BANF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.27363550
2viral transcription (GO:0019083)5.62985190
3translational termination (GO:0006415)5.47694624
4ribosomal small subunit biogenesis (GO:0042274)5.42858190
5DNA deamination (GO:0045006)5.37997631
6maturation of SSU-rRNA (GO:0030490)5.26269288
7DNA strand elongation involved in DNA replication (GO:0006271)4.98169529
8telomere maintenance via semi-conservative replication (GO:0032201)4.92269120
9translational elongation (GO:0006414)4.90619035
10chaperone-mediated protein transport (GO:0072321)4.87168599
11SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.80896270
12establishment of protein localization to mitochondrial membrane (GO:0090151)4.79126349
13DNA strand elongation (GO:0022616)4.73932804
14cotranslational protein targeting to membrane (GO:0006613)4.70835263
15protein targeting to ER (GO:0045047)4.67724758
16respiratory electron transport chain (GO:0022904)4.58027480
17translational initiation (GO:0006413)4.53954256
18regulation of mitochondrial translation (GO:0070129)4.51607770
19electron transport chain (GO:0022900)4.47249152
20mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.43374317
21establishment of protein localization to endoplasmic reticulum (GO:0072599)4.42891112
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.42539715
23protein localization to endoplasmic reticulum (GO:0070972)4.41487130
24* establishment of integrated proviral latency (GO:0075713)4.39619991
25DNA replication initiation (GO:0006270)4.38683111
26ribosomal large subunit biogenesis (GO:0042273)4.37726253
27cellular protein complex disassembly (GO:0043624)4.33190926
28viral life cycle (GO:0019058)4.32806458
29telomere maintenance via recombination (GO:0000722)4.31260581
30formation of translation preinitiation complex (GO:0001731)4.27646528
31ribonucleoprotein complex biogenesis (GO:0022613)4.12624581
32proteasome assembly (GO:0043248)4.10170903
33mitotic recombination (GO:0006312)4.03274064
34DNA replication checkpoint (GO:0000076)3.94026740
35deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.92737982
36protein complex disassembly (GO:0043241)3.85857526
37DNA unwinding involved in DNA replication (GO:0006268)3.85574160
38CENP-A containing nucleosome assembly (GO:0034080)3.85517731
39translation (GO:0006412)3.84406945
40telomere maintenance via telomere lengthening (GO:0010833)3.84404121
41spliceosomal snRNP assembly (GO:0000387)3.81185058
42protein complex biogenesis (GO:0070271)3.80265501
43chromatin remodeling at centromere (GO:0031055)3.78516691
44nucleobase biosynthetic process (GO:0046112)3.75794719
45nucleotide-excision repair, DNA gap filling (GO:0006297)3.73240266
46* establishment of viral latency (GO:0019043)3.71448754
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.70055264
48rRNA processing (GO:0006364)3.69457599
49mitochondrial respiratory chain complex assembly (GO:0033108)3.66748239
50macromolecular complex disassembly (GO:0032984)3.66536300
51oxidative phosphorylation (GO:0006119)3.65974562
52pseudouridine synthesis (GO:0001522)3.65386350
53protein maturation by protein folding (GO:0022417)3.64688127
54protein targeting to mitochondrion (GO:0006626)3.61803316
55ribosome biogenesis (GO:0042254)3.59006930
56rRNA metabolic process (GO:0016072)3.55485494
57NADH dehydrogenase complex assembly (GO:0010257)3.54748008
58mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.54748008
59mitochondrial respiratory chain complex I assembly (GO:0032981)3.54748008
60nuclear-transcribed mRNA catabolic process (GO:0000956)3.51448222
61protein localization to kinetochore (GO:0034501)3.50028577
62anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.49187954
63positive regulation of ligase activity (GO:0051351)3.48038643
64purine nucleobase biosynthetic process (GO:0009113)3.48004531
65regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.47394726
66kinetochore organization (GO:0051383)3.45271376
67positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.44373316
68rRNA modification (GO:0000154)3.42925606
69kinetochore assembly (GO:0051382)3.42549173
70DNA replication-independent nucleosome organization (GO:0034724)3.41263792
71DNA replication-independent nucleosome assembly (GO:0006336)3.41263792
72exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.41120490
73transcription-coupled nucleotide-excision repair (GO:0006283)3.40952741
74establishment of protein localization to mitochondrion (GO:0072655)3.40683553
75mitotic metaphase plate congression (GO:0007080)3.40606905
76spliceosomal complex assembly (GO:0000245)3.39977387
77negative regulation of ligase activity (GO:0051352)3.39065414
78negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.39065414
79cellular component biogenesis (GO:0044085)3.37120987
80termination of RNA polymerase III transcription (GO:0006386)3.35723009
81transcription elongation from RNA polymerase III promoter (GO:0006385)3.35723009
82mRNA catabolic process (GO:0006402)3.33310814
83regulation of ubiquitin-protein transferase activity (GO:0051438)3.32155744
84mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.31564587
85nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31322951
86protein localization to mitochondrion (GO:0070585)3.30673397
87ribosome assembly (GO:0042255)3.25069622
88DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.24191080
89RNA catabolic process (GO:0006401)3.21911362
90regulation of ligase activity (GO:0051340)3.20811326
91DNA ligation (GO:0006266)3.20386504
92intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.19492673
93signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.19492673
94regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.17266275
95signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.17228808
96signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.17228808
97signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.17228808
98inner mitochondrial membrane organization (GO:0007007)3.16533886
99viral mRNA export from host cell nucleus (GO:0046784)3.11596702
100signal transduction involved in DNA damage checkpoint (GO:0072422)3.11530613
101signal transduction involved in DNA integrity checkpoint (GO:0072401)3.11530613
102protein localization to chromosome, centromeric region (GO:0071459)3.11376737
103G1/S transition of mitotic cell cycle (GO:0000082)3.10635363
104cell cycle G1/S phase transition (GO:0044843)3.10635363
105nucleobase-containing small molecule interconversion (GO:0015949)3.09917932
106IMP biosynthetic process (GO:0006188)3.09152791
107ATP biosynthetic process (GO:0006754)3.08328647
108DNA replication-dependent nucleosome assembly (GO:0006335)3.08255403
109DNA replication-dependent nucleosome organization (GO:0034723)3.08255403
110signal transduction involved in cell cycle checkpoint (GO:0072395)3.07511105
111energy coupled proton transport, down electrochemical gradient (GO:0015985)3.06646944
112ATP synthesis coupled proton transport (GO:0015986)3.06646944
113cullin deneddylation (GO:0010388)3.06607414
114purine nucleoside triphosphate biosynthetic process (GO:0009145)3.02037831
115protein targeting to membrane (GO:0006612)3.01827593
1167-methylguanosine mRNA capping (GO:0006370)3.01603466
117histone exchange (GO:0043486)3.01424251
118regulation of cellular amino acid metabolic process (GO:0006521)3.00516289
119aerobic respiration (GO:0009060)2.99742503
120purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.99617118
121base-excision repair (GO:0006284)2.99593695
122positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.97904829
123metaphase plate congression (GO:0051310)2.97590186
124antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.97298736
1257-methylguanosine RNA capping (GO:0009452)2.97121045
126RNA capping (GO:0036260)2.97121045
127deoxyribonucleotide biosynthetic process (GO:0009263)2.94904690
128folic acid-containing compound biosynthetic process (GO:0009396)2.88850041
129attachment of spindle microtubules to kinetochore (GO:0008608)2.88281621
130pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.87684188

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.44839305
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.61368616
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.17997562
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.69891528
5* EST1_17652178_ChIP-ChIP_JURKAT_Human3.40481994
6* GABP_17652178_ChIP-ChIP_JURKAT_Human3.31393226
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.28387525
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.25399721
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.16976356
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.13744769
11* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.11275466
12FOXM1_23109430_ChIP-Seq_U2OS_Human3.10791584
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.96175094
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.95660661
15* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.90086859
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.89994501
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.78439063
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.73416568
19* XRN2_22483619_ChIP-Seq_HELA_Human2.55451289
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.52085197
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.52013395
22VDR_23849224_ChIP-Seq_CD4+_Human2.38709589
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32448736
24DCP1A_22483619_ChIP-Seq_HELA_Human2.21644120
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.21098967
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.20732201
27FOXP3_21729870_ChIP-Seq_TREG_Human2.07725718
28* TTF2_22483619_ChIP-Seq_HELA_Human2.02185809
29* THAP11_20581084_ChIP-Seq_MESCs_Mouse2.00643533
30GABP_19822575_ChIP-Seq_HepG2_Human1.97041830
31* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.94014300
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88618368
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.86954832
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.84848482
35TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.82537323
36* SRF_21415370_ChIP-Seq_HL-1_Mouse1.75793747
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74078752
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73010399
39* ELK1_19687146_ChIP-ChIP_HELA_Human1.71414630
40E2F1_21310950_ChIP-Seq_MCF-7_Human1.70997890
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.70899230
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.69504540
43* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65893642
44AR_21909140_ChIP-Seq_LNCAP_Human1.65115092
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64953764
46* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.62888191
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.61908115
48CIITA_25753668_ChIP-Seq_RAJI_Human1.59769311
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57969020
50ZFX_18555785_ChIP-Seq_MESCs_Mouse1.54262182
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.53015209
52YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48911823
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47155132
54CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37979751
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37903389
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.34812493
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34469104
58ZNF263_19887448_ChIP-Seq_K562_Human1.32546357
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.31659878
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.31253505
61CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.28428998
62KDM5A_27292631_Chip-Seq_BREAST_Human1.27389085
63MYC_22102868_ChIP-Seq_BL_Human1.26424623
64PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.24207551
65STAT3_1855785_ChIP-Seq_MESCs_Mouse1.16536600
66CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13468999
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.13458220
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.12642399
69ELK1_22589737_ChIP-Seq_MCF10A_Human1.12301224
70SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.12238011
71MYC_18940864_ChIP-ChIP_HL60_Human1.11495573
72TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11145743
73E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09903041
74ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.09616233
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.08801894
76ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07952571
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07542507
78HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.06338310
79ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.04313287
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04084141
81SOX2_18555785_ChIP-Seq_MESCs_Mouse1.04063546
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.03957753
83* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03660108
84VDR_21846776_ChIP-Seq_THP-1_Human1.00791720
85DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00463890
86* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99964974
87* FOXP1_21924763_ChIP-Seq_HESCs_Human0.98560831
88TFEB_21752829_ChIP-Seq_HELA_Human0.97606388
89* SPI1_23547873_ChIP-Seq_NB4_Human0.97484972
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97349371
91KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.97152197
92SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96437000
93EGR1_19374776_ChIP-ChIP_THP-1_Human0.95115592
94KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94690677
95* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93773397
96TP63_19390658_ChIP-ChIP_HaCaT_Human0.92600723
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.92417772
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.91500686
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91013547
100HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90299438
101TET1_21451524_ChIP-Seq_MESCs_Mouse0.87143584
102HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.86537626
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83686327
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.83383440
105* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.82857169
106NANOG_16153702_ChIP-ChIP_HESCs_Human0.82497164
107CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81189624
108RBPJ_22232070_ChIP-Seq_NCS_Mouse0.80658775
109TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80049017
110SRY_22984422_ChIP-ChIP_TESTIS_Rat0.79513835
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.79432400
112* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78134328
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.77915335
114* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77191693
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.76970457
116CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.74706108

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.66779062
2MP0004957_abnormal_blastocyst_morpholog4.62606172
3MP0010094_abnormal_chromosome_stability4.48345184
4MP0003111_abnormal_nucleus_morphology4.20803342
5MP0003077_abnormal_cell_cycle3.97707758
6MP0008057_abnormal_DNA_replication3.81208351
7MP0008058_abnormal_DNA_repair3.44326806
8MP0008007_abnormal_cellular_replicative2.97678026
9MP0008932_abnormal_embryonic_tissue2.87460306
10MP0009379_abnormal_foot_pigmentation2.74804648
11MP0002396_abnormal_hematopoietic_system2.42400313
12MP0003786_premature_aging2.20971426
13MP0000490_abnormal_crypts_of2.08428929
14MP0000350_abnormal_cell_proliferation1.99492017
15MP0001730_embryonic_growth_arrest1.98587860
16MP0003123_paternal_imprinting1.96918496
17MP0009697_abnormal_copulation1.92541368
18MP0003806_abnormal_nucleotide_metabolis1.87362798
19MP0001346_abnormal_lacrimal_gland1.69789736
20MP0003136_yellow_coat_color1.66548121
21MP0009333_abnormal_splenocyte_physiolog1.64752318
22MP0003186_abnormal_redox_activity1.59469012
23MP0003718_maternal_effect1.58231868
24MP0000313_abnormal_cell_death1.53735022
25MP0003315_abnormal_perineum_morphology1.52381324
26MP0003763_abnormal_thymus_physiology1.52079599
27MP0010030_abnormal_orbit_morphology1.50718819
28MP0002019_abnormal_tumor_incidence1.49616466
29MP0002132_abnormal_respiratory_system1.48437587
30MP0001697_abnormal_embryo_size1.46646047
31MP0002080_prenatal_lethality1.40520667
32MP0008877_abnormal_DNA_methylation1.40249786
33MP0006292_abnormal_olfactory_placode1.39557875
34MP0006036_abnormal_mitochondrial_physio1.38962649
35MP0000749_muscle_degeneration1.37489311
36MP0004808_abnormal_hematopoietic_stem1.36816685
37MP0010352_gastrointestinal_tract_polyps1.36510085
38MP0005397_hematopoietic_system_phenotyp1.32745576
39MP0001545_abnormal_hematopoietic_system1.32745576
40MP0001672_abnormal_embryogenesis/_devel1.32513750
41MP0005380_embryogenesis_phenotype1.32513750
42MP0006054_spinal_hemorrhage1.32107303
43MP0003567_abnormal_fetal_cardiomyocyte1.28520791
44MP0001853_heart_inflammation1.22365485
45MP0004133_heterotaxia1.21327637
46MP0002398_abnormal_bone_marrow1.20954151
47MP0006035_abnormal_mitochondrial_morpho1.20633795
48MP0000566_synostosis1.19896738
49MP0009672_abnormal_birth_weight1.19278929
50MP0005499_abnormal_olfactory_system1.18830657
51MP0005394_taste/olfaction_phenotype1.18830657
52MP0003984_embryonic_growth_retardation1.18311391
53MP0002085_abnormal_embryonic_tissue1.17752772
54MP0000703_abnormal_thymus_morphology1.16111584
55MP0002722_abnormal_immune_system1.15943797
56MP0005075_abnormal_melanosome_morpholog1.15579630
57MP0002088_abnormal_embryonic_growth/wei1.13899858
58MP0000358_abnormal_cell_content/1.09211553
59MP0000858_altered_metastatic_potential1.08920914
60MP0002210_abnormal_sex_determination1.08612162
61MP0000751_myopathy1.08023131
62MP0005174_abnormal_tail_pigmentation1.07996491
63MP0000689_abnormal_spleen_morphology1.07939866
64MP0002160_abnormal_reproductive_system1.05824661
65MP0005330_cardiomyopathy1.04862618
66MP0001881_abnormal_mammary_gland1.04711254
67MP0008995_early_reproductive_senescence1.02330640
68MP0005501_abnormal_skin_physiology1.02306025
69MP0001293_anophthalmia1.01567006
70MP0002234_abnormal_pharynx_morphology1.01015176
71MP0002429_abnormal_blood_cell0.98730172
72MP0002086_abnormal_extraembryonic_tissu0.97735342
73MP0010307_abnormal_tumor_latency0.96621505
74MP0001145_abnormal_male_reproductive0.95422011
75MP0002095_abnormal_skin_pigmentation0.95267062
76MP0000762_abnormal_tongue_morphology0.94828090
77MP0002084_abnormal_developmental_patter0.93892593
78MP0002938_white_spotting0.93184478
79MP0004197_abnormal_fetal_growth/weight/0.91897839
80MP0006072_abnormal_retinal_apoptosis0.91387798
81MP0004147_increased_porphyrin_level0.89483151
82MP0009053_abnormal_anal_canal0.88632410
83MP0002697_abnormal_eye_size0.87693146
84MP0001835_abnormal_antigen_presentation0.87026906
85MP0002282_abnormal_trachea_morphology0.85054610
86MP0005084_abnormal_gallbladder_morpholo0.84770455
87MP0005408_hypopigmentation0.84282211
88MP0000716_abnormal_immune_system0.82616485
89MP0002277_abnormal_respiratory_mucosa0.81773180
90MP0002102_abnormal_ear_morphology0.81137989
91MP0001286_abnormal_eye_development0.80919488
92MP0005389_reproductive_system_phenotype0.80483588
93MP0001905_abnormal_dopamine_level0.80133841
94MP0000653_abnormal_sex_gland0.79245124
95MP0001929_abnormal_gametogenesis0.78982066
96MP0004233_abnormal_muscle_weight0.78363083
97MP0003890_abnormal_embryonic-extraembry0.77401417
98MP0001119_abnormal_female_reproductive0.76526847
99MP0000537_abnormal_urethra_morphology0.75042079
100MP0002796_impaired_skin_barrier0.74258315
101MP0008789_abnormal_olfactory_epithelium0.73139665
102MP0003938_abnormal_ear_development0.72346301
103MP0001529_abnormal_vocalization0.72061606
104MP0003121_genomic_imprinting0.71862925
105MP0001764_abnormal_homeostasis0.71474691
106MP0005266_abnormal_metabolism0.71003485
107MP0005671_abnormal_response_to0.70472750
108MP0002233_abnormal_nose_morphology0.69745012
109MP0009785_altered_susceptibility_to0.69411946
110MP0000750_abnormal_muscle_regeneration0.68712894
111MP0003937_abnormal_limbs/digits/tail_de0.68618343
112MP0003941_abnormal_skin_development0.68488060
113MP0000685_abnormal_immune_system0.67344109
114MP0003942_abnormal_urinary_system0.67253555
115MP0002163_abnormal_gland_morphology0.66328133
116MP0002420_abnormal_adaptive_immunity0.66130824
117MP0002405_respiratory_system_inflammati0.65766073
118MP0005384_cellular_phenotype0.65378050
119MP0002736_abnormal_nociception_after0.65147269
120MP0001727_abnormal_embryo_implantation0.64992273
121MP0002653_abnormal_ependyma_morphology0.64908765
122MP0001819_abnormal_immune_cell0.64886038
123MP0003221_abnormal_cardiomyocyte_apopto0.64468425
124MP0002751_abnormal_autonomic_nervous0.63967186
125MP0000372_irregular_coat_pigmentation0.60782266
126MP0000049_abnormal_middle_ear0.60627960
127MP0002111_abnormal_tail_morphology0.60574628
128MP0000477_abnormal_intestine_morphology0.59495018
129MP0003119_abnormal_digestive_system0.58808545
130MP0001800_abnormal_humoral_immune0.58652951
131MP0002249_abnormal_larynx_morphology0.57846778
132MP0002148_abnormal_hypersensitivity_rea0.57194623
133MP0005395_other_phenotype0.56886318
134MP0005025_abnormal_response_to0.56886086
135MP0000015_abnormal_ear_pigmentation0.56780317
136MP0001919_abnormal_reproductive_system0.56165348
137MP0005083_abnormal_biliary_tract0.56090872
138MP0002161_abnormal_fertility/fecundity0.54496711
139MP0009250_abnormal_appendicular_skeleto0.53053500
140MP0000627_abnormal_mammary_gland0.52226332
141MP0005257_abnormal_intraocular_pressure0.51123587
142MP0003385_abnormal_body_wall0.50232882

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.50890185
2Abnormal number of erythroid precursors (HP:0012131)6.30307663
3Reticulocytopenia (HP:0001896)5.81388651
4Birth length less than 3rd percentile (HP:0003561)4.37101999
5Aplastic anemia (HP:0001915)4.06151495
6Oral leukoplakia (HP:0002745)4.01321608
7Macrocytic anemia (HP:0001972)4.01013982
8Pallor (HP:0000980)3.89407507
9Cerebral edema (HP:0002181)3.80730167
10Breast hypoplasia (HP:0003187)3.47105404
11Decreased activity of mitochondrial respiratory chain (HP:0008972)3.27033261
12Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.27033261
13Colon cancer (HP:0003003)3.22526064
14Acute necrotizing encephalopathy (HP:0006965)3.18004672
15Increased muscle lipid content (HP:0009058)3.17643907
16Mitochondrial inheritance (HP:0001427)3.16103442
17Rough bone trabeculation (HP:0100670)3.13425806
18Hepatocellular necrosis (HP:0001404)3.05025274
19Chromsome breakage (HP:0040012)3.02756646
20Increased CSF lactate (HP:0002490)2.95971399
21Abnormal mitochondria in muscle tissue (HP:0008316)2.94432070
22Aplasia/Hypoplasia of the sacrum (HP:0008517)2.91789495
23Chromosomal breakage induced by crosslinking agents (HP:0003221)2.91062222
24Microretrognathia (HP:0000308)2.90184611
2511 pairs of ribs (HP:0000878)2.90183684
26Selective tooth agenesis (HP:0001592)2.89761045
27Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.87614961
28Degeneration of anterior horn cells (HP:0002398)2.87468076
29Abnormality of the anterior horn cell (HP:0006802)2.87468076
30Increased hepatocellular lipid droplets (HP:0006565)2.87100071
31Type I transferrin isoform profile (HP:0003642)2.86869117
32Carpal bone hypoplasia (HP:0001498)2.86037082
33Patellar aplasia (HP:0006443)2.83742698
34Progressive muscle weakness (HP:0003323)2.80095075
35Increased serum lactate (HP:0002151)2.77220242
36Abnormality of the preputium (HP:0100587)2.75725072
37Cerebral hypomyelination (HP:0006808)2.71215618
38Absent thumb (HP:0009777)2.69338477
39Hepatic necrosis (HP:0002605)2.68605352
40Meckel diverticulum (HP:0002245)2.66463983
41Aplasia/Hypoplasia of the patella (HP:0006498)2.65403991
42Thrombocytosis (HP:0001894)2.64018214
43Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.62827944
44Premature graying of hair (HP:0002216)2.62217868
45Trismus (HP:0000211)2.60939525
46Leukodystrophy (HP:0002415)2.60102378
47Abnormality of the ileum (HP:0001549)2.59157522
48Multiple enchondromatosis (HP:0005701)2.57914213
493-Methylglutaconic aciduria (HP:0003535)2.54226878
50Exertional dyspnea (HP:0002875)2.53893775
51Lipid accumulation in hepatocytes (HP:0006561)2.49141110
52Acute encephalopathy (HP:0006846)2.45073719
53Abnormality of chromosome stability (HP:0003220)2.39838085
54Testicular atrophy (HP:0000029)2.38488927
55Abnormal number of incisors (HP:0011064)2.37192102
56Pancytopenia (HP:0001876)2.36086409
57Abnormality of the heme biosynthetic pathway (HP:0010472)2.35529740
58Bone marrow hypocellularity (HP:0005528)2.32167865
59Progressive macrocephaly (HP:0004481)2.31591654
60Exercise intolerance (HP:0003546)2.31342363
61Respiratory difficulties (HP:0002880)2.30043280
62Amniotic constriction ring (HP:0009775)2.29933318
63Abnormality of placental membranes (HP:0011409)2.29933318
64Myelodysplasia (HP:0002863)2.28738252
65Lethargy (HP:0001254)2.28352922
66Optic disc pallor (HP:0000543)2.27783810
67Aplasia/Hypoplasia of the uvula (HP:0010293)2.26663264
68Abnormal gallbladder physiology (HP:0012438)2.23301076
69Cholecystitis (HP:0001082)2.23301076
70Abnormal trabecular bone morphology (HP:0100671)2.22227859
71Emotional lability (HP:0000712)2.21164050
72Cellular immunodeficiency (HP:0005374)2.20398903
73Abnormality of reticulocytes (HP:0004312)2.18526380
74Increased intramyocellular lipid droplets (HP:0012240)2.18309374
75Medulloblastoma (HP:0002885)2.18108078
76Triphalangeal thumb (HP:0001199)2.17884797
77Small intestinal stenosis (HP:0012848)2.14497364
78Duodenal stenosis (HP:0100867)2.14497364
79Muscle fiber atrophy (HP:0100295)2.13742530
80Abnormality of glycolysis (HP:0004366)2.12728261
81Increased serum pyruvate (HP:0003542)2.12728261
82Absent radius (HP:0003974)2.12706889
83Neoplasm of the pancreas (HP:0002894)2.12183565
84Cleft eyelid (HP:0000625)2.09122413
85Tracheoesophageal fistula (HP:0002575)2.07194042
86Microvesicular hepatic steatosis (HP:0001414)2.06852790
87Abnormal lung lobation (HP:0002101)2.06744771
88Duplicated collecting system (HP:0000081)2.06226621
89CNS demyelination (HP:0007305)2.05282775
90Agnosia (HP:0010524)2.04563270
91Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.03948666
92Abnormality of renal resorption (HP:0011038)2.03309045
93Reduced antithrombin III activity (HP:0001976)2.02753759
94Secondary amenorrhea (HP:0000869)2.01792268
95Premature ovarian failure (HP:0008209)2.01032489
96Lactic acidosis (HP:0003128)2.00892834
97IgM deficiency (HP:0002850)2.00881278
98Renal Fanconi syndrome (HP:0001994)1.99952439
99Horseshoe kidney (HP:0000085)1.99765354
100Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.98249344
101Abnormal protein N-linked glycosylation (HP:0012347)1.98249344
102Abnormal protein glycosylation (HP:0012346)1.98249344
103Abnormal glycosylation (HP:0012345)1.98249344
104Absent forearm bone (HP:0003953)1.97974541
105Aplasia involving forearm bones (HP:0009822)1.97974541
106Nemaline bodies (HP:0003798)1.97057753
107Respiratory failure (HP:0002878)1.93886955
108Glossoptosis (HP:0000162)1.90589061
109Type 2 muscle fiber atrophy (HP:0003554)1.88735507
110Abnormality of the umbilical cord (HP:0010881)1.86168430
111Asplenia (HP:0001746)1.85925106
112Hypoplasia of the radius (HP:0002984)1.85263222
113Methylmalonic aciduria (HP:0012120)1.85139654
114Lymphoma (HP:0002665)1.84013971
115Sloping forehead (HP:0000340)1.82583494
116Abnormality of dicarboxylic acid metabolism (HP:0010995)1.81966410
117Dicarboxylic aciduria (HP:0003215)1.81966410
118Abnormality of methionine metabolism (HP:0010901)1.81870046
119Atresia of the external auditory canal (HP:0000413)1.80512602
120Ragged-red muscle fibers (HP:0003200)1.80287397
121Abnormality of the renal collecting system (HP:0004742)1.80278616
122Abnormalities of placenta or umbilical cord (HP:0001194)1.78796217
123Gout (HP:0001997)1.78688023
124Hyperphosphaturia (HP:0003109)1.77700678
125X-linked dominant inheritance (HP:0001423)1.72831552
126Absent septum pellucidum (HP:0001331)1.71578715
127Methylmalonic acidemia (HP:0002912)1.66179380
128Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.66025412
129Generalized aminoaciduria (HP:0002909)1.63700657
130Muscle fiber inclusion bodies (HP:0100299)1.62213648
131* Sparse eyelashes (HP:0000653)1.56154204
132Septo-optic dysplasia (HP:0100842)1.55608630
133Hypoplasia of the capital femoral epiphysis (HP:0003090)1.55563254

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.02547371
2WEE14.30523693
3* VRK23.94698963
4NME23.56075474
5STK163.49097259
6EIF2AK13.25843077
7CDC73.23746297
8SRPK12.46282310
9TESK22.46197882
10EIF2AK32.10741873
11TAF12.06378876
12PLK42.05869363
13PIM22.02961068
14ACVR1B2.01612929
15NEK22.01257253
16BRSK22.01165837
17PLK11.78103961
18TSSK61.74159708
19TTK1.73049360
20CDK71.72685172
21RPS6KB21.72390096
22NEK11.71279192
23PASK1.60779449
24SMG11.58985729
25MKNK11.58914253
26AURKB1.57908110
27TLK11.54180513
28DYRK31.53734189
29NUAK11.51646818
30KDR1.45557086
31ATR1.42813873
32CCNB11.39661250
33AURKA1.34659772
34BRSK11.33662137
35NME11.29916434
36TESK11.26960716
37TGFBR11.25568380
38MUSK1.22768208
39CDK81.22267295
40RPS6KA41.22038325
41PAK41.18045384
42SCYL21.12903425
43PLK31.09590583
44CHEK21.08209578
45MAP3K111.07820471
46MAP3K81.06179109
47LRRK21.05170649
48MAPKAPK31.04396951
49PBK0.97430282
50CDK40.97055447
51MKNK20.96275652
52MAP4K10.95866180
53EIF2AK20.92578182
54STK100.91317152
55EPHA20.86860670
56STK40.85806877
57MST40.85661950
58CHEK10.83658121
59ILK0.82121982
60PIM10.80251627
61CSNK2A10.79975062
62LIMK10.77804727
63ZAK0.77158861
64BRAF0.76356513
65PAK10.75472903
66CSNK2A20.73917405
67DYRK20.73884020
68CDK190.73874885
69IRAK40.73577461
70PDK20.73415194
71BCKDK0.71693673
72EEF2K0.69120831
73BTK0.65055064
74FLT30.64179863
75CSNK1G30.61543911
76MAP2K30.61415654
77ABL20.59735724
78TRIM280.59018055
79DAPK30.57090413
80CDK20.57006530
81TEC0.56991332
82MAPKAPK50.55391628
83ATM0.54805941
84* VRK10.54061783
85ERBB40.53821579
86PRKCI0.53344647
87EPHB20.52755903
88MAP3K100.49357538
89LMTK20.49095369
90MST1R0.48949643
91CLK10.48755600
92DAPK10.47774339
93YES10.44186715
94RPS6KA50.44067018
95TAOK20.43398570
96PNCK0.43051541
97CSNK1G10.41118066
98KIT0.41007459
99CDK140.39969192
100CDK10.39796712
101BLK0.39149192
102CDK150.38966009
103CDK180.38530838
104ARAF0.36163868
105CDK90.35629258
106GRK60.35557594
107PHKG20.35407016
108PHKG10.35407016
109IRAK30.35133459
110AKT20.34403980
111CAMK2G0.33852766
112MAP4K20.33665376
113MYLK0.33469109
114ZAP700.33374619
115IKBKB0.30336202
116ALK0.29185112
117MAP3K120.28810207
118LYN0.28521904
119CSNK1G20.28176187
120CSNK1E0.28077990
121CSNK1A1L0.27188961
122MAPKAPK20.23638640
123RPS6KA60.21874521
124CDK11A0.21692512
125RPS6KC10.20827234
126RPS6KL10.20827234
127OBSCN0.20688439
128CSF1R0.20404550

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.07199162
2DNA replication_Homo sapiens_hsa030304.97042774
3Mismatch repair_Homo sapiens_hsa034304.07220399
4Proteasome_Homo sapiens_hsa030503.99596312
5RNA polymerase_Homo sapiens_hsa030203.49606198
6Spliceosome_Homo sapiens_hsa030403.25483214
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.18358833
8Homologous recombination_Homo sapiens_hsa034403.03627968
9Base excision repair_Homo sapiens_hsa034103.02620774
10Nucleotide excision repair_Homo sapiens_hsa034202.82449650
11Pyrimidine metabolism_Homo sapiens_hsa002402.75454630
12RNA transport_Homo sapiens_hsa030132.58857183
13Cell cycle_Homo sapiens_hsa041102.17225953
14One carbon pool by folate_Homo sapiens_hsa006702.10211984
15Fanconi anemia pathway_Homo sapiens_hsa034602.02468498
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.00011483
17Parkinsons disease_Homo sapiens_hsa050121.91354970
18Oxidative phosphorylation_Homo sapiens_hsa001901.85533326
19RNA degradation_Homo sapiens_hsa030181.83024841
20Non-homologous end-joining_Homo sapiens_hsa034501.79991745
21Basal transcription factors_Homo sapiens_hsa030221.67772273
22Huntingtons disease_Homo sapiens_hsa050161.61575686
23Protein export_Homo sapiens_hsa030601.51096906
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.48908461
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45653063
26Purine metabolism_Homo sapiens_hsa002301.44238214
27Fatty acid elongation_Homo sapiens_hsa000621.42736568
28Pyruvate metabolism_Homo sapiens_hsa006201.31726399
29p53 signaling pathway_Homo sapiens_hsa041151.30803836
30mRNA surveillance pathway_Homo sapiens_hsa030151.18430056
31Alzheimers disease_Homo sapiens_hsa050101.07070349
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.06213065
33Epstein-Barr virus infection_Homo sapiens_hsa051691.05575794
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89018931
35Folate biosynthesis_Homo sapiens_hsa007900.88471020
36Pentose phosphate pathway_Homo sapiens_hsa000300.85443083
37Sulfur relay system_Homo sapiens_hsa041220.81765551
38Propanoate metabolism_Homo sapiens_hsa006400.78150160
39Systemic lupus erythematosus_Homo sapiens_hsa053220.76394023
40Herpes simplex infection_Homo sapiens_hsa051680.75137576
41Cysteine and methionine metabolism_Homo sapiens_hsa002700.71430723
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71227687
43Antigen processing and presentation_Homo sapiens_hsa046120.70457203
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70348376
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69573853
46Glutathione metabolism_Homo sapiens_hsa004800.69086898
47Cyanoamino acid metabolism_Homo sapiens_hsa004600.68675261
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66925287
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66626741
50Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.65899552
51Primary immunodeficiency_Homo sapiens_hsa053400.64952465
52Biosynthesis of amino acids_Homo sapiens_hsa012300.64083360
53Drug metabolism - other enzymes_Homo sapiens_hsa009830.63564169
54Vitamin B6 metabolism_Homo sapiens_hsa007500.62826809
55Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61215939
56N-Glycan biosynthesis_Homo sapiens_hsa005100.58675424
57Oocyte meiosis_Homo sapiens_hsa041140.57902728
58Viral carcinogenesis_Homo sapiens_hsa052030.54608136
59Sulfur metabolism_Homo sapiens_hsa009200.52202648
60Legionellosis_Homo sapiens_hsa051340.51906878
61HTLV-I infection_Homo sapiens_hsa051660.51027307
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50850534
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.48517104
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48142355
65Cardiac muscle contraction_Homo sapiens_hsa042600.47754707
66Tyrosine metabolism_Homo sapiens_hsa003500.45735424
67Carbon metabolism_Homo sapiens_hsa012000.45035751
68Thyroid cancer_Homo sapiens_hsa052160.42366049
69Peroxisome_Homo sapiens_hsa041460.41663283
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41588073
71Metabolic pathways_Homo sapiens_hsa011000.41527108
72Steroid biosynthesis_Homo sapiens_hsa001000.40662726
73Phenylalanine metabolism_Homo sapiens_hsa003600.40444547
74Vibrio cholerae infection_Homo sapiens_hsa051100.40211778
75Fructose and mannose metabolism_Homo sapiens_hsa000510.37129870
76Selenocompound metabolism_Homo sapiens_hsa004500.36421350
77Shigellosis_Homo sapiens_hsa051310.35460144
782-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34721930
79Apoptosis_Homo sapiens_hsa042100.32991021
80Arachidonic acid metabolism_Homo sapiens_hsa005900.32610700
81Galactose metabolism_Homo sapiens_hsa000520.31602512
82Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29794290
83Hematopoietic cell lineage_Homo sapiens_hsa046400.29387708
84Small cell lung cancer_Homo sapiens_hsa052220.28660286
85Measles_Homo sapiens_hsa051620.28437713
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26865682
87Fatty acid metabolism_Homo sapiens_hsa012120.26569723
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24469974
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24027325
90Butanoate metabolism_Homo sapiens_hsa006500.23096341
91Asthma_Homo sapiens_hsa053100.22578744
92Allograft rejection_Homo sapiens_hsa053300.22463640
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.22148421
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21449769
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21019506
96Intestinal immune network for IgA production_Homo sapiens_hsa046720.19378565
97RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18755865
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18506635
99Hepatitis B_Homo sapiens_hsa051610.18045084
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.17293341
101beta-Alanine metabolism_Homo sapiens_hsa004100.16921997
102Alcoholism_Homo sapiens_hsa050340.15773555
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15715000
104Viral myocarditis_Homo sapiens_hsa054160.13758115
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.13497237
106Collecting duct acid secretion_Homo sapiens_hsa049660.13490859
107Bladder cancer_Homo sapiens_hsa052190.13461858
108MicroRNAs in cancer_Homo sapiens_hsa052060.13295560
109Colorectal cancer_Homo sapiens_hsa052100.12618049
110Basal cell carcinoma_Homo sapiens_hsa052170.12013894
111Renin-angiotensin system_Homo sapiens_hsa046140.11962878
112TGF-beta signaling pathway_Homo sapiens_hsa043500.11881889
113Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.10013748
114Influenza A_Homo sapiens_hsa051640.09876043
115HIF-1 signaling pathway_Homo sapiens_hsa040660.09783618
116SNARE interactions in vesicular transport_Homo sapiens_hsa041300.09748512
117Notch signaling pathway_Homo sapiens_hsa043300.09388747
118Vitamin digestion and absorption_Homo sapiens_hsa049770.08799666
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.07454478
120Pathways in cancer_Homo sapiens_hsa052000.07402469
121Graft-versus-host disease_Homo sapiens_hsa053320.06994619
122Wnt signaling pathway_Homo sapiens_hsa043100.06248051
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.06006907
124Chemical carcinogenesis_Homo sapiens_hsa052040.05800786
125Arginine and proline metabolism_Homo sapiens_hsa003300.05256204
126Linoleic acid metabolism_Homo sapiens_hsa005910.04674439
127Hedgehog signaling pathway_Homo sapiens_hsa043400.04346957
128Hippo signaling pathway_Homo sapiens_hsa043900.03603718
129Fatty acid degradation_Homo sapiens_hsa000710.01578244
130Arginine biosynthesis_Homo sapiens_hsa00220-0.0286217
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533-0.0100728
132Drug metabolism - cytochrome P450_Homo sapiens_hsa00982-0.0065244

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