CACNG5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)8.30075544
2nucleobase catabolic process (GO:0046113)6.41510900
3locomotory exploration behavior (GO:0035641)6.24657562
4neuron cell-cell adhesion (GO:0007158)5.77820020
5vocalization behavior (GO:0071625)5.33178925
6regulation of short-term neuronal synaptic plasticity (GO:0048172)5.20114121
7* regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.92339732
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.89859178
9exploration behavior (GO:0035640)4.76824765
10synaptic vesicle maturation (GO:0016188)4.66683269
11protein localization to synapse (GO:0035418)4.66596415
12gamma-aminobutyric acid transport (GO:0015812)4.64872575
13postsynaptic membrane organization (GO:0001941)4.64575045
14neuronal action potential propagation (GO:0019227)4.58237143
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.53246939
16synaptic vesicle exocytosis (GO:0016079)4.52709362
17* regulation of glutamate receptor signaling pathway (GO:1900449)4.48378501
18neuronal ion channel clustering (GO:0045161)4.45930838
19regulation of synaptic vesicle exocytosis (GO:2000300)4.45420443
20positive regulation of potassium ion transmembrane transporter activity (GO:1901018)4.40545813
21neurotransmitter secretion (GO:0007269)4.37350014
22ionotropic glutamate receptor signaling pathway (GO:0035235)4.35168246
23cerebellar granule cell differentiation (GO:0021707)4.33247486
24neuron projection extension involved in neuron projection guidance (GO:1902284)4.26447520
25axon extension involved in axon guidance (GO:0048846)4.26447520
26mechanosensory behavior (GO:0007638)4.21726836
27presynaptic membrane assembly (GO:0097105)4.19752665
28proline transport (GO:0015824)4.19364988
29establishment of mitochondrion localization (GO:0051654)4.07389964
30glutamate receptor signaling pathway (GO:0007215)4.07293609
31glutamate secretion (GO:0014047)4.03214809
32cellular potassium ion homeostasis (GO:0030007)4.02417906
33regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.01828531
34retinal ganglion cell axon guidance (GO:0031290)4.00230962
35negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.95444293
36layer formation in cerebral cortex (GO:0021819)3.93605960
37regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.91940489
38synaptic transmission, glutamatergic (GO:0035249)3.89585059
39regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.88467378
40neurotransmitter-gated ion channel clustering (GO:0072578)3.86981337
41sodium ion export (GO:0071436)3.82162428
42presynaptic membrane organization (GO:0097090)3.80325862
43regulation of synaptic vesicle transport (GO:1902803)3.79585043
44ganglion development (GO:0061548)3.77480866
45cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.77444574
46positive regulation of synapse assembly (GO:0051965)3.72439097
47cell communication by electrical coupling (GO:0010644)3.69722870
48innervation (GO:0060384)3.69586230
49positive regulation of synaptic transmission, GABAergic (GO:0032230)3.66220268
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.65997700
51neuron-neuron synaptic transmission (GO:0007270)3.64572316
52mitochondrion transport along microtubule (GO:0047497)3.64278529
53establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.64278529
54membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.62104195
55neurotransmitter transport (GO:0006836)3.60653930
56cerebellar Purkinje cell differentiation (GO:0021702)3.56244673
57olfactory bulb development (GO:0021772)3.55829380
58neuron recognition (GO:0008038)3.55632973
59central nervous system projection neuron axonogenesis (GO:0021952)3.53031777
60long-term memory (GO:0007616)3.48801143
61startle response (GO:0001964)3.48239887
62regulation of synapse structural plasticity (GO:0051823)3.45590180
63regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.45340105
64transmission of nerve impulse (GO:0019226)3.43608231
65regulation of neuronal synaptic plasticity (GO:0048168)3.42894557
66synapse assembly (GO:0007416)3.42407777
67positive regulation of potassium ion transmembrane transport (GO:1901381)3.40039075
68cell differentiation in hindbrain (GO:0021533)3.39450787
69neuromuscular process controlling posture (GO:0050884)3.38619754
70behavioral response to nicotine (GO:0035095)3.36775553
71positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.36167015
72positive regulation of synapse maturation (GO:0090129)3.36119877
73regulation of neurotransmitter levels (GO:0001505)3.35314863
74negative regulation of synaptic transmission, GABAergic (GO:0032229)3.34759332
75regulation of respiratory system process (GO:0044065)3.32256710
76dendrite morphogenesis (GO:0048813)3.30502914
77regulation of synaptic transmission, glutamatergic (GO:0051966)3.29968250
78regulation of long-term neuronal synaptic plasticity (GO:0048169)3.29743533
79neuromuscular process controlling balance (GO:0050885)3.28143183
80glycine transport (GO:0015816)3.27969588
81response to pheromone (GO:0019236)3.27732127
82regulation of excitatory postsynaptic membrane potential (GO:0060079)3.26826690
83alanine transport (GO:0032328)3.26574803
84axon extension (GO:0048675)3.26220208
85positive regulation of membrane potential (GO:0045838)3.25449979
86axonal fasciculation (GO:0007413)3.23764360
87activation of protein kinase A activity (GO:0034199)3.23630807
88membrane hyperpolarization (GO:0060081)3.23402579
89cell migration in hindbrain (GO:0021535)3.22114981
90calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.21746294
91membrane depolarization during action potential (GO:0086010)3.21687410
92dendritic spine morphogenesis (GO:0060997)3.21166809
93mating behavior (GO:0007617)3.20017608
94regulation of feeding behavior (GO:0060259)3.19187867
95prepulse inhibition (GO:0060134)3.18714227
96gamma-aminobutyric acid signaling pathway (GO:0007214)3.14739199
97adult walking behavior (GO:0007628)3.14710723
98response to auditory stimulus (GO:0010996)3.13927784
99regulation of postsynaptic membrane potential (GO:0060078)3.13587072
100negative regulation of microtubule polymerization (GO:0031115)3.10995733
101negative regulation of catecholamine secretion (GO:0033604)3.04495697
102negative regulation of axon guidance (GO:1902668)3.03582362
103synapse organization (GO:0050808)3.03431804
104clathrin coat assembly (GO:0048268)3.00805354
105auditory behavior (GO:0031223)3.00765924
106neuromuscular synaptic transmission (GO:0007274)2.99873681
107membrane depolarization (GO:0051899)2.99014050
108regulation of neurotransmitter secretion (GO:0046928)2.98707101
109C4-dicarboxylate transport (GO:0015740)2.97055542
110synaptic vesicle docking involved in exocytosis (GO:0016081)2.96251232
111response to histamine (GO:0034776)2.95755887
112positive regulation of mitochondrial fission (GO:0090141)2.95064508
113neuromuscular process (GO:0050905)2.94007537
114establishment of nucleus localization (GO:0040023)2.93976019
115potassium ion homeostasis (GO:0055075)2.92936030
116regulation of vesicle fusion (GO:0031338)2.92104561
117negative regulation of axon extension involved in axon guidance (GO:0048843)2.91067041
118negative regulation of dendrite development (GO:2000171)2.88416826
119righting reflex (GO:0060013)2.87745812
120forebrain neuron differentiation (GO:0021879)2.86957286
121regulation of respiratory gaseous exchange (GO:0043576)2.86824418
122potassium ion import (GO:0010107)2.86401142
123glycosphingolipid biosynthetic process (GO:0006688)2.86006387
124regulation of cAMP-dependent protein kinase activity (GO:2000479)2.85532033
125protein localization to cilium (GO:0061512)2.83359313
126long-term synaptic potentiation (GO:0060291)2.82788150
127neuron projection extension (GO:1990138)2.81893870
128regulation of synaptic transmission, GABAergic (GO:0032228)2.81496942
129synaptic vesicle endocytosis (GO:0048488)2.81101091
130membrane assembly (GO:0071709)2.80288382
131central nervous system neuron axonogenesis (GO:0021955)2.79560753
132regulation of synapse assembly (GO:0051963)2.79335685
133heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.77363492
134DNA double-strand break processing (GO:0000729)2.77258403
135negative regulation of axon extension (GO:0030517)2.75883022
136hippocampus development (GO:0021766)2.70715770
137neuron migration (GO:0001764)2.70666506
138positive regulation of oligodendrocyte differentiation (GO:0048714)2.68900922
139homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.68318724
140neurofilament cytoskeleton organization (GO:0060052)2.67059147
141negative regulation of axonogenesis (GO:0050771)2.66215904
142dendritic spine organization (GO:0097061)2.65171973
143long-chain fatty acid biosynthetic process (GO:0042759)2.64602172
144nonmotile primary cilium assembly (GO:0035058)2.64266090
145organelle transport along microtubule (GO:0072384)2.56302489
146regulation of penile erection (GO:0060405)2.53778553
147axonogenesis (GO:0007409)2.53523076
148regulation of axon guidance (GO:1902667)2.46532293
149nervous system development (GO:0007399)2.46271620
150retina vasculature morphogenesis in camera-type eye (GO:0061299)2.44730896
151establishment of melanosome localization (GO:0032401)2.43198856
152paraxial mesoderm development (GO:0048339)2.42740430
153spinal cord development (GO:0021510)2.41660299
154regulation of dendritic spine morphogenesis (GO:0061001)2.41439499

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.66051890
2GBX2_23144817_ChIP-Seq_PC3_Human3.61006084
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.16990526
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.10902552
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.05919575
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.81180238
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.81180238
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74327131
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.72633241
10* REST_21632747_ChIP-Seq_MESCs_Mouse2.69394115
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.61943345
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.59123313
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57317742
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.55488564
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.54600978
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.49693783
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.49139539
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.43747827
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.33991246
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.33200383
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.29402939
22* REST_18959480_ChIP-ChIP_MESCs_Mouse2.24651295
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.24244289
24AR_21572438_ChIP-Seq_LNCaP_Human2.19204237
25DROSHA_22980978_ChIP-Seq_HELA_Human2.18392652
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.14196672
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.13249004
28IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09639871
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98095646
30TAF15_26573619_Chip-Seq_HEK293_Human1.96764596
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.96225371
32RARB_27405468_Chip-Seq_BRAIN_Mouse1.94657465
33ZNF274_21170338_ChIP-Seq_K562_Hela1.90097001
34POU5F1_16153702_ChIP-ChIP_HESCs_Human1.79315676
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.77276251
36GATA1_26923725_Chip-Seq_HPCs_Mouse1.75441132
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.68638676
38SMAD4_21799915_ChIP-Seq_A2780_Human1.66060202
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.65193316
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.64729192
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.61840866
42NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.59469137
43MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.59249557
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.58038633
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.56384503
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55493672
47ERG_21242973_ChIP-ChIP_JURKAT_Human1.53042303
48* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50160498
49SOX2_16153702_ChIP-ChIP_HESCs_Human1.49476948
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.47833871
51RING1B_27294783_Chip-Seq_ESCs_Mouse1.45857325
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44853133
53IGF1R_20145208_ChIP-Seq_DFB_Human1.40301653
54BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39320246
55* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35476498
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34419574
57FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.34218551
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34088217
59P300_19829295_ChIP-Seq_ESCs_Human1.33339658
60EWS_26573619_Chip-Seq_HEK293_Human1.32236969
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26189764
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.25732151
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.25350319
64* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24597079
65AR_25329375_ChIP-Seq_VCAP_Human1.24463699
66MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23593324
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23499339
68TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22817876
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.21177224
70* RNF2_27304074_Chip-Seq_NSC_Mouse1.21112691
71* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.20396844
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19791288
73AR_19668381_ChIP-Seq_PC3_Human1.19197818
74STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16951233
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16892213
76LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15973070
77TBX3_20139965_ChIP-Seq_MESCs_Mouse1.15949271
78STAT3_23295773_ChIP-Seq_U87_Human1.15533426
79CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14951850
80TBX3_20139965_ChIP-Seq_ESCs_Mouse1.14080959
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13764185
82EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12818735
83TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12628933
84DNAJC2_21179169_ChIP-ChIP_NT2_Human1.12371383
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.08188806
86TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06644026
87POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06644026
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05530959
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03883017
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03619290
91IRF1_19129219_ChIP-ChIP_H3396_Human1.03301244
92TCF4_23295773_ChIP-Seq_U87_Human1.03271445
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03171464
94* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03009174
95SMAD3_21741376_ChIP-Seq_ESCs_Human1.02898038
96ARNT_22903824_ChIP-Seq_MCF-7_Human1.01573086
97TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99375823
98YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99262998
99RUNX2_22187159_ChIP-Seq_PCA_Human0.98885598
100HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98871180
101ZFP281_18757296_ChIP-ChIP_E14_Mouse0.98408174
102CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.98067289
103TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97994936
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97670023
105POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.96933504
106ER_23166858_ChIP-Seq_MCF-7_Human0.96832274
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.96693129
108ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.95521495
109VDR_22108803_ChIP-Seq_LS180_Human0.94529255
110AHR_22903824_ChIP-Seq_MCF-7_Human0.93963753
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.92209850
112SOX9_26525672_Chip-Seq_HEART_Mouse0.91717659
113TP53_20018659_ChIP-ChIP_R1E_Mouse0.91581168
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90725727
115WT1_19549856_ChIP-ChIP_CCG9911_Human0.90219810
116ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90145917
117RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.89751505
118SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.89672684
119PRDM14_20953172_ChIP-Seq_ESCs_Human0.86830560
120* JUN_21703547_ChIP-Seq_K562_Human0.86402039
121FUS_26573619_Chip-Seq_HEK293_Human0.85225453
122BCAT_22108803_ChIP-Seq_LS180_Human0.84906056
123TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.84856567
124SMAD4_21741376_ChIP-Seq_HESCs_Human0.84668467
125EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.84602766
126KDM2B_26808549_Chip-Seq_K562_Human0.82521544
127* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.82418374
128SMAD_19615063_ChIP-ChIP_OVARY_Human0.81118825
129TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.80571510

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.53163266
2MP0003880_abnormal_central_pattern4.25051108
3MP0003635_abnormal_synaptic_transmissio3.68371038
4MP0005423_abnormal_somatic_nervous3.64159829
5MP0009046_muscle_twitch3.37639043
6MP0004270_analgesia3.24141880
7MP0009745_abnormal_behavioral_response3.07943925
8MP0001968_abnormal_touch/_nociception3.01447700
9MP0002063_abnormal_learning/memory/cond2.87613187
10MP0002064_seizures2.86196209
11MP0003121_genomic_imprinting2.81308651
12MP0002735_abnormal_chemical_nociception2.76522955
13MP0002734_abnormal_mechanical_nocicepti2.75694898
14MP0002272_abnormal_nervous_system2.69418433
15MP0002572_abnormal_emotion/affect_behav2.63638750
16MP0001486_abnormal_startle_reflex2.59644615
17MP0006276_abnormal_autonomic_nervous2.25894286
18MP0002067_abnormal_sensory_capabilities2.24383687
19MP0002184_abnormal_innervation2.23347298
20MP0002736_abnormal_nociception_after2.22461268
21MP0002733_abnormal_thermal_nociception2.20570318
22MP0004858_abnormal_nervous_system2.20347825
23MP0008877_abnormal_DNA_methylation2.10089750
24MP0001970_abnormal_pain_threshold2.06477151
25MP0001440_abnormal_grooming_behavior2.05561183
26MP0008569_lethality_at_weaning1.96383610
27MP0002557_abnormal_social/conspecific_i1.95594780
28MP0000778_abnormal_nervous_system1.93763436
29MP0005187_abnormal_penis_morphology1.87300616
30MP0005646_abnormal_pituitary_gland1.85159923
31MP0003329_amyloid_beta_deposits1.84678160
32MP0004142_abnormal_muscle_tone1.79695328
33MP0001502_abnormal_circadian_rhythm1.78139845
34MP0005645_abnormal_hypothalamus_physiol1.77839971
35MP0002822_catalepsy1.76265858
36MP0003123_paternal_imprinting1.71459248
37MP0004924_abnormal_behavior1.70308840
38MP0005386_behavior/neurological_phenoty1.70308840
39MP0001984_abnormal_olfaction1.68561982
40MP0001501_abnormal_sleep_pattern1.65370288
41MP0000955_abnormal_spinal_cord1.65133389
42MP0004811_abnormal_neuron_physiology1.64033082
43MP0001529_abnormal_vocalization1.62567624
44MP0002882_abnormal_neuron_morphology1.56670993
45MP0004885_abnormal_endolymph1.51566508
46MP0002102_abnormal_ear_morphology1.50666894
47MP0004742_abnormal_vestibular_system1.45238075
48MP0002066_abnormal_motor_capabilities/c1.44461212
49MP0009780_abnormal_chondrocyte_physiolo1.42836861
50MP0003122_maternal_imprinting1.42137285
51MP0005551_abnormal_eye_electrophysiolog1.42081997
52MP0006072_abnormal_retinal_apoptosis1.28485690
53MP0002751_abnormal_autonomic_nervous1.26459183
54MP0002229_neurodegeneration1.25250572
55MP0003690_abnormal_glial_cell1.25067584
56MP0001299_abnormal_eye_distance/1.20560033
57MP0003634_abnormal_glial_cell1.18900398
58MP0002152_abnormal_brain_morphology1.18850761
59MP0003011_delayed_dark_adaptation1.17974187
60MP0002909_abnormal_adrenal_gland1.16610048
61MP0003633_abnormal_nervous_system1.14689094
62MP0008789_abnormal_olfactory_epithelium1.14404388
63MP0002089_abnormal_postnatal_growth/wei1.14361701
64MP0000751_myopathy1.11603120
65MP0005171_absent_coat_pigmentation1.09126822
66MP0003567_abnormal_fetal_cardiomyocyte1.08017392
67MP0003787_abnormal_imprinting1.07591944
68MP0002752_abnormal_somatic_nervous1.06705643
69MP0003631_nervous_system_phenotype1.01607026
70MP0001963_abnormal_hearing_physiology1.01439322
71MP0002638_abnormal_pupillary_reflex1.00731090
72MP0004145_abnormal_muscle_electrophysio1.00607454
73MP0000647_abnormal_sebaceous_gland0.99359903
74MP0002653_abnormal_ependyma_morphology0.98972007
75MP0000920_abnormal_myelination0.95768746
76MP0003172_abnormal_lysosome_physiology0.95165004
77MP0003119_abnormal_digestive_system0.95109222
78MP0005253_abnormal_eye_physiology0.94115060
79MP0003879_abnormal_hair_cell0.94013864
80MP0001905_abnormal_dopamine_level0.93562753
81MP0002081_perinatal_lethality0.90912957
82MP0000631_abnormal_neuroendocrine_gland0.90005483
83MP0005499_abnormal_olfactory_system0.89706276
84MP0005394_taste/olfaction_phenotype0.89706276
85MP0002090_abnormal_vision0.89641414
86MP0003137_abnormal_impulse_conducting0.89408873
87MP0003136_yellow_coat_color0.88862509
88MP0002069_abnormal_eating/drinking_beha0.88420711
89MP0001188_hyperpigmentation0.87771078
90MP0003632_abnormal_nervous_system0.87416521
91MP0004133_heterotaxia0.87402708
92MP0000049_abnormal_middle_ear0.86906484
93MP0002233_abnormal_nose_morphology0.86188605
94MP0001177_atelectasis0.84748359
95MP0003937_abnormal_limbs/digits/tail_de0.82983658
96MP0000604_amyloidosis0.81573969
97MP0004085_abnormal_heartbeat0.81183588
98MP0008770_decreased_survivor_rate0.80853985
99MP0002697_abnormal_eye_size0.80845127
100MP0003315_abnormal_perineum_morphology0.80768841
101MP0003183_abnormal_peptide_metabolism0.80395708
102MP0008995_early_reproductive_senescence0.79762599
103MP0001986_abnormal_taste_sensitivity0.78865742
104MP0003890_abnormal_embryonic-extraembry0.78116527
105MP0001293_anophthalmia0.77292971
106MP0005391_vision/eye_phenotype0.77118271
107MP0000534_abnormal_ureter_morphology0.73349505
108MP0010386_abnormal_urinary_bladder0.73171875
109MP0010768_mortality/aging0.72716253
110MP0003221_abnormal_cardiomyocyte_apopto0.72655896
111MP0005623_abnormal_meninges_morphology0.70708946
112MP0000026_abnormal_inner_ear0.70087703
113MP0005410_abnormal_fertilization0.69739853
114MP0005195_abnormal_posterior_eye0.69656215
115MP0004043_abnormal_pH_regulation0.69405981
116MP0004215_abnormal_myocardial_fiber0.69320917
117MP0001943_abnormal_respiration0.68209876
118MP0003861_abnormal_nervous_system0.66799181
119MP0001485_abnormal_pinna_reflex0.66176571
120MP0008872_abnormal_physiological_respon0.65549616
121MP0004233_abnormal_muscle_weight0.62973918
122MP0002837_dystrophic_cardiac_calcinosis0.61732069
123MP0005535_abnormal_body_temperature0.60272418
124MP0002108_abnormal_muscle_morphology0.58894693
125MP0003646_muscle_fatigue0.58520526
126MP0010770_preweaning_lethality0.57960743
127MP0002082_postnatal_lethality0.57960743
128MP0009384_cardiac_valve_regurgitation0.57862098
129MP0010769_abnormal_survival0.57171289

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.27467425
2Focal motor seizures (HP:0011153)6.02544804
3Progressive cerebellar ataxia (HP:0002073)4.87384592
4Focal seizures (HP:0007359)4.86839524
5Action tremor (HP:0002345)4.73061946
6Visual hallucinations (HP:0002367)4.59580704
7Febrile seizures (HP:0002373)4.13841461
8Atonic seizures (HP:0010819)3.98359212
9Epileptic encephalopathy (HP:0200134)3.89813915
10Pheochromocytoma (HP:0002666)3.54593284
11Absence seizures (HP:0002121)3.48103137
12Cortical dysplasia (HP:0002539)3.42199521
13Dialeptic seizures (HP:0011146)3.33721436
14Dysdiadochokinesis (HP:0002075)3.31853945
15Supranuclear gaze palsy (HP:0000605)3.29065845
16Generalized tonic-clonic seizures (HP:0002069)3.10998070
17Neuroendocrine neoplasm (HP:0100634)3.05400826
18Broad-based gait (HP:0002136)3.01968789
19Ankle clonus (HP:0011448)2.98433894
20Abnormal eating behavior (HP:0100738)2.95627792
21Synostosis involving the elbow (HP:0003938)2.92978361
22Humeroradial synostosis (HP:0003041)2.92978361
23Gaze-evoked nystagmus (HP:0000640)2.92938821
24Aplasia/Hypoplasia of the sternum (HP:0006714)2.92431852
25Truncal ataxia (HP:0002078)2.89674205
26Depression (HP:0000716)2.87525887
27Abnormal hair whorl (HP:0010721)2.86987891
28Lissencephaly (HP:0001339)2.79791922
29Hyperventilation (HP:0002883)2.76639671
30Diplopia (HP:0000651)2.76637943
31Abnormality of binocular vision (HP:0011514)2.76637943
32Polyphagia (HP:0002591)2.75596349
33Scanning speech (HP:0002168)2.74967790
34Impaired vibration sensation in the lower limbs (HP:0002166)2.72108610
35Hemiparesis (HP:0001269)2.70987282
36Dysmetria (HP:0001310)2.66491444
37Mutism (HP:0002300)2.65352305
38Anxiety (HP:0000739)2.63725849
39Hyperglycinemia (HP:0002154)2.60544301
40Megalencephaly (HP:0001355)2.60183342
41Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.59129815
42Peripheral hypomyelination (HP:0007182)2.58642635
43Hypoglycemic seizures (HP:0002173)2.58530380
44Genetic anticipation (HP:0003743)2.56340904
45Drooling (HP:0002307)2.52856669
46Excessive salivation (HP:0003781)2.52856669
47Neoplasm of the peripheral nervous system (HP:0100007)2.50496367
48Atrophy/Degeneration involving motor neurons (HP:0007373)2.47512706
49Abnormal social behavior (HP:0012433)2.47130490
50Impaired social interactions (HP:0000735)2.47130490
51Limb dystonia (HP:0002451)2.46922401
52Agitation (HP:0000713)2.46816991
53Abnormality of the labia minora (HP:0012880)2.45180605
54Intestinal atresia (HP:0011100)2.44817231
55Poor eye contact (HP:0000817)2.43481605
56Postural instability (HP:0002172)2.43426792
57Intention tremor (HP:0002080)2.41146626
58Urinary bladder sphincter dysfunction (HP:0002839)2.40790231
59Hemiplegia (HP:0002301)2.40149697
60Progressive inability to walk (HP:0002505)2.39596450
61Urinary urgency (HP:0000012)2.38044881
62Wrist flexion contracture (HP:0001239)2.36609086
63Abnormality of the corticospinal tract (HP:0002492)2.33373819
64Spastic gait (HP:0002064)2.31945710
65Anosmia (HP:0000458)2.30850942
66Abnormality of the anterior horn cell (HP:0006802)2.30694403
67Degeneration of anterior horn cells (HP:0002398)2.30694403
68Insomnia (HP:0100785)2.30009740
69Neurofibrillary tangles (HP:0002185)2.23394810
70Narrow nasal bridge (HP:0000446)2.19000585
71Failure to thrive in infancy (HP:0001531)2.18823264
72Cerebellar dysplasia (HP:0007033)2.18229618
73Termporal pattern (HP:0011008)2.16404502
74Insidious onset (HP:0003587)2.16404502
75Polymicrogyria (HP:0002126)2.15883698
76Nephrogenic diabetes insipidus (HP:0009806)2.15176235
77Hypoplasia of the corpus callosum (HP:0002079)2.14678600
78Uterine leiomyosarcoma (HP:0002891)2.13532784
79Leiomyosarcoma (HP:0100243)2.13532784
80Abnormality of the diencephalon (HP:0010662)2.12956125
81Muscular hypotonia of the trunk (HP:0008936)2.12692673
82Aplasia involving bones of the upper limbs (HP:0009823)2.12110750
83Aplasia of the phalanges of the hand (HP:0009802)2.12110750
84Aplasia involving bones of the extremities (HP:0009825)2.12110750
85Obstructive sleep apnea (HP:0002870)2.10296442
86Status epilepticus (HP:0002133)2.10051579
87Amyotrophic lateral sclerosis (HP:0007354)2.07957793
88Aplasia/Hypoplasia of the brainstem (HP:0007362)2.07511166
89Hypoplasia of the brainstem (HP:0002365)2.07511166
90Congenital primary aphakia (HP:0007707)2.07481383
91Pachygyria (HP:0001302)2.07405286
92Vaginal atresia (HP:0000148)2.06758573
93Abnormality of ocular smooth pursuit (HP:0000617)2.06755100
94Gait imbalance (HP:0002141)2.06483584
95Amblyopia (HP:0000646)2.05922439
96Postural tremor (HP:0002174)2.05390408
97Impaired smooth pursuit (HP:0007772)2.03346340
98Increased nuchal translucency (HP:0010880)2.03121869
99Sleep apnea (HP:0010535)2.02935167
100Bradykinesia (HP:0002067)2.00369101
101Esotropia (HP:0000565)2.00207646
102Abnormality of the hip-girdle musculature (HP:0001445)1.99886253
103Abnormality of the musculature of the pelvis (HP:0001469)1.99886253
104Generalized hypotonia (HP:0001290)1.99070487
105Spastic tetraplegia (HP:0002510)1.98271638
106Specific learning disability (HP:0001328)1.98233649
107Blue irides (HP:0000635)1.96897201
108Genital tract atresia (HP:0001827)1.96607718
109Ulnar claw (HP:0001178)1.95363581
110Postnatal microcephaly (HP:0005484)1.94882327
111Cerebral inclusion bodies (HP:0100314)1.94729952
112Abnormal lung lobation (HP:0002101)1.94659092
113Absent speech (HP:0001344)1.94287701
114Labial hypoplasia (HP:0000066)1.92844528
115Lower limb muscle weakness (HP:0007340)1.92645086
116Poor suck (HP:0002033)1.92327412
117Spinal canal stenosis (HP:0003416)1.91842445
118Hypoventilation (HP:0002791)1.91792405
119Poor head control (HP:0002421)1.90742922
120Hammertoe (HP:0001765)1.90713713
121Aqueductal stenosis (HP:0002410)1.89507500
122EEG with generalized epileptiform discharges (HP:0011198)1.89310383
123Oligodactyly (hands) (HP:0001180)1.89281537
124Overriding aorta (HP:0002623)1.88478766
125Renal hypoplasia (HP:0000089)1.88426711
126Medial flaring of the eyebrow (HP:0010747)1.88139921
127Torticollis (HP:0000473)1.87764860
128Gait ataxia (HP:0002066)1.87240087
129Abnormality of saccadic eye movements (HP:0000570)1.86327465
130Epileptiform EEG discharges (HP:0011182)1.86204649
131Hypoglycemic coma (HP:0001325)1.85987032
132Transitional cell carcinoma of the bladder (HP:0006740)1.85496155
133Abnormality of the lower motor neuron (HP:0002366)1.85280356
134Hypsarrhythmia (HP:0002521)1.85260352
135Bladder neoplasm (HP:0009725)1.83573651
136Bladder carcinoma (HP:0002862)1.83573651
137Split foot (HP:0001839)1.82922840
138Scrotal hypoplasia (HP:0000046)1.82455241
139Retinal dysplasia (HP:0007973)1.82246860
140Psychosis (HP:0000709)1.79734120
141Dysmetric saccades (HP:0000641)1.79552928
142Neuronal loss in central nervous system (HP:0002529)1.78466553
143Ventricular fibrillation (HP:0001663)1.78118284
144Exotropia (HP:0000577)1.75339817
145Shoulder girdle muscle weakness (HP:0003547)1.74560235
146Abnormality of the parathyroid morphology (HP:0011766)1.74377990
147Fetal akinesia sequence (HP:0001989)1.74150241
148Hypoplastic female external genitalia (HP:0012815)1.73927879
149Abnormality of the metopic suture (HP:0005556)1.73799056
150Abnormal neuron morphology (HP:0012757)1.71902779
151Abnormality of the motor neurons (HP:0002450)1.71902779
152Tubulointerstitial nephritis (HP:0001970)1.70994791
153Micropenis (HP:0000054)1.70004714
154Occipital encephalocele (HP:0002085)1.69472717
155Elfin facies (HP:0004428)1.69316672
156Chronic hepatic failure (HP:0100626)1.69041327

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA35.89176825
2NTRK35.18309175
3CASK3.86922080
4TRIM283.73522772
5MARK13.43776163
6TNIK3.09491843
7NTRK22.88227576
8MAP3K42.79548441
9MINK12.73147723
10MAP3K92.55005934
11PHKG12.46802048
12PHKG22.46802048
13MAP2K72.37673304
14MAPK131.93825638
15MAP3K121.90643855
16LMTK21.88380886
17EPHA41.88309005
18CSNK1G31.79732689
19MAP2K41.77355454
20PAK61.75325718
21BMPR1B1.71798985
22PBK1.71241120
23CSNK1A1L1.57910251
24PRKCG1.50671536
25CSNK1G11.49594371
26MAP3K61.48042645
27UHMK11.47132292
28SRPK11.42998415
29GRK51.42539842
30ICK1.42322860
31PNCK1.42072673
32CDK51.35505513
33NTRK11.33503106
34EPHB21.31036672
35SGK2231.30277752
36SGK4941.30277752
37MAP4K21.29096660
38DAPK21.26730366
39DYRK31.26250665
40TYRO31.25920468
41CAMKK11.25753771
42CCNB11.23390664
43CDK191.22783968
44SIK21.19163292
45CAMKK21.18036877
46SGK21.14537079
47PRKD31.10512097
48PLK21.10142573
49PRPF4B1.06608134
50CAMK2A1.01944050
51BCKDK0.99364771
52MKNK20.98057522
53RPS6KA40.93972136
54SGK30.87198725
55LATS20.86926285
56CDK140.81219539
57WNK30.80684264
58KSR10.80484937
59CDK180.80121645
60EPHB10.79350080
61CDK150.79231220
62PRKCH0.78312162
63CAMK1G0.77126195
64PAK30.77056646
65STK380.76501005
66FES0.76430100
67KSR20.76263245
68DYRK1A0.75624717
69RET0.75066482
70LIMK10.73677190
71WNK10.73134140
72TTK0.72541873
73CAMK10.71271581
74SIK30.69426315
75CAMK2G0.69175253
76MUSK0.68555302
77CDK11A0.68151520
78CAMK2B0.66877781
79CSNK1G20.66726188
80PLK10.66590636
81ADRBK10.65376731
82RIPK10.63837553
83OXSR10.63002470
84ARAF0.61959906
85DYRK20.61409247
86SCYL20.61407522
87PRKCE0.60103749
88RIPK40.59088540
89ROCK20.58432783
90STK110.58411330
91ERBB30.58230388
92PRKCZ0.58149652
93DAPK10.57793822
94ERBB40.57299851
95CAMK40.56099955
96ERBB20.55954505
97PINK10.55874631
98CAMK2D0.53828132
99SGK10.53621140
100DYRK1B0.52958573
101RPS6KA50.52304626
102GRK70.52171828
103ALK0.51761669
104ROCK10.51405334
105MET0.50281850
106BCR0.49700173
107AURKA0.49589758
108FGFR20.49199329
109INSRR0.49173549
110RPS6KA30.47735685
111CDK80.45537861
112FER0.43371514
113MAPKAPK50.43115091
114RPS6KB10.42990051
115PRKACA0.41493746
116CDC42BPA0.41332598
117PRKCB0.40052619
118CSNK1D0.39788815
119PKN10.39447699
120MAPK100.39446211
121RPS6KA20.39071336
122PDK10.38752429
123PRKACG0.38624125
124PRKACB0.38249022
125PDPK10.37762912
126EGFR0.37135453
127MARK20.36972679
128TSSK60.36832284
129PDGFRA0.36489417
130MAP3K20.35407766
131PRKAA10.32572562
132MAPK90.29313852
133CDK10.28687525
134GSK3B0.27776622
135CSNK1A10.26406791
136CSNK1E0.24603158
137FYN0.23902141
138PRKDC0.23535240
139NEK60.21116449
140BRD40.20420165
141MAP3K50.19562879
142SRC0.19097142
143MKNK10.18780016
144EIF2AK30.18466772
145CLK10.16995512

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.73787998
2Nicotine addiction_Homo sapiens_hsa050333.94933033
3Synaptic vesicle cycle_Homo sapiens_hsa047213.32953545
4GABAergic synapse_Homo sapiens_hsa047272.90441618
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.71252645
6Glutamatergic synapse_Homo sapiens_hsa047242.53862989
7Circadian entrainment_Homo sapiens_hsa047132.43904313
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.41392959
9Morphine addiction_Homo sapiens_hsa050322.36305950
10Olfactory transduction_Homo sapiens_hsa047402.36226854
11Long-term potentiation_Homo sapiens_hsa047202.21547240
12Amphetamine addiction_Homo sapiens_hsa050312.09104395
13Dopaminergic synapse_Homo sapiens_hsa047282.04790036
14Taste transduction_Homo sapiens_hsa047422.00128967
15Steroid biosynthesis_Homo sapiens_hsa001001.96472719
16Salivary secretion_Homo sapiens_hsa049701.89943956
17Insulin secretion_Homo sapiens_hsa049111.88345746
18Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.82923872
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.81960483
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.81302737
21Gastric acid secretion_Homo sapiens_hsa049711.81277072
22Cholinergic synapse_Homo sapiens_hsa047251.80478182
23Long-term depression_Homo sapiens_hsa047301.75302518
24Fatty acid elongation_Homo sapiens_hsa000621.74878567
25Collecting duct acid secretion_Homo sapiens_hsa049661.61135504
26Serotonergic synapse_Homo sapiens_hsa047261.58685012
27Cocaine addiction_Homo sapiens_hsa050301.58664464
28* Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56292050
29Phototransduction_Homo sapiens_hsa047441.54794433
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.54627462
31Calcium signaling pathway_Homo sapiens_hsa040201.41521731
32Renin secretion_Homo sapiens_hsa049241.40386348
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.38601533
34Gap junction_Homo sapiens_hsa045401.35802617
35Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29354313
36* Cardiac muscle contraction_Homo sapiens_hsa042601.28792898
37* Oxytocin signaling pathway_Homo sapiens_hsa049211.23734976
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22060041
39GnRH signaling pathway_Homo sapiens_hsa049121.21762784
40Axon guidance_Homo sapiens_hsa043601.20790219
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.19352135
42Vibrio cholerae infection_Homo sapiens_hsa051101.15477138
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.13600922
44Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.12744981
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.12481596
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.10689958
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08181152
48Type II diabetes mellitus_Homo sapiens_hsa049301.04850220
49cAMP signaling pathway_Homo sapiens_hsa040241.04222967
50Estrogen signaling pathway_Homo sapiens_hsa049151.00303425
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99040146
52Colorectal cancer_Homo sapiens_hsa052100.93626290
53Glioma_Homo sapiens_hsa052140.93203559
54ErbB signaling pathway_Homo sapiens_hsa040120.92488748
55Propanoate metabolism_Homo sapiens_hsa006400.91382924
56Oxidative phosphorylation_Homo sapiens_hsa001900.91165706
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89926021
58Melanogenesis_Homo sapiens_hsa049160.89120055
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88566996
60Nitrogen metabolism_Homo sapiens_hsa009100.87100560
61Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.86319219
62Oocyte meiosis_Homo sapiens_hsa041140.82403758
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81494432
64Biosynthesis of amino acids_Homo sapiens_hsa012300.81266094
65Regulation of autophagy_Homo sapiens_hsa041400.80973780
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80394399
67Hippo signaling pathway_Homo sapiens_hsa043900.80086632
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.78824095
69Thyroid hormone synthesis_Homo sapiens_hsa049180.78620311
70Fanconi anemia pathway_Homo sapiens_hsa034600.78292037
71Pancreatic secretion_Homo sapiens_hsa049720.78094206
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77821399
73cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76759385
74Alzheimers disease_Homo sapiens_hsa050100.76673975
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.75660727
76Carbon metabolism_Homo sapiens_hsa012000.74065142
77Selenocompound metabolism_Homo sapiens_hsa004500.70760444
78Dorso-ventral axis formation_Homo sapiens_hsa043200.70507344
79Butanoate metabolism_Homo sapiens_hsa006500.70399539
80Bile secretion_Homo sapiens_hsa049760.70184472
81Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69714491
82Parkinsons disease_Homo sapiens_hsa050120.69640064
83* Dilated cardiomyopathy_Homo sapiens_hsa054140.69235760
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69185301
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.65606164
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65328156
87Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65196793
88Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63179091
89Fatty acid biosynthesis_Homo sapiens_hsa000610.62722629
90Mismatch repair_Homo sapiens_hsa034300.60445827
91Notch signaling pathway_Homo sapiens_hsa043300.60133204
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58392855
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57419387
94* MAPK signaling pathway_Homo sapiens_hsa040100.57200239
95Glucagon signaling pathway_Homo sapiens_hsa049220.56102337
96Endometrial cancer_Homo sapiens_hsa052130.56061626
97Base excision repair_Homo sapiens_hsa034100.55682559
98Protein export_Homo sapiens_hsa030600.55653816
99Choline metabolism in cancer_Homo sapiens_hsa052310.55074315
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.54847228
101Fatty acid metabolism_Homo sapiens_hsa012120.53235780
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52773824
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52215866
104Prolactin signaling pathway_Homo sapiens_hsa049170.51971725
105Adherens junction_Homo sapiens_hsa045200.51394573
106Alcoholism_Homo sapiens_hsa050340.50584314
107Primary bile acid biosynthesis_Homo sapiens_hsa001200.50038047
108Huntingtons disease_Homo sapiens_hsa050160.49135871
109Insulin signaling pathway_Homo sapiens_hsa049100.48408507
110Tight junction_Homo sapiens_hsa045300.48358844
111DNA replication_Homo sapiens_hsa030300.48185622
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48121094
113Homologous recombination_Homo sapiens_hsa034400.47596740
114mRNA surveillance pathway_Homo sapiens_hsa030150.46636145
115* Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45990082
116Hedgehog signaling pathway_Homo sapiens_hsa043400.45708068
117Ras signaling pathway_Homo sapiens_hsa040140.45639597
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.45454043
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.45075325
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45037928
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.43509745
122Ovarian steroidogenesis_Homo sapiens_hsa049130.42204625
123mTOR signaling pathway_Homo sapiens_hsa041500.42088632
124Type I diabetes mellitus_Homo sapiens_hsa049400.41708429
125Lysine degradation_Homo sapiens_hsa003100.41672524
126Galactose metabolism_Homo sapiens_hsa000520.41443203
127Prion diseases_Homo sapiens_hsa050200.40877677
128Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40726411
129Rap1 signaling pathway_Homo sapiens_hsa040150.39050990
130Renal cell carcinoma_Homo sapiens_hsa052110.38748140
131Circadian rhythm_Homo sapiens_hsa047100.38658290
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36924158
133Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.36198102
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.35702002
135Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.35625355
136Wnt signaling pathway_Homo sapiens_hsa043100.35063898
137Basal transcription factors_Homo sapiens_hsa030220.34710987
138Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33083283
139AMPK signaling pathway_Homo sapiens_hsa041520.32218346
140Endocytosis_Homo sapiens_hsa041440.31862672
141Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31484370
142Phagosome_Homo sapiens_hsa041450.31372375
143Inositol phosphate metabolism_Homo sapiens_hsa005620.28985927

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