CASC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)5.87316915
2mitotic chromosome condensation (GO:0007076)5.81319535
3mitotic sister chromatid segregation (GO:0000070)5.77921019
4* protein localization to kinetochore (GO:0034501)5.75514556
5sister chromatid segregation (GO:0000819)5.70281972
6nuclear pore complex assembly (GO:0051292)5.14734246
7* protein localization to chromosome, centromeric region (GO:0071459)5.07673682
8nuclear pore organization (GO:0006999)4.97234297
9kinetochore assembly (GO:0051382)4.89796261
10meiotic chromosome segregation (GO:0045132)4.87063879
11DNA unwinding involved in DNA replication (GO:0006268)4.72051539
12mitotic metaphase plate congression (GO:0007080)4.66824144
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.60755258
14regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.60372545
15* CENP-A containing nucleosome assembly (GO:0034080)4.57166142
16* chromatin remodeling at centromere (GO:0031055)4.53594743
17metaphase plate congression (GO:0051310)4.50690514
18DNA replication checkpoint (GO:0000076)4.46597739
19DNA replication-dependent nucleosome assembly (GO:0006335)4.40837445
20DNA replication-dependent nucleosome organization (GO:0034723)4.40837445
21mitotic sister chromatid cohesion (GO:0007064)4.37165097
22DNA double-strand break processing (GO:0000729)4.26742770
23* DNA replication-independent nucleosome assembly (GO:0006336)4.22739332
24* DNA replication-independent nucleosome organization (GO:0034724)4.22739332
25* attachment of spindle microtubules to kinetochore (GO:0008608)4.20381069
26DNA replication initiation (GO:0006270)4.19080590
27establishment of chromosome localization (GO:0051303)4.18487629
28mitotic recombination (GO:0006312)4.16876389
29regulation of spindle organization (GO:0090224)4.13001635
30telomere maintenance via semi-conservative replication (GO:0032201)4.05311541
31pore complex assembly (GO:0046931)4.04513315
32DNA strand elongation involved in DNA replication (GO:0006271)4.03655799
33mitotic nuclear envelope disassembly (GO:0007077)4.00394153
34chromosome segregation (GO:0007059)3.99895844
35regulation of nuclear cell cycle DNA replication (GO:0033262)3.96766489
36DNA topological change (GO:0006265)3.96492037
37chromosome condensation (GO:0030261)3.91559563
38telomere maintenance via recombination (GO:0000722)3.90763644
39DNA strand elongation (GO:0022616)3.84982314
40* histone exchange (GO:0043486)3.79825734
41* chromatin assembly or disassembly (GO:0006333)3.79224953
42DNA geometric change (GO:0032392)3.78670740
43DNA duplex unwinding (GO:0032508)3.77190059
44regulation of mitotic spindle organization (GO:0060236)3.74379958
45regulation of DNA endoreduplication (GO:0032875)3.74193445
46regulation of chromosome segregation (GO:0051983)3.74006999
47nuclear envelope disassembly (GO:0051081)3.70151698
48membrane disassembly (GO:0030397)3.70151698
49* spindle checkpoint (GO:0031577)3.68563791
50establishment of integrated proviral latency (GO:0075713)3.67860424
51regulation of histone H3-K9 methylation (GO:0051570)3.65102861
52purine nucleobase biosynthetic process (GO:0009113)3.64245933
53microtubule depolymerization (GO:0007019)3.61280436
54regulation of mitotic metaphase/anaphase transition (GO:0030071)3.60734169
55ribosome assembly (GO:0042255)3.59866372
56double-strand break repair via nonhomologous end joining (GO:0006303)3.59267952
57non-recombinational repair (GO:0000726)3.59267952
58positive regulation of mitotic sister chromatid separation (GO:1901970)3.58360362
59positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.58360362
60positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.58360362
61* protein localization to chromosome (GO:0034502)3.56490687
62negative regulation of chromosome segregation (GO:0051985)3.55910748
63positive regulation of chromosome segregation (GO:0051984)3.55068274
64DNA packaging (GO:0006323)3.54774006
65DNA conformation change (GO:0071103)3.54058679
66negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.53308780
67negative regulation of sister chromatid segregation (GO:0033046)3.53308780
68negative regulation of mitotic sister chromatid separation (GO:2000816)3.53308780
69negative regulation of mitotic sister chromatid segregation (GO:0033048)3.53308780
70regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.52503340
71negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.52013640
72regulation of mitotic sister chromatid separation (GO:0010965)3.46776316
73regulation of mitotic sister chromatid segregation (GO:0033047)3.46776316
74regulation of sister chromatid segregation (GO:0033045)3.46776316
75resolution of meiotic recombination intermediates (GO:0000712)3.44747132
76* spindle assembly checkpoint (GO:0071173)3.44246781
77mitotic spindle assembly checkpoint (GO:0007094)3.44246781
78negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.42875513
79DNA catabolic process, exonucleolytic (GO:0000738)3.42246837
80regulation of telomere maintenance via telomerase (GO:0032210)3.42006338
81regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.41973390
82mitotic spindle checkpoint (GO:0071174)3.41020003
83negative regulation of cell cycle G2/M phase transition (GO:1902750)3.40781786
84chromatin assembly (GO:0031497)3.40460171
85deoxyribonucleotide biosynthetic process (GO:0009263)3.39995432
86negative regulation of mitosis (GO:0045839)3.39079072
87postreplication repair (GO:0006301)3.38947830
88DNA strand renaturation (GO:0000733)3.36441607
89regulation of centrosome cycle (GO:0046605)3.34165653
90* mitotic cell cycle (GO:0000278)3.33533218
91protein K6-linked ubiquitination (GO:0085020)3.33293463
92IMP biosynthetic process (GO:0006188)3.32671400
93nucleobase biosynthetic process (GO:0046112)3.30455855
94telomere maintenance via telomere lengthening (GO:0010833)3.30298270
95regulation of sister chromatid cohesion (GO:0007063)3.30117588
96regulation of centriole replication (GO:0046599)3.28166897
97positive regulation of DNA-dependent DNA replication (GO:2000105)3.26432998
98maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.24791605
99* ATP-dependent chromatin remodeling (GO:0043044)3.24171072
100nucleotide-excision repair, DNA gap filling (GO:0006297)3.22644403
101mitotic spindle organization (GO:0007052)3.22280144
102negative regulation of DNA-dependent DNA replication (GO:2000104)3.21280116
103mitotic G2 DNA damage checkpoint (GO:0007095)3.21136124
104sister chromatid cohesion (GO:0007062)3.20704965
105DNA ligation (GO:0006266)3.16343081
106mitotic G2/M transition checkpoint (GO:0044818)3.15788388
107regulation of double-strand break repair via homologous recombination (GO:0010569)3.15516368
108translesion synthesis (GO:0019985)3.07663375
109replication fork processing (GO:0031297)3.05773165
110regulation of DNA-dependent DNA replication (GO:0090329)3.05671338
111regulation of double-strand break repair (GO:2000779)3.05451318
112telomere maintenance (GO:0000723)3.03011529
113DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.02790731
114dosage compensation (GO:0007549)3.00502182
115heterochromatin organization (GO:0070828)3.00150548
116telomere organization (GO:0032200)2.98918004
117DNA synthesis involved in DNA repair (GO:0000731)2.95286230
118chromosome organization (GO:0051276)2.95116447

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human7.22803765
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human5.32872555
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.45239088
4* MYC_18555785_ChIP-Seq_MESCs_Mouse3.05347412
5AR_21909140_ChIP-Seq_LNCAP_Human2.59299958
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.46070127
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.44339215
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.43155291
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.40255887
10* E2F1_21310950_ChIP-Seq_MCF-7_Human2.39669949
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.35658547
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.34098682
13* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.28923321
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.28832521
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.21592263
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.18810111
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.06425758
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.02358393
19E2F7_22180533_ChIP-Seq_HELA_Human11.3322709
20* EST1_17652178_ChIP-ChIP_JURKAT_Human1.97111797
21NELFA_20434984_ChIP-Seq_ESCs_Mouse1.96157324
22MYC_18358816_ChIP-ChIP_MESCs_Mouse1.90256142
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.89170565
24CREB1_15753290_ChIP-ChIP_HEK293T_Human1.80682287
25* VDR_23849224_ChIP-Seq_CD4+_Human1.72199568
26FOXP3_21729870_ChIP-Seq_TREG_Human1.70570254
27ELK1_19687146_ChIP-ChIP_HELA_Human1.67446188
28XRN2_22483619_ChIP-Seq_HELA_Human1.63197004
29MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57607920
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.56567912
31GABP_17652178_ChIP-ChIP_JURKAT_Human1.55364624
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53688618
33NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53515003
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.52212350
35* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51139316
36SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.50397423
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.48745679
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.45578628
39* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44650848
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44488146
41* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.43991736
42MYC_22102868_ChIP-Seq_BL_Human1.43375813
43EWS_26573619_Chip-Seq_HEK293_Human1.41391747
44* CIITA_25753668_ChIP-Seq_RAJI_Human1.40637004
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.38680907
46TTF2_22483619_ChIP-Seq_HELA_Human1.38646298
47JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.38416339
48* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.33564855
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30824519
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.29644467
51SRF_21415370_ChIP-Seq_HL-1_Mouse1.28479385
52KDM5A_27292631_Chip-Seq_BREAST_Human1.28255950
53* DCP1A_22483619_ChIP-Seq_HELA_Human1.27951212
54KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27894289
55KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27894289
56KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27894289
57* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24964427
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23580772
59* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.21960120
60* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.17636141
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16192418
62HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.15539681
63* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.14612699
64GABP_19822575_ChIP-Seq_HepG2_Human1.14368228
65FUS_26573619_Chip-Seq_HEK293_Human1.13425920
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13348340
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.12689465
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11648161
69PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08415188
70RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07874507
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07802887
72ZFX_18555785_ChIP-Seq_MESCs_Mouse1.06574491
73IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.01093365
74BP1_19119308_ChIP-ChIP_Hs578T_Human0.96562876
75STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96325245
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95426273
77SOX17_20123909_ChIP-Seq_XEN_Mouse0.94828861
78SPI1_23547873_ChIP-Seq_NB4_Human0.93019646
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.92678664
80SCL_19346495_ChIP-Seq_HPC-7_Human0.90425503
81TFEB_21752829_ChIP-Seq_HELA_Human0.90196706
82POU3F2_20337985_ChIP-ChIP_501MEL_Human0.89302234
83POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88491596
84* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88454527
85KLF4_18555785_ChIP-Seq_MESCs_Mouse0.87830422
86HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.87792223
87GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86806464
88MYC_18940864_ChIP-ChIP_HL60_Human0.86519103
89SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.85176133
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85030162
91VDR_21846776_ChIP-Seq_THP-1_Human0.84433216
92POU5F1_16153702_ChIP-ChIP_HESCs_Human0.84406569
93NANOG_21062744_ChIP-ChIP_HESCs_Human0.84268750
94RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83759371
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.83561260
96PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.83431625
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.82969100
98SOX2_16153702_ChIP-ChIP_HESCs_Human0.82758527
99FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.82151246
100CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81582936
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.81251259
102NOTCH1_21737748_ChIP-Seq_TLL_Human0.81129963
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80315380
104* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.79954431
105MYB_26560356_Chip-Seq_TH1_Human0.78482158
106* YY1_21170310_ChIP-Seq_MESCs_Mouse0.78334510
107NANOG_16153702_ChIP-ChIP_HESCs_Human0.77945225
108CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.76061744
109TCF3_18692474_ChIP-Seq_MESCs_Mouse0.75195726
110VDR_22108803_ChIP-Seq_LS180_Human0.74578067
111E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.74558913
112IGF1R_20145208_ChIP-Seq_DFB_Human0.74553078
113CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.73579407
114MYB_26560356_Chip-Seq_TH2_Human0.73128669
115DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.72462492
116BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.72078336
117TAF15_26573619_Chip-Seq_HEK293_Human0.69172026
118BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.68776438
119TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.64788643
120RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.62774963
121* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.62681269
122ZNF274_21170338_ChIP-Seq_K562_Hela0.61132774
123IRF1_19129219_ChIP-ChIP_H3396_Human0.60780606
124CHD1_26751641_Chip-Seq_LNCaP_Human0.58957833

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.88241869
2MP0008057_abnormal_DNA_replication4.79656554
3MP0003693_abnormal_embryo_hatching4.60488897
4MP0003111_abnormal_nucleus_morphology4.48311718
5MP0003077_abnormal_cell_cycle4.01268142
6MP0004957_abnormal_blastocyst_morpholog3.82875520
7MP0009697_abnormal_copulation3.13735920
8MP0008058_abnormal_DNA_repair2.96903073
9MP0008007_abnormal_cellular_replicative2.71078312
10MP0002396_abnormal_hematopoietic_system2.69891987
11MP0008932_abnormal_embryonic_tissue2.31354280
12MP0010307_abnormal_tumor_latency2.30206055
13MP0000350_abnormal_cell_proliferation2.20436826
14MP0010352_gastrointestinal_tract_polyps1.99669533
15MP0003121_genomic_imprinting1.96751158
16MP0008877_abnormal_DNA_methylation1.94441899
17MP0003123_paternal_imprinting1.93796030
18MP0003890_abnormal_embryonic-extraembry1.90260444
19MP0001730_embryonic_growth_arrest1.88003958
20MP0001672_abnormal_embryogenesis/_devel1.80340169
21MP0005380_embryogenesis_phenotype1.80340169
22MP0000490_abnormal_crypts_of1.77773968
23MP0003786_premature_aging1.75815647
24MP0000569_abnormal_digit_pigmentation1.73908648
25MP0004808_abnormal_hematopoietic_stem1.69705577
26MP0003984_embryonic_growth_retardation1.60587707
27MP0006292_abnormal_olfactory_placode1.57485804
28MP0002088_abnormal_embryonic_growth/wei1.57415619
29MP0001697_abnormal_embryo_size1.53905930
30MP0002085_abnormal_embryonic_tissue1.47474984
31MP0002086_abnormal_extraembryonic_tissu1.47208816
32MP0000313_abnormal_cell_death1.46146240
33MP0005076_abnormal_cell_differentiation1.43503116
34MP0003787_abnormal_imprinting1.38222767
35MP0002084_abnormal_developmental_patter1.37537342
36MP0006035_abnormal_mitochondrial_morpho1.37448575
37MP0004197_abnormal_fetal_growth/weight/1.37040123
38MP0002019_abnormal_tumor_incidence1.36309338
39MP0002080_prenatal_lethality1.35698253
40MP0004264_abnormal_extraembryonic_tissu1.35405258
41MP0002160_abnormal_reproductive_system1.31036727
42MP0008775_abnormal_heart_ventricle1.30889087
43MP0001346_abnormal_lacrimal_gland1.30540050
44MP0006072_abnormal_retinal_apoptosis1.27811990
45MP0001293_anophthalmia1.22573036
46MP0002234_abnormal_pharynx_morphology1.22007373
47MP0000703_abnormal_thymus_morphology1.21925660
48MP0002398_abnormal_bone_marrow1.18560004
49MP0005397_hematopoietic_system_phenotyp1.15761764
50MP0001545_abnormal_hematopoietic_system1.15761764
51MP0005408_hypopigmentation1.15466157
52MP0006036_abnormal_mitochondrial_physio1.12017806
53MP0002210_abnormal_sex_determination1.11654096
54MP0010030_abnormal_orbit_morphology1.11082120
55MP0003806_abnormal_nucleotide_metabolis1.10674891
56MP0003567_abnormal_fetal_cardiomyocyte1.10350625
57MP0005075_abnormal_melanosome_morpholog1.07850871
58MP0002722_abnormal_immune_system1.07470075
59MP0000358_abnormal_cell_content/1.06501522
60MP0003315_abnormal_perineum_morphology1.04660814
61MP0002102_abnormal_ear_morphology1.02400170
62MP0000689_abnormal_spleen_morphology1.01379647
63MP0004147_increased_porphyrin_level1.01295763
64MP0001145_abnormal_male_reproductive1.00383288
65MP0003937_abnormal_limbs/digits/tail_de0.99407856
66MP0003763_abnormal_thymus_physiology0.97293990
67MP0002095_abnormal_skin_pigmentation0.94785751
68MP0001929_abnormal_gametogenesis0.93991771
69MP0000383_abnormal_hair_follicle0.92319161
70MP0003705_abnormal_hypodermis_morpholog0.90943190
71MP0001835_abnormal_antigen_presentation0.89732767
72MP0005174_abnormal_tail_pigmentation0.87450939
73MP0009703_decreased_birth_body0.86682790
74MP0002429_abnormal_blood_cell0.85170050
75MP0006054_spinal_hemorrhage0.84870137
76MP0003698_abnormal_male_reproductive0.84834912
77MP0002092_abnormal_eye_morphology0.82428214
78MP0000653_abnormal_sex_gland0.81914850
79MP0003941_abnormal_skin_development0.81846515
80MP0000432_abnormal_head_morphology0.80836955
81MP0002269_muscular_atrophy0.80774185
82MP0001243_abnormal_dermal_layer0.79811920
83MP0005389_reproductive_system_phenotype0.79571253
84MP0001764_abnormal_homeostasis0.79561875
85MP0000858_altered_metastatic_potential0.79227128
86MP0001119_abnormal_female_reproductive0.78637587
87MP0009278_abnormal_bone_marrow0.78102618
88MP0002877_abnormal_melanocyte_morpholog0.77412616
89MP0001286_abnormal_eye_development0.76775755
90MP0003115_abnormal_respiratory_system0.76428982
91MP0009333_abnormal_splenocyte_physiolog0.76408566
92MP0000372_irregular_coat_pigmentation0.76117919
93MP0000716_abnormal_immune_system0.76114292
94MP0002009_preneoplasia0.75893457
95MP0001800_abnormal_humoral_immune0.75094636
96MP0005621_abnormal_cell_physiology0.74954422
97MP0005384_cellular_phenotype0.74619430
98MP0003935_abnormal_craniofacial_develop0.73107642
99MP0005395_other_phenotype0.72639559
100MP0002075_abnormal_coat/hair_pigmentati0.72347144
101MP0001661_extended_life_span0.71408372
102MP0003699_abnormal_female_reproductive0.71190415
103MP0002006_tumorigenesis0.70345429
104MP0000015_abnormal_ear_pigmentation0.69615660
105MP0009672_abnormal_birth_weight0.69424983
106MP0002161_abnormal_fertility/fecundity0.69144402
107MP0003119_abnormal_digestive_system0.68901842
108MP0003938_abnormal_ear_development0.68674192
109MP0008789_abnormal_olfactory_epithelium0.67920201
110MP0002111_abnormal_tail_morphology0.67837024
111MP0003943_abnormal_hepatobiliary_system0.67239383
112MP0003718_maternal_effect0.66545028
113MP0004233_abnormal_muscle_weight0.66379392
114MP0002970_abnormal_white_adipose0.66182971
115MP0000428_abnormal_craniofacial_morphol0.66097815
116MP0002938_white_spotting0.65689926
117MP0002166_altered_tumor_susceptibility0.64861600
118MP0003861_abnormal_nervous_system0.64678826
119MP0002925_abnormal_cardiovascular_devel0.63685828
120MP0003448_altered_tumor_morphology0.63623367
121MP0001529_abnormal_vocalization0.63313224
122MP0002420_abnormal_adaptive_immunity0.63204949
123MP0005391_vision/eye_phenotype0.62886070
124MP0001853_heart_inflammation0.62404539
125MP0001819_abnormal_immune_cell0.62201744
126MP0002452_abnormal_antigen_presenting0.62158874
127MP0003186_abnormal_redox_activity0.61163334
128MP0002697_abnormal_eye_size0.60674394
129MP0002233_abnormal_nose_morphology0.60443244
130MP0003221_abnormal_cardiomyocyte_apopto0.60293639
131MP0001915_intracranial_hemorrhage0.59827338
132MP0001186_pigmentation_phenotype0.59418424
133MP0005253_abnormal_eye_physiology0.58680669
134MP0002932_abnormal_joint_morphology0.57550011
135MP0002114_abnormal_axial_skeleton0.57337910
136MP0005023_abnormal_wound_healing0.57285460
137MP0003755_abnormal_palate_morphology0.57180877
138MP0003385_abnormal_body_wall0.56897192
139MP0009250_abnormal_appendicular_skeleto0.53697335
140MP0001919_abnormal_reproductive_system0.53493144
141MP0002163_abnormal_gland_morphology0.53220395

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)6.19904776
2Chromosomal breakage induced by crosslinking agents (HP:0003221)6.13085292
3Abnormality of chromosome stability (HP:0003220)4.24006542
4Meckel diverticulum (HP:0002245)3.89713906
5Volvulus (HP:0002580)3.83778850
6Aplasia/Hypoplasia of the uvula (HP:0010293)3.79893950
7Abnormality of the preputium (HP:0100587)3.73594963
8Abnormality of the ileum (HP:0001549)3.68754312
9Nephroblastoma (Wilms tumor) (HP:0002667)3.44980689
10Small intestinal stenosis (HP:0012848)3.44157088
11Duodenal stenosis (HP:0100867)3.44157088
12Reticulocytopenia (HP:0001896)3.36823316
13Myelodysplasia (HP:0002863)3.28836569
14Hypochromic microcytic anemia (HP:0004840)3.26702201
15Embryonal renal neoplasm (HP:0011794)3.19392523
16Abnormal lung lobation (HP:0002101)3.15411884
17Ectopic kidney (HP:0000086)3.15122264
18Birth length less than 3rd percentile (HP:0003561)3.06455437
19Ependymoma (HP:0002888)3.01651243
20Medulloblastoma (HP:0002885)3.01079258
21Increased nuchal translucency (HP:0010880)2.94728282
22Duplicated collecting system (HP:0000081)2.92708093
23Cortical dysplasia (HP:0002539)2.89261799
24Rhabdomyosarcoma (HP:0002859)2.88620582
25Sloping forehead (HP:0000340)2.86282909
26Abnormality of the duodenum (HP:0002246)2.79679566
27Clubbing of toes (HP:0100760)2.76846478
28Abnormality of the renal collecting system (HP:0004742)2.73209652
29Abnormality of the carotid arteries (HP:0005344)2.65556412
30Selective tooth agenesis (HP:0001592)2.63644784
31Posterior subcapsular cataract (HP:0007787)2.63203209
32Patellar aplasia (HP:0006443)2.57317342
33Bone marrow hypocellularity (HP:0005528)2.54761140
34Colon cancer (HP:0003003)2.50729149
35Cafe-au-lait spot (HP:0000957)2.37805191
36Absent radius (HP:0003974)2.37532272
3711 pairs of ribs (HP:0000878)2.35158810
38Prominent nose (HP:0000448)2.34084598
39Aplasia/Hypoplasia of the patella (HP:0006498)2.33970975
40Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.33623750
41Abnormality of alanine metabolism (HP:0010916)2.33623750
42Hyperalaninemia (HP:0003348)2.33623750
43Abnormality of chromosome segregation (HP:0002916)2.33222156
44Neoplasm of striated muscle (HP:0009728)2.30122833
45Short 4th metacarpal (HP:0010044)2.29963332
46Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.29963332
47Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26536446
48Abnormality of the astrocytes (HP:0100707)2.26224369
49Astrocytoma (HP:0009592)2.26224369
50Aplasia/Hypoplasia of the sternum (HP:0006714)2.22083813
51Agnosia (HP:0010524)2.19987545
52Aplastic anemia (HP:0001915)2.18975355
53Absent forearm bone (HP:0003953)2.18569540
54Aplasia involving forearm bones (HP:0009822)2.18569540
55Abnormality of the fingertips (HP:0001211)2.17768436
56Abnormality of the labia minora (HP:0012880)2.17063257
57Supernumerary spleens (HP:0009799)2.15217671
58Glioma (HP:0009733)2.14566107
59Absent thumb (HP:0009777)2.13982490
60* Impulsivity (HP:0100710)2.13323435
61Abnormality of DNA repair (HP:0003254)2.11540654
62Tracheoesophageal fistula (HP:0002575)2.11108125
63Triphalangeal thumb (HP:0001199)2.08938658
64Ovarian neoplasm (HP:0100615)2.06506018
65Atresia of the external auditory canal (HP:0000413)2.06374299
66Microvesicular hepatic steatosis (HP:0001414)2.03036035
67Increased serum pyruvate (HP:0003542)2.01031329
68Bilateral microphthalmos (HP:0007633)1.99661621
69Proximal placement of thumb (HP:0009623)1.98118395
70Short thumb (HP:0009778)1.97079612
71Abnormal number of incisors (HP:0011064)1.96877341
72Abnormality of the heme biosynthetic pathway (HP:0010472)1.96719992
73Neoplasm of the oral cavity (HP:0100649)1.95963092
74Abnormal umbilical cord blood vessels (HP:0011403)1.95863741
75Single umbilical artery (HP:0001195)1.95863741
76Abnormality of the fetal cardiovascular system (HP:0010948)1.95863741
77Deep philtrum (HP:0002002)1.95611498
78Microglossia (HP:0000171)1.94665499
79Oligohydramnios (HP:0001562)1.94628689
80Deviation of the thumb (HP:0009603)1.94136680
81Facial hemangioma (HP:0000329)1.91695164
82Breast hypoplasia (HP:0003187)1.91384483
83Abnormality of methionine metabolism (HP:0010901)1.89223866
84Absent frontal sinuses (HP:0002688)1.88801617
85Rib fusion (HP:0000902)1.88251584
86Hypochromic anemia (HP:0001931)1.87769003
87Megaloblastic anemia (HP:0001889)1.87680785
88High pitched voice (HP:0001620)1.87007684
89Horseshoe kidney (HP:0000085)1.85892609
90Abnormal number of erythroid precursors (HP:0012131)1.84593103
91Arteriovenous malformation (HP:0100026)1.84555963
92Missing ribs (HP:0000921)1.83057301
93Abnormality of glycolysis (HP:0004366)1.81796754
94Progressive external ophthalmoplegia (HP:0000590)1.80002856
95Embryonal neoplasm (HP:0002898)1.79381117
96Pancreatic islet-cell hyperplasia (HP:0004510)1.79114563
97Pallor (HP:0000980)1.79109146
98Short middle phalanx of the 5th finger (HP:0004220)1.77324231
99Astigmatism (HP:0000483)1.77067432
100Lymphoma (HP:0002665)1.76133142
101Leiomyosarcoma (HP:0100243)1.75620485
102Uterine leiomyosarcoma (HP:0002891)1.75620485
103Short tibia (HP:0005736)1.75057770
104Oligodactyly (hands) (HP:0001180)1.74105256
105Abnormality of cells of the erythroid lineage (HP:0012130)1.73240971
106Long eyelashes (HP:0000527)1.72545368
107Broad palm (HP:0001169)1.72163591
108Aplasia/Hypoplasia of the tibia (HP:0005772)1.71929211
109Leukopenia (HP:0001882)1.71702362
110Cleft eyelid (HP:0000625)1.71073820
111Oral leukoplakia (HP:0002745)1.70886363
112Neoplasm of the colon (HP:0100273)1.70837670
113Abnormality of the umbilical cord (HP:0010881)1.70767236
114Abnormality of cochlea (HP:0000375)1.70563826
115Acute myeloid leukemia (HP:0004808)1.70529445
116Combined immunodeficiency (HP:0005387)1.69790029
117Heterotopia (HP:0002282)1.68247815
118Abnormality of the anterior horn cell (HP:0006802)1.67922526
119Degeneration of anterior horn cells (HP:0002398)1.67922526
120Transitional cell carcinoma of the bladder (HP:0006740)1.67738785
121Basal cell carcinoma (HP:0002671)1.65885460
122Abnormality of homocysteine metabolism (HP:0010919)1.64924425
123Homocystinuria (HP:0002156)1.64924425
124Preauricular skin tag (HP:0000384)1.64226193
125IgM deficiency (HP:0002850)1.64139844
126Choanal atresia (HP:0000453)1.64088545
127Truncal obesity (HP:0001956)1.62934816
128Intestinal polyposis (HP:0200008)1.62679932
129Overlapping toe (HP:0001845)1.62650459
130Sandal gap (HP:0001852)1.62296657
131Aplasia/Hypoplasia of the earlobes (HP:0009906)1.61992189
132Oligodactyly (HP:0012165)1.61806704
133Premature graying of hair (HP:0002216)1.60315858
134Amaurosis fugax (HP:0100576)1.59309594
135Gout (HP:0001997)1.58865867
136Intestinal polyp (HP:0005266)1.57548463
137Bladder neoplasm (HP:0009725)1.57197588
138Bladder carcinoma (HP:0002862)1.57197588
139Squamous cell carcinoma (HP:0002860)1.56781078
140Dandy-Walker malformation (HP:0001305)1.56553505
141External ear malformation (HP:0008572)1.54921539
142Progressive muscle weakness (HP:0003323)1.54706308
143Long clavicles (HP:0000890)1.54426657

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.79798419
2CDK124.23563712
3WEE13.60495315
4NEK23.55625153
5BUB13.53424104
6TTK3.27016096
7BRSK23.04342907
8SRPK12.55435032
9PLK12.34180446
10TLK12.24022850
11NEK12.11788044
12ZAK2.06645886
13* AURKB2.06039106
14PLK42.05015602
15STK42.04128698
16CHEK22.02996135
17EIF2AK11.98216409
18ATR1.94232901
19STK101.80876903
20BRSK11.77498725
21ACVR1B1.73458217
22CDK71.73066933
23VRK11.68800075
24PLK31.64599462
25MKNK11.62800450
26TRIM281.59123094
27CCNB11.56772070
28CDK41.52603479
29CHEK11.52495140
30PNCK1.41713134
31MKNK21.37380929
32DYRK31.36784917
33BRD41.35965412
34ATM1.26242541
35MAP3K81.19719712
36EIF2AK21.19397161
37CDK61.18223075
38RPS6KB21.14618507
39MELK1.11232412
40CSF1R1.10438106
41RPS6KA41.09731880
42STK31.07660490
43AURKA1.02464137
44PIM10.98699651
45CLK10.97751880
46CDK20.97407576
47PASK0.91953833
48BMPR1B0.90174921
49SCYL20.89799630
50EIF2AK30.89768024
51GRK60.88761110
52CDK10.86925343
53EEF2K0.85126576
54PDK20.83761328
55ERBB30.82237937
56PLK20.82041732
57MAP3K100.80510082
58BRAF0.75295667
59MST40.74749526
60BCR0.73484328
61YES10.71284456
62LATS10.70715320
63VRK20.69081949
64RPS6KA50.68197008
65MAP4K10.64087684
66FLT30.63610808
67MARK30.61738100
68PAK40.61693871
69IRAK40.58574538
70STK160.57548764
71CDK30.57395675
72PBK0.56706862
73NUAK10.56677816
74TSSK60.56662059
75TESK20.55523641
76NME20.53737251
77CDK90.53636751
78MAP4K20.53130645
79EPHA20.52788092
80WNK30.52385901
81TAF10.50087085
82CDK80.49790288
83AKT20.47655342
84CDK180.46905652
85MAP3K40.45866448
86TGFBR10.45615753
87CDK150.44478809
88CHUK0.43519554
89MATK0.43401025
90TEC0.43184500
91CSNK2A10.43104323
92MAPK140.42960171
93NME10.42746094
94MST1R0.42474238
95MET0.41243033
96PRKDC0.41061844
97CDK11A0.40780692
98MAP2K70.40568625
99MTOR0.39028544
100CDK140.38784928
101CSNK2A20.36883807
102TRPM70.34856425
103AKT10.34227569
104KIT0.34063151
105ALK0.31319601
106CSNK1E0.30147919
107RPS6KB10.30088015
108CSNK1D0.30078004
109GRK10.28214192
110PAK10.28019034
111BTK0.27496736
112NEK90.27080008
113PRKCI0.27072339
114GSK3B0.26161856
115CSNK1G10.25756987
116ERBB40.25634862
117TNIK0.25428786
118TGFBR20.25149766
119STK390.24990921
120MAPK10.24952466
121ADRBK20.24596622
122STK38L0.22976605
123JAK30.21679805
124LYN0.20562694
125IRAK20.20467393
126FGFR10.20402701
127CAMK1D0.19223477
128FGFR30.19088397
129MAPKAPK20.18977538
130CAMKK20.18104917
131IKBKB0.17549724
132MAPK130.17047918
133HIPK20.17005566
134ERBB20.16701575
135CSNK1A1L0.16407293
136CSNK1G30.16284694
137IRAK10.12856750

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.76788613
2Mismatch repair_Homo sapiens_hsa034304.18034084
3Homologous recombination_Homo sapiens_hsa034403.42208091
4Cell cycle_Homo sapiens_hsa041103.38710169
5Fanconi anemia pathway_Homo sapiens_hsa034603.33735153
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.22016716
7Base excision repair_Homo sapiens_hsa034103.03811209
8Spliceosome_Homo sapiens_hsa030402.81218115
9RNA transport_Homo sapiens_hsa030132.78277988
10Non-homologous end-joining_Homo sapiens_hsa034502.69902921
11Systemic lupus erythematosus_Homo sapiens_hsa053222.69794768
12Nucleotide excision repair_Homo sapiens_hsa034202.56584762
13One carbon pool by folate_Homo sapiens_hsa006702.40057164
14RNA degradation_Homo sapiens_hsa030182.00995430
15Ribosome_Homo sapiens_hsa030101.96375602
16p53 signaling pathway_Homo sapiens_hsa041151.94178466
17mRNA surveillance pathway_Homo sapiens_hsa030151.90620419
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.87702474
19RNA polymerase_Homo sapiens_hsa030201.87577875
20Pyrimidine metabolism_Homo sapiens_hsa002401.78460021
21Basal transcription factors_Homo sapiens_hsa030221.67399801
22Protein export_Homo sapiens_hsa030601.63807816
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.58215957
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.53412705
25Viral carcinogenesis_Homo sapiens_hsa052031.46537654
26Herpes simplex infection_Homo sapiens_hsa051681.30239757
27Pyruvate metabolism_Homo sapiens_hsa006201.26047540
28Propanoate metabolism_Homo sapiens_hsa006401.24292708
29Alcoholism_Homo sapiens_hsa050341.20847256
30MicroRNAs in cancer_Homo sapiens_hsa052061.20682575
31Vitamin B6 metabolism_Homo sapiens_hsa007501.19561459
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.18640226
33Proteasome_Homo sapiens_hsa030501.16402933
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.15886017
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14604194
36Folate biosynthesis_Homo sapiens_hsa007901.14112351
37Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.10582565
38Oocyte meiosis_Homo sapiens_hsa041141.10128218
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.09401419
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04443880
41Antigen processing and presentation_Homo sapiens_hsa046121.01558425
42Epstein-Barr virus infection_Homo sapiens_hsa051691.01420405
43Biosynthesis of amino acids_Homo sapiens_hsa012301.00867444
44Small cell lung cancer_Homo sapiens_hsa052221.00084003
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.99576319
46HTLV-I infection_Homo sapiens_hsa051660.96850138
47Primary immunodeficiency_Homo sapiens_hsa053400.96415695
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89491298
49NF-kappa B signaling pathway_Homo sapiens_hsa040640.89013900
50Purine metabolism_Homo sapiens_hsa002300.87235174
51Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84645324
52Steroid biosynthesis_Homo sapiens_hsa001000.80281356
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.80105027
54Fatty acid elongation_Homo sapiens_hsa000620.74026189
55Measles_Homo sapiens_hsa051620.73663112
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.73175622
57Huntingtons disease_Homo sapiens_hsa050160.72047912
58Parkinsons disease_Homo sapiens_hsa050120.71661991
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70637511
60Apoptosis_Homo sapiens_hsa042100.68721240
61Hematopoietic cell lineage_Homo sapiens_hsa046400.68511894
62Hepatitis B_Homo sapiens_hsa051610.66644830
63Thyroid cancer_Homo sapiens_hsa052160.63868805
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63361700
65Lysine degradation_Homo sapiens_hsa003100.62055132
66Colorectal cancer_Homo sapiens_hsa052100.59806003
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59735185
68Chronic myeloid leukemia_Homo sapiens_hsa052200.59311173
69Carbon metabolism_Homo sapiens_hsa012000.57639689
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.55352819
71Influenza A_Homo sapiens_hsa051640.54300441
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53720815
73Oxidative phosphorylation_Homo sapiens_hsa001900.53503999
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52928323
75Pancreatic cancer_Homo sapiens_hsa052120.49403762
76Viral myocarditis_Homo sapiens_hsa054160.49306075
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48882717
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.47379204
79Sulfur relay system_Homo sapiens_hsa041220.47130014
80Legionellosis_Homo sapiens_hsa051340.47080438
81Pentose phosphate pathway_Homo sapiens_hsa000300.46510973
82B cell receptor signaling pathway_Homo sapiens_hsa046620.45924265
83Pathways in cancer_Homo sapiens_hsa052000.45649814
84Notch signaling pathway_Homo sapiens_hsa043300.45476895
85Non-small cell lung cancer_Homo sapiens_hsa052230.45081766
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45028724
87TGF-beta signaling pathway_Homo sapiens_hsa043500.44810753
88Glutathione metabolism_Homo sapiens_hsa004800.44089451
89Selenocompound metabolism_Homo sapiens_hsa004500.43166412
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43160586
91Prostate cancer_Homo sapiens_hsa052150.41775877
92Leishmaniasis_Homo sapiens_hsa051400.41591643
93Basal cell carcinoma_Homo sapiens_hsa052170.41460478
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40407776
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39302894
96Drug metabolism - other enzymes_Homo sapiens_hsa009830.37870246
97Metabolic pathways_Homo sapiens_hsa011000.37150682
98Adherens junction_Homo sapiens_hsa045200.36475750
99mTOR signaling pathway_Homo sapiens_hsa041500.34934766
100Cyanoamino acid metabolism_Homo sapiens_hsa004600.34716752
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.34518806
102Arachidonic acid metabolism_Homo sapiens_hsa005900.34437338
103Fatty acid metabolism_Homo sapiens_hsa012120.34257585
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33892974
105Asthma_Homo sapiens_hsa053100.33170005
106Renin-angiotensin system_Homo sapiens_hsa046140.31926000
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.31240009
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.31066291
109Sulfur metabolism_Homo sapiens_hsa009200.30971038
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30965972
111FoxO signaling pathway_Homo sapiens_hsa040680.30960456
112Acute myeloid leukemia_Homo sapiens_hsa052210.30351402
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29990225
114Hippo signaling pathway_Homo sapiens_hsa043900.29250007
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.28149626
116Autoimmune thyroid disease_Homo sapiens_hsa053200.26890331
117Alzheimers disease_Homo sapiens_hsa050100.26608569
118N-Glycan biosynthesis_Homo sapiens_hsa005100.26389253
119Graft-versus-host disease_Homo sapiens_hsa053320.25361405
120T cell receptor signaling pathway_Homo sapiens_hsa046600.24567199
121Bladder cancer_Homo sapiens_hsa052190.24103991
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23637616
123Regulation of autophagy_Homo sapiens_hsa041400.23528470
124Allograft rejection_Homo sapiens_hsa053300.23117330
125Toxoplasmosis_Homo sapiens_hsa051450.22645180
126Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22602612
127Shigellosis_Homo sapiens_hsa051310.22470642
128Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20173315
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20038035
130Arginine and proline metabolism_Homo sapiens_hsa003300.19889392
131Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.19476520
132Melanoma_Homo sapiens_hsa052180.18365958
133Wnt signaling pathway_Homo sapiens_hsa043100.17794749
134PI3K-Akt signaling pathway_Homo sapiens_hsa041510.17511491
135Proteoglycans in cancer_Homo sapiens_hsa052050.17162834
136Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15152982
137Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.08838723
138Fatty acid biosynthesis_Homo sapiens_hsa000610.07915563
139Butanoate metabolism_Homo sapiens_hsa006500.05089900
140Fatty acid degradation_Homo sapiens_hsa000710.04274418
141Arginine biosynthesis_Homo sapiens_hsa002200.02675941
142Hedgehog signaling pathway_Homo sapiens_hsa043400.00316089
143Peroxisome_Homo sapiens_hsa04146-0.0169885
144Vitamin digestion and absorption_Homo sapiens_hsa04977-0.0130674

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