BTBD17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.14559730
2negative regulation of astrocyte differentiation (GO:0048712)5.96254639
3alanine transport (GO:0032328)5.60272137
4cellular response to cholesterol (GO:0071397)5.13520242
5glial cell proliferation (GO:0014009)5.05598271
6neuroblast proliferation (GO:0007405)5.01362878
7atrial cardiac muscle cell action potential (GO:0086014)4.85963286
8lung epithelium development (GO:0060428)4.82594112
9nucleobase catabolic process (GO:0046113)4.74891598
10epithelial cilium movement (GO:0003351)4.72053956
11nonmotile primary cilium assembly (GO:0035058)4.65329706
12calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)4.63217892
13L-serine transport (GO:0015825)4.61835958
14behavioral response to nicotine (GO:0035095)4.61569744
15intraciliary transport (GO:0042073)4.58722599
16dopaminergic neuron differentiation (GO:0071542)4.56128152
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.50779793
18negative regulation of glial cell differentiation (GO:0045686)4.44619620
19negative regulation of amyloid precursor protein catabolic process (GO:1902992)4.40301327
20negative regulation of oligodendrocyte differentiation (GO:0048715)4.35386956
21postsynaptic membrane organization (GO:0001941)4.32986614
22positive regulation of cellular amide metabolic process (GO:0034250)4.31445541
23cellular response to sterol (GO:0036315)4.31412425
24olfactory bulb development (GO:0021772)4.31388557
25regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.31361637
26C4-dicarboxylate transport (GO:0015740)4.30817606
27cell communication by electrical coupling (GO:0010644)4.23965067
28lens fiber cell development (GO:0070307)4.18132419
29dendritic spine morphogenesis (GO:0060997)4.14915231
30response to auditory stimulus (GO:0010996)4.09733069
31regulation of beta-amyloid formation (GO:1902003)4.09011565
32positive regulation of oligodendrocyte differentiation (GO:0048714)4.08620487
33astrocyte differentiation (GO:0048708)3.99560240
34cilium movement (GO:0003341)3.99501742
35positive regulation of mitochondrial fission (GO:0090141)3.96460119
36presynaptic membrane assembly (GO:0097105)3.94625531
37sodium ion export (GO:0071436)3.91761901
38cellular potassium ion homeostasis (GO:0030007)3.90721994
39serine transport (GO:0032329)3.90678454
40presynaptic membrane organization (GO:0097090)3.84478607
41spinal cord association neuron differentiation (GO:0021527)3.83304199
42regulation of astrocyte differentiation (GO:0048710)3.82345026
43axon ensheathment in central nervous system (GO:0032291)3.78042825
44central nervous system myelination (GO:0022010)3.78042825
45axonemal dynein complex assembly (GO:0070286)3.77722601
46cholesterol biosynthetic process (GO:0006695)3.76259067
47substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.75813620
48substrate-independent telencephalic tangential migration (GO:0021826)3.75813620
49chondroitin sulfate catabolic process (GO:0030207)3.74878004
50regulation of development, heterochronic (GO:0040034)3.71753778
51tongue development (GO:0043586)3.71634274
52layer formation in cerebral cortex (GO:0021819)3.64795424
53regulation of oligodendrocyte differentiation (GO:0048713)3.59892178
54lateral sprouting from an epithelium (GO:0060601)3.59784507
55amino acid import (GO:0043090)3.59690876
56regulation of timing of cell differentiation (GO:0048505)3.58259194
57cerebral cortex radially oriented cell migration (GO:0021799)3.55651967
58regulation of cilium movement (GO:0003352)3.54689684
59regulation of phospholipid biosynthetic process (GO:0071071)3.53845936
60neuronal stem cell maintenance (GO:0097150)3.53180574
61base-excision repair, AP site formation (GO:0006285)3.51043475
62negative regulation of smoothened signaling pathway (GO:0045879)3.50844475
63pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.48604889
64positive regulation of triglyceride biosynthetic process (GO:0010867)3.44160554
65sterol biosynthetic process (GO:0016126)3.38826550
66L-amino acid import (GO:0043092)3.37779589
67retinal ganglion cell axon guidance (GO:0031290)3.37778303
68cell proliferation in forebrain (GO:0021846)3.36594529
69regulation of amyloid precursor protein catabolic process (GO:1902991)3.35559181
70paraxial mesoderm development (GO:0048339)3.34275714
71cilium morphogenesis (GO:0060271)3.30010983
72locomotory exploration behavior (GO:0035641)3.26361020
73positive regulation of gastrulation (GO:2000543)3.23990119
74cilium assembly (GO:0042384)3.23322372
75positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.22295730
76mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.22295730
77cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.21040748
78synapse assembly (GO:0007416)3.20911213
79protein localization to cilium (GO:0061512)3.20491065
80neurotransmitter-gated ion channel clustering (GO:0072578)3.20475244
81retinal rod cell development (GO:0046548)3.20312208
82cilium organization (GO:0044782)3.19925144
83positive regulation of potassium ion transmembrane transport (GO:1901381)3.19267132
84auditory behavior (GO:0031223)3.18925504
85neuron recognition (GO:0008038)3.17589224
86neuronal action potential propagation (GO:0019227)3.15924784
87midbrain development (GO:0030901)3.15856984
88transmission of nerve impulse (GO:0019226)3.13384602
89negative regulation of gliogenesis (GO:0014014)3.11603411
90protein polyglutamylation (GO:0018095)3.11278889
91pyrimidine nucleotide catabolic process (GO:0006244)3.09625721
92neuron fate determination (GO:0048664)3.09442347
93central nervous system projection neuron axonogenesis (GO:0021952)3.08528581
94cerebral cortex neuron differentiation (GO:0021895)3.07143705
95establishment of mitochondrion localization (GO:0051654)3.06440705
96G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.05434897
97blood vessel maturation (GO:0001955)3.04721568
98forebrain neuron differentiation (GO:0021879)3.02861663
99regulation of glial cell differentiation (GO:0045685)3.02750700
100regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.02481068
101membrane repolarization (GO:0086009)3.01224572
102axoneme assembly (GO:0035082)3.01091602
103G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.01035867
104dermatan sulfate metabolic process (GO:0030205)3.00644602
105neuron cell-cell adhesion (GO:0007158)2.99605174
106nitric oxide mediated signal transduction (GO:0007263)2.99284177
107synaptic vesicle maturation (GO:0016188)2.97947383
108low-density lipoprotein particle remodeling (GO:0034374)2.97308064
109dermatan sulfate biosynthetic process (GO:0030208)2.96415606
110lung-associated mesenchyme development (GO:0060484)2.95452649
111negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.94716437
112heart trabecula morphogenesis (GO:0061384)2.93561682
113regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.91108554
114response to dietary excess (GO:0002021)2.90202090
115response to cholesterol (GO:0070723)2.89631884
116primitive streak formation (GO:0090009)2.88395659
117somite development (GO:0061053)2.88326731
118oligodendrocyte differentiation (GO:0048709)2.88037165
119cell proliferation involved in metanephros development (GO:0072203)2.87834941
120gamma-aminobutyric acid transport (GO:0015812)2.87424221
121adenine nucleotide transport (GO:0051503)2.86751069
122regulation of membrane repolarization (GO:0060306)2.84718941
123regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.83949055
124isoprenoid biosynthetic process (GO:0008299)2.83815974
125regulation of cholesterol biosynthetic process (GO:0045540)2.83789442
126smoothened signaling pathway (GO:0007224)2.83301216
127ovulation cycle (GO:0042698)2.82560463
128positive regulation of neural precursor cell proliferation (GO:2000179)2.81379280
129regulation of microtubule-based movement (GO:0060632)2.81378629
130cellular sodium ion homeostasis (GO:0006883)2.80736120
131positive regulation of synapse assembly (GO:0051965)2.80294874
132negative regulation of axon guidance (GO:1902668)2.79707876
133response to misfolded protein (GO:0051788)2.78377751
134limb development (GO:0060173)2.77912100
135appendage development (GO:0048736)2.77912100
136regulation of glycogen (starch) synthase activity (GO:2000465)2.77619828
137axonal fasciculation (GO:0007413)2.74695080
138regulation of cellular amide metabolic process (GO:0034248)2.74078745
139ephrin receptor signaling pathway (GO:0048013)2.73483774
140mechanosensory behavior (GO:0007638)2.72853857
141innervation (GO:0060384)2.72393455
142sterol catabolic process (GO:0016127)2.71541857
143cholesterol catabolic process (GO:0006707)2.71541857
144dorsal/ventral pattern formation (GO:0009953)2.71498114
145spinal cord development (GO:0021510)2.70943316
146potassium ion import (GO:0010107)2.70792269
147negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.70347560
148synaptic vesicle exocytosis (GO:0016079)2.70347445
149cilium or flagellum-dependent cell motility (GO:0001539)2.69276323
150glutamate secretion (GO:0014047)2.69229450
151axon extension involved in axon guidance (GO:0048846)2.69184396
152neuron projection extension involved in neuron projection guidance (GO:1902284)2.69184396
153positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.69061747
154L-serine metabolic process (GO:0006563)2.68951824
155membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.67280047
156central nervous system neuron development (GO:0021954)2.66605169
157establishment of planar polarity (GO:0001736)2.66048830
158motile cilium assembly (GO:0044458)2.64328626
159regulation of respiratory system process (GO:0044065)2.62223357
160sequestering of actin monomers (GO:0042989)2.58403354
161protein localization to synapse (GO:0035418)2.56996944
162synaptic vesicle endocytosis (GO:0048488)2.56391397
163cranial nerve morphogenesis (GO:0021602)2.56284473
164regulation of Rac GTPase activity (GO:0032314)2.56002638
165central nervous system neuron axonogenesis (GO:0021955)2.55780545
166negative regulation of transcription regulatory region DNA binding (GO:2000678)2.55470293
167ubiquinone metabolic process (GO:0006743)2.55377155
168regulation of mitochondrial fission (GO:0090140)2.54923392
169microtubule depolymerization (GO:0007019)2.54800745
170hippocampus development (GO:0021766)2.54771760
171ganglion development (GO:0061548)2.53754720
172synaptic transmission, cholinergic (GO:0007271)2.52828699
173adult walking behavior (GO:0007628)2.52416635
174brain morphogenesis (GO:0048854)2.51408217
175negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.51069932
176camera-type eye morphogenesis (GO:0048593)2.45350574
177neural precursor cell proliferation (GO:0061351)2.44280528
178positive regulation of neuroblast proliferation (GO:0002052)2.43892210
179radial glial cell differentiation (GO:0060019)2.43466458
180short-term memory (GO:0007614)2.43127144
181regulation of collateral sprouting (GO:0048670)2.42813128
182left/right pattern formation (GO:0060972)2.42284446

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.40291060
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.58470969
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.55108375
4SUZ12_16625203_ChIP-ChIP_MESCs_Mouse3.53451238
5EED_16625203_ChIP-ChIP_MESCs_Mouse3.50789701
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.17227195
7JARID2_20075857_ChIP-Seq_MESCs_Mouse3.11142286
8EZH2_27304074_Chip-Seq_ESCs_Mouse3.06033963
9JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00700159
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.92594427
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.92594427
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.89447874
13* RNF2_27304074_Chip-Seq_ESCs_Mouse2.88496695
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.66565779
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56278492
16IGF1R_20145208_ChIP-Seq_DFB_Human2.54455609
17PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.53588296
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.51172601
19RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.50074427
20DROSHA_22980978_ChIP-Seq_HELA_Human2.44998346
21* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.43892638
22REST_21632747_ChIP-Seq_MESCs_Mouse2.43880268
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.43377213
24* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.36784198
25* OLIG2_26023283_ChIP-Seq_AINV15_Mouse2.17295145
26IRF1_19129219_ChIP-ChIP_H3396_Human2.14826798
27IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09304021
28ERG_21242973_ChIP-ChIP_JURKAT_Human2.07927765
29TP53_20018659_ChIP-ChIP_R1E_Mouse2.04758315
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.02567175
31REST_18959480_ChIP-ChIP_MESCs_Mouse1.97736711
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.95878235
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.94887474
34EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90758460
35RNF2_27304074_Chip-Seq_NSC_Mouse1.81193849
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.80780334
37* RING1B_27294783_Chip-Seq_ESCs_Mouse1.80000856
38AR_21572438_ChIP-Seq_LNCaP_Human1.79060284
39GBX2_23144817_ChIP-Seq_PC3_Human1.77010884
40TAF15_26573619_Chip-Seq_HEK293_Human1.72265126
41PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.69658777
42TRIM28_21343339_ChIP-Seq_HEK293_Human1.69076616
43RARB_27405468_Chip-Seq_BRAIN_Mouse1.66232772
44HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.64606797
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.60223111
46SOX2_18555785_ChIP-Seq_MESCs_Mouse1.58899137
47TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.55692827
48POU5F1_16153702_ChIP-ChIP_HESCs_Human1.54152707
49RING1B_27294783_Chip-Seq_NPCs_Mouse1.51998159
50ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50262291
51EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.49546819
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.47744060
53ZFP281_18757296_ChIP-ChIP_E14_Mouse1.44375590
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.40446512
55E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39500262
56NR3C1_23031785_ChIP-Seq_PC12_Mouse1.39130837
57ZNF274_21170338_ChIP-Seq_K562_Hela1.34546464
58GABP_17652178_ChIP-ChIP_JURKAT_Human1.34505711
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.31654205
60AR_19668381_ChIP-Seq_PC3_Human1.30487364
61CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.28630843
62FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.28323423
63CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27834166
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25689085
65ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.25523615
66CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.24774887
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24162151
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23523843
69GATA1_26923725_Chip-Seq_HPCs_Mouse1.23189205
70VDR_22108803_ChIP-Seq_LS180_Human1.22151888
71RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20664478
72SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.20258842
73EWS_26573619_Chip-Seq_HEK293_Human1.20208635
74PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19639176
75SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.19266031
76* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18687547
77POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17881124
78FUS_26573619_Chip-Seq_HEK293_Human1.17829574
79CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.15806994
80GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15412271
81MYC_18940864_ChIP-ChIP_HL60_Human1.14444288
82WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13734842
83DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10274537
84SOX2_16153702_ChIP-ChIP_HESCs_Human1.09673384
85RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.09083190
86MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08828456
87SALL1_21062744_ChIP-ChIP_HESCs_Human1.08393990
88POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.07751601
89KDM2B_26808549_Chip-Seq_K562_Human1.06609558
90POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05578646
91SOX2_21211035_ChIP-Seq_LN229_Gbm1.04836132
92KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04779868
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04672526
94KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04355222
95ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04022305
96NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.03199706
97PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.02667132
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02373614
99TBX3_20139965_ChIP-Seq_MESCs_Mouse0.99986087
100SMAD3_21741376_ChIP-Seq_ESCs_Human0.98791291
101YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98352770
102TBX3_20139965_ChIP-Seq_ESCs_Mouse0.98183120
103WDR5_24793694_ChIP-Seq_LNCAP_Human0.98115604
104TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97743746
105MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97701373
106EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96585901
107SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96102042
108RUNX2_22187159_ChIP-Seq_PCA_Human0.95724741
109MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95389487
110TP63_19390658_ChIP-ChIP_HaCaT_Human0.94762619
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94529064
112YY1_21170310_ChIP-Seq_MESCs_Mouse0.94079283
113BCAT_22108803_ChIP-Seq_LS180_Human0.93959015
114SOX9_26525672_Chip-Seq_HEART_Mouse0.92599378
115ZFP281_27345836_Chip-Seq_ESCs_Mouse0.92346652
116P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91494307
117SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90593100
118EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90033992
119TOP2B_26459242_ChIP-Seq_MCF-7_Human0.88947347
120VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88331396
121GABP_19822575_ChIP-Seq_HepG2_Human0.88244985
122AR_25329375_ChIP-Seq_VCAP_Human0.88169812
123SMAD4_21799915_ChIP-Seq_A2780_Human0.88105601
124SMAD4_21741376_ChIP-Seq_HESCs_Human0.87932743
125GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87816054
126P300_19829295_ChIP-Seq_ESCs_Human0.87323122
127IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87237635
128CBP_20019798_ChIP-Seq_JUKART_Human0.87237635
129GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87006698
130AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.86251846
131* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86078550
132SMAD3_21741376_ChIP-Seq_EPCs_Human0.85406555
133POU5F1_16518401_ChIP-PET_MESCs_Mouse0.85293543
134TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85065318
135POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85065318
136BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.85025595
137SOX3_22085726_ChIP-Seq_NPCs_Mouse0.84816649
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.84650868
139ESR2_21235772_ChIP-Seq_MCF-7_Human0.84454106
140ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.83689029
141CDX2_19796622_ChIP-Seq_MESCs_Mouse0.83620962
142TP53_22573176_ChIP-Seq_HFKS_Human0.82667262
143EST1_17652178_ChIP-ChIP_JURKAT_Human0.82600524
144SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.82554180
145RXR_22108803_ChIP-Seq_LS180_Human0.82468570
146NANOG_16153702_ChIP-ChIP_HESCs_Human0.82461319
147TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.82017228
148KLF5_20875108_ChIP-Seq_MESCs_Mouse0.81617058
149TET1_21490601_ChIP-Seq_MESCs_Mouse0.81149085
150OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.80523074
151TAL1_26923725_Chip-Seq_HPCs_Mouse0.80360850
152TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.79425813

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ4.56781727
2MP0002653_abnormal_ependyma_morphology4.09266855
3MP0003122_maternal_imprinting3.49138759
4MP0000566_synostosis3.23389471
5MP0005646_abnormal_pituitary_gland2.98509377
6MP0003329_amyloid_beta_deposits2.90068333
7MP0002638_abnormal_pupillary_reflex2.73934595
8MP0004859_abnormal_synaptic_plasticity2.54800950
9MP0002254_reproductive_system_inflammat2.52479529
10MP0004858_abnormal_nervous_system2.51291145
11MP0006276_abnormal_autonomic_nervous2.46597852
12MP0010030_abnormal_orbit_morphology2.45942734
13MP0001502_abnormal_circadian_rhythm2.41897382
14MP0003787_abnormal_imprinting2.31775728
15MP0003690_abnormal_glial_cell2.18713846
16MP0009780_abnormal_chondrocyte_physiolo2.14989979
17MP0003121_genomic_imprinting2.14262741
18MP0002909_abnormal_adrenal_gland2.10953018
19MP0001486_abnormal_startle_reflex2.07708718
20MP0006292_abnormal_olfactory_placode2.06519900
21MP0000778_abnormal_nervous_system2.04569749
22MP0003635_abnormal_synaptic_transmissio1.95054241
23MP0005379_endocrine/exocrine_gland_phen1.94476574
24MP0009840_abnormal_foam_cell1.86969771
25MP0005645_abnormal_hypothalamus_physiol1.86055515
26MP0002234_abnormal_pharynx_morphology1.85156065
27MP0000462_abnormal_digestive_system1.77935396
28MP0000049_abnormal_middle_ear1.75951658
29MP0005248_abnormal_Harderian_gland1.75796884
30MP0003634_abnormal_glial_cell1.73924326
31MP0002064_seizures1.65142367
32MP0001984_abnormal_olfaction1.64172277
33MP0006072_abnormal_retinal_apoptosis1.60940573
34MP0002063_abnormal_learning/memory/cond1.60024405
35MP0003183_abnormal_peptide_metabolism1.59982469
36MP0002822_catalepsy1.56413192
37MP0005253_abnormal_eye_physiology1.54715622
38MP0002557_abnormal_social/conspecific_i1.54445735
39MP0004270_analgesia1.53973932
40MP0002090_abnormal_vision1.53521537
41MP0004885_abnormal_endolymph1.51331352
42MP0002938_white_spotting1.51097161
43MP0000955_abnormal_spinal_cord1.48879977
44MP0002572_abnormal_emotion/affect_behav1.48168211
45MP0004133_heterotaxia1.47960921
46MP0000631_abnormal_neuroendocrine_gland1.47042847
47MP0005551_abnormal_eye_electrophysiolog1.44938813
48MP0003137_abnormal_impulse_conducting1.44651187
49MP0009046_muscle_twitch1.39993738
50MP0000026_abnormal_inner_ear1.35860235
51MP0004142_abnormal_muscle_tone1.33521846
52MP0009384_cardiac_valve_regurgitation1.32650194
53MP0008569_lethality_at_weaning1.29597903
54MP0009745_abnormal_behavioral_response1.28220106
55MP0003632_abnormal_nervous_system1.27503815
56MP0000604_amyloidosis1.25701229
57MP0009053_abnormal_anal_canal1.24435538
58MP0002882_abnormal_neuron_morphology1.24230974
59MP0002152_abnormal_brain_morphology1.23963079
60MP0001529_abnormal_vocalization1.23067225
61MP0000428_abnormal_craniofacial_morphol1.21783327
62MP0002733_abnormal_thermal_nociception1.19743803
63MP0000579_abnormal_nail_morphology1.19501753
64MP0002163_abnormal_gland_morphology1.18311269
65MP0005423_abnormal_somatic_nervous1.17158982
66MP0003115_abnormal_respiratory_system1.16910301
67MP0002067_abnormal_sensory_capabilities1.16643166
68MP0003942_abnormal_urinary_system1.14049413
69MP0002184_abnormal_innervation1.13392496
70MP0001485_abnormal_pinna_reflex1.11283303
71MP0003279_aneurysm1.10970086
72MP0002734_abnormal_mechanical_nocicepti1.09458813
73MP0008789_abnormal_olfactory_epithelium1.07867328
74MP0002249_abnormal_larynx_morphology1.06816323
75MP0003938_abnormal_ear_development1.06613291
76MP0001963_abnormal_hearing_physiology1.06346258
77MP0003123_paternal_imprinting1.05996835
78MP0008961_abnormal_basal_metabolism1.04051881
79MP0005499_abnormal_olfactory_system1.04027503
80MP0005394_taste/olfaction_phenotype1.04027503
81MP0004811_abnormal_neuron_physiology1.03508841
82MP0001299_abnormal_eye_distance/1.03241105
83MP0008877_abnormal_DNA_methylation1.01158535
84MP0002127_abnormal_cardiovascular_syste1.00534683
85MP0006054_spinal_hemorrhage1.00253684
86MP0003861_abnormal_nervous_system0.99818299
87MP0005171_absent_coat_pigmentation0.99599427
88MP0002697_abnormal_eye_size0.98691144
89MP0002751_abnormal_autonomic_nervous0.98526068
90MP0003755_abnormal_palate_morphology0.98067799
91MP0003890_abnormal_embryonic-extraembry0.98002491
92MP0000647_abnormal_sebaceous_gland0.97840758
93MP0005391_vision/eye_phenotype0.97802610
94MP0002752_abnormal_somatic_nervous0.97165866
95MP0002102_abnormal_ear_morphology0.97023972
96MP0002272_abnormal_nervous_system0.96675382
97MP0001440_abnormal_grooming_behavior0.96126581
98MP0002932_abnormal_joint_morphology0.94886759
99MP0001270_distended_abdomen0.93173559
100MP0001968_abnormal_touch/_nociception0.92062872
101MP0001286_abnormal_eye_development0.89964501
102MP0002092_abnormal_eye_morphology0.89605628
103MP0002736_abnormal_nociception_after0.89123398
104MP0002066_abnormal_motor_capabilities/c0.88368572
105MP0005377_hearing/vestibular/ear_phenot0.88330327
106MP0003878_abnormal_ear_physiology0.88330327
107MP0002069_abnormal_eating/drinking_beha0.88248150
108MP0003119_abnormal_digestive_system0.88115407
109MP0003011_delayed_dark_adaptation0.88039021
110MP0003880_abnormal_central_pattern0.87455919
111MP0001905_abnormal_dopamine_level0.86760688
112MP0000372_irregular_coat_pigmentation0.86079369
113MP0002116_abnormal_craniofacial_bone0.85703252
114MP0003937_abnormal_limbs/digits/tail_de0.85691497
115MP0005195_abnormal_posterior_eye0.85656402
116MP0003136_yellow_coat_color0.84749641
117MP0001970_abnormal_pain_threshold0.83207649
118MP0003075_altered_response_to0.82698343
119MP0002233_abnormal_nose_morphology0.82510532
120MP0004742_abnormal_vestibular_system0.81484092
121MP0004924_abnormal_behavior0.80677437
122MP0005386_behavior/neurological_phenoty0.80677437
123MP0001293_anophthalmia0.80371428
124MP0003631_nervous_system_phenotype0.80337128
125MP0002282_abnormal_trachea_morphology0.77682126
126MP0002928_abnormal_bile_duct0.77531544
127MP0000534_abnormal_ureter_morphology0.76604314
128MP0004147_increased_porphyrin_level0.73195527
129MP0001324_abnormal_eye_pigmentation0.69825468

Predicted human phenotypes

RankGene SetZ-score
1Megalencephaly (HP:0001355)7.93568498
2Neurofibrillary tangles (HP:0002185)4.98913696
3Aplasia involving bones of the extremities (HP:0009825)4.84792844
4Aplasia involving bones of the upper limbs (HP:0009823)4.84792844
5Aplasia of the phalanges of the hand (HP:0009802)4.84792844
6Maternal diabetes (HP:0009800)4.39186601
7True hermaphroditism (HP:0010459)4.10038153
8Gait imbalance (HP:0002141)4.03400184
9Back pain (HP:0003418)3.99145363
10Medial flaring of the eyebrow (HP:0010747)3.97966101
11Short middle phalanx of the 5th finger (HP:0004220)3.94778775
12Pancreatic fibrosis (HP:0100732)3.93973198
13Congenital primary aphakia (HP:0007707)3.92231846
14Split foot (HP:0001839)3.82637090
15Concave nail (HP:0001598)3.74620041
16Cerebral inclusion bodies (HP:0100314)3.71026917
17Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.65347250
18Nephrogenic diabetes insipidus (HP:0009806)3.58289568
19Abnormality of midbrain morphology (HP:0002418)3.47192765
20Molar tooth sign on MRI (HP:0002419)3.47192765
21Clumsiness (HP:0002312)3.43573595
22Pseudobulbar signs (HP:0002200)3.42905622
23Pancreatic cysts (HP:0001737)3.39497008
24Polyphagia (HP:0002591)3.36779148
25Septo-optic dysplasia (HP:0100842)3.31154024
26Nephronophthisis (HP:0000090)3.22510728
27Hemiparesis (HP:0001269)3.19553701
28Hyperglycinemia (HP:0002154)3.17479998
29Abnormal respiratory motile cilium physiology (HP:0012261)3.15343184
30Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)3.06294264
31Postaxial foot polydactyly (HP:0001830)3.04862131
32Abnormal respiratory motile cilium morphology (HP:0005938)2.99122044
33Abnormal respiratory epithelium morphology (HP:0012253)2.99122044
34Occipital encephalocele (HP:0002085)2.94495036
35Vaginal atresia (HP:0000148)2.94356580
36Genital tract atresia (HP:0001827)2.89429140
37Ketoacidosis (HP:0001993)2.86058592
38Supernumerary spleens (HP:0009799)2.85406190
39Abnormality of binocular vision (HP:0011514)2.85355657
40Diplopia (HP:0000651)2.85355657
41Aplasia/Hypoplasia of the tongue (HP:0010295)2.84829557
42Postaxial hand polydactyly (HP:0001162)2.84474849
43Sclerocornea (HP:0000647)2.83513980
44Anophthalmia (HP:0000528)2.81935901
45Broad foot (HP:0001769)2.81246314
46Poor coordination (HP:0002370)2.80699114
47Abnormal ciliary motility (HP:0012262)2.77031454
48Cystic liver disease (HP:0006706)2.73309963
49Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.72093108
50Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.71335373
51Mixed hearing impairment (HP:0000410)2.71235778
52Oligodactyly (hands) (HP:0001180)2.70341385
53Specific learning disability (HP:0001328)2.69837747
54Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.67988099
55Anencephaly (HP:0002323)2.64565814
56Hepatoblastoma (HP:0002884)2.61746630
57Retinal dysplasia (HP:0007973)2.61586788
58Hypoglycemic seizures (HP:0002173)2.54628034
59Chronic hepatic failure (HP:0100626)2.53921612
60High anterior hairline (HP:0009890)2.53356675
61Narrow nasal bridge (HP:0000446)2.52261485
62Late onset (HP:0003584)2.50786391
63Rhinitis (HP:0012384)2.49501725
64Abnormality of the labia minora (HP:0012880)2.48638370
65Adrenal hypoplasia (HP:0000835)2.48460616
66Humeroradial synostosis (HP:0003041)2.47302579
67Synostosis involving the elbow (HP:0003938)2.47302579
68Progressive neurologic deterioration (HP:0002344)2.47085844
69Preaxial hand polydactyly (HP:0001177)2.46791574
70Hemiplegia (HP:0002301)2.46310270
71Abnormality of the parathyroid morphology (HP:0011766)2.46013238
72Abnormality of the renal medulla (HP:0100957)2.45447993
73Abnormality of the axillary hair (HP:0100134)2.42490041
74Abnormality of secondary sexual hair (HP:0009888)2.42490041
75Abnormality of the phalanges of the 5th finger (HP:0004213)2.41408977
76Hypoplastic pelvis (HP:0008839)2.38280623
77Large for gestational age (HP:0001520)2.37216245
78Decreased testicular size (HP:0008734)2.37083484
79Labial hypoplasia (HP:0000066)2.37044315
80Renal dysplasia (HP:0000110)2.33991535
81Aplasia of the musculature (HP:0100854)2.33391249
82Bifid tongue (HP:0010297)2.31832714
83Short 5th finger (HP:0009237)2.27049127
84Hyperinsulinemic hypoglycemia (HP:0000825)2.26770740
85Colon cancer (HP:0003003)2.25602793
86Abnormal eating behavior (HP:0100738)2.23721008
87Exercise-induced muscle cramps (HP:0003710)2.23659985
88Congenital hepatic fibrosis (HP:0002612)2.23552458
89Pterygium (HP:0001059)2.23042766
90Prenatal maternal abnormality (HP:0002686)2.22437296
91Adactyly (HP:0009776)2.22263089
92Cortical dysplasia (HP:0002539)2.21902007
93Cubitus valgus (HP:0002967)2.21502350
94Vitreoretinal degeneration (HP:0000655)2.19820801
95Abnormal biliary tract physiology (HP:0012439)2.19643335
96Bile duct proliferation (HP:0001408)2.19643335
97Abnormal number of incisors (HP:0011064)2.18964849
98Supranuclear gaze palsy (HP:0000605)2.17268571
99Type II lissencephaly (HP:0007260)2.16057155
100Bronchomalacia (HP:0002780)2.14298739
101Abnormality of serine family amino acid metabolism (HP:0010894)2.14159984
102Abnormality of glycine metabolism (HP:0010895)2.14159984
103Aplasia/Hypoplasia of the spleen (HP:0010451)2.11499892
104Hypoplastic female external genitalia (HP:0012815)2.11197596
105Holoprosencephaly (HP:0001360)2.09788943
106Optic nerve coloboma (HP:0000588)2.08698673
107Optic nerve hypoplasia (HP:0000609)2.07538154
108Growth hormone deficiency (HP:0000824)2.07287616
109Renal duplication (HP:0000075)2.06986546
110Oligodactyly (HP:0012165)2.06737477
111Aganglionic megacolon (HP:0002251)2.04710550
112Narrow forehead (HP:0000341)2.01748541
113Abnormality of chromosome segregation (HP:0002916)2.01746488
114Broad alveolar ridges (HP:0000187)2.00825216
115Absent septum pellucidum (HP:0001331)1.99988605
116Bilateral microphthalmos (HP:0007633)1.99498511
117Hemivertebrae (HP:0002937)1.99439256
118Asplenia (HP:0001746)1.98830522
119Epileptic encephalopathy (HP:0200134)1.97706737
120Abnormality of the aortic arch (HP:0012303)1.97394667
121Hypsarrhythmia (HP:0002521)1.95931693
122Micropenis (HP:0000054)1.95735810
123Dandy-Walker malformation (HP:0001305)1.95671315
124Anosmia (HP:0000458)1.95570984
125Aplasia/Hypoplasia of the lens (HP:0008063)1.94698725
126Lissencephaly (HP:0001339)1.93959734
127Short tibia (HP:0005736)1.93715373
128Intestinal atresia (HP:0011100)1.92830143
129Absent hair (HP:0002298)1.90589239
130EEG with generalized epileptiform discharges (HP:0011198)1.90352389
131Chronic bronchitis (HP:0004469)1.89626317
132Selective tooth agenesis (HP:0001592)1.89131313
133Abnormality of the 4th metacarpal (HP:0010012)1.88836979
134Insomnia (HP:0100785)1.87963545
135Short 4th metacarpal (HP:0010044)1.86467734
136Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.86467734
137Long nose (HP:0003189)1.86397242
138Abnormality of abdominal situs (HP:0011620)1.86011457
139Abdominal situs inversus (HP:0003363)1.86011457
140Fibular aplasia (HP:0002990)1.85878035
141Renal hypoplasia (HP:0000089)1.85781667
142Tubulointerstitial nephritis (HP:0001970)1.85521342
143Abnormality of the metopic suture (HP:0005556)1.85265995
144Hypoplastic left heart (HP:0004383)1.85127820
145Fibular hypoplasia (HP:0003038)1.85022876
146Aplasia/Hypoplasia of the tibia (HP:0005772)1.83924381
147Keratoconus (HP:0000563)1.83598658
148Increased corneal curvature (HP:0100692)1.83598658
149Drooling (HP:0002307)1.83592104
150Symptomatic seizures (HP:0011145)1.83181663
151Scotoma (HP:0000575)1.82842716
152Median cleft lip (HP:0000161)1.82402014
153Dynein arm defect of respiratory motile cilia (HP:0012255)1.82101657
154Absent/shortened dynein arms (HP:0200106)1.82101657
155Nuclear cataract (HP:0100018)1.81698781
156Ankyloglossia (HP:0010296)1.81529179
157Prominent nasal bridge (HP:0000426)1.81109141
158Abnormality of the intervertebral disk (HP:0005108)1.80666118
159Pachygyria (HP:0001302)1.80531529
160Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.80448891
161Epileptiform EEG discharges (HP:0011182)1.80233756
162Multicystic kidney dysplasia (HP:0000003)1.79700612
163Thyroid-stimulating hormone excess (HP:0002925)1.78229795
164Cutaneous syndactyly (HP:0012725)1.77638679
165Athetosis (HP:0002305)1.76931337
166Increased number of teeth (HP:0011069)1.73979045
167Absent toe (HP:0010760)1.73741065
168Exostoses (HP:0100777)1.71487287
169Abnormality of the dental pulp (HP:0006479)1.70551971
170Anomalous pulmonary venous return (HP:0010772)1.70211448
171Abnormality of calcium-phosphate metabolism (HP:0100530)1.67296881
172Myokymia (HP:0002411)1.66866075
173Preaxial foot polydactyly (HP:0001841)1.66495202
174Short hallux (HP:0010109)1.65577126
175Rib fusion (HP:0000902)1.65052161
176Hyperglycinuria (HP:0003108)1.64852550
177Abnormality of the middle phalanges of the toes (HP:0010183)1.64320081
178Depression (HP:0000716)1.63350527
179Hypoplastic labia majora (HP:0000059)1.58885909
180Turricephaly (HP:0000262)1.57509962
181Ketosis (HP:0001946)1.56569744
182Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.56063565
183Abnormality of the septum pellucidum (HP:0007375)1.54927676
184Mesangial abnormality (HP:0001966)1.53065993
185Aplasia/Hypoplasia of the hallux (HP:0008362)1.53006942

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA46.42277343
2LMTK25.83066382
3NTRK23.88668163
4PHKG23.33636911
5PHKG13.33636911
6SIK13.15282087
7PRKD33.08665407
8MAP2K72.57956173
9CASK2.51674110
10SIK32.48610294
11TNIK2.36506111
12TRIM282.28329950
13KSR12.26049536
14MAP4K22.22640486
15SRPK12.22227248
16INSRR2.16347139
17TRIB32.04626260
18PASK2.04290676
19EPHB21.92384856
20CSNK1G31.81168826
21UHMK11.71433743
22CSNK1A1L1.70741924
23CSNK1G21.70117775
24MINK11.62048912
25BCKDK1.52189162
26EPHA31.50579003
27CSNK1G11.46093767
28ERBB31.41636487
29TYRO31.40328840
30NTRK31.37540353
31PLK21.34087973
32MKNK11.29813129
33SGK4941.27550642
34SGK2231.27550642
35RPS6KA41.24918232
36NTRK11.21821965
37ICK1.21279550
38MAPK131.20953223
39CDC71.18326925
40MUSK1.17703749
41GRK11.17097217
42ERN11.16264823
43ADRBK21.15982627
44MARK11.11404393
45BCR1.07121848
46FGFR21.03784097
47PBK1.02495032
48PAK61.00015033
49PAK30.99003318
50BRSK10.98794980
51TESK20.98437134
52CAMK1G0.98188152
53DYRK30.94936886
54CDC42BPA0.93034933
55EIF2AK10.91892283
56SGK20.91081976
57ERBB20.89810043
58MAP2K40.88129579
59IRAK20.87969052
60BMPR1B0.86778287
61LIMK10.85937260
62CDK180.83605232
63CDK50.82767771
64STK160.82723876
65PKN10.82296094
66DYRK1A0.82100036
67PRKCG0.81632027
68EPHB10.81616982
69ZAK0.80513573
70TIE10.78961512
71CAMK1D0.78316042
72MKNK20.77451401
73DMPK0.76549199
74PRPF4B0.76056262
75NEK10.76034779
76MAP3K110.75359823
77NEK60.75194824
78CDK150.75056037
79PDGFRA0.73588152
80MELK0.72863623
81PLK10.71997909
82DYRK20.69721429
83CDK11A0.67424546
84NUAK10.66721821
85CDK140.65521670
86SGK30.61701844
87MAPK150.61524053
88PRKD20.60209482
89WNK40.60150185
90CDK190.60069533
91DDR20.58667348
92HIPK20.58109910
93PLK30.57749188
94PRKCE0.57386297
95ROCK20.56947991
96AURKA0.56255960
97CAMKK10.55242767
98CSNK1A10.52572452
99ADRBK10.51793182
100CAMK40.51649918
101BRD40.51453952
102ERBB40.51402673
103CDK80.51223898
104TAOK20.50848818
105PLK40.49886809
106PRKCH0.48723435
107DYRK1B0.47537610
108FGFR10.47308539
109ROCK10.47268045
110NEK20.47143953
111FGR0.46880751
112MAPK120.44843663
113MAP3K90.44658972
114MATK0.44330364
115CCNB10.44241992
116ATR0.40410002
117PINK10.40202292
118SIK20.39798810
119CAMKK20.38326965
120CHEK20.38269009
121STK38L0.36819073
122WEE10.36730094
123MAPK70.35454607
124SRC0.35134081
125KSR20.34540622
126RPS6KA30.34431353
127SGK10.33765929
128CAMK2B0.33132116
129MAP3K40.33103159
130WNK30.33044879
131AURKB0.31996933
132AKT20.31836326
133MARK20.30882134
134CAMK2A0.30724662
135PRKCA0.30560510
136PRKACG0.30517996
137PRKACA0.28634543
138CAMK2D0.28396726
139PDK40.28375937
140PDK30.28375937
141FER0.28279916
142VRK10.27977962
143MAPK100.27514911
144STK390.27230442
145CSNK1D0.26946562
146CAMK10.25338372
147MAPK110.24583324
148AKT10.23755120
149PRKCZ0.23378633
150LRRK20.22871827
151MAPK90.21724574

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.56674880
2Nitrogen metabolism_Homo sapiens_hsa009104.24598933
3Fatty acid metabolism_Homo sapiens_hsa012123.02685094
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.78802058
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.62582241
6Fatty acid degradation_Homo sapiens_hsa000712.37537339
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.31109445
8Insulin secretion_Homo sapiens_hsa049112.25798178
9Basal cell carcinoma_Homo sapiens_hsa052172.21473371
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.16001534
11Nicotine addiction_Homo sapiens_hsa050332.02515724
12GABAergic synapse_Homo sapiens_hsa047271.97724483
13Protein export_Homo sapiens_hsa030601.93989561
14Cocaine addiction_Homo sapiens_hsa050301.89288817
15Parkinsons disease_Homo sapiens_hsa050121.79562396
16Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.79022749
17Oxidative phosphorylation_Homo sapiens_hsa001901.74982211
18Hedgehog signaling pathway_Homo sapiens_hsa043401.73713155
19Glutamatergic synapse_Homo sapiens_hsa047241.68584813
20Circadian rhythm_Homo sapiens_hsa047101.66134325
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.62215225
22Circadian entrainment_Homo sapiens_hsa047131.52255675
23Caffeine metabolism_Homo sapiens_hsa002321.46272738
24Notch signaling pathway_Homo sapiens_hsa043301.42201937
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.41872708
26Phototransduction_Homo sapiens_hsa047441.41332797
27Sulfur metabolism_Homo sapiens_hsa009201.39492257
28Steroid biosynthesis_Homo sapiens_hsa001001.39113408
29Huntingtons disease_Homo sapiens_hsa050161.34200060
30N-Glycan biosynthesis_Homo sapiens_hsa005101.30960344
31Salivary secretion_Homo sapiens_hsa049701.29158459
32Melanogenesis_Homo sapiens_hsa049161.28892749
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25599502
34Morphine addiction_Homo sapiens_hsa050321.24343525
35Cardiac muscle contraction_Homo sapiens_hsa042601.23549173
36RNA polymerase_Homo sapiens_hsa030201.21338257
37Non-homologous end-joining_Homo sapiens_hsa034501.20563921
38Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.20259075
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.19347032
40Fanconi anemia pathway_Homo sapiens_hsa034601.18950049
41Ribosome_Homo sapiens_hsa030101.16721100
42Carbohydrate digestion and absorption_Homo sapiens_hsa049731.16718840
43Synaptic vesicle cycle_Homo sapiens_hsa047211.16176339
44Base excision repair_Homo sapiens_hsa034101.13483762
45Gastric acid secretion_Homo sapiens_hsa049711.11262599
46Fatty acid elongation_Homo sapiens_hsa000621.11166549
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09991204
48Linoleic acid metabolism_Homo sapiens_hsa005911.03845526
49PPAR signaling pathway_Homo sapiens_hsa033201.03541289
50Amphetamine addiction_Homo sapiens_hsa050311.01437653
51Axon guidance_Homo sapiens_hsa043600.99806160
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98003061
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97972245
54Butanoate metabolism_Homo sapiens_hsa006500.97510093
55Alzheimers disease_Homo sapiens_hsa050100.94760727
56Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.93464155
57Long-term potentiation_Homo sapiens_hsa047200.91412640
58Primary bile acid biosynthesis_Homo sapiens_hsa001200.91166057
59Propanoate metabolism_Homo sapiens_hsa006400.89898621
60Biosynthesis of amino acids_Homo sapiens_hsa012300.89096464
61Regulation of autophagy_Homo sapiens_hsa041400.88558406
62Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88354632
63Basal transcription factors_Homo sapiens_hsa030220.88066644
64Gap junction_Homo sapiens_hsa045400.87712984
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.85950108
66Olfactory transduction_Homo sapiens_hsa047400.85612238
67Wnt signaling pathway_Homo sapiens_hsa043100.85573919
68RNA degradation_Homo sapiens_hsa030180.82627084
69Cholinergic synapse_Homo sapiens_hsa047250.82502324
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82149272
71Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.82090658
72Dopaminergic synapse_Homo sapiens_hsa047280.80663956
73Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.80556327
74Glucagon signaling pathway_Homo sapiens_hsa049220.80157273
75Hippo signaling pathway_Homo sapiens_hsa043900.78543729
76Arginine and proline metabolism_Homo sapiens_hsa003300.77394656
77Type I diabetes mellitus_Homo sapiens_hsa049400.77204600
78Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76150860
79Serotonergic synapse_Homo sapiens_hsa047260.75848575
80beta-Alanine metabolism_Homo sapiens_hsa004100.75647404
81Pyruvate metabolism_Homo sapiens_hsa006200.75333740
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74624995
83Vitamin B6 metabolism_Homo sapiens_hsa007500.74546202
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74250279
85Metabolic pathways_Homo sapiens_hsa011000.73580434
86Thyroid hormone synthesis_Homo sapiens_hsa049180.73245001
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72226670
88cAMP signaling pathway_Homo sapiens_hsa040240.71160093
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71134001
90Lysosome_Homo sapiens_hsa041420.70957554
91Spliceosome_Homo sapiens_hsa030400.70736487
92Taste transduction_Homo sapiens_hsa047420.70462976
93Fructose and mannose metabolism_Homo sapiens_hsa000510.69888876
94Alcoholism_Homo sapiens_hsa050340.68558743
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67924756
96Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66773002
97Tryptophan metabolism_Homo sapiens_hsa003800.66761244
98Pentose phosphate pathway_Homo sapiens_hsa000300.64701644
99Bile secretion_Homo sapiens_hsa049760.64413010
100Pancreatic secretion_Homo sapiens_hsa049720.64311402
101Calcium signaling pathway_Homo sapiens_hsa040200.64065286
102Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.63369262
103Vibrio cholerae infection_Homo sapiens_hsa051100.62884376
104Sphingolipid metabolism_Homo sapiens_hsa006000.62880612
105Glycosaminoglycan degradation_Homo sapiens_hsa005310.61411666
106Peroxisome_Homo sapiens_hsa041460.61202787
107Type II diabetes mellitus_Homo sapiens_hsa049300.61027919
108Prion diseases_Homo sapiens_hsa050200.60080302
109Folate biosynthesis_Homo sapiens_hsa007900.59021219
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.58272515
111Mineral absorption_Homo sapiens_hsa049780.57229703
112Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55411970
113Carbon metabolism_Homo sapiens_hsa012000.54951003
114Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54648428
115Dorso-ventral axis formation_Homo sapiens_hsa043200.54282054
116Pyrimidine metabolism_Homo sapiens_hsa002400.54267857
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.53976561
118Sulfur relay system_Homo sapiens_hsa041220.53574574
119Galactose metabolism_Homo sapiens_hsa000520.53095948
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52866981
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51651074
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49929356
123Estrogen signaling pathway_Homo sapiens_hsa049150.49339416
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.49225856
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.48774841
1262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.48278246
127Ether lipid metabolism_Homo sapiens_hsa005650.45971873
128Renin secretion_Homo sapiens_hsa049240.45892013
129Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.44994694
130Lysine degradation_Homo sapiens_hsa003100.43839065
131Glioma_Homo sapiens_hsa052140.43360990
132Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.43079802
133Fat digestion and absorption_Homo sapiens_hsa049750.41979181
134Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.41462995
135Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40566821
136Homologous recombination_Homo sapiens_hsa034400.40442479
137Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39477430
138Oocyte meiosis_Homo sapiens_hsa041140.39043005
139Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38444220
140Cyanoamino acid metabolism_Homo sapiens_hsa004600.35619843
141Purine metabolism_Homo sapiens_hsa002300.34839957
142Steroid hormone biosynthesis_Homo sapiens_hsa001400.34649813
143Retinol metabolism_Homo sapiens_hsa008300.34599487
144Arachidonic acid metabolism_Homo sapiens_hsa005900.33924532
145Collecting duct acid secretion_Homo sapiens_hsa049660.31300743
146RNA transport_Homo sapiens_hsa030130.29862961

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