C5ORF67

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein prenylation (GO:0018342)8.88132006
2prenylation (GO:0097354)8.88132006
3mitochondrion transport along microtubule (GO:0047497)8.21710384
4establishment of mitochondrion localization, microtubule-mediated (GO:0034643)8.21710384
5macroautophagy (GO:0016236)7.21065979
6establishment of mitochondrion localization (GO:0051654)7.15573119
7cytokinetic process (GO:0032506)6.53264827
8pyrimidine-containing compound transmembrane transport (GO:0072531)6.50465835
9L-methionine biosynthetic process from methylthioadenosine (GO:0019509)6.39513120
10regulation of translation in response to stress (GO:0043555)6.13609758
11seminiferous tubule development (GO:0072520)5.99700313
12Golgi to endosome transport (GO:0006895)5.62455819
13branched-chain amino acid catabolic process (GO:0009083)5.47586071
14L-methionine salvage (GO:0071267)5.20764727
15L-methionine biosynthetic process (GO:0071265)5.20764727
16amino acid salvage (GO:0043102)5.20764727
17membrane budding (GO:0006900)5.15566418
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.11435848
19cardiovascular system development (GO:0072358)4.98142861
20nucleotide transmembrane transport (GO:1901679)4.96415878
21regulation of podosome assembly (GO:0071801)4.79289356
22radial glial cell differentiation (GO:0060019)4.62938430
23regulation of fever generation (GO:0031620)4.58207659
24regulation of penile erection (GO:0060405)4.55157980
25N-terminal protein amino acid acetylation (GO:0006474)4.49119532
26heterotypic cell-cell adhesion (GO:0034113)4.48489524
27regulation of cGMP metabolic process (GO:0030823)4.40985149
28branched-chain amino acid metabolic process (GO:0009081)4.40398816
29sulfur amino acid catabolic process (GO:0000098)4.39713821
30regulation of triglyceride catabolic process (GO:0010896)4.34589809
31positive regulation of heat generation (GO:0031652)4.16964839
32cardiolipin metabolic process (GO:0032048)4.16621152
33negative regulation of phagocytosis (GO:0050765)3.99037637
34RNA destabilization (GO:0050779)3.94190918
35stress fiber assembly (GO:0043149)3.88717435
36positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.85329062
37regulation of interleukin-12 biosynthetic process (GO:0045075)3.77786133
38regulation of germinal center formation (GO:0002634)3.68887506
39single strand break repair (GO:0000012)3.66169354
40positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.64122560
41regulation of heat generation (GO:0031650)3.64007563
42GTP biosynthetic process (GO:0006183)3.56610926
43RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.52997032
44tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.52997032
45phospholipid efflux (GO:0033700)3.51270533
46positive regulation of interleukin-8 secretion (GO:2000484)3.48505939
47negative regulation of interleukin-1 beta production (GO:0032691)3.46384037
48potassium ion export (GO:0071435)3.42241652
49negative regulation of mast cell activation (GO:0033004)3.37512097
50methionine biosynthetic process (GO:0009086)3.36971897
51positive regulation by symbiont of host defense response (GO:0052509)3.32755031
52modulation by symbiont of host defense response (GO:0052031)3.32755031
53modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.32755031
54modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.32755031
55positive regulation by organism of defense response of other organism involved in symbiotic interact3.32755031
56modulation by symbiont of host immune response (GO:0052553)3.32755031
57adaptation of signaling pathway (GO:0023058)3.24075822
58regulation of protein kinase A signaling (GO:0010738)3.20318208
59phosphatidylglycerol biosynthetic process (GO:0006655)3.18957988
60spindle assembly involved in mitosis (GO:0090307)3.17975229
61neuronal action potential propagation (GO:0019227)3.16944783
62regulation of acute inflammatory response to antigenic stimulus (GO:0002864)3.14804465
63negative regulation of lipid catabolic process (GO:0050995)3.08428860
64negative regulation of interleukin-12 production (GO:0032695)3.06125793
65centrosome duplication (GO:0051298)3.05615410
66oligodendrocyte development (GO:0014003)3.04601127
67UTP biosynthetic process (GO:0006228)3.04548099
68positive regulation of cytokinesis (GO:0032467)3.02820367
69negative regulation of nitric-oxide synthase activity (GO:0051001)3.02664842
70microtubule nucleation (GO:0007020)3.02542943
71negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.01273015
72negative regulation of cell killing (GO:0031342)3.01273015
73pre-miRNA processing (GO:0031054)3.00552822
74cellular response to ketone (GO:1901655)3.00132813
75phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.99662783
76meiotic chromosome segregation (GO:0045132)2.99431680
77DNA ligation (GO:0006266)2.98785171
78negative regulation of translational initiation (GO:0045947)2.93985032
79lipoprotein transport (GO:0042953)2.93060665
80cellular modified amino acid catabolic process (GO:0042219)2.91946720
81negative regulation of interleukin-1 production (GO:0032692)2.90345516
82nucleotide transport (GO:0006862)2.89540989
83negative regulation of sodium ion transport (GO:0010766)2.86278531
84negative regulation of catecholamine secretion (GO:0033604)2.85328902
85fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.84940792
86retina vasculature morphogenesis in camera-type eye (GO:0061299)2.83562081
87Notch receptor processing (GO:0007220)2.82381486
88cellular response to interleukin-15 (GO:0071350)2.79569454
89methionine metabolic process (GO:0006555)2.75925959
90regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.74403234
91ribosomal large subunit biogenesis (GO:0042273)2.74278979
92negative regulation of membrane potential (GO:0045837)2.73939326
93nucleoside diphosphate phosphorylation (GO:0006165)2.73732919
94regulation of interferon-gamma biosynthetic process (GO:0045072)2.71891221
95plasma lipoprotein particle assembly (GO:0034377)2.70180920
96mitotic cytokinesis (GO:0000281)2.68096255
97microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.67903714
98progesterone metabolic process (GO:0042448)2.67762350
99valine metabolic process (GO:0006573)11.5135168
100signal peptide processing (GO:0006465)10.1091862

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse9.86360731
2ELF1_17652178_ChIP-ChIP_JURKAT_Human6.79235824
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse5.31824193
4AR_21572438_ChIP-Seq_LNCaP_Human4.28329758
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.57529426
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.99623059
7EZH2_22144423_ChIP-Seq_EOC_Human2.79746032
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.64876241
9ZNF274_21170338_ChIP-Seq_K562_Hela2.60172220
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.60058513
11VDR_22108803_ChIP-Seq_LS180_Human2.45304347
12RUNX_20019798_ChIP-Seq_JUKART_Human2.40959851
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.36229565
14E2F7_22180533_ChIP-Seq_HELA_Human2.22116124
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.05386934
16IRF8_22096565_ChIP-ChIP_GC-B_Human1.95989972
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.86138196
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.80387176
19ER_23166858_ChIP-Seq_MCF-7_Human1.72088864
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.57651216
21CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.54761945
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52648874
23ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.49684863
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.34525083
25PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.32609657
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.31197391
27AR_21909140_ChIP-Seq_LNCAP_Human1.29782871
28PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.24707028
29MYB_26560356_Chip-Seq_TH2_Human1.22680262
30FOXH1_21741376_ChIP-Seq_EPCs_Human1.22402799
31NANOG_19829295_ChIP-Seq_ESCs_Human1.22238766
32SOX2_19829295_ChIP-Seq_ESCs_Human1.22238766
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.21382039
34PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.19765315
35RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.17743604
36FOXA1_21572438_ChIP-Seq_LNCaP_Human1.17080065
37FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16826055
38FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.16019774
39DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15872292
40SMAD4_21799915_ChIP-Seq_A2780_Human1.13016631
41EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.12926960
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10740714
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09547364
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08182864
45SPI1_23547873_ChIP-Seq_NB4_Human1.08063518
46SMRT_27268052_Chip-Seq_Bcells_Human1.07921026
47TCF4_22108803_ChIP-Seq_LS180_Human1.06972153
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05960001
49SALL4_22934838_ChIP-ChIP_CD34+_Human1.05802455
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.05508957
51CREB1_15753290_ChIP-ChIP_HEK293T_Human1.04792414
52SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02326101
53GABP_17652178_ChIP-ChIP_JURKAT_Human1.01310894
54FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.99495500
55POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94697454
56STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.93475720
57GATA3_27048872_Chip-Seq_THYMUS_Human0.93262425
58PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93094442
59FOXH1_21741376_ChIP-Seq_ESCs_Human0.92460050
60MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92218560
61KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.91743120
62GBX2_23144817_ChIP-Seq_PC3_Human0.89261704
63IRF8_27001747_Chip-Seq_BMDM_Mouse0.89010403
64AUTS2_25519132_ChIP-Seq_293T-REX_Human0.88482915
65STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.86106750
66STAT4_19710469_ChIP-ChIP_TH1__Mouse0.84094990
67FOXA1_25329375_ChIP-Seq_VCAP_Human0.83197857
68FOXA1_27270436_Chip-Seq_PROSTATE_Human0.83197857
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83009135
70SUZ12_27294783_Chip-Seq_ESCs_Mouse0.82713608
71IRF8_21731497_ChIP-ChIP_J774_Mouse0.81516409
72SALL1_21062744_ChIP-ChIP_HESCs_Human0.81330279
73NANOG_20526341_ChIP-Seq_ESCs_Human0.81102112
74JARID2_20064375_ChIP-Seq_MESCs_Mouse0.80740014
75GATA3_21878914_ChIP-Seq_MCF-7_Human0.79070904
76PPARA_22158963_ChIP-Seq_LIVER_Mouse0.78917957
77SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.78608560
78TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78380956
79GATA3_26560356_Chip-Seq_TH2_Human0.76567503
80BCAT_22108803_ChIP-Seq_LS180_Human0.76513991
81RUNX2_22187159_ChIP-Seq_PCA_Human0.76329961
82ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.75794257
83NR3C1_23031785_ChIP-Seq_PC12_Mouse0.75330282
84SUZ12_27294783_Chip-Seq_NPCs_Mouse0.75311345
85VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.74211525
86NFE2_27457419_Chip-Seq_LIVER_Mouse0.74098590
87LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.74052445
88GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.73080310
89NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.70951263
90TDRD3_21172665_ChIP-Seq_MCF-7_Human0.70947072
91SOX2_21211035_ChIP-Seq_LN229_Human0.70854111
92PRDM14_20953172_ChIP-Seq_ESCs_Human0.70825208
93CDX2_22108803_ChIP-Seq_LS180_Human0.70474555
94MYB_26560356_Chip-Seq_TH1_Human0.70462072
95CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69947470
96CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.69854574
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.69728816
98ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.69438338
99CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.68354776
100MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.68032872

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.60142278
2MP0002822_catalepsy7.11355524
3MP0001545_abnormal_hematopoietic_system5.04534114
4MP0005397_hematopoietic_system_phenotyp5.04534114
5MP0003646_muscle_fatigue4.64586986
6MP0002653_abnormal_ependyma_morphology3.68608963
7MP0009840_abnormal_foam_cell3.57147175
8MP0004858_abnormal_nervous_system3.19196237
9MP0003303_peritoneal_inflammation2.84880990
10MP0002736_abnormal_nociception_after2.53564327
11MP0004185_abnormal_adipocyte_glucose2.27819433
12MP0001986_abnormal_taste_sensitivity2.15519084
13MP0004883_abnormal_blood_vessel2.10398425
14MP0004145_abnormal_muscle_electrophysio2.07472016
15MP0002638_abnormal_pupillary_reflex1.96602307
16MP0003724_increased_susceptibility_to1.92753957
17MP0002735_abnormal_chemical_nociception1.91719010
18MP0000569_abnormal_digit_pigmentation1.89898131
19MP0000534_abnormal_ureter_morphology1.78835265
20MP0005171_absent_coat_pigmentation1.78718755
21MP0008058_abnormal_DNA_repair1.70856986
22MP0005671_abnormal_response_to1.61523554
23MP0004264_abnormal_extraembryonic_tissu1.61340626
24MP0001968_abnormal_touch/_nociception1.60074814
25MP0003828_pulmonary_edema1.33767139
26MP0005670_abnormal_white_adipose1.32993409
27MP0005360_urolithiasis1.31850968
28MP0005085_abnormal_gallbladder_physiolo1.30516756
29MP0001663_abnormal_digestive_system1.26020563
30MP0003011_delayed_dark_adaptation1.21636296
31MP0005164_abnormal_response_to1.21452968
32MP0003436_decreased_susceptibility_to1.18741291
33MP0001790_abnormal_immune_system1.17208095
34MP0005387_immune_system_phenotype1.17208095
35MP0003718_maternal_effect1.12741569
36MP0005551_abnormal_eye_electrophysiolog1.09160299
37MP0002095_abnormal_skin_pigmentation1.09094259
38MP0009278_abnormal_bone_marrow1.08288055
39MP0010329_abnormal_lipoprotein_level1.05634742
40MP0008569_lethality_at_weaning1.05167083
41MP0002419_abnormal_innate_immunity1.03626668
42MP0001800_abnormal_humoral_immune0.97943740
43MP0002102_abnormal_ear_morphology0.91233230
44MP0002132_abnormal_respiratory_system0.91007763
45MP0002723_abnormal_immune_serum0.88552111
46MP0003195_calcinosis0.87815233
47MP0005167_abnormal_blood-brain_barrier0.86679455
48MP0003941_abnormal_skin_development0.84355306
49MP0001501_abnormal_sleep_pattern0.82613539
50MP0002452_abnormal_antigen_presenting0.81618640
51MP0002405_respiratory_system_inflammati0.79071159
52MP0005025_abnormal_response_to0.78530099
53MP0008877_abnormal_DNA_methylation0.78393147
54MP0009785_altered_susceptibility_to0.78351593
55MP0003690_abnormal_glial_cell0.78302580
56MP0005666_abnormal_adipose_tissue0.77876795
57MP0000685_abnormal_immune_system0.75968160
58MP0001845_abnormal_inflammatory_respons0.73174100
59MP0002420_abnormal_adaptive_immunity0.72698507
60MP0005381_digestive/alimentary_phenotyp0.72098259
61MP0002998_abnormal_bone_remodeling0.70310226
62MP0005645_abnormal_hypothalamus_physiol0.69507513
63MP0001819_abnormal_immune_cell0.69377695
64MP0001873_stomach_inflammation0.68909518
65MP0004130_abnormal_muscle_cell0.67654561
66MP0004484_altered_response_of0.66513380
67MP0009765_abnormal_xenobiotic_induced0.65900802
68MP0005000_abnormal_immune_tolerance0.62790185
69MP0005367_renal/urinary_system_phenotyp0.61706653
70MP0000516_abnormal_urinary_system0.61706653
71MP0005448_abnormal_energy_balance0.59812084
72MP0003183_abnormal_peptide_metabolism0.59693413
73MP0005174_abnormal_tail_pigmentation0.57267500
74MP0001915_intracranial_hemorrhage0.57030678
75MP0001835_abnormal_antigen_presentation0.56776158
76MP0000716_abnormal_immune_system0.55560753
77MP0010155_abnormal_intestine_physiology0.55459892
78MP0004043_abnormal_pH_regulation0.55441106
79MP0000750_abnormal_muscle_regeneration0.55374228
80MP0009250_abnormal_appendicular_skeleto0.54518218
81MP0005395_other_phenotype0.54326084
82MP0004885_abnormal_endolymph0.53341319
83MP0005365_abnormal_bile_salt0.52818139
84MP0000465_gastrointestinal_hemorrhage0.52639495
85MP0001286_abnormal_eye_development0.50703225
86MP0008789_abnormal_olfactory_epithelium0.49423752
87MP0002133_abnormal_respiratory_system0.49289425
88MP0005388_respiratory_system_phenotype0.49289425
89MP0002933_joint_inflammation0.49043796
90MP0002127_abnormal_cardiovascular_syste0.48233413
91MP0005195_abnormal_posterior_eye0.46732038
92MP0006082_CNS_inflammation0.46689601
93MP0001533_abnormal_skeleton_physiology0.46343511
94MP0002429_abnormal_blood_cell0.46212736
95MP0000343_altered_response_to0.46035887
96MP0005386_behavior/neurological_phenoty0.45267901
97MP0004924_abnormal_behavior0.45267901
98MP0002398_abnormal_bone_marrow0.44753245
99MP0008004_abnormal_stomach_pH0.44514711
100MP0000613_abnormal_salivary_gland0.43148231

Predicted human phenotypes

RankGene SetZ-score
1Acanthocytosis (HP:0001927)9.12781994
2Disinhibition (HP:0000734)7.63260381
3Pendular nystagmus (HP:0012043)7.36522404
4Personality changes (HP:0000751)7.28655558
5Decreased central vision (HP:0007663)7.23484343
6Abnormal rod and cone electroretinograms (HP:0008323)6.33673726
7Self-mutilation (HP:0000742)6.06084944
8Acute hepatic failure (HP:0006554)5.39630707
9Increased corneal curvature (HP:0100692)5.25660448
10Keratoconus (HP:0000563)5.25660448
11Attenuation of retinal blood vessels (HP:0007843)4.81974248
12Dyskinesia (HP:0100660)4.81583947
13Cerebral hypomyelination (HP:0006808)4.71323069
14Inappropriate behavior (HP:0000719)4.70599162
15Irregular epiphyses (HP:0010582)4.61645299
16Psychosis (HP:0000709)3.47611801
17Carpal bone hypoplasia (HP:0001498)3.36515310
18Poikilocytosis (HP:0004447)3.35780958
19Delusions (HP:0000746)3.20409648
20Scanning speech (HP:0002168)3.19466659
21Upper motor neuron abnormality (HP:0002127)3.19150946
22Choreoathetosis (HP:0001266)3.16381301
23Recurrent sinusitis (HP:0011108)3.15974642
24Memory impairment (HP:0002354)2.94817583
25Vasculitis (HP:0002633)2.91139140
26Premature ovarian failure (HP:0008209)2.90597822
27CNS hypomyelination (HP:0003429)2.84340101
28Drooling (HP:0002307)2.79748258
29Excessive salivation (HP:0003781)2.78316705
30Macular degeneration (HP:0000608)2.69331892
31Oligomenorrhea (HP:0000876)2.66599940
32Agitation (HP:0000713)2.64252936
33Abnormality of fatty-acid metabolism (HP:0004359)2.41989854
34Elevated erythrocyte sedimentation rate (HP:0003565)2.41312359
35IgM deficiency (HP:0002850)2.35935249
36Plagiocephaly (HP:0001357)2.32426928
37Secondary amenorrhea (HP:0000869)2.28479454
38Gastrointestinal stroma tumor (HP:0100723)2.17768082
39Postnatal microcephaly (HP:0005484)2.12515680
40Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.09810520
41Stomach cancer (HP:0012126)2.08877310
42Limb hypertonia (HP:0002509)2.07104882
43Distal lower limb muscle weakness (HP:0009053)2.03172682
44Anxiety (HP:0000739)2.03103158
45Intellectual disability, profound (HP:0002187)2.02277486
46Agnosia (HP:0010524)2.02181165
47Abnormality of the costochondral junction (HP:0000919)2.01568819
48Absent rod-and cone-mediated responses on ERG (HP:0007688)10.0983818
49Striae distensae (HP:0001065)1.97524696
50Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.97308174
51Progressive external ophthalmoplegia (HP:0000590)1.96893179
52Myositis (HP:0100614)1.96368194
53Abnormality of lateral ventricle (HP:0030047)1.95484331
54Volvulus (HP:0002580)1.92594404
55Gastrointestinal infarctions (HP:0005244)1.91515062
56Infantile muscular hypotonia (HP:0008947)1.90773379
57Toxemia of pregnancy (HP:0100603)1.90170172
58Flat acetabular roof (HP:0003180)1.89337568
59Abnormality of the basal ganglia (HP:0002134)1.86169593
60Pallor (HP:0000980)1.85823307
61Retrobulbar optic neuritis (HP:0100654)1.83924413
62Optic neuritis (HP:0100653)1.83924413
63Combined immunodeficiency (HP:0005387)1.80955864
64Rhabdomyosarcoma (HP:0002859)1.79779769
65Unsteady gait (HP:0002317)1.78784814
66Lissencephaly (HP:0001339)1.78570690
67Hemiplegia (HP:0002301)1.77639546
68Generalized myoclonic seizures (HP:0002123)1.76802136
69Hyperphosphaturia (HP:0003109)1.74614050
70Spinal canal stenosis (HP:0003416)1.73084983
71Gaze-evoked nystagmus (HP:0000640)1.72425016
72Increased hepatocellular lipid droplets (HP:0006565)1.70848556
73Glucose intolerance (HP:0000833)1.70597761
74Infertility (HP:0000789)1.68109559
75Abnormality of salivation (HP:0100755)1.66596369
76Popliteal pterygium (HP:0009756)1.66357152
77Biliary tract neoplasm (HP:0100574)1.63962975
78Orchitis (HP:0100796)1.63856089
79Beaking of vertebral bodies (HP:0004568)1.63449336
80Emotional lability (HP:0000712)1.63381240
81Nasal polyposis (HP:0100582)1.63210459
82Dynein arm defect of respiratory motile cilia (HP:0012255)1.63098386
83Absent/shortened dynein arms (HP:0200106)1.63098386
84Abnormality of the pubic bones (HP:0003172)1.57958109
85Hyperglycinemia (HP:0002154)1.56733246
86Aggressive behavior (HP:0000718)1.56316190
87Menstrual irregularities (HP:0000858)1.56233167
88Chronic otitis media (HP:0000389)1.55969394
89Hypobetalipoproteinemia (HP:0003563)1.54272289
90Intention tremor (HP:0002080)1.53527702
91Delayed myelination (HP:0012448)1.52525475
92Barrel-shaped chest (HP:0001552)1.52196396
93Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.51809446
94Decreased muscle mass (HP:0003199)1.51042440
95Joint swelling (HP:0001386)1.47716190
96Abnormality of saccadic eye movements (HP:0000570)1.46150787
97Delayed CNS myelination (HP:0002188)1.45742484
98Ascites (HP:0001541)1.45716898
99Deformed sella turcica (HP:0002681)1.45213542
100Restlessness (HP:0000711)1.44234660

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME27.93507052
2RIPK46.47231779
3BMPR25.58094316
4MAP4K14.87619655
5CCNB14.09979439
6WNK33.41199235
7GRK62.87990238
8TTK2.09512489
9ACVR1B1.74067822
10PIK3CG1.60206028
11MAP3K111.42350533
12CSK1.41258926
13MAP3K131.28449012
14PDK21.19616873
15MAP3K41.10845090
16ERBB31.09580779
17TYK21.07597499
18BMPR1B1.06894365
19LRRK21.06506235
20MUSK1.05057544
21CDK61.04369340
22ZAK1.03295931
23PINK10.98539408
24FRK0.88613896
25TXK0.86811953
26BLK0.85490399
27ERBB40.81530038
28SYK0.75236139
29MAP3K10.74524511
30TNK20.71699524
31PLK10.69159606
32PRKCQ0.67945418
33PRKCG0.66637378
34MAP3K60.65363143
35LCK0.60380202
36PRKACA0.60362451
37TBK10.58763668
38TEC0.58361812
39PRKD20.57270672
40PRKACG0.57128287
41PKN10.54881074
42IKBKB0.51021206
43MARK30.50748814
44WEE10.49499472
45TAOK30.48995766
46PIM10.48953227
47OBSCN0.48315053
48IRAK40.47140014
49JAK10.44565923
50RPS6KA60.44444566
51TGFBR10.42993059
52FYN0.42003204
53OXSR10.41686564
54INSRR0.41644311
55EGFR0.40324508
56LYN0.38796004
57PRKCZ0.37744427
58GRK10.37198486
59CSNK1D0.36961108
60CAMK10.36757492
61ABL20.36308206
62TESK20.35857140
63MKNK20.35337978
64BTK0.34580679
65MAP2K30.34477036
66PRKCB0.33567011
67CDK40.31537025
68PDK10.30674395
69KIT0.30643498
70ADRBK10.30563025
71MAP4K20.29951273
72LMTK20.29612382
73ERBB20.29317646
74CSNK2A10.28503323
75PRKCA0.27724872
76RPS6KB10.27257995
77ROCK10.27044360
78NEK10.26657929
79PRKG10.26504478
80MAP2K60.26275425
81GRK70.26260709
82MATK0.26260102
83WNK10.26220594
84CDC42BPA0.26079080
85PRKCE0.26005288
86PASK0.25628483
87RPS6KC10.24874471
88RPS6KL10.24874471
89RPS6KA50.24796536
90STK100.24612497
91CHUK0.23796882
92CAMKK10.23229173
93CSNK2A20.23163851
94MAPK130.22653408
95BRD40.21518789
96MYLK0.21177458
97IRAK20.21036870
98SGK20.20389013
99SRC0.19895805
100SGK10.19616282

Predicted pathways (KEGG)

RankGene SetZ-score
1Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.71894963
2Primary bile acid biosynthesis_Homo sapiens_hsa001203.65586252
3Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.59915627
4Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.32151242
5Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.05251488
6Primary immunodeficiency_Homo sapiens_hsa053402.48603304
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.36057146
8Graft-versus-host disease_Homo sapiens_hsa053322.14205592
9Staphylococcus aureus infection_Homo sapiens_hsa051502.13753965
10PPAR signaling pathway_Homo sapiens_hsa033201.99633891
11Glycerophospholipid metabolism_Homo sapiens_hsa005641.90307638
12Sphingolipid signaling pathway_Homo sapiens_hsa040711.67732791
13Notch signaling pathway_Homo sapiens_hsa043301.57803840
14Selenocompound metabolism_Homo sapiens_hsa004501.56987509
15Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.55903417
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.55820390
17African trypanosomiasis_Homo sapiens_hsa051431.54655147
18ABC transporters_Homo sapiens_hsa020101.51668422
19Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.51550785
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.49014174
21Leishmaniasis_Homo sapiens_hsa051401.47748939
22Olfactory transduction_Homo sapiens_hsa047401.47224337
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.44123990
24Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.41685398
25Autoimmune thyroid disease_Homo sapiens_hsa053201.38468422
26Allograft rejection_Homo sapiens_hsa053301.34750826
27Sulfur relay system_Homo sapiens_hsa041221.33831549
28Carbohydrate digestion and absorption_Homo sapiens_hsa049731.32466137
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.31994513
30Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.31952944
31Pancreatic secretion_Homo sapiens_hsa049721.28675617
32Pertussis_Homo sapiens_hsa051331.23145632
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.18351806
34Phagosome_Homo sapiens_hsa041451.13589661
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.12184683
36Type I diabetes mellitus_Homo sapiens_hsa049401.06867532
37RNA degradation_Homo sapiens_hsa030181.05535108
38Fat digestion and absorption_Homo sapiens_hsa049751.00009894
39Complement and coagulation cascades_Homo sapiens_hsa046100.97995829
40Hematopoietic cell lineage_Homo sapiens_hsa046400.97161186
41Dorso-ventral axis formation_Homo sapiens_hsa043200.96415348
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.96086919
43Ribosome_Homo sapiens_hsa030100.96037223
44Asthma_Homo sapiens_hsa053100.95001983
45SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94450494
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.93767565
47Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88771107
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.88292268
49Mineral absorption_Homo sapiens_hsa049780.87854647
50T cell receptor signaling pathway_Homo sapiens_hsa046600.86837123
51Osteoclast differentiation_Homo sapiens_hsa043800.86458784
52Leukocyte transendothelial migration_Homo sapiens_hsa046700.86089184
53Malaria_Homo sapiens_hsa051440.85516748
54Salivary secretion_Homo sapiens_hsa049700.83280878
55Tuberculosis_Homo sapiens_hsa051520.83179151
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83002533
57B cell receptor signaling pathway_Homo sapiens_hsa046620.78959142
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78351404
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76827773
60Chemokine signaling pathway_Homo sapiens_hsa040620.72995146
61Morphine addiction_Homo sapiens_hsa050320.72806093
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69279012
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.67907367
64Linoleic acid metabolism_Homo sapiens_hsa005910.65553884
65Protein digestion and absorption_Homo sapiens_hsa049740.64585274
66Chemical carcinogenesis_Homo sapiens_hsa052040.63665349
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.62378259
68Arachidonic acid metabolism_Homo sapiens_hsa005900.57929965
69Retinol metabolism_Homo sapiens_hsa008300.57361312
70Nicotine addiction_Homo sapiens_hsa050330.55578224
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55490777
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55037768
73Histidine metabolism_Homo sapiens_hsa003400.54841600
74Colorectal cancer_Homo sapiens_hsa052100.53580102
75Nitrogen metabolism_Homo sapiens_hsa009100.52893835
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51657789
77Rap1 signaling pathway_Homo sapiens_hsa040150.49209301
78Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.46268598
79Endocytosis_Homo sapiens_hsa041440.44697028
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43526733
81Antigen processing and presentation_Homo sapiens_hsa046120.43463483
82Vitamin digestion and absorption_Homo sapiens_hsa049770.43028869
83Glutathione metabolism_Homo sapiens_hsa004800.39961043
84Influenza A_Homo sapiens_hsa051640.37916574
85Insulin secretion_Homo sapiens_hsa049110.36060049
86Rheumatoid arthritis_Homo sapiens_hsa053230.35915379
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.35448982
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.34251572
89Measles_Homo sapiens_hsa051620.31871359
90Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.31824925
91Legionellosis_Homo sapiens_hsa051340.30760740
92Gastric acid secretion_Homo sapiens_hsa049710.29513809
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.28365632
94Herpes simplex infection_Homo sapiens_hsa051680.27434763
95Ras signaling pathway_Homo sapiens_hsa040140.27420745
96Collecting duct acid secretion_Homo sapiens_hsa049660.27220141
97Platelet activation_Homo sapiens_hsa046110.26799194
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.26765933
99GABAergic synapse_Homo sapiens_hsa047270.26016955
100Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.25763396

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »