BEND7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.94888538
2L-phenylalanine catabolic process (GO:0006559)5.94888538
3L-phenylalanine metabolic process (GO:0006558)5.74591829
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.74591829
5aromatic amino acid family catabolic process (GO:0009074)4.66035206
6intestinal cholesterol absorption (GO:0030299)4.24930175
7cysteine metabolic process (GO:0006534)4.24119101
8bile acid and bile salt transport (GO:0015721)4.17228889
9sulfur amino acid catabolic process (GO:0000098)4.16680516
10COPI coating of Golgi vesicle (GO:0048205)3.92979740
11Golgi transport vesicle coating (GO:0048200)3.92979740
12surfactant homeostasis (GO:0043129)3.90697386
13endocrine pancreas development (GO:0031018)3.81915371
14drug catabolic process (GO:0042737)3.74035908
15bile acid metabolic process (GO:0008206)3.69717621
16lysine metabolic process (GO:0006553)3.68992030
17lysine catabolic process (GO:0006554)3.68992030
18tyrosine metabolic process (GO:0006570)3.66882810
19aromatic amino acid family metabolic process (GO:0009072)3.65444748
20drug transmembrane transport (GO:0006855)3.63970004
21glyoxylate metabolic process (GO:0046487)3.63416147
22tryptophan metabolic process (GO:0006568)3.60734439
23indole-containing compound catabolic process (GO:0042436)3.59804376
24indolalkylamine catabolic process (GO:0046218)3.59804376
25tryptophan catabolic process (GO:0006569)3.59804376
26regulation of bile acid biosynthetic process (GO:0070857)3.55307380
27kynurenine metabolic process (GO:0070189)3.54539671
28intestinal absorption (GO:0050892)3.53567277
29cellular ketone body metabolic process (GO:0046950)3.49776433
30peptidyl-glutamic acid carboxylation (GO:0017187)3.48297186
31protein carboxylation (GO:0018214)3.48297186
32triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.46216013
33COPII vesicle coating (GO:0048208)3.45937659
34bile acid biosynthetic process (GO:0006699)3.44039136
35glandular epithelial cell differentiation (GO:0002067)3.42716577
36alpha-linolenic acid metabolic process (GO:0036109)3.42400569
37peptide hormone processing (GO:0016486)3.39606475
38homocysteine metabolic process (GO:0050667)3.37863872
39acylglycerol homeostasis (GO:0055090)3.34036461
40triglyceride homeostasis (GO:0070328)3.34036461
41toxin metabolic process (GO:0009404)3.31168845
42high-density lipoprotein particle remodeling (GO:0034375)3.30385436
43cholesterol efflux (GO:0033344)3.28070823
44indolalkylamine metabolic process (GO:0006586)3.26168701
45short-chain fatty acid metabolic process (GO:0046459)3.22879087
46urea cycle (GO:0000050)3.21561624
47urea metabolic process (GO:0019627)3.21561624
48protein-lipid complex remodeling (GO:0034368)3.17864819
49macromolecular complex remodeling (GO:0034367)3.17864819
50plasma lipoprotein particle remodeling (GO:0034369)3.17864819
51negative regulation of digestive system process (GO:0060457)3.15134559
52alkaloid metabolic process (GO:0009820)3.11704298
53fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.06182580
54regulation of cholesterol homeostasis (GO:2000188)3.05566767
55complement activation, alternative pathway (GO:0006957)3.03816146
56serine family amino acid catabolic process (GO:0009071)3.02423501
57reverse cholesterol transport (GO:0043691)3.02142899
58exogenous drug catabolic process (GO:0042738)3.02029111
59fatty acid beta-oxidation (GO:0006635)3.01591737
60fatty acid oxidation (GO:0019395)3.00707820
61hormone catabolic process (GO:0042447)3.00427440
62epoxygenase P450 pathway (GO:0019373)3.00210516
63drug metabolic process (GO:0017144)2.99770289
64positive regulation of fatty acid beta-oxidation (GO:0032000)2.99247504
65nitrogen cycle metabolic process (GO:0071941)2.98952381
66coenzyme catabolic process (GO:0009109)2.98885038
67glutamate metabolic process (GO:0006536)2.96957595
68phospholipid efflux (GO:0033700)2.96699909
69alpha-amino acid catabolic process (GO:1901606)2.96692669
70ketone body metabolic process (GO:1902224)2.96159642
71regulation of triglyceride catabolic process (GO:0010896)2.95994588
72regulation of protein activation cascade (GO:2000257)2.94697424
73fatty acid catabolic process (GO:0009062)2.94438695
74embryonic retina morphogenesis in camera-type eye (GO:0060059)2.93786170
75lipid oxidation (GO:0034440)2.93071847
76cellular amino acid catabolic process (GO:0009063)2.91819789
77chemical homeostasis within a tissue (GO:0048875)2.91298696
78plasma lipoprotein particle assembly (GO:0034377)2.90510960
79cellular modified amino acid catabolic process (GO:0042219)2.89800077
80positive regulation of glycolytic process (GO:0045821)2.89670983
81synapsis (GO:0007129)2.88411419
82monocarboxylic acid catabolic process (GO:0072329)2.87707885
83flavonoid metabolic process (GO:0009812)2.87634174
84very-low-density lipoprotein particle assembly (GO:0034379)2.86160079
85regulation of fibrinolysis (GO:0051917)2.85546545
86amino-acid betaine metabolic process (GO:0006577)2.85433069
87transcytosis (GO:0045056)2.83938208
88regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.82821969
89negative regulation of fibrinolysis (GO:0051918)2.82646875
90low-density lipoprotein particle remodeling (GO:0034374)2.79661421
91drug transport (GO:0015893)2.78933801
92auditory receptor cell differentiation (GO:0042491)2.77593335
93regulation of complement activation (GO:0030449)2.76719582
94peptide catabolic process (GO:0043171)2.75199645
95epithelial cilium movement (GO:0003351)2.74910396
96L-alpha-amino acid transmembrane transport (GO:1902475)2.74663528
97organic acid catabolic process (GO:0016054)2.74529727
98carboxylic acid catabolic process (GO:0046395)2.74529727
99regulation of cilium movement (GO:0003352)2.71563068
100benzene-containing compound metabolic process (GO:0042537)2.70986215
101phospholipid homeostasis (GO:0055091)2.70474819
102regulation of cholesterol esterification (GO:0010872)2.69142528
103plasma lipoprotein particle organization (GO:0071827)2.67821938
104lipoprotein metabolic process (GO:0042157)2.67620539
105cholesterol homeostasis (GO:0042632)2.66793462
106sterol homeostasis (GO:0055092)2.65355212
107positive regulation of lipoprotein lipase activity (GO:0051006)2.65014725
108nephron tubule morphogenesis (GO:0072078)2.58782595
109nephron epithelium morphogenesis (GO:0072088)2.58782595
110phenol-containing compound catabolic process (GO:0019336)2.52280163
111piRNA metabolic process (GO:0034587)2.51571800
112cellular glucuronidation (GO:0052695)2.47863930
113thyroid hormone metabolic process (GO:0042403)2.46787828
114regulation of type B pancreatic cell apoptotic process (GO:2000674)2.46396661
115macroautophagy (GO:0016236)2.42293040
116regulation of glucokinase activity (GO:0033131)2.39323459
117regulation of hexokinase activity (GO:1903299)2.39323459
118establishment of protein localization to Golgi (GO:0072600)2.39079109
119male meiosis I (GO:0007141)2.33762649
120regulation of lipoprotein metabolic process (GO:0050746)2.31546172
121cilium movement (GO:0003341)2.31244978
122chromosome organization involved in meiosis (GO:0070192)2.30167785
123glucuronate metabolic process (GO:0019585)2.29220309
124uronic acid metabolic process (GO:0006063)2.29220309
125urate metabolic process (GO:0046415)2.28231548
126negative regulation of cytosolic calcium ion concentration (GO:0051481)2.26402274
127protein targeting to Golgi (GO:0000042)2.26197159
128negative regulation of protein localization to cell surface (GO:2000009)2.25108401
129epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.24415672
130angiotensin maturation (GO:0002003)2.22863775
131thyroid hormone generation (GO:0006590)2.19952354
132type B pancreatic cell development (GO:0003323)2.19724821
133peristalsis (GO:0030432)2.19081829
134cilium assembly (GO:0042384)2.18722613
135sperm motility (GO:0030317)2.18611659
136retrograde transport, vesicle recycling within Golgi (GO:0000301)2.18495374
137male meiosis (GO:0007140)2.15989343
138somite rostral/caudal axis specification (GO:0032525)2.15835404
139cilium organization (GO:0044782)2.15624342
140positive regulation of meiosis (GO:0045836)2.14862449
141kidney morphogenesis (GO:0060993)2.14125813
142artery smooth muscle contraction (GO:0014824)2.14107835
143DNA methylation involved in gamete generation (GO:0043046)2.13898403
144nonmotile primary cilium assembly (GO:0035058)2.13842249
145regulation of guanylate cyclase activity (GO:0031282)2.08716065
146protein localization to Golgi apparatus (GO:0034067)2.08438174
147tonic smooth muscle contraction (GO:0014820)2.07327975
148motile cilium assembly (GO:0044458)2.07142928
149axonemal dynein complex assembly (GO:0070286)2.06335961
150neurotransmitter catabolic process (GO:0042135)2.05977852
151positive regulation of meiotic cell cycle (GO:0051446)2.05568990
152brain morphogenesis (GO:0048854)2.05094379
153mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.05003078
154renal tubule morphogenesis (GO:0061333)2.04038256
155arginine metabolic process (GO:0006525)2.03535045
156regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.03291787
157peroxisome fission (GO:0016559)2.02685771
158vascular smooth muscle contraction (GO:0014829)2.02276188
159pattern specification involved in kidney development (GO:0061004)1.99208256
160acrosome reaction (GO:0007340)1.98268395
161inner ear receptor cell differentiation (GO:0060113)1.97525918
162regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)1.96454842
163negative regulation of hormone metabolic process (GO:0032351)1.96269678
164pancreas development (GO:0031016)1.96213110
165digestion (GO:0007586)1.94168951
166nephron tubule formation (GO:0072079)1.93865227
167axoneme assembly (GO:0035082)1.92395312
168photoreceptor cell maintenance (GO:0045494)1.92364074
169synaptonemal complex organization (GO:0070193)1.91494555
170hair cell differentiation (GO:0035315)1.91400408
171synaptonemal complex assembly (GO:0007130)1.91178062
172peptidyl-glutamic acid modification (GO:0018200)1.90770602
173protein polyglutamylation (GO:0018095)1.90650677
174cellular component assembly involved in morphogenesis (GO:0010927)1.89719686
175omega-hydroxylase P450 pathway (GO:0097267)1.89416533
176response to muscle activity (GO:0014850)1.88809185
177cilium morphogenesis (GO:0060271)1.88597738

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.87314306
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.22642136
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.42456790
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.39818574
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.63535136
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.59809665
7EGR1_23403033_ChIP-Seq_LIVER_Mouse3.58470408
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.92189646
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.74206046
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.66336695
11GBX2_23144817_ChIP-Seq_PC3_Human2.32989130
12GATA1_22025678_ChIP-Seq_K562_Human2.24692210
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.21718836
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.19398278
15CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.12398810
16IGF1R_20145208_ChIP-Seq_DFB_Human2.08533521
17SOX2_27498859_Chip-Seq_STOMACH_Mouse2.05953001
18FUS_26573619_Chip-Seq_HEK293_Human2.01673587
19ZNF274_21170338_ChIP-Seq_K562_Hela1.92174186
20CTBP2_25329375_ChIP-Seq_LNCAP_Human1.90678116
21FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.88933134
22CBX2_27304074_Chip-Seq_ESCs_Mouse1.86780978
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.81675768
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.78330541
25ER_23166858_ChIP-Seq_MCF-7_Human1.74044540
26SALL1_21062744_ChIP-ChIP_HESCs_Human1.73839291
27P300_19829295_ChIP-Seq_ESCs_Human1.72753331
28* SMAD4_21799915_ChIP-Seq_A2780_Human1.70998587
29* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.63796269
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.63554557
31ESR1_21235772_ChIP-Seq_MCF-7_Human1.62237195
32FOXA2_19822575_ChIP-Seq_HepG2_Human1.61347267
33MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59780029
34HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.55451850
35TRIM28_21343339_ChIP-Seq_HEK293_Human1.54526896
36EZH2_22144423_ChIP-Seq_EOC_Human1.53144868
37* AR_25329375_ChIP-Seq_VCAP_Human1.51085631
38SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.50798193
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49891666
40GATA4_25053715_ChIP-Seq_YYC3_Human1.49530718
41STAT3_23295773_ChIP-Seq_U87_Human1.49037540
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.46944079
43FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.44912404
44ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.42181886
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.40585380
46TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40036828
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38148698
48CLOCK_20551151_ChIP-Seq_293T_Human1.37793820
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37744554
50UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.37215493
51PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36295334
52ESR2_21235772_ChIP-Seq_MCF-7_Human1.36161070
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35547389
54TAF15_26573619_Chip-Seq_HEK293_Human1.34382408
55RNF2_27304074_Chip-Seq_NSC_Mouse1.34177442
56TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.32407540
57KLF5_20875108_ChIP-Seq_MESCs_Mouse1.32281892
58SOX2_20726797_ChIP-Seq_SW620_Human1.31493811
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30884976
60CBP_20019798_ChIP-Seq_JUKART_Human1.30884976
61CDX2_20551321_ChIP-Seq_CACO-2_Human1.28599384
62TCF4_23295773_ChIP-Seq_U87_Human1.28434631
63BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.27622599
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.27112287
65ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25083974
66NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24260612
67TBL1_22424771_ChIP-Seq_293T_Human1.23108802
68EWS_26573619_Chip-Seq_HEK293_Human1.22687436
69RBPJ_22232070_ChIP-Seq_NCS_Mouse1.21485390
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.20480392
71TCF4_18268006_ChIP-ChIP_LS174T_Human1.20382269
72CJUN_26792858_Chip-Seq_BT549_Human1.19943440
73TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18657965
74FOXA1_25552417_ChIP-Seq_VCAP_Human1.18307031
75CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17781370
76STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17523966
77* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17128358
78DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15724005
79SMAD4_21741376_ChIP-Seq_EPCs_Human1.15548890
80EZH2_27304074_Chip-Seq_ESCs_Mouse1.13874534
81* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13564410
82EED_16625203_ChIP-ChIP_MESCs_Mouse1.13232999
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11767436
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11767436
85RUNX2_22187159_ChIP-Seq_PCA_Human1.09496220
86ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.09448381
87HNF4A_19822575_ChIP-Seq_HepG2_Human1.08728023
88* NFYB_21822215_ChIP-Seq_K562_Human1.08451561
89PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.07330527
90ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07235921
91RXR_22108803_ChIP-Seq_LS180_Human1.06334581
92NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06320964
93* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.06308071
94TP53_18474530_ChIP-ChIP_U2OS_Human1.05082828
95NANOG_19829295_ChIP-Seq_ESCs_Human1.04867696
96SOX2_19829295_ChIP-Seq_ESCs_Human1.04867696
97PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.04476917
98* NFYA_21822215_ChIP-Seq_K562_Human1.03957375
99ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.03211028
100SMAD3_21741376_ChIP-Seq_HESCs_Human1.02583649
101* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01660345
102HTT_18923047_ChIP-ChIP_STHdh_Human1.01512981
103ETV1_20927104_ChIP-Seq_GIST48_Human1.00946630
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.00509836
105* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00457023
106* PHF8_20622853_ChIP-Seq_HELA_Human0.99916146
107P53_22127205_ChIP-Seq_FIBROBLAST_Human0.98397245
108TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98083771
109* HNFA_21074721_ChIP-Seq_CACO-2_Human0.97503781
110JARID2_20064375_ChIP-Seq_MESCs_Mouse0.97128948
111* NANOG_18555785_Chip-Seq_ESCs_Mouse0.96740356
112TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96169982
113GATA6_25053715_ChIP-Seq_YYC3_Human0.93485120
114ESR1_20079471_ChIP-ChIP_T-47D_Human0.90725104
115GATA3_24758297_ChIP-Seq_MCF-7_Human0.88704964
116MTF2_20144788_ChIP-Seq_MESCs_Mouse0.86767862
117THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86698571
118PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84070725
119VDR_22108803_ChIP-Seq_LS180_Human0.83622177
120RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82723192
121BCAT_22108803_ChIP-Seq_LS180_Human0.80026656
122* AR_20517297_ChIP-Seq_VCAP_Human0.77389052
123TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76950479
124SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.76651495
125AHR_22903824_ChIP-Seq_MCF-7_Human0.76005189
126SMAD4_21741376_ChIP-Seq_HESCs_Human0.75883508
127NFIB_24661679_ChIP-Seq_LUNG_Mouse0.75575074
128GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75415500
129SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.74293317
130FOXM1_26456572_ChIP-Seq_MCF-7_Human0.73981439
131EZH2_27294783_Chip-Seq_ESCs_Mouse0.73640109
132OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.73333723
133SALL4_18804426_ChIP-ChIP_XEN_Mouse0.72851927
134DROSHA_22980978_ChIP-Seq_HELA_Human0.72459576
135ISL1_27105846_Chip-Seq_CPCs_Mouse0.72290144
136ETV2_25802403_ChIP-Seq_MESCs_Mouse0.71689347
137GATA2_21666600_ChIP-Seq_HMVEC_Human0.71246334
138AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.71144301
139BMI1_23680149_ChIP-Seq_NPCS_Mouse0.70778179
140FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.69410208
141EP300_21415370_ChIP-Seq_HL-1_Mouse0.68232835
142NR3C1_21868756_ChIP-Seq_MCF10A_Human0.67264632
143CTCF_27219007_Chip-Seq_Bcells_Human0.67236505
144IRF1_19129219_ChIP-ChIP_H3396_Human0.67159027
145SOX2_21211035_ChIP-Seq_LN229_Gbm0.66096660
146SUZ12_27294783_Chip-Seq_ESCs_Mouse0.65136060
147ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.65080219
148CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.64902782
149EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.64716863
150GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.64301067
151REST_21632747_ChIP-Seq_MESCs_Mouse0.64067037
152SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.63408790
153JARID2_20075857_ChIP-Seq_MESCs_Mouse0.63182637
154CDX2_22108803_ChIP-Seq_LS180_Human0.63057620
155SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.62873947
156ARNT_22903824_ChIP-Seq_MCF-7_Human0.62654605
157FOXO3_23340844_ChIP-Seq_DLD1_Human0.62436735
158RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.61545717
159TCF4_22108803_ChIP-Seq_LS180_Human0.61382575
160TBX20_22080862_ChIP-Seq_HEART_Mouse0.61024753
161TBX20_22328084_ChIP-Seq_HEART_Mouse0.61024753
162CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.60965173
163WT1_25993318_ChIP-Seq_PODOCYTE_Human0.60360677
164RAD21_21589869_ChIP-Seq_MESCs_Mouse0.60287197

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.11403283
2MP0005360_urolithiasis5.53219650
3MP0005365_abnormal_bile_salt4.78439212
4MP0005085_abnormal_gallbladder_physiolo4.77124568
5MP0003195_calcinosis3.72427038
6MP0008875_abnormal_xenobiotic_pharmacok3.58833812
7MP0001666_abnormal_nutrient_absorption3.25595358
8MP0003252_abnormal_bile_duct3.00748817
9MP0005083_abnormal_biliary_tract2.88282072
10MP0002138_abnormal_hepatobiliary_system2.64632555
11MP0004782_abnormal_surfactant_physiolog2.63059943
12MP0003868_abnormal_feces_composition2.61249380
13MP0010329_abnormal_lipoprotein_level2.46693510
14MP0009780_abnormal_chondrocyte_physiolo2.43465876
15MP0004019_abnormal_vitamin_homeostasis2.31541622
16MP0004043_abnormal_pH_regulation2.29400091
17MP0005332_abnormal_amino_acid2.21829006
18MP0003806_abnormal_nucleotide_metabolis2.21179912
19MP0003183_abnormal_peptide_metabolism2.16938876
20MP0000013_abnormal_adipose_tissue2.03554655
21MP0002909_abnormal_adrenal_gland1.92704392
22MP0002118_abnormal_lipid_homeostasis1.83905167
23MP0001944_abnormal_pancreas_morphology1.79905990
24MP0005379_endocrine/exocrine_gland_phen1.79482047
25MP0005220_abnormal_exocrine_pancreas1.75668635
26MP0004264_abnormal_extraembryonic_tissu1.72161765
27MP0009643_abnormal_urine_homeostasis1.71382705
28MP0005084_abnormal_gallbladder_morpholo1.61068888
29MP0000678_abnormal_parathyroid_gland1.60487409
30MP0002693_abnormal_pancreas_physiology1.55101280
31MP0005645_abnormal_hypothalamus_physiol1.54379402
32MP0005646_abnormal_pituitary_gland1.54281614
33MP0004147_increased_porphyrin_level1.54087389
34MP0003890_abnormal_embryonic-extraembry1.52248651
35MP0002160_abnormal_reproductive_system1.51282165
36MP0009840_abnormal_foam_cell1.48995216
37MP0004215_abnormal_myocardial_fiber1.48497632
38MP0002078_abnormal_glucose_homeostasis1.48431855
39MP0010386_abnormal_urinary_bladder1.44815023
40MP0004145_abnormal_muscle_electrophysio1.43954434
41MP0002837_dystrophic_cardiac_calcinosis1.40679229
42MP0001756_abnormal_urination1.38822937
43MP0000462_abnormal_digestive_system1.35592129
44MP0005410_abnormal_fertilization1.32543476
45MP0005636_abnormal_mineral_homeostasis1.31074470
46MP0000609_abnormal_liver_physiology1.30818419
47MP0002877_abnormal_melanocyte_morpholog1.28903552
48MP0008877_abnormal_DNA_methylation1.27673380
49MP0010368_abnormal_lymphatic_system1.26582344
50MP0001765_abnormal_ion_homeostasis1.25935520
51MP0003123_paternal_imprinting1.23288120
52MP0003191_abnormal_cellular_cholesterol1.19047113
53MP0002938_white_spotting1.17702807
54MP0006072_abnormal_retinal_apoptosis1.16250670
55MP0004084_abnormal_cardiac_muscle1.13587163
56MP0000003_abnormal_adipose_tissue1.13469330
57MP0003698_abnormal_male_reproductive1.10731122
58MP0005408_hypopigmentation1.09887739
59MP0003122_maternal_imprinting1.08608767
60MP0000749_muscle_degeneration1.07364568
61MP0001764_abnormal_homeostasis1.07318194
62MP0003879_abnormal_hair_cell1.05645142
63MP0008775_abnormal_heart_ventricle1.04939192
64MP0003283_abnormal_digestive_organ1.04740454
65MP0001299_abnormal_eye_distance/1.04309206
66MP0004085_abnormal_heartbeat1.03464526
67MP0003953_abnormal_hormone_level1.02814192
68MP0005319_abnormal_enzyme/_coenzyme1.02364049
69MP0003646_muscle_fatigue1.02329231
70MP0005058_abnormal_lysosome_morphology1.01986000
71MP0004885_abnormal_endolymph1.01758096
72MP0002234_abnormal_pharynx_morphology1.01506739
73MP0001664_abnormal_digestion1.01030002
74MP0000538_abnormal_urinary_bladder0.98863389
75MP0003937_abnormal_limbs/digits/tail_de0.98542767
76MP0001929_abnormal_gametogenesis0.98128747
77MP0001984_abnormal_olfaction0.97290170
78MP0008004_abnormal_stomach_pH0.94690200
79MP0002822_catalepsy0.93986755
80MP0000534_abnormal_ureter_morphology0.93892800
81MP0005535_abnormal_body_temperature0.93780174
82MP0003136_yellow_coat_color0.93711659
83MP0003119_abnormal_digestive_system0.93590838
84MP0002249_abnormal_larynx_morphology0.92775975
85MP0002102_abnormal_ear_morphology0.91427859
86MP0000230_abnormal_systemic_arterial0.90515178
87MP0001485_abnormal_pinna_reflex0.90059759
88MP0002876_abnormal_thyroid_physiology0.89618705
89MP0005584_abnormal_enzyme/coenzyme_acti0.89610834
90MP0000516_abnormal_urinary_system0.89395730
91MP0005367_renal/urinary_system_phenotyp0.89395730
92MP0008995_early_reproductive_senescence0.87996590
93MP0003950_abnormal_plasma_membrane0.87898342
94MP0005409_darkened_coat_color0.86224762
95MP0005448_abnormal_energy_balance0.85600544
96MP0000613_abnormal_salivary_gland0.84588980
97MP0006276_abnormal_autonomic_nervous0.83983115
98MP0000639_abnormal_adrenal_gland0.82819917
99MP0002638_abnormal_pupillary_reflex0.82267957
100MP0002210_abnormal_sex_determination0.81723067
101MP0005451_abnormal_body_composition0.81144535
102MP0005375_adipose_tissue_phenotype0.80872133
103MP0000653_abnormal_sex_gland0.80682613
104MP0003718_maternal_effect0.80033526
105MP0001188_hyperpigmentation0.79079149
106MP0009642_abnormal_blood_homeostasis0.78807949
107MP0002557_abnormal_social/conspecific_i0.78648972
108MP0002098_abnormal_vibrissa_morphology0.77432308
109MP0008872_abnormal_physiological_respon0.77161868
110MP0003315_abnormal_perineum_morphology0.76829087
111MP0002163_abnormal_gland_morphology0.76403001
112MP0005620_abnormal_muscle_contractility0.76215161
113MP0004133_heterotaxia0.76176777
114MP0010234_abnormal_vibrissa_follicle0.75934467
115MP0005334_abnormal_fat_pad0.75607099
116MP0000566_synostosis0.75439698
117MP0001502_abnormal_circadian_rhythm0.75362185
118MP0005253_abnormal_eye_physiology0.75345944
119MP0006036_abnormal_mitochondrial_physio0.75266204
120MP0008961_abnormal_basal_metabolism0.74488666
121MP0001145_abnormal_male_reproductive0.74440749
122MP0003942_abnormal_urinary_system0.74297348
123MP0005551_abnormal_eye_electrophysiolog0.73371730
124MP0005389_reproductive_system_phenotype0.72777816
125MP0003300_gastrointestinal_ulcer0.72338209
126MP0002896_abnormal_bone_mineralization0.72022508
127MP0005187_abnormal_penis_morphology0.71967257
128MP0002269_muscular_atrophy0.71435642
129MP0004272_abnormal_basement_membrane0.71298622
130MP0000383_abnormal_hair_follicle0.71148150
131MP0003959_abnormal_lean_body0.70546750
132MP0004130_abnormal_muscle_cell0.70366675
133MP0005670_abnormal_white_adipose0.69703248
134MP0005248_abnormal_Harderian_gland0.67949600
135MP0005666_abnormal_adipose_tissue0.67618919
136MP0000631_abnormal_neuroendocrine_gland0.66172811
137MP0002928_abnormal_bile_duct0.63816316
138MP0009697_abnormal_copulation0.63243041
139MP0002168_other_aberrant_phenotype0.61903667
140MP0001661_extended_life_span0.60756078
141MP0002136_abnormal_kidney_physiology0.57097656
142MP0001177_atelectasis0.56439228
143MP0002295_abnormal_pulmonary_circulatio0.56169159
144MP0000537_abnormal_urethra_morphology0.55505544
145MP0004270_analgesia0.47205358
146MP0000598_abnormal_liver_morphology0.45165606
147MP0003186_abnormal_redox_activity0.44843862
148MP0002069_abnormal_eating/drinking_beha0.44475529
149MP0005376_homeostasis/metabolism_phenot0.44391593
150MP0002971_abnormal_brown_adipose0.44213093
151MP0001879_abnormal_lymphatic_vessel0.43550018

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)5.70989039
2Hypoglycemic coma (HP:0001325)5.54446099
3Intrahepatic cholestasis (HP:0001406)4.81730541
4Hypoglycemic seizures (HP:0002173)4.75836399
5Hyperinsulinemic hypoglycemia (HP:0000825)4.73895385
6Gout (HP:0001997)4.37306588
7Ketoacidosis (HP:0001993)4.28851594
8Abnormality of monocarboxylic acid metabolism (HP:0010996)4.11635343
9Symptomatic seizures (HP:0011145)4.08273089
10Conjugated hyperbilirubinemia (HP:0002908)4.03846252
11Late onset (HP:0003584)3.85629880
12Hyperglycemia (HP:0003074)3.82229888
13Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.81033343
14Prolonged partial thromboplastin time (HP:0003645)3.78237285
15Ketosis (HP:0001946)3.77360244
16Deep venous thrombosis (HP:0002625)3.74368826
17Xanthomatosis (HP:0000991)3.69532970
18Tachypnea (HP:0002789)3.41312730
19Abnormality of the intrinsic pathway (HP:0010989)3.40187297
20Hypobetalipoproteinemia (HP:0003563)3.39542419
21Fat malabsorption (HP:0002630)3.33025420
22Hyperactive renin-angiotensin system (HP:0000841)3.25587370
23Abnormality of purine metabolism (HP:0004352)3.06988196
24Hyperglycinuria (HP:0003108)3.06745157
25Generalized aminoaciduria (HP:0002909)3.06642607
26Abnormality of glutamine family amino acid metabolism (HP:0010902)3.00207207
27Abnormality of endocrine pancreas physiology (HP:0012093)2.96486017
28Abnormality of the pancreatic islet cells (HP:0006476)2.96486017
29Hyperlipoproteinemia (HP:0010980)2.94658927
30Epidermoid cyst (HP:0200040)2.80603386
31Abnormality of the common coagulation pathway (HP:0010990)2.77193884
32Pancreatic islet-cell hyperplasia (HP:0004510)2.72165955
33Proximal tubulopathy (HP:0000114)2.71345511
34Glycosuria (HP:0003076)2.71143765
35Abnormality of urine glucose concentration (HP:0011016)2.71143765
36Abnormality of fatty-acid metabolism (HP:0004359)2.69167964
37Hyperglycinemia (HP:0002154)2.68972646
38Abnormality of calcium-phosphate metabolism (HP:0100530)2.68280218
39Joint hemorrhage (HP:0005261)2.66532406
40Pancreatic fibrosis (HP:0100732)2.63301667
41Abnormality of glycine metabolism (HP:0010895)2.62374623
42Abnormality of serine family amino acid metabolism (HP:0010894)2.62374623
43Hyperammonemia (HP:0001987)2.60957161
44Complement deficiency (HP:0004431)2.60389821
45Hydroxyprolinuria (HP:0003080)2.59764928
46Abnormality of proline metabolism (HP:0010907)2.59764928
47True hermaphroditism (HP:0010459)2.57834348
48Abnormality of renin-angiotensin system (HP:0000847)2.53894843
49Hyperphosphaturia (HP:0003109)2.53817386
50Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.52139350
51Hypolipoproteinemia (HP:0010981)2.49736572
52Abnormality of nucleobase metabolism (HP:0010932)2.44508922
53Interstitial pulmonary disease (HP:0006530)2.39170644
54Pancreatic cysts (HP:0001737)2.35821454
55Decreased circulating renin level (HP:0003351)2.33978548
56Abnormality of chloride homeostasis (HP:0011422)2.33632840
57Hyperuricemia (HP:0002149)2.33500656
58Increased purine levels (HP:0004368)2.33500656
59Abnormality of sulfur amino acid metabolism (HP:0004339)2.32700321
60Vascular calcification (HP:0004934)2.31482760
61Hypokalemia (HP:0002900)2.31199951
62Abnormality of magnesium homeostasis (HP:0004921)2.30406341
63Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.30270326
64Metabolic acidosis (HP:0001942)2.30138292
65Insulin-resistant diabetes mellitus (HP:0000831)2.28369236
66Abnormality of aspartate family amino acid metabolism (HP:0010899)2.28227560
67Hypotension (HP:0002615)2.28111445
68Hypomagnesemia (HP:0002917)2.27201790
69Alkalosis (HP:0001948)2.26708204
70Increased circulating renin level (HP:0000848)2.25240088
71Growth hormone excess (HP:0000845)2.24840381
72Abnormality of vitamin metabolism (HP:0100508)2.23428307
73Skin nodule (HP:0200036)2.22275092
74Abnormal pancreas size (HP:0012094)2.22202017
75Acanthocytosis (HP:0001927)2.21647826
76Hyperkalemia (HP:0002153)2.21490498
77Hepatocellular carcinoma (HP:0001402)2.20577108
78Retinal atrophy (HP:0001105)2.20460857
79Irritability (HP:0000737)2.19113690
80Congenital sensorineural hearing impairment (HP:0008527)2.18715853
81Hyperphosphatemia (HP:0002905)2.18323011
82Hypophosphatemia (HP:0002148)2.17794611
83Rimmed vacuoles (HP:0003805)2.16944227
84Type II lissencephaly (HP:0007260)2.14216963
85Insulin resistance (HP:0000855)2.13904862
86Dicarboxylic aciduria (HP:0003215)2.13900925
87Abnormality of dicarboxylic acid metabolism (HP:0010995)2.13900925
88Abnormal urine phosphate concentration (HP:0012599)2.13392973
89Intestinal atresia (HP:0011100)2.12600636
90Abnormality of potassium homeostasis (HP:0011042)2.12128841
91Abnormality of the renal cortex (HP:0011035)2.10783187
92Abnormal biliary tract morphology (HP:0012440)2.10511981
93Steatorrhea (HP:0002570)2.09774473
94Agitation (HP:0000713)2.08920000
95Osteomalacia (HP:0002749)2.08444954
96Molar tooth sign on MRI (HP:0002419)2.07834428
97Abnormality of midbrain morphology (HP:0002418)2.07834428
98Hyperparathyroidism (HP:0000843)2.06487027
99Double outlet right ventricle (HP:0001719)2.06246352
100Congenital malformation of the right heart (HP:0011723)2.06246352
101Hypoalphalipoproteinemia (HP:0003233)2.05857061
102Hyperbilirubinemia (HP:0002904)2.05396558
103Volvulus (HP:0002580)2.04294977
104Cystic liver disease (HP:0006706)2.04236234
105Malnutrition (HP:0004395)2.04158071
106Abnormality of vitamin B metabolism (HP:0004340)2.03721775
107Hyperaldosteronism (HP:0000859)2.02701445
108Medial flaring of the eyebrow (HP:0010747)2.02639795
109Delayed CNS myelination (HP:0002188)2.00732728
110Facial shape deformation (HP:0011334)1.99139999
111Potter facies (HP:0002009)1.99139999
112Protuberant abdomen (HP:0001538)1.99131431
113Hypothermia (HP:0002045)1.98577337
114Chronic hepatic failure (HP:0100626)1.98495727
115Abdominal distention (HP:0003270)1.98069337
116Cardiovascular calcification (HP:0011915)1.96355172
117Occipital encephalocele (HP:0002085)1.95563899
118Oligomenorrhea (HP:0000876)1.95437438
119Thyroid-stimulating hormone excess (HP:0002925)1.94679441
120Lethargy (HP:0001254)1.93643536
121Rickets (HP:0002748)1.93592269
122Renal salt wasting (HP:0000127)1.92393669
123Enlarged kidneys (HP:0000105)1.92154012
124Abnormality of the aortic arch (HP:0012303)1.91696998
125Hypokalemic alkalosis (HP:0001949)1.90906626
126Renal cortical cysts (HP:0000803)1.90045604
127Papillary thyroid carcinoma (HP:0002895)1.89920559
128Tubulointerstitial nephritis (HP:0001970)1.88669892
129Aplasia/Hypoplasia of the tongue (HP:0010295)1.87862690
130Large for gestational age (HP:0001520)1.87161484
131Chronic bronchitis (HP:0004469)1.86951086
132Pancreatitis (HP:0001733)1.86859801
133Abnormality of the renal medulla (HP:0100957)1.86670064
134Nephrolithiasis (HP:0000787)1.86667983
135Right ventricular cardiomyopathy (HP:0011663)1.86297599
136Dynein arm defect of respiratory motile cilia (HP:0012255)1.86188850
137Absent/shortened dynein arms (HP:0200106)1.86188850
138Male pseudohermaphroditism (HP:0000037)1.85572793
139Biliary tract neoplasm (HP:0100574)1.84199458
140Nephronophthisis (HP:0000090)1.80301328
141Optic nerve hypoplasia (HP:0000609)1.79409391
142Genital tract atresia (HP:0001827)1.78885014
143Gait imbalance (HP:0002141)1.78798357
144Sclerocornea (HP:0000647)1.78027965
145Congenital primary aphakia (HP:0007707)1.75999189
146Tubular atrophy (HP:0000092)1.75852416
147Abnormal ciliary motility (HP:0012262)1.74133652
148Abnormal respiratory motile cilium morphology (HP:0005938)1.73788705
149Abnormal respiratory epithelium morphology (HP:0012253)1.73788705
150Goiter (HP:0000853)1.73090786
151Hyperthyroidism (HP:0000836)1.72945304
152Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.72124441
153Pigmentary retinal degeneration (HP:0001146)1.71693813
154Abnormality of renal excretion (HP:0011036)1.68003218
155Thyroid carcinoma (HP:0002890)1.67985063
156Abnormality of the nasal septum (HP:0000419)1.67853820
157Calf muscle hypertrophy (HP:0008981)1.67275659
158Vaginal atresia (HP:0000148)1.67268334
159Hyperventilation (HP:0002883)1.66022005
160Abnormal urine output (HP:0012590)1.64055283
161Azoospermia (HP:0000027)1.63385384
162Exercise-induced myalgia (HP:0003738)1.63303198
163Abnormality of the vitamin B12 metabolism (HP:0004341)1.63185932
164Bundle branch block (HP:0011710)1.63057396
165Abnormal respiratory motile cilium physiology (HP:0012261)1.62727013
166Adrenal hypoplasia (HP:0000835)1.60965086

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR5.66491215
2MAPK155.38056256
3FRK4.51105699
4WNK34.38755428
5TAOK33.05370448
6PNCK2.94957898
7WNK42.71961968
8TNIK2.67968273
9BCKDK2.47398795
10PHKG12.13359624
11PHKG22.13359624
12CASK2.09890773
13EPHA22.07512910
14MAP3K22.01074657
15TRIB31.95923149
16OBSCN1.95451874
17FGFR41.90898165
18STK31.76978215
19MAP3K41.73082029
20ACVR1B1.70822545
21MAP3K121.64137862
22MUSK1.63877759
23AKT31.62041909
24MAP2K21.59559868
25HIPK21.58056941
26NTRK31.55848662
27PIK3CG1.50963071
28ERN11.47547029
29TIE11.46614554
30EPHA31.43609768
31MAP2K71.41264220
32PTK61.40028930
33MST1R1.33255575
34DAPK21.31559672
35FER1.30985722
36PASK1.29346363
37EPHB11.22812813
38CAMK1G1.18616622
39ADRBK21.16574293
40FGFR21.14853714
41BRSK21.14074162
42PINK11.11548228
43FLT31.09964992
44IRAK31.08479436
45MAP3K11.07225608
46IRAK11.06069946
47NME11.05813907
48EPHB21.05477016
49PLK41.03578279
50RIPK11.03207605
51NEK21.01519726
52MAP3K31.00549233
53PAK30.99766317
54SIK10.99446798
55STK380.93259152
56ERBB20.92208190
57PTK20.88914141
58UHMK10.88243690
59CSNK1G10.87856959
60MARK10.87796858
61GSK3A0.85749123
62STK390.85727609
63DYRK1B0.84459497
64LATS10.83478666
65GRK10.82648132
66DMPK0.82386721
67STK240.82086196
68BMPR1B0.81910535
69CSNK1G30.81906130
70LMTK20.81843121
71EPHA40.80897155
72SGK2230.79919002
73SGK4940.79919002
74PIK3CA0.78121778
75MET0.77851014
76PKN20.77782957
77WEE10.76476075
78CSNK1G20.76461726
79ERBB40.75426762
80MAP2K40.74971904
81PRKD30.73514055
82STK160.72973556
83NLK0.72585443
84ERBB30.71501128
85CAMK2D0.70225903
86BCR0.69743121
87ROCK10.69143335
88RET0.68811387
89NTRK10.67605475
90CAMK2G0.67420474
91OXSR10.66017870
92PLK20.65074285
93PRKCG0.64286824
94CSNK1A1L0.64028886
95PTK2B0.63917736
96WNK10.62966680
97MAP4K20.57972269
98MINK10.57441327
99MAP2K60.56083665
100MAP2K10.55307413
101DYRK20.53321672
102IRAK20.53014961
103PRKCE0.52010924
104PDGFRA0.51215192
105MKNK20.50953009
106PRKAA10.50820578
107FGFR30.50314568
108MAP3K50.50107071
109STK38L0.50095074
110PRKG10.47883258
111CAMK2B0.47406904
112PRKAA20.44731684
113MAP2K30.44430057
114CDC42BPA0.43525730
115SGK20.42785831
116ZAP700.42503206
117PRKD10.41874735
118PRKACG0.41677603
119ZAK0.41452554
120CSNK1E0.40945753
121PRKG20.39646401
122PLK30.37159589
123KSR10.36205928
124ADRBK10.35759991
125SGK10.35755369
126TRPM70.35720438
127PRKACB0.34286712
128PRKACA0.34167242
129DYRK30.33600854
130NUAK10.33171911
131RPS6KA20.32929897
132MST40.32572109
133PRKCH0.32083037
134PDGFRB0.32043870
135MAP3K110.31317266
136MAP3K60.30690272
137MAPK110.30627864
138PRKCZ0.30349445
139PDPK10.30236379
140CSNK1A10.30149230
141MYLK0.29651021
142PRKD20.28964923
143SGK30.28269116

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.69388033
2Sulfur metabolism_Homo sapiens_hsa009203.31907818
3Primary bile acid biosynthesis_Homo sapiens_hsa001202.80784729
4Tryptophan metabolism_Homo sapiens_hsa003802.69798164
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.45575957
6Nitrogen metabolism_Homo sapiens_hsa009102.35236175
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.32043198
8Butanoate metabolism_Homo sapiens_hsa006502.21867816
9Fatty acid degradation_Homo sapiens_hsa000712.18758163
10Fat digestion and absorption_Homo sapiens_hsa049752.05083859
11Histidine metabolism_Homo sapiens_hsa003402.03870226
12Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.87015184
13Arginine biosynthesis_Homo sapiens_hsa002201.86234530
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.84310626
15Propanoate metabolism_Homo sapiens_hsa006401.82807976
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.78543012
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.78422450
18Selenocompound metabolism_Homo sapiens_hsa004501.77173490
19Peroxisome_Homo sapiens_hsa041461.76153683
20Protein export_Homo sapiens_hsa030601.74112141
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.70056859
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.67271793
23Folate biosynthesis_Homo sapiens_hsa007901.57541526
24Complement and coagulation cascades_Homo sapiens_hsa046101.57535451
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.54222261
26PPAR signaling pathway_Homo sapiens_hsa033201.51556590
27Caffeine metabolism_Homo sapiens_hsa002321.50426408
28ABC transporters_Homo sapiens_hsa020101.50131135
29Bile secretion_Homo sapiens_hsa049761.47595052
30Fatty acid metabolism_Homo sapiens_hsa012121.46498397
31Starch and sucrose metabolism_Homo sapiens_hsa005001.42768306
32Phenylalanine metabolism_Homo sapiens_hsa003601.42623745
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.37084560
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.34610172
35beta-Alanine metabolism_Homo sapiens_hsa004101.33398507
36Pyruvate metabolism_Homo sapiens_hsa006201.30748699
37Fatty acid elongation_Homo sapiens_hsa000621.30087503
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.29868342
39Tyrosine metabolism_Homo sapiens_hsa003501.29344265
40Chemical carcinogenesis_Homo sapiens_hsa052041.26263176
41Fatty acid biosynthesis_Homo sapiens_hsa000611.21269869
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.20609711
43Drug metabolism - other enzymes_Homo sapiens_hsa009831.18842764
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18614451
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.18222634
46Insulin secretion_Homo sapiens_hsa049111.17949394
47Retinol metabolism_Homo sapiens_hsa008301.05421152
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04091632
49Arginine and proline metabolism_Homo sapiens_hsa003301.03607269
50Linoleic acid metabolism_Homo sapiens_hsa005911.01157357
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.00298714
52Steroid biosynthesis_Homo sapiens_hsa001000.98942369
53Vitamin digestion and absorption_Homo sapiens_hsa049770.94364164
54Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.93443436
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.93384302
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92470704
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.89515185
58Phototransduction_Homo sapiens_hsa047440.87754529
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82969480
60Glycerolipid metabolism_Homo sapiens_hsa005610.82667683
61Vitamin B6 metabolism_Homo sapiens_hsa007500.80612948
62Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80435038
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.79954832
64Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.79516237
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.79439323
66Galactose metabolism_Homo sapiens_hsa000520.76246459
67Carbon metabolism_Homo sapiens_hsa012000.73996373
68Glutathione metabolism_Homo sapiens_hsa004800.71661942
69Tight junction_Homo sapiens_hsa045300.71648176
70Circadian rhythm_Homo sapiens_hsa047100.70006136
71Hedgehog signaling pathway_Homo sapiens_hsa043400.67939946
72Vibrio cholerae infection_Homo sapiens_hsa051100.67302572
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66731305
742-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.65912743
75Lysine degradation_Homo sapiens_hsa003100.62755959
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.60023804
77Cardiac muscle contraction_Homo sapiens_hsa042600.59993627
78Serotonergic synapse_Homo sapiens_hsa047260.59695379
79TGF-beta signaling pathway_Homo sapiens_hsa043500.58338779
80Dopaminergic synapse_Homo sapiens_hsa047280.57251115
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57090944
82Mineral absorption_Homo sapiens_hsa049780.56156071
83Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55904062
84Sulfur relay system_Homo sapiens_hsa041220.55046411
85Hippo signaling pathway_Homo sapiens_hsa043900.54768339
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.54718705
87Dilated cardiomyopathy_Homo sapiens_hsa054140.54349985
88Oxidative phosphorylation_Homo sapiens_hsa001900.53996850
89Cocaine addiction_Homo sapiens_hsa050300.53231837
90Metabolic pathways_Homo sapiens_hsa011000.53120749
91Glucagon signaling pathway_Homo sapiens_hsa049220.52402302
92Ether lipid metabolism_Homo sapiens_hsa005650.51337329
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51275240
94Insulin resistance_Homo sapiens_hsa049310.49986562
95Thyroid hormone synthesis_Homo sapiens_hsa049180.49168076
96Renin secretion_Homo sapiens_hsa049240.48504697
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48197006
98Dorso-ventral axis formation_Homo sapiens_hsa043200.46622278
99Protein digestion and absorption_Homo sapiens_hsa049740.46295078
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45380528
101Type II diabetes mellitus_Homo sapiens_hsa049300.44868458
102Gap junction_Homo sapiens_hsa045400.44710577
103Pancreatic secretion_Homo sapiens_hsa049720.44595180
104Adherens junction_Homo sapiens_hsa045200.43894353
105Prion diseases_Homo sapiens_hsa050200.43798382
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.43224067
107Fructose and mannose metabolism_Homo sapiens_hsa000510.41888086
108Long-term depression_Homo sapiens_hsa047300.40549285
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.37742266
110Arachidonic acid metabolism_Homo sapiens_hsa005900.37474866
111Lysosome_Homo sapiens_hsa041420.37390865
112Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36042422
113Parkinsons disease_Homo sapiens_hsa050120.35922048
114Regulation of autophagy_Homo sapiens_hsa041400.35161437
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.35137639
116Staphylococcus aureus infection_Homo sapiens_hsa051500.33266054
117Renin-angiotensin system_Homo sapiens_hsa046140.31912534
118Sphingolipid metabolism_Homo sapiens_hsa006000.31495111
119Biosynthesis of amino acids_Homo sapiens_hsa012300.30701086
120Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29819257
121Alzheimers disease_Homo sapiens_hsa050100.28669988
122AMPK signaling pathway_Homo sapiens_hsa041520.28066813
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.21648808
124Adipocytokine signaling pathway_Homo sapiens_hsa049200.21637186
125Ovarian steroidogenesis_Homo sapiens_hsa049130.20975613

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