BRINP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)8.38828674
2neuron cell-cell adhesion (GO:0007158)8.25260218
3presynaptic membrane organization (GO:0097090)7.38212145
4postsynaptic membrane organization (GO:0001941)7.26065981
5vocalization behavior (GO:0071625)7.05255977
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act6.78397027
7neurotransmitter-gated ion channel clustering (GO:0072578)6.75544309
8regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)6.08185559
9gonadal mesoderm development (GO:0007506)5.97039792
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.72744626
11pyrimidine nucleobase catabolic process (GO:0006208)5.50604725
12regulation of glutamate receptor signaling pathway (GO:1900449)5.49631360
13cerebellar granule cell differentiation (GO:0021707)5.47626685
14protein localization to synapse (GO:0035418)5.28761009
15synaptic vesicle docking involved in exocytosis (GO:0016081)5.27622996
16positive regulation of synapse assembly (GO:0051965)5.02738235
17startle response (GO:0001964)4.79577610
18locomotory exploration behavior (GO:0035641)4.77968411
19regulation of short-term neuronal synaptic plasticity (GO:0048172)4.77121539
20nucleobase catabolic process (GO:0046113)4.66158736
21synaptic vesicle exocytosis (GO:0016079)4.65347151
22glutamate secretion (GO:0014047)4.50932240
23negative regulation of synaptic transmission, GABAergic (GO:0032229)4.50355511
24response to histamine (GO:0034776)4.49190818
25long-term synaptic potentiation (GO:0060291)4.45985764
26regulation of synaptic transmission, glutamatergic (GO:0051966)4.41573183
27positive regulation of synapse maturation (GO:0090129)4.41120010
28positive regulation of synaptic transmission, glutamatergic (GO:0051968)4.38956258
29regulation of synaptic vesicle exocytosis (GO:2000300)4.31809186
30gamma-aminobutyric acid signaling pathway (GO:0007214)4.28132208
31regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.24073137
32neuron-neuron synaptic transmission (GO:0007270)4.17342149
33ionotropic glutamate receptor signaling pathway (GO:0035235)4.14051156
34mechanosensory behavior (GO:0007638)4.11039308
35neuronal action potential propagation (GO:0019227)4.08858518
36synaptic transmission, glutamatergic (GO:0035249)4.05715473
37membrane assembly (GO:0071709)4.05476477
38glutamate receptor signaling pathway (GO:0007215)4.01271061
39regulation of excitatory postsynaptic membrane potential (GO:0060079)3.97703507
40auditory behavior (GO:0031223)3.97497291
41neurotransmitter secretion (GO:0007269)3.92842336
42regulation of synapse assembly (GO:0051963)3.91828461
43positive regulation of membrane potential (GO:0045838)3.91676455
44regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.90702420
45dendritic spine morphogenesis (GO:0060997)3.88748993
46regulation of synapse maturation (GO:0090128)3.87305762
47regulation of postsynaptic membrane potential (GO:0060078)3.82753463
48C4-dicarboxylate transport (GO:0015740)3.82488272
49regulation of synaptic vesicle transport (GO:1902803)3.71208844
50establishment of mitochondrion localization (GO:0051654)3.71170754
51positive regulation of neurotransmitter secretion (GO:0001956)3.69250637
52regulation of neuron projection regeneration (GO:0070570)3.69139696
53regulation of axon regeneration (GO:0048679)3.69139696
54layer formation in cerebral cortex (GO:0021819)3.60921847
55exploration behavior (GO:0035640)3.60480321
56righting reflex (GO:0060013)3.58033116
57neuron recognition (GO:0008038)3.56915308
58negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.54387570
59regulation of respiratory system process (GO:0044065)3.53726743
60G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.52961351
61gamma-aminobutyric acid transport (GO:0015812)3.47198165
62positive regulation of synaptic transmission (GO:0050806)3.37437475
63transmission of nerve impulse (GO:0019226)3.33642617
64synapse assembly (GO:0007416)3.31104923
65regulation of synapse structural plasticity (GO:0051823)3.27752505
66membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.27473429
67regulation of glutamate secretion (GO:0014048)3.26793283
68neurotransmitter transport (GO:0006836)3.25974560
69regulation of synapse organization (GO:0050807)3.25609275
70membrane hyperpolarization (GO:0060081)3.24197836
71response to auditory stimulus (GO:0010996)3.22487356
72regulation of synaptic plasticity (GO:0048167)3.20124173
73regulation of long-term neuronal synaptic plasticity (GO:0048169)3.15431627
74membrane depolarization (GO:0051899)3.13573045
75neurotransmitter uptake (GO:0001504)3.13300639
76axonal fasciculation (GO:0007413)3.12653641
77sodium ion export (GO:0071436)3.12634281
78amino acid import (GO:0043090)3.12041940
79behavioral response to cocaine (GO:0048148)3.11491830
80regulation of neurotransmitter secretion (GO:0046928)3.10811410
81striatum development (GO:0021756)3.09609939
82regulation of respiratory gaseous exchange (GO:0043576)3.08216174
83acidic amino acid transport (GO:0015800)3.07346335
84positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.06869241
85central nervous system projection neuron axonogenesis (GO:0021952)3.06387451
86positive regulation of neurotransmitter transport (GO:0051590)3.06328512
87cell differentiation in hindbrain (GO:0021533)3.03459420
88transferrin transport (GO:0033572)3.02225096
89learning (GO:0007612)3.00996229
90energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.00808740
91ATP hydrolysis coupled proton transport (GO:0015991)3.00808740
92synapse organization (GO:0050808)2.99465605
93regulation of dendritic spine morphogenesis (GO:0061001)2.98711485
94regulation of neuronal synaptic plasticity (GO:0048168)2.98583198
95regulation of neurotransmitter levels (GO:0001505)2.97462899
96regulation of synaptic transmission, GABAergic (GO:0032228)2.97327241
97synaptic vesicle maturation (GO:0016188)2.96891786
98positive regulation of synaptic transmission, GABAergic (GO:0032230)2.94706654
99cerebellar Purkinje cell differentiation (GO:0021702)2.94149072
100innervation (GO:0060384)2.92510282
101regulation of dendritic spine development (GO:0060998)2.92007884
102cochlea development (GO:0090102)2.90052912
103regulation of synaptic transmission (GO:0050804)2.89411211
104cell migration in hindbrain (GO:0021535)2.89320453
105intraspecies interaction between organisms (GO:0051703)2.88908043
106social behavior (GO:0035176)2.88908043
107negative regulation of dendrite morphogenesis (GO:0050774)2.88302715
108regulation of cardiac muscle cell contraction (GO:0086004)2.88055186
109long-term memory (GO:0007616)2.87809872
110dendritic spine organization (GO:0097061)2.86966197
111negative regulation of dendrite development (GO:2000171)2.86918841
112regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.84991306
113cellular response to ammonium ion (GO:0071242)2.84716650
114ferric iron transport (GO:0015682)2.83548843
115trivalent inorganic cation transport (GO:0072512)2.83548843
116cerebral cortex radially oriented cell migration (GO:0021799)2.83447851
117membrane depolarization during action potential (GO:0086010)2.83128092
118L-amino acid import (GO:0043092)2.81926362
119auditory receptor cell stereocilium organization (GO:0060088)2.81903069
120neuronal ion channel clustering (GO:0045161)2.81839174
121serotonin metabolic process (GO:0042428)2.77715064
122dendrite morphogenesis (GO:0048813)2.77228318
123L-glutamate transport (GO:0015813)2.74918739
124positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74821242
125negative regulation of heart rate (GO:0010459)2.73115840
126mitochondrion transport along microtubule (GO:0047497)2.70947795
127establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.70947795
128negative regulation of synaptic transmission (GO:0050805)2.69066291
129calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.67942988
130negative regulation of axon extension (GO:0030517)2.64579229
131positive regulation of mitochondrial fission (GO:0090141)2.61979222
132neuromuscular synaptic transmission (GO:0007274)2.60576864
133adult walking behavior (GO:0007628)2.58767504
134cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.58453933
135primary amino compound metabolic process (GO:1901160)2.58144438
136positive regulation of action potential (GO:0045760)2.57804945
137glycosphingolipid biosynthetic process (GO:0006688)2.56915775
138negative regulation of neurotransmitter transport (GO:0051589)2.55804046
139cellular potassium ion homeostasis (GO:0030007)2.53404381

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.43657191
2GBX2_23144817_ChIP-Seq_PC3_Human5.12760360
3TAF15_26573619_Chip-Seq_HEK293_Human3.17804365
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98410591
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.95510144
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.89665269
7CTBP2_25329375_ChIP-Seq_LNCAP_Human2.64583999
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54611413
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.51358200
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.49717973
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.47965213
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41257823
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.39582898
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.39388004
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.39388004
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36313526
17AR_21572438_ChIP-Seq_LNCaP_Human2.34214853
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.32277107
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.26465687
20CTBP1_25329375_ChIP-Seq_LNCAP_Human2.24385934
21REST_21632747_ChIP-Seq_MESCs_Mouse2.21209393
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.18420999
23MTF2_20144788_ChIP-Seq_MESCs_Mouse2.14001907
24SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.11583242
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.98080919
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.94502667
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93935261
28P300_19829295_ChIP-Seq_ESCs_Human1.93302242
29SMAD4_21799915_ChIP-Seq_A2780_Human1.92745031
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.92225637
31EZH2_27294783_Chip-Seq_ESCs_Mouse1.91499126
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.90173650
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.87263754
34FUS_26573619_Chip-Seq_HEK293_Human1.85966680
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83381984
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.82969349
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75281575
38REST_18959480_ChIP-ChIP_MESCs_Mouse1.73014240
39PIAS1_25552417_ChIP-Seq_VCAP_Human1.71361663
40SMAD3_21741376_ChIP-Seq_EPCs_Human1.67779537
41SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65586886
42BMI1_23680149_ChIP-Seq_NPCS_Mouse1.62707056
43CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61153869
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59868047
45DROSHA_22980978_ChIP-Seq_HELA_Human1.59713225
46OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.55686309
47RARB_27405468_Chip-Seq_BRAIN_Mouse1.53421671
48ER_23166858_ChIP-Seq_MCF-7_Human1.53096433
49SMAD_19615063_ChIP-ChIP_OVARY_Human1.51965690
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50961815
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.50342639
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.49155784
53AR_25329375_ChIP-Seq_VCAP_Human1.48752982
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47311612
55VDR_22108803_ChIP-Seq_LS180_Human1.47109757
56SOX2_21211035_ChIP-Seq_LN229_Gbm1.42435082
57STAT3_23295773_ChIP-Seq_U87_Human1.39649112
58NR3C1_21868756_ChIP-Seq_MCF10A_Human1.36788850
59RNF2_27304074_Chip-Seq_NSC_Mouse1.36624302
60ZNF274_21170338_ChIP-Seq_K562_Hela1.34146789
61IGF1R_20145208_ChIP-Seq_DFB_Human1.33313253
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30338667
63TCF4_23295773_ChIP-Seq_U87_Human1.28433689
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.27530694
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.26627942
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26084276
67TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25612035
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24703919
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.21100955
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21045550
71CBP_20019798_ChIP-Seq_JUKART_Human1.21045550
72EWS_26573619_Chip-Seq_HEK293_Human1.19970119
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19651457
74CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17950182
75NANOG_18555785_Chip-Seq_ESCs_Mouse1.17814997
76AHR_22903824_ChIP-Seq_MCF-7_Human1.16688295
77TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16684943
78JUN_21703547_ChIP-Seq_K562_Human1.16411908
79TAL1_26923725_Chip-Seq_HPCs_Mouse1.13827407
80KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13247840
81CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.13227983
82RUNX2_22187159_ChIP-Seq_PCA_Human1.12749137
83MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.11897662
84NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11520859
85PCGF2_27294783_Chip-Seq_ESCs_Mouse1.10749869
86ERG_21242973_ChIP-ChIP_JURKAT_Human1.10221561
87EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.08522338
88PRDM14_20953172_ChIP-Seq_ESCs_Human1.08282920
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08201757
90MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06220612
91SOX9_26525672_Chip-Seq_HEART_Mouse1.04886194
92TP53_18474530_ChIP-ChIP_U2OS_Human1.04695872
93E2F1_18555785_Chip-Seq_ESCs_Mouse1.04117212
94RING1B_27294783_Chip-Seq_ESCs_Mouse1.04012056
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01992432
96POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01949914
97TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01949914
98KDM2B_26808549_Chip-Seq_REH_Human1.01730188
99P53_22387025_ChIP-Seq_ESCs_Mouse1.01542774
100AR_19668381_ChIP-Seq_PC3_Human1.01122363
101RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.00550822
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.99838906
103P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99337145
104ZNF217_24962896_ChIP-Seq_MCF-7_Human0.98636058
105YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97727006
106BCAT_22108803_ChIP-Seq_LS180_Human0.97622044
107SUZ12_27294783_Chip-Seq_NPCs_Mouse0.97420522
108CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97220277
109ESR1_20079471_ChIP-ChIP_T-47D_Human0.96915705
110RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95693887
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95629685
112SALL1_21062744_ChIP-ChIP_HESCs_Human0.95329029
113E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.93274863

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.65499260
2MP0004859_abnormal_synaptic_plasticity4.35536450
3MP0003635_abnormal_synaptic_transmissio3.78118570
4MP0001968_abnormal_touch/_nociception3.65880082
5MP0009745_abnormal_behavioral_response3.56965966
6MP0002736_abnormal_nociception_after3.40419688
7MP0004270_analgesia3.34020379
8MP0009046_muscle_twitch3.16737890
9MP0002064_seizures3.14479275
10MP0002063_abnormal_learning/memory/cond3.04293126
11MP0002572_abnormal_emotion/affect_behav2.95757155
12MP0002735_abnormal_chemical_nociception2.55111809
13MP0002734_abnormal_mechanical_nocicepti2.54969431
14MP0002822_catalepsy2.54700319
15MP0002272_abnormal_nervous_system2.54161136
16MP0001486_abnormal_startle_reflex2.50073612
17MP0001501_abnormal_sleep_pattern2.44089866
18MP0002067_abnormal_sensory_capabilities2.42709322
19MP0001440_abnormal_grooming_behavior2.35198717
20MP0009780_abnormal_chondrocyte_physiolo2.25577176
21MP0005423_abnormal_somatic_nervous2.24490635
22MP0001188_hyperpigmentation2.17049011
23MP0005646_abnormal_pituitary_gland2.14411643
24MP0001984_abnormal_olfaction2.07593826
25MP0001529_abnormal_vocalization2.04572650
26MP0005645_abnormal_hypothalamus_physiol1.99989197
27MP0002557_abnormal_social/conspecific_i1.95126409
28MP0005171_absent_coat_pigmentation1.84735679
29MP0004742_abnormal_vestibular_system1.82813154
30MP0002184_abnormal_innervation1.80295736
31MP0002733_abnormal_thermal_nociception1.79588645
32MP0006276_abnormal_autonomic_nervous1.75045052
33MP0003879_abnormal_hair_cell1.73515733
34MP0004142_abnormal_muscle_tone1.72392314
35MP0001970_abnormal_pain_threshold1.71506760
36MP0000778_abnormal_nervous_system1.70854056
37MP0005386_behavior/neurological_phenoty1.68863010
38MP0004924_abnormal_behavior1.68863010
39MP0002876_abnormal_thyroid_physiology1.57649500
40MP0001502_abnormal_circadian_rhythm1.53134663
41MP0008569_lethality_at_weaning1.50192072
42MP0003787_abnormal_imprinting1.41768291
43MP0003122_maternal_imprinting1.40915276
44MP0004782_abnormal_surfactant_physiolog1.40302523
45MP0002066_abnormal_motor_capabilities/c1.35310765
46MP0005187_abnormal_penis_morphology1.34382190
47MP0003136_yellow_coat_color1.33995900
48MP0002837_dystrophic_cardiac_calcinosis1.33581924
49MP0003183_abnormal_peptide_metabolism1.30713820
50MP0002882_abnormal_neuron_morphology1.26661801
51MP0004147_increased_porphyrin_level1.25372463
52MP0004811_abnormal_neuron_physiology1.24480406
53MP0008877_abnormal_DNA_methylation1.22359042
54MP0000955_abnormal_spinal_cord1.21397039
55MP0004858_abnormal_nervous_system1.20711883
56MP0005248_abnormal_Harderian_gland1.17134136
57MP0004145_abnormal_muscle_electrophysio1.11997902
58MP0010386_abnormal_urinary_bladder1.11698458
59MP0001963_abnormal_hearing_physiology1.10089037
60MP0001905_abnormal_dopamine_level1.07080905
61MP0003633_abnormal_nervous_system1.05609020
62MP0004215_abnormal_myocardial_fiber1.01527996
63MP0005409_darkened_coat_color1.01050387
64MP0003329_amyloid_beta_deposits0.99193879
65MP0003011_delayed_dark_adaptation0.98961285
66MP0002152_abnormal_brain_morphology0.98895406
67MP0000026_abnormal_inner_ear0.95445481
68MP0005499_abnormal_olfactory_system0.94423087
69MP0005394_taste/olfaction_phenotype0.94423087
70MP0000631_abnormal_neuroendocrine_gland0.93721076
71MP0003631_nervous_system_phenotype0.93129302
72MP0005551_abnormal_eye_electrophysiolog0.92673517
73MP0000751_myopathy0.91875514
74MP0004085_abnormal_heartbeat0.90109864
75MP0003172_abnormal_lysosome_physiology0.88058812
76MP0004885_abnormal_endolymph0.84048060
77MP0002752_abnormal_somatic_nervous0.80697828
78MP0002229_neurodegeneration0.80496504
79MP0002069_abnormal_eating/drinking_beha0.79342814
80MP0003861_abnormal_nervous_system0.79152602
81MP0000427_abnormal_hair_cycle0.78999595
82MP0003698_abnormal_male_reproductive0.76877866
83MP0000538_abnormal_urinary_bladder0.76210150
84MP0001664_abnormal_digestion0.75662140
85MP0005410_abnormal_fertilization0.75514168
86MP0004043_abnormal_pH_regulation0.75308796
87MP0008874_decreased_physiological_sensi0.75126281
88MP0003634_abnormal_glial_cell0.69886241
89MP0001943_abnormal_respiration0.69368993
90MP0003938_abnormal_ear_development0.68312523
91MP0008872_abnormal_physiological_respon0.68032761
92MP0000647_abnormal_sebaceous_gland0.67819245
93MP0000013_abnormal_adipose_tissue0.67615882
94MP0000569_abnormal_digit_pigmentation0.67514593
95MP0003632_abnormal_nervous_system0.65639401
96MP0005535_abnormal_body_temperature0.65158684
97MP0004133_heterotaxia0.64477125
98MP0002090_abnormal_vision0.64157490
99MP0002160_abnormal_reproductive_system0.62720207
100MP0000534_abnormal_ureter_morphology0.61848648
101MP0005195_abnormal_posterior_eye0.60713436
102MP0002638_abnormal_pupillary_reflex0.59835069
103MP0003137_abnormal_impulse_conducting0.59694430
104MP0003941_abnormal_skin_development0.58869326
105MP0009697_abnormal_copulation0.57467878
106MP0001485_abnormal_pinna_reflex0.57391192
107MP0000920_abnormal_myelination0.56713971
108MP0010770_preweaning_lethality0.56352502
109MP0002082_postnatal_lethality0.56352502
110MP0003690_abnormal_glial_cell0.55808438
111MP0002653_abnormal_ependyma_morphology0.54905199
112MP0010769_abnormal_survival0.51097914
113MP0002909_abnormal_adrenal_gland0.50662541
114MP0004484_altered_response_of0.50132827
115MP0005253_abnormal_eye_physiology0.49722657
116MP0010768_mortality/aging0.48447838
117MP0001986_abnormal_taste_sensitivity0.48109320
118MP0002751_abnormal_autonomic_nervous0.46255648
119MP0001177_atelectasis0.45695647
120MP0005379_endocrine/exocrine_gland_phen0.45533347
121MP0003121_genomic_imprinting0.44437089

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.22204147
2Hyperventilation (HP:0002883)8.00916741
3Epileptic encephalopathy (HP:0200134)6.56535328
4Atonic seizures (HP:0010819)6.03894654
5Febrile seizures (HP:0002373)5.54724470
6Focal seizures (HP:0007359)5.36044817
7Broad-based gait (HP:0002136)4.68404174
8Absence seizures (HP:0002121)4.63513244
9Dialeptic seizures (HP:0011146)4.47220592
10Protruding tongue (HP:0010808)3.95547479
11Generalized tonic-clonic seizures (HP:0002069)3.87318598
12Visual hallucinations (HP:0002367)3.81800970
13Fetal akinesia sequence (HP:0001989)3.66847641
14Gaze-evoked nystagmus (HP:0000640)3.60672999
15Excessive salivation (HP:0003781)3.50170753
16Drooling (HP:0002307)3.50170753
17Myokymia (HP:0002411)3.44201539
18Blue irides (HP:0000635)3.42009857
19Inability to walk (HP:0002540)3.29639195
20Poor suck (HP:0002033)3.24263162
21Absent speech (HP:0001344)3.21754477
22Poor eye contact (HP:0000817)3.12132453
23Fair hair (HP:0002286)3.01648195
24Progressive cerebellar ataxia (HP:0002073)3.00012998
25Polyphagia (HP:0002591)2.87474595
26Abnormal social behavior (HP:0012433)2.87271011
27Impaired social interactions (HP:0000735)2.87271011
28Dysdiadochokinesis (HP:0002075)2.86020965
29Retinal dysplasia (HP:0007973)2.83237319
30Progressive inability to walk (HP:0002505)2.81926615
31Abnormal eating behavior (HP:0100738)2.74635534
32Akinesia (HP:0002304)2.72570251
33Generalized hypopigmentation of hair (HP:0011358)2.71790360
34Epileptiform EEG discharges (HP:0011182)2.70157689
35Sensory axonal neuropathy (HP:0003390)2.69303952
36Gait imbalance (HP:0002141)2.67871110
37Spastic gait (HP:0002064)2.64766629
38Ankle clonus (HP:0011448)2.64077464
39Abnormal hair whorl (HP:0010721)2.63600212
40Urinary urgency (HP:0000012)2.62031314
41Amyotrophic lateral sclerosis (HP:0007354)2.60084328
42Septo-optic dysplasia (HP:0100842)2.58806505
43Absent/shortened dynein arms (HP:0200106)2.56506346
44Dynein arm defect of respiratory motile cilia (HP:0012255)2.56506346
45Optic nerve hypoplasia (HP:0000609)2.50906126
46Truncal ataxia (HP:0002078)2.48874256
47Mutism (HP:0002300)2.48299324
48Lissencephaly (HP:0001339)2.48286860
49Amblyopia (HP:0000646)2.46096952
50Medial flaring of the eyebrow (HP:0010747)2.44428088
51Abnormality of salivation (HP:0100755)2.42823851
52True hermaphroditism (HP:0010459)2.41025182
53EEG with generalized epileptiform discharges (HP:0011198)2.39906474
54Congenital primary aphakia (HP:0007707)2.38431049
55Nephrogenic diabetes insipidus (HP:0009806)2.34381044
56Acute necrotizing encephalopathy (HP:0006965)2.32957972
57Hemiparesis (HP:0001269)2.31313623
58Hyperthyroidism (HP:0000836)2.31000940
59Status epilepticus (HP:0002133)2.27517126
60Dysmetric saccades (HP:0000641)2.25319662
61Megalencephaly (HP:0001355)2.24882151
62Impaired vibration sensation in the lower limbs (HP:0002166)2.23483183
63Hemiplegia (HP:0002301)2.22544866
64Generalized myoclonic seizures (HP:0002123)2.21600828
65Abnormal mitochondria in muscle tissue (HP:0008316)2.18672942
66Hypsarrhythmia (HP:0002521)2.14909748
67Anxiety (HP:0000739)2.13500023
68Nonprogressive disorder (HP:0003680)2.11862612
69Progressive macrocephaly (HP:0004481)2.09021693
70Pancreatic cysts (HP:0001737)2.08483161
71Morphological abnormality of the pyramidal tract (HP:0002062)2.06671297
72Esotropia (HP:0000565)2.04436013
73Abnormality of midbrain morphology (HP:0002418)2.03265415
74Molar tooth sign on MRI (HP:0002419)2.03265415
75Pachygyria (HP:0001302)2.02125631
76Pheochromocytoma (HP:0002666)2.01793908
77Abnormality of serine family amino acid metabolism (HP:0010894)2.01415967
78Abnormality of glycine metabolism (HP:0010895)2.01415967
79Congenital sensorineural hearing impairment (HP:0008527)2.00139015
80Narrow nasal bridge (HP:0000446)1.99220370
81Scanning speech (HP:0002168)1.98242645
82Hypoplasia of the brainstem (HP:0002365)1.98036570
83Aplasia/Hypoplasia of the brainstem (HP:0007362)1.98036570
84Specific learning disability (HP:0001328)1.96854634
85Pancreatic fibrosis (HP:0100732)1.96781905
86Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.96665721
87Type II lissencephaly (HP:0007260)1.94654245
88Clumsiness (HP:0002312)1.94294170
89Open mouth (HP:0000194)1.92431861
90Urinary bladder sphincter dysfunction (HP:0002839)1.92312178
91Atrophy/Degeneration involving motor neurons (HP:0007373)1.92070131
92Hypoventilation (HP:0002791)1.89879363
93Ulnar claw (HP:0001178)1.89482022
94Spastic tetraplegia (HP:0002510)1.89362706
95Thickened helices (HP:0000391)1.88984922
96Impaired vibratory sensation (HP:0002495)1.88871610
97Abnormality of the corticospinal tract (HP:0002492)1.87857302
98Nephronophthisis (HP:0000090)1.87707449
99Hyperglycinemia (HP:0002154)1.86990720
100Failure to thrive in infancy (HP:0001531)1.86741758
101Abnormality of binocular vision (HP:0011514)1.86503423
102Diplopia (HP:0000651)1.86503423
103Degeneration of the lateral corticospinal tracts (HP:0002314)1.86228420
104Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.86228420
105Occipital encephalocele (HP:0002085)1.85712215
106Lower limb muscle weakness (HP:0007340)1.85239197
107Hypoplasia of the corpus callosum (HP:0002079)1.84986922
108Neuroendocrine neoplasm (HP:0100634)1.84355996
109Astrocytoma (HP:0009592)1.84328875
110Abnormality of the astrocytes (HP:0100707)1.84328875
111Aplasia/Hypoplasia of the tibia (HP:0005772)1.83562501
112Postaxial hand polydactyly (HP:0001162)1.83073917
113Gastroesophageal reflux (HP:0002020)1.82820056
114Sensorimotor neuropathy (HP:0007141)1.81726619
115Dysmetria (HP:0001310)1.81428875
116Mitochondrial inheritance (HP:0001427)1.80332068
117Cortical dysplasia (HP:0002539)1.80191856
118Split foot (HP:0001839)1.80001156
119Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.78990537
120Sleep apnea (HP:0010535)1.77848156
121Abnormality of the labia minora (HP:0012880)1.77520240
122Widely spaced teeth (HP:0000687)1.75802618
123Diminished movement (HP:0002374)1.75451434
124Limb dystonia (HP:0002451)1.75001642
125Broad foot (HP:0001769)1.74549088
126Short tibia (HP:0005736)1.74543595
127Optic disc pallor (HP:0000543)1.74502490
128Termporal pattern (HP:0011008)1.73816651
129Insidious onset (HP:0003587)1.73816651
130Heterochromia iridis (HP:0001100)1.73608776
131Peripheral hypomyelination (HP:0007182)1.73544370
132Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.73463769
133Hyperglycinuria (HP:0003108)1.72711130
134Postnatal microcephaly (HP:0005484)1.72366182
135Incomplete penetrance (HP:0003829)1.71745815
136Action tremor (HP:0002345)1.71404332
137Genital tract atresia (HP:0001827)1.70923416
138Stereotypic behavior (HP:0000733)1.70680848
139Gait ataxia (HP:0002066)1.70278447
140Depression (HP:0000716)1.69487274
141Abnormality of the septum pellucidum (HP:0007375)1.68264803
142Vaginal atresia (HP:0000148)1.67119178
143Absent septum pellucidum (HP:0001331)1.66853783
144Poor coordination (HP:0002370)1.66758475
145Acute encephalopathy (HP:0006846)1.65475995
146Impaired smooth pursuit (HP:0007772)1.65272390
147Neurofibrillary tangles (HP:0002185)1.65204501
148Oligodactyly (hands) (HP:0001180)1.63985939
149Intellectual disability, severe (HP:0010864)1.63036671
150Neoplasm of the peripheral nervous system (HP:0100007)1.62964751

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK9.13673038
2NTRK33.58779607
3MAP3K123.33923891
4TNIK2.97594145
5MAP2K72.92737802
6MAP3K42.85806328
7EPHA42.79802297
8CCNB12.51934754
9DAPK22.47706166
10CDK192.19791886
11DYRK22.07359989
12AKT31.97650214
13PLK21.90211430
14PRPF4B1.88528411
15MAP2K41.81238391
16DAPK11.71053480
17MARK11.67165174
18NTRK21.54613180
19PINK11.53924541
20CSNK1G31.44276872
21MUSK1.41527265
22OXSR11.41237750
23MAPK131.40869156
24CSNK1A1L1.40302567
25TRIM281.37202384
26CAMKK21.37177828
27MKNK21.36504100
28PAK31.35873422
29PNCK1.31807614
30DYRK31.22258838
31SIK31.22226294
32CSNK1G11.19164703
33ERBB31.18526653
34MAP3K91.17907237
35MINK11.16468128
36EPHA31.13202410
37SIK21.11203244
38GRK51.10532001
39MAP4K21.04269125
40PRKCG0.99110025
41CDK50.96641746
42CAMK2A0.96046113
43PRKD30.95891492
44PHKG20.94253964
45PHKG10.94253964
46STK390.92860434
47TSSK60.90518309
48MAPK70.87388193
49PAK60.81376433
50TESK10.80872215
51NEK60.80162584
52TNK20.79795007
53SGK20.78934215
54ERBB40.77431580
55CDK30.77273609
56TAOK10.76628574
57SGK2230.76223250
58SGK4940.76223250
59BCR0.76053719
60RIPK40.73887632
61CAMK40.73827086
62CAMK2B0.71649847
63FES0.71282274
64PRKCE0.69793564
65TYRO30.69385253
66CAMKK10.67741233
67PTK2B0.66529361
68PDK20.66438902
69MAPK120.66424945
70DYRK1B0.65508139
71CDK180.64373862
72FRK0.63991335
73FGR0.63214020
74KSR10.62385534
75ADRBK10.59543319
76NME10.59184630
77CDK150.57472060
78LIMK10.57368281
79BCKDK0.56964300
80SGK10.56652636
81RPS6KA40.56646798
82STK240.55990920
83INSRR0.55754748
84WNK40.55735362
85STK110.55035759
86PBK0.54987837
87PDK40.54470084
88PDK30.54470084
89NTRK10.54045465
90BMPR20.53459503
91CAMK10.52468785
92CDK140.50140778
93DAPK30.48488317
94ERBB20.48132365
95CDK11A0.47497103
96OBSCN0.47103811
97ROCK10.44478592
98PDGFRA0.43646420
99MYLK0.43610683
100CSNK1D0.42966205
101PIK3CA0.42457390
102UHMK10.41294959
103SRPK10.40384938
104MKNK10.40027709
105STK380.39032048
106FER0.38930278
107CAMK2D0.38721621
108YES10.38411113
109BRAF0.38408818
110RPS6KB10.38389910
111PRKCI0.38022633
112DYRK1A0.37591172
113ROCK20.37097758
114GRK70.35830109
115SGK30.35711597
116CSNK1G20.35578315
117PRKACA0.34891530
118CAMK2G0.34582275
119ADRBK20.34007203
120MAPK100.33282603
121CSNK1E0.33112975
122WNK30.32785171
123BMPR1B0.32544581
124PKN10.32200214
125RPS6KA30.30742481
126GSK3B0.28129759
127GRK60.26517230
128MAPK90.25529275
129CAMK1G0.25337555
130PRKCA0.25256271
131PRKCB0.24404682
132PRKG10.23091089
133PRKCZ0.21823968
134CSNK1A10.21599999
135PRKACB0.21591952
136MAPK40.21445272

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.81210091
2Synaptic vesicle cycle_Homo sapiens_hsa047213.95479810
3Collecting duct acid secretion_Homo sapiens_hsa049663.20572472
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.10433142
5Morphine addiction_Homo sapiens_hsa050322.76578723
6GABAergic synapse_Homo sapiens_hsa047272.70173697
7Olfactory transduction_Homo sapiens_hsa047402.52952793
8Glutamatergic synapse_Homo sapiens_hsa047242.38542588
9Circadian entrainment_Homo sapiens_hsa047132.38305806
10Amphetamine addiction_Homo sapiens_hsa050312.18873942
11Long-term potentiation_Homo sapiens_hsa047202.16517418
12Steroid biosynthesis_Homo sapiens_hsa001002.03802661
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.00412611
14Taste transduction_Homo sapiens_hsa047421.99873502
15Serotonergic synapse_Homo sapiens_hsa047261.95124615
16Oxidative phosphorylation_Homo sapiens_hsa001901.91780607
17Dopaminergic synapse_Homo sapiens_hsa047281.89202743
18Vibrio cholerae infection_Homo sapiens_hsa051101.85736151
19Salivary secretion_Homo sapiens_hsa049701.85666850
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.84896259
21Long-term depression_Homo sapiens_hsa047301.83704949
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.79495691
23Insulin secretion_Homo sapiens_hsa049111.72153987
24Renin secretion_Homo sapiens_hsa049241.67087053
25Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.65323953
26Calcium signaling pathway_Homo sapiens_hsa040201.61739619
27Gastric acid secretion_Homo sapiens_hsa049711.56809371
28Cholinergic synapse_Homo sapiens_hsa047251.51569025
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.48501787
30Oxytocin signaling pathway_Homo sapiens_hsa049211.47866255
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.39629996
32Cardiac muscle contraction_Homo sapiens_hsa042601.31237971
33Cocaine addiction_Homo sapiens_hsa050301.29983328
34Axon guidance_Homo sapiens_hsa043601.29671126
35Aldosterone synthesis and secretion_Homo sapiens_hsa049251.27422786
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25666045
37Gap junction_Homo sapiens_hsa045401.23629271
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22560258
39Alzheimers disease_Homo sapiens_hsa050101.20077482
40GnRH signaling pathway_Homo sapiens_hsa049121.12727008
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12300806
42Nitrogen metabolism_Homo sapiens_hsa009101.12133565
43Fatty acid metabolism_Homo sapiens_hsa012121.11390915
44Parkinsons disease_Homo sapiens_hsa050121.11257390
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09294350
46Rheumatoid arthritis_Homo sapiens_hsa053231.08794239
47Phototransduction_Homo sapiens_hsa047441.06157846
48ErbB signaling pathway_Homo sapiens_hsa040120.99895001
49Histidine metabolism_Homo sapiens_hsa003400.95065835
50cAMP signaling pathway_Homo sapiens_hsa040240.92598584
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91667817
52Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.90094463
53Propanoate metabolism_Homo sapiens_hsa006400.89273052
54Dilated cardiomyopathy_Homo sapiens_hsa054140.88911025
55Glioma_Homo sapiens_hsa052140.85368500
56Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.83786675
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83142991
58Circadian rhythm_Homo sapiens_hsa047100.81688015
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80793825
60Bile secretion_Homo sapiens_hsa049760.79793581
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79558360
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78295424
63Phagosome_Homo sapiens_hsa041450.75994222
64Peroxisome_Homo sapiens_hsa041460.75764435
65Estrogen signaling pathway_Homo sapiens_hsa049150.75737573
66Huntingtons disease_Homo sapiens_hsa050160.75580606
67Tryptophan metabolism_Homo sapiens_hsa003800.74147801
68Arginine and proline metabolism_Homo sapiens_hsa003300.73132248
69Caffeine metabolism_Homo sapiens_hsa002320.72689181
70MAPK signaling pathway_Homo sapiens_hsa040100.71691197
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.71132050
72Melanogenesis_Homo sapiens_hsa049160.70986908
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70264511
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70161385
75alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.68686434
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.68411594
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67526553
78Phenylalanine metabolism_Homo sapiens_hsa003600.66969981
79beta-Alanine metabolism_Homo sapiens_hsa004100.66047147
80PPAR signaling pathway_Homo sapiens_hsa033200.64828097
81Type I diabetes mellitus_Homo sapiens_hsa049400.63706578
82Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63533000
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.63412466
84Ras signaling pathway_Homo sapiens_hsa040140.57658589
85Type II diabetes mellitus_Homo sapiens_hsa049300.57351850
86AMPK signaling pathway_Homo sapiens_hsa041520.57218334
87Melanoma_Homo sapiens_hsa052180.56024555
88Fat digestion and absorption_Homo sapiens_hsa049750.55420156
89Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54316970
90Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53760102
91Linoleic acid metabolism_Homo sapiens_hsa005910.52562215
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51965997
93Sphingolipid metabolism_Homo sapiens_hsa006000.51340176
94Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.50060228
95Pancreatic secretion_Homo sapiens_hsa049720.49107102
96Mineral absorption_Homo sapiens_hsa049780.48682679
97Fatty acid biosynthesis_Homo sapiens_hsa000610.48549781
98Choline metabolism in cancer_Homo sapiens_hsa052310.45784367
99Lysine degradation_Homo sapiens_hsa003100.44906909
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43724802
101ABC transporters_Homo sapiens_hsa020100.43139830
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43072201
103Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42715464
104Alcoholism_Homo sapiens_hsa050340.42602611
105Ether lipid metabolism_Homo sapiens_hsa005650.42238024
106Dorso-ventral axis formation_Homo sapiens_hsa043200.42122168
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41250283
108Fatty acid degradation_Homo sapiens_hsa000710.41131488
109Ovarian steroidogenesis_Homo sapiens_hsa049130.41021064
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.40782406
111Arginine biosynthesis_Homo sapiens_hsa002200.40345790
112Vitamin B6 metabolism_Homo sapiens_hsa007500.39153549
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.38824829
114Biosynthesis of amino acids_Homo sapiens_hsa012300.38671397
115Other glycan degradation_Homo sapiens_hsa005110.38149623
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37832282
117Rap1 signaling pathway_Homo sapiens_hsa040150.37704101
118Fructose and mannose metabolism_Homo sapiens_hsa000510.37164835
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36955981
120Butanoate metabolism_Homo sapiens_hsa006500.33721996
121Glucagon signaling pathway_Homo sapiens_hsa049220.33532504
122Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33106525
123SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33002966
124Oocyte meiosis_Homo sapiens_hsa041140.28948024
125Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.28890671
126Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.28365801
127Fatty acid elongation_Homo sapiens_hsa000620.27925030
128Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27339967
129African trypanosomiasis_Homo sapiens_hsa051430.26992240
130Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26181323
131Regulation of autophagy_Homo sapiens_hsa041400.26163516
132Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.25825536
133Wnt signaling pathway_Homo sapiens_hsa043100.24595489
134Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24372574
135Thyroid hormone synthesis_Homo sapiens_hsa049180.22254908
136Glycerophospholipid metabolism_Homo sapiens_hsa005640.19710542

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