BARHL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.70441037
2presynaptic membrane organization (GO:0097090)5.32754054
3pyrimidine nucleobase catabolic process (GO:0006208)5.17015183
4neurofilament cytoskeleton organization (GO:0060052)4.80743309
5positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.78095837
6behavioral response to nicotine (GO:0035095)4.64880872
7polyketide metabolic process (GO:0030638)4.64297355
8doxorubicin metabolic process (GO:0044598)4.64297355
9daunorubicin metabolic process (GO:0044597)4.64297355
10vocalization behavior (GO:0071625)4.50594862
11postsynaptic membrane organization (GO:0001941)4.48693693
12presynaptic membrane assembly (GO:0097105)4.46445446
13regulation of synapse maturation (GO:0090128)4.45539662
14substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.39775493
15substrate-independent telencephalic tangential migration (GO:0021826)4.39775493
16establishment of mitochondrion localization (GO:0051654)4.39550431
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.38792085
18mitochondrion transport along microtubule (GO:0047497)4.33235849
19establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.33235849
20cerebellar Purkinje cell differentiation (GO:0021702)4.27943307
21adult walking behavior (GO:0007628)4.16116258
22transmission of nerve impulse (GO:0019226)4.11931442
23exploration behavior (GO:0035640)4.10318914
24midbrain development (GO:0030901)4.08811475
25neurotransmitter-gated ion channel clustering (GO:0072578)4.06703094
26G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.05852151
27synaptic vesicle maturation (GO:0016188)4.00771656
28cerebellar granule cell differentiation (GO:0021707)3.96661308
29neuron cell-cell adhesion (GO:0007158)3.93534822
30negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.92816528
31positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.84633656
32protein localization to synapse (GO:0035418)3.81914176
33membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.77490303
34striatum development (GO:0021756)3.69462543
35dendritic spine morphogenesis (GO:0060997)3.69118737
36layer formation in cerebral cortex (GO:0021819)3.66123108
37regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.62546205
38positive regulation of dendritic spine morphogenesis (GO:0061003)3.60361929
39forebrain neuron differentiation (GO:0021879)3.57931695
40regulation of synapse structural plasticity (GO:0051823)3.56843068
41cerebellum development (GO:0021549)3.55113016
42positive regulation of gastrulation (GO:2000543)3.50649429
43glutamate secretion (GO:0014047)3.50417120
44glutamate receptor signaling pathway (GO:0007215)3.43729609
45cell differentiation in hindbrain (GO:0021533)3.43662482
46axon ensheathment in central nervous system (GO:0032291)3.43170087
47central nervous system myelination (GO:0022010)3.43170087
48axon extension (GO:0048675)3.43014173
49short-term memory (GO:0007614)3.42750580
50positive regulation of synapse maturation (GO:0090129)3.39896350
51nucleobase catabolic process (GO:0046113)3.39090479
52paraxial mesoderm development (GO:0048339)3.37143481
53central nervous system projection neuron axonogenesis (GO:0021952)3.34310025
54positive regulation of synapse assembly (GO:0051965)3.33870982
55regulation of mesenchymal cell apoptotic process (GO:2001053)3.30350393
56adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.27744510
57negative regulation of synaptic transmission, GABAergic (GO:0032229)3.26225526
58spinal cord association neuron differentiation (GO:0021527)3.24643846
59prostate gland growth (GO:0060736)3.21342833
60cerebral cortex radially oriented cell migration (GO:0021799)3.21331927
61detection of molecule of bacterial origin (GO:0032490)3.20264217
62regulation of short-term neuronal synaptic plasticity (GO:0048172)3.19663426
63positive regulation of dendritic spine development (GO:0060999)3.19149707
64limb bud formation (GO:0060174)3.18641480
65ionotropic glutamate receptor signaling pathway (GO:0035235)3.17014544
66chaperone-mediated protein transport (GO:0072321)3.16348417
67response to histamine (GO:0034776)3.15438498
68atrial cardiac muscle cell action potential (GO:0086014)3.14879588
69regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.10332535
70regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.10332535
71positive regulation of neurotransmitter transport (GO:0051590)3.10213939
72behavioral response to cocaine (GO:0048148)3.09963680
73regulation of microtubule-based movement (GO:0060632)3.09884396
74retinal ganglion cell axon guidance (GO:0031290)3.08872973
75response to auditory stimulus (GO:0010996)3.06801600
76synaptic transmission, glutamatergic (GO:0035249)3.06657077
77hindbrain development (GO:0030902)3.06074451
78synaptic transmission, dopaminergic (GO:0001963)3.05758580
79dentate gyrus development (GO:0021542)3.05337962
80cellular anion homeostasis (GO:0030002)3.05086819
81dendrite morphogenesis (GO:0048813)3.04466051
82axonal fasciculation (GO:0007413)3.03595813
83dendritic spine organization (GO:0097061)3.03374762
84regulation of timing of cell differentiation (GO:0048505)3.03330140
85neurotransmitter secretion (GO:0007269)3.02390984
86regulation of respiratory system process (GO:0044065)3.01519920
87auditory receptor cell stereocilium organization (GO:0060088)3.00687112
88nonmotile primary cilium assembly (GO:0035058)3.00099887
89cellular potassium ion homeostasis (GO:0030007)2.99281303
90cell proliferation involved in metanephros development (GO:0072203)2.98207367
91regulation of postsynaptic membrane potential (GO:0060078)2.98024093
92cell migration in hindbrain (GO:0021535)2.97857428
93regulation of synaptic vesicle exocytosis (GO:2000300)2.97284462
94membrane hyperpolarization (GO:0060081)2.97118821
95negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.96991461
96establishment of planar polarity (GO:0001736)2.96589938
97establishment of tissue polarity (GO:0007164)2.96589938
98regulation of glutamate receptor signaling pathway (GO:1900449)2.96191773
99neuron projection extension (GO:1990138)2.95827481
100neuronal action potential propagation (GO:0019227)2.95632855
101behavioral fear response (GO:0001662)2.93555739
102behavioral defense response (GO:0002209)2.93555739
103synaptic vesicle endocytosis (GO:0048488)2.91862577
104central nervous system neuron differentiation (GO:0021953)2.91188419
105neuron maturation (GO:0042551)2.88036565
106astrocyte differentiation (GO:0048708)2.87222817
107hippocampus development (GO:0021766)2.87088307
108locomotory exploration behavior (GO:0035641)2.85922341
109synapse organization (GO:0050808)2.84744449
110gamma-aminobutyric acid signaling pathway (GO:0007214)2.82992367
111left/right axis specification (GO:0070986)2.82450352
112fear response (GO:0042596)2.82101091
113inner ear receptor stereocilium organization (GO:0060122)2.79805498
114regulation of excitatory postsynaptic membrane potential (GO:0060079)2.79324648
115regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.79212390
116developmental pigmentation (GO:0048066)2.79067994
117dopamine receptor signaling pathway (GO:0007212)2.78401672
118behavioral response to ethanol (GO:0048149)2.77988769
119synapse assembly (GO:0007416)2.77810544
120neuronal ion channel clustering (GO:0045161)2.76400323
121auditory behavior (GO:0031223)2.75992067
122olfactory bulb development (GO:0021772)2.75571589
123calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.75127097
124spinal cord development (GO:0021510)2.74541556
125regulation of dopamine secretion (GO:0014059)2.73845814
126regulation of male gonad development (GO:2000018)2.73773187
127regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.73431463
128regulation of development, heterochronic (GO:0040034)2.72684744
129cell differentiation in spinal cord (GO:0021515)2.72480789
130regulation of voltage-gated calcium channel activity (GO:1901385)2.72225605
131positive regulation of cellular amide metabolic process (GO:0034250)2.72181061
132positive regulation of membrane potential (GO:0045838)2.71804786
133positive regulation of synaptic transmission, GABAergic (GO:0032230)2.71715956
134urogenital system development (GO:0001655)2.71510967
135regulation of synaptic transmission, glutamatergic (GO:0051966)2.70888965
136positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.70464527
137positive regulation of mast cell activation involved in immune response (GO:0033008)2.70259361
138positive regulation of mast cell degranulation (GO:0043306)2.70259361
139dendrite development (GO:0016358)2.68972647
140mating behavior (GO:0007617)2.68450865
141aminoglycoside antibiotic metabolic process (GO:0030647)2.63761352
142synaptic vesicle docking involved in exocytosis (GO:0016081)2.61651010
143male sex determination (GO:0030238)2.60035827
144neuron recognition (GO:0008038)2.59889605
145regulation of synapse assembly (GO:0051963)2.58572379
146synaptic vesicle exocytosis (GO:0016079)2.58115086
147retina layer formation (GO:0010842)2.57438113
148neuron remodeling (GO:0016322)2.56534002
149regulation of synaptic vesicle transport (GO:1902803)2.55483635
150neuron-neuron synaptic transmission (GO:0007270)2.55027087
151positive regulation of neurotransmitter secretion (GO:0001956)2.54466156
152regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.53766089
153mechanosensory behavior (GO:0007638)2.53303124
154regulation of respiratory gaseous exchange (GO:0043576)2.53241192
155central nervous system neuron axonogenesis (GO:0021955)2.53121473
156negative regulation of myoblast differentiation (GO:0045662)2.51460892
157positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.51319359

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.63040625
2GBX2_23144817_ChIP-Seq_PC3_Human3.76531784
3EED_16625203_ChIP-ChIP_MESCs_Mouse3.23188686
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.01859838
5* EZH2_27304074_Chip-Seq_ESCs_Mouse2.99547888
6CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.95994607
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.95463572
8* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92932276
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.74121447
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.70431839
11* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.70431839
12* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.70323728
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66167524
14* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.65397442
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.62029702
16* CBX2_27304074_Chip-Seq_ESCs_Mouse2.54957842
17* RNF2_27304074_Chip-Seq_ESCs_Mouse2.54288122
18PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.47714342
19* EZH2_27294783_Chip-Seq_ESCs_Mouse2.43889803
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34484657
21* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32692370
22RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.26454925
23* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.25668390
24RBPJ_22232070_ChIP-Seq_NCS_Mouse2.21657189
25* RNF2_27304074_Chip-Seq_NSC_Mouse2.13812241
26* REST_21632747_ChIP-Seq_MESCs_Mouse2.10685856
27SMAD_19615063_ChIP-ChIP_OVARY_Human2.02550159
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.99790383
29* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.94288770
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.91609909
31* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.87151381
32IGF1R_20145208_ChIP-Seq_DFB_Human1.86967205
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.76908510
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.76213664
35DROSHA_22980978_ChIP-Seq_HELA_Human1.73519403
36POU5F1_16153702_ChIP-ChIP_HESCs_Human1.72950783
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72893828
38RARB_27405468_Chip-Seq_BRAIN_Mouse1.71460266
39* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.67782119
40* ERG_21242973_ChIP-ChIP_JURKAT_Human1.67710956
41CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66839733
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.60456606
43TP63_19390658_ChIP-ChIP_HaCaT_Human1.60181863
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58461667
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.58049710
46* P300_19829295_ChIP-Seq_ESCs_Human1.53044979
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52407559
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52330456
49POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49690539
50GATA1_26923725_Chip-Seq_HPCs_Mouse1.46334230
51* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44939947
52* RING1B_27294783_Chip-Seq_NPCs_Mouse1.43752351
53* RING1B_27294783_Chip-Seq_ESCs_Mouse1.41443970
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.38908626
55VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38157611
56SMAD4_21799915_ChIP-Seq_A2780_Human1.37305201
57* TP53_20018659_ChIP-ChIP_R1E_Mouse1.36178057
58AR_21572438_ChIP-Seq_LNCaP_Human1.34321105
59NANOG_18555785_Chip-Seq_ESCs_Mouse1.34184812
60MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33381500
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30944995
62TAF15_26573619_Chip-Seq_HEK293_Human1.23251844
63SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22964573
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22370132
65* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.21692818
66AR_25329375_ChIP-Seq_VCAP_Human1.20565293
67POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19651671
68TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19651671
69SUZ12_18555785_Chip-Seq_ESCs_Mouse1.19104612
70E2F1_18555785_Chip-Seq_ESCs_Mouse1.18957184
71* KDM2B_26808549_Chip-Seq_K562_Human1.17769116
72* CTCF_27219007_Chip-Seq_Bcells_Human1.17525352
73CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.16498216
74EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.16472063
75VDR_22108803_ChIP-Seq_LS180_Human1.16208049
76* RUNX2_22187159_ChIP-Seq_PCA_Human1.16165045
77PIAS1_25552417_ChIP-Seq_VCAP_Human1.15440550
78SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14690801
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14325760
80CMYC_18555785_Chip-Seq_ESCs_Mouse1.13590109
81DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13384211
82P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12924309
83ZFP281_18757296_ChIP-ChIP_E14_Mouse1.12728482
84P53_22387025_ChIP-Seq_ESCs_Mouse1.12518924
85PCGF2_27294783_Chip-Seq_ESCs_Mouse1.12254152
86CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11281248
87SMAD3_21741376_ChIP-Seq_EPCs_Human1.11262275
88YAP1_20516196_ChIP-Seq_MESCs_Mouse1.10388119
89FLI1_27457419_Chip-Seq_LIVER_Mouse1.08897749
90EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08655417
91MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.07761057
92STAT3_18555785_Chip-Seq_ESCs_Mouse1.07073654
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06248427
94IRF1_19129219_ChIP-ChIP_H3396_Human1.04679123
95MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04324753
96STAT3_23295773_ChIP-Seq_U87_Human1.03956712
97SALL1_21062744_ChIP-ChIP_HESCs_Human1.03858913
98ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03849661
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03803006
100NMYC_18555785_Chip-Seq_ESCs_Mouse1.03685807
101EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02769110
102* AR_19668381_ChIP-Seq_PC3_Human1.01702215
103EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.01174695
104* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00358281
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99881658
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99846993
107FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98335473
108BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.98258755
109P300_18555785_Chip-Seq_ESCs_Mouse0.97864746
110TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97124883
111* TCF4_23295773_ChIP-Seq_U87_Human0.97048948
112EZH2_27294783_Chip-Seq_NPCs_Mouse0.95646308
113NFE2_27457419_Chip-Seq_LIVER_Mouse0.94413849
114* EWS_26573619_Chip-Seq_HEK293_Human0.93685706
115OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93461702
116SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.92201504
117ARNT_22903824_ChIP-Seq_MCF-7_Human0.91634442
118NR3C1_23031785_ChIP-Seq_PC12_Mouse0.88263184
119HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.87043552
120SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.86776192
121KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.85123405
122ETV2_25802403_ChIP-Seq_MESCs_Mouse0.84174717
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82808156
124* SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.81605818
125* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.80892899
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.79990681
127TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.76850218
128CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.76277730
129NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.75253615
130SOX9_26525672_Chip-Seq_HEART_Mouse0.75136812
131MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74853275
132ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.73999972
133MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.73637804
134REST_19997604_ChIP-ChIP_NEURONS_Mouse0.73086777
135FUS_26573619_Chip-Seq_HEK293_Human0.71942981
136DPY_21335234_ChIP-Seq_ESCs_Mouse0.71842102
137THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.71790849
138STAT3_18555785_ChIP-Seq_MESCs_Mouse0.71714171

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.98566240
2MP0005423_abnormal_somatic_nervous3.55188394
3MP0000566_synostosis3.47847025
4MP0002653_abnormal_ependyma_morphology3.29157398
5MP0006276_abnormal_autonomic_nervous3.26651256
6MP0003123_paternal_imprinting3.11973315
7MP0001188_hyperpigmentation2.87596104
8MP0005646_abnormal_pituitary_gland2.68030412
9MP0002822_catalepsy2.66441248
10MP0004859_abnormal_synaptic_plasticity2.50228724
11MP0002638_abnormal_pupillary_reflex2.49794385
12MP0006292_abnormal_olfactory_placode2.45080770
13MP0009046_muscle_twitch2.41664392
14MP0000778_abnormal_nervous_system2.34958769
15MP0002102_abnormal_ear_morphology2.13870260
16MP0005645_abnormal_hypothalamus_physiol2.13111140
17MP0008877_abnormal_DNA_methylation2.12788004
18MP0002938_white_spotting2.10064423
19MP0003635_abnormal_synaptic_transmissio2.09944883
20MP0002184_abnormal_innervation2.05546356
21MP0001486_abnormal_startle_reflex2.01706283
22MP0001984_abnormal_olfaction1.95065508
23MP0003121_genomic_imprinting1.95061815
24MP0002557_abnormal_social/conspecific_i1.94449525
25MP0002063_abnormal_learning/memory/cond1.88046991
26MP0001348_abnormal_lacrimal_gland1.85687316
27MP0005499_abnormal_olfactory_system1.84404095
28MP0005394_taste/olfaction_phenotype1.84404095
29MP0009745_abnormal_behavioral_response1.83670538
30MP0001502_abnormal_circadian_rhythm1.82508911
31MP0008789_abnormal_olfactory_epithelium1.82014680
32MP0004742_abnormal_vestibular_system1.81543178
33MP0001529_abnormal_vocalization1.76224406
34MP0001346_abnormal_lacrimal_gland1.76165724
35MP0009379_abnormal_foot_pigmentation1.75905581
36MP0010030_abnormal_orbit_morphology1.72717289
37MP0002572_abnormal_emotion/affect_behav1.72472920
38MP0003122_maternal_imprinting1.68074065
39MP0002067_abnormal_sensory_capabilities1.67641166
40MP0002064_seizures1.64817291
41MP0002163_abnormal_gland_morphology1.58943487
42MP0003283_abnormal_digestive_organ1.55142821
43MP0001968_abnormal_touch/_nociception1.54929998
44MP0002734_abnormal_mechanical_nocicepti1.51420530
45MP0000631_abnormal_neuroendocrine_gland1.50638087
46MP0002272_abnormal_nervous_system1.49470627
47MP0008569_lethality_at_weaning1.48351354
48MP0008995_early_reproductive_senescence1.45272143
49MP0001440_abnormal_grooming_behavior1.44591506
50MP0003879_abnormal_hair_cell1.41345289
51MP0004145_abnormal_muscle_electrophysio1.39912944
52MP0002736_abnormal_nociception_after1.38890270
53MP0003136_yellow_coat_color1.38867426
54MP0005409_darkened_coat_color1.38667653
55MP0002234_abnormal_pharynx_morphology1.37888819
56MP0002735_abnormal_chemical_nociception1.37297274
57MP0000026_abnormal_inner_ear1.33163800
58MP0005377_hearing/vestibular/ear_phenot1.31709381
59MP0003878_abnormal_ear_physiology1.31709381
60MP0002909_abnormal_adrenal_gland1.28917829
61MP0005171_absent_coat_pigmentation1.28187394
62MP0002876_abnormal_thyroid_physiology1.27866339
63MP0005187_abnormal_penis_morphology1.25411490
64MP0000955_abnormal_spinal_cord1.23473224
65MP0002751_abnormal_autonomic_nervous1.22718318
66MP0003890_abnormal_embryonic-extraembry1.22129487
67MP0000015_abnormal_ear_pigmentation1.21274023
68MP0009697_abnormal_copulation1.20596363
69* MP0002882_abnormal_neuron_morphology1.18930396
70MP0005386_behavior/neurological_phenoty1.14611380
71MP0004924_abnormal_behavior1.14611380
72MP0001501_abnormal_sleep_pattern1.09612735
73MP0001905_abnormal_dopamine_level1.09187680
74* MP0005551_abnormal_eye_electrophysiolog1.07805246
75MP0004811_abnormal_neuron_physiology1.07626102
76MP0004142_abnormal_muscle_tone1.06838744
77* MP0002752_abnormal_somatic_nervous1.06032264
78MP0002152_abnormal_brain_morphology1.04370155
79MP0004133_heterotaxia1.03815489
80MP0003787_abnormal_imprinting1.02224233
81MP0005379_endocrine/exocrine_gland_phen1.01207542
82MP0000538_abnormal_urinary_bladder1.00182015
83MP0003137_abnormal_impulse_conducting0.99657332
84MP0010386_abnormal_urinary_bladder0.97307797
85MP0006072_abnormal_retinal_apoptosis0.94356167
86MP0005174_abnormal_tail_pigmentation0.94317247
87MP0002229_neurodegeneration0.94239207
88MP0005253_abnormal_eye_physiology0.93100436
89MP0003938_abnormal_ear_development0.91778464
90MP0002928_abnormal_bile_duct0.91219896
91MP0001963_abnormal_hearing_physiology0.90341195
92MP0003119_abnormal_digestive_system0.89660506
93* MP0002066_abnormal_motor_capabilities/c0.89479806
94MP0002249_abnormal_larynx_morphology0.88457243
95MP0004782_abnormal_surfactant_physiolog0.87611600
96* MP0005195_abnormal_posterior_eye0.87402211
97MP0003861_abnormal_nervous_system0.87218022
98MP0001299_abnormal_eye_distance/0.86547005
99MP0001970_abnormal_pain_threshold0.86311089
100MP0003385_abnormal_body_wall0.84860586
101MP0003329_amyloid_beta_deposits0.84579191
102MP0000049_abnormal_middle_ear0.83607254
103MP0001485_abnormal_pinna_reflex0.83337782
104MP0005389_reproductive_system_phenotype0.83053757
105MP0004270_analgesia0.82514533
106MP0002160_abnormal_reproductive_system0.82257323
107MP0000569_abnormal_digit_pigmentation0.82024196
108MP0001919_abnormal_reproductive_system0.80046185
109MP0000678_abnormal_parathyroid_gland0.79228916
110MP0004885_abnormal_endolymph0.78594631
111MP0003942_abnormal_urinary_system0.78471298
112MP0009053_abnormal_anal_canal0.77943429
113MP0004858_abnormal_nervous_system0.77679990
114MP0005248_abnormal_Harderian_gland0.77202285
115MP0003315_abnormal_perineum_morphology0.76263881
116MP0005391_vision/eye_phenotype0.75419299
117MP0003183_abnormal_peptide_metabolism0.75054176
118MP0002733_abnormal_thermal_nociception0.74808365
119MP0000681_abnormal_thyroid_gland0.74520468
120MP0002116_abnormal_craniofacial_bone0.69646508
121MP0002069_abnormal_eating/drinking_beha0.68239135
122MP0002233_abnormal_nose_morphology0.68154663
123MP0001986_abnormal_taste_sensitivity0.66267723
124MP0003633_abnormal_nervous_system0.66196069
125MP0001293_anophthalmia0.65639796
126MP0002210_abnormal_sex_determination0.64862800
127MP0003698_abnormal_male_reproductive0.64813243

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.52211852
2Febrile seizures (HP:0002373)4.73616215
3Focal motor seizures (HP:0011153)4.30789319
4Abnormality of the corticospinal tract (HP:0002492)3.82753485
5Progressive cerebellar ataxia (HP:0002073)3.82627076
6Limb dystonia (HP:0002451)3.50343766
7True hermaphroditism (HP:0010459)3.39795123
8Polyphagia (HP:0002591)3.26873941
9Septo-optic dysplasia (HP:0100842)3.16203536
10Elfin facies (HP:0004428)3.09747097
11Hypoplasia of the fovea (HP:0007750)3.09378528
12Aplasia/Hypoplasia of the fovea (HP:0008060)3.09378528
13Narrow nasal bridge (HP:0000446)3.04703893
14Optic nerve hypoplasia (HP:0000609)3.04622980
15Drooling (HP:0002307)2.99502187
16Epileptic encephalopathy (HP:0200134)2.99038464
17Abnormal sex determination (HP:0012244)2.91956866
18Sex reversal (HP:0012245)2.91956866
19Hyperventilation (HP:0002883)2.89024980
20Abnormal pancreas size (HP:0012094)2.87892497
21Degeneration of the lateral corticospinal tracts (HP:0002314)2.79044509
22Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.79044509
23Supranuclear gaze palsy (HP:0000605)2.76500380
24Atonic seizures (HP:0010819)2.76097651
25Excessive salivation (HP:0003781)2.73830860
26Impaired vibration sensation in the lower limbs (HP:0002166)2.73248145
27Protruding tongue (HP:0010808)2.72551969
28Maternal diabetes (HP:0009800)2.72485246
29Anomalous pulmonary venous return (HP:0010772)2.65410331
30Abnormal number of incisors (HP:0011064)2.63643962
31Abnormal eating behavior (HP:0100738)2.61483993
32Focal seizures (HP:0007359)2.59978628
33Genetic anticipation (HP:0003743)2.59592533
34Dynein arm defect of respiratory motile cilia (HP:0012255)2.59010999
35Absent/shortened dynein arms (HP:0200106)2.59010999
36Severe visual impairment (HP:0001141)2.55898916
37Abnormality of the lower motor neuron (HP:0002366)2.54312742
38Rib fusion (HP:0000902)2.53020493
39Renovascular hypertension (HP:0100817)2.52852428
40Chromosomal breakage induced by crosslinking agents (HP:0003221)2.48765765
41Amblyopia (HP:0000646)2.47622271
42Medial flaring of the eyebrow (HP:0010747)2.45424700
43Nephrogenic diabetes insipidus (HP:0009806)2.45319356
44Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.42412880
45Obstructive sleep apnea (HP:0002870)2.41643517
46Action tremor (HP:0002345)2.38484629
47Abnormal ciliary motility (HP:0012262)2.37200750
48Generalized tonic-clonic seizures (HP:0002069)2.37062258
49Spastic gait (HP:0002064)2.36630490
50Aplasia/Hypoplasia of the lens (HP:0008063)2.35419134
51Gait imbalance (HP:0002141)2.35135383
52Gaze-evoked nystagmus (HP:0000640)2.34877543
53Poor suck (HP:0002033)2.32806771
54Abnormality of the fovea (HP:0000493)2.32764117
55Flat cornea (HP:0007720)2.29259686
56Morphological abnormality of the pyramidal tract (HP:0002062)2.29153653
57Aplasia/Hypoplasia of the macula (HP:0008059)2.28956642
58Amyotrophic lateral sclerosis (HP:0007354)2.27003420
59Double outlet right ventricle (HP:0001719)2.26122646
60Congenital malformation of the right heart (HP:0011723)2.26122646
61Hepatoblastoma (HP:0002884)2.25374282
62Pachygyria (HP:0001302)2.25140809
63Sleep apnea (HP:0010535)2.22094318
64Overriding aorta (HP:0002623)2.21815997
65Abnormality of the intervertebral disk (HP:0005108)2.21625255
66Pancreatic fibrosis (HP:0100732)2.20973753
67Congenital primary aphakia (HP:0007707)2.20272886
68Abnormality of the labia minora (HP:0012880)2.19739115
69Renal duplication (HP:0000075)2.18195227
70Lissencephaly (HP:0001339)2.17740048
71Fetal akinesia sequence (HP:0001989)2.16460681
72Growth hormone deficiency (HP:0000824)2.14797113
73Nephronophthisis (HP:0000090)2.14304945
74Urinary bladder sphincter dysfunction (HP:0002839)2.14088571
75Oligodactyly (hands) (HP:0001180)2.13645081
76Unilateral renal agenesis (HP:0000122)2.12857196
77Abnormality of the pulmonary veins (HP:0011718)2.12419916
78Supernumerary spleens (HP:0009799)2.10426519
79Status epilepticus (HP:0002133)2.10321871
80Abnormality of binocular vision (HP:0011514)2.09082484
81Diplopia (HP:0000651)2.09082484
82Concave nail (HP:0001598)2.08659107
83Torticollis (HP:0000473)2.08301282
84Vaginal atresia (HP:0000148)2.07766457
85Agitation (HP:0000713)2.06360377
86Hypoplasia of the brainstem (HP:0002365)2.05661956
87Aplasia/Hypoplasia of the brainstem (HP:0007362)2.05661956
88Ectopic kidney (HP:0000086)2.05627548
89Parakeratosis (HP:0001036)2.05460003
90Congenital sensorineural hearing impairment (HP:0008527)2.05428912
91Genital tract atresia (HP:0001827)2.04343235
92Urinary urgency (HP:0000012)2.02511819
93Absence seizures (HP:0002121)2.02443856
94Aplasia/Hypoplasia affecting the fundus (HP:0008057)2.01780372
95Hyperacusis (HP:0010780)2.01168193
96Abnormal respiratory motile cilium physiology (HP:0012261)2.00235218
97Decreased central vision (HP:0007663)1.99842726
98Hypothermia (HP:0002045)1.99325440
99Bony spicule pigmentary retinopathy (HP:0007737)1.98402364
100Postaxial foot polydactyly (HP:0001830)1.97059244
101Ankle clonus (HP:0011448)1.96769718
102Abnormality of the carotid arteries (HP:0005344)1.96456311
103Dialeptic seizures (HP:0011146)1.95225209
104Anophthalmia (HP:0000528)1.94396991
105Chronic hepatic failure (HP:0100626)1.94393785
106Abnormal respiratory motile cilium morphology (HP:0005938)1.93972660
107Abnormal respiratory epithelium morphology (HP:0012253)1.93972660
108Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93874501
109Broad-based gait (HP:0002136)1.93498223
110Abnormal rod and cone electroretinograms (HP:0008323)1.93405172
111Incomplete penetrance (HP:0003829)1.93200632
112Neonatal hypoglycemia (HP:0001998)1.92930170
113Abnormality of incisor morphology (HP:0011063)1.92695343
114Preaxial hand polydactyly (HP:0001177)1.92559454
115Poor coordination (HP:0002370)1.91975435
116Prolonged QT interval (HP:0001657)1.90078069
117Anterior segment dysgenesis (HP:0007700)1.89213078
118Congenital stationary night blindness (HP:0007642)1.88177291
119Spastic tetraplegia (HP:0002510)1.87889382
120Aplasia of the musculature (HP:0100854)1.87528515
121Increased corneal curvature (HP:0100692)1.87038797
122Keratoconus (HP:0000563)1.87038797
123Absent eyebrow (HP:0002223)1.86741809
124Optic neuritis (HP:0100653)1.86371020
125Retrobulbar optic neuritis (HP:0100654)1.86371020
126Abnormality of the incisor (HP:0000676)1.85497352
127Diastasis recti (HP:0001540)1.84678415
128Renal Fanconi syndrome (HP:0001994)1.84255940
129Neurofibrillary tangles (HP:0002185)1.82941522
130Insomnia (HP:0100785)1.82827460
131Depression (HP:0000716)1.82596440
132Visual hallucinations (HP:0002367)1.82170761
133Chromsome breakage (HP:0040012)1.81741314
134Spina bifida occulta (HP:0003298)1.80481637
135Myotonia (HP:0002486)1.79717514
136Specific learning disability (HP:0001328)1.79637548
137Abolished electroretinogram (ERG) (HP:0000550)1.79153953
138Absent septum pellucidum (HP:0001331)1.78109820
139Abnormality of midbrain morphology (HP:0002418)1.77874763
140Molar tooth sign on MRI (HP:0002419)1.77874763
141Aplasia/Hypoplasia affecting the retina (HP:0008061)1.76342014
142Pendular nystagmus (HP:0012043)1.75725641
143Anxiety (HP:0000739)1.75449768
144Focal dystonia (HP:0004373)1.75449099
145Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.75394170
146Postaxial hand polydactyly (HP:0001162)1.74404168
147Cerebral hypomyelination (HP:0006808)1.74057736
148Choroideremia (HP:0001139)1.72990701
149Abnormal social behavior (HP:0012433)1.72484548
150Impaired social interactions (HP:0000735)1.72484548
151Hemiparesis (HP:0001269)1.70090587
152Occipital encephalocele (HP:0002085)1.69939146
153Failure to thrive in infancy (HP:0001531)1.69237406
154Bradycardia (HP:0001662)1.68384016
155Abnormality of the septum pellucidum (HP:0007375)1.66942999
156Intellectual disability, moderate (HP:0002342)1.66821808
157Absent speech (HP:0001344)1.66677776
158Tented upper lip vermilion (HP:0010804)1.66563611
159Hypoplasia of the corpus callosum (HP:0002079)1.66097515
160Anencephaly (HP:0002323)1.65548456
161Cutaneous finger syndactyly (HP:0010554)1.65395520
162Abnormality of the diencephalon (HP:0010662)1.65392376
163Intention tremor (HP:0002080)1.64744339
164Restlessness (HP:0000711)1.64682549
165Increased hepatocellular lipid droplets (HP:0006565)1.64431080
166Abnormality of the renal medulla (HP:0100957)1.64316512
167Oligodactyly (HP:0012165)1.63428707
168Esotropia (HP:0000565)1.62854145
169Abnormality of the aortic arch (HP:0012303)1.62821436
170Abnormality of cells of the erythroid lineage (HP:0012130)1.62200130
171Epileptiform EEG discharges (HP:0011182)1.61424530
172Dysmetria (HP:0001310)1.60952448
173Abnormal drinking behavior (HP:0030082)1.59829361

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK35.07471531
2CASK4.28739832
3NTRK22.64457549
4LIMK12.63619929
5ERBB32.57564494
6MAP2K72.51558755
7MAP3K92.31671481
8CAMKK12.27457373
9MARK12.22325848
10EPHA32.21620699
11EPHB22.18787276
12AKT32.18200564
13TNIK2.16056042
14YES12.10752583
15DAPK22.08146928
16MAPK132.07647791
17INSRR2.07320177
18BRD41.96820942
19KSR11.89282905
20BCR1.80956831
21PRPF4B1.69944429
22CDC42BPA1.65101630
23SGK21.64474554
24IRAK21.64165988
25CDK81.55694510
26NEK61.54206345
27IRAK41.50555090
28SGK2231.47193910
29SGK4941.47193910
30SRPK11.47125457
31STK161.41560828
32MAP3K141.38539413
33BMPR21.35507011
34MAP3K111.33498932
35UHMK11.32478375
36MINK11.32434912
37PHKG11.31898064
38PHKG21.31898064
39FGFR21.31335192
40EPHA41.31233567
41SIK21.29284667
42DYRK1A1.28822486
43PNCK1.27105055
44MARK31.25914823
45MAP3K61.22276757
46NTRK31.21676010
47PAK31.20991385
48WNK41.20592835
49MAP3K121.08947369
50MAP3K41.07133299
51WNK31.06407049
52DYRK1B1.06222057
53GRK11.05986003
54DYRK21.05840165
55MARK21.01817442
56CAMK10.94853056
57CSNK1G20.94372018
58ADRBK20.93180944
59ERBB20.91942928
60WNK10.90180557
61TXK0.86918996
62STK240.86693893
63STK110.86153073
64PRKCG0.85625732
65NTRK10.82995775
66ICK0.82660901
67CDK190.81708074
68IRAK10.80039453
69CDK140.78429652
70BMPR1B0.77842287
71MKNK10.77313221
72CDK150.77214476
73PRKCH0.74050435
74STK38L0.73404873
75SGK30.71861706
76CDK11A0.71321165
77CAMK40.71154811
78CDK30.70764542
79MAPK150.69774297
80CHUK0.68267280
81PRKD30.67796331
82RPS6KA20.67717700
83FGFR30.65596455
84VRK10.65359355
85PAK60.64615500
86CSNK1E0.63900133
87PRKCE0.63542812
88CSNK1A1L0.61267311
89ROCK20.61245255
90CSNK1G30.60063649
91PLK20.59447853
92RPS6KA60.57209784
93PINK10.56407221
94RPS6KC10.55299061
95RPS6KL10.55299061
96PKN10.53999455
97IKBKE0.53864952
98OXSR10.53742720
99ROCK10.53314688
100BRAF0.50910704
101TAOK20.48883294
102RIPK40.48577157
103CDK50.48107622
104PRKACA0.47897671
105RPS6KB10.47640225
106PRKAA10.47479331
107CAMK1D0.47403541
108STK390.45922890
109RPS6KA30.44958851
110ZAK0.44695781
111BRSK10.44547348
112CCNB10.43324140
113SGK10.42701777
114CAMK2A0.41357015
115CSNK1G10.40663123
116PBK0.39714101
117TIE10.38430610
118MKNK20.37942612
119MAPK120.37894851
120CAMKK20.37590219
121PRKDC0.37122064
122ABL20.36710536
123TLK10.36522171
124TYRO30.36063614
125MAPK70.35963210
126PLK30.35377311
127PRKG10.34894560
128EIF2AK20.34789602
129SIK10.33347745
130HIPK20.32396873
131CDK180.32246553
132GSK3B0.32092030
133MAPK90.31744066
134PRKCZ0.31653255
135CSNK1A10.31508716
136PDK20.31401700
137IRAK30.31275632
138AURKA0.31180420
139DYRK30.30086671
140MAPK80.29984206
141MAP2K40.29865755
142MUSK0.29474149
143RPS6KA10.29229568
144AKT20.27949377
145CAMK1G0.27136740
146PRKCD0.25354899
147PRKCQ0.24807182
148PLK10.24769001
149MAPK140.24462225
150AKT10.24437195
151CDK20.24188079

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.37817452
2Oxidative phosphorylation_Homo sapiens_hsa001902.75221977
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.60238762
4Synaptic vesicle cycle_Homo sapiens_hsa047212.58798568
5Parkinsons disease_Homo sapiens_hsa050122.58128657
6Morphine addiction_Homo sapiens_hsa050322.25212897
7Glutamatergic synapse_Homo sapiens_hsa047242.23548951
8Circadian entrainment_Homo sapiens_hsa047132.18858769
9GABAergic synapse_Homo sapiens_hsa047272.12527800
10Basal cell carcinoma_Homo sapiens_hsa052172.11060143
11Axon guidance_Homo sapiens_hsa043602.06551975
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.01077281
13Taste transduction_Homo sapiens_hsa047421.92749700
14Alzheimers disease_Homo sapiens_hsa050101.89433708
15SNARE interactions in vesicular transport_Homo sapiens_hsa041301.85205199
16Serotonergic synapse_Homo sapiens_hsa047261.71595415
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69940861
18Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.66486579
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.64627354
20Long-term depression_Homo sapiens_hsa047301.62067242
21Huntingtons disease_Homo sapiens_hsa050161.62041414
22Ribosome_Homo sapiens_hsa030101.59963343
23Olfactory transduction_Homo sapiens_hsa047401.54596455
24Phototransduction_Homo sapiens_hsa047441.54514439
25Notch signaling pathway_Homo sapiens_hsa043301.51637923
26Insulin secretion_Homo sapiens_hsa049111.42716072
27Graft-versus-host disease_Homo sapiens_hsa053321.37826787
28Type II diabetes mellitus_Homo sapiens_hsa049301.36953203
29Circadian rhythm_Homo sapiens_hsa047101.34181257
30Dopaminergic synapse_Homo sapiens_hsa047281.31146852
31Cholinergic synapse_Homo sapiens_hsa047251.30112264
32Type I diabetes mellitus_Homo sapiens_hsa049401.27397289
33Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.27101296
34Hedgehog signaling pathway_Homo sapiens_hsa043401.22695664
35Melanogenesis_Homo sapiens_hsa049161.17425291
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.17243493
37Wnt signaling pathway_Homo sapiens_hsa043101.15854487
38Long-term potentiation_Homo sapiens_hsa047201.15845686
39Calcium signaling pathway_Homo sapiens_hsa040201.14743105
40Basal transcription factors_Homo sapiens_hsa030221.09814749
41Amphetamine addiction_Homo sapiens_hsa050311.08975755
42Alcoholism_Homo sapiens_hsa050341.08552533
43Salivary secretion_Homo sapiens_hsa049701.04589073
44Cocaine addiction_Homo sapiens_hsa050301.02802155
45Aldosterone synthesis and secretion_Homo sapiens_hsa049251.01241670
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.00622806
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.97463774
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.97261368
49Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93943000
50ErbB signaling pathway_Homo sapiens_hsa040120.93679947
51Toll-like receptor signaling pathway_Homo sapiens_hsa046200.92561091
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91587991
53Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89205705
54Allograft rejection_Homo sapiens_hsa053300.89000219
55cAMP signaling pathway_Homo sapiens_hsa040240.86424933
56Fanconi anemia pathway_Homo sapiens_hsa034600.83010265
57Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.82723891
58Rheumatoid arthritis_Homo sapiens_hsa053230.81625401
59Dilated cardiomyopathy_Homo sapiens_hsa054140.80999507
60Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.80489217
61Endometrial cancer_Homo sapiens_hsa052130.78584817
62Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.78332856
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78144929
64Regulation of autophagy_Homo sapiens_hsa041400.78000869
65Gap junction_Homo sapiens_hsa045400.76301661
66Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.75641245
67Vibrio cholerae infection_Homo sapiens_hsa051100.74837006
68Colorectal cancer_Homo sapiens_hsa052100.73993597
69Bile secretion_Homo sapiens_hsa049760.71897975
70Hippo signaling pathway_Homo sapiens_hsa043900.71355142
71Oxytocin signaling pathway_Homo sapiens_hsa049210.70813281
72Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70288758
73Oocyte meiosis_Homo sapiens_hsa041140.69917166
74African trypanosomiasis_Homo sapiens_hsa051430.69526202
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69367954
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68795476
77Phagosome_Homo sapiens_hsa041450.68356280
78Cardiac muscle contraction_Homo sapiens_hsa042600.66410454
79Estrogen signaling pathway_Homo sapiens_hsa049150.65524167
80Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63984708
81Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.63915982
82Pancreatic secretion_Homo sapiens_hsa049720.60994017
83cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60300011
84Gastric acid secretion_Homo sapiens_hsa049710.60178173
85Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60018832
86Renin secretion_Homo sapiens_hsa049240.59705292
87Melanoma_Homo sapiens_hsa052180.59174165
88Thyroid hormone synthesis_Homo sapiens_hsa049180.58613068
89Prolactin signaling pathway_Homo sapiens_hsa049170.58470129
90MAPK signaling pathway_Homo sapiens_hsa040100.57950187
91Rap1 signaling pathway_Homo sapiens_hsa040150.56990602
92Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56214245
93Chemokine signaling pathway_Homo sapiens_hsa040620.55560959
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54684021
95Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54664946
96Spliceosome_Homo sapiens_hsa030400.54340709
97Inositol phosphate metabolism_Homo sapiens_hsa005620.53396833
98Autoimmune thyroid disease_Homo sapiens_hsa053200.53293906
99Protein export_Homo sapiens_hsa030600.53210107
100Ovarian steroidogenesis_Homo sapiens_hsa049130.51040615
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49570527
102Salmonella infection_Homo sapiens_hsa051320.49380327
103Collecting duct acid secretion_Homo sapiens_hsa049660.47759413
104Glioma_Homo sapiens_hsa052140.46769034
105NF-kappa B signaling pathway_Homo sapiens_hsa040640.46498186
106Leishmaniasis_Homo sapiens_hsa051400.46083859
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.45961466
108Non-small cell lung cancer_Homo sapiens_hsa052230.44321618
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42485347
110Ras signaling pathway_Homo sapiens_hsa040140.42201774
111RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40854267
112GnRH signaling pathway_Homo sapiens_hsa049120.40829773
113Tuberculosis_Homo sapiens_hsa051520.40478803
114Vascular smooth muscle contraction_Homo sapiens_hsa042700.40334458
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39944662
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.39745730
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.39207877
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.38717244
119Prion diseases_Homo sapiens_hsa050200.38635163
120Measles_Homo sapiens_hsa051620.38412827
121Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37903884
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36919763
123FoxO signaling pathway_Homo sapiens_hsa040680.36791310
124TNF signaling pathway_Homo sapiens_hsa046680.35974088
125Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.35859412
126Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.34958021
127Steroid biosynthesis_Homo sapiens_hsa001000.34696573
128Glucagon signaling pathway_Homo sapiens_hsa049220.33865239
129VEGF signaling pathway_Homo sapiens_hsa043700.32631179
130Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.31833972
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31786225
132Arginine and proline metabolism_Homo sapiens_hsa003300.29800516
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.24266721
134Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.23546691
135Endocytosis_Homo sapiens_hsa041440.20926340
136RNA degradation_Homo sapiens_hsa030180.20447650
137Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.18734848

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