CALD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chondrocyte proliferation (GO:0035988)5.83957790
2collagen fibril organization (GO:0030199)5.38621460
3cell adhesion mediated by integrin (GO:0033627)4.75907067
4endodermal cell differentiation (GO:0035987)4.67068619
5sequestering of extracellular ligand from receptor (GO:0035581)4.50110654
6epoxygenase P450 pathway (GO:0019373)4.45633694
7positive regulation of endothelial cell apoptotic process (GO:2000353)4.45223199
8protein heterotrimerization (GO:0070208)4.33272120
9negative regulation of fibrinolysis (GO:0051918)4.30223633
10regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.28208233
11bone trabecula formation (GO:0060346)4.16543055
12neuron projection extension involved in neuron projection guidance (GO:1902284)4.01779594
13axon extension involved in axon guidance (GO:0048846)4.01779594
14endocardial cushion development (GO:0003197)4.00257785
15negative regulation of fatty acid transport (GO:2000192)3.96263112
16basement membrane organization (GO:0071711)3.85845381
17skin morphogenesis (GO:0043589)3.85068426
18extracellular fibril organization (GO:0043206)3.79982042
19hippo signaling (GO:0035329)3.79346476
20wound healing, spreading of epidermal cells (GO:0035313)3.76068137
21mesenchymal-epithelial cell signaling (GO:0060638)3.62437598
22regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.53717811
23retina vasculature morphogenesis in camera-type eye (GO:0061299)3.51230789
24cell migration involved in sprouting angiogenesis (GO:0002042)3.44320857
25omega-hydroxylase P450 pathway (GO:0097267)3.44226535
26regulation of plasminogen activation (GO:0010755)3.43766281
27type B pancreatic cell proliferation (GO:0044342)3.40317065
28metanephric mesenchyme development (GO:0072075)3.39907879
29regulation of fibrinolysis (GO:0051917)3.39503004
30hemidesmosome assembly (GO:0031581)3.35698409
31regulation of integrin-mediated signaling pathway (GO:2001044)3.34685060
32craniofacial suture morphogenesis (GO:0097094)3.32960610
33negative regulation of chondrocyte differentiation (GO:0032331)3.31782300
34kidney mesenchyme development (GO:0072074)3.29947100
35epithelial cell-cell adhesion (GO:0090136)3.29200085
36negative regulation of axon extension involved in axon guidance (GO:0048843)3.28434673
37mesodermal cell differentiation (GO:0048333)3.28125607
38smooth muscle tissue development (GO:0048745)3.27146140
39collagen metabolic process (GO:0032963)3.24430185
40paraxial mesoderm development (GO:0048339)3.23303992
41wound healing, spreading of cells (GO:0044319)3.21887921
42actin filament depolymerization (GO:0030042)3.21654768
43glomerular basement membrane development (GO:0032836)3.21654381
44fibril organization (GO:0097435)3.17728159
45apoptotic cell clearance (GO:0043277)3.16378298
46G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.15512071
47protein localization to cell surface (GO:0034394)3.15235189
48vascular endothelial growth factor signaling pathway (GO:0038084)3.14496028
49renal filtration (GO:0097205)3.12802324
50cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.12772828
51collagen catabolic process (GO:0030574)3.11030015
52dermatan sulfate metabolic process (GO:0030205)3.09321905
53cellular response to vitamin (GO:0071295)3.05666292
54multicellular organismal macromolecule metabolic process (GO:0044259)3.03218884
55regulation of tight junction assembly (GO:2000810)3.02481777
56substrate adhesion-dependent cell spreading (GO:0034446)3.01701100
57cell migration involved in heart development (GO:0060973)2.99844298
58cellular response to vitamin D (GO:0071305)2.99781005
59plasma membrane repair (GO:0001778)2.99468983
60planar cell polarity pathway involved in neural tube closure (GO:0090179)2.98594796
61endothelial cell morphogenesis (GO:0001886)2.98170801
62fibroblast migration (GO:0010761)2.96732145
63extracellular matrix disassembly (GO:0022617)2.95661370
64anterior/posterior axis specification, embryo (GO:0008595)2.94384516
65blood vessel endothelial cell migration (GO:0043534)2.93836307
66positive regulation of epithelial to mesenchymal transition (GO:0010718)2.93331111
67positive regulation of extracellular matrix organization (GO:1903055)2.93080520
68insulin-like growth factor receptor signaling pathway (GO:0048009)2.89041098
69regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.88899440
70multicellular organismal metabolic process (GO:0044236)2.88686355
71regulation of axon extension involved in axon guidance (GO:0048841)2.87608490
72notochord development (GO:0030903)2.87397426
73peptidyl-proline hydroxylation (GO:0019511)2.87212743
74polarized epithelial cell differentiation (GO:0030859)2.87017757
75multicellular organismal catabolic process (GO:0044243)2.85238331
76muscle cell migration (GO:0014812)2.85174770
77cranial suture morphogenesis (GO:0060363)2.84342345
78positive regulation of fibroblast migration (GO:0010763)2.84131016
79heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.82042620
80positive regulation of macrophage activation (GO:0043032)2.81770822
81glomerular filtration (GO:0003094)2.81146450
82negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.80174312
83regulation of transforming growth factor beta2 production (GO:0032909)2.77066362
84extracellular matrix assembly (GO:0085029)2.76841889
85neural crest cell development (GO:0014032)2.76329344
86cell-substrate adherens junction assembly (GO:0007045)2.76108729
87focal adhesion assembly (GO:0048041)2.76108729
88lymphangiogenesis (GO:0001946)2.75043134
89positive regulation of blood vessel endothelial cell migration (GO:0043536)2.73028460
90adherens junction assembly (GO:0034333)2.72612955
91pericardium development (GO:0060039)2.71662536
92negative regulation of embryonic development (GO:0045992)2.71600942
93negative regulation of catenin import into nucleus (GO:0035414)2.71396493
94dermatan sulfate biosynthetic process (GO:0030208)2.70721338
95negative regulation of BMP signaling pathway (GO:0030514)2.70626409
96chondrocyte development (GO:0002063)2.69963004
97midgut development (GO:0007494)2.68835492
98protein retention in ER lumen (GO:0006621)2.68534030
99peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.68162714
100negative regulation of axon guidance (GO:1902668)2.67780029
101cell-substrate adhesion (GO:0031589)2.66209505
102negative regulation of cartilage development (GO:0061037)2.66198679
103cochlea morphogenesis (GO:0090103)2.65694399
104regulation of SMAD protein import into nucleus (GO:0060390)2.63732339
105regulation of chondrocyte differentiation (GO:0032330)2.63349043
106regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.62993274
107stress fiber assembly (GO:0043149)2.62931624
108cell-substrate junction assembly (GO:0007044)2.62199340
109hypotonic response (GO:0006971)2.61980554
110face morphogenesis (GO:0060325)2.61723571
111sprouting angiogenesis (GO:0002040)2.61101647
112artery development (GO:0060840)2.60391270
113negative regulation of smooth muscle cell migration (GO:0014912)2.59733624
114regulation of hippo signaling (GO:0035330)2.59145157
115extracellular matrix organization (GO:0030198)2.56986903
116fibrinolysis (GO:0042730)2.56952764
117wound healing (GO:0042060)2.56103888
118extracellular structure organization (GO:0043062)2.55832598
119positive regulation of fatty acid beta-oxidation (GO:0032000)2.55423839
120positive regulation of osteoblast proliferation (GO:0033690)2.55156311
121negative chemotaxis (GO:0050919)2.55054037
122substrate-dependent cell migration (GO:0006929)2.54329724
123positive regulation of cartilage development (GO:0061036)2.53630597
124atrioventricular valve morphogenesis (GO:0003181)2.53512795
125regulation of cartilage development (GO:0061035)2.52599632
126positive regulation of collagen biosynthetic process (GO:0032967)2.51092417
127protein hydroxylation (GO:0018126)2.50337079
128mesenchyme development (GO:0060485)2.49034172
129positive regulation of mesenchymal cell proliferation (GO:0002053)2.48213252
130regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.47634234
131regulation of gastrulation (GO:0010470)2.47437243
132embryonic cranial skeleton morphogenesis (GO:0048701)2.47348930
133platelet degranulation (GO:0002576)2.45696522

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.35352566
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.24464154
3RARG_19884340_ChIP-ChIP_MEFs_Mouse4.58838725
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.37703759
5* CLOCK_20551151_ChIP-Seq_293T_Human3.21115872
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.10062445
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.89826170
8* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.70430891
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.67980373
10WT1_19549856_ChIP-ChIP_CCG9911_Human2.60473445
11* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.42213000
12CJUN_26792858_Chip-Seq_BT549_Human2.39882284
13* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.38450935
14* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.34411618
15HIF1A_21447827_ChIP-Seq_MCF-7_Human2.28394350
16* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.27844615
17RXR_22158963_ChIP-Seq_LIVER_Mouse2.18892525
18* BRD4_25478319_ChIP-Seq_HGPS_Human2.17258473
19SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.12254886
20NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.09356146
21NRF2_20460467_ChIP-Seq_MEFs_Mouse2.09356146
22RBPJ_22232070_ChIP-Seq_NCS_Mouse2.06565516
23PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.02161700
24WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.01887628
25NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.01414228
26ESR1_15608294_ChIP-ChIP_MCF-7_Human1.98720265
27EP300_21415370_ChIP-Seq_HL-1_Mouse1.95529845
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.95112361
29PPAR_26484153_Chip-Seq_NCI-H1993_Human1.92472668
30LXR_22158963_ChIP-Seq_LIVER_Mouse1.92406577
31PPARA_22158963_ChIP-Seq_LIVER_Mouse1.82852726
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.78005504
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.77199814
34TP53_20018659_ChIP-ChIP_R1E_Mouse1.76111943
35* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.74497164
36* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.74497164
37EGR1_19374776_ChIP-ChIP_THP-1_Human1.72299829
38ESR2_21235772_ChIP-Seq_MCF-7_Human1.71806513
39* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.66728685
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.61711540
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.61131900
42SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.58833230
43TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.58560355
44CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.56800691
45FOXO3_23340844_ChIP-Seq_DLD1_Human1.55879038
46* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.54759251
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.49767793
48SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.46493935
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.44232529
50EZH2_18974828_ChIP-Seq_MESCs_Mouse1.43893882
51RNF2_18974828_ChIP-Seq_MESCs_Mouse1.43893882
52SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.43088249
53P300_27058665_Chip-Seq_ZR-75-30cells_Human1.42088155
54* SOX2_20726797_ChIP-Seq_SW620_Human1.39341389
55ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38682552
56SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.38546220
57ZNF217_24962896_ChIP-Seq_MCF-7_Human1.38439116
58CDX2_19796622_ChIP-Seq_MESCs_Mouse1.38415225
59JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36284941
60* TP53_18474530_ChIP-ChIP_U2OS_Human1.34438250
61PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.33579814
62UBF1/2_26484160_Chip-Seq_HMECs_Human1.33529438
63HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.32282131
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32104230
65TCF3_18692474_ChIP-Seq_MEFs_Mouse1.31840067
66SMC1_22415368_ChIP-Seq_MEFs_Mouse1.30237471
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.27899275
68KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27682391
69KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27682391
70KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27682391
71SOX9_24532713_ChIP-Seq_HFSC_Mouse1.25990593
72JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25624823
73ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.25111680
74ATF3_27146783_Chip-Seq_COLON_Human1.25020427
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.20635067
76TP53_22127205_ChIP-Seq_IMR90_Human1.19596705
77SA1_22415368_ChIP-Seq_MEFs_Mouse1.19179152
78* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.19157560
79* TP53_16413492_ChIP-PET_HCT116_Human1.19137076
80PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.17962975
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.17527578
82TBX3_20139965_ChIP-Seq_ESCs_Mouse1.17097702
83TBX3_20139965_ChIP-Seq_MESCs_Mouse1.16470413
84SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.13713042
85TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13405985
86ESR1_20079471_ChIP-ChIP_T-47D_Human1.13165430
87AHR_22903824_ChIP-Seq_MCF-7_Human1.13107387
88SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.12877139
89SALL1_21062744_ChIP-ChIP_HESCs_Human1.12830756
90* TP53_23651856_ChIP-Seq_MEFs_Mouse1.12359509
91ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11567762
92* ISL1_27105846_Chip-Seq_CPCs_Mouse1.10305457
93GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.09877023
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08901520
95SMAD_19615063_ChIP-ChIP_OVARY_Human1.08429921
96ZFP281_18757296_ChIP-ChIP_E14_Mouse1.07587518
97TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.07470952
98* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.06845944
99TBX20_22328084_ChIP-Seq_HEART_Mouse1.06377840
100TBX20_22080862_ChIP-Seq_HEART_Mouse1.06377840
101ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05354003
102POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05074491
103ARNT_22903824_ChIP-Seq_MCF-7_Human1.04441470
104CDX2_20551321_ChIP-Seq_CACO-2_Human1.04415037
105GBX2_23144817_ChIP-Seq_PC3_Human1.04349188
106GATA2_21666600_ChIP-Seq_HMVEC_Human1.02776724
107NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.02611538
108MTF2_20144788_ChIP-Seq_MESCs_Mouse1.02059240
109SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.02041100
110RACK7_27058665_Chip-Seq_MCF-7_Human1.01964440
111EED_16625203_ChIP-ChIP_MESCs_Mouse1.01251450
112* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.01035930
113* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.00714170
114STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.00602987
115AR_21909140_ChIP-Seq_LNCAP_Human1.00451801
116ZFP281_27345836_Chip-Seq_ESCs_Mouse0.97253064
117SMC3_22415368_ChIP-Seq_MEFs_Mouse0.96112410
118YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94092885
119* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94082696
120DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93935875
121ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93856207
122OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93650794
123PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.93311356
124ZFP57_27257070_Chip-Seq_ESCs_Mouse0.93270946
125NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92974900
126KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92853580
127TCF4_18268006_ChIP-ChIP_LS174T_Human0.92826079
128SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92387812
129NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91278917
130SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90756343
131* TP63_23658742_ChIP-Seq_EP156T_Human0.89868330

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.50289826
2MP0003705_abnormal_hypodermis_morpholog4.35667163
3MP0005503_abnormal_tendon_morphology4.20046169
4MP0005275_abnormal_skin_tensile4.15050266
5MP0003279_aneurysm3.40687975
6MP0004272_abnormal_basement_membrane3.09596424
7MP0005623_abnormal_meninges_morphology3.09559028
8MP0009384_cardiac_valve_regurgitation2.93469483
9MP0010352_gastrointestinal_tract_polyps2.41373737
10MP0010030_abnormal_orbit_morphology2.36979434
11MP0001958_emphysema2.27120029
12MP0003566_abnormal_cell_adhesion2.24414133
13MP0009053_abnormal_anal_canal2.24168869
14MP0005257_abnormal_intraocular_pressure2.06822772
15MP0010368_abnormal_lymphatic_system2.06101757
16MP0005023_abnormal_wound_healing2.04694918
17MP0005508_abnormal_skeleton_morphology1.94366800
18MP0006054_spinal_hemorrhage1.88853569
19MP0003091_abnormal_cell_migration1.85175572
20MP0002295_abnormal_pulmonary_circulatio1.74097943
21MP0009250_abnormal_appendicular_skeleto1.72704734
22MP0002060_abnormal_skin_morphology1.68267221
23* MP0003385_abnormal_body_wall1.62616922
24MP0009780_abnormal_chondrocyte_physiolo1.59748083
25MP0000767_abnormal_smooth_muscle1.54689789
26MP0000751_myopathy1.51730358
27MP0003942_abnormal_urinary_system1.47901607
28MP0000733_abnormal_muscle_development1.46319420
29MP0001299_abnormal_eye_distance/1.38410856
30MP0001243_abnormal_dermal_layer1.37343349
31MP0002282_abnormal_trachea_morphology1.36090369
32MP0000534_abnormal_ureter_morphology1.35837313
33MP0002896_abnormal_bone_mineralization1.34846866
34MP0002108_abnormal_muscle_morphology1.34449977
35MP0003252_abnormal_bile_duct1.33567082
36MP0002932_abnormal_joint_morphology1.30735938
37MP0003941_abnormal_skin_development1.25146616
38MP0001542_abnormal_bone_strength1.23896047
39MP0003755_abnormal_palate_morphology1.23462660
40MP0000428_abnormal_craniofacial_morphol1.22285373
41MP0002877_abnormal_melanocyte_morpholog1.20890741
42MP0000537_abnormal_urethra_morphology1.20594775
43MP0000163_abnormal_cartilage_morphology1.20351011
44MP0001879_abnormal_lymphatic_vessel1.19850071
45MP0005171_absent_coat_pigmentation1.19568591
46MP0010386_abnormal_urinary_bladder1.18310662
47MP0003115_abnormal_respiratory_system1.16617181
48MP0000516_abnormal_urinary_system1.13616654
49MP0005367_renal/urinary_system_phenotyp1.13616654
50MP0003937_abnormal_limbs/digits/tail_de1.12044307
51MP0002168_other_aberrant_phenotype1.10955022
52MP0003283_abnormal_digestive_organ1.09535178
53MP0000013_abnormal_adipose_tissue1.08412774
54MP0001348_abnormal_lacrimal_gland1.05641039
55MP0004858_abnormal_nervous_system1.05539828
56MP0002115_abnormal_skeleton_extremities1.04630899
57MP0003935_abnormal_craniofacial_develop1.02966733
58MP0005360_urolithiasis1.02410853
59MP0003045_fibrosis1.00084929
60MP0002128_abnormal_blood_circulation0.99731281
61MP0000432_abnormal_head_morphology0.98403012
62MP0000462_abnormal_digestive_system0.98253077
63MP0000762_abnormal_tongue_morphology0.96533586
64MP0000749_muscle_degeneration0.95626359
65MP0002233_abnormal_nose_morphology0.94576605
66MP0001614_abnormal_blood_vessel0.93807429
67MP0005390_skeleton_phenotype0.93386179
68MP0005197_abnormal_uvea_morphology0.92511239
69MP0000750_abnormal_muscle_regeneration0.92254301
70MP0005248_abnormal_Harderian_gland0.92141503
71MP0002113_abnormal_skeleton_development0.91540211
72MP0002249_abnormal_larynx_morphology0.91092006
73MP0002697_abnormal_eye_size0.91013281
74MP0000049_abnormal_middle_ear0.90157078
75MP0000538_abnormal_urinary_bladder0.90141552
76MP0002139_abnormal_hepatobiliary_system0.89377128
77MP0006138_congestive_heart_failure0.89114719
78MP0002925_abnormal_cardiovascular_devel0.87372750
79MP0005076_abnormal_cell_differentiation0.84875213
80MP0001915_intracranial_hemorrhage0.83685873
81MP0000003_abnormal_adipose_tissue0.82121265
82MP0005193_abnormal_anterior_eye0.82069646
83MP0002111_abnormal_tail_morphology0.81467189
84MP0002116_abnormal_craniofacial_bone0.79709255
85MP0005620_abnormal_muscle_contractility0.79549634
86MP0005084_abnormal_gallbladder_morpholo0.79359413
87MP0002092_abnormal_eye_morphology0.78933705
88MP0002109_abnormal_limb_morphology0.78650329
89MP0005164_abnormal_response_to0.76861798
90MP0003300_gastrointestinal_ulcer0.75683498
91MP0005595_abnormal_vascular_smooth0.75350507
92MP0002133_abnormal_respiratory_system0.75349962
93MP0005388_respiratory_system_phenotype0.75349962
94MP0003950_abnormal_plasma_membrane0.74184749
95MP0004036_abnormal_muscle_relaxation0.72726150
96MP0000759_abnormal_skeletal_muscle0.71958526
97MP0002254_reproductive_system_inflammat0.71927869
98MP0004197_abnormal_fetal_growth/weight/0.71523533
99MP0004134_abnormal_chest_morphology0.70104732
100MP0003448_altered_tumor_morphology0.69749714
101MP0005409_darkened_coat_color0.69489008
102MP0004883_abnormal_blood_vessel0.67513049
103MP0005085_abnormal_gallbladder_physiolo0.66844075
104MP0000467_abnormal_esophagus_morphology0.66497900
105MP0001175_abnormal_lung_morphology0.65343355
106MP0010630_abnormal_cardiac_muscle0.65118782
107MP0003868_abnormal_feces_composition0.64634310
108MP0004084_abnormal_cardiac_muscle0.63829718
109MP0002114_abnormal_axial_skeleton0.63561107
110MP0002928_abnormal_bile_duct0.63130000
111MP0001849_ear_inflammation0.62770961
112MP0005365_abnormal_bile_salt0.61843509
113MP0005220_abnormal_exocrine_pancreas0.60849352
114MP0004087_abnormal_muscle_fiber0.60184462
115MP0002177_abnormal_outer_ear0.59705468
116MP0000266_abnormal_heart_morphology0.58423519
117MP0005187_abnormal_penis_morphology0.58280005
118MP0002089_abnormal_postnatal_growth/wei0.57423754
119MP0002933_joint_inflammation0.52193557
120MP0003828_pulmonary_edema0.51958243
121MP0001270_distended_abdomen0.51049518
122MP0005165_increased_susceptibility_to0.50594468

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.54876653
2Premature rupture of membranes (HP:0001788)7.30612615
3Aortic dissection (HP:0002647)4.93200188
4Peritonitis (HP:0002586)4.65570205
5Aortic aneurysm (HP:0004942)4.63889124
6Shallow orbits (HP:0000586)4.58699196
7Atrophic scars (HP:0001075)4.16199141
8Ankle contracture (HP:0006466)4.05249359
9Soft skin (HP:0000977)3.93286238
10Cerebral aneurysm (HP:0004944)3.83053790
11Abnormality of dentin (HP:0010299)3.72152551
12Broad metatarsal (HP:0001783)3.62718564
13Dilatation of the ascending aorta (HP:0005111)3.61944748
14Bladder diverticulum (HP:0000015)3.55440067
15Cervical subluxation (HP:0003308)3.54291351
16Mitral valve prolapse (HP:0001634)3.29700226
17Fragile skin (HP:0001030)3.28285114
18Blue sclerae (HP:0000592)3.21684532
19Wormian bones (HP:0002645)3.18952986
20Neonatal short-limb short stature (HP:0008921)3.08164081
21Genu recurvatum (HP:0002816)3.06726686
22Biconcave vertebral bodies (HP:0004586)3.04307756
23Aortic regurgitation (HP:0001659)3.02332638
24Spinal rigidity (HP:0003306)2.94506225
25Vascular tortuosity (HP:0004948)2.90538036
26Wrist flexion contracture (HP:0001239)2.85096018
27Increased connective tissue (HP:0009025)2.82537605
28Aneurysm (HP:0002617)2.81779390
29Vertebral compression fractures (HP:0002953)2.81031132
30Abnormal delivery (HP:0001787)2.70099975
31Infantile muscular hypotonia (HP:0008947)2.68084378
32Follicular hyperkeratosis (HP:0007502)2.66046204
33Mesomelia (HP:0003027)2.56087703
34Bowel diverticulosis (HP:0005222)2.55416785
35Wide anterior fontanel (HP:0000260)2.51664823
36Camptodactyly of toe (HP:0001836)2.49774992
37Hyperextensible skin (HP:0000974)2.48055139
38Overgrowth (HP:0001548)2.48038634
39Type 1 muscle fiber predominance (HP:0003803)2.47071338
40Short nail (HP:0001799)2.46923054
41Coronal craniosynostosis (HP:0004440)2.45565970
42Deep venous thrombosis (HP:0002625)2.37244096
43Slender build (HP:0001533)2.36462076
44Buphthalmos (HP:0000557)2.35528279
45Mitral stenosis (HP:0001718)2.34221979
46Aortic valve stenosis (HP:0001650)2.33545837
47Ectopia lentis (HP:0001083)2.30437241
48Arterial tortuosity (HP:0005116)2.30083639
49Elbow flexion contracture (HP:0002987)2.29553893
50Abnormality of the acetabulum (HP:0003170)2.29496271
51Deviation of the hallux (HP:0010051)2.28138336
52Osteolytic defects of the hand bones (HP:0009699)2.27774479
53Osteolytic defects of the phalanges of the hand (HP:0009771)2.27774479
54Hypoplasia of the iris (HP:0007676)2.26985190
55Spinal cord lesions (HP:0100561)2.19505281
56Syringomyelia (HP:0003396)2.19505281
57Right ventricular cardiomyopathy (HP:0011663)2.18000448
58Hallux valgus (HP:0001822)2.17552918
59Knee flexion contracture (HP:0006380)2.15251283
60Cardiovascular calcification (HP:0011915)2.13634821
61Renal duplication (HP:0000075)2.12261289
62Abnormality of the peritoneum (HP:0002585)2.11250038
63Tibial bowing (HP:0002982)2.10313629
64Absent frontal sinuses (HP:0002688)2.09241161
65Ulnar bowing (HP:0003031)2.07903132
66Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.07536730
67Short 4th metacarpal (HP:0010044)2.07536730
68Increased density of long bones (HP:0006392)2.07377706
69Mild short stature (HP:0003502)2.04560717
70Bell-shaped thorax (HP:0001591)1.99100263
71Osteoarthritis (HP:0002758)1.96871784
72Tarsal synostosis (HP:0008368)1.96855949
73Hypoventilation (HP:0002791)1.96839634
74Thin bony cortex (HP:0002753)1.96650591
75Scapular winging (HP:0003691)1.96443971
76Round ear (HP:0100830)1.96356351
77Mitral regurgitation (HP:0001653)1.95818681
78Joint laxity (HP:0001388)1.94799951
79Limited hip movement (HP:0008800)1.94426073
80Disproportionate tall stature (HP:0001519)1.94355667
81Mildly elevated creatine phosphokinase (HP:0008180)1.92155439
82Radial bowing (HP:0002986)1.91469236
83Inguinal hernia (HP:0000023)1.90367185
84Venous abnormality (HP:0002624)1.90094888
85Pulmonary artery stenosis (HP:0004415)1.89954878
86Back pain (HP:0003418)1.89918539
87Joint stiffness (HP:0001387)1.89517041
88Increased variability in muscle fiber diameter (HP:0003557)1.89072534
89Asymmetry of the thorax (HP:0001555)1.88202397
90Abnormality of the 4th metacarpal (HP:0010012)1.87275225
91Venous insufficiency (HP:0005293)1.87151373
92Fused cervical vertebrae (HP:0002949)1.86187771
93Congenital glaucoma (HP:0001087)1.84480548
94Short hallux (HP:0010109)1.84444393
95Upper limb amyotrophy (HP:0009129)1.84421721
96Distal upper limb amyotrophy (HP:0007149)1.84421721
97Cupped ribs (HP:0000887)1.84095079
98Broad long bones (HP:0005622)1.84028582
99Joint contractures involving the joints of the feet (HP:0100492)1.83279855
100Flexion contracture of toe (HP:0005830)1.83279855
101Abnormal cartilage morphology (HP:0002763)1.82965496
102Spondylolisthesis (HP:0003302)1.82780377
103Natal tooth (HP:0000695)1.82338599
104Flared iliac wings (HP:0002869)1.81795381
105Vertebral arch anomaly (HP:0008438)1.80872659
106Abnormality of the anterior chamber (HP:0000593)1.80500336
107Bowed forearm bones (HP:0003956)1.80277363
108Bowing of the arm (HP:0006488)1.80277363
109Breech presentation (HP:0001623)1.79427411
110Abnormality of the calcaneus (HP:0008364)1.79290109
111Increased mean platelet volume (HP:0011877)1.79154786
112Abnormality of skeletal muscle fiber size (HP:0012084)1.78639087
113Hepatoblastoma (HP:0002884)1.78197581
114Nonimmune hydrops fetalis (HP:0001790)1.77995602
115Lymphangioma (HP:0100764)1.77494846
116Delayed gross motor development (HP:0002194)1.75244396
117Ovoid vertebral bodies (HP:0003300)1.75223046
118Femoral bowing (HP:0002980)1.75005422
119Delayed cranial suture closure (HP:0000270)1.74894291
120Abnormality of carpal bone ossification (HP:0006257)1.73489127
121Synostosis involving bones of the feet (HP:0009140)1.72736652
122Synostosis involving bones of the lower limbs (HP:0009138)1.72736652
123Chondrocalcinosis (HP:0000934)1.72086336
124Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.71374186
125Protruding ear (HP:0000411)1.69883912
126Broad ribs (HP:0000885)1.69116976
127Flat cornea (HP:0007720)1.68595987
128Aplasia/Hypoplasia of the hallux (HP:0008362)1.68446647
129Delayed closure of the anterior fontanelle (HP:0001476)1.68181005
130Abnormal ossification of hand bones (HP:0005921)1.66111703
131Morphological abnormality of the middle ear (HP:0008609)1.65977870
132Persistence of primary teeth (HP:0006335)1.65863137
133Redundant skin (HP:0001582)1.63318503

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.01577395
2LATS13.95350957
3TTN3.92288621
4PDGFRA3.37393566
5TRIB33.10502351
6LATS23.00637626
7ERN12.91147337
8EPHB22.59137208
9SIK12.53418098
10PTK22.11280987
11EPHA22.05013002
12MYLK1.96863027
13PKN21.94849152
14FRK1.93943829
15FER1.72660279
16RIPK11.71521947
17CDK121.68012118
18PIK3CA1.61983029
19TRPM71.60744198
20DMPK1.57942220
21* PAK21.57823544
22TESK11.56573664
23BMX1.52840775
24PTK61.52569950
25STK38L1.51288446
26STK31.50852172
27EPHA31.50574619
28LIMK11.48530553
29TGFBR21.46052226
30MET1.43082905
31STK381.41373800
32PIK3CG1.35807074
33LRRK21.35559047
34PAK41.34607125
35PTK2B1.25981924
36FGFR11.24271303
37MOS1.23257379
38MTOR1.23056948
39NEK91.21090528
40ROCK11.18088766
41PDGFRB1.10236726
42NUAK11.08980064
43STK101.08967761
44ERBB31.08727758
45RPS6KA41.05455471
46PRKD31.02504212
47ZAK1.00318003
48ERBB40.98708815
49FGFR20.96561295
50STK240.93873674
51CDK60.91945364
52PNCK0.88254811
53PIM20.85779896
54CAMK1D0.84300795
55MAP3K100.83457969
56ILK0.82402972
57MAP2K10.81700540
58PRKG20.78955734
59TIE10.77452100
60FGFR40.71754393
61MAP3K120.70773352
62ABL20.70209408
63KIT0.69645045
64MUSK0.68474218
65TGFBR10.66315518
66DYRK1B0.66015808
67CDC42BPA0.65218760
68RPS6KA20.64349354
69PRKCE0.63740754
70ROCK20.63514028
71NTRK10.63039088
72CAMK1G0.62973848
73MELK0.62811052
74MAP3K60.62395015
75* INSR0.62185791
76LMTK20.62121677
77ERBB20.61157562
78KDR0.60922534
79EEF2K0.59215828
80DAPK30.58176653
81PAK10.56666428
82PRKD10.53255077
83PLK20.51974382
84EPHB10.51377861
85MAP3K30.51104892
86CAMK2G0.50143690
87PAK60.49464805
88ADRBK10.49039386
89STK390.47938042
90WNK10.47826931
91MAP3K80.46618820
92PRKD20.44474087
93IGF1R0.44368458
94TYRO30.44335400
95GSK3A0.44267144
96SRC0.43362651
97FGFR30.43289410
98BRSK20.42152243
99TESK20.41829159
100RPS6KB20.40337104
101MST1R0.40302224
102RET0.40170360
103GRK70.39108156
104BCR0.38902476
105FLT30.37029783
106CAMK2D0.35291605
107ICK0.35149241
108ABL10.33960743
109MAPKAPK20.31664651
110TAOK20.31179511
111CLK10.30857573
112MAPK70.30577397
113CDK70.30536508
114PRKCH0.29108369
115MAPKAPK30.28748485
116EGFR0.27413694
117CAMK2B0.27390598
118PRKG10.26665716
119NLK0.26446982
120WNK40.25952429
121SCYL20.25749541
122* MAPK10.25243167
123CDK80.24928694
124MAP2K30.24783784
125TTK0.24584872
126JAK10.24307588
127AKT30.23592090
128AKT20.23222372
129MARK10.17718845

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.74622843
2Focal adhesion_Homo sapiens_hsa045102.89300449
3Adherens junction_Homo sapiens_hsa045202.40080386
4Proteoglycans in cancer_Homo sapiens_hsa052052.30964372
5Bladder cancer_Homo sapiens_hsa052192.25829525
6Complement and coagulation cascades_Homo sapiens_hsa046102.17618004
7Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.08691617
8TGF-beta signaling pathway_Homo sapiens_hsa043502.01454364
9Hippo signaling pathway_Homo sapiens_hsa043902.00938037
10Primary bile acid biosynthesis_Homo sapiens_hsa001201.95874319
11Small cell lung cancer_Homo sapiens_hsa052221.92417224
12Nitrogen metabolism_Homo sapiens_hsa009101.91780252
13Amoebiasis_Homo sapiens_hsa051461.90848351
14Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.84762094
15Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.84704098
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.83983216
17MicroRNAs in cancer_Homo sapiens_hsa052061.78229314
18Basal cell carcinoma_Homo sapiens_hsa052171.72177898
19Dilated cardiomyopathy_Homo sapiens_hsa054141.70706099
20Protein digestion and absorption_Homo sapiens_hsa049741.64025083
21Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.57397865
22AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.56223960
23Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.52445353
24Tryptophan metabolism_Homo sapiens_hsa003801.44562447
25Chemical carcinogenesis_Homo sapiens_hsa052041.44322725
26PI3K-Akt signaling pathway_Homo sapiens_hsa041511.40095353
27p53 signaling pathway_Homo sapiens_hsa041151.38266203
28Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.37707357
29Hedgehog signaling pathway_Homo sapiens_hsa043401.36260188
30Regulation of actin cytoskeleton_Homo sapiens_hsa048101.34231405
31Malaria_Homo sapiens_hsa051441.28129388
32* Vascular smooth muscle contraction_Homo sapiens_hsa042701.27287444
33Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.26968972
34Melanoma_Homo sapiens_hsa052181.26320974
35Arginine biosynthesis_Homo sapiens_hsa002201.26048334
36Tight junction_Homo sapiens_hsa045301.24607426
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.21434102
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.19441293
39Pentose and glucuronate interconversions_Homo sapiens_hsa000401.19022541
40PPAR signaling pathway_Homo sapiens_hsa033201.18676451
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.15895706
42Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.14622301
43Glycosaminoglycan degradation_Homo sapiens_hsa005311.14567248
44Chronic myeloid leukemia_Homo sapiens_hsa052201.11600530
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05863146
46Prostate cancer_Homo sapiens_hsa052151.04775904
47Fatty acid degradation_Homo sapiens_hsa000710.99478443
48Pathways in cancer_Homo sapiens_hsa052000.97556849
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.96818736
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95932206
51Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.95804977
52Rap1 signaling pathway_Homo sapiens_hsa040150.92002655
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84899409
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84339962
55Axon guidance_Homo sapiens_hsa043600.83829543
56Pancreatic cancer_Homo sapiens_hsa052120.82583026
57Viral myocarditis_Homo sapiens_hsa054160.82177255
58Bile secretion_Homo sapiens_hsa049760.81077461
59Caffeine metabolism_Homo sapiens_hsa002320.80903165
60Lysine degradation_Homo sapiens_hsa003100.80476203
61Wnt signaling pathway_Homo sapiens_hsa043100.80055770
62Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.78932696
63Shigellosis_Homo sapiens_hsa051310.77403560
64Selenocompound metabolism_Homo sapiens_hsa004500.74236070
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70576977
66Glioma_Homo sapiens_hsa052140.70512088
67Platelet activation_Homo sapiens_hsa046110.69852344
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.69451865
69Thyroid hormone synthesis_Homo sapiens_hsa049180.69028350
70Ovarian steroidogenesis_Homo sapiens_hsa049130.68924442
71Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68841046
72Retinol metabolism_Homo sapiens_hsa008300.68098261
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.67732209
74Fatty acid metabolism_Homo sapiens_hsa012120.67024478
75Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63524800
76Starch and sucrose metabolism_Homo sapiens_hsa005000.62692462
77Renin secretion_Homo sapiens_hsa049240.60559313
78HTLV-I infection_Homo sapiens_hsa051660.58784563
79Vibrio cholerae infection_Homo sapiens_hsa051100.58440820
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57695594
81One carbon pool by folate_Homo sapiens_hsa006700.57160561
82Arginine and proline metabolism_Homo sapiens_hsa003300.55988265
83Thyroid cancer_Homo sapiens_hsa052160.55845283
84Ras signaling pathway_Homo sapiens_hsa040140.55738254
85Tyrosine metabolism_Homo sapiens_hsa003500.54294461
86Renal cell carcinoma_Homo sapiens_hsa052110.53272566
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53105140
88Dorso-ventral axis formation_Homo sapiens_hsa043200.51259757
89Phenylalanine metabolism_Homo sapiens_hsa003600.49173228
90Endocytosis_Homo sapiens_hsa041440.48412294
91TNF signaling pathway_Homo sapiens_hsa046680.48265137
92Cocaine addiction_Homo sapiens_hsa050300.47901398
93Melanogenesis_Homo sapiens_hsa049160.47049461
94Estrogen signaling pathway_Homo sapiens_hsa049150.46791367
95Endometrial cancer_Homo sapiens_hsa052130.46105365
96Notch signaling pathway_Homo sapiens_hsa043300.45731075
97Prion diseases_Homo sapiens_hsa050200.44517035
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44466804
99Sulfur metabolism_Homo sapiens_hsa009200.43686469
100Oxytocin signaling pathway_Homo sapiens_hsa049210.43367953
101cAMP signaling pathway_Homo sapiens_hsa040240.43077083
102Vitamin B6 metabolism_Homo sapiens_hsa007500.42769536
103Glutathione metabolism_Homo sapiens_hsa004800.42766279
104Insulin resistance_Homo sapiens_hsa049310.42039422
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41199335
106Toxoplasmosis_Homo sapiens_hsa051450.41060501
107AMPK signaling pathway_Homo sapiens_hsa041520.39772661
108Sphingolipid metabolism_Homo sapiens_hsa006000.38303022
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37983635
110N-Glycan biosynthesis_Homo sapiens_hsa005100.37515207
111Colorectal cancer_Homo sapiens_hsa052100.37301546
112MAPK signaling pathway_Homo sapiens_hsa040100.37195313
1132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36761846
114Glucagon signaling pathway_Homo sapiens_hsa049220.35889739
115Aldosterone synthesis and secretion_Homo sapiens_hsa049250.35740583
116HIF-1 signaling pathway_Homo sapiens_hsa040660.35654915
117mTOR signaling pathway_Homo sapiens_hsa041500.35182385
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.35133558
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33647093
120Gap junction_Homo sapiens_hsa045400.33542657
121Renin-angiotensin system_Homo sapiens_hsa046140.32909328
122Histidine metabolism_Homo sapiens_hsa003400.32769428
123Viral carcinogenesis_Homo sapiens_hsa052030.32316549
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32277353
125FoxO signaling pathway_Homo sapiens_hsa040680.31696762
126Gastric acid secretion_Homo sapiens_hsa049710.31252996
127Protein export_Homo sapiens_hsa030600.30349948
128GnRH signaling pathway_Homo sapiens_hsa049120.30056001
129Circadian rhythm_Homo sapiens_hsa047100.29546812
130Calcium signaling pathway_Homo sapiens_hsa040200.29052457
131Longevity regulating pathway - mammal_Homo sapiens_hsa042110.27834486
132Neurotrophin signaling pathway_Homo sapiens_hsa047220.26053845
133Galactose metabolism_Homo sapiens_hsa000520.25404439
134Other glycan degradation_Homo sapiens_hsa005110.24940054

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