678628
113Endocytosis_Homo sapiens_hsa041440.46758758
114Colorectal cancer_Homo sapiens_hsa052100.46584829
115Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46110037
116Wnt signaling pathway_Homo sapiens_hsa043100.45521974
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43929373
118Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41545772
119Huntingtons disease_Homo sapiens_hsa050160.41535100
120Sphingolipid signaling pathway_Homo sapiens_hsa040710.40530572
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38894827
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38538942
123Insulin signaling pathway_Homo sapiens_hsa049100.38472426
124Type I diabetes mellitus_Homo sapiens_hsa049400.37774203
125Inositol phosphate metabolism_Homo sapiens_hsa005620.35851168
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33483576
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32803550
128Melanoma_Homo sapiens_hsa052180.31859705
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31066687
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.30745952
131Hedgehog signaling pathway_Homo sapiens_hsa043400.27588775
132Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26211145
133Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.20928652
134Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.20342220
135Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.20127069

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