CACNG8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.20350907
2locomotory exploration behavior (GO:0035641)6.17958030
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.17393643
4vocalization behavior (GO:0071625)6.04258597
5* regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.70911875
6synaptic vesicle maturation (GO:0016188)5.59949857
7ionotropic glutamate receptor signaling pathway (GO:0035235)5.56588992
8* regulation of glutamate receptor signaling pathway (GO:1900449)5.38830128
9protein localization to synapse (GO:0035418)5.23604751
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.20785377
11synaptic vesicle exocytosis (GO:0016079)5.11809426
12exploration behavior (GO:0035640)5.08787883
13regulation of neuronal synaptic plasticity (GO:0048168)5.03558091
14regulation of long-term neuronal synaptic plasticity (GO:0048169)5.01375489
15behavioral response to nicotine (GO:0035095)4.92988336
16glutamate secretion (GO:0014047)4.92006935
17glutamate receptor signaling pathway (GO:0007215)4.90077909
18neuron cell-cell adhesion (GO:0007158)4.78542772
19synaptic transmission, glutamatergic (GO:0035249)4.74335998
20dendritic spine morphogenesis (GO:0060997)4.69315511
21neuronal action potential propagation (GO:0019227)4.60544769
22synaptic vesicle docking involved in exocytosis (GO:0016081)4.58807924
23regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.50088824
24regulation of synaptic vesicle exocytosis (GO:2000300)4.45416209
25axon ensheathment in central nervous system (GO:0032291)4.32894684
26central nervous system myelination (GO:0022010)4.32894684
27long-term memory (GO:0007616)4.29684701
28neuron-neuron synaptic transmission (GO:0007270)4.27745500
29regulation of excitatory postsynaptic membrane potential (GO:0060079)4.25504275
30neurotransmitter-gated ion channel clustering (GO:0072578)4.22371566
31regulation of synapse structural plasticity (GO:0051823)4.18812316
32neurotransmitter secretion (GO:0007269)4.15441707
33regulation of dendritic spine morphogenesis (GO:0061001)4.12476820
34positive regulation of membrane potential (GO:0045838)4.11525688
35cellular potassium ion homeostasis (GO:0030007)4.10559767
36layer formation in cerebral cortex (GO:0021819)4.10372043
37regulation of synaptic vesicle transport (GO:1902803)4.07432696
38neuron recognition (GO:0008038)4.01865916
39regulation of postsynaptic membrane potential (GO:0060078)4.01339884
40regulation of synaptic plasticity (GO:0048167)3.99700673
41membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.94357703
42potassium ion homeostasis (GO:0055075)3.92692660
43G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.92049875
44sodium ion export (GO:0071436)3.92010672
45proline transport (GO:0015824)3.91163908
46gamma-aminobutyric acid transport (GO:0015812)3.86742940
47dendritic spine organization (GO:0097061)3.81157934
48positive regulation of synapse maturation (GO:0090129)3.80841438
49pyrimidine nucleobase catabolic process (GO:0006208)3.79722681
50startle response (GO:0001964)3.74122906
51gamma-aminobutyric acid signaling pathway (GO:0007214)3.72053703
52collecting duct development (GO:0072044)3.71187102
53postsynaptic membrane organization (GO:0001941)3.66344588
54innervation (GO:0060384)3.65991999
55transmission of nerve impulse (GO:0019226)3.64775484
56axonal fasciculation (GO:0007413)3.64399266
57behavioral defense response (GO:0002209)3.62074526
58behavioral fear response (GO:0001662)3.62074526
59positive regulation of dendritic spine development (GO:0060999)3.60906893
60positive regulation of dendritic spine morphogenesis (GO:0061003)3.60634608
61long-term synaptic potentiation (GO:0060291)3.60024119
62positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.57084061
63cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.56557336
64response to histamine (GO:0034776)3.54895988
65positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.54155978
66cell communication by electrical coupling (GO:0010644)3.54145231
67synaptic vesicle endocytosis (GO:0048488)3.49806464
68neuromuscular process controlling balance (GO:0050885)3.48423974
69regulation of dendritic spine development (GO:0060998)3.46996303
70positive regulation of synaptic transmission, GABAergic (GO:0032230)3.46241615
71regulation of synaptic transmission, glutamatergic (GO:0051966)3.43873230
72establishment of mitochondrion localization (GO:0051654)3.43397057
73neurotransmitter transport (GO:0006836)3.42091402
74negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41830440
75nucleobase catabolic process (GO:0046113)3.41707763
76epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.40623386
77fear response (GO:0042596)3.39443178
78neuromuscular synaptic transmission (GO:0007274)3.37981897
79L-amino acid import (GO:0043092)3.37832739
80chemosensory behavior (GO:0007635)3.37302381
81learning (GO:0007612)3.36603626
82regulation of vesicle fusion (GO:0031338)3.36045692
83potassium ion import (GO:0010107)3.33893292
84regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.32684534
85G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.32566442
86positive regulation of neurotransmitter secretion (GO:0001956)3.31587353
87membrane depolarization (GO:0051899)3.28992249
88cornea development in camera-type eye (GO:0061303)3.28554848
89presynaptic membrane assembly (GO:0097105)3.25444314
90regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.24796418
91mechanosensory behavior (GO:0007638)3.21671810
92regulation of glutamate secretion (GO:0014048)3.18910493
93regulation of neurotransmitter levels (GO:0001505)3.18646842
94activation of protein kinase A activity (GO:0034199)3.17598710
95regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.17204382
96regulation of female receptivity (GO:0045924)3.15469636
97nephron tubule morphogenesis (GO:0072078)3.14764564
98nephron epithelium morphogenesis (GO:0072088)3.14764564
99regulation of synaptic transmission (GO:0050804)3.13949991
100regulation of neurotransmitter secretion (GO:0046928)3.13637629
101intraspecies interaction between organisms (GO:0051703)3.12789774
102social behavior (GO:0035176)3.12789774
103cellular sodium ion homeostasis (GO:0006883)3.12748776
104neuronal ion channel clustering (GO:0045161)3.12702283
105auditory behavior (GO:0031223)3.10098283
106positive regulation of neurotransmitter transport (GO:0051590)3.07822995
107regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.07458664
108response to auditory stimulus (GO:0010996)3.05996819
109establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.05425831
110mitochondrion transport along microtubule (GO:0047497)3.05425831
111opioid receptor signaling pathway (GO:0038003)3.04778806
112positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.04528650
113dendrite morphogenesis (GO:0048813)3.03862775
114positive regulation of synaptic transmission (GO:0050806)3.02493110
115neuromuscular process controlling posture (GO:0050884)3.02132718
116* synaptic transmission (GO:0007268)3.00016411
117regulation of synapse maturation (GO:0090128)2.99421357
118adult walking behavior (GO:0007628)2.97799227
119membrane depolarization during action potential (GO:0086010)2.97740281
120presynaptic membrane organization (GO:0097090)2.97386569
121cerebellar Purkinje cell differentiation (GO:0021702)2.95792032
122synapse assembly (GO:0007416)2.94586190
123negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.93554939
124positive regulation of synapse assembly (GO:0051965)2.92268181
125positive regulation of potassium ion transmembrane transport (GO:1901381)2.91464538
126regulation of respiratory system process (GO:0044065)2.87518494
127membrane hyperpolarization (GO:0060081)2.79175936
128regulation of voltage-gated calcium channel activity (GO:1901385)2.78958886
129neuronal action potential (GO:0019228)2.77334328
130calcium ion-dependent exocytosis (GO:0017156)2.76085561
131regulation of neurotransmitter transport (GO:0051588)2.73850227
132cell migration in hindbrain (GO:0021535)2.71671454
133regulation of calcium ion-dependent exocytosis (GO:0017158)2.63600779
134adult behavior (GO:0030534)2.63243610

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.79451616
2GBX2_23144817_ChIP-Seq_PC3_Human3.47408854
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.43343508
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.33071496
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.25884521
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.94014120
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.94014120
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.90778868
9REST_21632747_ChIP-Seq_MESCs_Mouse2.86043816
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.85568940
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.79616685
12* RARB_27405468_Chip-Seq_BRAIN_Mouse2.76146354
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.67524735
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.66338396
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.63187484
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61556520
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.51483080
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.46568233
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.42884396
20DROSHA_22980978_ChIP-Seq_HELA_Human2.40574856
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.38334828
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.37930577
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.32616185
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.21214722
25* IKZF1_21737484_ChIP-ChIP_HCT116_Human2.17059172
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.15648989
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.93392943
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.89654234
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89172295
30AR_21572438_ChIP-Seq_LNCaP_Human1.79750223
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71770683
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69246522
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.68198377
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.58958587
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.55205596
36SMAD4_21799915_ChIP-Seq_A2780_Human1.53279150
37* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52668202
38ZNF274_21170338_ChIP-Seq_K562_Hela1.50378668
39RING1B_27294783_Chip-Seq_ESCs_Mouse1.46509003
40RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44619973
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38774420
42TAF15_26573619_Chip-Seq_HEK293_Human1.35805793
43RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.34488395
44P300_19829295_ChIP-Seq_ESCs_Human1.33445888
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31524405
46ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29896777
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28190025
48DNAJC2_21179169_ChIP-ChIP_NT2_Human1.27029760
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.26558967
50NR3C1_23031785_ChIP-Seq_PC12_Mouse1.25629276
51CBX2_27304074_Chip-Seq_ESCs_Mouse1.23634979
52AR_25329375_ChIP-Seq_VCAP_Human1.23018705
53SOX2_21211035_ChIP-Seq_LN229_Gbm1.21979151
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21357671
55RING1B_27294783_Chip-Seq_NPCs_Mouse1.20419349
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18355083
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.17706096
58AR_19668381_ChIP-Seq_PC3_Human1.16322794
59PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13416686
60ZFP281_18757296_ChIP-ChIP_E14_Mouse1.12578901
61CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12168122
62WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12137358
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.10941173
64IGF1R_20145208_ChIP-Seq_DFB_Human1.10575012
65TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10070154
66ER_23166858_ChIP-Seq_MCF-7_Human1.09786635
67WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09653652
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09479883
69TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09285903
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08493478
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07965329
72STAT3_23295773_ChIP-Seq_U87_Human1.06628576
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05790382
74CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05041909
75BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04700538
76* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.04206031
77KDM2B_26808549_Chip-Seq_K562_Human1.03333562
78TP53_16413492_ChIP-PET_HCT116_Human1.02423599
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.02226292
80SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02079324
81ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.00743913
82TP53_22573176_ChIP-Seq_HFKS_Human1.00716165
83RNF2_27304074_Chip-Seq_NSC_Mouse1.00465210
84GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00228521
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00108855
86PIAS1_25552417_ChIP-Seq_VCAP_Human0.99827157
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99704225
88CBP_20019798_ChIP-Seq_JUKART_Human0.99277869
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.99277869
90RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99074355
91FUS_26573619_Chip-Seq_HEK293_Human0.98663460
92RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98602051
93MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98347115
94TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.96939756
95PRDM14_20953172_ChIP-Seq_ESCs_Human0.96697130
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96533499
97CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96083960
98TCF4_23295773_ChIP-Seq_U87_Human0.96025732
99P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94692917
100YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94163094
101EWS_26573619_Chip-Seq_HEK293_Human0.93931062
102CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93892061
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93557183
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.93557183
105BCAT_22108803_ChIP-Seq_LS180_Human0.93492874
106SMAD3_21741376_ChIP-Seq_HESCs_Human0.93049362
107VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92647062
108ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92457055
109EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.92347682
110SMAD3_21741376_ChIP-Seq_ESCs_Human0.92233757
111SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92118882
112UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91619440
113ARNT_22903824_ChIP-Seq_MCF-7_Human0.91482544
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91096801
115TP53_20018659_ChIP-ChIP_R1E_Mouse0.90568629
116TCF4_22108803_ChIP-Seq_LS180_Human0.89580379
117ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88802265
118CTCF_27219007_Chip-Seq_Bcells_Human0.88568388
119RUNX2_22187159_ChIP-Seq_PCA_Human0.88547639
120TP53_18474530_ChIP-ChIP_U2OS_Human0.87622085
121SMAD4_21741376_ChIP-Seq_HESCs_Human0.87204568
122JUN_21703547_ChIP-Seq_K562_Human0.85816193
123VDR_22108803_ChIP-Seq_LS180_Human0.85708279
124ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.84149414
125THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83449460
126CDX2_19796622_ChIP-Seq_MESCs_Mouse0.83448391

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.53616384
2MP0003880_abnormal_central_pattern5.50922071
3* MP0003635_abnormal_synaptic_transmissio4.40641729
4MP0009745_abnormal_behavioral_response3.68653377
5MP0004270_analgesia3.66522404
6MP0002063_abnormal_learning/memory/cond3.63671608
7MP0002064_seizures3.29334479
8MP0002572_abnormal_emotion/affect_behav2.93471656
9MP0001968_abnormal_touch/_nociception2.87785269
10MP0002822_catalepsy2.86732703
11MP0009046_muscle_twitch2.74785991
12MP0005423_abnormal_somatic_nervous2.71528220
13MP0001486_abnormal_startle_reflex2.63225105
14MP0002272_abnormal_nervous_system2.62254776
15MP0002734_abnormal_mechanical_nocicepti2.40979199
16MP0002735_abnormal_chemical_nociception2.39933881
17MP0001501_abnormal_sleep_pattern2.38255954
18MP0002736_abnormal_nociception_after2.32307842
19MP0002638_abnormal_pupillary_reflex2.30029295
20MP0001440_abnormal_grooming_behavior2.27663961
21MP0004858_abnormal_nervous_system2.26588316
22MP0009780_abnormal_chondrocyte_physiolo2.07013215
23MP0003329_amyloid_beta_deposits1.99069669
24MP0002733_abnormal_thermal_nociception1.87369285
25MP0000778_abnormal_nervous_system1.86552761
26MP0001970_abnormal_pain_threshold1.86265846
27MP0002067_abnormal_sensory_capabilities1.82164959
28MP0008877_abnormal_DNA_methylation1.76321349
29MP0008569_lethality_at_weaning1.75759276
30MP0002184_abnormal_innervation1.75518366
31MP0002557_abnormal_social/conspecific_i1.75055702
32MP0004811_abnormal_neuron_physiology1.73647400
33MP0003123_paternal_imprinting1.70748325
34MP0003121_genomic_imprinting1.70230727
35MP0004885_abnormal_endolymph1.62071939
36MP0003879_abnormal_hair_cell1.56748931
37MP0004924_abnormal_behavior1.54934163
38MP0005386_behavior/neurological_phenoty1.54934163
39MP0000955_abnormal_spinal_cord1.53933264
40MP0006276_abnormal_autonomic_nervous1.51564673
41MP0002909_abnormal_adrenal_gland1.49062448
42MP0005646_abnormal_pituitary_gland1.46278839
43MP0004133_heterotaxia1.45064838
44MP0002066_abnormal_motor_capabilities/c1.41797632
45MP0001529_abnormal_vocalization1.40631248
46* MP0002882_abnormal_neuron_morphology1.39246550
47MP0000569_abnormal_digit_pigmentation1.37155609
48MP0001984_abnormal_olfaction1.31954751
49MP0003787_abnormal_imprinting1.31017514
50MP0003633_abnormal_nervous_system1.30718680
51MP0001905_abnormal_dopamine_level1.29288098
52MP0004142_abnormal_muscle_tone1.28964598
53MP0006072_abnormal_retinal_apoptosis1.28667350
54MP0005645_abnormal_hypothalamus_physiol1.25501759
55MP0003075_altered_response_to1.24398284
56MP0003136_yellow_coat_color1.19711852
57MP0001502_abnormal_circadian_rhythm1.17464767
58MP0004147_increased_porphyrin_level1.15993376
59MP0003631_nervous_system_phenotype1.13729734
60* MP0002152_abnormal_brain_morphology1.11017405
61MP0002102_abnormal_ear_morphology1.10002657
62MP0003011_delayed_dark_adaptation1.07370059
63MP0001986_abnormal_taste_sensitivity1.06983145
64MP0010386_abnormal_urinary_bladder1.03420064
65MP0001188_hyperpigmentation0.96064402
66MP0002069_abnormal_eating/drinking_beha0.95422128
67MP0001177_atelectasis0.94632202
68MP0002928_abnormal_bile_duct0.93733313
69MP0000604_amyloidosis0.91867290
70MP0008872_abnormal_physiological_respon0.91421127
71MP0005253_abnormal_eye_physiology0.89693203
72MP0003122_maternal_imprinting0.89092283
73MP0003690_abnormal_glial_cell0.88566447
74MP0008874_decreased_physiological_sensi0.87719650
75MP0002229_neurodegeneration0.86548332
76MP0003634_abnormal_glial_cell0.86484209
77MP0000751_myopathy0.85863800
78MP0001963_abnormal_hearing_physiology0.84275384
79MP0004510_myositis0.84022936
80MP0003632_abnormal_nervous_system0.83383797
81MP0005195_abnormal_posterior_eye0.83075259
82MP0002837_dystrophic_cardiac_calcinosis0.82792943
83MP0003878_abnormal_ear_physiology0.82102077
84MP0005377_hearing/vestibular/ear_phenot0.82102077
85MP0005409_darkened_coat_color0.80553722
86MP0005535_abnormal_body_temperature0.79615617
87MP0000920_abnormal_myelination0.77738309
88MP0004085_abnormal_heartbeat0.77493180
89MP0002653_abnormal_ependyma_morphology0.76735931
90MP0005394_taste/olfaction_phenotype0.75737096
91MP0005499_abnormal_olfactory_system0.75737096
92MP0004043_abnormal_pH_regulation0.74953228
93MP0005174_abnormal_tail_pigmentation0.74102070
94MP0002249_abnormal_larynx_morphology0.73828609
95MP0005551_abnormal_eye_electrophysiolog0.73586809
96MP0004484_altered_response_of0.71698888
97MP0002163_abnormal_gland_morphology0.70732224
98MP0006292_abnormal_olfactory_placode0.70363069
99MP0002752_abnormal_somatic_nervous0.70356381
100MP0002876_abnormal_thyroid_physiology0.70043663
101MP0004742_abnormal_vestibular_system0.69030097
102MP0004145_abnormal_muscle_electrophysio0.68737025
103MP0001485_abnormal_pinna_reflex0.67443673
104MP0002938_white_spotting0.67375617
105MP0001664_abnormal_digestion0.66547103
106MP0000631_abnormal_neuroendocrine_gland0.65962882
107MP0005167_abnormal_blood-brain_barrier0.64952498
108MP0003137_abnormal_impulse_conducting0.64813146
109MP0003283_abnormal_digestive_organ0.64466330
110MP0005623_abnormal_meninges_morphology0.62024243
111MP0003183_abnormal_peptide_metabolism0.61939713
112MP0002090_abnormal_vision0.61910920
113MP0000013_abnormal_adipose_tissue0.61684199
114MP0008961_abnormal_basal_metabolism0.61258957
115MP0002160_abnormal_reproductive_system0.60286073
116MP0003861_abnormal_nervous_system0.58241742
117MP0004215_abnormal_myocardial_fiber0.57901988
118MP0001943_abnormal_respiration0.53524880
119MP0000026_abnormal_inner_ear0.52237012
120MP0002234_abnormal_pharynx_morphology0.51675210
121MP0010234_abnormal_vibrissa_follicle0.49874169
122MP0010769_abnormal_survival0.49015247
123MP0003938_abnormal_ear_development0.47473907
124MP0003956_abnormal_body_size0.46182950
125MP0005410_abnormal_fertilization0.46156933

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.42800339
2Myokymia (HP:0002411)7.78663675
3Focal seizures (HP:0007359)6.01370292
4Visual hallucinations (HP:0002367)5.72810243
5Atonic seizures (HP:0010819)4.87388827
6Epileptic encephalopathy (HP:0200134)4.72904158
7Febrile seizures (HP:0002373)4.67862826
8Absence seizures (HP:0002121)4.41406162
9Progressive cerebellar ataxia (HP:0002073)4.25535900
10Generalized tonic-clonic seizures (HP:0002069)4.14790638
11Dialeptic seizures (HP:0011146)4.12710757
12Action tremor (HP:0002345)3.92239767
13Supranuclear gaze palsy (HP:0000605)3.81895776
14Impaired vibration sensation in the lower limbs (HP:0002166)3.67471614
15Limb dystonia (HP:0002451)3.50847636
16Amblyopia (HP:0000646)3.46590010
17Cerebral inclusion bodies (HP:0100314)3.45432521
18Broad-based gait (HP:0002136)3.45375858
19Depression (HP:0000716)3.37278727
20Hyperventilation (HP:0002883)3.34174187
21Dysmetria (HP:0001310)3.28341475
22Neurofibrillary tangles (HP:0002185)3.24713900
23Abnormality of the lower motor neuron (HP:0002366)3.21952792
24Dysdiadochokinesis (HP:0002075)3.18669934
25Anxiety (HP:0000739)3.16292532
26Poor eye contact (HP:0000817)3.16265508
27Postural instability (HP:0002172)3.12844954
28Mutism (HP:0002300)3.12706152
29Hemiparesis (HP:0001269)3.11323457
30Gaze-evoked nystagmus (HP:0000640)3.06226242
31Abnormality of midbrain morphology (HP:0002418)3.05257267
32Molar tooth sign on MRI (HP:0002419)3.05257267
33Diplopia (HP:0000651)3.02428020
34Abnormality of binocular vision (HP:0011514)3.02428020
35Abnormal eating behavior (HP:0100738)2.96120420
36Drooling (HP:0002307)2.95089017
37Excessive salivation (HP:0003781)2.95089017
38Pancreatic cysts (HP:0001737)2.94939766
39Truncal ataxia (HP:0002078)2.92845714
40Urinary bladder sphincter dysfunction (HP:0002839)2.92289812
41Ankle clonus (HP:0011448)2.86853246
42Impaired social interactions (HP:0000735)2.83122223
43Abnormal social behavior (HP:0012433)2.83122223
44Nephronophthisis (HP:0000090)2.80566688
45Congenital stationary night blindness (HP:0007642)2.79367024
46Pancreatic fibrosis (HP:0100732)2.79191738
47Septo-optic dysplasia (HP:0100842)2.74953609
48Megalencephaly (HP:0001355)2.66396442
49Hemiplegia (HP:0002301)2.66287244
50Polydipsia (HP:0001959)2.64359139
51Abnormal drinking behavior (HP:0030082)2.64359139
52Focal dystonia (HP:0004373)2.59681910
53Torticollis (HP:0000473)2.55546943
54Papilledema (HP:0001085)2.53916986
55Urinary urgency (HP:0000012)2.53552068
56Stereotypic behavior (HP:0000733)2.53467366
57Prolonged QT interval (HP:0001657)2.52139981
58Abnormality of the renal medulla (HP:0100957)2.51741103
59Bradykinesia (HP:0002067)2.51656878
60Spastic gait (HP:0002064)2.51520842
61Impaired smooth pursuit (HP:0007772)2.50847998
62Intention tremor (HP:0002080)2.50496964
63Progressive inability to walk (HP:0002505)2.49529632
64Epileptiform EEG discharges (HP:0011182)2.47999343
65Annular pancreas (HP:0001734)2.42300966
66Delusions (HP:0000746)2.41784933
67Optic nerve hypoplasia (HP:0000609)2.41737316
68Supernumerary spleens (HP:0009799)2.41659671
69Genetic anticipation (HP:0003743)2.40569147
70Gait imbalance (HP:0002141)2.39016125
71Type II lissencephaly (HP:0007260)2.37399524
72Asplenia (HP:0001746)2.37212190
73Aplasia/Hypoplasia of the spleen (HP:0010451)2.36437247
74Impaired vibratory sensation (HP:0002495)2.35824663
75Absent speech (HP:0001344)2.35668160
76Ventricular fibrillation (HP:0001663)2.34025882
77EEG with generalized epileptiform discharges (HP:0011198)2.28033573
78Cystic liver disease (HP:0006706)2.25038402
79Pachygyria (HP:0001302)2.23271752
80Generalized myoclonic seizures (HP:0002123)2.22995057
81Absent rod-and cone-mediated responses on ERG (HP:0007688)2.21763637
82Fetal akinesia sequence (HP:0001989)2.21520031
83Abnormality of the corticospinal tract (HP:0002492)2.19446718
84Incomplete penetrance (HP:0003829)2.18085814
85Agitation (HP:0000713)2.18002555
86Protruding tongue (HP:0010808)2.17643388
87Abnormality of ocular smooth pursuit (HP:0000617)2.16482214
88Scanning speech (HP:0002168)2.15443303
89Hypsarrhythmia (HP:0002521)2.14949223
90Medial flaring of the eyebrow (HP:0010747)2.14240278
91Oligodactyly (hands) (HP:0001180)2.14165700
92Abnormal rod and cone electroretinograms (HP:0008323)2.13977258
93Degeneration of the lateral corticospinal tracts (HP:0002314)2.13743191
94Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.13743191
95Craniofacial dystonia (HP:0012179)2.13545294
96Obstructive sleep apnea (HP:0002870)2.12058202
97Lower limb asymmetry (HP:0100559)2.11334997
98Status epilepticus (HP:0002133)2.11022171
99Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.10632411
100Insidious onset (HP:0003587)2.10350663
101Termporal pattern (HP:0011008)2.10350663
102Abnormality of the renal cortex (HP:0011035)2.10272069
103True hermaphroditism (HP:0010459)2.10101702
104Ulnar claw (HP:0001178)2.09257618
105Lower limb muscle weakness (HP:0007340)2.08167901
106Abnormality of salivation (HP:0100755)2.06293337
107Amyotrophic lateral sclerosis (HP:0007354)2.05817596
108Abnormal EKG (HP:0003115)2.05088531
109Abnormality of the labia minora (HP:0012880)2.03245927
110Pointed chin (HP:0000307)2.02552017
111Acute necrotizing encephalopathy (HP:0006965)2.00471172
112Polyphagia (HP:0002591)1.99856583
113Inability to walk (HP:0002540)1.99529803
114Aplasia involving bones of the extremities (HP:0009825)1.99337404
115Aplasia involving bones of the upper limbs (HP:0009823)1.99337404
116Aplasia of the phalanges of the hand (HP:0009802)1.99337404
117Apathy (HP:0000741)1.97876207
118Rapidly progressive (HP:0003678)1.97458098
119Thyroid-stimulating hormone excess (HP:0002925)1.93644829
120Polyuria (HP:0000103)1.91654286
121Tubular atrophy (HP:0000092)1.90550478
122Gait ataxia (HP:0002066)1.90338110
123Insomnia (HP:0100785)1.89605083
124Abolished electroretinogram (ERG) (HP:0000550)1.88663521
125Decreased central vision (HP:0007663)1.87986905
126Bile duct proliferation (HP:0001408)1.86835507
127Abnormal biliary tract physiology (HP:0012439)1.86835507
128Dysmetric saccades (HP:0000641)1.86270622
129Anosmia (HP:0000458)1.84259980
130Lissencephaly (HP:0001339)1.83856274
131Neuronal loss in central nervous system (HP:0002529)1.83563035
132Severe muscular hypotonia (HP:0006829)1.82052367
133Psychosis (HP:0000709)1.81676618
134Specific learning disability (HP:0001328)1.81075897
135Akinesia (HP:0002304)1.80728374
136Morphological abnormality of the pyramidal tract (HP:0002062)1.79124249
137Symphalangism affecting the phalanges of the hand (HP:0009773)1.79086123
138Hepatocellular necrosis (HP:0001404)1.77973778
139Progressive macrocephaly (HP:0004481)1.77660896
140Cerebral hypomyelination (HP:0006808)1.77111097
141Thickened helices (HP:0000391)1.77109617
142Mitochondrial inheritance (HP:0001427)1.76798931
143Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.76753689
144Decreased electroretinogram (ERG) amplitude (HP:0000654)1.76122484
145Increased circulating renin level (HP:0000848)1.76103063
146Ankyloglossia (HP:0010296)1.75483990
147Rigidity (HP:0002063)1.74931135
148Syncope (HP:0001279)1.74403090
149Dynein arm defect of respiratory motile cilia (HP:0012255)1.73833862
150Absent/shortened dynein arms (HP:0200106)1.73833862
151Diminished motivation (HP:0000745)1.72866626
152Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.72652955
153Lower limb amyotrophy (HP:0007210)1.72476519
154Congenital primary aphakia (HP:0007707)1.72120254
155Hydroureter (HP:0000072)1.71122971
156Retinal dysplasia (HP:0007973)1.68774423
157Attenuation of retinal blood vessels (HP:0007843)1.67489927
158Sleep apnea (HP:0010535)1.65037806

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.68509226
2NTRK34.83427305
3MAP3K93.62853380
4WNK43.28320634
5FRK2.74514272
6MINK12.63803779
7MAP3K42.58465712
8MARK12.57976212
9STK392.49072601
10PRKD32.43009001
11RIPK42.35302921
12KSR22.30459230
13NTRK22.25214197
14DAPK22.25164973
15CAMK1D2.23334367
16MAP2K72.19319379
17PAK62.18599064
18NTRK11.92669733
19KSR11.80671781
20ARAF1.76494550
21MAP3K121.74499651
22PLK21.74119229
23PNCK1.69791938
24MAP3K131.68954853
25BMPR1B1.68128532
26PRPF4B1.66688110
27DAPK11.63912884
28CAMKK11.61865938
29CDK51.60778861
30FES1.58622180
31GRK51.55930143
32MAP2K41.54174635
33SIK21.51669914
34CASK1.50186475
35ADRBK21.49585412
36DYRK21.42583219
37TNIK1.40590982
38PRKCG1.37552631
39STK381.30821693
40PTK2B1.27730130
41CAMK2A1.15517587
42MAPK131.14529939
43TAOK31.13610060
44TYRO31.10475465
45RAF11.07948740
46PKN11.07452279
47NME11.07235700
48CAMK2B1.07109718
49WNK11.03399844
50UHMK11.02192573
51BMPR21.00215192
52MKNK21.00080817
53MAP3K20.98866033
54CAMK10.97838775
55MAP4K20.96463553
56GRK10.96122713
57LATS20.95650228
58FGR0.94629100
59CDK190.92800697
60CDK180.87710984
61CDK150.87286397
62MAPK120.82871558
63INSRR0.82264597
64CDK140.81602633
65DYRK1A0.79315790
66STK110.78881875
67CDK11A0.75851142
68BCKDK0.75186403
69PAK30.74107118
70PHKG10.73999096
71PHKG20.73999096
72FGFR20.71764800
73CDC70.70364055
74PRKCH0.69706090
75SGK10.69528791
76SGK4940.67477389
77SGK2230.67477389
78ADRBK10.66665737
79PDK10.65110963
80TAOK10.64427983
81ALK0.63463364
82TRIM280.62735585
83ZAK0.62269423
84LMTK20.62222752
85NEK60.59105190
86PINK10.56618891
87PDPK10.56278815
88FER0.56227147
89TIE10.54284956
90PRKCE0.54175784
91MAP3K10.54040541
92SGK20.53820413
93MARK20.53690366
94PRKCZ0.53598400
95MAP3K70.52210659
96RET0.51977612
97CAMKK20.50430789
98CAMK2D0.48801672
99TLK10.48132252
100CSNK1E0.48111930
101TNK20.47372498
102RPS6KA30.47301960
103STK160.46417740
104CAMK2G0.46067591
105OXSR10.46031163
106FYN0.45852428
107PRKCQ0.45556881
108PRKACA0.45329987
109CSNK1G20.45054334
110SGK30.45036688
111MAPK100.43092050
112MAP2K10.42584821
113PIK3CA0.41896183
114PRKG10.41597401
115ROCK20.40844742
116DDR20.39473608
117BRAF0.39394243
118CAMK40.39172655
119PRKAA10.37898078
120CCNB10.37897563
121BRSK10.36526892
122MOS0.36285507
123DAPK30.36149757
124PRKCI0.35096142
125CSNK1G30.34854016
126CSNK1G10.34380251
127GRK60.33897927
128CAMK1G0.33790116
129ACVR1B0.33635353
130PRKCA0.33601636
131BCR0.32685002
132PRKCB0.32052098
133CSNK1A10.31989662
134PRKD20.30996627
135MUSK0.30803756
136CDC42BPA0.30569853
137WNK30.30299807
138ERBB20.29920017

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.12459218
2Synaptic vesicle cycle_Homo sapiens_hsa047213.00676927
3Long-term potentiation_Homo sapiens_hsa047202.98689278
4Olfactory transduction_Homo sapiens_hsa047402.86511503
5Circadian entrainment_Homo sapiens_hsa047132.77903535
6Glutamatergic synapse_Homo sapiens_hsa047242.76855784
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76483908
8GABAergic synapse_Homo sapiens_hsa047272.67164638
9Amphetamine addiction_Homo sapiens_hsa050312.63743021
10Morphine addiction_Homo sapiens_hsa050322.48781736
11Salivary secretion_Homo sapiens_hsa049702.41503108
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.28803001
13Dopaminergic synapse_Homo sapiens_hsa047282.08452279
14Gastric acid secretion_Homo sapiens_hsa049712.06036386
15Insulin secretion_Homo sapiens_hsa049111.97041726
16Cholinergic synapse_Homo sapiens_hsa047251.91509234
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.88712364
18Taste transduction_Homo sapiens_hsa047421.82444528
19Calcium signaling pathway_Homo sapiens_hsa040201.81933169
20Long-term depression_Homo sapiens_hsa047301.70424551
21Renin secretion_Homo sapiens_hsa049241.69031529
22Serotonergic synapse_Homo sapiens_hsa047261.68508963
23* Oxytocin signaling pathway_Homo sapiens_hsa049211.65796259
24* Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.64640735
25Cocaine addiction_Homo sapiens_hsa050301.50699627
26Parkinsons disease_Homo sapiens_hsa050121.49802197
27GnRH signaling pathway_Homo sapiens_hsa049121.49004490
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.47282619
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.42680083
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39865619
31Collecting duct acid secretion_Homo sapiens_hsa049661.39222597
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38566551
33Gap junction_Homo sapiens_hsa045401.35731856
34Linoleic acid metabolism_Homo sapiens_hsa005911.32593425
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.31924329
36cAMP signaling pathway_Homo sapiens_hsa040241.30474490
37Ether lipid metabolism_Homo sapiens_hsa005651.26139385
38Glioma_Homo sapiens_hsa052141.23364713
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22764154
40Axon guidance_Homo sapiens_hsa043601.22646831
41Butanoate metabolism_Homo sapiens_hsa006501.20445999
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.16716824
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16280235
44Melanogenesis_Homo sapiens_hsa049161.15299060
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.15200802
46Estrogen signaling pathway_Homo sapiens_hsa049151.12897052
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10633065
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.08872847
49cGMP-PKG signaling pathway_Homo sapiens_hsa040221.08358849
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06846078
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05707621
52* Cardiac muscle contraction_Homo sapiens_hsa042601.04376133
53Type II diabetes mellitus_Homo sapiens_hsa049301.01459763
54ErbB signaling pathway_Homo sapiens_hsa040120.99448921
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98680583
56Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98225099
57Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.96349226
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.96142724
59Huntingtons disease_Homo sapiens_hsa050160.93965859
60Nitrogen metabolism_Homo sapiens_hsa009100.91013196
61Pancreatic secretion_Homo sapiens_hsa049720.90197540
62Vibrio cholerae infection_Homo sapiens_hsa051100.86659820
63beta-Alanine metabolism_Homo sapiens_hsa004100.86185242
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.86068983
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.84511109
66Oocyte meiosis_Homo sapiens_hsa041140.84390637
67Homologous recombination_Homo sapiens_hsa034400.81285407
68Thyroid hormone synthesis_Homo sapiens_hsa049180.78992429
69Choline metabolism in cancer_Homo sapiens_hsa052310.76847533
70Protein export_Homo sapiens_hsa030600.72975950
71Phototransduction_Homo sapiens_hsa047440.71533600
72Propanoate metabolism_Homo sapiens_hsa006400.70400031
73VEGF signaling pathway_Homo sapiens_hsa043700.69940684
74Dorso-ventral axis formation_Homo sapiens_hsa043200.69368184
75Regulation of autophagy_Homo sapiens_hsa041400.68476408
76Hedgehog signaling pathway_Homo sapiens_hsa043400.68134782
77Glucagon signaling pathway_Homo sapiens_hsa049220.61087111
78* Dilated cardiomyopathy_Homo sapiens_hsa054140.60874370
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60721950
80Alzheimers disease_Homo sapiens_hsa050100.60456357
81* MAPK signaling pathway_Homo sapiens_hsa040100.60383606
82Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59445047
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.59375267
84African trypanosomiasis_Homo sapiens_hsa051430.59115813
85Histidine metabolism_Homo sapiens_hsa003400.58835293
86Peroxisome_Homo sapiens_hsa041460.58727892
87Type I diabetes mellitus_Homo sapiens_hsa049400.58574874
88Vitamin B6 metabolism_Homo sapiens_hsa007500.58573244
89Rap1 signaling pathway_Homo sapiens_hsa040150.58224587
90Ras signaling pathway_Homo sapiens_hsa040140.56633284
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.56137352
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54183660
93Bile secretion_Homo sapiens_hsa049760.53011943
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.51882957
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49822200
96Caffeine metabolism_Homo sapiens_hsa002320.49197436
97Prion diseases_Homo sapiens_hsa050200.48699480
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47730590
99Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47001987
100Wnt signaling pathway_Homo sapiens_hsa043100.45488054
101Alcoholism_Homo sapiens_hsa050340.45368793
102Endocytosis_Homo sapiens_hsa041440.42434226
103Non-small cell lung cancer_Homo sapiens_hsa052230.40485865
104mTOR signaling pathway_Homo sapiens_hsa041500.39741496
105Basal cell carcinoma_Homo sapiens_hsa052170.39329447
106Inositol phosphate metabolism_Homo sapiens_hsa005620.39220663
107Maturity onset diabetes of the young_Homo sapiens_hsa049500.37738237
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.37593813
109Steroid biosynthesis_Homo sapiens_hsa001000.37184691
110Tryptophan metabolism_Homo sapiens_hsa003800.36818300
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.35098754
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34577033
113Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33861196
114Glycerolipid metabolism_Homo sapiens_hsa005610.33710197
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33101652
116Basal transcription factors_Homo sapiens_hsa030220.32912695
117Oxidative phosphorylation_Homo sapiens_hsa001900.32831835
118* Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.31414969
119Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30529023
120Hippo signaling pathway_Homo sapiens_hsa043900.30484773
121Selenocompound metabolism_Homo sapiens_hsa004500.29228995
122Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.29085181
123Chemokine signaling pathway_Homo sapiens_hsa040620.28268807
124Renal cell carcinoma_Homo sapiens_hsa052110.26525196
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26423417
126Ovarian steroidogenesis_Homo sapiens_hsa049130.26372661
127Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.25740375
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.25679621
129Mineral absorption_Homo sapiens_hsa049780.25311267
130Endometrial cancer_Homo sapiens_hsa052130.25112206
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24995919
132Insulin signaling pathway_Homo sapiens_hsa049100.24916169
133Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23582830

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