BTNL10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1oxygen transport (GO:0015671)8.25452165
2doxorubicin metabolic process (GO:0044598)7.78621068
3daunorubicin metabolic process (GO:0044597)7.78621068
4polyketide metabolic process (GO:0030638)7.78621068
5mating behavior (GO:0007617)7.73905792
6gas transport (GO:0015669)7.31560335
7Arp2/3 complex-mediated actin nucleation (GO:0034314)7.04656981
8actin nucleation (GO:0045010)6.44456362
9porphyrin-containing compound metabolic process (GO:0006778)6.19396528
10positive regulation of gamma-delta T cell activation (GO:0046645)6.15759614
11heme metabolic process (GO:0042168)5.59363165
12detection of molecule of bacterial origin (GO:0032490)5.41112398
13genitalia morphogenesis (GO:0035112)5.26309365
14regulation of gamma-delta T cell differentiation (GO:0045586)5.16336236
15positive regulation of cGMP biosynthetic process (GO:0030828)4.97091405
16response to methylmercury (GO:0051597)4.89639555
17phosphatidylethanolamine metabolic process (GO:0046337)4.80411688
18positive regulation of cellular amide metabolic process (GO:0034250)4.76558160
19aminoglycoside antibiotic metabolic process (GO:0030647)4.75264637
20regulation of cGMP biosynthetic process (GO:0030826)4.68714634
21regulation of gamma-delta T cell activation (GO:0046643)4.62945098
22superoxide anion generation (GO:0042554)4.52992968
23regulation of activation of Janus kinase activity (GO:0010533)4.35398112
24protoporphyrinogen IX metabolic process (GO:0046501)4.27656291
25positive regulation of cGMP metabolic process (GO:0030825)4.24425223
26regulation of natural killer cell differentiation (GO:0032823)4.23621105
27positive regulation of heat generation (GO:0031652)4.18017504
28protoporphyrinogen IX biosynthetic process (GO:0006782)4.07501792
29glycine transport (GO:0015816)3.96499911
30detection of external biotic stimulus (GO:0098581)3.95488406
31regulation of fever generation (GO:0031620)3.95060817
32histone H3-K9 modification (GO:0061647)3.89104332
33regulation of cGMP metabolic process (GO:0030823)3.88212698
34phosphatidylethanolamine biosynthetic process (GO:0006646)3.86669728
35energy homeostasis (GO:0097009)3.84694705
36negative regulation of mast cell activation (GO:0033004)3.81722799
37response to pheromone (GO:0019236)3.78752340
38phosphorelay signal transduction system (GO:0000160)3.77090787
39myeloid cell development (GO:0061515)3.76878361
40regulation of interferon-beta biosynthetic process (GO:0045357)3.73282927
41homeostasis of number of cells within a tissue (GO:0048873)3.69764306
42tetrapyrrole metabolic process (GO:0033013)3.64359601
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.63953787
44modulation by symbiont of host immune response (GO:0052553)3.56021846
45positive regulation by symbiont of host defense response (GO:0052509)3.56021846
46modulation by symbiont of host defense response (GO:0052031)3.56021846
47modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.56021846
48modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.56021846
49positive regulation by organism of defense response of other organism involved in symbiotic interact3.56021846
50interferon-gamma production (GO:0032609)3.55516349
51sulfate transmembrane transport (GO:1902358)3.51836802
52myoblast migration (GO:0051451)3.48124175
53cellular response to dexamethasone stimulus (GO:0071549)3.47734180
54histone H3-K9 methylation (GO:0051567)3.44763579
55cytidine deamination (GO:0009972)3.44484391
56cytidine metabolic process (GO:0046087)3.44484391
57cytidine catabolic process (GO:0006216)3.44484391
58detection of biotic stimulus (GO:0009595)3.40826120
59response to peptidoglycan (GO:0032494)3.40296130
60auditory receptor cell stereocilium organization (GO:0060088)3.37527885
61sulfate transport (GO:0008272)3.33847161
62positive regulation of granulocyte differentiation (GO:0030854)3.28192745
63regulation of viral entry into host cell (GO:0046596)3.27514695
64negative regulation of viral entry into host cell (GO:0046597)3.22705319
65cellular response to virus (GO:0098586)3.20553377
66response to insecticide (GO:0017085)3.19978802
67negative T cell selection (GO:0043383)3.19567684
68response to dexamethasone (GO:0071548)3.18795641
69positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.18702571
70glycerol metabolic process (GO:0006071)3.16093522
71positive regulation of gluconeogenesis (GO:0045722)3.15853912
72positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.15023863
73regulation of heat generation (GO:0031650)3.11895061
74seminiferous tubule development (GO:0072520)3.10749133
75positive regulation of interleukin-1 secretion (GO:0050716)3.09412262
76positive regulation of B cell differentiation (GO:0045579)3.08478027
77spermatid development (GO:0007286)3.08271775
78positive regulation of interleukin-1 beta secretion (GO:0050718)3.07363841
79positive T cell selection (GO:0043368)3.06952881
80positive regulation of chemokine biosynthetic process (GO:0045080)3.06885659
81response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.03889105
82response to host immune response (GO:0052572)3.03889105
83regulation of double-strand break repair via homologous recombination (GO:0010569)3.03394652
84regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.03344494
85N-terminal protein amino acid acetylation (GO:0006474)3.02657909
86regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.01708948
87positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.01708948
88negative regulation of viral genome replication (GO:0045071)2.99845575
89macrophage activation (GO:0042116)2.99412617
90regulation of interleukin-6 biosynthetic process (GO:0045408)2.97624590
91G-protein coupled receptor internalization (GO:0002031)2.95630176
92neutrophil activation involved in immune response (GO:0002283)2.95584847
93bicarbonate transport (GO:0015701)2.94624591
94microglial cell activation (GO:0001774)2.92550194
95neutrophil activation (GO:0042119)2.90115303
96regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.87826593
97resolution of meiotic recombination intermediates (GO:0000712)2.87700212
98lipopolysaccharide-mediated signaling pathway (GO:0031663)2.85767208
99positive regulation of natural killer cell differentiation (GO:0032825)2.85321786
100pyrimidine ribonucleoside catabolic process (GO:0046133)2.85171581
101regulation of interleukin-1 beta secretion (GO:0050706)2.85162519
102fertilization (GO:0009566)2.84940579
103response to arsenic-containing substance (GO:0046685)2.84855493
104cellular response to arsenic-containing substance (GO:0071243)2.84831234
105regulation of chemokine biosynthetic process (GO:0045073)2.84436043
106granulocyte activation (GO:0036230)2.84237243
107regulation of response to osmotic stress (GO:0047484)2.83264371
108tetrapyrrole biosynthetic process (GO:0033014)2.82460426
109regulation of natural killer cell activation (GO:0032814)2.82059227
110response to lead ion (GO:0010288)2.80221717
111positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.80178025
112synapsis (GO:0007129)2.80169103
113erythrocyte maturation (GO:0043249)2.80071041
114alditol metabolic process (GO:0019400)2.79903576
115embryonic hemopoiesis (GO:0035162)2.79846759
116negative regulation of erythrocyte differentiation (GO:0045647)2.78931845
117monocyte chemotaxis (GO:0002548)2.77757712
118protein import into peroxisome matrix (GO:0016558)2.76851316
119protein-cofactor linkage (GO:0018065)2.76338376
120positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.76133288
121positive regulation of type 2 immune response (GO:0002830)2.75841141
122cellular anion homeostasis (GO:0030002)2.75343736
123porphyrin-containing compound biosynthetic process (GO:0006779)2.75019886
124superoxide metabolic process (GO:0006801)2.74214055
125detection of other organism (GO:0098543)2.73187292
126production of molecular mediator involved in inflammatory response (GO:0002532)2.72420981
127natural killer cell activation involved in immune response (GO:0002323)2.70204723
128negative regulation of interleukin-12 production (GO:0032695)2.68930415
129regulation of lamellipodium assembly (GO:0010591)2.68128451
130innate immune response in mucosa (GO:0002227)2.66454929
131protein targeting to Golgi (GO:0000042)2.66319426
132regulation of B cell receptor signaling pathway (GO:0050855)2.65412147
133multicellular organism reproduction (GO:0032504)2.65083161
134dendritic cell chemotaxis (GO:0002407)2.62511562
135regulation of mast cell degranulation (GO:0043304)2.62245467
136negative regulation of execution phase of apoptosis (GO:1900118)2.61660265
137leukocyte aggregation (GO:0070486)2.60643745
138one-carbon compound transport (GO:0019755)2.60423183
139positive regulation of megakaryocyte differentiation (GO:0045654)2.60375143
140regulation of mast cell activation (GO:0033003)2.60061346
141regulation of vitamin D biosynthetic process (GO:0060556)2.59179503
142erythrocyte differentiation (GO:0030218)2.58814480
143response to host (GO:0075136)2.58233300
144response to host defenses (GO:0052200)2.58233300
145response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.58233300
146erythrocyte development (GO:0048821)2.57984819
147establishment of protein localization to Golgi (GO:0072600)2.57502817
148hemoglobin metabolic process (GO:0020027)2.56812539
149mitochondrion degradation (GO:0000422)2.56645852
150regulation of mononuclear cell migration (GO:0071675)2.56527675
151positive regulation of interleukin-17 production (GO:0032740)2.56155721
152regulation of interleukin-1 secretion (GO:0050704)2.54527942
153positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.53905482
154heme biosynthetic process (GO:0006783)2.53817841
155regulation of vitamin metabolic process (GO:0030656)2.53743012
156regulation of mast cell activation involved in immune response (GO:0033006)2.53364214
157regulation of DNA endoreduplication (GO:0032875)2.53354049
158inner ear receptor stereocilium organization (GO:0060122)2.52794818
159platelet formation (GO:0030220)2.52082115
160positive regulation of mast cell activation involved in immune response (GO:0033008)2.51994137
161positive regulation of mast cell degranulation (GO:0043306)2.51994137
162positive regulation of interleukin-10 production (GO:0032733)2.51780399
163positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.51451571
164cellular response to exogenous dsRNA (GO:0071360)2.51161819
165deoxyribose phosphate biosynthetic process (GO:0046385)2.50191493
1662-deoxyribonucleotide biosynthetic process (GO:0009265)2.50191493
167cytolysis (GO:0019835)2.49361565
168regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.48875860
169positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.48875860
170modulation by virus of host process (GO:0019054)2.48854403
171acrosome reaction (GO:0007340)2.48221348
172regulation of platelet aggregation (GO:0090330)2.48138829
173cellular zinc ion homeostasis (GO:0006882)2.47876674
174detection of bacterium (GO:0016045)2.47369829
175positive regulation of natural killer cell activation (GO:0032816)2.47230564
176positive regulation of lymphocyte migration (GO:2000403)2.46835981
177sperm motility (GO:0030317)2.46758117
178positive regulation of interleukin-6 production (GO:0032755)2.46756478
179regulation of interferon-gamma biosynthetic process (GO:0045072)2.45536655
180positive regulation of prostaglandin secretion (GO:0032308)2.44300689
181defense response to protozoan (GO:0042832)2.43554009
182positive regulation of male gonad development (GO:2000020)2.43131231
183regulation of male gonad development (GO:2000018)2.42757889
184drinking behavior (GO:0042756)2.42531768
185eosinophil chemotaxis (GO:0048245)2.41971170
186negative regulation of meiosis (GO:0045835)2.41674105
187response to type I interferon (GO:0034340)2.40692789

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.94052376
2GATA1_19941826_ChIP-Seq_K562_Human5.16783021
3RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.16744674
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.80204911
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.68168570
6GBX2_23144817_ChIP-Seq_PC3_Human3.41423796
7IRF8_22096565_ChIP-ChIP_GC-B_Human3.27926274
8GATA2_19941826_ChIP-Seq_K562_Human3.17755270
9SALL1_21062744_ChIP-ChIP_HESCs_Human3.04442727
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.92595709
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.91883297
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.59321626
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.42613065
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.37457443
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.21290165
16TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse2.20985361
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.20873920
18MYB_26560356_Chip-Seq_TH2_Human2.19082984
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.17853159
20NFE2_27457419_Chip-Seq_LIVER_Mouse2.17226530
21EZH2_22144423_ChIP-Seq_EOC_Human2.15627353
22SUZ12_27294783_Chip-Seq_NPCs_Mouse2.12896946
23FOXM1_23109430_ChIP-Seq_U2OS_Human2.12021247
24RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.11086812
25IRF8_27001747_Chip-Seq_BMDM_Mouse2.01650610
26GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.96151849
27PCGF2_27294783_Chip-Seq_NPCs_Mouse1.92873300
28MAF_26560356_Chip-Seq_TH1_Human1.91781599
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91097983
30EZH2_27294783_Chip-Seq_NPCs_Mouse1.89742391
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.89200173
32EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.88250825
33SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.86920334
34IGF1R_20145208_ChIP-Seq_DFB_Human1.82734849
35SCL_19346495_ChIP-Seq_HPC-7_Human1.76962239
36MYB_26560356_Chip-Seq_TH1_Human1.76310327
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.76277302
38STAT3_18555785_Chip-Seq_ESCs_Mouse1.76082782
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.75939439
40SUZ12_18555785_Chip-Seq_ESCs_Mouse1.75764395
41E2F1_18555785_Chip-Seq_ESCs_Mouse1.75561433
42UTX_26944678_Chip-Seq_JUKART_Human1.75298475
43P53_22387025_ChIP-Seq_ESCs_Mouse1.74011698
44VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73386964
45TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.73235226
46NANOG_18555785_Chip-Seq_ESCs_Mouse1.72813792
47EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.72738340
48IKZF1_21737484_ChIP-ChIP_HCT116_Human1.72504796
49KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.72038165
50NANOG_20526341_ChIP-Seq_ESCs_Human1.71675761
51GATA1_22383799_ChIP-Seq_G1ME_Mouse1.71093220
52Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.70423390
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.67871134
54MAF_26560356_Chip-Seq_TH2_Human1.66119472
55NMYC_18555785_Chip-Seq_ESCs_Mouse1.62589108
56LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.62365443
57P300_19829295_ChIP-Seq_ESCs_Human1.62155307
58SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.59889792
59EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.59784214
60RNF2_27304074_Chip-Seq_NSC_Mouse1.59034732
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.58467814
62SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56652251
63STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.56226849
64CMYC_18555785_Chip-Seq_ESCs_Mouse1.56073340
65RUNX1_27457419_Chip-Seq_LIVER_Mouse1.55173771
66GATA1_22025678_ChIP-Seq_K562_Human1.54180671
67OCT4_18555785_Chip-Seq_ESCs_Mouse1.53602675
68SPI1_23127762_ChIP-Seq_K562_Human1.52656056
69FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.51428309
70GATA3_26560356_Chip-Seq_TH2_Human1.49981071
71PU1_27457419_Chip-Seq_LIVER_Mouse1.49914001
72E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.49211435
73TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47214431
74P300_18555785_Chip-Seq_ESCs_Mouse1.47169631
75EED_16625203_ChIP-ChIP_MESCs_Mouse1.45817568
76GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45770137
77SOX2_18555785_Chip-Seq_ESCs_Mouse1.44966385
78ZFX_18555785_Chip-Seq_ESCs_Mouse1.43781790
79CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43735546
80TP53_22573176_ChIP-Seq_HFKS_Human1.43565724
81ESRRB_18555785_Chip-Seq_ESCs_Mouse1.42041983
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41581068
83TP63_19390658_ChIP-ChIP_HaCaT_Human1.40245471
84SMAD1_18555785_Chip-Seq_ESCs_Mouse1.35960953
85HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.35552246
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.35125953
87ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.35097012
88BCL6_27268052_Chip-Seq_Bcells_Human1.33838565
89KLF4_18555785_Chip-Seq_ESCs_Mouse1.33360141
90CTCF_18555785_Chip-Seq_ESCs_Mouse1.32954771
91BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.31687096
92MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29513987
93CTCF_27219007_Chip-Seq_ERYTHROID_Human1.28372359
94JARID2_20064375_ChIP-Seq_MESCs_Mouse1.27626201
95WDR5_24793694_ChIP-Seq_LNCAP_Human1.26600175
96CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24990450
97SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.24918870
98SPI1_23547873_ChIP-Seq_NB4_Human1.24723072
99ER_23166858_ChIP-Seq_MCF-7_Human1.24525197
100NCOR1_26117541_ChIP-Seq_K562_Human1.24444848
101PIAS1_25552417_ChIP-Seq_VCAP_Human1.23815135
102STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.23504237
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23388333
104GATA3_26560356_Chip-Seq_TH1_Human1.23243643
105CTCF_21964334_ChIP-Seq_BJAB-B_Human1.22816354
106STAT6_21828071_ChIP-Seq_BEAS2B_Human1.22737271
107GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.22283358
108OCT4_21477851_ChIP-Seq_ESCs_Mouse1.21736572
109GATA3_27048872_Chip-Seq_THYMUS_Human1.20518293
110CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.19503076
111VDR_21846776_ChIP-Seq_THP-1_Human1.19332174
112LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17334892
113FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.17214259
114GATA1_19941827_ChIP-Seq_MEL_Mouse1.17085138
115SRF_21415370_ChIP-Seq_HL-1_Mouse1.15965846
116CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15502552
117RUNX1_22412390_ChIP-Seq_EML_Mouse1.15356261
118GATA2_22383799_ChIP-Seq_G1ME_Mouse1.15290717
119SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.14551164
120GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14207205
121SMAD4_21799915_ChIP-Seq_A2780_Human1.14205322
122RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.13810324
123VDR_22108803_ChIP-Seq_LS180_Human1.13532610
124MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.13401568
125CRX_20693478_ChIP-Seq_RETINA_Mouse1.13338814
126EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.13063916
127TAL1_26923725_Chip-Seq_HPCs_Mouse1.12813591
128SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.12420345
129SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.11470824
130EWS_26573619_Chip-Seq_HEK293_Human1.10819453
131SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.10503993
132SA1_27219007_Chip-Seq_Bcells_Human1.10496785
133PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10393071
134PHF8_20622854_ChIP-Seq_HELA_Human1.10233815
135NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10205060
136NCOR_22424771_ChIP-Seq_293T_Human1.09850899
137YY1_22570637_ChIP-Seq_MALME-3M_Human1.09574756
138E2F7_22180533_ChIP-Seq_HELA_Human1.09529242
139TAF2_19829295_ChIP-Seq_ESCs_Human1.09155660
140SMAD3_21741376_ChIP-Seq_EPCs_Human1.09131267
141EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.08819535
142SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.08805752
143AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07825930
144CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07823293
145VDR_24787735_ChIP-Seq_THP-1_Human1.07149815
146BCOR_27268052_Chip-Seq_Bcells_Human1.06745055
147EGR1_23403033_ChIP-Seq_LIVER_Mouse1.06035057
148BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.05869741
149STAT4_19710469_ChIP-ChIP_TH1__Mouse1.05451509
150PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05201913
151EZH2_27304074_Chip-Seq_ESCs_Mouse1.04759527
152ERG_20517297_ChIP-Seq_VCAP_Human1.04272170
153TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04059802
154POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04059802
155TCF4_23295773_ChIP-Seq_U87_Human1.03786376
156KDM2B_26808549_Chip-Seq_REH_Human1.03642646
157FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.02108543
158RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.01178033
159VDR_24763502_ChIP-Seq_THP-1_Human1.00937919
160AR_25329375_ChIP-Seq_VCAP_Human0.98834222
161STAT1_20625510_ChIP-Seq_HELA_Human0.98588906
162SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.98551452
163TDRD3_21172665_ChIP-Seq_MCF-7_Human0.97999909
164CTCF_20526341_ChIP-Seq_ESCs_Human0.97504134
165CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.97407447
166SA1_27219007_Chip-Seq_ERYTHROID_Human0.95959821
167RAD21_21589869_ChIP-Seq_MESCs_Mouse0.94862080
168P300_27268052_Chip-Seq_Bcells_Human0.93057971
169MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.91731971
170CTCF_21964334_Chip-Seq_Bcells_Human0.91000443
171ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88187251
172PPARA_22158963_ChIP-Seq_LIVER_Mouse0.87575421
173HOXB7_26014856_ChIP-Seq_BT474_Human0.86371431
174SALL4_22934838_ChIP-ChIP_CD34+_Human0.86147725
175OCT4_19829295_ChIP-Seq_ESCs_Human0.85944900
176VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.85233558
177SPI1_20517297_ChIP-Seq_HL60_Human0.84673743
178CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83422654
179RAC3_21632823_ChIP-Seq_H3396_Human0.82636829

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot3.84535904
2MP0003878_abnormal_ear_physiology3.84535904
3MP0004147_increased_porphyrin_level3.47742768
4MP0005645_abnormal_hypothalamus_physiol3.03469213
5MP0003656_abnormal_erythrocyte_physiolo2.95748444
6MP0006292_abnormal_olfactory_placode2.93941679
7MP0001835_abnormal_antigen_presentation2.90899221
8MP0002277_abnormal_respiratory_mucosa2.83346448
9MP0005083_abnormal_biliary_tract2.81824753
10MP0002166_altered_tumor_susceptibility2.60609710
11MP0002009_preneoplasia2.58611023
12MP0002148_abnormal_hypersensitivity_rea2.55678586
13MP0009785_altered_susceptibility_to2.45857842
14MP0008004_abnormal_stomach_pH2.41773113
15MP0005075_abnormal_melanosome_morpholog2.37287855
16MP0005671_abnormal_response_to2.32627758
17MP0000566_synostosis2.29421599
18MP0009697_abnormal_copulation2.18517568
19MP0001986_abnormal_taste_sensitivity2.15716511
20MP0003436_decreased_susceptibility_to2.08543504
21MP0002419_abnormal_innate_immunity2.00463781
22MP0008995_early_reproductive_senescence1.95328069
23MP0008260_abnormal_autophagy1.95232639
24MP0008007_abnormal_cellular_replicative1.94462042
25MP0006082_CNS_inflammation1.93547472
26MP0002132_abnormal_respiratory_system1.91847049
27MP0005646_abnormal_pituitary_gland1.90912361
28MP0003941_abnormal_skin_development1.90490228
29MP0005000_abnormal_immune_tolerance1.89309690
30MP0009764_decreased_sensitivity_to1.88848308
31MP0005387_immune_system_phenotype1.87864174
32MP0001790_abnormal_immune_system1.87864174
33MP0001188_hyperpigmentation1.80463882
34MP0005025_abnormal_response_to1.79028406
35MP0003806_abnormal_nucleotide_metabolis1.77370877
36MP0005410_abnormal_fertilization1.75424920
37MP0004381_abnormal_hair_follicle1.73897360
38MP0003879_abnormal_hair_cell1.70229529
39MP0005171_absent_coat_pigmentation1.69882908
40MP0004742_abnormal_vestibular_system1.65515807
41MP0004782_abnormal_surfactant_physiolog1.64419920
42MP0002452_abnormal_antigen_presenting1.62154609
43MP0003786_premature_aging1.56640937
44MP0005636_abnormal_mineral_homeostasis1.56144329
45MP0003763_abnormal_thymus_physiology1.53489956
46MP0002163_abnormal_gland_morphology1.51768862
47MP0002735_abnormal_chemical_nociception1.49587586
48MP0002723_abnormal_immune_serum1.48209249
49MP0001819_abnormal_immune_cell1.45129877
50MP0003724_increased_susceptibility_to1.44680419
51MP0002736_abnormal_nociception_after1.44634359
52MP0001800_abnormal_humoral_immune1.43162080
53MP0005257_abnormal_intraocular_pressure1.42476055
54MP0002396_abnormal_hematopoietic_system1.42100359
55MP0010386_abnormal_urinary_bladder1.41546340
56MP0002420_abnormal_adaptive_immunity1.40773574
57MP0004510_myositis1.40571908
58MP0000685_abnormal_immune_system1.39584332
59MP0002102_abnormal_ear_morphology1.38546135
60MP0005310_abnormal_salivary_gland1.37656182
61MP0005647_abnormal_sex_gland1.32039525
62MP0000678_abnormal_parathyroid_gland1.31341091
63MP0003172_abnormal_lysosome_physiology1.30639683
64MP0008877_abnormal_DNA_methylation1.29710947
65MP0005464_abnormal_platelet_physiology1.25099368
66MP0003787_abnormal_imprinting1.24913304
67MP0002998_abnormal_bone_remodeling1.22150378
68MP0000703_abnormal_thymus_morphology1.21856861
69MP0005174_abnormal_tail_pigmentation1.21365795
70MP0000015_abnormal_ear_pigmentation1.19399637
71MP0003111_abnormal_nucleus_morphology1.17695120
72MP0000569_abnormal_digit_pigmentation1.14851615
73MP0001346_abnormal_lacrimal_gland1.14551206
74MP0002398_abnormal_bone_marrow1.13991560
75MP0010094_abnormal_chromosome_stability1.10558739
76MP0003698_abnormal_male_reproductive1.09593628
77MP0008058_abnormal_DNA_repair1.07138878
78MP0010307_abnormal_tumor_latency1.06917106
79MP0008872_abnormal_physiological_respon1.06679032
80MP0002254_reproductive_system_inflammat1.06320611
81MP0000371_diluted_coat_color1.05773580
82MP0000609_abnormal_liver_physiology1.05558119
83MP0002332_abnormal_exercise_endurance1.03049070
84MP0000716_abnormal_immune_system1.02113930
85MP0001929_abnormal_gametogenesis1.01659647
86MP0001119_abnormal_female_reproductive0.97583574
87MP0008057_abnormal_DNA_replication0.95563677
88MP0002019_abnormal_tumor_incidence0.94943268
89MP0001845_abnormal_inflammatory_respons0.93107802
90MP0002429_abnormal_blood_cell0.92122651
91MP0005397_hematopoietic_system_phenotyp0.89735594
92MP0001545_abnormal_hematopoietic_system0.89735594
93MP0000681_abnormal_thyroid_gland0.89717368
94MP0001919_abnormal_reproductive_system0.88788001
95MP0002638_abnormal_pupillary_reflex0.87858914
96MP0002653_abnormal_ependyma_morphology0.87209676
97MP0001533_abnormal_skeleton_physiology0.86723497
98MP0002405_respiratory_system_inflammati0.86709277
99MP0005379_endocrine/exocrine_gland_phen0.84619092
100MP0002210_abnormal_sex_determination0.84617633
101MP0002938_white_spotting0.84595935
102MP0008961_abnormal_basal_metabolism0.84410673
103MP0002693_abnormal_pancreas_physiology0.84314829
104MP0001968_abnormal_touch/_nociception0.83972942
105MP0002138_abnormal_hepatobiliary_system0.83820546
106MP0009333_abnormal_splenocyte_physiolog0.83354937
107MP0006276_abnormal_autonomic_nervous0.81945009
108MP0002837_dystrophic_cardiac_calcinosis0.80020075
109MP0003866_abnormal_defecation0.79528318
110MP0009278_abnormal_bone_marrow0.79228568
111MP0000372_irregular_coat_pigmentation0.77021590
112MP0003303_peritoneal_inflammation0.76851649
113MP0005266_abnormal_metabolism0.76236627
114MP0000490_abnormal_crypts_of0.76104146
115MP0002876_abnormal_thyroid_physiology0.76029979
116MP0001502_abnormal_circadian_rhythm0.75107532
117MP0001873_stomach_inflammation0.74892671
118MP0005389_reproductive_system_phenotype0.74771505
119MP0001764_abnormal_homeostasis0.74571367
120MP0008469_abnormal_protein_level0.73244378
121MP0009763_increased_sensitivity_to0.72998438
122MP0005670_abnormal_white_adipose0.71062735
123MP0002006_tumorigenesis0.70762889
124MP0010155_abnormal_intestine_physiology0.70721400
125MP0002095_abnormal_skin_pigmentation0.70419695
126MP0000689_abnormal_spleen_morphology0.69888175
127MP0005167_abnormal_blood-brain_barrier0.69505848
128MP0000470_abnormal_stomach_morphology0.67572644
129MP0001529_abnormal_vocalization0.67246165
130MP0002722_abnormal_immune_system0.66944949
131MP0001145_abnormal_male_reproductive0.66097197
132MP0003077_abnormal_cell_cycle0.65603563
133MP0001963_abnormal_hearing_physiology0.64465967
134MP0002098_abnormal_vibrissa_morphology0.64103452
135MP0003045_fibrosis0.64054780
136MP0000026_abnormal_inner_ear0.63897547
137MP0004808_abnormal_hematopoietic_stem0.63013711
138MP0006036_abnormal_mitochondrial_physio0.63011797
139MP0001501_abnormal_sleep_pattern0.62098567
140MP0001243_abnormal_dermal_layer0.62021308
141MP0004130_abnormal_muscle_cell0.61871721
142MP0003795_abnormal_bone_structure0.61197155
143MP0001663_abnormal_digestive_system0.60969363
144MP0001944_abnormal_pancreas_morphology0.60852394

Predicted human phenotypes

RankGene SetZ-score
1Microcytic anemia (HP:0001935)5.52118417
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.38087439
3Prostate neoplasm (HP:0100787)5.07854431
4Cholelithiasis (HP:0001081)4.99675192
5Chromsome breakage (HP:0040012)4.79166000
6Hypochromic anemia (HP:0001931)4.74603708
7Abnormal gallbladder morphology (HP:0012437)4.67353774
8Severe visual impairment (HP:0001141)4.24220369
9Osteomalacia (HP:0002749)4.04656487
10Paralysis (HP:0003470)3.96105718
11Abnormal hemoglobin (HP:0011902)3.84502403
12Abnormality of the heme biosynthetic pathway (HP:0010472)3.83021389
13Cheilitis (HP:0100825)3.75870944
14Unilateral renal agenesis (HP:0000122)3.75186900
15Poikilocytosis (HP:0004447)3.60045956
16Autoimmune hemolytic anemia (HP:0001890)3.52603910
17Parakeratosis (HP:0001036)3.48211790
18Eczematoid dermatitis (HP:0000976)3.43860970
19Recurrent abscess formation (HP:0002722)3.43533863
20Abnormality of reticulocytes (HP:0004312)3.27830730
21Abnormality of the gallbladder (HP:0005264)3.25929565
22Ileus (HP:0002595)3.20482282
23Abnormality of B cell number (HP:0010975)3.19714606
24Polycythemia (HP:0001901)3.16902754
25Dynein arm defect of respiratory motile cilia (HP:0012255)3.13912985
26Absent/shortened dynein arms (HP:0200106)3.13912985
27Orthostatic hypotension (HP:0001278)3.09578348
28Retrobulbar optic neuritis (HP:0100654)2.98955419
29Optic neuritis (HP:0100653)2.98955419
30Recurrent gram-negative bacterial infections (HP:0005420)2.97285734
31Albinism (HP:0001022)2.94393332
32Mediastinal lymphadenopathy (HP:0100721)2.92879126
33Increased IgE level (HP:0003212)2.92301431
34Clubbing of toes (HP:0100760)2.85632015
35Hyperbilirubinemia (HP:0002904)2.79526455
36Abnormality of the prostate (HP:0008775)2.74330998
37Posterior subcapsular cataract (HP:0007787)2.74220579
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.72727354
39Duplicated collecting system (HP:0000081)2.71802773
40Septo-optic dysplasia (HP:0100842)2.71229209
41Abnormality of the renal collecting system (HP:0004742)2.67740469
42Recurrent bacterial skin infections (HP:0005406)2.66073775
43Alopecia of scalp (HP:0002293)2.60270816
44Infertility (HP:0000789)2.59342448
45Eosinophilia (HP:0001880)2.55590530
46Chronic mucocutaneous candidiasis (HP:0002728)2.54276492
47Recurrent cutaneous fungal infections (HP:0011370)2.54276492
48Abnormal rod and cone electroretinograms (HP:0008323)2.54250768
49Chronic hepatic failure (HP:0100626)2.53397044
50Increased IgM level (HP:0003496)2.51769999
51Ectopic kidney (HP:0000086)2.51284794
52Abnormality of dental color (HP:0011073)2.48918271
53Abnormality of male internal genitalia (HP:0000022)2.47817719
54Abnormality of DNA repair (HP:0003254)2.47721569
55Abnormality of the preputium (HP:0100587)2.45523337
56Toxemia of pregnancy (HP:0100603)2.45341013
57Abnormality of the fingertips (HP:0001211)2.44417272
58Granulocytopenia (HP:0001913)2.43229391
59Recurrent fungal infections (HP:0002841)2.43020503
60Urticaria (HP:0001025)2.41190131
61Absent eyebrow (HP:0002223)2.40444790
62Congenital sensorineural hearing impairment (HP:0008527)2.39510564
63Abnormality of iron homeostasis (HP:0011031)2.39495853
64Diaphragmatic weakness (HP:0009113)2.39029991
65Recurrent pneumonia (HP:0006532)2.38753467
66Obstructive lung disease (HP:0006536)2.36838728
67Chronic obstructive pulmonary disease (HP:0006510)2.36838728
68Orchitis (HP:0100796)2.36248685
69Ectropion (HP:0000656)2.35849653
70B lymphocytopenia (HP:0010976)2.34452319
71Dyschromatopsia (HP:0007641)2.29712442
72High pitched voice (HP:0001620)2.29536111
73Abnormal gallbladder physiology (HP:0012438)2.28595973
74Cholecystitis (HP:0001082)2.28595973
75Cutaneous photosensitivity (HP:0000992)2.28520792
76Hypoglycemic seizures (HP:0002173)2.27122141
77Meckel diverticulum (HP:0002245)2.27011100
78Lip pit (HP:0100267)2.26706351
79Neonatal hypoglycemia (HP:0001998)2.26399649
80Abnormality of transition element cation homeostasis (HP:0011030)2.26029591
81True hermaphroditism (HP:0010459)2.24638606
82Febrile seizures (HP:0002373)2.24539353
83Follicular hyperkeratosis (HP:0007502)2.24261261
84IgG deficiency (HP:0004315)2.23917055
85Patchy hypopigmentation of hair (HP:0011365)2.22912820
86Gingivitis (HP:0000230)2.22685328
87Alveolar cell carcinoma (HP:0006519)2.22280403
88Chorioretinal atrophy (HP:0000533)2.20605157
89Abnormality of chromosome stability (HP:0003220)2.19665878
90Abnormality of the ileum (HP:0001549)2.19510562
91Decreased central vision (HP:0007663)2.17018664
92Renal Fanconi syndrome (HP:0001994)2.16118012
93Hypochromic microcytic anemia (HP:0004840)2.13939299
94White forelock (HP:0002211)2.12543066
95Prolonged bleeding time (HP:0003010)2.11891718
96Petechiae (HP:0000967)2.10476821
97Abnormality of T cell number (HP:0011839)2.09768108
98Leukocytosis (HP:0001974)2.09436852
99Keratitis (HP:0000491)2.09367294
100Acanthocytosis (HP:0001927)2.08812080
101Abnormality of incisor morphology (HP:0011063)2.08501552
102Chronic otitis media (HP:0000389)2.08435834
103Congenital stationary night blindness (HP:0007642)2.08298949
104Subcapsular cataract (HP:0000523)2.07371760
105Myositis (HP:0100614)2.05369508
106Abnormal ciliary motility (HP:0012262)2.05279477
107Bilateral sensorineural hearing impairment (HP:0008619)2.02817860
108Tetany (HP:0001281)2.01840827
109Hyperphosphatemia (HP:0002905)2.01702797
110Abnormal hair whorl (HP:0010721)2.01304296
111Basal ganglia calcification (HP:0002135)2.01208604
112Vasculitis (HP:0002633)2.00855756
113Recurrent corneal erosions (HP:0000495)1.99792363
114Abnormality of eosinophils (HP:0001879)1.98865428
115Ocular albinism (HP:0001107)1.98012490
116Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.97345805
117Abnormal respiratory epithelium morphology (HP:0012253)1.96018053
118Abnormal respiratory motile cilium morphology (HP:0005938)1.96018053
119Gastrointestinal infarctions (HP:0005244)1.94612714
120Recurrent skin infections (HP:0001581)1.94401145
121Bile duct proliferation (HP:0001408)1.93539985
122Abnormal biliary tract physiology (HP:0012439)1.93539985
123Reticulocytosis (HP:0001923)1.93371372
124Abnormal spermatogenesis (HP:0008669)1.93198644
125Chronic sinusitis (HP:0011109)1.92912873
126Neoplasm of the tracheobronchial system (HP:0100552)1.92501125
127Renal dysplasia (HP:0000110)1.91763452
128Hypophosphatemic rickets (HP:0004912)1.91380129
129Abnormal delayed hypersensitivity skin test (HP:0002963)1.90131871
130Dysautonomia (HP:0002459)1.89584107
131Protruding tongue (HP:0010808)1.89456101
132Pancreatic cysts (HP:0001737)1.88542418
133Premature loss of primary teeth (HP:0006323)1.88489670
134Hypergonadotropic hypogonadism (HP:0000815)1.86041165
135Gingival bleeding (HP:0000225)1.83342442
136Absent rod-and cone-mediated responses on ERG (HP:0007688)1.82789873
137Abnormality of the intervertebral disk (HP:0005108)1.82230398
138IgM deficiency (HP:0002850)1.81442154
139Recurrent lower respiratory tract infections (HP:0002783)1.81352718
140Radial bowing (HP:0002986)1.80812954
141Stomatitis (HP:0010280)1.80601013
142Male infertility (HP:0003251)1.80048683
143Bone marrow hypocellularity (HP:0005528)1.80033965
144Abnormality of the carotid arteries (HP:0005344)1.79688702
145Pustule (HP:0200039)1.79636594
146Male pseudohermaphroditism (HP:0000037)1.79001728
147Pendular nystagmus (HP:0012043)1.77511424
148Abnormality of renal resorption (HP:0011038)1.75573350
149Increased serum ferritin (HP:0003281)1.74574612
150Flat occiput (HP:0005469)1.74405689
151Bone pain (HP:0002653)1.74113111
152Encephalitis (HP:0002383)1.73945697
153Autoimmune thrombocytopenia (HP:0001973)1.72814273
154Conical tooth (HP:0000698)1.71920881
155Pancreatic fibrosis (HP:0100732)1.71908321
156T lymphocytopenia (HP:0005403)1.71716629
157Abnormality of lateral ventricle (HP:0030047)1.71620379
158Cystic liver disease (HP:0006706)1.71204598
159Pulmonary infiltrates (HP:0002113)1.70836457
160Small intestinal stenosis (HP:0012848)1.69508356
161Duodenal stenosis (HP:0100867)1.69508356
162Hyponatremia (HP:0002902)1.69463467
163Optic nerve hypoplasia (HP:0000609)1.69137355
164Pallor (HP:0000980)1.69083836
165Azoospermia (HP:0000027)1.68627114
166Hypoplastic pelvis (HP:0008839)1.68555617
167Short middle phalanx of the 5th finger (HP:0004220)1.67011296
168Exocrine pancreatic insufficiency (HP:0001738)1.66301974
169Iris hypopigmentation (HP:0007730)1.61990066
170Ketosis (HP:0001946)1.61187309
171Brushfield spots (HP:0001088)1.61020392
172Abnormality of T cells (HP:0002843)1.58284340
173Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.57885487
174Abnormality of alanine metabolism (HP:0010916)1.57885487
175Hyperalaninemia (HP:0003348)1.57885487
176Hypoparathyroidism (HP:0000829)1.57432622
177Metaphyseal cupping (HP:0003021)1.57363576

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK35.13198554
2MAP3K143.25559098
3TXK3.23101849
4ZAK3.08762312
5KDR3.06609926
6TAOK12.98575197
7CASK2.94756578
8MAP2K32.84861519
9MAP3K32.60586897
10MAP3K112.51419640
11GRK62.46057907
12PRPF4B2.31273492
13BUB12.28976685
14IRAK42.25425918
15TNIK2.21367362
16MST42.15666156
17IRAK31.98897316
18SIK21.91430088
19CDK121.89342825
20MAP3K11.83510976
21SGK21.75146736
22ADRBK21.68405061
23BMPR21.63422390
24MAP3K51.58231242
25BMPR1B1.57343603
26CDK81.57099712
27IKBKE1.56946778
28YES11.55007886
29RIPK41.54737739
30SCYL21.52125464
31PIK3CA1.50890823
32EIF2AK21.49945938
33IKBKB1.45610512
34STK41.42352729
35BRSK21.37947494
36RPS6KB21.35018132
37FGFR41.32461949
38EPHA31.28535426
39INSRR1.26532857
40MUSK1.25689075
41PTK2B1.24510157
42PBK1.22631829
43MARK31.21672465
44JAK31.20540357
45BRD41.18803316
46PRKCI1.17994420
47NUAK11.17113517
48TNK21.17109255
49PASK1.16303668
50MAPK131.12853798
51VRK11.12772581
52ERBB31.11351310
53GRK71.10693248
54ITK1.10549241
55MST1R1.10528553
56FER1.09084632
57CDK31.07399502
58IRAK11.05501983
59SIK11.05455378
60SGK31.03896463
61PIK3CG1.03206228
62CHUK1.02211766
63KIT1.02095148
64MAP2K11.01508023
65BMX1.00088239
66TEC0.99710098
67MAP2K70.99115839
68STK160.98044114
69SYK0.95128300
70SGK2230.93014031
71SGK4940.93014031
72PIM10.92692532
73TYK20.92366971
74BRSK10.90269635
75JAK10.89335564
76EPHB10.89059424
77TBK10.87050120
78LYN0.84352543
79EEF2K0.83478733
80HIPK20.82087205
81CDK90.82034805
82TRPM70.81721990
83MKNK20.80686940
84IRAK20.79147974
85CLK10.78327201
86RPS6KA50.77896998
87STK30.77290698
88AKT30.76841779
89TIE10.75710951
90DYRK30.75399549
91PAK10.73789066
92JAK20.73321653
93GRK10.71434264
94RPS6KA20.71335295
95STK38L0.70592673
96SRPK10.69268381
97CSK0.68829517
98TAOK20.68633853
99TESK20.68526823
100BRAF0.67735273
101LATS10.67669474
102PINK10.67343599
103TGFBR20.67186067
104ATR0.66036646
105RPS6KL10.65122273
106RPS6KC10.65122273
107RPS6KB10.64983518
108SGK10.64513354
109TLK10.64320330
110MAPK110.64169713
111RET0.63968289
112PRKG20.63163974
113RPS6KA60.62235874
114MAP4K10.60927743
115NEK60.60278590
116ZAP700.59005231
117WNK10.56497580
118BTK0.55745520
119MAP3K120.55486700
120NLK0.55317899
121PLK40.55247174
122BLK0.54171967
123TAOK30.52959477
124MATK0.49968280
125PTK60.49827885
126CHEK20.48403775
127PRKCE0.47123766
128MAPK30.45849328
129CDK70.45592582
130MAP3K80.43265577
131NTRK30.41534595
132EIF2AK10.41448249
133PRKCQ0.40620230
134PRKCD0.38782239
135CDK190.38593582
136AKT10.36299638
137MAPKAPK20.35593138
138ATM0.34117552
139HCK0.33110980
140STK240.32302180
141LCK0.31724361
142ARAF0.31432913
143PLK20.31421530
144CDK40.30640688
145TYRO30.28121916
146PRKCH0.27892213
147MAP3K130.27330990
148MAPKAPK30.25886373
149STK100.24151966
150FGFR30.24121758
151KSR10.23335823

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.21116732
2Phototransduction_Homo sapiens_hsa047442.70193891
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.60934534
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.53636837
5Allograft rejection_Homo sapiens_hsa053302.38542020
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.34575747
7Leishmaniasis_Homo sapiens_hsa051402.30536940
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.27341754
9Hematopoietic cell lineage_Homo sapiens_hsa046402.20866244
10NOD-like receptor signaling pathway_Homo sapiens_hsa046212.19291623
11Nitrogen metabolism_Homo sapiens_hsa009102.07769492
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.06486917
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.06455444
14Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008602.04288124
15African trypanosomiasis_Homo sapiens_hsa051432.03174996
16Systemic lupus erythematosus_Homo sapiens_hsa053222.02858981
17Type I diabetes mellitus_Homo sapiens_hsa049402.02403673
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.02282617
19Intestinal immune network for IgA production_Homo sapiens_hsa046722.00641347
20Measles_Homo sapiens_hsa051621.97299224
21Rheumatoid arthritis_Homo sapiens_hsa053231.95250339
22Malaria_Homo sapiens_hsa051441.87176740
23Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.84849695
24Fanconi anemia pathway_Homo sapiens_hsa034601.81778255
25Legionellosis_Homo sapiens_hsa051341.75436039
26Herpes simplex infection_Homo sapiens_hsa051681.70714096
27RNA polymerase_Homo sapiens_hsa030201.67831573
28DNA replication_Homo sapiens_hsa030301.63626712
29Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.63122254
30Influenza A_Homo sapiens_hsa051641.59183258
31Autoimmune thyroid disease_Homo sapiens_hsa053201.57625831
32Adipocytokine signaling pathway_Homo sapiens_hsa049201.50390943
33Selenocompound metabolism_Homo sapiens_hsa004501.49871111
34Asthma_Homo sapiens_hsa053101.49275099
35Osteoclast differentiation_Homo sapiens_hsa043801.46331235
36Staphylococcus aureus infection_Homo sapiens_hsa051501.45787555
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.45129336
38Tuberculosis_Homo sapiens_hsa051521.44545614
39TNF signaling pathway_Homo sapiens_hsa046681.43789460
40Mineral absorption_Homo sapiens_hsa049781.43589945
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.41823072
42Proteasome_Homo sapiens_hsa030501.36003524
43Primary immunodeficiency_Homo sapiens_hsa053401.33514707
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.33299104
45Pertussis_Homo sapiens_hsa051331.32745793
46Homologous recombination_Homo sapiens_hsa034401.29758224
47Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.29721276
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27008512
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.23653906
50Glycerophospholipid metabolism_Homo sapiens_hsa005641.20623304
51Mismatch repair_Homo sapiens_hsa034301.17545390
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.14693626
53Oxidative phosphorylation_Homo sapiens_hsa001901.13247709
54Nicotine addiction_Homo sapiens_hsa050331.12877222
55Jak-STAT signaling pathway_Homo sapiens_hsa046301.11153312
56Salmonella infection_Homo sapiens_hsa051321.07205306
57Butanoate metabolism_Homo sapiens_hsa006501.04181259
58Phagosome_Homo sapiens_hsa041451.00007266
59Pyrimidine metabolism_Homo sapiens_hsa002400.94146143
60Purine metabolism_Homo sapiens_hsa002300.94068285
61Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93205446
62Prion diseases_Homo sapiens_hsa050200.92482775
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91547760
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90596892
65Chemokine signaling pathway_Homo sapiens_hsa040620.90582859
66Toxoplasmosis_Homo sapiens_hsa051450.89708335
67One carbon pool by folate_Homo sapiens_hsa006700.89399947
68Basal transcription factors_Homo sapiens_hsa030220.88279545
69Alcoholism_Homo sapiens_hsa050340.85993823
70Hepatitis B_Homo sapiens_hsa051610.84622418
71Circadian entrainment_Homo sapiens_hsa047130.83070877
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81279449
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80889097
74Linoleic acid metabolism_Homo sapiens_hsa005910.80633999
75Vitamin digestion and absorption_Homo sapiens_hsa049770.80087956
76Collecting duct acid secretion_Homo sapiens_hsa049660.79473110
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79036886
78Sphingolipid metabolism_Homo sapiens_hsa006000.76552995
79Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76411135
80Apoptosis_Homo sapiens_hsa042100.75964075
81Insulin resistance_Homo sapiens_hsa049310.75222051
82ABC transporters_Homo sapiens_hsa020100.68339211
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67240793
84Hepatitis C_Homo sapiens_hsa051600.67182035
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.67130058
86Non-homologous end-joining_Homo sapiens_hsa034500.64971512
87Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64617122
88Taste transduction_Homo sapiens_hsa047420.64426868
89Regulation of autophagy_Homo sapiens_hsa041400.62212241
90Ovarian steroidogenesis_Homo sapiens_hsa049130.61716581
91Morphine addiction_Homo sapiens_hsa050320.61714350
92Arachidonic acid metabolism_Homo sapiens_hsa005900.59630491
93T cell receptor signaling pathway_Homo sapiens_hsa046600.59485592
94Other glycan degradation_Homo sapiens_hsa005110.58682127
95Inositol phosphate metabolism_Homo sapiens_hsa005620.56818748
96Parkinsons disease_Homo sapiens_hsa050120.55922674
97Fatty acid biosynthesis_Homo sapiens_hsa000610.55868190
98Antigen processing and presentation_Homo sapiens_hsa046120.52154115
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52151806
100Epstein-Barr virus infection_Homo sapiens_hsa051690.51289567
101Circadian rhythm_Homo sapiens_hsa047100.49961792
102Notch signaling pathway_Homo sapiens_hsa043300.49371243
103Huntingtons disease_Homo sapiens_hsa050160.49274560
104Serotonergic synapse_Homo sapiens_hsa047260.48285490
105Nucleotide excision repair_Homo sapiens_hsa034200.46702651
106Viral carcinogenesis_Homo sapiens_hsa052030.45484483
107Dorso-ventral axis formation_Homo sapiens_hsa043200.45472963
108AMPK signaling pathway_Homo sapiens_hsa041520.44934514
109Non-small cell lung cancer_Homo sapiens_hsa052230.44532528
110p53 signaling pathway_Homo sapiens_hsa041150.44253368
111Shigellosis_Homo sapiens_hsa051310.41722321
112B cell receptor signaling pathway_Homo sapiens_hsa046620.41444847
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41326869
114Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41227282
115Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40317432
116Melanoma_Homo sapiens_hsa052180.37750992
117Prolactin signaling pathway_Homo sapiens_hsa049170.37624060
118Calcium signaling pathway_Homo sapiens_hsa040200.37255278
119Sulfur metabolism_Homo sapiens_hsa009200.35457433
120Prostate cancer_Homo sapiens_hsa052150.35360030
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34166559
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32775086
123HTLV-I infection_Homo sapiens_hsa051660.31864110
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.31385284
125Base excision repair_Homo sapiens_hsa034100.31342047
126Type II diabetes mellitus_Homo sapiens_hsa049300.31330391
127Pancreatic secretion_Homo sapiens_hsa049720.30225415
128Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.30037679
129Cell cycle_Homo sapiens_hsa041100.29584058
130Small cell lung cancer_Homo sapiens_hsa052220.29387778
131Vitamin B6 metabolism_Homo sapiens_hsa007500.29071575
132FoxO signaling pathway_Homo sapiens_hsa040680.28836186
133Lysosome_Homo sapiens_hsa041420.27841247
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.26754026
135AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.26115807
136Alzheimers disease_Homo sapiens_hsa050100.24976141
137Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.23869986
138Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23593554
139Ether lipid metabolism_Homo sapiens_hsa005650.23455402
140Acute myeloid leukemia_Homo sapiens_hsa052210.23263616
141Olfactory transduction_Homo sapiens_hsa047400.22797702
142Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.22457447
143Pancreatic cancer_Homo sapiens_hsa052120.22203421

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