CCAR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.82040676
2nuclear pore organization (GO:0006999)4.67004820
3kinetochore organization (GO:0051383)4.56632685
4nuclear pore complex assembly (GO:0051292)4.41827410
5protein localization to kinetochore (GO:0034501)4.39968201
6metaphase plate congression (GO:0051310)4.31799472
7DNA unwinding involved in DNA replication (GO:0006268)4.26518130
8CENP-A containing nucleosome assembly (GO:0034080)4.22108010
9mitotic sister chromatid cohesion (GO:0007064)4.12014832
10chromatin remodeling at centromere (GO:0031055)4.09905591
11regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.03521103
12DNA replication-independent nucleosome organization (GO:0034724)3.91893163
13DNA replication-independent nucleosome assembly (GO:0006336)3.91893163
14kinetochore assembly (GO:0051382)3.91461669
15positive regulation of mitotic sister chromatid separation (GO:1901970)3.89357775
16positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.89357775
17positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.89357775
18positive regulation of chromosome segregation (GO:0051984)3.82817608
19mitotic chromosome condensation (GO:0007076)3.80146113
20protein localization to chromosome, centromeric region (GO:0071459)3.79131102
21establishment of chromosome localization (GO:0051303)3.77828386
22protein prenylation (GO:0018342)3.77498008
23prenylation (GO:0097354)3.77498008
24histone exchange (GO:0043486)3.73057926
25mitotic nuclear envelope disassembly (GO:0007077)3.69102319
26DNA replication initiation (GO:0006270)3.68201021
27replication fork processing (GO:0031297)3.62476811
28DNA replication checkpoint (GO:0000076)3.61772864
29pore complex assembly (GO:0046931)3.60826991
30regulation of spindle organization (GO:0090224)3.58656009
31attachment of spindle microtubules to kinetochore (GO:0008608)3.56951578
32sister chromatid segregation (GO:0000819)3.51400242
33spindle checkpoint (GO:0031577)3.49765993
34regulation of RNA export from nucleus (GO:0046831)3.49716754
35DNA strand elongation involved in DNA replication (GO:0006271)3.47270417
36regulation of mitotic metaphase/anaphase transition (GO:0030071)3.43968948
37mitotic recombination (GO:0006312)3.41746349
38mitotic sister chromatid segregation (GO:0000070)3.41645607
39nuclear envelope disassembly (GO:0051081)3.41109733
40membrane disassembly (GO:0030397)3.41109733
41DNA double-strand break processing (GO:0000729)3.40836732
42regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.36888757
43purine nucleobase biosynthetic process (GO:0009113)3.35455962
44mitotic spindle checkpoint (GO:0071174)3.35453813
45nucleobase biosynthetic process (GO:0046112)3.34213435
46telomere maintenance via recombination (GO:0000722)3.33744999
47ATP-dependent chromatin remodeling (GO:0043044)3.33173686
48formation of translation preinitiation complex (GO:0001731)3.32775390
49DNA strand elongation (GO:0022616)3.32594949
50centriole replication (GO:0007099)3.30279018
51DNA topological change (GO:0006265)3.30149350
52regulation of sister chromatid segregation (GO:0033045)3.28101492
53regulation of mitotic sister chromatid separation (GO:0010965)3.28101492
54regulation of mitotic sister chromatid segregation (GO:0033047)3.28101492
55spindle assembly checkpoint (GO:0071173)3.27224544
56negative regulation of mitotic sister chromatid separation (GO:2000816)3.26452243
57negative regulation of mitotic sister chromatid segregation (GO:0033048)3.26452243
58negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.26452243
59negative regulation of sister chromatid segregation (GO:0033046)3.26452243
60regulation of DNA damage checkpoint (GO:2000001)3.26080173
61regulation of chromosome segregation (GO:0051983)3.26030998
62regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.25795276
63telomere maintenance via telomerase (GO:0007004)3.25518396
64negative regulation of chromosome segregation (GO:0051985)3.24306925
65histone-serine phosphorylation (GO:0035404)3.21965654
66mitotic spindle assembly checkpoint (GO:0007094)3.21035484
67telomere maintenance via semi-conservative replication (GO:0032201)3.19989754
68negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.17804840
69regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16258299
70regulation of sister chromatid cohesion (GO:0007063)3.15081276
71meiotic chromosome segregation (GO:0045132)3.14348172
72negative regulation of DNA recombination (GO:0045910)3.12306657
73regulation of mitotic spindle organization (GO:0060236)3.07721768
74viral mRNA export from host cell nucleus (GO:0046784)3.06937764
75negative regulation of mRNA processing (GO:0050686)3.06084331
76chromatin assembly or disassembly (GO:0006333)3.03859852
77somatic diversification of immune receptors via somatic mutation (GO:0002566)3.03039652
78somatic hypermutation of immunoglobulin genes (GO:0016446)3.03039652
79negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.00649898
80DNA duplex unwinding (GO:0032508)2.99844717
81* RNA splicing, via transesterification reactions (GO:0000375)2.99299331
82DNA geometric change (GO:0032392)2.99089614
83regulation of centrosome cycle (GO:0046605)2.98991467
84DNA replication-dependent nucleosome assembly (GO:0006335)2.97089608
85DNA replication-dependent nucleosome organization (GO:0034723)2.97089608
86* mRNA splicing, via spliceosome (GO:0000398)2.96849540
87* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.96849540
88IMP biosynthetic process (GO:0006188)2.96457217
89histone mRNA metabolic process (GO:0008334)2.95828514
90regulation of centriole replication (GO:0046599)2.94874134
91resolution of meiotic recombination intermediates (GO:0000712)2.94422311
92protein localization to chromosome (GO:0034502)2.93206388
93spliceosomal complex assembly (GO:0000245)2.92726042
94microtubule depolymerization (GO:0007019)2.92633017
95regulation of DNA endoreduplication (GO:0032875)2.92304961
96negative regulation of RNA splicing (GO:0033119)2.92118461
97mitotic G2/M transition checkpoint (GO:0044818)2.92049280
98pre-miRNA processing (GO:0031054)2.90763678
99chromosome segregation (GO:0007059)2.90112602
100regulation of nuclear cell cycle DNA replication (GO:0033262)2.89450500
101ribosome assembly (GO:0042255)2.88925514
102nucleotide-excision repair, DNA gap filling (GO:0006297)2.88909972
103negative regulation of DNA-dependent DNA replication (GO:2000104)2.87287707
104spliceosomal snRNP assembly (GO:0000387)2.85543938
105regulation of centrosome duplication (GO:0010824)2.84483992
106negative regulation of mRNA metabolic process (GO:1903312)2.82336190
107recombinational repair (GO:0000725)2.81837480
108ribosome biogenesis (GO:0042254)2.81494939
109telomere maintenance via telomere lengthening (GO:0010833)2.81154616
110double-strand break repair via homologous recombination (GO:0000724)2.80805627
111negative regulation of DNA repair (GO:0045738)2.79771898
112monoubiquitinated protein deubiquitination (GO:0035520)2.79438032
113establishment of integrated proviral latency (GO:0075713)2.78720744
114DNA ligation (GO:0006266)2.77291341
115DNA conformation change (GO:0071103)2.76358805
116maturation of SSU-rRNA (GO:0030490)2.75336286
117termination of RNA polymerase II transcription (GO:0006369)2.74999438
118histone H2A acetylation (GO:0043968)2.74912095
119regulation of helicase activity (GO:0051095)2.74820428
120sister chromatid cohesion (GO:0007062)2.74496286
121RNA export from nucleus (GO:0006405)2.74308248
122maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.73977596
123regulation of mitotic spindle checkpoint (GO:1903504)2.73885369
124regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.73885369
125synapsis (GO:0007129)2.70633095
126double-strand break repair via nonhomologous end joining (GO:0006303)2.68182645
127non-recombinational repair (GO:0000726)2.68182645
128pseudouridine synthesis (GO:0001522)2.66487931
129negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.65887241

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.50784813
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.90636225
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.41512507
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.87051005
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.69070987
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.16401080
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.05218891
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.87627914
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.85611642
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.67076352
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.63068286
12AR_21909140_ChIP-Seq_LNCAP_Human2.58881043
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.56898169
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.51122331
15TP63_19390658_ChIP-ChIP_HaCaT_Human2.50185490
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.48649326
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.42261222
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.40452356
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.38329390
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.38008979
21E2F1_21310950_ChIP-Seq_MCF-7_Human2.37042619
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35786467
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.34247264
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.28415130
25VDR_23849224_ChIP-Seq_CD4+_Human2.27708410
26JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.24850319
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.23669300
28ELK1_19687146_ChIP-ChIP_HELA_Human2.23318603
29MYC_18358816_ChIP-ChIP_MESCs_Mouse2.23220714
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.21555912
31* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.19596801
32VDR_22108803_ChIP-Seq_LS180_Human2.18113307
33SALL1_21062744_ChIP-ChIP_HESCs_Human2.17361754
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.08466123
35XRN2_22483619_ChIP-Seq_HELA_Human2.07404160
36FOXP3_21729870_ChIP-Seq_TREG_Human2.04064681
37* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.97921193
38ZNF274_21170338_ChIP-Seq_K562_Hela1.87824474
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.82556042
40CIITA_25753668_ChIP-Seq_RAJI_Human1.81607807
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.80664102
42MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.79955076
43DCP1A_22483619_ChIP-Seq_HELA_Human1.77407605
44TTF2_22483619_ChIP-Seq_HELA_Human1.73710581
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.72992907
46PADI4_21655091_ChIP-ChIP_MCF-7_Human1.71849952
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68748715
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.67200053
49GABP_19822575_ChIP-Seq_HepG2_Human1.64402211
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63041130
51* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.60637361
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60595532
53IGF1R_20145208_ChIP-Seq_DFB_Human1.56769625
54TAF15_26573619_Chip-Seq_HEK293_Human1.50235424
55KDM5A_27292631_Chip-Seq_BREAST_Human1.49126509
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45152222
57NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44359919
58* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42599048
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36260759
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.29362427
61ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27967399
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.27515241
63KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27130474
64KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27130474
65KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27130474
66SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.25883350
67* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23673796
68* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.22815499
69P300_19829295_ChIP-Seq_ESCs_Human1.22662614
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.21755535
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.20942143
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17200649
73MYC_22102868_ChIP-Seq_BL_Human1.16709899
74MYC_18940864_ChIP-ChIP_HL60_Human1.16688983
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16543891
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.15967654
77SRF_21415370_ChIP-Seq_HL-1_Mouse1.15928592
78* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15084770
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14492177
80GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.13119659
81ZFP57_27257070_Chip-Seq_ESCs_Mouse1.12061397
82MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11197099
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07755922
84GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07409336
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07370153
86EWS_26573619_Chip-Seq_HEK293_Human1.07040495
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06936377
88RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05754785
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03912590
90* TFEB_21752829_ChIP-Seq_HELA_Human1.01274184
91POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.01112785
92POU5F1_16153702_ChIP-ChIP_HESCs_Human0.99285841
93CTBP2_25329375_ChIP-Seq_LNCAP_Human0.98629512
94PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.96846524
95RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.96821686
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96032016
97SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.95434674
98FUS_26573619_Chip-Seq_HEK293_Human0.92880287
99NANOG_21062744_ChIP-ChIP_HESCs_Human0.91700060
100PCGF2_27294783_Chip-Seq_ESCs_Mouse0.91369095
101CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90934350
102* HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.89243879
103AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88361100
104RNF2_27304074_Chip-Seq_NSC_Mouse0.88234554
105GATA1_26923725_Chip-Seq_HPCs_Mouse0.88093233
106SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.85352101
107KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84213725
108CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.84110917
109NANOG_16153702_ChIP-ChIP_HESCs_Human0.83533805
110MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.83121560
111* SOX17_20123909_ChIP-Seq_XEN_Mouse0.81872348
112CBP_20019798_ChIP-Seq_JUKART_Human0.81532760
113IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81532760
114ELK1_22589737_ChIP-Seq_MCF10A_Human0.80639249
115BMI1_23680149_ChIP-Seq_NPCS_Mouse0.80567553
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.80286467
117SMAD3_21741376_ChIP-Seq_EPCs_Human0.80284004
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79853424
119SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.79608124
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.79143267
121FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.78244507
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77256976
123KLF4_18555785_ChIP-Seq_MESCs_Mouse0.77204440
124FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.76946468
125SOX9_26525672_Chip-Seq_HEART_Mouse0.76853246
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.76566833
127TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76566833
128* CHD1_26751641_Chip-Seq_LNCaP_Human0.75793132
129SPI1_23547873_ChIP-Seq_NB4_Human0.73079839
130IRF1_19129219_ChIP-ChIP_H3396_Human0.72435803
131PKCTHETA_26484144_Chip-Seq_BREAST_Human0.72132903
132CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.71692636
133DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.70627525
134NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.69011193
135* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.68481105
136FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.67632241

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.53221717
2MP0003693_abnormal_embryo_hatching4.13711954
3MP0010094_abnormal_chromosome_stability3.91839151
4MP0003111_abnormal_nucleus_morphology3.59494098
5MP0004957_abnormal_blastocyst_morpholog3.56572821
6MP0003077_abnormal_cell_cycle3.45216261
7MP0008007_abnormal_cellular_replicative3.19564927
8MP0008058_abnormal_DNA_repair3.12781949
9MP0008877_abnormal_DNA_methylation2.59109823
10MP0003123_paternal_imprinting2.50996806
11MP0008932_abnormal_embryonic_tissue2.24099758
12MP0002396_abnormal_hematopoietic_system2.23097810
13MP0003121_genomic_imprinting2.12140359
14MP0000566_synostosis2.10459311
15MP0001730_embryonic_growth_arrest2.05309950
16MP0010030_abnormal_orbit_morphology2.01728442
17MP0000350_abnormal_cell_proliferation1.93853618
18MP0010352_gastrointestinal_tract_polyps1.81893406
19MP0006292_abnormal_olfactory_placode1.73722025
20MP0003567_abnormal_fetal_cardiomyocyte1.70759734
21MP0001672_abnormal_embryogenesis/_devel1.69403800
22MP0005380_embryogenesis_phenotype1.69403800
23MP0009379_abnormal_foot_pigmentation1.68545937
24MP0010307_abnormal_tumor_latency1.65294994
25MP0003890_abnormal_embryonic-extraembry1.61979652
26MP0001697_abnormal_embryo_size1.61220392
27MP0003786_premature_aging1.57076986
28MP0003984_embryonic_growth_retardation1.56330979
29MP0004808_abnormal_hematopoietic_stem1.53381876
30MP0002088_abnormal_embryonic_growth/wei1.53031441
31MP0003937_abnormal_limbs/digits/tail_de1.52426922
32MP0002084_abnormal_developmental_patter1.52227405
33MP0002938_white_spotting1.51779006
34MP0001293_anophthalmia1.49854752
35MP0002085_abnormal_embryonic_tissue1.48553490
36MP0004197_abnormal_fetal_growth/weight/1.46783876
37MP0002163_abnormal_gland_morphology1.45251052
38MP0009053_abnormal_anal_canal1.39843496
39MP0003787_abnormal_imprinting1.34256973
40MP0008995_early_reproductive_senescence1.32454452
41MP0000490_abnormal_crypts_of1.32317084
42MP0002080_prenatal_lethality1.32073343
43MP0006072_abnormal_retinal_apoptosis1.27243878
44MP0002086_abnormal_extraembryonic_tissu1.24929476
45MP0005076_abnormal_cell_differentiation1.23896716
46MP0002234_abnormal_pharynx_morphology1.23013893
47MP0000631_abnormal_neuroendocrine_gland1.20193780
48MP0000313_abnormal_cell_death1.19221873
49MP0001188_hyperpigmentation1.18492453
50MP0008789_abnormal_olfactory_epithelium1.17843891
51MP0000569_abnormal_digit_pigmentation1.17183014
52MP0000428_abnormal_craniofacial_morphol1.15555420
53MP0000537_abnormal_urethra_morphology1.14892515
54MP0001529_abnormal_vocalization1.14410117
55MP0006054_spinal_hemorrhage1.12908575
56MP0002210_abnormal_sex_determination1.12789447
57MP0009672_abnormal_birth_weight1.10468798
58MP0005248_abnormal_Harderian_gland1.08089394
59MP0003315_abnormal_perineum_morphology1.05443535
60MP0000579_abnormal_nail_morphology1.05182848
61MP0003755_abnormal_palate_morphology1.04515035
62MP0009697_abnormal_copulation1.02039988
63MP0003136_yellow_coat_color1.00514219
64MP0003935_abnormal_craniofacial_develop1.00492848
65MP0009703_decreased_birth_body0.98887411
66MP0003385_abnormal_body_wall0.98755706
67MP0001145_abnormal_male_reproductive0.97756622
68MP0002019_abnormal_tumor_incidence0.97380515
69MP0002009_preneoplasia0.96851256
70MP0000432_abnormal_head_morphology0.96588366
71MP0003718_maternal_effect0.96444260
72MP0001286_abnormal_eye_development0.96146607
73MP0000703_abnormal_thymus_morphology0.95489923
74MP0005367_renal/urinary_system_phenotyp0.93835672
75MP0000516_abnormal_urinary_system0.93835672
76MP0001929_abnormal_gametogenesis0.93810549
77MP0003941_abnormal_skin_development0.92563620
78MP0003119_abnormal_digestive_system0.92130941
79MP0006276_abnormal_autonomic_nervous0.90589381
80MP0009250_abnormal_appendicular_skeleto0.88857953
81MP0000653_abnormal_sex_gland0.88781880
82MP0004133_heterotaxia0.88543988
83MP0003122_maternal_imprinting0.87174078
84MP0002160_abnormal_reproductive_system0.86995470
85MP0000049_abnormal_middle_ear0.86729939
86MP0005187_abnormal_penis_morphology0.86063276
87MP0003763_abnormal_thymus_physiology0.84978083
88MP0004147_increased_porphyrin_level0.82525221
89MP0003115_abnormal_respiratory_system0.81442109
90MP0001485_abnormal_pinna_reflex0.79487504
91MP0002111_abnormal_tail_morphology0.78944841
92MP0002092_abnormal_eye_morphology0.78835731
93MP0004215_abnormal_myocardial_fiber0.78745976
94MP0001119_abnormal_female_reproductive0.78279457
95MP0003698_abnormal_male_reproductive0.77449652
96MP0000647_abnormal_sebaceous_gland0.77305802
97MP0000778_abnormal_nervous_system0.76300702
98MP0002116_abnormal_craniofacial_bone0.76023311
99MP0005391_vision/eye_phenotype0.75191375
100MP0000383_abnormal_hair_follicle0.75016208
101MP0002102_abnormal_ear_morphology0.74611379
102MP0002233_abnormal_nose_morphology0.74491800
103MP0002114_abnormal_axial_skeleton0.74163535
104MP0005253_abnormal_eye_physiology0.72835048
105MP0002697_abnormal_eye_size0.71212671
106MP0003942_abnormal_urinary_system0.71072525
107MP0000372_irregular_coat_pigmentation0.70795893
108MP0006035_abnormal_mitochondrial_morpho0.70440922
109MP0003943_abnormal_hepatobiliary_system0.70107947
110MP0001299_abnormal_eye_distance/0.69347802
111MP0003938_abnormal_ear_development0.69226275
112MP0002177_abnormal_outer_ear0.68893361
113MP0005389_reproductive_system_phenotype0.68689719
114MP0001177_atelectasis0.67578256
115MP0004134_abnormal_chest_morphology0.67328109
116MP0002081_perinatal_lethality0.67193956
117MP0002932_abnormal_joint_morphology0.66956358
118MP0003861_abnormal_nervous_system0.66925960
119MP0002925_abnormal_cardiovascular_devel0.64854841
120MP0002398_abnormal_bone_marrow0.64638198
121MP0002109_abnormal_limb_morphology0.64564961
122MP0001545_abnormal_hematopoietic_system0.63769878
123MP0005397_hematopoietic_system_phenotyp0.63769878
124MP0005499_abnormal_olfactory_system0.63393440
125MP0005394_taste/olfaction_phenotype0.63393440
126MP0009333_abnormal_splenocyte_physiolog0.62958172
127MP0002751_abnormal_autonomic_nervous0.61256481
128MP0002095_abnormal_skin_pigmentation0.60983929

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.28100011
2Chromsome breakage (HP:0040012)3.90865403
3Volvulus (HP:0002580)3.76407966
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.42696759
5Colon cancer (HP:0003003)3.25541408
6Patellar aplasia (HP:0006443)3.18407684
7Diastasis recti (HP:0001540)3.07224192
8Abnormality of chromosome stability (HP:0003220)3.05484591
9Aplasia/Hypoplasia of the patella (HP:0006498)3.00015200
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.89197667
11Short 4th metacarpal (HP:0010044)2.89197667
12Meckel diverticulum (HP:0002245)2.86149973
13Ectopic kidney (HP:0000086)2.86060900
14Medulloblastoma (HP:0002885)2.84342001
15Breast hypoplasia (HP:0003187)2.82230828
16Abnormal lung lobation (HP:0002101)2.80829303
17Facial hemangioma (HP:0000329)2.78609347
18Abnormality of the labia minora (HP:0012880)2.75763229
19Abnormality of the preputium (HP:0100587)2.70799526
20Abnormality of the ileum (HP:0001549)2.67900237
21Nephroblastoma (Wilms tumor) (HP:0002667)2.65848646
22Abnormality of the fingertips (HP:0001211)2.61234063
23Embryonal renal neoplasm (HP:0011794)2.56219483
24Myelodysplasia (HP:0002863)2.55710052
25Aplasia/Hypoplasia of the sternum (HP:0006714)2.53065510
26Aplasia/Hypoplasia of the uvula (HP:0010293)2.52595059
27Increased nuchal translucency (HP:0010880)2.49494370
28Pancreatic cysts (HP:0001737)2.48378862
29Atresia of the external auditory canal (HP:0000413)2.46234312
30Proximal placement of thumb (HP:0009623)2.44837267
31Selective tooth agenesis (HP:0001592)2.44435621
32Duodenal stenosis (HP:0100867)2.44338727
33Small intestinal stenosis (HP:0012848)2.44338727
34Degeneration of anterior horn cells (HP:0002398)2.37889118
35Abnormality of the anterior horn cell (HP:0006802)2.37889118
36Deviation of the thumb (HP:0009603)2.37870464
37Long eyelashes (HP:0000527)2.37739714
38Aplastic anemia (HP:0001915)2.32918807
39Sloping forehead (HP:0000340)2.31320495
40Spinal cord lesions (HP:0100561)2.25780141
41Syringomyelia (HP:0003396)2.25780141
42Septo-optic dysplasia (HP:0100842)2.25399253
4311 pairs of ribs (HP:0000878)2.23550989
44Impulsivity (HP:0100710)2.21500716
45Abnormality of the metopic suture (HP:0005556)2.21118836
46Duplicated collecting system (HP:0000081)2.16885710
47Small hand (HP:0200055)2.11821897
48Horseshoe kidney (HP:0000085)2.11309539
49Abnormal number of incisors (HP:0011064)2.08995018
50Acute myeloid leukemia (HP:0004808)2.07316426
51Reticulocytopenia (HP:0001896)2.06862371
52Vertebral arch anomaly (HP:0008438)2.05934163
53Abnormality of the duodenum (HP:0002246)2.05851484
54Deep philtrum (HP:0002002)2.02634273
55Bone marrow hypocellularity (HP:0005528)1.99781411
56Intestinal atresia (HP:0011100)1.99194102
57Abnormality of cells of the erythroid lineage (HP:0012130)1.97863040
58Hemivertebrae (HP:0002937)1.97510899
59True hermaphroditism (HP:0010459)1.96590600
60Abnormal number of erythroid precursors (HP:0012131)1.95769763
61Microtia (HP:0008551)1.95397981
62Broad alveolar ridges (HP:0000187)1.94493396
63Bilateral microphthalmos (HP:0007633)1.93251421
64Facial cleft (HP:0002006)1.90547357
65Myelomeningocele (HP:0002475)1.87906384
66Supernumerary spleens (HP:0009799)1.87462725
67Protruding tongue (HP:0010808)1.87450823
68Capillary hemangiomas (HP:0005306)1.87357492
69Abnormality of the 4th metacarpal (HP:0010012)1.87166909
70Premature graying of hair (HP:0002216)1.86876561
71Hypoplastic labia majora (HP:0000059)1.85492096
72Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.84759295
73Neoplasm of the pancreas (HP:0002894)1.84637245
74Breast carcinoma (HP:0003002)1.83785596
75Abnormality of the septum pellucidum (HP:0007375)1.83747842
76Anomalous pulmonary venous return (HP:0010772)1.82182135
77Short thumb (HP:0009778)1.81675429
78Abnormality of the pons (HP:0007361)1.81538339
79Gonadotropin excess (HP:0000837)1.81235647
80Absent radius (HP:0003974)1.80484770
81Esophageal atresia (HP:0002032)1.79184529
82Abnormality of the carotid arteries (HP:0005344)1.78415574
83Rough bone trabeculation (HP:0100670)1.77892203
84Rhabdomyosarcoma (HP:0002859)1.76664269
85Hypoplasia of the pons (HP:0012110)1.76047013
86Prominent nose (HP:0000448)1.76027384
87Oral leukoplakia (HP:0002745)1.75422144
88Triphalangeal thumb (HP:0001199)1.75420568
89Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74759350
90Abnormality of alanine metabolism (HP:0010916)1.74759350
91Hyperalaninemia (HP:0003348)1.74759350
92Nephronophthisis (HP:0000090)1.74581471
93Gastrointestinal atresia (HP:0002589)1.73964840
94Long clavicles (HP:0000890)1.73294747
95Preaxial hand polydactyly (HP:0001177)1.72432288
96Oligodactyly (hands) (HP:0001180)1.71895109
97Abnormality of the labia majora (HP:0012881)1.71615242
98Astigmatism (HP:0000483)1.71614656
99Absent septum pellucidum (HP:0001331)1.70781419
100Congenital, generalized hypertrichosis (HP:0004540)1.69932742
101Abnormal pancreas size (HP:0012094)1.69821663
102Short middle phalanx of the 5th finger (HP:0004220)1.69749956
103Rib fusion (HP:0000902)1.69647435
104Neoplasm of the colon (HP:0100273)1.69600015
105Clubbing of toes (HP:0100760)1.69593780
106Partial agenesis of the corpus callosum (HP:0001338)1.69545579
107Aplasia/Hypoplasia of the tibia (HP:0005772)1.68266021
108Cellular immunodeficiency (HP:0005374)1.67755154
109Neoplasm of the oral cavity (HP:0100649)1.67391711
110Tracheoesophageal fistula (HP:0002575)1.67222213
111Optic nerve coloboma (HP:0000588)1.67110755
112Carpal bone hypoplasia (HP:0001498)1.67042350
113Dandy-Walker malformation (HP:0001305)1.66720076
114Microglossia (HP:0000171)1.66084575
115Abnormality of homocysteine metabolism (HP:0010919)1.65762504
116Homocystinuria (HP:0002156)1.65762504
117Glioma (HP:0009733)1.65545772
118Absent thumb (HP:0009777)1.65520773
119Cortical dysplasia (HP:0002539)1.65234645
120Prominent metopic ridge (HP:0005487)1.65111452
121Abnormality of abdominal situs (HP:0011620)1.65046507
122Abdominal situs inversus (HP:0003363)1.65046507
123Agnosia (HP:0010524)1.64572859
124Lip pit (HP:0100267)1.64508168
125Oligodactyly (HP:0012165)1.64280065
126Pendular nystagmus (HP:0012043)1.63963557
127Squamous cell carcinoma (HP:0002860)1.62426056
128Absent forearm bone (HP:0003953)1.61910086
129Aplasia involving forearm bones (HP:0009822)1.61910086
130Broad thumb (HP:0011304)1.61160692
131Molar tooth sign on MRI (HP:0002419)1.60655366
132Abnormality of midbrain morphology (HP:0002418)1.60655366
133Abnormality of the intervertebral disk (HP:0005108)1.60616673
134Cutis marmorata (HP:0000965)1.59848559
135Abnormality of the incisor (HP:0000676)1.59835046
136Aplasia/Hypoplasia of the tongue (HP:0010295)1.59567635
137Pancreatic fibrosis (HP:0100732)1.58538270
138Arteriovenous malformation (HP:0100026)1.58293943
139Anophthalmia (HP:0000528)1.58205894
140Abnormality of the renal collecting system (HP:0004742)1.57986365
141Sclerocornea (HP:0000647)1.56200566
142Duplication of thumb phalanx (HP:0009942)1.56187849
143Papillary thyroid carcinoma (HP:0002895)1.56170797
144Cafe-au-lait spot (HP:0000957)1.56159465
145Glossoptosis (HP:0000162)1.56090878
146Oligohydramnios (HP:0001562)1.56043143
147Bifid tongue (HP:0010297)1.55717006
148Hepatoblastoma (HP:0002884)1.54734266
149Gastrointestinal carcinoma (HP:0002672)1.54711784
150Malignant gastrointestinal tract tumors (HP:0006749)1.54711784
151Anencephaly (HP:0002323)1.54565585
152Hypoplasia of the capital femoral epiphysis (HP:0003090)1.54532102
153Ependymoma (HP:0002888)1.53696398

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.66342537
2BUB14.16171675
3WEE13.61004257
4MKNK13.32014106
5SRPK13.26419759
6MKNK22.96841587
7EIF2AK12.65752156
8BRSK22.60108074
9TNIK2.50109345
10PLK42.38885429
11TTK2.30258008
12CDK122.24051677
13PLK32.22299223
14NUAK12.15016048
15TSSK62.14418213
16NEK22.12032988
17BMPR1B1.93310074
18ATR1.91272162
19BRD41.88978223
20PLK11.87012665
21AURKB1.74551867
22BLK1.74171181
23TAF11.73683391
24WNK31.72603628
25LATS11.69255103
26ACVR1B1.64486740
27RPS6KA41.63288400
28EIF2AK31.57895461
29CHEK21.57659904
30PASK1.57087644
31VRK11.52723144
32CDK71.49401456
33DYRK31.48922099
34CHEK11.43733896
35PNCK1.43245636
36ZAK1.36664529
37STK31.35064968
38TRIM281.19905967
39ERBB31.19798780
40ATM1.19475248
41VRK21.17761926
42BRSK11.12900265
43CCNB11.09164627
44RPS6KB21.09136780
45CDK41.07994814
46STK41.07515274
47STK101.07083846
48AURKA1.06831185
49CDK61.03099862
50INSRR1.00711267
51CDK80.99076845
52WNK40.95731129
53PBK0.95014134
54CDK20.93909420
55NME10.93531772
56PDK20.93323990
57AKT30.90423894
58TGFBR10.90182391
59MELK0.87481126
60STK38L0.86875279
61STK160.86601114
62MAP3K40.86600432
63CDK10.84912667
64CAMK1G0.84325919
65CLK10.82689913
66YES10.82104531
67EIF2AK20.79255321
68NEK10.77870073
69MAP3K80.70925677
70CSNK2A20.68361394
71CSNK2A10.65746560
72STK390.65432930
73MAP4K20.63814439
74CAMK1D0.62585278
75PIM10.59930699
76GRK10.59899400
77RPS6KA50.59352428
78MARK30.58618204
79NME20.58255963
80CASK0.57817677
81CDK30.57015126
82PAK40.56546205
83FRK0.55731504
84CSNK1A1L0.53337064
85MAPK130.53289343
86PRKCI0.50955788
87TEC0.49139812
88NEK90.48971942
89CSNK1E0.48398480
90MAPK140.46918408
91PRKDC0.46582935
92ALK0.46134625
93MTOR0.46109652
94FGFR10.44376351
95CSNK1G30.43697009
96TLK10.42722952
97EPHA20.42015824
98ADRBK20.41230527
99CHUK0.39766032
100MAP3K100.38896637
101IRAK40.38611416
102PAK10.38203653
103PIM20.37819903
104EEF2K0.37731511
105BRAF0.37535382
106DYRK20.36147989
107CSNK1G10.35555184
108PAK30.35492630
109RPS6KB10.34475072
110TAOK30.34000629
111PLK20.33614022
112OXSR10.32366468
113GSK3B0.31023203
114JAK30.30837272
115BCR0.30136003
116CAMK40.30110470
117MST40.29620128
118AKT10.28998109
119NLK0.26168159
120ERBB40.26123649
121WNK10.25953567
122MAPK10.25260528
123CDK90.20910538
124CSNK1D0.20613349
125FLT30.20510371
126PAK20.20222393

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.00394609
2Mismatch repair_Homo sapiens_hsa034303.62932933
3Spliceosome_Homo sapiens_hsa030403.54057916
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.49532562
5RNA transport_Homo sapiens_hsa030133.28304378
6Cell cycle_Homo sapiens_hsa041103.24128798
7RNA polymerase_Homo sapiens_hsa030203.15865025
8Homologous recombination_Homo sapiens_hsa034402.98715485
9Base excision repair_Homo sapiens_hsa034102.81159345
10Non-homologous end-joining_Homo sapiens_hsa034502.80088171
11Nucleotide excision repair_Homo sapiens_hsa034202.66068745
12Proteasome_Homo sapiens_hsa030502.55543608
13Fanconi anemia pathway_Homo sapiens_hsa034602.54366115
14Basal transcription factors_Homo sapiens_hsa030222.42921888
15RNA degradation_Homo sapiens_hsa030182.37185171
16mRNA surveillance pathway_Homo sapiens_hsa030152.32619009
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.10888274
18One carbon pool by folate_Homo sapiens_hsa006702.03282825
19Ribosome_Homo sapiens_hsa030102.01862544
20Pyrimidine metabolism_Homo sapiens_hsa002401.95356941
21p53 signaling pathway_Homo sapiens_hsa041151.74580895
22Protein export_Homo sapiens_hsa030601.70038239
23Parkinsons disease_Homo sapiens_hsa050121.37011076
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36728425
25Epstein-Barr virus infection_Homo sapiens_hsa051691.34832438
26Oxidative phosphorylation_Homo sapiens_hsa001901.33788571
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.32195934
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.31117398
29Steroid biosynthesis_Homo sapiens_hsa001001.18017451
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.13955032
31Purine metabolism_Homo sapiens_hsa002301.13870454
32Propanoate metabolism_Homo sapiens_hsa006401.12611552
33Herpes simplex infection_Homo sapiens_hsa051681.12437180
34Oocyte meiosis_Homo sapiens_hsa041141.11541203
35MicroRNAs in cancer_Homo sapiens_hsa052061.10430798
36Pyruvate metabolism_Homo sapiens_hsa006201.09740573
37Viral carcinogenesis_Homo sapiens_hsa052031.02685260
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.99374647
39Antigen processing and presentation_Homo sapiens_hsa046120.94298105
40HTLV-I infection_Homo sapiens_hsa051660.93221886
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.91113961
42Transcriptional misregulation in cancer_Homo sapiens_hsa052020.91024804
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.86668701
44TGF-beta signaling pathway_Homo sapiens_hsa043500.84988426
45Basal cell carcinoma_Homo sapiens_hsa052170.82058007
46Small cell lung cancer_Homo sapiens_hsa052220.77495504
47Adherens junction_Homo sapiens_hsa045200.76905718
48Systemic lupus erythematosus_Homo sapiens_hsa053220.75817412
49Alzheimers disease_Homo sapiens_hsa050100.73571688
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70197977
51Hippo signaling pathway_Homo sapiens_hsa043900.69925960
52Taste transduction_Homo sapiens_hsa047420.69835837
53Thyroid cancer_Homo sapiens_hsa052160.69602542
54Prostate cancer_Homo sapiens_hsa052150.68880605
55Cardiac muscle contraction_Homo sapiens_hsa042600.68518115
56Olfactory transduction_Homo sapiens_hsa047400.66309499
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64614958
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64464546
59Hedgehog signaling pathway_Homo sapiens_hsa043400.62452311
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62423266
61Primary immunodeficiency_Homo sapiens_hsa053400.62003435
62Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61619036
63Colorectal cancer_Homo sapiens_hsa052100.61470461
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59169034
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.58596385
66Butanoate metabolism_Homo sapiens_hsa006500.56315230
67Nicotine addiction_Homo sapiens_hsa050330.56075472
68Viral myocarditis_Homo sapiens_hsa054160.54622982
69Legionellosis_Homo sapiens_hsa051340.54521638
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54157284
71Measles_Homo sapiens_hsa051620.52957128
72Hepatitis B_Homo sapiens_hsa051610.52580121
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51204413
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.50987261
75Chronic myeloid leukemia_Homo sapiens_hsa052200.50898171
76Selenocompound metabolism_Homo sapiens_hsa004500.49858493
77Lysine degradation_Homo sapiens_hsa003100.49523779
78Nitrogen metabolism_Homo sapiens_hsa009100.49032865
79Pathways in cancer_Homo sapiens_hsa052000.48449849
80Wnt signaling pathway_Homo sapiens_hsa043100.47777428
81Melanoma_Homo sapiens_hsa052180.47039538
82Shigellosis_Homo sapiens_hsa051310.45128764
83Vitamin digestion and absorption_Homo sapiens_hsa049770.44086891
84N-Glycan biosynthesis_Homo sapiens_hsa005100.43721914
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43217423
86Notch signaling pathway_Homo sapiens_hsa043300.42729291
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42419768
88FoxO signaling pathway_Homo sapiens_hsa040680.41316723
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41012377
90Apoptosis_Homo sapiens_hsa042100.37275980
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.36790591
92Hematopoietic cell lineage_Homo sapiens_hsa046400.36633503
93Metabolic pathways_Homo sapiens_hsa011000.35073630
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.34938464
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.34823679
96Endometrial cancer_Homo sapiens_hsa052130.33660959
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33601905
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32938471
99Pancreatic cancer_Homo sapiens_hsa052120.32868500
1002-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.32553203
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31876981
102PI3K-Akt signaling pathway_Homo sapiens_hsa041510.31529027
103Tight junction_Homo sapiens_hsa045300.30763201
104Asthma_Homo sapiens_hsa053100.30343334
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.30264361
106Influenza A_Homo sapiens_hsa051640.28756056
107Circadian rhythm_Homo sapiens_hsa047100.28020922
108Proteoglycans in cancer_Homo sapiens_hsa052050.26314840
109Alcoholism_Homo sapiens_hsa050340.25078401
110Non-small cell lung cancer_Homo sapiens_hsa052230.24959703
111Retinol metabolism_Homo sapiens_hsa008300.24813107
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24118911
113Arachidonic acid metabolism_Homo sapiens_hsa005900.23616379
114Huntingtons disease_Homo sapiens_hsa050160.22558890
115T cell receptor signaling pathway_Homo sapiens_hsa046600.22397098
116Autoimmune thyroid disease_Homo sapiens_hsa053200.22371960
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.21976778
118Bladder cancer_Homo sapiens_hsa052190.21910290
119Allograft rejection_Homo sapiens_hsa053300.20734015
120HIF-1 signaling pathway_Homo sapiens_hsa040660.20663421
121Cysteine and methionine metabolism_Homo sapiens_hsa002700.20534653
122Acute myeloid leukemia_Homo sapiens_hsa052210.20190911
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19707796
124Folate biosynthesis_Homo sapiens_hsa007900.19438087
125Renal cell carcinoma_Homo sapiens_hsa052110.19295421
126Maturity onset diabetes of the young_Homo sapiens_hsa049500.19281449
127Linoleic acid metabolism_Homo sapiens_hsa005910.19228461
128Peroxisome_Homo sapiens_hsa041460.19219078
129Jak-STAT signaling pathway_Homo sapiens_hsa046300.18500422
130Regulation of actin cytoskeleton_Homo sapiens_hsa048100.17680929
131Thyroid hormone signaling pathway_Homo sapiens_hsa049190.17418762
132Renin-angiotensin system_Homo sapiens_hsa046140.16725014
133Caffeine metabolism_Homo sapiens_hsa002320.16493045
134Vitamin B6 metabolism_Homo sapiens_hsa007500.16454545
135Fatty acid degradation_Homo sapiens_hsa000710.16190097
136Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.16158695
137Sulfur relay system_Homo sapiens_hsa041220.16112012
138Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.15792603
139Tryptophan metabolism_Homo sapiens_hsa003800.15287108
140Pentose phosphate pathway_Homo sapiens_hsa000300.14441728
141Focal adhesion_Homo sapiens_hsa045100.14349921
142Fatty acid metabolism_Homo sapiens_hsa012120.14041837
143Phototransduction_Homo sapiens_hsa047440.13827561
144alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12862741
145ECM-receptor interaction_Homo sapiens_hsa045120.12039066
146Steroid hormone biosynthesis_Homo sapiens_hsa001400.11310649
147beta-Alanine metabolism_Homo sapiens_hsa004100.10190465

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