C19ORF24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1GDP-mannose metabolic process (GO:0019673)4.92454222
2ribosomal small subunit biogenesis (GO:0042274)4.67039822
3deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.66504626
4negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.34562899
5protein maturation by protein folding (GO:0022417)4.17741071
6pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.78452335
7regulation of mitochondrial translation (GO:0070129)3.75040916
8purine deoxyribonucleotide catabolic process (GO:0009155)3.70615641
9viral transcription (GO:0019083)3.59997743
10deoxyribonucleotide catabolic process (GO:0009264)3.54125980
11NIK/NF-kappaB signaling (GO:0038061)3.48041709
12deoxyribose phosphate catabolic process (GO:0046386)3.43242165
13translational termination (GO:0006415)3.27255256
14nucleotide salvage (GO:0043173)3.18324471
15translational elongation (GO:0006414)3.17247821
16maturation of SSU-rRNA (GO:0030490)3.15036017
17base-excision repair, AP site formation (GO:0006285)3.14706966
18purine nucleotide salvage (GO:0032261)3.12035948
19pyrimidine nucleotide catabolic process (GO:0006244)3.09506752
20pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.05879357
21pseudouridine synthesis (GO:0001522)3.05475237
22pentose metabolic process (GO:0019321)3.05443683
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.03460921
24mitotic nuclear envelope reassembly (GO:0007084)3.01295038
25nuclear envelope reassembly (GO:0031468)3.01295038
26ribosomal small subunit assembly (GO:0000028)3.01206055
27negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.00832518
28guanosine-containing compound biosynthetic process (GO:1901070)2.99720509
29protein targeting to ER (GO:0045047)2.97944780
30negative regulation of B cell apoptotic process (GO:0002903)2.96982013
31viral life cycle (GO:0019058)2.92955281
32protein localization to endoplasmic reticulum (GO:0070972)2.92739649
33cotranslational protein targeting to membrane (GO:0006613)2.91322306
34UV protection (GO:0009650)2.89602621
35pyrimidine nucleoside salvage (GO:0043097)2.86226508
36pyrimidine-containing compound salvage (GO:0008655)2.86226508
37proteasome assembly (GO:0043248)2.85964398
38nucleoside salvage (GO:0043174)2.83673318
39protein targeting to mitochondrion (GO:0006626)2.81789460
40rRNA modification (GO:0000154)2.81075498
41positive regulation of T cell apoptotic process (GO:0070234)2.79870864
42regulation of mammary gland epithelial cell proliferation (GO:0033599)2.79386055
43proline biosynthetic process (GO:0006561)2.79146681
44antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.78246393
45establishment of protein localization to endoplasmic reticulum (GO:0072599)2.77026611
46negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.75501977
47ribonucleoprotein complex biogenesis (GO:0022613)2.74301295
482-deoxyribonucleotide metabolic process (GO:0009394)2.73908757
49mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.72828291
50COPI coating of Golgi vesicle (GO:0048205)2.70272825
51Golgi transport vesicle coating (GO:0048200)2.70272825
52deoxyribose phosphate biosynthetic process (GO:0046385)2.70001186
532-deoxyribonucleotide biosynthetic process (GO:0009265)2.70001186
54nucleobase-containing small molecule interconversion (GO:0015949)2.69180065
55establishment of protein localization to mitochondrion (GO:0072655)2.68703381
56antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.67515496
57negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.66446836
58iron-sulfur cluster assembly (GO:0016226)2.65450391
59metallo-sulfur cluster assembly (GO:0031163)2.65450391
60negative regulation of myeloid cell apoptotic process (GO:0033033)2.65368381
61DNA deamination (GO:0045006)2.63612793
62UTP biosynthetic process (GO:0006228)2.63031286
63deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.61658689
64deoxyribose phosphate metabolic process (GO:0019692)2.61348246
65transcription from mitochondrial promoter (GO:0006390)2.61066658
66chaperone-mediated protein transport (GO:0072321)2.60796072
67ATP synthesis coupled proton transport (GO:0015986)2.60342429
68energy coupled proton transport, down electrochemical gradient (GO:0015985)2.60342429
69protein complex biogenesis (GO:0070271)2.58932324
70GTP biosynthetic process (GO:0006183)2.58289747
71peptidyl-arginine omega-N-methylation (GO:0035247)2.58065715
72nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.57907174
73negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.57023104
74negative regulation of ligase activity (GO:0051352)2.57023104
75oxidative phosphorylation (GO:0006119)2.56852003
76Arp2/3 complex-mediated actin nucleation (GO:0034314)2.56451159
77cellular protein complex disassembly (GO:0043624)2.55241713
78amino sugar catabolic process (GO:0046348)2.54562036
79cellular component biogenesis (GO:0044085)2.52758523
80translation (GO:0006412)2.52652449
81positive regulation of lymphocyte apoptotic process (GO:0070230)2.52504394
82pinocytosis (GO:0006907)2.52213947
83termination of RNA polymerase III transcription (GO:0006386)2.48998029
84transcription elongation from RNA polymerase III promoter (GO:0006385)2.48998029
85folic acid metabolic process (GO:0046655)2.48472535
86purine deoxyribonucleotide metabolic process (GO:0009151)2.47932644
87modulation by virus of host process (GO:0019054)2.46934539
88positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.45654080
89tRNA methylation (GO:0030488)2.43820236
90ribosomal large subunit biogenesis (GO:0042273)2.42871297
91respiratory electron transport chain (GO:0022904)2.41722374
92rRNA transcription (GO:0009303)2.40322566
93protein retention in ER lumen (GO:0006621)2.40264465
94regulation of mitochondrial membrane potential (GO:0051881)2.40006102
95chaperone mediated protein folding requiring cofactor (GO:0051085)2.39947366
96regulation of translational termination (GO:0006449)2.39433687
97regulation of superoxide anion generation (GO:0032928)2.39064442
98negative regulation of cell size (GO:0045792)2.38755946
99pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.37929716
100translational initiation (GO:0006413)2.37873230

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.07002848
2* VDR_21846776_ChIP-Seq_THP-1_Human2.73752740
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.73277600
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.57292198
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50981762
6MYC_18555785_ChIP-Seq_MESCs_Mouse2.31996062
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.24545798
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.23576944
9TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.22694592
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.20095145
11* LXR_22292898_ChIP-Seq_THP-1_Human2.10493015
12MYC_22102868_ChIP-Seq_BL_Human2.08813327
13ELF1_17652178_ChIP-ChIP_JURKAT_Human1.98909828
14ETS1_20019798_ChIP-Seq_JURKAT_Human1.95652118
15* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.90106319
16XRN2_22483619_ChIP-Seq_HELA_Human1.89959926
17CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.87479586
18DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.85591221
19ELK3_25401928_ChIP-Seq_HUVEC_Human1.83389094
20THAP11_20581084_ChIP-Seq_MESCs_Mouse1.73162046
21TET1_21451524_ChIP-Seq_MESCs_Mouse1.71491757
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.69364468
23CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.68080147
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.65428195
25MYC_19030024_ChIP-ChIP_MESCs_Mouse1.63626016
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62105659
27TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.61927244
28E2F7_22180533_ChIP-Seq_HELA_Human1.60971083
29GABP_19822575_ChIP-Seq_HepG2_Human1.60929300
30SRY_22984422_ChIP-ChIP_TESTIS_Rat1.60679756
31P68_20966046_ChIP-Seq_HELA_Human1.60196838
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.57653263
33ZNF263_19887448_ChIP-Seq_K562_Human1.57481913
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55844067
35* DCP1A_22483619_ChIP-Seq_HELA_Human1.55294545
36SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.55221954
37ELF1_20517297_ChIP-Seq_JURKAT_Human1.54290366
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.53412802
39MYC_19079543_ChIP-ChIP_MESCs_Mouse1.52569715
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.51489879
41RACK7_27058665_Chip-Seq_MCF-7_Human1.50786945
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.50499780
43MAF_26560356_Chip-Seq_TH2_Human1.50054115
44CREB1_15753290_ChIP-ChIP_HEK293T_Human1.49942123
45BCL6_27268052_Chip-Seq_Bcells_Human1.47520781
46GABP_17652178_ChIP-ChIP_JURKAT_Human1.44271202
47* VDR_24763502_ChIP-Seq_THP-1_Human1.41437372
48MAF_26560356_Chip-Seq_TH1_Human1.40325240
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.39982253
50NELFA_20434984_ChIP-Seq_ESCs_Mouse1.39682020
51CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.38928770
52BCOR_27268052_Chip-Seq_Bcells_Human1.38797096
53KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.37733893
54RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.37206964
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.35661660
56UTX_26944678_Chip-Seq_JUKART_Human1.33647772
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.32516750
58SA1_27219007_Chip-Seq_ERYTHROID_Human1.29914723
59CIITA_25753668_ChIP-Seq_RAJI_Human1.29467628
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25732949
61SRF_21415370_ChIP-Seq_HL-1_Mouse1.24711785
62THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.23886307
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23816904
64CTCF_26484167_Chip-Seq_Bcells_Mouse1.23620121
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.23449233
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23334498
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.23187537
68BP1_19119308_ChIP-ChIP_Hs578T_Human1.23058250
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.22926261
70PU.1_20513432_ChIP-Seq_Bcells_Mouse1.21835868
71CTCF_18555785_ChIP-Seq_MESCs_Mouse1.21023536
72KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19741001
73SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17702900
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17084019
75STAT4_19710469_ChIP-ChIP_TH1__Mouse1.16810809
76EST1_17652178_ChIP-ChIP_JURKAT_Human1.15702095
77FOXP1_21924763_ChIP-Seq_HESCs_Human1.15550846
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.15344054
79CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.14219451
80FOXP3_21729870_ChIP-Seq_TREG_Human1.13809145
81ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13764766
82IRF8_22096565_ChIP-ChIP_GC-B_Human1.13750992
83* KDM2B_26808549_Chip-Seq_DND41_Human1.13177793
84SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.13108175
85HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.12188266
86* PHF8_20622854_ChIP-Seq_HELA_Human1.11054012
87* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10960214
88ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10639561
89E2F1_20622854_ChIP-Seq_HELA_Human1.10459792
90PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10052963
91TTF2_22483619_ChIP-Seq_HELA_Human1.09965773
92KDM5A_27292631_Chip-Seq_BREAST_Human1.09631537
93YY1_22570637_ChIP-Seq_MALME-3M_Human1.09594934
94* TFEB_21752829_ChIP-Seq_HELA_Human1.09310736
95CTCF_21964334_Chip-Seq_Bcells_Human1.08809902
96TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08445177
97MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.08257219
98KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07966418
99SPI1_23547873_ChIP-Seq_NB4_Human1.07883213
100STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06838387

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology3.87038334
2MP0003806_abnormal_nucleotide_metabolis3.46725495
3MP0005451_abnormal_body_composition3.37482496
4MP0009333_abnormal_splenocyte_physiolog3.11481757
5MP0009840_abnormal_foam_cell2.55402336
6MP0003436_decreased_susceptibility_to2.53403996
7MP0008260_abnormal_autophagy2.19073024
8MP0005671_abnormal_response_to2.12272739
9MP0002148_abnormal_hypersensitivity_rea2.09435077
10MP0004185_abnormal_adipocyte_glucose2.03341226
11MP0005025_abnormal_response_to2.01456471
12MP0001835_abnormal_antigen_presentation1.99800941
13MP0003191_abnormal_cellular_cholesterol1.97835084
14MP0003763_abnormal_thymus_physiology1.94042469
15MP0000685_abnormal_immune_system1.91023949
16MP0003693_abnormal_embryo_hatching1.86268380
17MP0005000_abnormal_immune_tolerance1.82767668
18MP0001853_heart_inflammation1.81962421
19MP0009785_altered_susceptibility_to1.81555093
20MP0000858_altered_metastatic_potential1.75675151
21MP0003303_peritoneal_inflammation1.72967450
22MP0002723_abnormal_immune_serum1.71054981
23MP0001873_stomach_inflammation1.70560426
24MP0003186_abnormal_redox_activity1.68411664
25MP0006036_abnormal_mitochondrial_physio1.67645415
26MP0002420_abnormal_adaptive_immunity1.66630015
27MP0001819_abnormal_immune_cell1.66617491
28MP0002419_abnormal_innate_immunity1.60325330
29MP0002452_abnormal_antigen_presenting1.60278409
30MP0001661_extended_life_span1.58681603
31MP0003111_abnormal_nucleus_morphology1.58274709
32MP0005387_immune_system_phenotype1.57253462
33MP0001790_abnormal_immune_system1.57253462
34MP0001800_abnormal_humoral_immune1.56956802
35MP0000490_abnormal_crypts_of1.56337624
36MP0005464_abnormal_platelet_physiology1.55606491
37MP0003786_premature_aging1.54383903
38MP0006082_CNS_inflammation1.49691408
39MP0002398_abnormal_bone_marrow1.48985996
40MP0002877_abnormal_melanocyte_morpholog1.48219078
41MP0000343_altered_response_to1.43755719
42MP0000716_abnormal_immune_system1.42559065
43MP0005670_abnormal_white_adipose1.42103129
44MP0002429_abnormal_blood_cell1.40919231
45MP0003172_abnormal_lysosome_physiology1.37893420
46MP0002722_abnormal_immune_system1.37801350
47MP0009278_abnormal_bone_marrow1.34745046
48MP0000678_abnormal_parathyroid_gland1.34735363
49MP0005501_abnormal_skin_physiology1.32904223
50MP0009379_abnormal_foot_pigmentation1.31195293
51MP0003075_altered_response_to1.30992462
52MP0001845_abnormal_inflammatory_respons1.30971070
53MP0004947_skin_inflammation1.30097703
54MP0010155_abnormal_intestine_physiology1.26795765
55MP0008469_abnormal_protein_level1.26562660
56MP0000689_abnormal_spleen_morphology1.26416411
57MP0003077_abnormal_cell_cycle1.24850353
58MP0000703_abnormal_thymus_morphology1.24624709
59MP0002405_respiratory_system_inflammati1.22111869
60MP0003453_abnormal_keratinocyte_physiol1.20232932
61MP0005666_abnormal_adipose_tissue1.16545528
62MP0004957_abnormal_blastocyst_morpholog1.16484172
63MP0005360_urolithiasis1.15735182
64MP0002132_abnormal_respiratory_system1.12557020
65MP0002019_abnormal_tumor_incidence1.11159464
66MP0004858_abnormal_nervous_system1.10760099
67MP0006035_abnormal_mitochondrial_morpho1.07668694
68MP0000358_abnormal_cell_content/1.04954980
69MP0000313_abnormal_cell_death1.04914162
70MP0001533_abnormal_skeleton_physiology1.04620721
71MP0005584_abnormal_enzyme/coenzyme_acti1.03147204
72MP0000750_abnormal_muscle_regeneration1.00879416
73MP0003448_altered_tumor_morphology0.95131463
74MP0001764_abnormal_homeostasis0.94841917
75MP0003705_abnormal_hypodermis_morpholog0.94711509
76MP0005310_abnormal_salivary_gland0.93920453
77MP0005330_cardiomyopathy0.93718555
78MP0002796_impaired_skin_barrier0.93449531
79MP0005083_abnormal_biliary_tract0.93236668
80MP0002139_abnormal_hepatobiliary_system0.92939816
81MP0004510_myositis0.91197551
82MP0008007_abnormal_cellular_replicative0.90380187
83MP0001545_abnormal_hematopoietic_system0.87371512
84MP0005397_hematopoietic_system_phenotyp0.87371512
85MP0009764_decreased_sensitivity_to0.84515195
86MP0001542_abnormal_bone_strength0.84489330
87MP0005166_decreased_susceptibility_to0.83637788
88MP0009643_abnormal_urine_homeostasis0.83532144
89MP0003866_abnormal_defecation0.82672858
90MP0005375_adipose_tissue_phenotype0.82120336
91MP0005165_increased_susceptibility_to0.79784539
92MP0000681_abnormal_thyroid_gland0.79385530
93MP0005319_abnormal_enzyme/_coenzyme0.78888257
94MP0005076_abnormal_cell_differentiation0.78323023
95MP0001663_abnormal_digestive_system0.76119524
96MP0000609_abnormal_liver_physiology0.75447190
97MP0008058_abnormal_DNA_repair0.75092458
98MP0002396_abnormal_hematopoietic_system0.74893862
99MP0001881_abnormal_mammary_gland0.74705892
100MP0009931_abnormal_skin_appearance0.73135799

Predicted human phenotypes

RankGene SetZ-score
1Testicular atrophy (HP:0000029)3.61503384
2Abnormality of liposaccharide metabolism (HP:0010968)3.37072575
3Abnormality of glycosphingolipid metabolism (HP:0004343)3.37072575
4Abnormality of glycolipid metabolism (HP:0010969)3.37072575
5Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.36315159
6Microvesicular hepatic steatosis (HP:0001414)3.30652168
7Increased muscle lipid content (HP:0009058)3.18793861
8Increased intramyocellular lipid droplets (HP:0012240)3.14571321
9Vertebral compression fractures (HP:0002953)3.12135790
10Mitochondrial inheritance (HP:0001427)3.07096813
11Hepatocellular necrosis (HP:0001404)3.00894327
12Abnormal mitochondria in muscle tissue (HP:0008316)2.99621686
13Ragged-red muscle fibers (HP:0003200)2.85662152
14Increased neuronal autofluorescent lipopigment (HP:0002074)2.75222124
15Increased cerebral lipofuscin (HP:0011813)2.74698882
16Acute necrotizing encephalopathy (HP:0006965)2.72054970
17Hypertensive crisis (HP:0100735)2.71759572
18Petechiae (HP:0000967)2.67744155
19Abnormal number of erythroid precursors (HP:0012131)2.67314302
20Renal Fanconi syndrome (HP:0001994)2.66601909
21Progressive muscle weakness (HP:0003323)2.63853483
22Dysostosis multiplex (HP:0000943)2.63403790
23Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.63211816
24Decreased activity of mitochondrial respiratory chain (HP:0008972)2.63211816
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.61937198
26Rough bone trabeculation (HP:0100670)2.58809184
27Abnormality of cells of the erythroid lineage (HP:0012130)2.58746900
28Hepatic necrosis (HP:0002605)2.58581280
29Chronic obstructive pulmonary disease (HP:0006510)2.58475257
30Obstructive lung disease (HP:0006536)2.58475257
31Aplasia/Hypoplasia of the sacrum (HP:0008517)2.56438087
32Type I transferrin isoform profile (HP:0003642)2.56016893
33Increased CSF lactate (HP:0002490)2.55560694
34Acute encephalopathy (HP:0006846)2.46810252
35Abnormality of dicarboxylic acid metabolism (HP:0010995)2.44656447
36Dicarboxylic aciduria (HP:0003215)2.44656447
37Prolonged neonatal jaundice (HP:0006579)2.43887324
38Purpura (HP:0000979)2.42171982
39Hepatosplenomegaly (HP:0001433)2.41036955
40Microretrognathia (HP:0000308)2.38439447
41Increased hepatocellular lipid droplets (HP:0006565)2.37765361
42Elevated erythrocyte sedimentation rate (HP:0003565)2.35652230
43Increased serum ferritin (HP:0003281)2.32784737
44Thrombocytosis (HP:0001894)2.32111509
45Abnormality of aromatic amino acid family metabolism (HP:0004338)2.30740618
46Lipid accumulation in hepatocytes (HP:0006561)2.29006673
47Exercise intolerance (HP:0003546)2.27806310
48Achilles tendon contracture (HP:0001771)2.24651826
49Lactic acidosis (HP:0003128)2.24468669
50Abnormal trabecular bone morphology (HP:0100671)2.23495292
51Progressive neurologic deterioration (HP:0002344)2.21259855
52Abnormality of macrophages (HP:0004311)2.19789611
53Vacuolated lymphocytes (HP:0001922)2.15711929
54Increased serum lactate (HP:0002151)2.11270183
55Recurrent abscess formation (HP:0002722)2.11223782
56Respiratory difficulties (HP:0002880)2.08444812
57Trismus (HP:0000211)2.08292820
58Hypokinesia (HP:0002375)2.06152822
59Abnormality of mucopolysaccharide metabolism (HP:0011020)2.05347995
60Abnormality of polysaccharide metabolism (HP:0011012)2.05347995
61Abnormality of glycosaminoglycan metabolism (HP:0004371)2.05347995
62Mediastinal lymphadenopathy (HP:0100721)2.05089164
63Cerebral edema (HP:0002181)2.05008016
64Loss of speech (HP:0002371)2.01966102
65Eczematoid dermatitis (HP:0000976)2.01872278
66Axonal loss (HP:0003447)1.99494145
67Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.98185118
68Abnormal protein N-linked glycosylation (HP:0012347)1.98185118
69Abnormal protein glycosylation (HP:0012346)1.98185118
70Abnormal glycosylation (HP:0012345)1.98185118
71Squamous cell carcinoma (HP:0002860)1.97958306
72Abnormality of the Achilles tendon (HP:0005109)1.96833545
73Reticulocytopenia (HP:0001896)1.96606327
74Recurrent bacterial skin infections (HP:0005406)1.95767352
75Gastrointestinal stroma tumor (HP:0100723)1.95379608
76Broad distal phalanx of finger (HP:0009836)1.94308290
77Myopathic facies (HP:0002058)1.93973716
78Progressive macrocephaly (HP:0004481)1.93128153
79Seborrheic dermatitis (HP:0001051)1.90544617
80Reduced subcutaneous adipose tissue (HP:0003758)1.89737713
81Multiple enchondromatosis (HP:0005701)1.89155944
82Cutaneous melanoma (HP:0012056)1.89032501
83Opisthotonus (HP:0002179)1.88839444
84Agammaglobulinemia (HP:0004432)1.86955890
85Systemic lupus erythematosus (HP:0002725)1.85514930
86Spastic paraparesis (HP:0002313)1.83016763
87Pancytopenia (HP:0001876)1.82660939
88Mucopolysacchariduria (HP:0008155)1.81979634
89Urinary glycosaminoglycan excretion (HP:0003541)1.81979634
90Joint stiffness (HP:0001387)1.81017336
91Reduced antithrombin III activity (HP:0001976)1.79723942
92Neoplasm of head and neck (HP:0012288)1.78617246
93Esophageal neoplasm (HP:0100751)1.78617246
94Recurrent viral infections (HP:0004429)1.78252767
95Cellulitis (HP:0100658)1.77230235
96Hypertriglyceridemia (HP:0002155)1.77101565
97Respiratory failure (HP:0002878)1.76750863
98Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.76645714
99Bulbar palsy (HP:0001283)1.76442710
100Exertional dyspnea (HP:0002875)1.76017605

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME25.27428653
2TESK24.26398742
3VRK23.98600404
4ERN13.07172040
5TESK12.96319310
6IRAK32.79214895
7SMG12.72420207
8ARAF2.52688256
9PIM22.45905509
10MAP3K112.38490534
11KDR2.37054647
12BCKDK2.19913104
13TRIB32.15421766
14BUB12.11909250
15MAP4K11.99115738
16TAOK21.95067754
17PRPF4B1.76556350
18LIMK11.58577527
19SIK11.57527197
20TBK11.50541633
21MAP2K31.48858756
22SCYL21.45815162
23STK161.43254390
24ABL21.40850514
25TLK11.32545229
26BRAF1.16767333
27ICK1.08176334
28MAPKAPK31.05254915
29EPHA21.04718867
30IKBKB1.04296985
31PRKD21.04027727
32MAP3K31.03478833
33AURKA1.03067840
34GRK60.99936004
35LRRK20.97979851
36PAK40.93375819
37NME10.91107431
38IRAK40.89114730
39TAOK10.88048690
40BLK0.84842381
41DAPK10.84429392
42TYK20.84099335
43ZAP700.81043864
44ILK0.80333089
45IKBKE0.78081513
46VRK10.77040457
47MAP3K80.76762622
48JAK30.74911895
49IRAK20.73281293
50MST1R0.72969438
51PRKD30.72144085
52MAP3K130.71241563
53MAPK110.70273748
54PRKCI0.67665093
55CDK40.66389383
56CDK70.66379883
57TNK20.66128954
58SIK30.66088596
59DAPK30.64429809
60PAK10.63613644
61EEF2K0.61893710
62PBK0.60766118
63RPS6KB20.59045608
64TXK0.58604850
65MAP2K20.56366553
66CDK80.55998459
67MAP3K10.55671288
68STK100.55295239
69PDPK10.54728255
70PDK20.53769923
71RPS6KA50.48826470
72TAF10.48448083
73CDK90.44018693
74MOS0.40619802
75MAP3K140.40421767
76CSK0.39582788
77MAPKAPK20.38747388
78LMTK20.38015506
79CSF1R0.36571810
80RPS6KC10.35615028
81RPS6KL10.35615028
82PIM10.35517900
83BTK0.35307159
84CHEK20.34951713
85HIPK20.33845355
86CDC70.33676007
87AURKB0.32923490
88PRKG20.31052928
89FES0.30198115
90BMX0.30068228
91LYN0.30056110
92MAP3K100.29373194
93SYK0.28919691
94CSNK1G30.28674930
95AKT20.28123628
96LCK0.27837692
97PTK60.26742510
98CCNB10.26481196
99RPS6KA20.26250276
100MAP2K60.25939013

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.83070191
2Sulfur relay system_Homo sapiens_hsa041223.55090093
3Proteasome_Homo sapiens_hsa030503.33044462
4DNA replication_Homo sapiens_hsa030302.91789276
5Base excision repair_Homo sapiens_hsa034102.66093983
6Other glycan degradation_Homo sapiens_hsa005112.57372083
7Oxidative phosphorylation_Homo sapiens_hsa001902.52002964
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12846269
9Pyrimidine metabolism_Homo sapiens_hsa002402.12494756
10RNA polymerase_Homo sapiens_hsa030202.08260384
11Parkinsons disease_Homo sapiens_hsa050122.07099295
12Primary immunodeficiency_Homo sapiens_hsa053402.04908901
13Glycosaminoglycan degradation_Homo sapiens_hsa005311.87246116
14Fructose and mannose metabolism_Homo sapiens_hsa000511.75136159
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74134525
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.63637546
17Huntingtons disease_Homo sapiens_hsa050161.51788909
18Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.49947536
19Folate biosynthesis_Homo sapiens_hsa007901.49795369
20Pentose phosphate pathway_Homo sapiens_hsa000301.46077206
21Mismatch repair_Homo sapiens_hsa034301.42394523
22Lysosome_Homo sapiens_hsa041421.41677472
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.40233792
24Biosynthesis of amino acids_Homo sapiens_hsa012301.39877190
25Spliceosome_Homo sapiens_hsa030401.38690071
26Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.36990847
27Glutathione metabolism_Homo sapiens_hsa004801.36605837
28Sulfur metabolism_Homo sapiens_hsa009201.36392073
29Galactose metabolism_Homo sapiens_hsa000521.35150441
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.34166776
31Antigen processing and presentation_Homo sapiens_hsa046121.31317546
32Alzheimers disease_Homo sapiens_hsa050101.27991168
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27367035
34Allograft rejection_Homo sapiens_hsa053301.24126827
35Autoimmune thyroid disease_Homo sapiens_hsa053201.16560941
36N-Glycan biosynthesis_Homo sapiens_hsa005101.14832097
37Cyanoamino acid metabolism_Homo sapiens_hsa004601.10043827
38Graft-versus-host disease_Homo sapiens_hsa053321.08526869
39Intestinal immune network for IgA production_Homo sapiens_hsa046721.03041900
40Nucleotide excision repair_Homo sapiens_hsa034201.00911571
41Epstein-Barr virus infection_Homo sapiens_hsa051690.98715732
42RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.97999281
43NF-kappa B signaling pathway_Homo sapiens_hsa040640.96316002
44Bladder cancer_Homo sapiens_hsa052190.95654086
45Fatty acid elongation_Homo sapiens_hsa000620.94921251
46Shigellosis_Homo sapiens_hsa051310.94800576
47Toll-like receptor signaling pathway_Homo sapiens_hsa046200.92903066
48Herpes simplex infection_Homo sapiens_hsa051680.92161488
49Carbon metabolism_Homo sapiens_hsa012000.92050553
50Vibrio cholerae infection_Homo sapiens_hsa051100.90930655
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89517721
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.89379928
53Homologous recombination_Homo sapiens_hsa034400.89157567
54Phenylalanine metabolism_Homo sapiens_hsa003600.87617458
55Rheumatoid arthritis_Homo sapiens_hsa053230.84361871
56Prion diseases_Homo sapiens_hsa050200.84022759
57Purine metabolism_Homo sapiens_hsa002300.83496814
58Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.81888804
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81395690
60Apoptosis_Homo sapiens_hsa042100.79927814
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.78529168
62Asthma_Homo sapiens_hsa053100.78406739
63Viral myocarditis_Homo sapiens_hsa054160.77800925
64Acute myeloid leukemia_Homo sapiens_hsa052210.75839810
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.73359749
66Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.73239551
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69995713
68Leishmaniasis_Homo sapiens_hsa051400.69845111
69Systemic lupus erythematosus_Homo sapiens_hsa053220.68077020
70Osteoclast differentiation_Homo sapiens_hsa043800.65482074
71HTLV-I infection_Homo sapiens_hsa051660.64894117
72Hematopoietic cell lineage_Homo sapiens_hsa046400.63949895
73Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63908509
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61170021
75Type I diabetes mellitus_Homo sapiens_hsa049400.59371018
76Metabolic pathways_Homo sapiens_hsa011000.59360306
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56582522
78Salmonella infection_Homo sapiens_hsa051320.56088644
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.55865454
80Tuberculosis_Homo sapiens_hsa051520.55508593
81Collecting duct acid secretion_Homo sapiens_hsa049660.54830349
82B cell receptor signaling pathway_Homo sapiens_hsa046620.54204661
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53112969
84One carbon pool by folate_Homo sapiens_hsa006700.51972585
85Influenza A_Homo sapiens_hsa051640.49134080
86Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48535796
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48116563
88Measles_Homo sapiens_hsa051620.47238418
89Staphylococcus aureus infection_Homo sapiens_hsa051500.45444375
90Pyruvate metabolism_Homo sapiens_hsa006200.43634668
91Viral carcinogenesis_Homo sapiens_hsa052030.41695433
92Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39244606
93Tyrosine metabolism_Homo sapiens_hsa003500.37553158
94Peroxisome_Homo sapiens_hsa041460.37486114
95Phagosome_Homo sapiens_hsa041450.36792496
96TNF signaling pathway_Homo sapiens_hsa046680.36504847
97Pertussis_Homo sapiens_hsa051330.35148550
98Fanconi anemia pathway_Homo sapiens_hsa034600.34120442
99RNA transport_Homo sapiens_hsa030130.31979442
100Legionellosis_Homo sapiens_hsa051340.31390846

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »