C20ORF141

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA packaging (GO:0006323)9.77240582
2sperm capacitation (GO:0048240)9.43951636
3single strand break repair (GO:0000012)8.76394014
4plasma membrane fusion (GO:0045026)8.75136999
5spermatid nucleus differentiation (GO:0007289)8.72549348
6microtubule depolymerization (GO:0007019)8.50396805
7spermatid development (GO:0007286)8.12686902
8sperm-egg recognition (GO:0035036)7.82560574
9sexual reproduction (GO:0019953)7.54386769
10binding of sperm to zona pellucida (GO:0007339)7.48572906
11rRNA methylation (GO:0031167)7.06211184
12multicellular organism reproduction (GO:0032504)7.03244949
13negative regulation of inclusion body assembly (GO:0090084)7.00701873
14reproduction (GO:0000003)6.92549526
15microtubule polymerization or depolymerization (GO:0031109)6.77770551
16calcium ion-dependent exocytosis (GO:0017156)6.74962108
17cell-cell recognition (GO:0009988)6.42552428
18protein polyglutamylation (GO:0018095)6.36051472
19antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.16346201
20phosphatidylethanolamine biosynthetic process (GO:0006646)6.13713069
21axonemal dynein complex assembly (GO:0070286)6.10679111
22spermatogenesis (GO:0007283)6.09043809
23cellular ketone body metabolic process (GO:0046950)6.07816645
24male gamete generation (GO:0048232)6.06930145
25rRNA modification (GO:0000154)5.96293285
26protein targeting to Golgi (GO:0000042)5.90894615
27establishment of protein localization to Golgi (GO:0072600)5.66036157
28phosphatidylethanolamine metabolic process (GO:0046337)5.65239570
29microtubule severing (GO:0051013)5.60840598
30gamete generation (GO:0007276)5.53997046
31retrograde transport, vesicle recycling within Golgi (GO:0000301)5.48432935
32ketone body metabolic process (GO:1902224)5.36254156
33regulation of Rab GTPase activity (GO:0032313)5.15794508
34positive regulation of Rab GTPase activity (GO:0032851)5.15794508
35chromatin silencing (GO:0006342)5.12474199
36regulation of inclusion body assembly (GO:0090083)4.99539769
37centriole replication (GO:0007099)4.99306702
38motile cilium assembly (GO:0044458)4.94195337
39regulation of cilium movement (GO:0003352)4.90987989
40single fertilization (GO:0007338)4.85141108
41germ cell development (GO:0007281)4.58406722
42regulation of transcription involved in cell fate commitment (GO:0060850)4.52429946
43coenzyme catabolic process (GO:0009109)4.45987353
44multicellular organismal reproductive process (GO:0048609)4.44887258
45centriole assembly (GO:0098534)4.44620334
46cell wall macromolecule catabolic process (GO:0016998)4.43722787
47cellular process involved in reproduction in multicellular organism (GO:0022412)4.38575823
48RNA destabilization (GO:0050779)4.31795422
49protein localization to Golgi apparatus (GO:0034067)4.23699667
50cilium or flagellum-dependent cell motility (GO:0001539)4.19350330
51cell wall macromolecule metabolic process (GO:0044036)4.18420208
52nucleus organization (GO:0006997)4.18294361
53negative regulation of Rho protein signal transduction (GO:0035024)4.11995445
54glycerol ether metabolic process (GO:0006662)4.10346274
55regulation of centriole replication (GO:0046599)4.07564783
56fertilization (GO:0009566)3.92435146
57ether metabolic process (GO:0018904)3.78445779
58epithelial cilium movement (GO:0003351)3.57612284
59seminiferous tubule development (GO:0072520)3.56775504
60protein-DNA complex disassembly (GO:0032986)3.55319044
61nucleosome disassembly (GO:0006337)3.55319044
62cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.54365713
63negative regulation of gene expression, epigenetic (GO:0045814)3.50581116
64organic cation transport (GO:0015695)3.45207263
65polyamine biosynthetic process (GO:0006596)3.44303366
66mesenchymal cell differentiation involved in renal system development (GO:2001012)3.43936886
67mesenchymal cell differentiation involved in kidney development (GO:0072161)3.43936886
68multicellular organismal movement (GO:0050879)3.42005216
69musculoskeletal movement (GO:0050881)3.42005216
70response to acidic pH (GO:0010447)3.38392826
71regulation of microtubule-based movement (GO:0060632)3.37305650
72peptidyl-threonine dephosphorylation (GO:0035970)3.34914896
73cranial nerve morphogenesis (GO:0021602)3.30947888
74regulation of somitogenesis (GO:0014807)3.30297933
75histone H3-K9 demethylation (GO:0033169)3.29399944
76cell differentiation involved in metanephros development (GO:0072202)3.28384965
77regulation of interleukin-13 production (GO:0032656)3.27840614
78cerebral cortex neuron differentiation (GO:0021895)3.27329591
79regulation of T-helper 2 cell differentiation (GO:0045628)3.24555478
80protein depolymerization (GO:0051261)3.22410870
81glomerular visceral epithelial cell development (GO:0072015)3.22185598
82DNA conformation change (GO:0071103)3.15970128
83cellular response to pH (GO:0071467)3.15650785
84cilium movement (GO:0003341)3.15125345
85glomerular epithelial cell development (GO:0072310)3.13907775
86NAD biosynthetic process (GO:0009435)3.09534820
87peptidyl-proline hydroxylation (GO:0019511)3.07155198
88cell recognition (GO:0008037)3.06619379
89homeostasis of number of cells within a tissue (GO:0048873)3.05847851
90membrane protein intracellular domain proteolysis (GO:0031293)3.04609386
91multicellular organismal development (GO:0007275)2.96163562
92tooth mineralization (GO:0034505)2.91799688
93negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.89848028
94metanephric mesenchyme development (GO:0072075)2.83775691
95negative regulation of histone methylation (GO:0031061)2.81799873
96acrosome reaction (GO:0007340)12.6797183
97sperm motility (GO:0030317)11.5809648
98fusion of sperm to egg plasma membrane (GO:0007342)11.5332099
99response to pheromone (GO:0019236)10.4563942
100chromosome condensation (GO:0030261)10.2530011

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.12321688
2MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human4.04623599
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.85869932
4TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.34482886
5POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.34482886
6ELF1_20517297_ChIP-Seq_JURKAT_Human2.33375710
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.19941610
8ERA_21632823_ChIP-Seq_H3396_Human2.13191705
9IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.11016588
10CBP_20019798_ChIP-Seq_JUKART_Human2.11016588
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09484062
12VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.08142607
13RBPJ_21746931_ChIP-Seq_IB4-LCL_Human2.00021350
14EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.98456355
15RAC3_21632823_ChIP-Seq_H3396_Human1.97748133
16EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.93524500
17NANOG_20526341_ChIP-Seq_ESCs_Human1.93076380
18CTBP1_25329375_ChIP-Seq_LNCAP_Human1.89827808
19CTCF_27219007_Chip-Seq_Bcells_Human1.89684518
20BCL6_27268052_Chip-Seq_Bcells_Human1.84174300
21E2F1_20622854_ChIP-Seq_HELA_Human1.82318020
22WDR5_24793694_ChIP-Seq_LNCAP_Human1.79861446
23SMC4_20622854_ChIP-Seq_HELA_Human1.78661351
24DROSHA_22980978_ChIP-Seq_HELA_Human1.74526971
25YY1_22570637_ChIP-Seq_MALME-3M_Human1.73137223
26TDRD3_21172665_ChIP-Seq_MCF-7_Human1.70157394
27P68_20966046_ChIP-Seq_HELA_Human1.69354155
28BCOR_27268052_Chip-Seq_Bcells_Human1.69055542
29FUS_26573619_Chip-Seq_HEK293_Human1.68138428
30EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67911507
31PHF8_20622854_ChIP-Seq_HELA_Human1.67161507
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.66852747
33CTCF_20526341_ChIP-Seq_ESCs_Human1.64536661
34UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.63524065
35LXR_22292898_ChIP-Seq_THP-1_Human1.62885896
36MYC_19829295_ChIP-Seq_ESCs_Human1.62775825
37TP63_22573176_ChIP-Seq_HFKS_Human1.61247167
38PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.56117627
39* TAF2_19829295_ChIP-Seq_ESCs_Human1.54904291
40AUTS2_25519132_ChIP-Seq_293T-REX_Human1.54723851
41OCT4_20526341_ChIP-Seq_ESCs_Human1.49930590
42ARNT_22903824_ChIP-Seq_MCF-7_Human1.49067446
43ER_23166858_ChIP-Seq_MCF-7_Human1.47236308
44TP53_18474530_ChIP-ChIP_U2OS_Human1.46026054
45P300_27268052_Chip-Seq_Bcells_Human1.45054577
46SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.44277281
47SMAD4_21741376_ChIP-Seq_EPCs_Human1.43337051
48ETV2_25802403_ChIP-Seq_MESCs_Mouse1.42806869
49HNFA_21074721_ChIP-Seq_CACO-2_Human1.39185579
50CBX2_22325352_ChIP-Seq_293T-Rex_Human1.34464624
51CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.34085266
52RBPJ_21746931_ChIP-Seq_IB4_Human1.33571404
53SUZ12_27294783_Chip-Seq_ESCs_Mouse1.33476181
54GATA3_21878914_ChIP-Seq_MCF-7_Human1.32413652
55AR_25329375_ChIP-Seq_VCAP_Human1.32260445
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32037080
57EZH2_22144423_ChIP-Seq_EOC_Human1.31785485
58SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30926652
59P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.30538786
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30185765
61SOX2_22085726_ChIP-Seq_NPCs_Mouse1.29622934
62ERG_20517297_ChIP-Seq_VCAP_Human1.26868829
63SA1_27219007_Chip-Seq_Bcells_Human1.26291677
64SMAD3_21741376_ChIP-Seq_ESCs_Human1.26284354
65ETV1_20927104_ChIP-Seq_GIST48_Human1.24559889
66CEBPB_22108803_ChIP-Seq_LS180_Human1.24253264
67P53_21459846_ChIP-Seq_SAOS-2_Human1.23331091
68KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.22695054
69RUNX_20019798_ChIP-Seq_JUKART_Human1.22207204
70TP63_19390658_ChIP-ChIP_HaCaT_Human1.18435718
71ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16997137
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16533025
73THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.16154618
74NFYB_21822215_ChIP-Seq_K562_Human1.15213530
75PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14718384
76RUNX1_26923725_Chip-Seq_HPCs_Mouse1.14454174
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.13679451
78TAF15_26573619_Chip-Seq_HEK293_Human1.13528852
79SMAD4_21741376_ChIP-Seq_HESCs_Human1.12812913
80TBL1_22424771_ChIP-Seq_293T_Human1.11740231
81EZH2_27294783_Chip-Seq_ESCs_Mouse1.11082913
82CSB_26484114_Chip-Seq_FIBROBLAST_Human1.11078240
83SMRT_27268052_Chip-Seq_Bcells_Human1.10980394
84EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10782596
85SA1_27219007_Chip-Seq_ERYTHROID_Human1.10483178
86GATA6_21074721_ChIP-Seq_CACO-2_Human1.09857977
87PHF8_20622853_ChIP-Seq_HELA_Human1.09164852
88P300_19829295_ChIP-Seq_ESCs_Human1.07153295
89TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05920592
90KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04990067
91HOXB7_26014856_ChIP-Seq_BT474_Human1.04524670
92RUNX1_27514584_Chip-Seq_MCF-7_Human1.02068240
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.99318482
94NFIB_24661679_ChIP-Seq_LUNG_Mouse0.99193012
95E2F1_17053090_ChIP-ChIP_MCF-7_Human0.98957844
96FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98534521
97KLF5_25053715_ChIP-Seq_YYC3_Human0.98376065
98NANOG_19829295_ChIP-Seq_ESCs_Human0.98245746
99SOX2_19829295_ChIP-Seq_ESCs_Human0.98245746
100JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98229207

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.90038225
2MP0003878_abnormal_ear_physiology4.90038225
3MP0005670_abnormal_white_adipose4.52642506
4MP0003698_abnormal_male_reproductive4.45721753
5MP0001348_abnormal_lacrimal_gland3.89204565
6MP0001929_abnormal_gametogenesis3.82276651
7MP0000678_abnormal_parathyroid_gland3.07312097
8MP0002161_abnormal_fertility/fecundity2.50813384
9MP0003011_delayed_dark_adaptation2.50039706
10MP0002132_abnormal_respiratory_system2.33017746
11MP0003718_maternal_effect2.29186737
12MP0005410_abnormal_fertilization12.7687350
13MP0002234_abnormal_pharynx_morphology1.96444469
14MP0002249_abnormal_larynx_morphology1.82547146
15MP0003646_muscle_fatigue1.82230029
16MP0005379_endocrine/exocrine_gland_phen1.81661166
17MP0005423_abnormal_somatic_nervous1.68284436
18MP0004510_myositis1.63447028
19MP0009053_abnormal_anal_canal1.63190674
20MP0002210_abnormal_sex_determination1.56749300
21MP0002282_abnormal_trachea_morphology1.50510074
22MP0001145_abnormal_male_reproductive1.32723828
23MP0001486_abnormal_startle_reflex1.29135934
24MP0000534_abnormal_ureter_morphology1.28853139
25MP0005310_abnormal_salivary_gland1.26019847
26MP0000653_abnormal_sex_gland1.24665074
27MP0001485_abnormal_pinna_reflex1.23043447
28MP0002127_abnormal_cardiovascular_syste1.20255667
29MP0005248_abnormal_Harderian_gland1.19801649
30MP0002735_abnormal_chemical_nociception1.17254019
31MP0001765_abnormal_ion_homeostasis1.16564225
32MP0001968_abnormal_touch/_nociception1.12146930
33MP0004742_abnormal_vestibular_system1.11770500
34MP0000681_abnormal_thyroid_gland1.08162840
35MP0004859_abnormal_synaptic_plasticity1.07070917
36MP0005395_other_phenotype1.06345783
37MP0002138_abnormal_hepatobiliary_system1.05272647
38MP0001963_abnormal_hearing_physiology0.97716977
39MP0000049_abnormal_middle_ear0.95512369
40MP0000026_abnormal_inner_ear0.93480936
41MP0002822_catalepsy0.92652032
42MP0003879_abnormal_hair_cell0.87770365
43MP0005367_renal/urinary_system_phenotyp0.84088257
44MP0000516_abnormal_urinary_system0.84088257
45MP0001879_abnormal_lymphatic_vessel0.80414516
46MP0002229_neurodegeneration0.79991524
47MP0000955_abnormal_spinal_cord0.79886338
48MP0005623_abnormal_meninges_morphology0.79166528
49MP0005451_abnormal_body_composition0.78688759
50MP0002733_abnormal_thermal_nociception0.74751478
51MP0005083_abnormal_biliary_tract0.74708341
52MP0004085_abnormal_heartbeat0.70715236
53MP0005666_abnormal_adipose_tissue0.68576348
54MP0009115_abnormal_fat_cell0.68263399
55MP0005375_adipose_tissue_phenotype0.66958161
56MP0004233_abnormal_muscle_weight0.65794179
57MP0000003_abnormal_adipose_tissue0.65750152
58MP0005636_abnormal_mineral_homeostasis0.64913310
59MP0002067_abnormal_sensory_capabilities0.63692812
60MP0009697_abnormal_copulation0.63569771
61MP0008569_lethality_at_weaning0.63237163
62MP0005551_abnormal_eye_electrophysiolog0.58703018
63MP0004484_altered_response_of0.58446121
64MP0003077_abnormal_cell_cycle0.55719832
65MP0002557_abnormal_social/conspecific_i0.55038319
66MP0001905_abnormal_dopamine_level0.54724504
67MP0001666_abnormal_nutrient_absorption0.53740229
68MP0008877_abnormal_DNA_methylation0.53311674
69MP0001970_abnormal_pain_threshold0.48010642
70MP0005167_abnormal_blood-brain_barrier0.47616235
71MP0003119_abnormal_digestive_system0.46714525
72MP0000249_abnormal_blood_vessel0.46634853
73MP0005253_abnormal_eye_physiology0.45964465
74MP0002653_abnormal_ependyma_morphology0.45854012
75MP0006292_abnormal_olfactory_placode0.45695137
76MP0002572_abnormal_emotion/affect_behav0.44676145
77MP0000613_abnormal_salivary_gland0.44066315
78MP0003137_abnormal_impulse_conducting0.43187734
79MP0004036_abnormal_muscle_relaxation0.41889739
80MP0003699_abnormal_female_reproductive0.41765747
81MP0008995_early_reproductive_senescence0.41373305
82MP0008961_abnormal_basal_metabolism0.41354923
83MP0003936_abnormal_reproductive_system0.41157859
84MP0005535_abnormal_body_temperature0.40641875
85MP0000566_synostosis0.39014204
86MP0000470_abnormal_stomach_morphology0.38936010
87MP0000467_abnormal_esophagus_morphology0.38511619
88MP0002272_abnormal_nervous_system0.37754958
89MP0002734_abnormal_mechanical_nocicepti0.35929943
90MP0003942_abnormal_urinary_system0.35853775
91MP0005408_hypopigmentation0.35178709
92MP0003091_abnormal_cell_migration0.34497091
93MP0003880_abnormal_central_pattern0.33758103
94MP0001440_abnormal_grooming_behavior0.32388929
95MP0002928_abnormal_bile_duct0.30377923
96MP0009745_abnormal_behavioral_response0.30141885
97MP0005166_decreased_susceptibility_to0.29776748
98MP0003172_abnormal_lysosome_physiology0.29733175
99MP0005084_abnormal_gallbladder_morpholo0.29570612
100MP0005647_abnormal_sex_gland0.28844217

Predicted human phenotypes

RankGene SetZ-score
1Severe visual impairment (HP:0001141)9.02509537
2Dynein arm defect of respiratory motile cilia (HP:0012255)5.92192953
3Absent/shortened dynein arms (HP:0200106)5.92192953
4Asymmetric septal hypertrophy (HP:0001670)5.33489730
5Attenuation of retinal blood vessels (HP:0007843)5.27247216
6Bony spicule pigmentary retinopathy (HP:0007737)5.26267742
7Resting tremor (HP:0002322)4.71336614
8Bell-shaped thorax (HP:0001591)4.64451954
9Abnormal ciliary motility (HP:0012262)4.55806968
10Abnormal respiratory motile cilium physiology (HP:0012261)4.46459833
11Abnormal rod and cone electroretinograms (HP:0008323)4.37340173
12Nasal polyposis (HP:0100582)4.36647306
13Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.30391544
14Abnormal respiratory epithelium morphology (HP:0012253)4.29560683
15Abnormal respiratory motile cilium morphology (HP:0005938)4.29560683
16Hypoplastic ischia (HP:0003175)4.28679674
17Infertility (HP:0000789)4.19185923
18Tubulointerstitial nephritis (HP:0001970)4.08598131
19Male infertility (HP:0003251)4.06175350
20Hyperkalemia (HP:0002153)4.01817277
21Potter facies (HP:0002009)4.00753735
22Facial shape deformation (HP:0011334)4.00753735
23Abnormality of macular pigmentation (HP:0008002)3.93256367
24Enlarged epiphyses (HP:0010580)3.89621140
25Azoospermia (HP:0000027)3.82134027
26Abnormality of the ischium (HP:0003174)3.81790642
27Unilateral renal agenesis (HP:0000122)3.75171870
28Aplasia/Hypoplasia of the earlobes (HP:0009906)3.71263802
29Abnormal spermatogenesis (HP:0008669)3.67440022
30Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.61437507
31Chronic hepatic failure (HP:0100626)3.56582639
32Abnormality of the nasal mucosa (HP:0000433)3.55822295
33Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.46050784
34Cone-rod dystrophy (HP:0000548)3.28864343
35Double outlet right ventricle (HP:0001719)3.22115101
36Congenital malformation of the right heart (HP:0011723)3.22115101
37Impulsivity (HP:0100710)3.10980255
38Hypoplasia of the thymus (HP:0000778)2.99525596
39Abnormality of the aortic arch (HP:0012303)2.99005891
40Renal dysplasia (HP:0000110)2.84902581
41Postural instability (HP:0002172)2.82890289
42Generalized aminoaciduria (HP:0002909)2.78770522
43Abnormal urine output (HP:0012590)2.76957676
44Progressive sensorineural hearing impairment (HP:0000408)2.75781627
45Rhinitis (HP:0012384)2.54641383
46Stage 5 chronic kidney disease (HP:0003774)2.53606834
47Hypoalphalipoproteinemia (HP:0003233)2.49537182
48Abnormality of the parathyroid morphology (HP:0011766)2.48288081
49Absent epiphyses (HP:0010577)2.46590222
50Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.46590222
51Ventricular tachycardia (HP:0004756)2.46540396
52Hyperthyroidism (HP:0000836)2.43806300
53Abnormality of potassium homeostasis (HP:0011042)2.43288691
54Abnormality of the costochondral junction (HP:0000919)2.42042963
55Flattened epiphyses (HP:0003071)2.39256694
56Epiphyseal dysplasia (HP:0002656)2.38858876
57Abnormality of renal excretion (HP:0011036)2.37944671
58Nephronophthisis (HP:0000090)2.34540610
59Amelogenesis imperfecta (HP:0000705)2.33134490
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.31258577
61Abnormality of dental color (HP:0011073)2.24658261
62Truncal obesity (HP:0001956)2.20944203
63Tetany (HP:0001281)2.19715007
64Spastic paraparesis (HP:0002313)2.18767317
65Abnormality of the epiphysis of the femoral head (HP:0010574)2.18715591
66Progressive cerebellar ataxia (HP:0002073)2.18046126
67Polyuria (HP:0000103)2.16512929
68Abnormal drinking behavior (HP:0030082)2.16187335
69Polydipsia (HP:0001959)2.16187335
70Hypoparathyroidism (HP:0000829)2.15078363
71Hyponatremia (HP:0002902)2.12646632
72Insulin-resistant diabetes mellitus (HP:0000831)2.11722012
73Atelectasis (HP:0100750)2.09810866
74Abnormality of the pubic bones (HP:0003172)2.09282251
75Abnormality of femoral epiphyses (HP:0006499)2.04663874
76Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.04663874
77Abnormal ventriculo-arterial connection (HP:0011563)2.02357707
78Transposition of the great arteries (HP:0001669)2.02357707
79Abnormal connection of the cardiac segments (HP:0011545)2.02357707
80Sensory axonal neuropathy (HP:0003390)2.02299758
81Osteomalacia (HP:0002749)2.02296580
82Portal hypertension (HP:0001409)2.01615923
83Focal segmental glomerulosclerosis (HP:0000097)1.97743752
84Abnormality of the renal medulla (HP:0100957)1.96248508
85Renovascular hypertension (HP:0100817)1.95644544
86Bowel incontinence (HP:0002607)1.95236203
87Bronchiectasis (HP:0002110)1.93873790
88Abnormality of the femoral head (HP:0003368)1.93704705
89Widely patent fontanelles and sutures (HP:0004492)1.92939700
90Flat capital femoral epiphysis (HP:0003370)1.92532670
91Bradycardia (HP:0001662)1.91044932
92Recurrent corneal erosions (HP:0000495)1.90280137
93Tubulointerstitial abnormality (HP:0001969)1.89020645
94Decreased central vision (HP:0007663)1.86017359
95Short ribs (HP:0000773)1.84829863
96Abnormality of the hepatic vasculature (HP:0006707)1.83090116
97Amblyopia (HP:0000646)1.82847977
98Menstrual irregularities (HP:0000858)1.82316407
99Abnormal large intestine physiology (HP:0012700)1.82235922
100Hypophosphatemic rickets (HP:0004912)1.82200786

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK48.13567935
2TESK16.92593103
3DDR25.51792752
4MAP4K24.07106293
5INSRR3.82756148
6STK383.23114509
7PLK22.94896883
8BRD42.72938005
9PNCK2.50807438
10MAPK152.38691082
11PRKD32.16526293
12STK38L2.15192428
13MST1R2.10273181
14CAMK1G1.98805074
15WNK11.91823409
16PDPK11.62755755
17PIK3CG1.57173612
18CDK71.46283041
19PDK11.44405338
20DYRK1B1.30315986
21CDK121.24943174
22KSR21.22820020
23MAP3K91.19804050
24LATS21.14227009
25PTK2B1.11240645
26NEK61.06638445
27UHMK10.86259795
28BRAF0.75380116
29PRKG20.73973552
30CAMK1D0.73284474
31MAP3K20.72033948
32RPS6KA20.70405382
33MAP3K80.70024211
34PRKAA20.69887639
35MAP3K110.69653750
36AKT30.69053061
37MAP2K20.67927933
38PRKG10.61625647
39RPS6KA10.60550596
40ROCK10.55890800
41LATS10.55448768
42WNK40.54897908
43CDK40.52714878
44CAMK10.51331309
45MET0.49614556
46MUSK0.47954743
47SIK20.47909892
48ARAF0.47807803
49TESK20.46136667
50CDK30.44830341
51GSK3B0.43340871
52CDK20.41574140
53STK390.40379186
54CDK10.40051242
55MAPK10.38191270
56MTOR0.37123231
57MAP3K10.36379411
58RPS6KL10.35696554
59RPS6KC10.35696554
60BRSK10.33803768
61BMPR1B0.33679637
62CAMK40.33514024
63MAPK80.33126208
64RPS6KA60.32181388
65TYRO30.31969591
66CHEK10.30413659
67PRKCG0.29985038
68MARK10.28524394
69SGK4940.28054027
70SGK2230.28054027
71PRKCZ0.27639998
72NTRK30.22455790
73MAPK140.21698010
74ABL20.21387971
75MAPK100.19866922
76SGK10.19307571
77PRKCB0.18030020
78MAPK110.17135475
79FER0.17115252
80MARK20.16238281
81AKT10.15584027
82TIE10.15246278
83BLK0.13661285
84PKN10.12605182
85IKBKB0.09717453
86DYRK30.09116447
87OXSR10.08091859
88CHUK0.06348177
89PRKACB0.05852123
90AURKA0.05760732
91PRKACA0.05446494
92MAPK90.05445278
93CAMK2A0.05154334
94MAP2K10.04591443
95PINK10.04539890
96PAK20.04383493
97MAP3K70.04317928
98ROCK20.03995736
99MAP3K40.03351885
100PRKAA10.02811190

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.83709606
2Fatty acid biosynthesis_Homo sapiens_hsa000615.62464974
3Olfactory transduction_Homo sapiens_hsa047403.68434229
4Butanoate metabolism_Homo sapiens_hsa006502.85673704
5Allograft rejection_Homo sapiens_hsa053302.28214557
6Autoimmune thyroid disease_Homo sapiens_hsa053202.22436420
7Type I diabetes mellitus_Homo sapiens_hsa049402.17900529
8Graft-versus-host disease_Homo sapiens_hsa053322.08795388
9Antigen processing and presentation_Homo sapiens_hsa046122.03357247
10Glycerophospholipid metabolism_Homo sapiens_hsa005641.92728028
11Phenylalanine metabolism_Homo sapiens_hsa003601.84869251
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.67459721
13Viral myocarditis_Homo sapiens_hsa054161.67449868
14Taste transduction_Homo sapiens_hsa047421.64933160
15Dorso-ventral axis formation_Homo sapiens_hsa043201.63678283
16Type II diabetes mellitus_Homo sapiens_hsa049301.52326797
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49545936
18Arginine and proline metabolism_Homo sapiens_hsa003301.45879071
19Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43876738
20Fatty acid degradation_Homo sapiens_hsa000711.42699410
21RNA transport_Homo sapiens_hsa030131.37469750
22Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.37202880
23Fatty acid metabolism_Homo sapiens_hsa012121.30306614
24Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.29463026
25Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.26690467
26Endocytosis_Homo sapiens_hsa041441.23800846
27Protein digestion and absorption_Homo sapiens_hsa049741.06661635
28Arginine biosynthesis_Homo sapiens_hsa002200.99824672
29Adipocytokine signaling pathway_Homo sapiens_hsa049200.98888511
30Cardiac muscle contraction_Homo sapiens_hsa042600.97921345
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97847942
32Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96299377
33Salivary secretion_Homo sapiens_hsa049700.93858739
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.87988269
35Influenza A_Homo sapiens_hsa051640.87630549
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84771970
37Phototransduction_Homo sapiens_hsa047440.84503773
38Oocyte meiosis_Homo sapiens_hsa041140.83919680
39Tyrosine metabolism_Homo sapiens_hsa003500.83256273
40Inositol phosphate metabolism_Homo sapiens_hsa005620.77491931
41PPAR signaling pathway_Homo sapiens_hsa033200.74988797
42cAMP signaling pathway_Homo sapiens_hsa040240.74756553
43Renin-angiotensin system_Homo sapiens_hsa046140.74180234
44Fat digestion and absorption_Homo sapiens_hsa049750.72929894
45Hedgehog signaling pathway_Homo sapiens_hsa043400.70344810
46Calcium signaling pathway_Homo sapiens_hsa040200.69904544
47Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66717677
48Estrogen signaling pathway_Homo sapiens_hsa049150.66670041
49Morphine addiction_Homo sapiens_hsa050320.64799034
50Synaptic vesicle cycle_Homo sapiens_hsa047210.63591795
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.58164847
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55786360
53Retinol metabolism_Homo sapiens_hsa008300.54581831
54Purine metabolism_Homo sapiens_hsa002300.54012046
55Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51319827
56ABC transporters_Homo sapiens_hsa020100.50099925
57Circadian entrainment_Homo sapiens_hsa047130.50039163
58Glycerolipid metabolism_Homo sapiens_hsa005610.48515484
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45657967
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.43868512
61MAPK signaling pathway_Homo sapiens_hsa040100.42629622
62Nicotine addiction_Homo sapiens_hsa050330.41515424
63Selenocompound metabolism_Homo sapiens_hsa004500.41452719
64VEGF signaling pathway_Homo sapiens_hsa043700.41118011
65Acute myeloid leukemia_Homo sapiens_hsa052210.40855705
66Tight junction_Homo sapiens_hsa045300.39676371
67Bile secretion_Homo sapiens_hsa049760.39372240
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.38676781
69Renin secretion_Homo sapiens_hsa049240.38309105
70Maturity onset diabetes of the young_Homo sapiens_hsa049500.38081297
71Viral carcinogenesis_Homo sapiens_hsa052030.37446491
72Insulin secretion_Homo sapiens_hsa049110.34837941
73Gastric acid secretion_Homo sapiens_hsa049710.34765417
74Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33209877
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33127443
76Glutamatergic synapse_Homo sapiens_hsa047240.32698427
77mRNA surveillance pathway_Homo sapiens_hsa030150.31353491
78Basal transcription factors_Homo sapiens_hsa030220.29381450
79Biosynthesis of amino acids_Homo sapiens_hsa012300.27940174
80ECM-receptor interaction_Homo sapiens_hsa045120.27624505
81Herpes simplex infection_Homo sapiens_hsa051680.26476961
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.26387841
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26067244
84Epstein-Barr virus infection_Homo sapiens_hsa051690.24272182
85Legionellosis_Homo sapiens_hsa051340.22087136
86Vitamin B6 metabolism_Homo sapiens_hsa007500.19894315
87Huntingtons disease_Homo sapiens_hsa050160.19528555
88Cholinergic synapse_Homo sapiens_hsa047250.19343449
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.17944259
90Pancreatic secretion_Homo sapiens_hsa049720.17828946
91Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.17705556
92Toxoplasmosis_Homo sapiens_hsa051450.17331713
93Serotonergic synapse_Homo sapiens_hsa047260.15981392
94Prolactin signaling pathway_Homo sapiens_hsa049170.15509987
95Fanconi anemia pathway_Homo sapiens_hsa034600.14530571
96Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.13787500
97Adherens junction_Homo sapiens_hsa045200.13611538
98Oxytocin signaling pathway_Homo sapiens_hsa049210.13262857
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.13189240
100Metabolic pathways_Homo sapiens_hsa011000.13176629

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »