BTNL9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vascular endothelial growth factor signaling pathway (GO:0038084)6.59213711
2neutral lipid catabolic process (GO:0046461)6.16370224
3acylglycerol catabolic process (GO:0046464)6.16370224
4lymph vessel development (GO:0001945)6.03045638
5regulation of sequestering of triglyceride (GO:0010889)5.93404346
6fatty acid transmembrane transport (GO:1902001)5.75186920
7retina vasculature morphogenesis in camera-type eye (GO:0061299)5.54370500
8transcytosis (GO:0045056)4.86281560
9carnitine shuttle (GO:0006853)4.82813942
10response to dietary excess (GO:0002021)4.79761972
11glycerolipid catabolic process (GO:0046503)4.73026815
12endothelium development (GO:0003158)4.70408383
13lipid particle organization (GO:0034389)4.65479439
14cellular response to vascular endothelial growth factor stimulus (GO:0035924)4.64493316
15low-density lipoprotein particle clearance (GO:0034383)4.62260455
16cardiac myofibril assembly (GO:0055003)4.60281517
17positive regulation of glomerulus development (GO:0090193)4.30747687
18brown fat cell differentiation (GO:0050873)4.29201034
19sprouting angiogenesis (GO:0002040)4.28867614
20tricarboxylic acid cycle (GO:0006099)4.25480613
21venous blood vessel morphogenesis (GO:0048845)4.22944225
22sarcomere organization (GO:0045214)4.19001225
23myofibril assembly (GO:0030239)4.14097219
24regulation of relaxation of muscle (GO:1901077)4.07642521
25positive regulation of protein kinase C signaling (GO:0090037)3.99749714
26polyol transport (GO:0015791)3.97829411
27ethanol oxidation (GO:0006069)3.93378704
28negative regulation of appetite (GO:0032099)3.89896613
29negative regulation of response to food (GO:0032096)3.89896613
30regulation of actin filament-based movement (GO:1903115)3.88208261
31regulation of glycogen (starch) synthase activity (GO:2000465)3.87688291
32heart trabecula formation (GO:0060347)3.85285488
33regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.84723600
34ovulation from ovarian follicle (GO:0001542)3.83901085
35biotin metabolic process (GO:0006768)3.80641810
36fatty acid beta-oxidation (GO:0006635)3.80258754
37fatty acid homeostasis (GO:0055089)3.79373228
38carnitine transmembrane transport (GO:1902603)3.78850542
39glomerular filtration (GO:0003094)3.78427009
40surfactant homeostasis (GO:0043129)3.78245026
41positive regulation of glycolytic process (GO:0045821)3.78010060
42negative regulation of macrophage differentiation (GO:0045650)3.76078988
43regulation of sarcomere organization (GO:0060297)3.75831321
44negative regulation of nitric-oxide synthase activity (GO:0051001)3.73947809
45creatine metabolic process (GO:0006600)3.69123526
46vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.68674489
47negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)3.68038059
48regulation of lipoprotein metabolic process (GO:0050746)3.64813307
49regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.62905814
50lymphangiogenesis (GO:0001946)3.61344980
51cGMP-mediated signaling (GO:0019934)3.60150723
52valine metabolic process (GO:0006573)3.57454259
53phagocytosis, recognition (GO:0006910)3.54841495
54regulation of triglyceride catabolic process (GO:0010896)3.52394412
55coronary vasculature morphogenesis (GO:0060977)3.50616336
56positive regulation of vasculogenesis (GO:2001214)3.49607298
57regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.45703913
58regulation of fatty acid oxidation (GO:0046320)3.42947314
59detection of calcium ion (GO:0005513)3.42533465
60amino-acid betaine transport (GO:0015838)3.42469545
61carnitine transport (GO:0015879)3.42469545
62negative regulation of Rho protein signal transduction (GO:0035024)3.39967250
63adult feeding behavior (GO:0008343)3.39934728
64regulation of cholesterol storage (GO:0010885)3.39351644
65regulation of acyl-CoA biosynthetic process (GO:0050812)3.38672667
66negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.36118319
67diacylglycerol metabolic process (GO:0046339)3.35810072
68cardiac muscle hypertrophy (GO:0003300)3.35645748
69response to epinephrine (GO:0071871)3.35569153
70negative regulation of amino acid transport (GO:0051956)3.35496732
71protein heterotrimerization (GO:0070208)3.34869058
72blood vessel maturation (GO:0001955)3.34544684
73bundle of His cell to Purkinje myocyte communication (GO:0086069)3.34330562
74potassium ion export (GO:0071435)3.32619906
75regulation of gonadotropin secretion (GO:0032276)3.32151612
76regulation of cAMP-dependent protein kinase activity (GO:2000479)3.29358611
77NADH metabolic process (GO:0006734)3.27339841
78oxaloacetate metabolic process (GO:0006107)3.27039160
79negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.26584628
80ganglion development (GO:0061548)3.26183909
81neuron projection extension involved in neuron projection guidance (GO:1902284)3.25518345
82axon extension involved in axon guidance (GO:0048846)3.25518345
83endothelial cell morphogenesis (GO:0001886)3.24408579
84fatty acid oxidation (GO:0019395)3.23708212
85regulation of cardiac muscle cell contraction (GO:0086004)3.20445334
86lipid oxidation (GO:0034440)3.20200659
87regulation of vasculogenesis (GO:2001212)3.19187826
88triglyceride catabolic process (GO:0019433)3.18742333
89positive regulation of lipid storage (GO:0010884)3.17746971
90negative regulation of DNA biosynthetic process (GO:2000279)3.17521959
91triglyceride homeostasis (GO:0070328)3.15776934
92acylglycerol homeostasis (GO:0055090)3.15776934
93ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.15551310
94cardiac muscle contraction (GO:0060048)3.15276613
95positive regulation of fatty acid oxidation (GO:0046321)3.14764034
96lipid storage (GO:0019915)3.14623979
97renal filtration (GO:0097205)3.14054827
98positive regulation of vascular permeability (GO:0043117)3.12986489
99striated muscle hypertrophy (GO:0014897)3.12459124
100membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.10774845
101positive regulation of macrophage cytokine production (GO:0060907)3.08884128
102regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.08350224
103glycerol metabolic process (GO:0006071)3.06830016
104fatty acid catabolic process (GO:0009062)3.06795061
105tyrosine phosphorylation of STAT protein (GO:0007260)3.06761897
106chemical homeostasis within a tissue (GO:0048875)3.06060413
107cardiac muscle tissue morphogenesis (GO:0055008)3.05675684
108regulation of skeletal muscle contraction (GO:0014819)3.05449602
109phosphatidic acid biosynthetic process (GO:0006654)3.04231266
110phosphatidic acid metabolic process (GO:0046473)3.04231266
111cell migration involved in sprouting angiogenesis (GO:0002042)3.03120095
112negative regulation of gluconeogenesis (GO:0045721)3.01506595
113negative regulation of potassium ion transmembrane transport (GO:1901380)3.00543750
114carnitine metabolic process (GO:0009437)2.99240367
115regulation of endothelial cell differentiation (GO:0045601)2.98688229
116muscle filament sliding (GO:0030049)2.97694380
117actin-myosin filament sliding (GO:0033275)2.97694380
118plasma membrane repair (GO:0001778)2.96872808
119positive regulation of smooth muscle cell migration (GO:0014911)2.96701080
120plasma lipoprotein particle clearance (GO:0034381)2.96604750
121regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640)2.96546657
122cellular response to leptin stimulus (GO:0044320)2.96116386
1232-oxoglutarate metabolic process (GO:0006103)2.95330600
124positive regulation of lipoprotein lipase activity (GO:0051006)2.93920700
125positive regulation of triglyceride lipase activity (GO:0061365)2.93920700
126basement membrane organization (GO:0071711)2.93043860
127response to phenylpropanoid (GO:0080184)2.92416149
128branched-chain amino acid catabolic process (GO:0009083)2.90772893
129white fat cell differentiation (GO:0050872)2.90475084
130branched-chain amino acid metabolic process (GO:0009081)2.88966069
131negative regulation of granulocyte differentiation (GO:0030853)2.88387140
132ethanol metabolic process (GO:0006067)2.88109239
133regulation of macrophage derived foam cell differentiation (GO:0010743)2.88088461
134regulation of cofactor metabolic process (GO:0051193)2.88058867
135regulation of coenzyme metabolic process (GO:0051196)2.88058867
136tricarboxylic acid metabolic process (GO:0072350)2.86817448
137negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.85414775
138muscle hypertrophy (GO:0014896)2.85270905
139regulation of the force of heart contraction (GO:0002026)2.85196531
140regulation of lipid storage (GO:0010883)2.84840224
141regulation of protein kinase A signaling (GO:0010738)2.84329992
142substrate-dependent cell migration (GO:0006929)2.84159699
143positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.83291549
144phenol-containing compound catabolic process (GO:0019336)2.82882301
145patterning of blood vessels (GO:0001569)2.81860440
146succinate metabolic process (GO:0006105)2.81647745
147actomyosin structure organization (GO:0031032)2.78652474
148cardiac muscle cell development (GO:0055013)2.77862958
149adrenergic receptor signaling pathway (GO:0071875)2.77413898
150cardiac cell development (GO:0055006)2.76880881
151negative regulation of endothelial cell migration (GO:0010596)2.76001805
152cellular response to epinephrine stimulus (GO:0071872)2.75867741
153positive regulation of metanephros development (GO:0072216)2.75537195
154negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.75415028
155ventricular cardiac muscle cell action potential (GO:0086005)2.75403905
156primary alcohol metabolic process (GO:0034308)2.73831393
157regulation of glomerulus development (GO:0090192)2.71017141
158cAMP catabolic process (GO:0006198)2.71009343
159regulation of triglyceride biosynthetic process (GO:0010866)2.70439130
160response to leptin (GO:0044321)2.68811428
161response to vitamin E (GO:0033197)2.68634474
162negative regulation of protein autophosphorylation (GO:0031953)2.66555430
163behavioral response to nicotine (GO:0035095)2.65636560
164endocrine hormone secretion (GO:0060986)2.63610235
165somite development (GO:0061053)2.63511696
166negative regulation of metanephros development (GO:0072217)2.63290588
167positive regulation of fatty acid metabolic process (GO:0045923)2.62664220
168positive regulation of triglyceride metabolic process (GO:0090208)2.59267843

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.91771677
2EZH2_22144423_ChIP-Seq_EOC_Human4.95924427
3GATA1_22025678_ChIP-Seq_K562_Human4.85801007
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.01114617
5TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.42905590
6GATA2_21666600_ChIP-Seq_HMVEC_Human3.22237140
7VDR_22108803_ChIP-Seq_LS180_Human3.14616143
8EP300_21415370_ChIP-Seq_HL-1_Mouse3.02148823
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.76918692
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.62982860
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.51924651
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.29925884
13TBX20_22080862_ChIP-Seq_HEART_Mouse2.28865675
14TBX20_22328084_ChIP-Seq_HEART_Mouse2.28865675
15CLOCK_20551151_ChIP-Seq_293T_Human2.06162535
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.05975760
17CDX2_19796622_ChIP-Seq_MESCs_Mouse2.00643836
18ZNF274_21170338_ChIP-Seq_K562_Hela1.98058285
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.96611119
20ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.87756444
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.81014593
22NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.80511819
23IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.80405098
24SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.76373441
25ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.76210191
26LXR_22158963_ChIP-Seq_LIVER_Mouse1.71218849
27IGF1R_20145208_ChIP-Seq_DFB_Human1.70376463
28FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.70278119
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.70037944
30DROSHA_22980978_ChIP-Seq_HELA_Human1.69406187
31CJUN_26792858_Chip-Seq_BT549_Human1.65659881
32PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.62396575
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.61869430
34PPAR_26484153_Chip-Seq_NCI-H1993_Human1.60958351
35IRF8_22096565_ChIP-ChIP_GC-B_Human1.60550983
36ESR1_20079471_ChIP-ChIP_T-47D_Human1.60316827
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.59577156
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.58551213
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.54465636
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.54160698
41GBX2_23144817_ChIP-Seq_PC3_Human1.46544099
42JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45834942
43SCL_19346495_ChIP-Seq_HPC-7_Human1.45520858
44CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.45509790
45RXR_22158963_ChIP-Seq_LIVER_Mouse1.44997538
46BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.44725649
47RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43546664
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.42539996
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42468415
50TCF4_18268006_ChIP-ChIP_LS174T_Human1.42134738
51EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.39762556
52MTF2_20144788_ChIP-Seq_MESCs_Mouse1.39128994
53LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.38051880
54EZH2_18974828_ChIP-Seq_MESCs_Mouse1.37544185
55RNF2_18974828_ChIP-Seq_MESCs_Mouse1.37544185
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36816133
57SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.36568892
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33441546
59PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.33312469
60SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.32773917
61SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31336467
62* GATA3_21878914_ChIP-Seq_MCF-7_Human1.30525594
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29907703
64VDR_24787735_ChIP-Seq_THP-1_Human1.28123968
65RUNX_20019798_ChIP-Seq_JUKART_Human1.27701995
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27545671
67ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25551251
68MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.22906583
69ER_23166858_ChIP-Seq_MCF-7_Human1.21579675
70PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21123598
71ERA_21632823_ChIP-Seq_H3396_Human1.20047266
72PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.19601893
73TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.19429990
74PPARA_22158963_ChIP-Seq_LIVER_Mouse1.19381618
75WT1_19549856_ChIP-ChIP_CCG9911_Human1.19349715
76MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.19204516
77Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.16522179
78STAT3_23295773_ChIP-Seq_U87_Human1.16040365
79CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15817832
80NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.13900580
81JARID2_20064375_ChIP-Seq_MESCs_Mouse1.12604701
82PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11890017
83BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11218680
84GATA4_21415370_ChIP-Seq_HL-1_Mouse1.10858395
85PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10644482
86NRF2_20460467_ChIP-Seq_MEFs_Mouse1.09254179
87NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.09254179
88PIAS1_25552417_ChIP-Seq_VCAP_Human1.08155211
89SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.07481992
90SUZ12_27294783_Chip-Seq_ESCs_Mouse1.06939844
91CTCF_27219007_Chip-Seq_Bcells_Human1.06579834
92CTBP1_25329375_ChIP-Seq_LNCAP_Human1.06067241
93* TCF4_23295773_ChIP-Seq_U87_Human1.05556403
94RNF2_27304074_Chip-Seq_ESCs_Mouse1.04725257
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.03842663
96AR_25329375_ChIP-Seq_VCAP_Human1.03730782
97BCAT_22108803_ChIP-Seq_LS180_Human1.03141661
98GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.02170100
99REST_21632747_ChIP-Seq_MESCs_Mouse1.01873074
100AHR_22903824_ChIP-Seq_MCF-7_Human1.01640156
101FOXH1_21741376_ChIP-Seq_ESCs_Human1.00895778
102* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99748223
103GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99549413
104TP53_16413492_ChIP-PET_HCT116_Human0.99486379
105SALL4_18804426_ChIP-ChIP_XEN_Mouse0.99418435
106SOX9_24532713_ChIP-Seq_HFSC_Mouse0.99149577
107RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98434962
108RNF2_27304074_Chip-Seq_NSC_Mouse0.98101174
109SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.97985053
110THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96715607
111FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96555156
112FOXA1_25329375_ChIP-Seq_VCAP_Human0.96555156
113TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.95997806
114SALL1_21062744_ChIP-ChIP_HESCs_Human0.95675410
115ETV2_25802403_ChIP-Seq_MESCs_Mouse0.95479923
116CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94848162
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.94720557
118SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.94131256
119AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.93909410
120SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.93781228
121GATA1_19941826_ChIP-Seq_K562_Human0.93700911
122TCF4_22108803_ChIP-Seq_LS180_Human0.93677740
123EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.93500056
124RUNX2_22187159_ChIP-Seq_PCA_Human0.91801232
125FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.91692628
126WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91132977
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90702934
128EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.90698620
129TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90215667
130POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90215667
131CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.89870231
132CBP_21632823_ChIP-Seq_H3396_Human0.89260299
133* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88326828
134TBL1_22424771_ChIP-Seq_293T_Human0.87954526
135TP53_18474530_ChIP-ChIP_U2OS_Human0.87707731
136P53_21459846_ChIP-Seq_SAOS-2_Human0.87624841
137TOP2B_26459242_ChIP-Seq_MCF-7_Human0.87549978
138* TAF2_19829295_ChIP-Seq_ESCs_Human0.86439084
139EZH2_27294783_Chip-Seq_NPCs_Mouse0.86327041
140NR3C1_21868756_ChIP-Seq_MCF10A_Human0.86323382
141SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.85139670
142IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84950076
143CBP_20019798_ChIP-Seq_JUKART_Human0.84950076
144MYC_19829295_ChIP-Seq_ESCs_Human0.84762932
145FLI1_27457419_Chip-Seq_LIVER_Mouse0.84451397
146RXR_22108803_ChIP-Seq_LS180_Human0.84290563
147SMAD4_21741376_ChIP-Seq_HESCs_Human0.84180936
148OCT4_20526341_ChIP-Seq_ESCs_Human0.83985503
149CDX2_22108803_ChIP-Seq_LS180_Human0.83757963
150CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.83740269
151GATA2_19941826_ChIP-Seq_K562_Human0.83362709
152FOXO3_23340844_ChIP-Seq_DLD1_Human0.82822825
153PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82263781
154IRF8_27001747_Chip-Seq_BMDM_Mouse0.81682296
155TAF15_26573619_Chip-Seq_HEK293_Human0.79811814
156SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79560224
157TP63_23658742_ChIP-Seq_EP156T_Human0.79450879
158NR3C1_23031785_ChIP-Seq_PC12_Mouse0.79447533
159FOXA2_19822575_ChIP-Seq_HepG2_Human0.79125532
160SMAD4_21799915_ChIP-Seq_A2780_Human0.78771715
161ZFP57_27257070_Chip-Seq_ESCs_Mouse0.78597137
162MYB_21317192_ChIP-Seq_ERMYB_Mouse0.78421644
163* SOX2_20726797_ChIP-Seq_SW620_Human0.78017883
164EGR1_23403033_ChIP-Seq_LIVER_Mouse0.77974264
165BRD4_25478319_ChIP-Seq_HGPS_Human0.77142250
166P300_19829295_ChIP-Seq_ESCs_Human0.76970984

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005670_abnormal_white_adipose4.90133004
2MP0010368_abnormal_lymphatic_system4.42574487
3MP0004215_abnormal_myocardial_fiber4.00535379
4MP0002837_dystrophic_cardiac_calcinosis3.98079127
5MP0004084_abnormal_cardiac_muscle3.95733872
6MP0001879_abnormal_lymphatic_vessel3.87716928
7MP0004130_abnormal_muscle_cell3.68187156
8MP0003828_pulmonary_edema3.50685833
9MP0003724_increased_susceptibility_to3.36517751
10MP0003646_muscle_fatigue2.96059299
11MP0004272_abnormal_basement_membrane2.95367103
12MP0000751_myopathy2.78582784
13MP0004036_abnormal_muscle_relaxation2.69274492
14MP0004145_abnormal_muscle_electrophysio2.65034654
15MP0005666_abnormal_adipose_tissue2.63344124
16MP0005330_cardiomyopathy2.55630817
17MP0008775_abnormal_heart_ventricle2.36227346
18MP0003959_abnormal_lean_body2.32872855
19MP0006138_congestive_heart_failure2.32685501
20MP0002972_abnormal_cardiac_muscle2.29194711
21MP0004147_increased_porphyrin_level2.23259929
22MP0003011_delayed_dark_adaptation2.21495441
23MP0005385_cardiovascular_system_phenoty2.17663355
24MP0001544_abnormal_cardiovascular_syste2.17663355
25MP0000749_muscle_degeneration2.08229555
26MP0000343_altered_response_to2.05114042
27MP0004484_altered_response_of1.99438525
28MP0005620_abnormal_muscle_contractility1.94407723
29MP0010630_abnormal_cardiac_muscle1.91214968
30MP0004185_abnormal_adipocyte_glucose1.81049838
31MP0005375_adipose_tissue_phenotype1.80714810
32MP0002332_abnormal_exercise_endurance1.79606137
33MP0004087_abnormal_muscle_fiber1.78972460
34MP0003950_abnormal_plasma_membrane1.76597297
35MP0000013_abnormal_adipose_tissue1.76045666
36MP0000750_abnormal_muscle_regeneration1.75033416
37MP0001501_abnormal_sleep_pattern1.71829658
38MP0006276_abnormal_autonomic_nervous1.71141526
39MP0005448_abnormal_energy_balance1.57521333
40MP0003279_aneurysm1.56918724
41MP0005167_abnormal_blood-brain_barrier1.55553216
42MP0005165_increased_susceptibility_to1.51299092
43MP0004085_abnormal_heartbeat1.50096525
44MP0002108_abnormal_muscle_morphology1.49130708
45MP0005503_abnormal_tendon_morphology1.43194502
46MP0002127_abnormal_cardiovascular_syste1.35766604
47MP0009780_abnormal_chondrocyte_physiolo1.33518928
48MP0002971_abnormal_brown_adipose1.33369334
49MP0003137_abnormal_impulse_conducting1.29570642
50MP0002909_abnormal_adrenal_gland1.28449972
51MP0002106_abnormal_muscle_physiology1.28231940
52MP0006054_spinal_hemorrhage1.28154360
53MP0000003_abnormal_adipose_tissue1.26971315
54MP0004510_myositis1.25003990
55MP0008995_early_reproductive_senescence1.24197868
56MP0009115_abnormal_fat_cell1.23894608
57MP0009697_abnormal_copulation1.23774894
58MP0005452_abnormal_adipose_tissue1.20957530
59MP0003566_abnormal_cell_adhesion1.20829792
60MP0001853_heart_inflammation1.18358828
61MP0000767_abnormal_smooth_muscle1.14488604
62MP0006036_abnormal_mitochondrial_physio1.13121609
63MP0005379_endocrine/exocrine_gland_phen1.12586664
64MP0005266_abnormal_metabolism1.11171857
65MP0005551_abnormal_eye_electrophysiolog1.09728573
66MP0000230_abnormal_systemic_arterial1.02238835
67MP0002128_abnormal_blood_circulation1.00917318
68MP0000266_abnormal_heart_morphology0.98676168
69MP0005369_muscle_phenotype0.98252894
70MP0002295_abnormal_pulmonary_circulatio0.97599275
71MP0003045_fibrosis0.96782585
72MP0005334_abnormal_fat_pad0.95419802
73MP0010329_abnormal_lipoprotein_level0.95111661
74MP0001764_abnormal_homeostasis0.94282552
75MP0005595_abnormal_vascular_smooth0.94112111
76MP0000759_abnormal_skeletal_muscle0.91924631
77MP0005171_absent_coat_pigmentation0.89583077
78MP0001881_abnormal_mammary_gland0.87709922
79MP0005647_abnormal_sex_gland0.87528482
80MP0004782_abnormal_surfactant_physiolog0.87468938
81MP0003868_abnormal_feces_composition0.87084443
82MP0005535_abnormal_body_temperature0.86736704
83MP0003191_abnormal_cellular_cholesterol0.86546600
84MP0000249_abnormal_blood_vessel0.85126874
85MP0003948_abnormal_gas_homeostasis0.83242137
86MP0008438_abnormal_cutaneous_collagen0.83170566
87MP0002876_abnormal_thyroid_physiology0.82981125
88MP0001502_abnormal_circadian_rhythm0.82452026
89MP0003221_abnormal_cardiomyocyte_apopto0.82217780
90MP0002118_abnormal_lipid_homeostasis0.81172531
91MP0002269_muscular_atrophy0.79578199
92MP0003690_abnormal_glial_cell0.79266334
93MP0003186_abnormal_redox_activity0.78609089
94MP0003953_abnormal_hormone_level0.78352962
95MP0002166_altered_tumor_susceptibility0.78314117
96MP0009764_decreased_sensitivity_to0.77251394
97MP0002933_joint_inflammation0.76815007
98MP0000747_muscle_weakness0.75659700
99MP0001614_abnormal_blood_vessel0.75549703
100MP0002396_abnormal_hematopoietic_system0.75398023
101MP0002925_abnormal_cardiovascular_devel0.75028354
102MP0002733_abnormal_thermal_nociception0.74483814
103MP0001661_extended_life_span0.71845774
104MP0003879_abnormal_hair_cell0.71699015
105MP0005409_darkened_coat_color0.70489782
106MP0005319_abnormal_enzyme/_coenzyme0.70403745
107MP0004924_abnormal_behavior0.70215316
108MP0005386_behavior/neurological_phenoty0.70215316
109MP0005365_abnormal_bile_salt0.69338584
110MP0003300_gastrointestinal_ulcer0.68960817
111MP0001440_abnormal_grooming_behavior0.68144678
112MP0005397_hematopoietic_system_phenotyp0.66930822
113MP0001545_abnormal_hematopoietic_system0.66930822
114MP0002078_abnormal_glucose_homeostasis0.66309454
115MP0009278_abnormal_bone_marrow0.66131426
116MP0009785_altered_susceptibility_to0.65987586
117MP0005275_abnormal_skin_tensile0.64982821
118MP0005332_abnormal_amino_acid0.64542916
119MP0008004_abnormal_stomach_pH0.64449541
120MP0009643_abnormal_urine_homeostasis0.64268837
121MP0005164_abnormal_response_to0.63994218
122MP0005645_abnormal_hypothalamus_physiol0.63180557
123MP0004043_abnormal_pH_regulation0.63012640
124MP0005388_respiratory_system_phenotype0.61413641
125MP0002133_abnormal_respiratory_system0.61413641
126MP0003136_yellow_coat_color0.60930175
127MP0002970_abnormal_white_adipose0.60688121
128MP0001188_hyperpigmentation0.60641186
129MP0003195_calcinosis0.60209760
130MP0000372_irregular_coat_pigmentation0.59782241
131MP0005646_abnormal_pituitary_gland0.59590547
132MP0002272_abnormal_nervous_system0.59476176
133MP0004885_abnormal_endolymph0.58463200
134MP0001968_abnormal_touch/_nociception0.58386908
135MP0001958_emphysema0.57761934
136MP0009763_increased_sensitivity_to0.57368575
137MP0002006_tumorigenesis0.57192376
138MP0003567_abnormal_fetal_cardiomyocyte0.55157024
139MP0000609_abnormal_liver_physiology0.54384632
140MP0003252_abnormal_bile_duct0.50057197
141MP0002638_abnormal_pupillary_reflex0.49076471

Predicted human phenotypes

RankGene SetZ-score
1Ventricular tachycardia (HP:0004756)5.89971088
2Sudden death (HP:0001699)5.54643443
3Atrial fibrillation (HP:0005110)5.38541800
4Muscle fiber splitting (HP:0003555)4.92860557
5Primary atrial arrhythmia (HP:0001692)4.89808012
6Supraventricular arrhythmia (HP:0005115)4.85979948
7Lipoatrophy (HP:0100578)4.85556960
8Supraventricular tachycardia (HP:0004755)4.69174602
9Hypoglycemic coma (HP:0001325)4.19388405
10Increased connective tissue (HP:0009025)4.13916379
11Myoglobinuria (HP:0002913)3.97466663
12Right ventricular cardiomyopathy (HP:0011663)3.93524020
13Hyporeflexia of lower limbs (HP:0002600)3.80007568
14Dilated cardiomyopathy (HP:0001644)3.78312861
15Palpitations (HP:0001962)3.73668042
16Prolonged QT interval (HP:0001657)3.67672264
17Syncope (HP:0001279)3.57518486
18Calf muscle hypertrophy (HP:0008981)3.53695680
19Subaortic stenosis (HP:0001682)3.46099387
20Abnormality of the left ventricular outflow tract (HP:0011103)3.46099387
21Insulin-resistant diabetes mellitus (HP:0000831)3.43359665
22Exercise-induced myalgia (HP:0003738)3.38160169
23Difficulty running (HP:0009046)3.37357230
24Abnormality of fatty-acid metabolism (HP:0004359)3.27826145
25Rhabdomyolysis (HP:0003201)3.21150214
26Hyperglycinuria (HP:0003108)3.06709778
27Dicarboxylic aciduria (HP:0003215)3.06193239
28Abnormality of dicarboxylic acid metabolism (HP:0010995)3.06193239
29Frequent falls (HP:0002359)3.05888604
30Polycythemia (HP:0001901)3.00867927
31Decreased circulating renin level (HP:0003351)3.00642623
32Type 1 muscle fiber predominance (HP:0003803)3.00510902
33Ketoacidosis (HP:0001993)2.97566881
34Muscle hypertrophy of the lower extremities (HP:0008968)2.94767348
35Muscle fiber inclusion bodies (HP:0100299)2.92965787
36Abnormality of the calf musculature (HP:0001430)2.91513221
37Reduced subcutaneous adipose tissue (HP:0003758)2.86666540
38Oligomenorrhea (HP:0000876)2.86497345
39Abnormality of skeletal muscle fiber size (HP:0012084)2.85850498
40Atrioventricular block (HP:0001678)2.85394560
41Hyperlipoproteinemia (HP:0010980)2.84784325
42Renal cortical cysts (HP:0000803)2.82052463
43Neck muscle weakness (HP:0000467)2.80378619
44Broad metatarsal (HP:0001783)2.79853361
45Tetraparesis (HP:0002273)2.78450914
46Heart block (HP:0012722)2.77476469
47Acanthosis nigricans (HP:0000956)2.77456190
48Abnormal eating behavior (HP:0100738)2.76838181
49Prominent supraorbital ridges (HP:0000336)2.76519356
50Hypertriglyceridemia (HP:0002155)2.72523325
51Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.70999347
52Generalized aminoaciduria (HP:0002909)2.70901080
53Rimmed vacuoles (HP:0003805)2.67842696
54EMG: myopathic abnormalities (HP:0003458)2.67766708
55Exercise-induced muscle cramps (HP:0003710)2.66497503
56Bundle branch block (HP:0011710)2.63118591
57Nausea (HP:0002018)2.62549677
58Asymmetric septal hypertrophy (HP:0001670)2.61427317
59Hypoplastic ischia (HP:0003175)2.60344950
60Nemaline bodies (HP:0003798)2.58815872
61Abnormal EKG (HP:0003115)2.58494542
62Congenital stationary night blindness (HP:0007642)2.56702253
63Ventricular arrhythmia (HP:0004308)2.56475479
64Hepatic necrosis (HP:0002605)2.55920955
65Abnormal atrioventricular conduction (HP:0005150)2.55585121
66Bone cyst (HP:0012062)2.55199920
67Pulmonary artery stenosis (HP:0004415)2.55125051
68Increased muscle lipid content (HP:0009058)2.53776358
69Esophageal varix (HP:0002040)2.52722175
70Abnormality of the ischium (HP:0003174)2.51696977
71Congenital, generalized hypertrichosis (HP:0004540)2.51385882
72Hemorrhage of the eye (HP:0011885)2.50999776
73Facial diplegia (HP:0001349)2.50879736
74Adactyly (HP:0009776)2.49798923
75Myotonia (HP:0002486)2.44764533
76Large hands (HP:0001176)2.43767500
77Pigmentary retinal degeneration (HP:0001146)2.41540629
78Tachypnea (HP:0002789)2.39448711
79Polyphagia (HP:0002591)2.38473840
80Delayed CNS myelination (HP:0002188)2.37786772
81Abnormality of the renal cortex (HP:0011035)2.37443592
82Areflexia of lower limbs (HP:0002522)2.36882145
83Epidermoid cyst (HP:0200040)2.36324315
84Aplasia cutis congenita (HP:0001057)2.34558681
85Hyperinsulinemic hypoglycemia (HP:0000825)2.33350985
86Cerebral palsy (HP:0100021)2.33321472
87Abnormal hemoglobin (HP:0011902)2.33003213
88Hypoglycemic seizures (HP:0002173)2.32504594
89Toxemia of pregnancy (HP:0100603)2.31458077
90Hyperglycemia (HP:0003074)2.30099881
91Large for gestational age (HP:0001520)2.30078907
92Distal lower limb muscle weakness (HP:0009053)2.30008763
93Lymphangioma (HP:0100764)2.29049983
94Duplicated collecting system (HP:0000081)2.28391275
95Broad-based gait (HP:0002136)2.27575767
96Growth hormone excess (HP:0000845)2.24764004
97Neonatal death (HP:0003811)2.24194894
98Ketosis (HP:0001946)2.20246984
99Insulin resistance (HP:0000855)2.18420568
100Abnormality of the renal collecting system (HP:0004742)2.17465792
101Hyperventilation (HP:0002883)2.17231708
102Hypoalphalipoproteinemia (HP:0003233)2.17042666
103Pancreatic cysts (HP:0001737)2.16763648
104Abnormality of serine family amino acid metabolism (HP:0010894)2.16416536
105Abnormality of glycine metabolism (HP:0010895)2.16416536
106Testicular atrophy (HP:0000029)2.14111613
107Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.13308968
108Impulsivity (HP:0100710)2.12933957
109Pancreatic fibrosis (HP:0100732)2.12252829
110Nephronophthisis (HP:0000090)2.09493104
111Abnormality of alanine metabolism (HP:0010916)2.07452822
112Hyperalaninemia (HP:0003348)2.07452822
113Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.07452822
114Abnormality of midbrain morphology (HP:0002418)2.06423817
115Molar tooth sign on MRI (HP:0002419)2.06423817
116Polydipsia (HP:0001959)2.05649286
117Abnormal drinking behavior (HP:0030082)2.05649286
118Inability to walk (HP:0002540)2.03952235
119Nonimmune hydrops fetalis (HP:0001790)2.03556646
120Porencephaly (HP:0002132)2.03350621
121Portal hypertension (HP:0001409)2.03223175
122Left ventricular hypertrophy (HP:0001712)2.01194373
123Gowers sign (HP:0003391)2.01139604
124Increased serum pyruvate (HP:0003542)1.99749775
125Hyperammonemia (HP:0001987)1.99341745
126Accelerated skeletal maturation (HP:0005616)1.96673653
127Increased variability in muscle fiber diameter (HP:0003557)1.95356027
128Spontaneous hematomas (HP:0007420)1.95108094
129Cerebral aneurysm (HP:0004944)1.94146976
130Palmoplantar keratoderma (HP:0000982)1.94087531
131Ileus (HP:0002595)1.93100006
132Ventricular fibrillation (HP:0001663)1.92945349
133Skin nodule (HP:0200036)1.92691806
134Complement deficiency (HP:0004431)1.90863034
135EMG: neuropathic changes (HP:0003445)1.90704243
136Abnormality of the renal medulla (HP:0100957)1.90330175
137Type II lissencephaly (HP:0007260)1.89427516
138Prenatal maternal abnormality (HP:0002686)1.88932637
139Hyperkalemia (HP:0002153)1.88429369
140Abnormality of the hepatic vasculature (HP:0006707)1.87565007
141Skull defect (HP:0001362)1.86233334
142Proximal tubulopathy (HP:0000114)1.85849470
143Mesangial abnormality (HP:0001966)1.85567317
144Infantile muscular hypotonia (HP:0008947)1.83958449
145Ulnar claw (HP:0001178)1.82018263
146Difficulty walking (HP:0002355)1.80892482
147True hermaphroditism (HP:0010459)1.77671627
148Abnormality of glycolysis (HP:0004366)1.77167970
149Cystic liver disease (HP:0006706)1.76505599
150Long foot (HP:0001833)1.75950899

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE17.74266982
2KDR5.91141142
3INSRR2.98181133
4MYLK2.67197828
5TGFBR22.49120381
6ZAK2.46968689
7TTN2.40990490
8PDK22.16631056
9PDK42.06946517
10PDK32.06946517
11BCKDK2.06020051
12CAMK1D1.97885746
13MARK11.97738152
14OBSCN1.95597981
15RIPK11.92096822
16IRAK31.85832165
17ADRBK21.81525247
18DMPK1.75278281
19LMTK21.74446492
20WNK41.71842694
21PIK3CA1.66967673
22FGFR31.62677496
23MAPK131.60300866
24NTRK31.59920714
25DAPK21.49381264
26CAMKK21.40026101
27TGFBR11.35855924
28PHKG21.35551874
29PHKG11.35551874
30ADRBK11.33991483
31PRKAA21.33534272
32GRK51.32623433
33MAP4K21.29250673
34PKN11.28823921
35SIK11.24426543
36CAMK1G1.22284741
37MAPK121.16703245
38TAOK31.15805715
39TEC1.12884858
40MAP2K11.10331776
41PINK11.10243381
42MAPK151.09562909
43NME11.09267118
44NEK91.06605631
45WNK31.06246052
46PAK31.06000318
47EEF2K1.04539049
48TRIB31.03503002
49IRAK41.02209304
50MAP3K41.01318175
51PRKG11.01062050
52PTK2B1.01039076
53JAK10.99501300
54TNIK0.99243883
55PRKD10.92828462
56JAK30.92421649
57TRPM70.91450216
58MAP2K30.90012422
59TLK10.87897889
60STK240.87806763
61MAP3K140.85551725
62DDR20.85549146
63MAP2K60.84194291
64PRKACA0.82151882
65EPHB20.80386849
66FRK0.79089036
67RIPK40.77928149
68GRK70.77454365
69MUSK0.77094550
70MAPK70.76539517
71CAMK40.75155230
72PRKAA10.72424774
73MAPKAPK50.69418151
74CDK90.66579382
75MAP2K40.65189704
76TNK20.64640205
77PKN20.63686699
78FLT30.62781194
79CAMK2A0.61763678
80RPS6KA30.61133835
81PRKCH0.61100557
82GRK10.59861974
83CSK0.59443371
84PRKG20.58765631
85FGFR40.58495191
86STK110.57679060
87KIT0.57511385
88SGK20.57106620
89FER0.56270932
90MAP3K30.56228450
91CAMK10.55806846
92PIK3CG0.55721231
93TYRO30.53588191
94EIF2AK20.53395719
95IGF1R0.52876666
96MAPK30.51357847
97EPHB10.51066170
98PRKCE0.50539218
99PDPK10.50124902
100AKT30.49664146
101MARK30.48311588
102SGK30.47609727
103MAP3K70.47527806
104BMPR1B0.47354908
105ABL20.46907280
106MAPKAPK30.45462611
107STK390.45335967
108AKT20.43805122
109MARK20.43077353
110JAK20.42963915
111MKNK20.42124621
112EPHA30.41974480
113BCR0.40059734
114IRAK10.39677388
115LATS10.39594186
116ERN10.37763983
117STK40.37160613
118TBK10.35167501
119PDK10.34695619
120PRKCA0.34552928
121PRKACG0.34193030
122PDGFRA0.33917100
123CASK0.33668761
124HIPK20.33209083
125OXSR10.32901559
126BRSK20.32882728
127SIK30.31801821
128MAPK10.31662065
129SGK10.31521468
130PRKCG0.31455518
131ABL10.30943689
132PRKACB0.30237719
133CAMK2D0.29622538
134MAPK40.29058578
135TXK0.28550309
136CDC42BPA0.28249110
137NLK0.27557186
138MAP3K50.27527158
139FGFR20.27108563
140ILK0.26918020
141STK38L0.26898634
142TYK20.26865869
143GSK3A0.26587935
144MAP3K60.26394932
145ROCK10.25979099
146NUAK10.25571183
147CDK80.25477159
148PRKCQ0.25202170

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.95996787
2Propanoate metabolism_Homo sapiens_hsa006404.30645349
3Fatty acid degradation_Homo sapiens_hsa000713.64538465
4Fatty acid metabolism_Homo sapiens_hsa012123.18973330
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.12597494
6PPAR signaling pathway_Homo sapiens_hsa033203.11904700
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.07826944
8Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.51470881
9Fatty acid biosynthesis_Homo sapiens_hsa000612.50134925
10Dilated cardiomyopathy_Homo sapiens_hsa054142.40004167
11Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.30870231
12Histidine metabolism_Homo sapiens_hsa003401.94095885
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.91377659
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.91027912
15Linoleic acid metabolism_Homo sapiens_hsa005911.87629340
16Carbon metabolism_Homo sapiens_hsa012001.69547930
17beta-Alanine metabolism_Homo sapiens_hsa004101.68819956
18Fatty acid elongation_Homo sapiens_hsa000621.65767867
19Caffeine metabolism_Homo sapiens_hsa002321.64598977
20Pyruvate metabolism_Homo sapiens_hsa006201.62839193
21ECM-receptor interaction_Homo sapiens_hsa045121.57155484
22Adipocytokine signaling pathway_Homo sapiens_hsa049201.56147289
23Nitrogen metabolism_Homo sapiens_hsa009101.55682387
24Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.55283744
25Cardiac muscle contraction_Homo sapiens_hsa042601.48077071
26Insulin resistance_Homo sapiens_hsa049311.41746679
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.39516799
28Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.39484689
29Tryptophan metabolism_Homo sapiens_hsa003801.37361085
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36323578
31Peroxisome_Homo sapiens_hsa041461.31159317
32Morphine addiction_Homo sapiens_hsa050321.30141751
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.27001441
34Viral myocarditis_Homo sapiens_hsa054161.21409776
35Lysine degradation_Homo sapiens_hsa003101.17329556
36Butanoate metabolism_Homo sapiens_hsa006501.17016815
37Focal adhesion_Homo sapiens_hsa045101.16920908
38Phototransduction_Homo sapiens_hsa047441.14506482
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.14445034
40Ether lipid metabolism_Homo sapiens_hsa005651.12249433
41Nicotine addiction_Homo sapiens_hsa050331.10336578
42Retinol metabolism_Homo sapiens_hsa008301.10209306
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07598726
44Malaria_Homo sapiens_hsa051441.06382277
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03511981
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.01597755
47Glycerolipid metabolism_Homo sapiens_hsa005611.01004681
48Glycerophospholipid metabolism_Homo sapiens_hsa005641.00505123
49Chemical carcinogenesis_Homo sapiens_hsa052040.99864032
50Starch and sucrose metabolism_Homo sapiens_hsa005000.99841417
51Parkinsons disease_Homo sapiens_hsa050120.95216880
52AMPK signaling pathway_Homo sapiens_hsa041520.94900306
53Olfactory transduction_Homo sapiens_hsa047400.93943228
54Adherens junction_Homo sapiens_hsa045200.93691974
55Toxoplasmosis_Homo sapiens_hsa051450.92989774
56Taste transduction_Homo sapiens_hsa047420.92900719
57ABC transporters_Homo sapiens_hsa020100.92582038
58Small cell lung cancer_Homo sapiens_hsa052220.90959977
59Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.89946560
60Sulfur relay system_Homo sapiens_hsa041220.89857477
61Circadian entrainment_Homo sapiens_hsa047130.87353293
62GABAergic synapse_Homo sapiens_hsa047270.84574264
63Fat digestion and absorption_Homo sapiens_hsa049750.83668962
64Insulin secretion_Homo sapiens_hsa049110.81358319
65African trypanosomiasis_Homo sapiens_hsa051430.81333802
66Oxidative phosphorylation_Homo sapiens_hsa001900.80687608
67Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.80431150
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75395554
69Hematopoietic cell lineage_Homo sapiens_hsa046400.74203847
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.74087167
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73452475
72Glucagon signaling pathway_Homo sapiens_hsa049220.72543506
73Oxytocin signaling pathway_Homo sapiens_hsa049210.72012405
74Ovarian steroidogenesis_Homo sapiens_hsa049130.71132357
75Amoebiasis_Homo sapiens_hsa051460.69641570
76Insulin signaling pathway_Homo sapiens_hsa049100.67337180
77Alzheimers disease_Homo sapiens_hsa050100.67177774
78Phenylalanine metabolism_Homo sapiens_hsa003600.66089339
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65836576
80Cyanoamino acid metabolism_Homo sapiens_hsa004600.64749969
81Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64603248
82Arachidonic acid metabolism_Homo sapiens_hsa005900.63964205
83PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63368418
84Arginine biosynthesis_Homo sapiens_hsa002200.63029378
85Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.62964349
86Renin secretion_Homo sapiens_hsa049240.62469520
87Maturity onset diabetes of the young_Homo sapiens_hsa049500.61484004
88One carbon pool by folate_Homo sapiens_hsa006700.60572669
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60370941
90AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59958727
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59266653
92HIF-1 signaling pathway_Homo sapiens_hsa040660.58546677
93Serotonergic synapse_Homo sapiens_hsa047260.58262382
94Dorso-ventral axis formation_Homo sapiens_hsa043200.56739909
95Glutamatergic synapse_Homo sapiens_hsa047240.55285168
96Platelet activation_Homo sapiens_hsa046110.55060922
97Measles_Homo sapiens_hsa051620.54464481
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54371729
99Vascular smooth muscle contraction_Homo sapiens_hsa042700.54006505
100Complement and coagulation cascades_Homo sapiens_hsa046100.52108732
101Bile secretion_Homo sapiens_hsa049760.51573419
102cAMP signaling pathway_Homo sapiens_hsa040240.50383963
103Steroid hormone biosynthesis_Homo sapiens_hsa001400.49964577
104Protein digestion and absorption_Homo sapiens_hsa049740.49761553
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.48747065
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47465678
107Rap1 signaling pathway_Homo sapiens_hsa040150.47208901
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.46963448
109Huntingtons disease_Homo sapiens_hsa050160.46001610
110Toll-like receptor signaling pathway_Homo sapiens_hsa046200.45893465
111Tyrosine metabolism_Homo sapiens_hsa003500.44544564
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.44382404
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44288308
114Salivary secretion_Homo sapiens_hsa049700.43550110
115Staphylococcus aureus infection_Homo sapiens_hsa051500.42830041
116Leishmaniasis_Homo sapiens_hsa051400.42305192
117Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.42133889
118Type II diabetes mellitus_Homo sapiens_hsa049300.41087547
119NF-kappa B signaling pathway_Homo sapiens_hsa040640.40774058
120Notch signaling pathway_Homo sapiens_hsa043300.39271314
121Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.36895791
122Intestinal immune network for IgA production_Homo sapiens_hsa046720.35920895
123Gastric acid secretion_Homo sapiens_hsa049710.35901966
124Cocaine addiction_Homo sapiens_hsa050300.35658096
125Circadian rhythm_Homo sapiens_hsa047100.34856239
126Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.34487017
127Amphetamine addiction_Homo sapiens_hsa050310.34332610
128Calcium signaling pathway_Homo sapiens_hsa040200.34076183
129Autoimmune thyroid disease_Homo sapiens_hsa053200.33800510
130Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33762406
131Osteoclast differentiation_Homo sapiens_hsa043800.32612193
132Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.31669925
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30147702
134TNF signaling pathway_Homo sapiens_hsa046680.30020971
135Influenza A_Homo sapiens_hsa051640.29853611
136Pathways in cancer_Homo sapiens_hsa052000.23974299
137FoxO signaling pathway_Homo sapiens_hsa040680.23463547
138Galactose metabolism_Homo sapiens_hsa000520.23292904
139Ras signaling pathway_Homo sapiens_hsa040140.22446413
140Arginine and proline metabolism_Homo sapiens_hsa003300.21633700
141Vitamin digestion and absorption_Homo sapiens_hsa049770.19825746
142RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19284970
143Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.18542743
144Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.18526263

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