CARF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)5.05118282
2response to pheromone (GO:0019236)4.82512479
3presynaptic membrane organization (GO:0097090)4.55668214
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.53454671
5daunorubicin metabolic process (GO:0044597)4.10805362
6polyketide metabolic process (GO:0030638)4.10805362
7doxorubicin metabolic process (GO:0044598)4.10805362
8nonmotile primary cilium assembly (GO:0035058)3.99202636
9postsynaptic membrane organization (GO:0001941)3.89272850
10epithelial cilium movement (GO:0003351)3.79251674
11nucleobase catabolic process (GO:0046113)3.71046321
12neural tube formation (GO:0001841)3.61506473
13establishment of protein localization to Golgi (GO:0072600)3.57328549
14detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.44716728
15cornea development in camera-type eye (GO:0061303)3.39534073
16regulation of cilium movement (GO:0003352)3.29614834
17negative regulation of cytosolic calcium ion concentration (GO:0051481)3.28988616
18gamma-aminobutyric acid transport (GO:0015812)3.28949995
19negative regulation of synaptic transmission, GABAergic (GO:0032229)3.27746886
20centriole assembly (GO:0098534)3.25118173
21regulation of male gonad development (GO:2000018)3.24809005
22cilium morphogenesis (GO:0060271)3.22840495
23neuronal action potential propagation (GO:0019227)3.21239264
24pyrimidine nucleobase catabolic process (GO:0006208)3.20151028
25protein targeting to Golgi (GO:0000042)3.17996797
26regulation of pigment cell differentiation (GO:0050932)3.17042747
27developmental pigmentation (GO:0048066)3.13460103
28protein K11-linked deubiquitination (GO:0035871)3.09048877
29startle response (GO:0001964)3.08344493
30behavioral response to nicotine (GO:0035095)3.07254209
31superoxide anion generation (GO:0042554)3.02093784
32protein polyglutamylation (GO:0018095)3.01419990
33piRNA metabolic process (GO:0034587)2.94976388
34neuron cell-cell adhesion (GO:0007158)2.93949048
35behavioral response to ethanol (GO:0048149)2.93803403
36indolalkylamine metabolic process (GO:0006586)2.93798291
37cellular ketone body metabolic process (GO:0046950)2.91660797
38righting reflex (GO:0060013)2.90306692
39facial nerve structural organization (GO:0021612)2.88675599
40retrograde transport, vesicle recycling within Golgi (GO:0000301)2.87589754
41intraciliary transport (GO:0042073)2.87099904
42protein localization to cilium (GO:0061512)2.81540975
43mannosylation (GO:0097502)2.81179133
44regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.80215236
45protein localization to Golgi apparatus (GO:0034067)2.79291708
46neuronal action potential (GO:0019228)2.78814425
47positive regulation of uterine smooth muscle contraction (GO:0070474)2.77157340
48cell differentiation involved in metanephros development (GO:0072202)2.76952181
49negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.76406628
50negative regulation of T-helper cell differentiation (GO:0045623)2.76406628
51cerebral cortex radially oriented cell migration (GO:0021799)2.76060975
52glycosphingolipid biosynthetic process (GO:0006688)2.75952401
53adenosine metabolic process (GO:0046085)2.75813658
54reciprocal DNA recombination (GO:0035825)2.75528209
55reciprocal meiotic recombination (GO:0007131)2.75528209
56mesenchymal cell differentiation involved in renal system development (GO:2001012)2.75525645
57mesenchymal cell differentiation involved in kidney development (GO:0072161)2.75525645
58regulation of germinal center formation (GO:0002634)2.74488619
59retinal cone cell development (GO:0046549)2.73899885
60detection of light stimulus involved in sensory perception (GO:0050962)2.73356146
61detection of light stimulus involved in visual perception (GO:0050908)2.73356146
62glycerophospholipid catabolic process (GO:0046475)2.72013207
63interkinetic nuclear migration (GO:0022027)2.69914058
64cranial nerve structural organization (GO:0021604)2.69555237
65tachykinin receptor signaling pathway (GO:0007217)2.69126635
66negative regulation of neurotransmitter transport (GO:0051589)2.67740819
67negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.66250774
68cellular component assembly involved in morphogenesis (GO:0010927)2.66038536
69negative regulation of neurotransmitter secretion (GO:0046929)2.65860684
70GPI anchor biosynthetic process (GO:0006506)2.65002829
71regulation of timing of cell differentiation (GO:0048505)2.63515326
72retinal rod cell development (GO:0046548)2.63003455
73G-protein coupled receptor internalization (GO:0002031)2.62209268
74lymphoid progenitor cell differentiation (GO:0002320)2.61689617
75ketone body metabolic process (GO:1902224)2.60643219
76positive regulation of cellular amide metabolic process (GO:0034250)2.59754108
77platelet dense granule organization (GO:0060155)2.59378700
78regulation of meiosis I (GO:0060631)2.59090996
79cilium or flagellum-dependent cell motility (GO:0001539)2.58398938
80energy homeostasis (GO:0097009)2.55067763
81serotonin receptor signaling pathway (GO:0007210)2.54929033
82centriole replication (GO:0007099)2.53827312
83regulation of memory T cell differentiation (GO:0043380)2.53610933
84cytochrome complex assembly (GO:0017004)2.52311010
85respiratory chain complex IV assembly (GO:0008535)2.52090949
86GPI anchor metabolic process (GO:0006505)2.51785356
87regulation of telomere maintenance (GO:0032204)2.51427801
88indole-containing compound catabolic process (GO:0042436)2.51338369
89indolalkylamine catabolic process (GO:0046218)2.51338369
90tryptophan catabolic process (GO:0006569)2.51338369
91cyclic nucleotide catabolic process (GO:0009214)2.51048299
92cAMP catabolic process (GO:0006198)2.50112733
93transmission of nerve impulse (GO:0019226)2.49796946
94sympathetic nervous system development (GO:0048485)2.49504614
95negative regulation of homotypic cell-cell adhesion (GO:0034111)2.49375832
96regulation of action potential (GO:0098900)2.49233985
97neurotransmitter-gated ion channel clustering (GO:0072578)2.47910904
98positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.47702388
99positive regulation of protein sumoylation (GO:0033235)2.47184524
100ionotropic glutamate receptor signaling pathway (GO:0035235)2.46612284
101sperm motility (GO:0030317)2.46591478
102short-chain fatty acid metabolic process (GO:0046459)2.45851647
103membrane depolarization during action potential (GO:0086010)2.45499314
104nucleotide transmembrane transport (GO:1901679)2.44929909
105dentate gyrus development (GO:0021542)2.44084542
106negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.44003052
107axoneme assembly (GO:0035082)2.43777479
108axonemal dynein complex assembly (GO:0070286)2.43381252
109positive regulation of meiosis (GO:0045836)2.42395872
110membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.42191691
111inositol phosphate catabolic process (GO:0071545)2.40241363
112cilium assembly (GO:0042384)2.40037237
113kidney morphogenesis (GO:0060993)2.39917693
114activated T cell proliferation (GO:0050798)2.38946792
115regulation of rhodopsin mediated signaling pathway (GO:0022400)2.38850792
116regulation of non-canonical Wnt signaling pathway (GO:2000050)2.38536418
117negative regulation of mast cell activation (GO:0033004)2.38193118
118fucose catabolic process (GO:0019317)2.37401088
119L-fucose metabolic process (GO:0042354)2.37401088
120L-fucose catabolic process (GO:0042355)2.37401088
121G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.37274407
122sulfation (GO:0051923)2.36558513
123positive regulation of developmental pigmentation (GO:0048087)2.36380669
124photoreceptor cell development (GO:0042461)2.35315471
125male meiosis I (GO:0007141)2.35245039
126embryonic epithelial tube formation (GO:0001838)2.35165737
127proline transport (GO:0015824)2.34546277
128preassembly of GPI anchor in ER membrane (GO:0016254)2.34534056
129motile cilium assembly (GO:0044458)2.33943532
130calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.32630668
131detection of mechanical stimulus involved in sensory perception (GO:0050974)2.32097241
132Golgi to endosome transport (GO:0006895)2.32047185
133mesonephros development (GO:0001823)2.31972045
134germinal center formation (GO:0002467)2.31808730
135photoreceptor cell maintenance (GO:0045494)2.31681596
136DNA methylation involved in gamete generation (GO:0043046)2.31063298
137anterograde synaptic vesicle transport (GO:0048490)2.30789926
138reflex (GO:0060004)2.30676805
139positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.29788435
140cilium organization (GO:0044782)2.29264446
141inner ear receptor stereocilium organization (GO:0060122)2.29028075
142androgen biosynthetic process (GO:0006702)2.28640741
143left/right axis specification (GO:0070986)2.28543791
144regulation of platelet aggregation (GO:0090330)2.27862465
145cilium movement (GO:0003341)2.27374558
146generation of neurons (GO:0048699)2.27136020
147C-terminal protein amino acid modification (GO:0018410)2.26530741
148mechanosensory behavior (GO:0007638)2.26432354
149rhodopsin mediated signaling pathway (GO:0016056)2.26154874
150G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.25896921
151aminoglycoside antibiotic metabolic process (GO:0030647)2.25421425
152auditory receptor cell stereocilium organization (GO:0060088)2.24944287
153protein localization to synapse (GO:0035418)2.24453630
154extracellular negative regulation of signal transduction (GO:1900116)2.23907176
155extracellular regulation of signal transduction (GO:1900115)2.23907176
156regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.23787009
157negative regulation of keratinocyte proliferation (GO:0010839)2.22335456
158glutamate receptor signaling pathway (GO:0007215)2.22172308
159natural killer cell activation involved in immune response (GO:0002323)2.22041918
160protein heterotetramerization (GO:0051290)2.21705270
161regulation of synaptic transmission, GABAergic (GO:0032228)2.21313597
162regulation of uterine smooth muscle contraction (GO:0070472)2.20752267
163eye photoreceptor cell development (GO:0042462)2.20659951
164positive regulation of synapse assembly (GO:0051965)2.20332337
165synaptic transmission, glutamatergic (GO:0035249)2.20170959
166sleep (GO:0030431)2.19863392
167C-terminal protein lipidation (GO:0006501)2.19840637
168microtubule depolymerization (GO:0007019)2.18467698
169negative regulation of systemic arterial blood pressure (GO:0003085)2.18453280
170definitive hemopoiesis (GO:0060216)2.18406865

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.13213434
2EZH2_22144423_ChIP-Seq_EOC_Human3.70136129
3ZFP57_27257070_Chip-Seq_ESCs_Mouse2.93828976
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.79723115
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.73261131
6ZNF274_21170338_ChIP-Seq_K562_Hela2.57339321
7* PCGF2_27294783_Chip-Seq_ESCs_Mouse2.56737245
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.47431406
9TAF15_26573619_Chip-Seq_HEK293_Human2.46378366
10* FLI1_27457419_Chip-Seq_LIVER_Mouse2.41163641
11* SUZ12_27294783_Chip-Seq_NPCs_Mouse2.13507067
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.09890871
13IGF1R_20145208_ChIP-Seq_DFB_Human2.07328727
14P300_19829295_ChIP-Seq_ESCs_Human2.06906456
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.04041535
16* NFE2_27457419_Chip-Seq_LIVER_Mouse2.02615624
17FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.99698624
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.96990814
19* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.89298810
20FUS_26573619_Chip-Seq_HEK293_Human1.88848677
21SMAD_19615063_ChIP-ChIP_OVARY_Human1.87481186
22* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.86550293
23NANOG_18555785_Chip-Seq_ESCs_Mouse1.86498928
24* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.84009781
25* EZH2_27294783_Chip-Seq_NPCs_Mouse1.83266583
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.82803913
27CBX2_27304074_Chip-Seq_ESCs_Mouse1.81662768
28JARID2_20064375_ChIP-Seq_MESCs_Mouse1.81276782
29* P53_22387025_ChIP-Seq_ESCs_Mouse1.81127411
30BP1_19119308_ChIP-ChIP_Hs578T_Human1.80177515
31SUZ12_18555785_Chip-Seq_ESCs_Mouse1.79495023
32* E2F1_18555785_Chip-Seq_ESCs_Mouse1.78010292
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.77661849
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.77337858
35* STAT3_18555785_Chip-Seq_ESCs_Mouse1.75590555
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.75136185
37VDR_22108803_ChIP-Seq_LS180_Human1.71597673
38BCAT_22108803_ChIP-Seq_LS180_Human1.71023416
39SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.70844778
40RNF2_27304074_Chip-Seq_NSC_Mouse1.69495478
41SMAD4_21799915_ChIP-Seq_A2780_Human1.68736542
42EZH2_27304074_Chip-Seq_ESCs_Mouse1.67846363
43* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.64785107
44EED_16625203_ChIP-ChIP_MESCs_Mouse1.64501621
45* P300_18555785_Chip-Seq_ESCs_Mouse1.64421197
46* CMYC_18555785_Chip-Seq_ESCs_Mouse1.64087234
47AR_21572438_ChIP-Seq_LNCaP_Human1.61381385
48* NMYC_18555785_Chip-Seq_ESCs_Mouse1.61312458
49* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.60234223
50EWS_26573619_Chip-Seq_HEK293_Human1.58795101
51PIAS1_25552417_ChIP-Seq_VCAP_Human1.55825286
52ER_23166858_ChIP-Seq_MCF-7_Human1.55393025
53CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55044187
54CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54239373
55CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52361758
56* SOX2_18555785_Chip-Seq_ESCs_Mouse1.52219589
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51325017
58CBP_20019798_ChIP-Seq_JUKART_Human1.51325017
59SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.50050198
60* OCT4_18555785_Chip-Seq_ESCs_Mouse1.49913143
61SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.48768171
62TAL1_26923725_Chip-Seq_HPCs_Mouse1.45590767
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.45086327
64CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42283176
65* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.42195024
66* PU1_27457419_Chip-Seq_LIVER_Mouse1.40435203
67SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.38717400
68* KLF4_18555785_Chip-Seq_ESCs_Mouse1.38340727
69* ZFX_18555785_Chip-Seq_ESCs_Mouse1.37411234
70BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36826954
71* SMAD1_18555785_Chip-Seq_ESCs_Mouse1.35069516
72OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34945937
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34606966
74ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32489882
75STAT3_23295773_ChIP-Seq_U87_Human1.32178658
76* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.31632147
77JARID2_20075857_ChIP-Seq_MESCs_Mouse1.31186344
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30901453
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30326919
80PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.30300097
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.29422170
82* CTCF_18555785_Chip-Seq_ESCs_Mouse1.29129772
83* CRX_20693478_ChIP-Seq_RETINA_Mouse1.28417251
84* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28396433
85TCF4_23295773_ChIP-Seq_U87_Human1.27742078
86PRDM14_20953172_ChIP-Seq_ESCs_Human1.27540781
87TCF4_22108803_ChIP-Seq_LS180_Human1.27377417
88CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27364829
89EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26125367
90SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.25991268
91* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25602682
92RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25391202
93PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.24634866
94HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.24598234
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23774083
96RUNX2_22187159_ChIP-Seq_PCA_Human1.23750788
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23622652
98IRF1_19129219_ChIP-ChIP_H3396_Human1.23407511
99RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22420585
100* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.21682339
101KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19844335
102NANOG_19829295_ChIP-Seq_ESCs_Human1.19536696
103SOX2_19829295_ChIP-Seq_ESCs_Human1.19536696
104KDM2B_26808549_Chip-Seq_REH_Human1.18653457
105SOX2_21211035_ChIP-Seq_LN229_Gbm1.18616665
106TP53_22573176_ChIP-Seq_HFKS_Human1.18031012
107AR_25329375_ChIP-Seq_VCAP_Human1.17907389
108EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17641058
109RNF2_27304074_Chip-Seq_ESCs_Mouse1.16535226
110TP53_18474530_ChIP-ChIP_U2OS_Human1.16344998
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16193579
112EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16043934
113RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16043934
114VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14481561
115* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.14072120
116MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.13654644
117POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13580772
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13580772
119FOXA1_21572438_ChIP-Seq_LNCaP_Human1.13392613
120LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12634653
121ARNT_22903824_ChIP-Seq_MCF-7_Human1.12260386
122EZH2_27294783_Chip-Seq_ESCs_Mouse1.11660224
123POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10925409
124SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.09274327
125LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08441907
126TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07530761
127REST_21632747_ChIP-Seq_MESCs_Mouse1.07144024
128NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06075255
129SMAD4_21741376_ChIP-Seq_EPCs_Human1.05304971
130TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.04131717
131CDX2_22108803_ChIP-Seq_LS180_Human1.01479165
132TP53_16413492_ChIP-PET_HCT116_Human1.01264482
133GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00723898
134AHR_22903824_ChIP-Seq_MCF-7_Human0.98882650

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001188_hyperpigmentation4.73480689
2MP0006292_abnormal_olfactory_placode3.45086451
3MP0003880_abnormal_central_pattern3.24344495
4MP0005409_darkened_coat_color3.20754918
5MP0000015_abnormal_ear_pigmentation2.97229362
6MP0003136_yellow_coat_color2.93443204
7MP0005646_abnormal_pituitary_gland2.69889603
8MP0005645_abnormal_hypothalamus_physiol2.61975522
9MP0002653_abnormal_ependyma_morphology2.52541069
10MP0001986_abnormal_taste_sensitivity2.52253758
11MP0000566_synostosis2.50490006
12MP0005174_abnormal_tail_pigmentation2.43507552
13MP0002876_abnormal_thyroid_physiology2.42967676
14MP0005171_absent_coat_pigmentation2.41018192
15MP0004885_abnormal_endolymph2.20404935
16MP0003787_abnormal_imprinting2.11889481
17MP0002638_abnormal_pupillary_reflex1.93012680
18MP0000427_abnormal_hair_cycle1.90550908
19MP0001486_abnormal_startle_reflex1.88962195
20MP0002102_abnormal_ear_morphology1.85917960
21MP0002837_dystrophic_cardiac_calcinosis1.85336432
22MP0000372_irregular_coat_pigmentation1.78675231
23MP0001984_abnormal_olfaction1.75228488
24MP0005075_abnormal_melanosome_morpholog1.72624172
25MP0004381_abnormal_hair_follicle1.69003628
26MP0002095_abnormal_skin_pigmentation1.66578812
27MP0009745_abnormal_behavioral_response1.65747976
28MP0000569_abnormal_digit_pigmentation1.55213287
29MP0004043_abnormal_pH_regulation1.54534808
30MP0009046_muscle_twitch1.53549024
31MP0001968_abnormal_touch/_nociception1.52163218
32MP0000383_abnormal_hair_follicle1.50405174
33MP0006072_abnormal_retinal_apoptosis1.49837065
34MP0002272_abnormal_nervous_system1.49341327
35MP0009697_abnormal_copulation1.49173804
36MP0002277_abnormal_respiratory_mucosa1.48821264
37MP0003195_calcinosis1.43228168
38MP0002736_abnormal_nociception_after1.41369195
39MP0005379_endocrine/exocrine_gland_phen1.41310338
40MP0000631_abnormal_neuroendocrine_gland1.38669538
41MP0000681_abnormal_thyroid_gland1.38112494
42MP0004142_abnormal_muscle_tone1.37417831
43MP0005551_abnormal_eye_electrophysiolog1.36902712
44MP0004147_increased_porphyrin_level1.36813283
45MP0003283_abnormal_digestive_organ1.35549307
46MP0002909_abnormal_adrenal_gland1.35224170
47MP0002572_abnormal_emotion/affect_behav1.35063513
48MP0008872_abnormal_physiological_respon1.32982089
49MP0006276_abnormal_autonomic_nervous1.32246795
50MP0009379_abnormal_foot_pigmentation1.31332505
51MP0003635_abnormal_synaptic_transmissio1.31104314
52MP0002067_abnormal_sensory_capabilities1.30032151
53MP0002735_abnormal_chemical_nociception1.29998977
54MP0008058_abnormal_DNA_repair1.29855442
55MP0005389_reproductive_system_phenotype1.25143219
56MP0008260_abnormal_autophagy1.24927052
57MP0005423_abnormal_somatic_nervous1.24424330
58MP0003646_muscle_fatigue1.24156530
59MP0001502_abnormal_circadian_rhythm1.24141162
60MP0004742_abnormal_vestibular_system1.20513286
61MP0004133_heterotaxia1.18865660
62MP0001905_abnormal_dopamine_level1.18864145
63MP0001501_abnormal_sleep_pattern1.18376683
64MP0002734_abnormal_mechanical_nocicepti1.17107043
65MP0000516_abnormal_urinary_system1.16667979
66MP0005367_renal/urinary_system_phenotyp1.16667979
67MP0002148_abnormal_hypersensitivity_rea1.15746225
68MP0002064_seizures1.14561688
69MP0010386_abnormal_urinary_bladder1.13858610
70MP0005671_abnormal_response_to1.13592563
71MP0000026_abnormal_inner_ear1.12807817
72MP0001835_abnormal_antigen_presentation1.10409171
73MP0002733_abnormal_thermal_nociception1.10293558
74MP0002557_abnormal_social/conspecific_i1.10180317
75MP0001963_abnormal_hearing_physiology1.08213957
76MP0003698_abnormal_male_reproductive1.06502109
77MP0001529_abnormal_vocalization1.06366720
78MP0003724_increased_susceptibility_to1.06297758
79MP0002229_neurodegeneration1.04962606
80MP0002163_abnormal_gland_morphology1.03536277
81* MP0002063_abnormal_learning/memory/cond1.03458499
82MP0003122_maternal_imprinting1.02604942
83MP0008789_abnormal_olfactory_epithelium1.01761834
84MP0002132_abnormal_respiratory_system1.01000402
85MP0005253_abnormal_eye_physiology1.00708574
86MP0005167_abnormal_blood-brain_barrier1.00180799
87MP0002177_abnormal_outer_ear1.00165135
88MP0001919_abnormal_reproductive_system0.98948569
89MP0004270_analgesia0.98034067
90MP0004859_abnormal_synaptic_plasticity0.97247551
91MP0002928_abnormal_bile_duct0.96592092
92MP0000678_abnormal_parathyroid_gland0.95536929
93MP0002751_abnormal_autonomic_nervous0.95429916
94MP0002693_abnormal_pancreas_physiology0.95166555
95MP0002938_white_spotting0.95107040
96MP0003941_abnormal_skin_development0.95100086
97MP0008995_early_reproductive_senescence0.95054066
98MP0008877_abnormal_DNA_methylation0.94594238
99MP0003633_abnormal_nervous_system0.94441669
100MP0002822_catalepsy0.91408218
101MP0001485_abnormal_pinna_reflex0.90869906
102MP0000778_abnormal_nervous_system0.90368774
103MP0004085_abnormal_heartbeat0.90123450
104MP0000049_abnormal_middle_ear0.88857601
105MP0005394_taste/olfaction_phenotype0.88783633
106MP0005499_abnormal_olfactory_system0.88783633
107MP0001186_pigmentation_phenotype0.87597657
108MP0001944_abnormal_pancreas_morphology0.87521642
109MP0002882_abnormal_neuron_morphology0.86981831
110MP0003183_abnormal_peptide_metabolism0.85083241
111MP0004215_abnormal_myocardial_fiber0.84809790
112MP0002184_abnormal_innervation0.84562702
113MP0009785_altered_susceptibility_to0.83478529
114MP0004145_abnormal_muscle_electrophysio0.82809795
115MP0009780_abnormal_chondrocyte_physiolo0.81403645
116MP0002160_abnormal_reproductive_system0.81274668
117MP0005084_abnormal_gallbladder_morpholo0.81172824
118MP0001929_abnormal_gametogenesis0.80986012
119MP0001764_abnormal_homeostasis0.80821651
120MP0008775_abnormal_heart_ventricle0.80739522
121MP0000013_abnormal_adipose_tissue0.80514397
122MP0003879_abnormal_hair_cell0.80479654
123MP0008569_lethality_at_weaning0.79943639
124MP0000230_abnormal_systemic_arterial0.79632333
125MP0001970_abnormal_pain_threshold0.77414891
126MP0005410_abnormal_fertilization0.76088253
127MP0001324_abnormal_eye_pigmentation0.74624841
128MP0001177_atelectasis0.73856597
129MP0003938_abnormal_ear_development0.73584643
130MP0002075_abnormal_coat/hair_pigmentati0.73182361
131MP0004924_abnormal_behavior0.73072860
132MP0005386_behavior/neurological_phenoty0.73072860
133MP0002752_abnormal_somatic_nervous0.70792937
134MP0002009_preneoplasia0.70081782
135MP0004782_abnormal_surfactant_physiolog0.69457082
136MP0003786_premature_aging0.69340203
137MP0002396_abnormal_hematopoietic_system0.68914216
138MP0004134_abnormal_chest_morphology0.68119589
139MP0003121_genomic_imprinting0.67275785
140MP0001440_abnormal_grooming_behavior0.66483745

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.14463527
2Abnormality of the renal cortex (HP:0011035)3.75797970
3Febrile seizures (HP:0002373)3.74473273
4Chromsome breakage (HP:0040012)3.66344787
5Hypothermia (HP:0002045)3.64276983
6Abnormal ciliary motility (HP:0012262)3.43765806
7Abnormal hair whorl (HP:0010721)3.42266547
8Focal motor seizures (HP:0011153)3.33559319
9True hermaphroditism (HP:0010459)3.31265374
10Type I transferrin isoform profile (HP:0003642)3.22050503
11Dynein arm defect of respiratory motile cilia (HP:0012255)3.20380069
12Absent/shortened dynein arms (HP:0200106)3.20380069
13Abnormal respiratory motile cilium physiology (HP:0012261)3.02178977
14Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.98258183
15Progressive cerebellar ataxia (HP:0002073)2.94545049
16Pancreatic fibrosis (HP:0100732)2.94223208
17Abnormal respiratory motile cilium morphology (HP:0005938)2.89961190
18Abnormal respiratory epithelium morphology (HP:0012253)2.89961190
19Thyroid-stimulating hormone excess (HP:0002925)2.84745685
20Cystic liver disease (HP:0006706)2.81900448
21Abnormality of the renal collecting system (HP:0004742)2.80416641
22Duplicated collecting system (HP:0000081)2.77028428
23Tubulointerstitial nephritis (HP:0001970)2.76348593
24Abnormal drinking behavior (HP:0030082)2.73413511
25Polydipsia (HP:0001959)2.73413511
26Reduced antithrombin III activity (HP:0001976)2.73206137
27Vaginal atresia (HP:0000148)2.72901572
28Medial flaring of the eyebrow (HP:0010747)2.66279810
29Patchy hypopigmentation of hair (HP:0011365)2.65538816
30White forelock (HP:0002211)2.62391882
31Genetic anticipation (HP:0003743)2.58802049
32Tubular atrophy (HP:0000092)2.58063346
33Absent speech (HP:0001344)2.57822225
34Absent rod-and cone-mediated responses on ERG (HP:0007688)2.52622974
35Abnormality of incisor morphology (HP:0011063)2.48940452
36Abnormal biliary tract physiology (HP:0012439)2.45406130
37Bile duct proliferation (HP:0001408)2.45406130
38Broad-based gait (HP:0002136)2.44475069
39Epileptic encephalopathy (HP:0200134)2.41656845
40Drooling (HP:0002307)2.37884987
41Widely spaced teeth (HP:0000687)2.37720280
42Nephrogenic diabetes insipidus (HP:0009806)2.36233213
43Decreased central vision (HP:0007663)2.35289129
44Type 2 muscle fiber atrophy (HP:0003554)2.34106805
45Chronic hepatic failure (HP:0100626)2.33555703
46Protruding tongue (HP:0010808)2.33239015
47Attenuation of retinal blood vessels (HP:0007843)2.30807476
48Thyroiditis (HP:0100646)2.30747282
49Tubulointerstitial abnormality (HP:0001969)2.27385481
50Furrowed tongue (HP:0000221)2.26433062
51Pancreatic cysts (HP:0001737)2.25488383
52Type II lissencephaly (HP:0007260)2.24920716
53Median cleft lip (HP:0000161)2.24052776
54Hemiparesis (HP:0001269)2.22755419
55Nonprogressive disorder (HP:0003680)2.22058471
56Congenital primary aphakia (HP:0007707)2.20572994
57Abnormality of the columella (HP:0009929)2.18912507
58Gait imbalance (HP:0002141)2.18702966
59Nephronophthisis (HP:0000090)2.18604838
60Molar tooth sign on MRI (HP:0002419)2.18252158
61Abnormality of midbrain morphology (HP:0002418)2.18252158
62Optic nerve hypoplasia (HP:0000609)2.17839363
63Excessive salivation (HP:0003781)2.17783835
64Stomach cancer (HP:0012126)2.16603568
65Intestinal atresia (HP:0011100)2.15316440
66Septo-optic dysplasia (HP:0100842)2.15153581
67Large for gestational age (HP:0001520)2.13596668
68Volvulus (HP:0002580)2.13219008
69Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.13172363
70Abnormal protein N-linked glycosylation (HP:0012347)2.13172363
71Abnormal protein glycosylation (HP:0012346)2.13172363
72Abnormal glycosylation (HP:0012345)2.13172363
73Anencephaly (HP:0002323)2.12703403
74Preaxial hand polydactyly (HP:0001177)2.12702224
75Clubbing of toes (HP:0100760)2.12513478
76Abnormality of DNA repair (HP:0003254)2.12186765
77Congenital stationary night blindness (HP:0007642)2.12047435
78Prostate neoplasm (HP:0100787)2.10894657
79Abnormal rod and cone electroretinograms (HP:0008323)2.10732050
80Focal seizures (HP:0007359)2.09738631
81Congenital sensorineural hearing impairment (HP:0008527)2.07922806
82Occipital encephalocele (HP:0002085)2.07849377
83Polyuria (HP:0000103)2.07060029
84Abnormality of the preputium (HP:0100587)2.06918240
85Aplasia/Hypoplasia of the fovea (HP:0008060)2.06883109
86Hypoplasia of the fovea (HP:0007750)2.06883109
87Rhinitis (HP:0012384)2.03124126
88Fair hair (HP:0002286)2.03026654
89Alveolar cell carcinoma (HP:0006519)2.02536850
90Renal cortical cysts (HP:0000803)2.02456221
91Generalized hypopigmentation of hair (HP:0011358)2.02225290
923-Methylglutaconic aciduria (HP:0003535)1.99761368
93Postaxial hand polydactyly (HP:0001162)1.99480258
94Postaxial foot polydactyly (HP:0001830)1.99308357
95Dialeptic seizures (HP:0011146)1.98879961
96Abnormality of the renal medulla (HP:0100957)1.98599829
97Polyphagia (HP:0002591)1.97645247
98Gaze-evoked nystagmus (HP:0000640)1.96970880
99Sclerocornea (HP:0000647)1.95395507
100Absent eyebrow (HP:0002223)1.93922311
101Atonic seizures (HP:0010819)1.92138646
102Abolished electroretinogram (ERG) (HP:0000550)1.91752985
103Short foot (HP:0001773)1.89275743
104Aplasia/Hypoplasia of the uvula (HP:0010293)1.88866158
105Male pseudohermaphroditism (HP:0000037)1.86617927
106Optic neuritis (HP:0100653)1.85497926
107Retrobulbar optic neuritis (HP:0100654)1.85497926
108Nephroblastoma (Wilms tumor) (HP:0002667)1.85063740
109Narrow forehead (HP:0000341)1.85055953
110Congenital hepatic fibrosis (HP:0002612)1.83791594
111Microvesicular hepatic steatosis (HP:0001414)1.83676371
112Hyperventilation (HP:0002883)1.83660499
113Tented upper lip vermilion (HP:0010804)1.83532715
114Ectopic kidney (HP:0000086)1.82895108
115Aplasia/Hypoplasia of the tibia (HP:0005772)1.82557985
116Specific learning disability (HP:0001328)1.82386069
117Tubulointerstitial fibrosis (HP:0005576)1.82299782
118Abnormality of the lacrimal duct (HP:0011481)1.81892687
119Inability to walk (HP:0002540)1.81074529
120Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80420370
121Degeneration of the lateral corticospinal tracts (HP:0002314)1.80420370
122Meckel diverticulum (HP:0002245)1.80040251
123Dry hair (HP:0011359)1.79627383
124Nasolacrimal duct obstruction (HP:0000579)1.79113214
125Abnormality of the nasolacrimal system (HP:0000614)1.78278947
126Ketoacidosis (HP:0001993)1.77767289
127Oligodactyly (hands) (HP:0001180)1.77218653
128Aplasia/Hypoplasia of the lens (HP:0008063)1.77124701
129Hypoplastic ischia (HP:0003175)1.75885607
130Dyschromatopsia (HP:0007641)1.75515661
131Embryonal renal neoplasm (HP:0011794)1.74491251
132Abnormality of the axillary hair (HP:0100134)1.74233227
133Abnormality of secondary sexual hair (HP:0009888)1.74233227
134Progressive inability to walk (HP:0002505)1.73209679
135Absent septum pellucidum (HP:0001331)1.72746994
136Bronchiectasis (HP:0002110)1.72174151
137Osteomalacia (HP:0002749)1.72138518
138Genital tract atresia (HP:0001827)1.71840398
139Papilledema (HP:0001085)1.71398408
140Abnormality of the ileum (HP:0001549)1.70971341
141Abnormality of the nasal septum (HP:0000419)1.70244970
142Poor coordination (HP:0002370)1.69984661
143Severe visual impairment (HP:0001141)1.69803845
144Lissencephaly (HP:0001339)1.69433371
145Submucous cleft hard palate (HP:0000176)1.69118622
146Aplasia/Hypoplasia of the tongue (HP:0010295)1.69083775
147Parakeratosis (HP:0001036)1.67903745
148Keratoconus (HP:0000563)1.67775160
149Increased corneal curvature (HP:0100692)1.67775160
150Tachypnea (HP:0002789)1.67678992
151Decreased circulating renin level (HP:0003351)1.66630370
152Aplasia/Hypoplasia of the spleen (HP:0010451)1.65285548
153Astigmatism (HP:0000483)1.64755645
154Asplenia (HP:0001746)1.64201800
155Stage 5 chronic kidney disease (HP:0003774)1.64039304
156Cerebellar dysplasia (HP:0007033)1.63617552

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.61724118
2CASK4.73329958
3TNIK4.49980078
4PRPF4B3.19267553
5MUSK3.16954394
6MKNK22.52596852
7SIK32.50101378
8MAP2K72.48426427
9MAP4K22.43462773
10STK162.39300153
11WNK32.31586816
12STK392.16975076
13TAOK32.15718604
14AKT32.14493142
15MAP3K142.10770722
16WNK42.07632152
17YES11.92726920
18IRAK41.91766223
19ZAK1.87229539
20NUAK11.83560235
21TXK1.81330201
22DAPK21.78576199
23BMPR1B1.74411825
24ADRBK21.72890924
25NEK61.64744458
26FGFR21.64555929
27BMPR21.64330643
28MKNK11.61792857
29SGK21.61217016
30MAPK131.52236841
31MAP2K61.50379257
32IRAK31.49432614
33INSRR1.46774402
34EIF2AK21.46742471
35CDK31.35804569
36ACVR1B1.34898176
37GRK71.26626927
38NTRK31.24638474
39SRPK11.23439791
40PAK31.21031145
41TEC1.17572478
42GRK11.13374257
43NLK1.11388161
44IRAK11.09439234
45PNCK1.08076349
46PHKG11.06797355
47PHKG21.06797355
48BCR1.06658153
49SGK4941.05188799
50SGK2231.05188799
51PTK2B1.00143767
52VRK10.95042934
53CLK10.93311821
54RIPK40.91430807
55EPHA40.89213776
56CAMKK20.86402357
57ERBB30.86271677
58MAP3K120.84826746
59BLK0.84662189
60IRAK20.82677479
61WNK10.81548831
62CCNB10.80932002
63IKBKB0.77498945
64SGK30.76638307
65TRIM280.76535154
66MAP2K40.74999059
67TIE10.74616265
68PLK20.74324518
69UHMK10.74119005
70STK240.72758468
71KIT0.72601602
72EIF2AK30.70567165
73IKBKE0.70387533
74TNK20.69595881
75MAPK150.69540975
76FES0.69241106
77PKN10.69150552
78STK110.68223618
79CDK80.67249393
80ADRBK10.66951574
81BRD40.66304218
82CAMK10.65659238
83CSNK1G20.64924363
84PRKCE0.64820805
85OXSR10.64589374
86RPS6KA40.64533709
87PIK3CA0.62167275
88FGFR30.58136074
89EPHA30.55886514
90MARK10.55349483
91NTRK20.55265475
92MAP3K70.52975414
93PIK3CG0.50178512
94MAPK70.49382259
95BRAF0.48822963
96CDK190.48572282
97MAPKAPK50.47886106
98PRKAA10.47075418
99MAP3K130.46906617
100TGFBR10.46074821
101PRKAA20.45904834
102ITK0.45849373
103DYRK1A0.44299451
104PRKG10.43871577
105SGK10.43504991
106CAMK2A0.43062239
107LYN0.42801082
108CSNK1D0.41578387
109TRPM70.41567158
110PINK10.41149131
111CAMK40.40089479
112PRKCG0.40033977
113CAMK2B0.39805801
114CAMK1G0.39164690
115RPS6KA50.38654729
116PLK40.38611293
117MAP3K40.37998082
118CSNK1G30.37474381
119SYK0.37021357
120CDK50.36695950
121OBSCN0.34776450
122CSNK1A1L0.34707302
123RPS6KB10.34577148
124STK30.34558515
125FER0.34472595
126CHUK0.33273882
127PRKCH0.33208970
128CSNK1A10.32923774
129STK38L0.32217720
130BRSK20.31598060
131DYRK20.31563839
132CSNK1G10.31163540
133TLK10.29399574
134SIK20.29193137
135PRKACA0.28673444
136TAOK20.27043096
137BTK0.27012946
138PRKCQ0.26111395

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.79556834
2Phototransduction_Homo sapiens_hsa047442.75443042
3Butanoate metabolism_Homo sapiens_hsa006502.63450873
4Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.20601298
5Fanconi anemia pathway_Homo sapiens_hsa034602.13001957
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.05784733
7Linoleic acid metabolism_Homo sapiens_hsa005912.03877682
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.00849148
9Propanoate metabolism_Homo sapiens_hsa006401.98498305
10Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.96129521
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.90642840
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.89215955
13Morphine addiction_Homo sapiens_hsa050321.87371849
14SNARE interactions in vesicular transport_Homo sapiens_hsa041301.74714144
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.73569223
16Autoimmune thyroid disease_Homo sapiens_hsa053201.72333557
17Taste transduction_Homo sapiens_hsa047421.71101215
18Serotonergic synapse_Homo sapiens_hsa047261.69571889
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66761483
20Nitrogen metabolism_Homo sapiens_hsa009101.65891214
21Protein export_Homo sapiens_hsa030601.65647997
22ABC transporters_Homo sapiens_hsa020101.61966760
23Allograft rejection_Homo sapiens_hsa053301.59799848
24Dorso-ventral axis formation_Homo sapiens_hsa043201.58956870
25Olfactory transduction_Homo sapiens_hsa047401.56090278
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.52199149
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52064604
28Rheumatoid arthritis_Homo sapiens_hsa053231.46305134
29Graft-versus-host disease_Homo sapiens_hsa053321.46101119
30Basal transcription factors_Homo sapiens_hsa030221.45090797
31Sphingolipid metabolism_Homo sapiens_hsa006001.42895864
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.36918808
33Circadian entrainment_Homo sapiens_hsa047131.36745706
34Glutamatergic synapse_Homo sapiens_hsa047241.36514502
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.34482745
36Homologous recombination_Homo sapiens_hsa034401.32627624
37Non-homologous end-joining_Homo sapiens_hsa034501.30830714
38Fatty acid biosynthesis_Homo sapiens_hsa000611.29713665
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.28309725
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.26694467
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.21728171
42Steroid hormone biosynthesis_Homo sapiens_hsa001401.20987946
43Peroxisome_Homo sapiens_hsa041461.16923052
44Calcium signaling pathway_Homo sapiens_hsa040201.16309491
45Tryptophan metabolism_Homo sapiens_hsa003801.15833295
46GABAergic synapse_Homo sapiens_hsa047271.14672748
47Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.14169588
48Selenocompound metabolism_Homo sapiens_hsa004501.13425005
49Type I diabetes mellitus_Homo sapiens_hsa049401.13088359
50Asthma_Homo sapiens_hsa053101.12527256
51Arachidonic acid metabolism_Homo sapiens_hsa005901.11968943
52Hematopoietic cell lineage_Homo sapiens_hsa046401.10139911
53Collecting duct acid secretion_Homo sapiens_hsa049661.08748648
54NF-kappa B signaling pathway_Homo sapiens_hsa040641.08429195
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.04114358
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02953133
57Primary bile acid biosynthesis_Homo sapiens_hsa001201.01745943
58Measles_Homo sapiens_hsa051620.97740006
59Amphetamine addiction_Homo sapiens_hsa050310.96316117
60Primary immunodeficiency_Homo sapiens_hsa053400.96114687
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94360539
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93383788
63Caffeine metabolism_Homo sapiens_hsa002320.90640639
64Circadian rhythm_Homo sapiens_hsa047100.90035108
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88329468
66Ether lipid metabolism_Homo sapiens_hsa005650.88315759
67Regulation of autophagy_Homo sapiens_hsa041400.86741620
68Purine metabolism_Homo sapiens_hsa002300.85621972
69Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84837479
70Long-term depression_Homo sapiens_hsa047300.84662588
71Synaptic vesicle cycle_Homo sapiens_hsa047210.84345831
72Chemical carcinogenesis_Homo sapiens_hsa052040.81561100
73African trypanosomiasis_Homo sapiens_hsa051430.81233254
74Other glycan degradation_Homo sapiens_hsa005110.81001517
75Insulin secretion_Homo sapiens_hsa049110.80921130
76Base excision repair_Homo sapiens_hsa034100.79630439
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.79381066
78Cholinergic synapse_Homo sapiens_hsa047250.79010939
79RNA degradation_Homo sapiens_hsa030180.75640062
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74196456
81Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73918103
82beta-Alanine metabolism_Homo sapiens_hsa004100.72671050
83Retinol metabolism_Homo sapiens_hsa008300.71881677
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71018602
85Salivary secretion_Homo sapiens_hsa049700.70450477
86Oxidative phosphorylation_Homo sapiens_hsa001900.69929869
87NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69560661
88cAMP signaling pathway_Homo sapiens_hsa040240.68854026
89Dopaminergic synapse_Homo sapiens_hsa047280.68789979
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68652355
91Nucleotide excision repair_Homo sapiens_hsa034200.68333531
92Renin secretion_Homo sapiens_hsa049240.66667554
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.65555075
94Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65215891
95Oxytocin signaling pathway_Homo sapiens_hsa049210.64702227
96Cocaine addiction_Homo sapiens_hsa050300.64583899
97Jak-STAT signaling pathway_Homo sapiens_hsa046300.64430308
98Glycerolipid metabolism_Homo sapiens_hsa005610.64284741
99Hedgehog signaling pathway_Homo sapiens_hsa043400.63303324
100RNA polymerase_Homo sapiens_hsa030200.62454227
101Malaria_Homo sapiens_hsa051440.61796563
102Phagosome_Homo sapiens_hsa041450.61134175
103Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60594658
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.60380240
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59647642
106Long-term potentiation_Homo sapiens_hsa047200.58999255
107Chemokine signaling pathway_Homo sapiens_hsa040620.57531696
108Type II diabetes mellitus_Homo sapiens_hsa049300.57321894
109Vibrio cholerae infection_Homo sapiens_hsa051100.56950562
110Herpes simplex infection_Homo sapiens_hsa051680.55310914
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55091668
112Ovarian steroidogenesis_Homo sapiens_hsa049130.53153273
113Leishmaniasis_Homo sapiens_hsa051400.51751727
114Influenza A_Homo sapiens_hsa051640.51272805
115Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51067461
116Huntingtons disease_Homo sapiens_hsa050160.50446836
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.50333512
118Ras signaling pathway_Homo sapiens_hsa040140.50031666
119Melanoma_Homo sapiens_hsa052180.49833140
120N-Glycan biosynthesis_Homo sapiens_hsa005100.48684634
121Fatty acid metabolism_Homo sapiens_hsa012120.48614187
122Axon guidance_Homo sapiens_hsa043600.48119885
123Mismatch repair_Homo sapiens_hsa034300.47919467
124Inositol phosphate metabolism_Homo sapiens_hsa005620.47724239
125Fatty acid elongation_Homo sapiens_hsa000620.46914100
126Wnt signaling pathway_Homo sapiens_hsa043100.46110931
127Alzheimers disease_Homo sapiens_hsa050100.46014727
128cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45921494
129Pyrimidine metabolism_Homo sapiens_hsa002400.45903098
130Tuberculosis_Homo sapiens_hsa051520.44054217
131Gastric acid secretion_Homo sapiens_hsa049710.43061860
132Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.41934215
133Alcoholism_Homo sapiens_hsa050340.41930720
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.39109505
135Basal cell carcinoma_Homo sapiens_hsa052170.39052311
136Pancreatic secretion_Homo sapiens_hsa049720.38714652
137Pertussis_Homo sapiens_hsa051330.38634424
138TGF-beta signaling pathway_Homo sapiens_hsa043500.38518530
139Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37327118
140Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37299673
141Histidine metabolism_Homo sapiens_hsa003400.36980493
142Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35785369
143Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32905133
144Cardiac muscle contraction_Homo sapiens_hsa042600.31252582

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