C2ORF81

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)7.41012344
2cilium or flagellum-dependent cell motility (GO:0001539)7.22399878
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.19813114
4epithelial cilium movement (GO:0003351)6.70018401
5cilium movement (GO:0003341)6.65332464
6axoneme assembly (GO:0035082)5.53406392
7behavioral response to nicotine (GO:0035095)5.25857586
8motile cilium assembly (GO:0044458)4.99847551
9regulation of cilium movement (GO:0003352)4.67281393
10L-fucose catabolic process (GO:0042355)4.31571062
11fucose catabolic process (GO:0019317)4.31571062
12L-fucose metabolic process (GO:0042354)4.31571062
13cilium organization (GO:0044782)4.05737243
14cilium assembly (GO:0042384)3.94008276
15protein localization to cilium (GO:0061512)3.88252238
16response to pheromone (GO:0019236)3.79060214
17intraciliary transport (GO:0042073)3.76455875
18cilium morphogenesis (GO:0060271)3.70152139
19indolalkylamine metabolic process (GO:0006586)3.66921219
20DNA deamination (GO:0045006)3.63586624
21tryptophan catabolic process (GO:0006569)3.61228990
22indole-containing compound catabolic process (GO:0042436)3.61228990
23indolalkylamine catabolic process (GO:0046218)3.61228990
24kynurenine metabolic process (GO:0070189)3.47332535
25detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.44678893
26nonmotile primary cilium assembly (GO:0035058)3.36154022
27protein polyglutamylation (GO:0018095)3.35490381
28regulation of microtubule-based movement (GO:0060632)3.31720463
29cellular ketone body metabolic process (GO:0046950)3.28658451
30left/right axis specification (GO:0070986)3.24291553
31tryptophan metabolic process (GO:0006568)3.21171891
32detection of light stimulus involved in visual perception (GO:0050908)3.18073324
33detection of light stimulus involved in sensory perception (GO:0050962)3.18073324
34photoreceptor cell maintenance (GO:0045494)3.14167435
35retinal cone cell development (GO:0046549)3.08003859
36left/right pattern formation (GO:0060972)3.07831780
37cornea development in camera-type eye (GO:0061303)3.06538225
38cellular component assembly involved in morphogenesis (GO:0010927)3.05245202
39water-soluble vitamin biosynthetic process (GO:0042364)2.99889292
40indole-containing compound metabolic process (GO:0042430)2.98003793
41negative regulation of telomere maintenance (GO:0032205)2.97849373
42ketone body metabolic process (GO:1902224)2.97792636
43microtubule bundle formation (GO:0001578)2.96347082
44neural tube formation (GO:0001841)2.96231157
45rRNA catabolic process (GO:0016075)2.93825712
46negative regulation of T cell differentiation in thymus (GO:0033085)2.92243667
47platelet dense granule organization (GO:0060155)2.92183716
48centriole replication (GO:0007099)2.88511923
49piRNA metabolic process (GO:0034587)2.88361502
50neuronal action potential (GO:0019228)2.83026858
51sperm motility (GO:0030317)2.78441266
52sulfation (GO:0051923)2.77766811
53negative regulation of cytosolic calcium ion concentration (GO:0051481)2.76534496
54response to xenobiotic stimulus (GO:0009410)2.75956023
55preassembly of GPI anchor in ER membrane (GO:0016254)2.75847986
56exogenous drug catabolic process (GO:0042738)2.75225995
57primary amino compound metabolic process (GO:1901160)2.74864828
58kidney morphogenesis (GO:0060993)2.71385236
59serotonin metabolic process (GO:0042428)2.70344650
60gamma-aminobutyric acid transport (GO:0015812)2.69367653
61multicellular organism reproduction (GO:0032504)2.66416997
62benzene-containing compound metabolic process (GO:0042537)2.62764611
63photoreceptor cell development (GO:0042461)2.61685873
64drug catabolic process (GO:0042737)2.60241978
65protein complex biogenesis (GO:0070271)2.58720421
66smoothened signaling pathway (GO:0007224)2.58645438
67respiratory chain complex IV assembly (GO:0008535)2.58522580
68centriole assembly (GO:0098534)2.56668774
69behavioral response to ethanol (GO:0048149)2.56637396
70cellular biogenic amine catabolic process (GO:0042402)2.55767147
71amine catabolic process (GO:0009310)2.55767147
72spinal cord motor neuron differentiation (GO:0021522)2.54922514
73DNA methylation involved in gamete generation (GO:0043046)2.53650115
74mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.51986918
75mitochondrial respiratory chain complex I assembly (GO:0032981)2.51986918
76NADH dehydrogenase complex assembly (GO:0010257)2.51986918
77ventricular system development (GO:0021591)2.50137335
78G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.50017406
79RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.49986160
80tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.49986160
81reflex (GO:0060004)2.49567743
82neurotransmitter metabolic process (GO:0042133)2.48496909
83auditory receptor cell stereocilium organization (GO:0060088)2.48342186
84regulation of rhodopsin mediated signaling pathway (GO:0022400)2.47548390
85cell projection assembly (GO:0030031)2.45191372
86rhodopsin mediated signaling pathway (GO:0016056)2.45102083
87determination of left/right symmetry (GO:0007368)2.44726187
88thyroid hormone metabolic process (GO:0042403)2.43619608
89synaptic transmission, cholinergic (GO:0007271)2.43268435
90mannosylation (GO:0097502)2.41968879
91cytochrome complex assembly (GO:0017004)2.41864366
92positive regulation of fatty acid transport (GO:2000193)2.40774722
93regulation of collateral sprouting (GO:0048670)2.39625917
94inner ear receptor stereocilium organization (GO:0060122)2.39603429
95positive regulation of oligodendrocyte differentiation (GO:0048714)2.38965370
96transmission of nerve impulse (GO:0019226)2.38895457
97regulation of hippo signaling (GO:0035330)2.38022229
98regulation of action potential (GO:0098900)2.37902148
99ubiquinone biosynthetic process (GO:0006744)2.36400535
100reciprocal DNA recombination (GO:0035825)2.33663040

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.74548999
2VDR_22108803_ChIP-Seq_LS180_Human3.36681169
3EZH2_22144423_ChIP-Seq_EOC_Human2.77678189
4GBX2_23144817_ChIP-Seq_PC3_Human2.75142180
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.60832773
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.49094850
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.41996204
8IGF1R_20145208_ChIP-Seq_DFB_Human2.33578062
9CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18929305
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14309589
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.10682421
12CTBP1_25329375_ChIP-Seq_LNCAP_Human2.09167299
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.00164588
14TAF15_26573619_Chip-Seq_HEK293_Human2.00114182
15ER_23166858_ChIP-Seq_MCF-7_Human1.95278516
16EWS_26573619_Chip-Seq_HEK293_Human1.95226243
17FUS_26573619_Chip-Seq_HEK293_Human1.94015251
18P300_19829295_ChIP-Seq_ESCs_Human1.86592544
19EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.80114882
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73140898
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65458838
22PIAS1_25552417_ChIP-Seq_VCAP_Human1.64014880
23BCAT_22108803_ChIP-Seq_LS180_Human1.63068163
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.62042400
25STAT3_23295773_ChIP-Seq_U87_Human1.57259366
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.55524490
27NR3C1_21868756_ChIP-Seq_MCF10A_Human1.55350166
28SMAD4_21799915_ChIP-Seq_A2780_Human1.49682103
29CBP_20019798_ChIP-Seq_JUKART_Human1.49395239
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.49395239
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.49257538
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.48272756
33REST_21632747_ChIP-Seq_MESCs_Mouse1.46589295
34POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.45704361
35TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45704361
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45504951
37TCF4_23295773_ChIP-Seq_U87_Human1.45454810
38TP53_22573176_ChIP-Seq_HFKS_Human1.44838343
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43179405
40SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39943746
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38785526
42AR_25329375_ChIP-Seq_VCAP_Human1.38594252
43BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36949852
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36730511
45DROSHA_22980978_ChIP-Seq_HELA_Human1.36704525
46* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.36513602
47* FOXA1_25329375_ChIP-Seq_VCAP_Human1.36513602
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35082870
49SOX2_19829295_ChIP-Seq_ESCs_Human1.34542239
50NANOG_19829295_ChIP-Seq_ESCs_Human1.34542239
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33997255
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33941300
53TCF4_22108803_ChIP-Seq_LS180_Human1.33465289
54IRF1_19129219_ChIP-ChIP_H3396_Human1.32268620
55PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.31598344
56AR_21572438_ChIP-Seq_LNCaP_Human1.30108885
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27750532
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.26597853
59RUNX2_22187159_ChIP-Seq_PCA_Human1.25242784
60GATA3_21878914_ChIP-Seq_MCF-7_Human1.24895981
61NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24772146
62GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.24312461
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24043639
64AR_20517297_ChIP-Seq_VCAP_Human1.23130162
65KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20043018
66ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19856936
67NCOR_22424771_ChIP-Seq_293T_Human1.19032352
68MYC_18940864_ChIP-ChIP_HL60_Human1.18656079
69NFE2_27457419_Chip-Seq_LIVER_Mouse1.18586834
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.18298267
71HOXB7_26014856_ChIP-Seq_BT474_Human1.18065460
72FOXA1_21572438_ChIP-Seq_LNCaP_Human1.17049438
73PRDM14_20953172_ChIP-Seq_ESCs_Human1.16793817
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.16291783
75RNF2_27304074_Chip-Seq_NSC_Mouse1.14116758
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.13058018
77TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11072734
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.09253496
79RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08543617
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07378747
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.07005683
82E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.05888683
83SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04612205
84MYC_19829295_ChIP-Seq_ESCs_Human1.03064324
85ARNT_22903824_ChIP-Seq_MCF-7_Human0.99163806
86PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97812073
87CDX2_22108803_ChIP-Seq_LS180_Human0.97516400
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97373469
89ERA_21632823_ChIP-Seq_H3396_Human0.96861512
90OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96834248
91TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96184518
92NANOG_18555785_Chip-Seq_ESCs_Mouse0.95446121
93ETV1_20927104_ChIP-Seq_GIST48_Human0.95316924
94CRX_20693478_ChIP-Seq_RETINA_Mouse0.95027799
95FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.94806532
96P53_22387025_ChIP-Seq_ESCs_Mouse0.94699151
97GABP_17652178_ChIP-ChIP_JURKAT_Human0.94144540
98AHR_22903824_ChIP-Seq_MCF-7_Human0.93771773
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.92999390
100CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.92966726

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok2.98768221
2MP0002653_abnormal_ependyma_morphology2.82769218
3MP0008877_abnormal_DNA_methylation2.59187337
4MP0004043_abnormal_pH_regulation2.44813114
5MP0005551_abnormal_eye_electrophysiolog2.43265270
6MP0003195_calcinosis2.36620369
7MP0002102_abnormal_ear_morphology2.34260214
8MP0001968_abnormal_touch/_nociception2.30277942
9MP0009046_muscle_twitch2.15073783
10MP0001984_abnormal_olfaction2.13042563
11MP0004133_heterotaxia2.12108946
12MP0003136_yellow_coat_color2.07456153
13MP0002638_abnormal_pupillary_reflex2.04318026
14MP0005646_abnormal_pituitary_gland1.99197345
15MP0002876_abnormal_thyroid_physiology1.97679563
16MP0003787_abnormal_imprinting1.92240144
17MP0009745_abnormal_behavioral_response1.89911964
18MP0004142_abnormal_muscle_tone1.86839229
19MP0001986_abnormal_taste_sensitivity1.86146100
20MP0008872_abnormal_physiological_respon1.85714361
21MP0000569_abnormal_digit_pigmentation1.82926235
22MP0005253_abnormal_eye_physiology1.79124076
23MP0002736_abnormal_nociception_after1.77991976
24MP0006072_abnormal_retinal_apoptosis1.77708423
25MP0003878_abnormal_ear_physiology1.74645057
26MP0005377_hearing/vestibular/ear_phenot1.74645057
27MP0004885_abnormal_endolymph1.73074998
28MP0006292_abnormal_olfactory_placode1.72604444
29MP0001485_abnormal_pinna_reflex1.67943477
30MP0003646_muscle_fatigue1.67898006
31MP0003880_abnormal_central_pattern1.67146218
32MP0002837_dystrophic_cardiac_calcinosis1.66522232
33MP0006276_abnormal_autonomic_nervous1.64052607
34MP0002272_abnormal_nervous_system1.63842325
35MP0001501_abnormal_sleep_pattern1.63739863
36MP0002735_abnormal_chemical_nociception1.62123181
37MP0005645_abnormal_hypothalamus_physiol1.60506779
38MP0000427_abnormal_hair_cycle1.54855730
39MP0000383_abnormal_hair_follicle1.51017353
40MP0000372_irregular_coat_pigmentation1.50971688
41MP0001486_abnormal_startle_reflex1.49444751
42MP0004147_increased_porphyrin_level1.45851773
43MP0002160_abnormal_reproductive_system1.43799234
44MP0000631_abnormal_neuroendocrine_gland1.39282108
45MP0002572_abnormal_emotion/affect_behav1.34870976
46MP0002928_abnormal_bile_duct1.32833001
47MP0005389_reproductive_system_phenotype1.30934974
48MP0002064_seizures1.26940585
49MP0002277_abnormal_respiratory_mucosa1.26879524
50MP0001970_abnormal_pain_threshold1.26798585
51MP0010386_abnormal_urinary_bladder1.26761554
52MP0002557_abnormal_social/conspecific_i1.26082304
53MP0002938_white_spotting1.24715091
54MP0001529_abnormal_vocalization1.18910333
55MP0003011_delayed_dark_adaptation1.18674751
56MP0005084_abnormal_gallbladder_morpholo1.18541573
57MP0008789_abnormal_olfactory_epithelium1.18479026
58MP0005174_abnormal_tail_pigmentation1.18137125
59MP0004742_abnormal_vestibular_system1.17603272
60MP0002733_abnormal_thermal_nociception1.12531602
61MP0002909_abnormal_adrenal_gland1.11942252
62MP0002067_abnormal_sensory_capabilities1.10625947
63MP0002734_abnormal_mechanical_nocicepti1.06648141
64MP0003635_abnormal_synaptic_transmissio1.06026370
65MP0004924_abnormal_behavior1.03669480
66MP0005386_behavior/neurological_phenoty1.03669480
67MP0005195_abnormal_posterior_eye1.01273964
68MP0002063_abnormal_learning/memory/cond1.00417155
69MP0001919_abnormal_reproductive_system0.96646385
70MP0003698_abnormal_male_reproductive0.96587239
71MP0001324_abnormal_eye_pigmentation0.96141149
72MP0001905_abnormal_dopamine_level0.94459787
73MP0005075_abnormal_melanosome_morpholog0.93611849
74MP0000026_abnormal_inner_ear0.92979306
75MP0002234_abnormal_pharynx_morphology0.92317193
76MP0005410_abnormal_fertilization0.91945625
77MP0005423_abnormal_somatic_nervous0.91563830
78MP0005083_abnormal_biliary_tract0.91436035
79MP0002229_neurodegeneration0.91075707
80MP0001963_abnormal_hearing_physiology0.87607344
81MP0005085_abnormal_gallbladder_physiolo0.86977711
82MP0003718_maternal_effect0.85178273
83MP0004145_abnormal_muscle_electrophysio0.85129683
84MP0001929_abnormal_gametogenesis0.84927119
85MP0002752_abnormal_somatic_nervous0.84555559
86MP0001502_abnormal_circadian_rhythm0.83377461
87MP0002095_abnormal_skin_pigmentation0.80417121
88MP0000230_abnormal_systemic_arterial0.80030844
89MP0000538_abnormal_urinary_bladder0.79630112
90MP0008995_early_reproductive_senescence0.77839055
91MP0002138_abnormal_hepatobiliary_system0.77436481
92MP0001765_abnormal_ion_homeostasis0.74677006
93MP0004019_abnormal_vitamin_homeostasis0.73686243
94MP0003890_abnormal_embryonic-extraembry0.73306372
95MP0005394_taste/olfaction_phenotype0.72369696
96MP0005499_abnormal_olfactory_system0.72369696
97MP0003283_abnormal_digestive_organ0.71874340
98MP0008775_abnormal_heart_ventricle0.71589037
99MP0009780_abnormal_chondrocyte_physiolo0.70769601
100MP0008058_abnormal_DNA_repair0.70719117

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)5.90901536
2Abnormal respiratory motile cilium morphology (HP:0005938)5.90901536
3Dynein arm defect of respiratory motile cilia (HP:0012255)5.79251820
4Absent/shortened dynein arms (HP:0200106)5.79251820
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.52157957
6Abnormal ciliary motility (HP:0012262)5.44807970
7Abnormal respiratory motile cilium physiology (HP:0012261)5.29426754
8Pancreatic cysts (HP:0001737)4.98316130
9Pancreatic fibrosis (HP:0100732)4.83916253
10Rhinitis (HP:0012384)4.68912180
11True hermaphroditism (HP:0010459)4.65996522
12Abnormality of midbrain morphology (HP:0002418)4.54965998
13Molar tooth sign on MRI (HP:0002419)4.54965998
14Nephronophthisis (HP:0000090)4.30341259
15Abnormality of the renal medulla (HP:0100957)3.68443019
16Cystic liver disease (HP:0006706)3.57021325
17Congenital stationary night blindness (HP:0007642)3.51884651
18Bronchiectasis (HP:0002110)3.48730687
19Chronic bronchitis (HP:0004469)3.38895499
20Chronic hepatic failure (HP:0100626)3.36621809
21Medial flaring of the eyebrow (HP:0010747)3.34910478
22Abnormality of the renal cortex (HP:0011035)3.12044914
23Tubular atrophy (HP:0000092)2.85625817
24Gait imbalance (HP:0002141)2.77779115
25Hyperventilation (HP:0002883)2.72808682
26Congenital hepatic fibrosis (HP:0002612)2.69374275
27Occipital encephalocele (HP:0002085)2.69246689
28Anencephaly (HP:0002323)2.66711734
29Congenital primary aphakia (HP:0007707)2.66509899
30Sclerocornea (HP:0000647)2.62887150
31Aplasia/Hypoplasia of the tongue (HP:0010295)2.62655767
32Type II lissencephaly (HP:0007260)2.60016590
33Postaxial foot polydactyly (HP:0001830)2.59420638
34Attenuation of retinal blood vessels (HP:0007843)2.57747737
35Nephrogenic diabetes insipidus (HP:0009806)2.51474234
36Polydipsia (HP:0001959)2.50891948
37Abnormal drinking behavior (HP:0030082)2.50891948
38Furrowed tongue (HP:0000221)2.44912227
39Chronic sinusitis (HP:0011109)2.40086128
40Decreased circulating renin level (HP:0003351)2.39095057
41Male pseudohermaphroditism (HP:0000037)2.38528857
42Abolished electroretinogram (ERG) (HP:0000550)2.34319249
43Abnormal biliary tract physiology (HP:0012439)2.33802472
44Bile duct proliferation (HP:0001408)2.33802472
45Abnormal rod and cone electroretinograms (HP:0008323)2.33697708
46Decreased central vision (HP:0007663)2.16425218
47Gaze-evoked nystagmus (HP:0000640)2.14266282
48Genital tract atresia (HP:0001827)2.12334240
49Congenital, generalized hypertrichosis (HP:0004540)2.10579120
50Polyuria (HP:0000103)2.09605510
51Aplasia/Hypoplasia of the spleen (HP:0010451)2.08503212
52Vaginal atresia (HP:0000148)2.07200085
53Broad-based gait (HP:0002136)2.04171896
54Progressive cerebellar ataxia (HP:0002073)2.02900653
55Postaxial hand polydactyly (HP:0001162)2.02302033
56Large for gestational age (HP:0001520)1.99670986
57Asplenia (HP:0001746)1.98827352
58Nasal polyposis (HP:0100582)1.97060766
59Lissencephaly (HP:0001339)1.94186406
60Inability to walk (HP:0002540)1.94128515
61Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93844068
62Pendular nystagmus (HP:0012043)1.92091772
63Bony spicule pigmentary retinopathy (HP:0007737)1.90489906
64Recurrent sinusitis (HP:0011108)1.90331733
65Increased corneal curvature (HP:0100692)1.89889343
66Keratoconus (HP:0000563)1.89889343
67Infertility (HP:0000789)1.89578904
68Bronchitis (HP:0012387)1.88611009
69Abnormality of alanine metabolism (HP:0010916)1.87754155
70Hyperalaninemia (HP:0003348)1.87754155
71Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.87754155
72Poor coordination (HP:0002370)1.86102200
73Preaxial hand polydactyly (HP:0001177)1.84552418
74Tubulointerstitial nephritis (HP:0001970)1.84469759
75Absent speech (HP:0001344)1.83973679
76Renal cortical cysts (HP:0000803)1.83558087
77Retinitis pigmentosa (HP:0000510)1.76385040
78Progressive inability to walk (HP:0002505)1.76180029
79Aplasia/Hypoplasia of the tibia (HP:0005772)1.75534902
80Protruding tongue (HP:0010808)1.75373490
81Oculomotor apraxia (HP:0000657)1.74477664
82Genetic anticipation (HP:0003743)1.73027509
83Cerebellar dysplasia (HP:0007033)1.72255742
84Hypothermia (HP:0002045)1.71945828
85Stomach cancer (HP:0012126)1.71292927
86Mitochondrial inheritance (HP:0001427)1.70521844
87Chronic otitis media (HP:0000389)1.69619698
88Concave nail (HP:0001598)1.67707790
89Decreased electroretinogram (ERG) amplitude (HP:0000654)1.67423813
90Abnormality of renin-angiotensin system (HP:0000847)1.66903642
91Increased CSF lactate (HP:0002490)1.66571653
92Tubulointerstitial abnormality (HP:0001969)1.65658047
93Acute necrotizing encephalopathy (HP:0006965)1.64475933
94Abnormality of the pons (HP:0007361)1.62409838
95Congenital sensorineural hearing impairment (HP:0008527)1.62044322
96Abnormal urine output (HP:0012590)1.62033981
97Febrile seizures (HP:0002373)1.61108494
98Hypoplasia of the pons (HP:0012110)1.59097329
99Optic disc pallor (HP:0000543)1.57689916
100Hemiparesis (HP:0001269)1.55297564

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.98680552
2BMPR1B3.34271415
3MAPK153.16255677
4ADRBK23.13208134
5ACVR1B2.75665804
6MAP4K22.60700615
7ZAK2.44271510
8TLK12.37215237
9GRK12.37044188
10WNK32.36455436
11CASK2.18434800
12NUAK12.16226257
13WNK42.06030976
14INSRR1.99337322
15MAPK131.96589294
16PINK11.96117603
17TAOK31.90566646
18TXK1.68074816
19MST41.55311645
20OXSR11.52271921
21DAPK21.49707534
22MAP3K41.48545103
23MAPKAPK31.36250916
24ADRBK11.28107929
25TNIK1.26107397
26TRIM281.20676796
27PAK31.20226022
28PNCK1.19571498
29STK391.18979318
30NME11.13014036
31CAMKK21.12417895
32MARK11.10140837
33MKNK21.10098079
34DYRK21.06740551
35PTK2B1.03939558
36TGFBR11.03518909
37PRKCE0.95118567
38MAP2K70.88681755
39PRKCG0.87623029
40VRK10.85828742
41NTRK30.84787447
42PLK20.80423726
43MUSK0.79720283
44STK160.78833467
45MAP2K60.76960115
46STK38L0.75980201
47PHKG10.74459391
48PHKG20.74459391
49BRSK20.70681013
50BCR0.67493661
51PRKCQ0.66679883
52PRKCI0.64741362
53IKBKB0.63932941
54TIE10.63747081
55TEC0.61574932
56EPHA40.59716521
57BCKDK0.58824256
58CSNK1G20.58231390
59CAMK2A0.56794758
60FGFR20.56732759
61PIK3CA0.56583340
62ERBB30.54676397
63CAMK10.52782156
64CHUK0.51508714
65IRAK10.51486455
66AKT30.49765948
67PKN10.49505648
68PRKACA0.49113608
69RPS6KA50.47356096
70ITK0.46326640
71EPHA30.45333412
72CSNK1G10.44849237
73CSNK1G30.41786503
74NTRK20.41557599
75MAPKAPK50.41552387
76KIT0.41269885
77NLK0.40061670
78GRK70.39613902
79CSNK1A10.38942732
80FER0.38535189
81STK110.38340195
82PRKCA0.36650162
83ERBB20.35584867
84NEK20.35171852
85MAP3K70.34945040
86PRKCZ0.34908278
87CSNK1A1L0.34866591
88CAMKK10.33950361
89PRKAA20.33549790
90TNK20.33337830
91CCNB10.33019003
92SGK20.32936491
93DYRK1A0.31746842
94PRKAA10.31358133
95MKNK10.31151690
96PRKG10.30166387
97TRPM70.29514550
98PLK30.29427381
99CSNK1D0.28837987
100MAP2K10.27618768

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.89602855
2Linoleic acid metabolism_Homo sapiens_hsa005912.73927885
3Nitrogen metabolism_Homo sapiens_hsa009102.47160066
4alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.37961741
5Caffeine metabolism_Homo sapiens_hsa002322.35617062
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.30824702
7Nicotine addiction_Homo sapiens_hsa050332.28499466
8Butanoate metabolism_Homo sapiens_hsa006502.18429773
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.17479908
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.09911180
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.03479372
12Oxidative phosphorylation_Homo sapiens_hsa001902.00521778
13Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.97096077
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.96898104
15Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.87460482
16Chemical carcinogenesis_Homo sapiens_hsa052041.85368325
17Tryptophan metabolism_Homo sapiens_hsa003801.82005450
18Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.73387377
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.72553418
20Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.70898256
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.69783335
22Ether lipid metabolism_Homo sapiens_hsa005651.62915923
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.62414053
24Taste transduction_Homo sapiens_hsa047421.59186098
25Homologous recombination_Homo sapiens_hsa034401.57666776
26Huntingtons disease_Homo sapiens_hsa050161.51650981
27Selenocompound metabolism_Homo sapiens_hsa004501.51506442
28Protein export_Homo sapiens_hsa030601.48069786
29Olfactory transduction_Homo sapiens_hsa047401.45870507
30Histidine metabolism_Homo sapiens_hsa003401.43633412
31Parkinsons disease_Homo sapiens_hsa050121.38591025
32Fanconi anemia pathway_Homo sapiens_hsa034601.38235689
33Basal transcription factors_Homo sapiens_hsa030221.37902123
34ABC transporters_Homo sapiens_hsa020101.35223317
35Intestinal immune network for IgA production_Homo sapiens_hsa046721.32165714
36RNA polymerase_Homo sapiens_hsa030201.32140710
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.29941064
38Peroxisome_Homo sapiens_hsa041461.27889132
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.24835465
40Morphine addiction_Homo sapiens_hsa050321.23975063
41beta-Alanine metabolism_Homo sapiens_hsa004101.21791246
42Retinol metabolism_Homo sapiens_hsa008301.21589152
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.09483840
44Serotonergic synapse_Homo sapiens_hsa047261.09417918
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.08839963
46Propanoate metabolism_Homo sapiens_hsa006401.07640778
47Arachidonic acid metabolism_Homo sapiens_hsa005901.07618036
48Cardiac muscle contraction_Homo sapiens_hsa042601.05665684
49Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.01311139
50Collecting duct acid secretion_Homo sapiens_hsa049660.99031493
51Circadian entrainment_Homo sapiens_hsa047130.95239721
52Insulin secretion_Homo sapiens_hsa049110.94787847
53Glutamatergic synapse_Homo sapiens_hsa047240.93604952
54GABAergic synapse_Homo sapiens_hsa047270.92770073
55Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.90637990
56Alzheimers disease_Homo sapiens_hsa050100.86595962
57Salivary secretion_Homo sapiens_hsa049700.86101432
58RNA degradation_Homo sapiens_hsa030180.86067140
59Regulation of autophagy_Homo sapiens_hsa041400.84914467
60Asthma_Homo sapiens_hsa053100.84306278
61Ovarian steroidogenesis_Homo sapiens_hsa049130.83716455
62Glycerolipid metabolism_Homo sapiens_hsa005610.76021399
63Calcium signaling pathway_Homo sapiens_hsa040200.74326874
64Type I diabetes mellitus_Homo sapiens_hsa049400.70482475
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.70064277
66Circadian rhythm_Homo sapiens_hsa047100.68659492
67Primary immunodeficiency_Homo sapiens_hsa053400.66400479
68One carbon pool by folate_Homo sapiens_hsa006700.63210933
69Purine metabolism_Homo sapiens_hsa002300.60801589
70Tyrosine metabolism_Homo sapiens_hsa003500.60342526
71Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59823977
72Metabolic pathways_Homo sapiens_hsa011000.59813230
73Graft-versus-host disease_Homo sapiens_hsa053320.59491074
74Autoimmune thyroid disease_Homo sapiens_hsa053200.53507177
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50716185
76Fatty acid degradation_Homo sapiens_hsa000710.49727389
77Dorso-ventral axis formation_Homo sapiens_hsa043200.49243516
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49014446
79Cocaine addiction_Homo sapiens_hsa050300.48193861
80Allograft rejection_Homo sapiens_hsa053300.47349236
81Hedgehog signaling pathway_Homo sapiens_hsa043400.47244315
82Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46443468
83Glutathione metabolism_Homo sapiens_hsa004800.45062652
84Dopaminergic synapse_Homo sapiens_hsa047280.44641786
85Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.43779660
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42283737
87Amphetamine addiction_Homo sapiens_hsa050310.40831563
88Mineral absorption_Homo sapiens_hsa049780.40014005
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39808700
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.39093050
91Fat digestion and absorption_Homo sapiens_hsa049750.38598202
92Sphingolipid metabolism_Homo sapiens_hsa006000.35987866
93cAMP signaling pathway_Homo sapiens_hsa040240.34829534
94Nucleotide excision repair_Homo sapiens_hsa034200.33126675
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.32994827
96Steroid biosynthesis_Homo sapiens_hsa001000.31644306
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.31568278
98Pyrimidine metabolism_Homo sapiens_hsa002400.31406378
99Sulfur metabolism_Homo sapiens_hsa009200.31092459
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30900188

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »